The WHO Recommended Classification of Pesticides by Hazardand

Guidelines to Classification 2009

WHO Library Cataloguing-in-Publication Data

World Health Organization.

The WHO recommended classification of pesticides by hazard and guidelinesto classification: 2009.

1. Pesticides – toxicity. 2. Pesticides – classification. 3. Hazardous substances – classification. 4. Guidelines. I. International Programme on Chemical Safety. II. Title.

ISBN 978 92 4 154796 3 (NLM classification: WA 240)ISSN 1684-1042

© World Health Organization 2010

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1

THE WHO RECOMMENDED CLASSIFICATION OF PESTICIDES BY HAZARD AND GUIDELINES TO CLASSIFICATION 2009

The WHO Recommended Classification of Pesticides by Hazard was approved by the 28th World Health Assembly in 1975 and has since gained wide acceptance. When it was published in the WHO Chronicle, 29, 397-401 (1975), an annex, which was not part of the Classification, illustrated its use by listing examples of classification of some pesticidal active ingredients and their formulations. Later suggestions were made by Member States and pesticide registration authorities that further guidance should be given on the classification of individual pesticides. Guidelines were first issued in 1978, and have since been revised and reissued every few years.

Up until the present revision the original guidelines approved by the World Health Assembly in 1975 have been followed without amendment. In December, 2002 the United Nations Committee of Experts on the Transport of Dangerous Goods and on the Globally Harmonized System of Classification and Labelling of Chemicals (UNCETDG/GHS) approved a document called “The Globally Harmonized System of Classification and Labelling of Chemicals” with the intent to provide a globally-harmonized system1 (GHS) to address classification of chemicals, labels, and safety data sheets. The GHS (with subsequent revisions) is now being widely used for the classification and labeling of chemicals worldwide. For this revision of the Classification the WHO Hazard Classes have been aligned in an appropriate way with the GHS Acute Toxicity Hazard Categories for acute oral or dermal toxicity as the starting point for allocating pesticides to a WHO Hazard Class (with adjustments for individual pesticides where required). It is anticipated that few of the more toxic pesticides will change WHO Hazard Class as a result of this change. As has always been the case, the classification of some pesticides has been adjusted to take account of severe hazards to health other than acute toxicity (as described in Part II). The GHS Acute Toxicity Hazard Category for each pesticide is now presented alongside the existing information.

The document is arranged as follows:

Part I: Overarching principles for the classification of pesticides as recommended by the World Health Assembly. These principles continue to apply, but the World Health Assembly Resolution envisaged that the classification criteria might need to be developed with time and increasing experience. The guide-points originally proposed in 1975 are now being aligned with the corresponding Acute Toxicity Hazard Categories from the GHS.

Part II: Guidelines to Classification. Individual products are classified in a series of tables, according to the oral or dermal toxicity of the technical product. The tables are subject to review periodically.

The toxicity values are intended to be a guide only. Formulations should be separately classified using the methods set out on pages 4 (single technical product) and 7 (mixtures) and the table in Part I. To assist in the classification of formulations, an annex is provided giving numerical tables from which the classification may also be derived.

1 See http://www.unece.org/trans/danger/publi/ghs/ghs_rev03/03files_e.html.

2

Comments on Part II of the document are welcome, together with proposals for new entries. These should be addressed to the International Programme on Chemical Safety, World Health Organization, 1211 Geneva 27, Switzerland, and should include supporting data on the compound being commented on or proposed.

This document is a revision of the document previously issued as ISBN 92 4 154663 8.

3

PART I RECOMMENDED CLASSIFICATION OF PESTICIDES BY HAZARD

Extract from WHO Chronicle, 29: 397-401 (1975)In 1973, the WHO Executive Board asked the Director-General of WHO to take steps to develop a tentative classification of pesticides that would distinguish between the more and the less hazardous forms of each pesticide. A proposal for a WHO recommended classification of pesticides by hazard was accordingly prepared, taking into account the views of members of the WHO Expert Advisory Panel on Insecticides and other expert advisory panels with special competence and interest in pesticide technology, as well as the comments of WHO Member States and of two international agencies. This proposal was adopted by the Twenty-eighth World Health Assembly, which recommended the use of the classification by Member States, international agencies, and regional bodies.

