° Ergonomic styling and intuitive software design

° Verifiable accuracy across a wide flow range and environmental conditions

° Simple check for accuracy with easy calibration, if necessary

° Large variety of predicted equations, including GLI

° Photo-realistic incentive graphics

° Real-time flow/volume and volume/time curves

° FVC, SVC, MVV, Pre/Post Bronchodilator, and Challenge testing

° Comprehensive, customizable reporting capabilities

° 32- or 64-bit Windows 7, 8, 8.1, & 10 support

° Lifetime sensor lowers costs

° Industry-proven reliability with an uptime guarantee and performance assurance over the life of the device

KoKo Sx Network Edition enables workflow management

° Collect more types of data in one location (including questionnaires)

° Automate transmission of visit data to the next step in your workflow

° Securely share data across rooms or clinics

With decades of pace-setting performance, KoKo® Sx 1000’s easy-to-use, advanced technology provides secure, dependable, and consistent results for faster, more confident interpretations all with the lowest total cost of ownership.

INDUSTRY LEADING SPIROMETRY PERFORMANCE WITH NEW STYLING, WORKFLOW MANAGEMENT, AND SEAMLESS INTEROPERABILITY WITH YOUR EMR

Sx 1000PC-Based Diagnostic Spirometer

CLINICALLY-PROVEN ACCURACY AND RELIABILITY The spirometer internal medicine physicians trust most with over 50 Million tests performed, KoKo Sx 1000 compensates for environmental variances and is highly accurate even at low flow rates. Independently validated to exceed published guidelines, KoKo Sx 1000 delivers consistent results with the lowest breathing resistance to minimize impact on patients with severe respiratory disease.

INNOVATIVE TECHNOLOGY FROM THE SPIROMETRY EXPERTS

INTUITIVE SOFTWARE KoKo Sx software blends sophisticated features with a friendly, intuitive user interface. Built-in quality checks ensure accuracy and reproducibility, requiring fewer efforts to get usable results.

TARGET-ADJUSTED, INCENTIVE GRAPHICS Make spirometry testing more exciting while improving patient compliance. Incentive target values are automatically adjusted based on patient ability, increasing test performance in pediatric patients.

EXTENSIVE, FLEXIBLE REPORTING Featuring a wide variety of reporting, predicted equation, and automated interpretation options, KoKo Sx provides industry leading performance, configurability, and versatility. A large selection of comprehensive report designs, including trends and challenge,can be customized with the built-in report designer.

LOWEST LIFECYCLE COST Lifetime flow sensors reduce replacement and recalibration costs, inexpensive anti-bacterial filters reduce the cost of operation, and bundled services with software updates and upgrades lead to the lowest cost per test over the life of the device.

elliptical & standard filters

DEDICATED PHYSICIAN AND PRACTICE MANAGEMENT WORKSTATIONS

° Easily review and interpret patient test data based on the complete picture, including patient reported data and priors, and generate final reports at a workstation designed specifically for physicians. Associating interpretations directly with the report before sending along to the EMR ensures your findings are viewed in context by other stakeholders.

° Quickly review practice quality, productivity, and related measures.

NETWORKING SOLUTIONS FOR COLLABORATIVE CARE

Beyond patient testing, improving patient care requires streamlined data management and access for all stakeholders.

ELECTRONIC QUESTIONNAIRES (EFORMS) Quickly collect patient reported data, including symptom scores and quality of life information, using electronic questionnaires. Once completed, these eForms are attached to your patient’s test data throughout the visit workflow. Each eForm is clinically designed based on disease state, providing more relevant data during test interpretation and for ongoing disease management.

SHARE AND ACCESS DATA ANYWHERE Automatically send PFT reports and relevant respiratory data (including eForms) to the next step in your workflow and securely share data with all stakeholders, between clinics or across the room, without the need for a common EMR or HIS system.

Required for Networking • KoKo Sx 1000 Spirometer Network Edition - includes pnuemotach, testing software, & filter samples • Iris SQL Database - central administration, data redundancy & backup

Other Optional Networking Solutionsh Testing software (additional copy of KoKo Sx Testing Software Network Edition) - to improve productivity while lowering your costs

Dedicated Physician Review Stationsh Basic (KoKo Sx) - electronic review with automated interpretationh Web-based (Iris Inform) - electronic review, automated interpretation, digital signature with batch sign & sendh Full-featured (Iris Decision) - electronic review, automated interpretation, digital signature, access to home spirometry data & quality reports

EMR Connectivityh HL7 interface engine (Iris Connect)

nspirehealth.com+1.303.666.5555 or 800.573.7374 (USA) +44 (0) 1992 526300 (UK) +49 (0) 9736 8181 0 (Germany)1830 Lefthand Circle, Longmont, CO 80501

STREAMLINED EMR CONNECTIVITY Based on a powerful standards-based HL7 interface engine, KoKo Sx Network Edition and Iris Connect work together with any HL7 compliant EMR system to ensure seamless transmission of patient orders and test results without any third party licensing fees.

