pathology of pneumonia
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Pathology of Pathology of PneumoniaPneumonia
Dr. Venkatesh M. ShashidharDr. Venkatesh M. ShashidharSenior Lecturer in PathologySenior Lecturer in PathologyFiji School of MedicineFiji School of Medicine
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Introduction:
Daily 10,000 liters of air - filtered..! Pneumonia: Inflammation of lung. Respiratory tract infections –
commonest in medical practice. Enormous morbidity & mortality.
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Etiology: Decreased resistance - General/immune Virulent infection - Lobar pneumonia Clearing mechanism
Cough Reflex Mucosal Injury Low Alveolar defense Pulmonary edema Obstructions
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Types: Viral Bacterial Mycoplasmal Fungal
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Patterns of Pulmonary infections:
Airway - Bronchitis, Bronchiectasis Parenchyma
Pneumonia BronchopneumoniaLobar pneumonia
Lung abscessTuberculosis
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Bronchopneumonia Staph, Strep, Pneumo & H. influenza Patchy consolidation – not limited to lobes. Suppurative inflammation Usually bilateral Lower lobes common Complications:
Abscess Empyema Dissemination
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Broncho-pneumonia
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Broncho-pneumonia
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Broncho-pneumonia
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Bronchopneumonia - Abscess formation
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Bronchopneumonia:
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Bronchopneumonia:
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Bronchopneumonia - Abscess formation
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Lung RSV Pneumonia:
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Bronchopneumonia - CT
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Bronchopneumonia - CT
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Lobar Pneumonia: Fibrinosuppurative consolidation – whole lobe Rare due to antibiotic treatment. ~95% - Strep pneumoniae types 1,3,7& 2. Four stages:
Congestion. Red Hepatization. Gray Hepatizaiton. Resolution.
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Lobar Pneumonia:
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Lobar Pneumonia – Gray hep…
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Lung Abscess: Focal suppuration with necrosis of lung tissue Strep, Staph & Gram negative & anaerobes Mechanism:
Aspiration Post pneumonic Septic embolism Neoplasms
Productive Cough, fever. Clubbing Complications: Systemic spread, septicemia.
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Lung Abscess:
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Lung Abscess:
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Lung Abscess - Chronic:
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Lung Fungal Abscess: Candida
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Normal Lung
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Normal Lung
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