The text below is reproduced from the Proposal2 which was adopted by the World Health Assembly in 1975.The hazard referred to in this Recommendation is the acute risk to health (that is, the risk of single or multiple exposures over a relatively short period of time) that might be encountered accidentally by any person handling the product in accordance with the directions for handling by the manufacturer or in accordance with the rules laid down for storage and transportation by competent international bodies.

Any classification based on biological data can never be treated as final. In the assessment of biological data, honest differences of opinion are inevitable and most borderline cases can be reclassified in an adjacent class. Variability or inconsistency in toxicity data due to differences in susceptibility of test animals, or to experimental techniques and materials used can also result in differing assessments. The classification criteria are guide-points intended to supplement but never to substitute for special knowledge, sound clinical judgement or experience with a compound. Reappraisal might be necessary from time to time.

Basis of classification

The classification distinguishes between the more and the less hazardous forms of each pesticide in that it is based on the toxicity of the technical compound and on its formulations. [In particular, allowance is made for the lesser hazards from solids as compared with liquids.]3

The classification is based primarily on the acute oral and dermal toxicity to the rat since these determinations are standard procedures in toxicology. Where the dermal LD50

4 value of a compound is such that it would place it in a more restrictive class than the oral LD50 value would indicate, the compound will always be classified in the more restrictive class. Provision is made for the classification of a particular compound to be adjusted if, for any reason, the acute hazard to man differs from that indicated by LD50 assessments alone.

2 Official Record of the World Health Organization 1975, No.223, Part 1, p.123 Note:- this distinction is not made in the GHS and no longer applies to the WHO Classification4 The LD50 value is a statistical estimate of the number of mg of toxicant per kg of bodyweight required to kill

50% of a large population of test animals.

4

Application of the criteria for classification

(a) Where it is shown that for a particular compound the rat is not the most suitable test animal (for example, if another species is conspicuously more sensitive or more closely resembles man in its reaction) then the classification of that compound should take this into account.

(b) In practice, the majority of classifications will be made on the acute oral LD50 value. However, dermal toxicity must always be considered since it has been found that, under most conditions of handling pesticides, a high proportion of the total exposure is dermal. Classification based on dermal data in a class indicating a great risk is necessary when the dermal LD50 values indicate greater hazard than oral LD50 values.

(c) If the active ingredient produces irreversible damage to vital organs, is highly volatile, is markedly cumulative in its effect, or is found after direct observations to be particularly hazardous or significantly allergenic to man, then adjustments to the classification can be made by classifying the compound in a class indicating a higher hazard. Alternatively, if it can be shown that the preparation is less toxic or hazardous than expected from consideration of the LD50 values of the ingredient or ingredients, or for any other reason, adjustments should be made by classifying the compound in a class indicating a lower hazard.

(d) In certain special cases the acute oral or dermal LD50 values of the compound or formulation should not be used as the main basis for classification. In such cases (for example, aerosol preparations, other special formulations and fumigants), more appropriate criteria should be used.

(e) It is highly desirable that, whenever practicable, toxicological data for each formulation to be classified should be available from the manufacturer. However, if such data are not obtainable, then the classification may be based on proportionate calculations from the LD50 values of the technical ingredient or ingredients, according to the following formula:

LD50 active ingredient×100Percentage of active ingredient in formulation

If the formulation contains more than one ingredient (including solvents, wetting agents, etc.) of significant toxicity-enhancing properties, then the classification should correspond to the toxicity of the mixed ingredients.

(f) With a few exceptions, pesticides have low volatility and therefore no criteria are at present set out for volatility in this Recommendation. The inclusion of such criteria is unlikely to affect the classification of pesticides by hazard except in the case of volatile fumigants used in agriculture and food storage. On the other hand, when the criteria are applied to pesticide formulations based on solvents or to other chemicals, account must be taken of volatility and consequent inhalation toxicity.

5

Effects of classification on labeling5

While no specific symbols to identify classes are included in the Recommendation, the following are the general implications of the classification as regards labelling.

The aim should be uniformity in the statement on the nature of the risk (by phrase and/or symbol) on the label of the product, irrespective of the country of origin or use. Labels of products classified in classes Ia and Ib should bear a symbol indicating a high degree of hazard (usually a type of skull and crossbones) and a signal word or phrase, e.g. POISON or TOXIC. The presentation of the symbol and word or phrase, in terms of colour, size and shape should ensure that they are given sufficient prominence on the label.

The text should be in the local language and for all formulations should include the approved name of the active ingredient or ingredients, the method of use, and precautions to be taken in use. For classes Ia and Ib, symptoms and immediate treatment of poisoning should also be included.

