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PARTNERING FOR
INNOVATION - Enriching
lives, shaping the future
MIDA SEMINAR ON CAPACITY
BUILDING FOR
PHARMACEUTICALS AND MEDICAL
DEVICES INDUSTRIES
7TH SEPTEMBER 2016
ROFINA YASMIN OTHMAN ASSOC VICE CHANCELLOR (INDUSTRY & COMMUNITY NETWORKS)
Malaysia’s first & top university
Ranked 3rd in South East Asia, 27th in Asia (QS Asia 2016), 146th in the World (QS 2015)
First university in Malaysia to be awarded QS 5-Stars (2014)
Only Malaysian university in ARWU 301-400 (2015)
Situated on a 812-acre campus in the southwest of Kuala Lumpur
Status: Research Intensive, Government Supported
Faculty: ~2,000 (~300 international)
Students ~23,000 (1:1 UG to PG, 3100 international)
>50 research centres, 6 Research Clusters
Malaysia’s largest (1,200 beds) & best teaching hospital
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Malaysia’s Best Research Univ 2015
QS Top 50 Ranked in 2 subjects QS Top 100 Ranked in 9 subjects
3,446 ISI-indexed papers
3,799 Scopus-indexed papers
8,147 Citations
2.14 Citations per paper
1.38 Field-weighted citation impact
130 Patents filed
28 Patents granted
2,049 Inbound Students
2,138 Outbound Students 3
Faculties
Medicine
Science
Engineering
Built Environment
Economics &
Administration
Business &
Accountancy
Education
Research Clusters
Wellness
Innovative Technology
Frontier Science
Equitable Society
Humanities
Sustainability Science
4
12 Faculties
2 Academies
4 Institutes
3 Academic
Centres
6 Research
Clusters
Broad-based Research-Intensive University
Sports Centre
Languages
& Linguistics
Law
Cultural Centre
Dentistry
Computer Science
& IT
Arts & Social
Sciences
Islamic Studies
Malay Studies
>100 undergrad programs >100 Masters programs 4 Doctoral programs
Institutes
Graduate
Studies
Asia-Europe
INPUMA
Educ Leadership
Centres
Foundation
Studies
Sports
Cultural
QS Top 50 Ranked in 2 subjects QS Top 100 Ranked in 9 subjects
Talent engagement –
invitation for industry to
register
• Student recruitment
• Practical training placements
• Strucutued internships
• Postgraduate placements and
recruitment
• Industry sponsored MSc/PhD
Bachelor in Pharmacy
(Honours)
Students undertake broad training in:
• physical and biological sciences;
• knowledge of drugs and their effects,
• the application of this knowledge to individuals;
• the ability to provide advice and pharmacy care to
consumers;
• and a scientific approach that will permit critical appraisal
of developments in pharmaceutical sciences.
4 years course
44 core pharmacy modules
One Stop Centre for
Pharmaceutical Research
• University of Malaya also offer Postgraduate programmes by research leading to MSc and PhD degrees.
• The research programmes encompass various areas of pharmaceutical sciences, including medicinal chemistry, natural products chemistry, drug action, drug delivery, and project related to clinical and pharmacy practice.
• The department is equipped with state-of-the-art research tools for biological chemistry, analytical chemistry and formulation research such as a pharmaceutical pilot plant facility for scale up experimental production of liquid and solid dosage forms and medium throughput biomolecular assays facility.
