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<~~ HP CALCULATORS SOLVE YOUR PROBLEMS, YOUR WAY Let Our Research Take The Work Out Of Yours. If data analysis is your problem HP has developed the statistical tools you need for speeding research and cutting costs. These fast acculrate conmputation systems can handle any task from routine data reduction and examination all the way up to advanced statistical and mathematical analysis. Are you doing applied research? Basic stat analysis? Then your answer is the HP 9805. This preprogrammed, desk-top calculator is specifically designed for people who don't have time for the numbers game-for tedious scratch-pad calculations, slide rules, handbooks, and charts. It will calculate and print your solution at the press of a key: linear and parabolic curve fits, mean and standard deviation, correlation coefficients, histograms, and t for paired and unpaired data. And that's the minimum system! Think what you can do with Expanded Stat functions and a plotter! And the basic system is just $12951. But what if you're doing pure research that calls for large, sophisticated stat analysis? We can help you there, too. With our versatile, programmable HP 9830. You get desk-top convenience, combined with computer-like power. More than enough power for things like stepxwise regression of up to 30 variables with correlation analysis, or four-way factorial analysis. The 9830 makes short work of probit analysis, RIA and just about any other statistical problem you're likely to encounter. And it accommodates a complete range of input and output peripherals. Best of all, it leases for under $300* per month. So, let our research take the work out of yours. Especially since you can save money in the bargain. Call or write for more information or a hands-on demonstration. D)omestic ISA pric 's onl // HEWLETTh PACKARD Sales, service and support in 172 centers in 65 countries P O Bo. :3'1 .Io 8053/ Hewrlett-Pac kard, P.O. Box 30)1. Loveland. Colorido 80)537 would like to know miiore about your stat solutions :- Informnition oniv L: Hands-on demonstration Namiie I Addre ss _ Philile M\! primairx application is: I S1/747 Circle Reader's Service No. 17 for information and No. 18 for demonstration - I t I I

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<~~HP CALCULATORS SOLVE YOUR PROBLEMS, YOUR WAY

Let Our Research TakeThe Work Out Of Yours.If data analysis is your problem HP hasdeveloped the statistical tools you need forspeeding research and cutting costs. These fastacculrate conmputation systems can handle any taskfrom routine data reduction and examination allthe way up to advanced statistical andmathematical analysis.Are you doing applied research? Basic stat

analysis? Then your answer is the HP 9805. Thispreprogrammed, desk-top calculator is specificallydesigned for people who don't have time for thenumbers game-for tedious scratch-padcalculations, slide rules, handbooks, and charts. Itwill calculate and print your solution at the press

of a key: linear and parabolic curve fits, mean andstandard deviation, correlation coefficients,histograms, and t for paired and unpaired data.And that's the minimum system! Think what youcan do with Expanded Stat functions and a

plotter! And the basic system is just $12951.But what if you're doing pure research that calls

for large, sophisticated stat analysis? We can help youthere, too. With our versatile, programmable HP9830. You get desk-top convenience, combined withcomputer-like power. More than enough power forthings like stepxwise regression of up to 30variables with correlation analysis, or four-wayfactorial analysis. The 9830 makes short work ofprobit analysis, RIA and just about any otherstatistical problem you're likely to encounter. Andit accommodates a complete range of input andoutput peripherals. Best of all, it leases for under$300* per month.

So, let our research take the work out of yours.Especially since you can save money in thebargain. Call or write for more information or a

hands-on demonstration.D)omestic ISA pric 's onl

//

HEWLETTh PACKARD

Sales, service and support in 172 centers in 65 countriesP O Bo. :3'1 .Io 8053/

Hewrlett-Pac kard, P.O. Box 30)1.Loveland. Colorido 80)537

would like to know miiore about your stat solutions:- Informnition oniv L: Hands-on demonstrationNamiie

I Address _

Philile

M\! primairx application is:I

S1/747Circle Reader's Service No. 17 for information and No. 18 for demonstration

-

ItII

When degrees count-count on REVCO.

Rev co performance an(l dependability aren'tclaims - they're facts. Our long list of custo-mers served - and satisfied - bears this out.Whatever your ULTra-Low® temperature neecl,Revco supplies a widie range of freezers, bothupright and chest, for scientific and industrialapplication. And with our Inventory ControlSystem we'll adapt any unit to your in(livi(lualrequirements. Freezers from 1.5 to 25 cubic feet

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152

1850), noting that the atomic weightsof various elements were almost exactlyinteger multiples of the atomic weightof hydrogen, inferred that atoms ofvarious elements consisted of commonconstituents. He correctly recognizedthat the relationship, although notexactly true, pointed toward a basicscientific law. At the other extreme, allfour presidents of the United Stateswho have been assassinated in officehave been elected in years ending inzero. In spite of the low a priori prob-ability of this occurring, no one wouldseriously suLggest that this points to aphysical or sociological law.

Since 1971, two more World Serieshave lasted seven games. The proba-bility of a single series of evenlvmatched teamns lasting seven games is

1=(2 =6

where C is the binomial coefficient.The probability of two successive

series lasting seven games is therefore25/256, or approximately 0.1. Whilenot quite as improbable as the reputedloss of two vital magnetic tapes, this isnevertheless somewhat surprising.Now that 17 of the 29 World Series

played since the end of World War IIhave lasted seven games, one finds thatthe probability of this occurring as arandom event (between evenly matchedteams) wotuld be

29

E Cn p- (1 - P)9 = 0.0021it = 17

And, of the 21 World Series that havegone to the sixth game since the endof World War II, the team that wasahead, going into the sixth game, hasstill won only four times. If the teamsare evenly matched, the probability ofwinning less than five times is now

C (2)Iin 0.0036

This "back-to-the-wall" effect, whichtends to favor the trailing team in thesixth game, has occurred only sincethe end of World War II. Once again,one is forced to ask whether this un-usual occurrence of seven-game WorldScries is aI statistical freak or whether.like Prout's hypothesis, it suggests theexistence of some hitherto undetectedpheniomeiion.