The detailed precautions necessary for the use of a pesticide depend on the nature of the formulation and the pattern of use and are best decided by a pesticide registration authority when accepting a commercial label.

There are international agreements on symbols to denote hazards from materials which are inflammable, corrosive, explosive, etc., and these should be consulted and used where appropriate.

Revised criteria for classification (introduced for 2009 update)The table showing the Recommended Criteria for Classification from the original World Health Assembly Proposal is not shown because it is no longer used. WHO now uses the Acute Toxicity Hazard Categories from the GHS6 as the starting point for classification. This change is consistent with the 1975 World Health Assembly Resolution which envisaged that the WHO Classification would be further developed with time in consultation with countries, international agencies and regional bodies. The GHS meets this requirement as a classification system with global acceptance following extensive international consultation.

WHO Class LD50 for the rat(mg/kg body weight)

Oral Dermal

Ia Extremely hazardous < 5 < 50Ib Highly hazardous 5–50 50–200II Moderately hazardous 50–2000 200–2000III Slightly hazardous Over 2000 Over 2000U Unlikely to present acute hazard 5000 or higher

Details of how the WHO Classification has been aligned with the GHS Acute Toxicity Hazard Categories are presented in Part II.

5 See International Code of Conduct on the Distribution and Use of Pesticides, FAO (2003), available at http://www.fao.org/docrep/005/Y4544E/y4544e00.HTM; also Guidelines on Good Labelling Practice for Pesticides, FAO (1995), available at http://www.fao.org/ag/AGP/AGPP/Pesticid/Code/Download/label.pdf

6 See http://www.unece.org/trans/danger/publi/ghs/ghs_rev03/03files_e.html. The categories for oral and dermal routes are used.

6

PART II GUIDELINES TO CLASSIFICATION OF PESTICIDES BY HAZARD

The main section of the guidelines consists of five tables preceded by notes on their use. In the tables, active ingredients (technical grade) have been classified as follows:

Table 1 EXTREMELY HAZARDOUS (Class Ia) active ingredients (technical grade) of pesticides .............................................................................................................. 19

Table 2 HIGHLY HAZARDOUS (Class Ib) active ingredients (technical grade) of pesticides .............................................................................................................. 21

Table 3 MODERATELY HAZARDOUS (Class II) active ingredients (technical grade) of pesticides .................................................................................. 24

Table 4 SLIGHTLY HAZARDOUS (Class III) active ingredients (technical grade) of pesticides .............................................................................................................. 34

Table 5 Active ingredients unlikely to present acute hazard in normal use ......................... 39

The tables are arranged in alphabetical order.

In addition, the following tables show the details stated:

Table 6 Active ingredients not included in the Classification and believed to be obsolete or discontinued for use as pesticides ........................................................ 47

Table 7 Pesticides subject to the prior informed consent (PIC) procedure .......................... 51

Table 8 List of gaseous or volatile fumigants not classified under the WHO- Recommended classification of pesticides by hazard ............................................. 53

ANNEX How to find the hazard class of a formulation ......................................................... 54

INDEX by CAS number ........................................................................................................ 57

by name of active ingredient .................................................................................... 65

7

NOTES ON THE USE OF THE TABLES IN CLASSIFICATION

The final classification of any product is intended to be by formulationThe classification given in the tables below is of active ingredients, and only forms the starting point for the final classification of an actual formulation. It is by far preferable that the final classification of a formulation should be based on toxicity data obtained on that formulation by the manufacturer: the criteria set out in the table of the Classification in Part I are then applied to this first-hand data. Only if this is not available should the formula be used, as shown in Part I on page 4 to extrapolate the LD50 of the formulation from that of the technical product. In this event, the single oral or dermal value of the LD50 given in the tables below should be used in the formula. See also the Annex on page 54.

The following important points should be noted.

1. While the classification deals only with the acute risk to health, evaluations of other effects, including cancer, have been completed for many compounds for registration purposes. Where other effects have been shown to occur in man, these are noted in the ‘Remarks’ column and may have in some cases resulted in an adjusted classification.

2. Wherever possible, the data are listed under internationally approved common names, or if such names are not at present available, under nationally approved names. Some other common names appear in the alphabetic index pp. 65-78. Trade names are not given since there are many of these.

3. A list of references that may be used for the identification of pesticides is given at the end of these introductory notes, and the manufacturer should always assist by specifying any existing approved or common names for his product.