Faculty of medicine
Bsc (biomedical sciences) Parasitology, pharmacology,
Medical microbiology,clinical
chemistry
Faculty of science
BSc Microbiology, Biohealth,
Biochemistry, Chemistry
Faculty of engineering
B.Eng (biomedical engineering)
1.0 Million patients annually
Established in 1968
Statutory body under the Ministry of Education
Pioneer in Clinical Research & Teaching
Core activities – health services, teaching and research
FACILITIES AVAILABLE 1:
CLINICAL INVESTIGATION CENTRE
15
CLINICAL INVESTIGATION CENTRE
FACULTY OF MEDICINE | UNIVERSITY OF MALAYA
Focus facility 1: Clinical
Investigation Centre
Location
13th floor, Main Tower, 2nd floor RUKA building,
Oncology and Renal unit of UMMC
A dedicated unit for conducting clinical trials at
University Malaya Medical Centre (UMMC)
OBJECTIVES
To serve pharmaceutical and biotech companies in
providing a unique combination of academic
excellence and experience to expedite safe and
quality trials in Malaysia
To provide a carefully controlled research
environment, centered around patients, for doctors
and clinical scientists to conduct safe and high
quality clinical trials
OBJECTIVES
To ensure that all clinical trials are compliant with
the Malaysian and ICH Good Clinical Practice
Guidelines and observe current standards of
research ethics. CIC ensures that research
performed under its auspices is acceptable to
international regulatory authorities
To serve as a resource for apprenticeship for
young clinical investigators
Services
Point of contact to access an integrated network of
top performing clinical investigators
Feasibility surveys
Budget negotiation and Clinical Trial Agreement review
Access to UMMC’s large pool of potential research subjects
including healthy volunteers
CIC
Sponsor
Services CIC
PI
Dedicated & experienced study coordinators
Financial management & legal liaison
Provision of facilities to conduct trials
Conduct GCP training and updates
ACHIEVEMENTS
1. 2010:
Recognised by Quintiles, the world
largest CRO as the first prime site in Asia
for the conduct of clinical trials
ACHIEVEMENTS
2. May 2013: Awarded the Best Prime Site in
the world for Recruitment number at the
half-year mark of 2013 by Quintiles
4. July 2013: Awarded by Pfizer Inc as a site of INSPIRE
Program, the first in Malaysia
5. Jun 2014 : INSPIRE site for Pfizer
INSPIRE stands for Investigator Networks, Site Partnerships
and Infrastructure for Research Excellence are strategic set
of sites that are highly productive, medically relevant &
aligned to Pfizer’s business
FOCUS FACILITY 2:
ANIMAL EXPERIMENTAL UNIT (AEU)
ANIMAL EXPERIMENTAL UNIT (AEU)
FACULTY OF MEDICINE | UNIVERSITY OF MALAYA
26
The Animal Experimental Unit (AEU) of the Faculty of Medicine (FOM)
was established in 2012 and in 2014 became the first academic
institution in Malaysia to receive FULL AAALAC accreditation. FOM also
operates four satellite laboratories
FOM, UM
AEU
Rodents
Rabbits
SAF
Rodents
Parasitology
Pharmacology
Physiology
Zebrafish Biomedical
Sciences
ANIMAL EXPERIMENTAL UNIT (AEU)
FACULTY OF MEDICINE | UNIVERSITY OF MALAYA
FACILITIES
EQUIPMENT
Holding and Procedure Rooms Operating Theatre and Post Operative Recovery Room ABSL-2 Suite Specific Pathogen Free (SPF) Suite ZebraFish Laboratory
Open Cages – Rodent & Rabbit Individually Ventilated Cages (IVC) Cage Changing Station Biohazard Class II Safety Cabinet In–Vivo Imaging System
ANIMAL EXPERIMENTAL UNIT (AEU)
FACULTY OF MEDICINE | UNIVERSITY OF MALAYA
ANIMAL EXPERIMENTAL UNIT (AEU)
FACULTY OF MEDICINE | UNIVERSITY OF MALAYA
• Facility Induction Course Responsible Care Use and Laboratory Animal Course(RCULAC)
• Basic Rodent & Rabbit Handling • Veterinary Medical Care Training • AAALAC International Accreditation Consultancy • Basic Rodent & Rabbit Necropsy & Tissue Collection
Techniques
TRAININGS OFFERED
Training/consultations conducted to date: • Faculty of Medicine, Universitas Padjadjaran
Indone – Facility operation • USM – Facility Operation • Institute of Health Sciences, University of
Brunei Darussalam – MLT Training • IPHARM – Veterinary Medical Care Training • International Islamic University of Malaysia
(IIUM) – AAALAC • Sunway University – AAALAC • UPM - AAALAC
SUCCESS CASES
ANIMAL EXPERIMENTAL UNIT (AEU)
FACULTY OF MEDICINE | UNIVERSITY OF MALAYA
INFRA Laboratories are equipped with
advanced technology facilities with
excellent technical support to fulfil our
customers’ needs.
