Pathology of cancer

of Paranasal sinuses

M N El-Bolkainy

NCI, Cairo University

2009

Classification

• PRIMARY TUMORS

1.Epithelial

2.Neuroectodermal

3.Mesenchymal

• SECONDARY TUMORS

1.Local spread

2.Metastatic

Epithelial tumors

1. Schneiderian origin

2. Minor salivary origin

3. Odontogenic origin

Inverted papilloma

Transitional carcinoma

Squamous carcinoma

Verrucous carcinoma

Papilary squamous carcinoma

Basaloid carcinoma

Undifferentiated carcinoma

Adenocarcinoma

Adenuid cystic carcinoma

Ameloblastoma

Neuroectodermal tumors

1. Olfactory neuroblasoma (Central PNET)

2. Malignant melanoma

3. Ectopic meningioma

Olfactory neuroblasoma

Melanoma

Ectopic meningioma

Mesenchymal tumors

1. Soft tissue • Low Malignant Potential (LMP)

• Malignant

2. Bone sarcomas

3. Lymphomas

Myxoma

Giant cell lesion

Angiofibroma

Rhabdomyosarcoma (RMS)

RMS

RMS

Chondrosarcoma Osteosarcoma

Chordoma

Burkitt

NHL

T/NK cell lymphoma

Secondary tumors

1. Local invasion from: Nasal cavity, nasopharynx and orbit

2. Metastatic from: kidney is the most common primary

Clear cell carcinoma