4. It is not possible to include classification of mixtures of pesticides in the guidelines: very many of these are marketed with varying concentrations of active constituents. There are three possible approaches to the classification of mixtures - in order of preference:

(a) require the formulator to obtain reliable acute oral and dermal toxicity data for rats on the actual mixture as marketed: or

(b) classify the formulation according to the most hazardous constituent of the mixture as if that constituent was present in the same concentration as the total concentration of all active constituents: or

(c) apply the formula:

CT

CT

CT T

a

a

b

b

z

z m

+ + ≡… 100

Where C = the % concentrations of constituent A, B ... Z in the mixture T = the oral LD50 values of constituents A, B ...Z Tm = the oral LD50 value of the mixture.

The formula can also be used for dermal toxicities provided that this information is available on the same species for all constituents. The use of this formula does not take into account any potentiation or protective phenomena.

8

5. In the tables below, single figures have been given as LD50 values for classification purposes, using the route as described in the table. Where several LD50 values have been published, the lowest deemed reliable is used. Where a sex difference occurs in LD50 values, the value for the more sensitive sex is used. A number of adjustments to Classification have been made in respect of some pesticides and these are explained. A borderline case has been classified in the more or less hazardous class after consideration of its toxicology and use experience.

6. In the former WHO Classification scheme pesticides were classified on the basis of the physical state of the technical product. A distinction between liquids and solids is no longer made.

7. In Table 5, a number of pesticides are listed as unlikely to present any acute hazard in normal use. The WHO classification is open-ended but it is clear that there must be a point at which the acute hazard posed by the use of these compounds is so low as to be negligible provided that the precautions are taken that should be used in dealing with any chemical. In compiling this table, it has been assumed that this point is an LD50 of 5000 mg/kg bw or greater (in line with the upper limit for classification in the GHS). However, it should not be overlooked that in formulations of these technical products, solvents or vehicles may present a greater hazard than the actual pesticide and therefore classification of a formulation in one of the higher hazard classes may be necessary.

8. The WHO Classification is not limited to chemical pesticides. Biological pesticides can also be included if a suitable evaluation is available (Bacillus thuringiensis is included based on Environmental Health Criteria Document 217).

9. The toxicity data for pyrethroids is highly variable according to isomer ratios, the vehicle used for oral administration, and the husbandry of the test animals e.g. fasting prior to dosing. The variability is reflected in the prefix ‘c’ before LD50 values. The single LD50 value chosen for classification purposes is generally based on administration in corn oil and can be much lower than that in aqueous solutions. This underlines the need for classification by formulation if the classification is to reflect true hazard.

ENTRIES AND ABBREVIATIONS USED IN THE TABLES

New information since the previous edition is indicated by italics.

Column 1: Common name. [ISO] denotes common name of the active ingredient approved by the International Organization for Standardization. Such names are, when available, preferred by WHO to all other common names. However, attention is drawn to the fact that some of these names may not be acceptable for national use in some countries. If the letters ISO appear within parentheses (ISO), this indicates that ISO has standardized (or is in the process of standardizing) the name of the base, but not the name of the derivative listed in column 1. For example, fentin acetate (ISO) indicates that fentin is an ISO name, but fentin acetate is not. ISO* denotes pending ISO approval of the name. C denotes chemical, trivial, or other common name.

Column 2: CAS Registry number: The number for the chemical, not those for e.g. different esters or salts are given.

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Column 3: UN number refers to the UN Recommendations on the transport of dangerous goods, Eleventh revision (1999). This is given only for active ingredients in Tables 1, 2, 3 or 4, since so few ingredients in Table 5 have UN numbers. The UN number refers only to the active ingredient; formulations are likely to have different numbers, since the ingredient may, for example, be dissolved in a solvent - and liquid products have different UN numbers, which depends on their flammability.

Column 4: Chemical type. Only a limited number of chemical types are shown. Most have some significance in the sense that they may have a common antidote, or may be confused in the nomenclature with other chemical types e.g. thiocarbamates are not cholinesterase inhibitors and do not have the same effects as carbamates. Chemical type is also a determinant of the UN numbering system. These chemical classifications are included only for convenience, and do not represent a recommendation on the part of the World Health Organization as to the way in which the pesticides should be classified. It should, furthermore, be understood that some pesticides may fall into more than one type.