SERVICES & FACILITIES OFFERED
• Services consist of:
1. Sample Testing
2. Training & Workshop
3. Collaboration in R&D
CENTRES OF RESEARCH Focused, Multidisciplinary & Cross Faculty Centres – A selection from more than 50 centres on campus
GRAND CHALLENGE: ACTIVE AGEING
• Wellness Research Cluster (WRC) coordinates multi and
trans-disciplinary research activities that promote human
well-being and complementing the eight elements of
wellness;
• Currently, we are challenging researchers to demonstrate
new ways of thinking that go beyond traditional
frameworks and disciplines through a grand challenge
program- ACTIVE AGEING.
FOCUS:
CENTRE OF EXCELLENCE (COE)
TIDREC
45 TROPICAL INFECTIOUS DISEASES
RESEARCH & EDUCATION CENTRE
ONE-STOP RESEARCH
CENTRE FOR TROPICAL
INFECTIOUS DISEASES
• TIDREC was established in 2008
• Focal point for national and international collaborative
research for academic institutions and research industries
in Malaysia
• FIRST in country to install fully certified modular
Biosafety Level 2 & 3 Laboratories for research involving
virulent pathogens.
• ONLY centre operating a mock BSL 3 training facility
SERVICES OFFERED
• Virus detection and serotyping and serological assay
• Bacterial identification
• Antiviral Screening
• Biohazard Spill Kit
• Consultations and training modules on biosafety and biosecurity.
Centres for informatics
Centre for Medical informatics and biological microelectronics systems (CMMS)
• Innovative technology
cluster
• Faculty of Engineering
Centre of Research for Computational Sciences & Informatics for Biology, Bioindustry, Environment, Agriculture, and Healthcare (CRYSTAL)
• Frontier science cluster
• Faculty of Science
CENAR
Centre for Natural Products Research and Drug Discovery
• Dept of Chemistry, Faculty of Science
• Focus on multi-discipline research in natural
products and drug discovery
SERVICES OFFERED
Centre for Natural Products Research and Drug Discovery
• Plant identification
• Biological Screening (in-vivo and in-vitro)
• Analysis of plant active compounds
• Extraction methods for testing and commercialization
• Preparation of crude drug extract
• Standardization of products
• Consultancy in commercialization (biological and green
chemistry products)
• Extraction and isolation of active compounds
• X-ray structure determination and characterization
• Synthesis, semi-synthesis, heterocyclic and macrocyclic
synthesis
Some of Our Pool of Experts &
Expertise
• Prof. Dr. Adeeba binti Kamarulzaman
• Infectious/Communicable Diseases
• Prof. Dr. Mohd Rais bin Mustafa (Pharmacologist)
• Drug screening & bioassays, flavonoids, endothelial dysfunction
• Prof. Dr. Mustafa bin Ali Mohd (Pathologist)
• Endocrine disrupters, clinical pharmacology, drugs of abuse, traditional medicine, medicinal chemistry, xenobiotcs, toxicology
• Prof. Dr. Sazaly bin Abu Bakar (Medical Microbiologist)
• Virology, Baceteriology, Biorisk Management
• Prof. Dr. Lam Sau-kuen (Physiologist)
• Systems Physiology
INTELLECTUAL PROPERTY
PATENTS, COPYRIGHTS ETC
• LIST AVAILABLE
• FAST TRACK INDUDSTRY FRIENDLY LICENSING
• DEDICATED IP MANAGEMENT OFFICE
Rank Applicant No. of Applications
2014 2015
1 Universiti Malaya 164 129
2 Universiti Teknologi Malaysia 90 101
3 MIMOS Berhad 117 98
4 Universiti Putra Malaysia 49 46
5 Universiti Malaysia Sarawak 10 36
6 Majlis Amanah Rakyat (MARA) 18 34
7 Universiti Malaysia Pahang 20 31
8 Universiti Kebangsaan Malaysia 33 28
9 Malaysian Palm Oil Board (MPOB) 15 24
10 Universiti Sains Malaysia 14 22
Sumber : KASS IP
Industry on campus
• UM has created spaces for industry on campus and will
continue to open opportunities for strategic partnerships
• Industry laboratory spaces
• Incubator facilities
• Co-working spaces
• Access to facilities
• Industry faculty
.