WILLIAM SIMONSchool of AMedicine and Dentis try,Unhiersity of Rochlester,Rochester. Neew York 14642

SCIENCF. VOl 18Xt

_________ Separation,N." Aand

Depression

Edited by/ ~~~~John Paul Scott

a aaa 0St0 XandEdward Senay

This volume brings together contributions from behavioralbiology, animal behavior studies, clinical psychopharma-cology, psychoanalysis, and social systems research and,thus, bridges the gaps between animal behavior modelsand the human clinical situation.

256 pages. Illustrations and tables. A comprehensive index,and references. Retail price: $19.95. AAAS Member price(with check accompanying order): $16.95. ISBN-087168-094-7

Send orders to Department SD

A A A SAMERICAN ASSOCIATION for theADVANCEMENT of SCIENCE1515 Massachusetts Avenue, N.W.Washington, D. C. 20005

6--

"to Itop I I

.0A:"I.00 0 0 0

If determination of the low levels of 3-hydroxy-3-methylglutaryl coenzyme A reductase activity isyour problem, you will find this new radioactivesubstrate useful.It will permit you to study factors involved inregulation of activity of the rate-limiting enzyme inthe cholesterol biosynthesis: conversion of HMG-CoAto mevalonate.*

'Reference: Brown, M.S., Dana, S.E. and Goldstein, J.L.,Regulation of 3-Hydroxy-3-Methylglutaryl Coenzyme AReductase Activity in Human Fibroblasts by Lipoproteins,Proc. Nat. Acad-Sci, USA, 70, No. 7,2162-2166, 1973.

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Circle No. 110 on Reoders' Service Card

External recorder trace ofdensitometer scan and Integrate signals

SCANNINGINTEGRATING

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No other electrophoresis densitometer scan-ning in the visible light range can match the EC910 for value and versatility at any price.

Check these features:* accepts whole slabs or columns* electronic integration* connects to all millivolt recorders* two scan speeds for best resolution* slit sizes from 0.1 mm for 50 micron resolutionb* interchangeable filters in visible spectrum

* templates available for all supporting media* compact, lightweight, solid state

Need proof? Send us a troublesome pattern.We'll scan and integrate it and return it to you

with a complete report. For more information

call collect 813-344-1644 or write E-C ApparatusCorp., 3831 Tyrone Blvd. N., St. Petersburg,

Florida 33709.

ag ~ ~ ~~Circle No 71 on Readers' Service Card18 JANUARY 1974 153

Most ofyour Blo Med problemscan be solved by an unknown.

Say goodbye to time sharing. Give the pocketcalculator to your kids. Stop wasting your timedoing math with a pencil.

If you've got statistical problems, we've gota solution. The Compucorp Micro Statistician.The professional's machine.

The Statistician is a hand-held, batteryoperable Micro Computer that thinks the wayyou think.

It does blood gas analyses. Works chemistryproblems. Breezes through medical calculations.Cures pathological headaches. Separatesmedical facts from fiction.

The Micro Statistician is the first and onlyhand-held Micro Computer with built-in standarddeviation (grouped or ungrouped), linearregression, z-score, t-dependent and independent,logs and anti-logs, coefficient or correlation,expected y from regression coefficients, slopeand intercept.

The Micro Statistician is also the first hand-held statistical machine that's programmable.It allows you to have two 80-step programs inmemory at the same time. Which means

repetitive calculations are a snap. You can do register arithmetic in and out of all ten storage regis-tens. And you can set the decimal point anywhere you want it. And change it whenever you want to.

The Compucorp Statistician is the first hand-held machine with 13-digit accuracy and a big,bright 10-digit display. It's also the first one with an algebraic keyboard and nested parentheses.

Get all the facts on Compucorp Micro Computers. We may be an unknownto you, but we're already solving tough Bio Med problems around the world.

See your local Compucorp dealer. Or write Computer Design Corporation,12401 Olympic Boulevard, Los Angeles, Califoria 90064.

0 0 00 0 _ g and ntercept_1 -« Te McroStaistcia isals thfist4and

__ &X >; ;; held statistical machine that's programmabl2e.'_ It allows you to have two 8~~~~~~~~~~~~~~~~~~~~~~~~0-se rgasiCompucorp

The Unknown Factor in 63 countries.;rrl. Rf 2oen R 2n rr' Sprvice Card

It's got a lot of icei little features...3,lectronic motor, quick-action eak,

uelecorshildx, stamiess-steerWhether you're simply evaporating or drying powders

waterbath). or working with very viscous materials, the BGchi/BrinkmannRotavapor-RE is probably the ideal rotating evaporatorfor your needs. Consider these important features: anelectronically-controlled motor that provides almost constanttorque over its entire range of speeds from 10 to 220 rpm.(Careful use of the speed control helps reduce foamingand bumping of liquids.) A deflector ring in the drive unitprotects gears from distillate in case of a faulty vacuum seal.

The entire evaporator unit can be raised or loweredeasily and safely by means of the quick-action jack. TheRotavapor-RE comes equipped with stainless-steel waterbath (accurate to ±-1.00C) and specially coated base casting.For freeze-drying operations, an optional cold trapcondenserjs available. For an illustrated brochure describing

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