AS Arsenic compound OP Organophosphorus compoundBP Bipyridylium derivative OT Organotin compoundC Carbamate PAA Phenoxyacetic acid derivativeCO Coumarin derivative PZ PyrazoleCU Copper compound PY PyrethroidHG Mercury compound T Triazine derivativeNP Nitrophenol derivative TC ThiocarbamateOC Organochlorine compound

Column 5: Physical state. Refers only to the active ingredient. L denotes liquid, including solids with a melting point below 50oC; oil denotes oily liquids and S solids, including waxes. The physical state may affect the exposure potential, and thus the absorbed amount of the chemical, and was taken into account when determining classification under the previous scheme.

Column 6: Main use. In most cases only a single use is given. This is only for identification purposes and does not exclude other uses.

AC acaricide L larvicideAP aphicide M molluscicideB bacteriostat (soil) MT miticideFM fumigant N nematocideF fungicide, other than for seed O other use for plant pathogens treatment PGR plant growth regulatorFST fungicide, for seed treatment R rodenticideH herbicide RP( ) repellant (species)I insecticide -S applied to soil: not used with herbicides IGR insect growth regulator or plant growth regulatorsIx ixodicide (for tick control) SY synergist

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Column 7: GHS: This column indicates the classification of the pesticide according to “The Globally Harmonized System of Classification and Labelling of Chemicals” (GHS)7. The value shown in the column is the Acute Toxic Hazard Category according to the GHS criteria, which in turn is derived from the acute toxicity estimate value for the substance. In the majority of cases the acute toxicity estimate will be the experimentally-derived LD50 value for oral exposure. A comparison of the criteria (as LD50 values) used for the different classes in the former WHO Scheme or for GHS categories is shown in the tables below. The GHS table shows only a simplified summary; for full details of classification according to GHS the official publication of the GHS should be consulted.

Former WHO Classification Scheme

Class LD50 for the rat (mg/kg body weight)

Oral DermalSolids Liquids Solids Liquids

Ia Extremely hazardous 5 or less 20 or less 10 or less 40 or lessIb Highly hazardous 5 - 50 20 - 200 10-100 40 – 400II Moderately hazardous 50 - 500 200 - 2000 100-1000 400 – 4000III Slightly hazardous Over 500 Over 2000 Over 1000 Over 4000

GHS Classification

GHS Category Classification criteria

Oral DermalLD50

a

(mg/kg bw)Hazard

StatementLD50

b

(mg/kg bw)Hazard Statement

Category 1 < 5 Fatal if swallowed < 50 Fatal in contact

with skin

Category 2 5 - 50 Fatal if swallowed 50 - 200 Fatal in contact

with skin

Category 3 50 - 300 Toxic if swallowed 200 - 1000 Toxic in contact

with skin

Category 4 300 - 2000 Harmful if swallowed 1000 - 2000 Harmful in contact

with skin

Category 5 2000 - 5000 May be harmful if swallowed 2000 - 5000 May be harmful in

contact with skina For oral data the rat is the preferred species, though data from other species may be appropriate when

scientifically justifiedb For dermal data the rat or rabbit are the preferred species, though data from other species may be appropriate

when scientifically justified

7 See http://www.unece.org/trans/danger/publi/ghs/ghs_rev03/03files_e.html. The categories for oral and dermal routes are used

11

The former WHO Classification scheme applied different criteria to liquids and solids, but the GHS does not make a similar distinction and applies the same criteria. The GHS cut-off values for Category 2 and Category 3 are lower than the values which applied to liquids under the former WHO scheme, such that some liquids allocated to Class Ib would be placed in the lower GHS Category 3 (specifically pesticides with oral LD50 values in the range 50-200 mg/kg bw). In aligning the WHO scheme with the GHS criteria there was no intention to “lower” the classification of pesticides previously considered to be “Highly hazardous”. Therefore, the classification of this limited number of liquid pesticides has been adjusted such that they remain in Class Ib. The revised criteria for the WHO classification scheme are shown in Part I (page 5).

Column 8: LD50. The LD50 value is a statistical estimate of the number of mg of toxicant per kg of body weight required to kill 50% of a large population of test animals: the rat is used unless otherwise stated. Usually a single value, but sometimes a range is given. “c” preceding the value indicates that it is a value within a wider than usual range, adopted for classification purposes. When several different values are reported in the literature, the lowest is reported and used as the basis of classification, unless there are clear indications that a higher value is more reliable. Oral route values are used unless the dermal route values place the compound in a more hazardous class, or unless the dermal values are significantly lower than the oral values, although in the same class. Dermal LD50 values are indicated with the letter D.