*See nspirehealth.com/iris-connect for an up-to-date list of certified vendors with standard templates, and other vendors with field configurable HL7 compliant interfaces.*Custom results (discrete parameters) are available through nSpire Health’s professional services offerings.

PN: 633201.A

ABOUT NSPIRE HEALTHnSpire Health is a global respiratory information systems software developer and medical device manufacturing company. We are the exclusive provider and developer of Iris™, the world’s first Integrated Respiratory Information System, and KoKo® pulmonary function, diagnostic spirometry, and respiratory home monitoring devices. Together, our expert scalable software solutions and sophisticated data collection products empower healthcare providers to advance respiratory diagnostic processes and improve patient outcomes, while meeting the demanding clinical and business objectives of thought leaders in respiratory care.

©2016 nSpire Health. All rights reserved. nSpire Health is a trademark and KoKo is a registered trademark of nSpire Health, Inc. All other trademarks and tradenames are the property of their respective holders.

PERFORMANCE SPECIFICATIONSTests Performed Forced Vital Capacity, Slow Vital Capacity, Pre- and Post- Bronchodilator, Maximum Voluntary Ventilation, ChallengeParameters Measured Expiratory (in FVC test): FVC, FEV.5, FEV.5/FVC%, FEV1, FEV1/FVC%, FEV3, FEV3/FVC%, FEV6, FEV6/FVC%, FEV1/FEV6%, PEFR, FEF25%, FEF50%, FEF75%, FEF25-75%, FEF.2-1.2, FEF75-85%, Tpeak(ms), Vext%, Vext(l), MET(s), Texp(s), Veot(l)Inspiratory FIVC, FIV.5, FIV.5/FIVC, FIV1/FIVC, FIV3, FIV3/FIVC, PIFR, FIF50%, FIF25-75%, FIF.2-1.2, FIF50/FEF50, MIT(s), Tinsp(s)Accuracy <+3% or 100 ml, whichever is greater; research grade accuracy of <1% can be set via calibrationReproducibility <+0.5% or 0.150 l whichever is greaterVolume Range +16 l Flow Range +16 l/s Resistance <1.5 cmH2O/l/s when tested with KoKo Moe filterReports Unlimited, multiple preset designsIncentive Graphics Candles, butterfly, cake, sailboat, brickwall, carnival game, lungs, kite Interpretation Algorithm McKay (ATS / ARRD 1991); ITS; Modified Ellis Predicted Sets Quanjer GLI 2012 (Global), Crapo 1981, Polgar (Pediatrics), ITS 1984, Knudson 1976/1983, ECCS 1983/1993, Hankinson (NHANES III) 2000, Toronto 1991, Morris F 1988/1971, Gore (Australia) 1995, Pereira (Brazil) 1996, Dejsomritrutai (Thai)1996, Miller 1996, Eigen (pre-school pediatrics), Viljanen/KLNW (Finland), Hendenstrom/Solymar (Sweden), Gulsvik (Norway), SEPAR (Spain), Forche (Austria), Hibbert (Pediatrics), Shands (mixed), Wang (Pediatrics), Pereira (Brazil), Knudson 1976

Minimum Computer RequirementsKoKo Sx 1000 Standalone Edition: Windows 7, 8, 8.1, & 10; 32- & 64-bit, 1 GHz processor, 1 GB memory minimum, USB port for pneumotach KoKo Sx 1000 Network Edition: Windows 7, 8, 8.1, & 10; 32- & 64-bit, 2 GHz processor, 2 GB memory minimum, USB port for pneumotach, internet/intranet access to central database via wifi or wired connectionPhysical SpecificationsHeight 7.1 in (18 cm)Width 3.9 in (10 cm)Depth 2 in (5 cm)Weight 0.7 lbs (0.3 kg)Material High-impact PolycarbonatePneumotachometer Brass Core FleischPower Requirement USB portFilter Requirement KoKo filtersCalibration 3 Liter Syringe (3 injection mode)Environmental SpecificationsOperating temperature 10 - 40 degrees COperating humidity - 80% relative humidity non- condensing at temperatures to 31 degrees CStandards & Regulation ConformanceIndustry Guidelines ATS/ERS 2005 Quality System Regulations FDA QSR, ISO 13485 (CMDCAS, MDD)Product Testing Standards IEC/EN 60601-1, 60601-1-2, 60601-1-6, ISO 26782European Directives MDD 93/42/EEC, RoHS 2011/65/EU

Sx

° Allscripts™

° athenahealth®

° Cerner®

° Epic®

° GE® Centricity™

° McKesson®

° MedFormix®

° Meditab® IMS™

° Meditech®

° ModuleMD™

° NextGen®

° Others*