UM Incubators
OFFICE PREMISE
LAB AND OFFICE
SHARED FACILITIES
INNOVATION SPACE/ SHOW
ROOM RECREATIONAL
MEETING SPACE
Current
incubator in
IPPP building
11 incubatees
2 partner tenants
Idea space
PERSPEKTIF DARI BELAKANG
Floor 4
• ICT accelerator and incubator
• MSC incubator status (Whole facility pending approval)
Floor3
• Diagnostic and Life science accelerator and incubator
• GLP and GMP pilot Floor2
• Physical science E&E incubators
• Gan-on Gan LED incubator (a CREST partner with UCSB)
Floor1
• Sub surface O&G incubator and services (an MPRC partner )
Co-incubation opportunites
under ASEAN USTART
Incubate
Launching November 2016 - UNIVERSITY INNOVATION INCUBATOR COMPLEX (I2U) UNIVERSITY OF MALAYA
Professionally managed full serviced incubator . Strategic tenancy focus
Provision of high end technology services to industry
Pharmauji Sdn Bhd in partnership with
Develop a world–class program to
• a) bring out licensable pharmaceutical drug candidates for
commercialization eventually by pharma companies;
• (b) establish a world-class biotech business environment in Malaysia, in
partnership with international partners
• (c) train and develop biotech 50-60 Scientists, drawn from University of
Malaya or other institutions of higher learning in Malaysia, and industry in
Malaysia
Tech focus
“MEDCOM
CENTRAL"
Modular work flow management
system for Surgeons and Hospital
Managers
Accessible through Mobile devices • Real Telemedicine
• Integration, storage of transmission digital visual data and other operating room data generated
• Based on off the shelf tech integrated utilising proprietary soft ware
• Independence from proprietary devices providers
• Expandeble to other critical areas of hospital and beyond.
• Developed by Surgeons
TECH
focus
“3D
Biomodel
Printing”
https://3dprint.com/tag/university-of-malayas-
centre-for-biomedical-and-technology-
integration-cbmti/
Tech focus
“DOSIMETER“
Innovative types of optical
fiber based dosimeters
Flexible in design and
manufacturing
10x higher resolution
compared to commercial alt.
Water resistance
Immune to electromagnetic
interference
– Prof. Faisal Rafiq Mahamd Adikan
DrGhafor Amouzad Mahdiraji
Winner of Rice Bowl Awards Best ASEAN University Start-up 2015
Winner of Newton-Ungku Omar Fund Dengue Tech Challenge 2016
SENSOR FOR REAL-
TIME DOSE
MONITORING
UNLOCKING
NEW
PARTNERSHIPS
• Growing portfolio of IPR presents opportunities for Malaysia industry
• Increasing demand from international market
• Would like to accelerate transfer of technologies to industry as solution provider
• Partnerships for “first in market” proof of concept in Malaysia
• Looking to have more partners for codevelopment/test bedding/marketing/coproducing/ uptake technologies
• Would like to invite more venture funding/investment/licensing partners
ENGAGE -CONNECT! THE FUTURE IS TOGETHER
Email us : [email protected]
Call us: 03-79677352 Dr Yusrizam/Wan Afna/Nasrul
Visit us: Level 5, IPPP complex, University of Malaya