Column 9: Remarks. This column is used to indicate cases in which the classification of a technical product has been adjusted (i.e., the oral LD50 value is not directly used as the basis of classification); Major irritant properties are also noted although they do not affect the classification. Sources of further information may also be given here: DS denotes a WHO/FAO Data Sheet on Pesticides, EHC an Environmental Health Criteria monograph, HSG a Health and Safety Guide, IARC IARC Monographs on the Evaluation of Carcinogenic Risks to Humans, ICSC an International Chemical Safety Card, JMPR an evaluation by the Joint FAO/WHO Meeting on Pesticide Residues and JECFA an evaluation by the the Joint FAO/WHO Expert Committee on Food Additives. These publications (with the exception of IARC Monographs) can be found on the IPCS web site (http://www.who.int/ipcs/).

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REFERENCES

Armstrong Lowe, D. and Stiles, A.R. (1973) Pesticides - nomenclature, specifications, analysis, use and residues in food, Bull. Wld. Hlth Org., 49, 169-204.

CICAD 6. Concise International Chemical Assessment Document 6 Biphenyl. Geneva, International Programme on Chemical Safety, 37 pp. 1999.

CICAD 13. Concise International Chemical Assessment Document 13 Triphenyltin compounds. Geneva, International Programme on Chemical Safety, 40 pp. 1999.

CICAD 40. Concise International Chemical Assessment Document 40 Formaldehyde. Geneva, In-ternational Programme on Chemical Safety, 75 pp. 2002.

CICAD 54. Concise International Chemical Assessment Document 40 Ethylene oxide. Geneva, In-ternational Programme on Chemical Safety, 57 pp. 2003.

CICAD 61. Concise International Chemical Assessment Document 61 Hydrogen cyanide and cyanides: Human health aspects. Geneva, International Programme on Chemical Safety, 67 pp. 2004.

DS. Pesticide Data Sheets. IPCS, Geneva, World Health Organization. See http://www.who.int/ipcs/publications/pds/en/index.html

Environmental Health Criteria 29 2,4-Dichlorophenoxyacetic Acid (2,4-D), Geneva, International Programme on Chemical Safety, 151 pp. 1984.

Environmental Health Criteria 34 Chlordane, Geneva, International Programme on Chemical Safety, 82 pp. 1984.

Environmental Health Criteria 38 Heptachlor, Geneva, International Programme on Chemical Safe-ty, 81 pp. 1984

Environmental Health Criteria 39 Paraquat and Diquat, Geneva, International Programme on Chemi-cal Safety, 173 pp. 1981.

Environmental Health Criteria 40 Endosulfan, Geneva, International Programme on Chemical Safe-ty, 109 pp. 1984.

Environmental Health Criteria 41 Quintozene, Geneva, International Programme on Chemical Safe-ty, 38 pp. 1984

Environmental Health Criteria 42 Tecnazene, Geneva, International Programme on Chemical Safety, 23 pp. 1984.

Environmental Health Criteria 43 Chlordecone, Geneva, International Programme on Chemical Safety, 57 pp. 1984.

Environmental Health Criteria 44 Mirex, Geneva, International Programme on Chemical Safety, 70 pp. 1984.

Environmental Health Criteria 45 Campechlor, Geneva, International Programme on Chemical Safe-ty, 66 pp. 1984.

Environmental Health Criteria 63 Organophosphorus Insecticides, Geneva, International Programme on Chemical Safety, 181 pp. 1986.

Environmental Health Criteria 64 Carbamate Pesticides, Geneva, International Programme on Chemical Safety, 136 pp. 1986.

Environmental Health Criteria 66 Kelevan, Geneva, International Programme on Chemical Safety, 32 pp. 1984.

Environmental Health Criteria 67 Tetradifon, Geneva, International Programme on Chemical Safety, 47 pp. 1986.

Environmental Health Criteria 71 Pentachlorophenol, Geneva, International Programme on Chemi-cal Safety, 236 pp. 1987.

Environmental Health Criteria 73 Phosphine and Selected Metal Phosphides, Geneva, International Programme on Chemical Safety, 100 pp. 1988.

Environmental Health Criteria 76 Thiocarbamate Pesticides, Geneva, International Programme on Chemical Safety, 49 pp. 1988.

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Environmental Health Criteria 78 Dithiocarbamate Pesticides, Ethylenethiourea, and propylenethio-urea, Geneva, International Programme on Chemical Safety, 140 pp. 1988.

Environmental Health Criteria 79 Dichlorvos, Geneva, International Programme on Chemical Safe-ty, 157 pp. 1989.

Environmental Health Criteria 82 Cypermethrin, Geneva, International Programme on Chemical Safety, 154 pp. 1989.

Environmental Health Criteria 83 DDT and its Derivatives - Environmental Aspects, Geneva, Inter-national Programme on Chemical Safety, 98 pp. 1989.

Environmental Health Criteria 84 2,4-Dichlorphenoxyacetic Acid – Environmental Aspects, Geneva, International Programme on Chemical Safety, 92 pp. 1989.

Environmental Health Criteria 87 Allethrins, Geneva, International Programme on Chemical Safety, 75 pp. 1989.

Environmental Health Criteria 90 Dimethoate, Geneva, International Programme on Chemical Safe-ty, 85 pp. 1989.

Environmental Health Criteria 92 Resmethrins; Geneva, International Programme on Chemical Safety, 79 pp. 1989.

Environmental Health Criteria 94 Permethrin; Geneva, International Programme on Chemical Safe-ty, 125 pp. 1990.

Environmental Health Criteria 95 Fenvalerate; Geneva, International Programme on Chemical Safe-ty, 121 pp. 1990.

Environmental Health Criteria 96 d-Phenothrin; Geneva, International Programme on Chemical Safety, 64 pp. 1990.

Environmental Health Criteria 97 Deltamethrin; Geneva, International Programme on Chemical Safety, 133 pp. 1990.

Environmental Health Criteria 98 Tetramethrin; Geneva, International Programme on Chemical Safety, 69 pp. 1990.

Environmental Health Criteria 99 Cyhalothrin; Geneva, International Programme on Chemical Safe-ty, 106 pp. 1990.

Environmental Health Criteria 121; Aldicarb; Geneva, International Programme on Chemical Safety, 130 pp. 1991.

Environmental Health Criteria 123 Alpha- and Beta Hexachlorocyclohexanes, Geneva, International Programme on Chemical Safety, 170 pp. 1992.

Environmental Health Criteria 124 Lindane; Geneva, International Programme on Chemical Safety, 208 pp. 1991.

Environmental Health Criteria 132 Trichlorfon; Geneva, International Programme on Chemical Safety, 162 pp. 1992.

Environmental Health Criteria 133 Fenitrothion; Geneva, International Programme on Chemical Safety, 184 pp. 1992.

Environmental Health Criteria 142 Alpha-cypermethrin; Geneva, International Programme on Chemical Safety, 112 pp. 1992.

Environmental Health Criteria 145 Methyl Parathion; Geneva, International Programme on Chemi-cal Safety, 244 pp. 1993.

Environmental Health Criteria 147 Propachlor, Geneva, International Programme on Chemical Safe-ty, 110 pp. 1993.

Environmental Health Criteria 148 Benomyl; Geneva, International Programme on Chemical Safety, 135 pp. 1993.

Environmental Health Criteria 149 Carbendazim; Geneva, International Programme on Chemical Safety, 132 pp. 1993.

Environmental Health Criteria 153 Carbaryl; Geneva, International Programme on Chemical Safety, 358 pp. 1993.

Environmental Health Criteria 158 Amitrole; Geneva, International Programme on Chemical Safety, 107 pp. 1994.

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Environmental Health Criteria 159 Glyphosate; Geneva, International Programme on Chemical Safety, 177 pp. 1994.

Environmental Health Criteria 166 Methyl bromide; Geneva, International Programme on Chemical Safety, 324 pp. 1995.

Environmental Health Criteria 175 Anticoagulant Rodenticides; Geneva, International Programme on Chemical Safety, 121 pp. 1995.

Environmental Health Criteria 176 1,2-dichloroethane (ethylene dichloride); (2nd edition), Geneva, International Programme on Chemical Safety, 148 pp. 1995.

Environmental Health Criteria 177 1,2-dibromoethane (ethylene dibromide); Geneva, International Programme on Chemical Safety, 146 pp. 1996.

Environmental Health Criteria 178 Methomyl; Geneva, International Programme on Chemical Safe-ty, 150 pp. 1996.

Environmental Health Criteria 182 Thallium, Geneva, International Programme on Chemical Safety, 274 pp. 1996.

Environmental Health Criteria 183 Chlorothalonil, Geneva, International Programme on Chemical Safety, 145 pp. 1996.

Environmental Health Criteria 184 Diflubenzuron, Geneva, International Programme on Chemical Safety, 164 pp. 1996.

Environmental Health Criteria 195 Hexachlorobenzene, Geneva, International Programme on Chem-ical Safety, 160 pp. 1997.

Environmental Health Criteria 198 Diazinon, Geneva, International Programme on Chemical Safety, 140 pp. 1998

Environmental Health Criteria 200 Copper, Geneva, International Programme on Chemical Safety, 360 pp. 1998.

Environmental Health Criteria 217 Bacillus thuringiensis, Geneva, International Programme on Chemical Safety, 105 pp. 1999.

Environmental Health Criteria 220 Dinitro-ortho-cresol, Geneva, International Programme on Chemical Safety, 87 pp. 2000.

Environmental Health Criteria 224 Arsenic and arsenic compounds (Second edition), Geneva, Inter-national Programme on Chemical Safety, 521 pp. 2001.

FAO (1985), Guidelines on good labelling practice for pesticides, Rome, Food and Agriculture Or-ganization of the United Nations, 36 pp.

FAO (1990), International Code of Conduct on the Distribution and Use of Pesticides: Rome, Food and Agriculture Organization of the United Nations, 34 pp.

HSGs. Health and Safety Guides, IPCS, Geneva, World Health Organization. See http://www.who.int/ipcs/publications/hsg/en/index.html

IARC 4. IARC Monographs on the Evaluation of Carcinogenic Risks to Humans Volume 4 Some Aromatic Amines, Hydrazyne and Related Substances, N-Nitroso Compounds and Miscellaneous Alkylation Agents. Lyon, International Agency for Research on Cancer, 286 pp. 1974

IARC 7. IARC Monographs on the Evaluation of Carcinogenic Risks to Humans Volume 12 Some Carbamates, Thiocarbamates and Carbazides. Lyon, International Agency for Research on Can-cer, 282 pp. 1976

IARC 41. IARC Monographs on the Evaluation of Carcinogenic Risks to Humans Volume 41 Some Halogenated Hydrocarbons and Pesticide Exposures. Lyon, International Agency for Research on Cancer, 434 pp. 1986.

IARC 53. Monographs on the Evaluation of Carcinogenic Risks to Humans Volume 53 Occupational Exposures in Insecticide Application and some Pesticides. Lyon, International Agency for Re-search on Cancer, 612 pp. 1991.

IARC 62. IARC Monographs on the Evaluation of Carcinogenic Risks to Humans Volume 6 Wood dust and formaldehyde. Lyon, International Agency for Research on Cancer, 405 pp. 1995.

15

IARC 63. IARC Monographs on the Evaluation of Carcinogenic Risks to Humans Volume 63 Dry cleaning , Some Chlorinated Solvents and Other Industrial Chemicals. Lyon, International Agen-cy for Research on Cancer, 558 pp. 1995.

IARC 71. IARC Monographs on the Evaluation of Carcinogenic Risks to Humans Volume 71 Re-evaluatio of some organic chemicals, hydrazine and hydrogen peroxide, Parts I-III1. Lyon, Inter-national Agency for Research on Cancer, 1586 pp. 1999.

IARC 73. IARC Monographs on the Evaluation of Carcinogenic Risks to Humans Volume 73 some chemicals taht cause tumours of the kidney or urinary bladder in rodents and some other sub-stances. Lyon, International Agency for Research on Cancer, 674 pp. 1999.

IARC 79. IARC Monographs on the Evaluation of Carcinogenic Risks to Humans Volume 79 some thyrotropic agents. Lyon, International Agency for Research on Cancer, 763 pp. 2001.

IARC 84. IARC Monographs on the Evaluation of Carcinogenic Risks to Humans Volume 84 some drinking water disinfectants and contaminants, including arsenic. Lyon, International Agency for Research on Cancer, 512 pp. 2004.

IARC Suppl 7. IARC Monographs on the Evaluation of Carcinogenic Risks to Humans Voverall evaluations of carcinogenicity: An updating of IARC Monographs volumes 1 to 42. Lyon, Inter-national Agency for Research on Cancer, 440 pp. 1987.

International Organization for Standardization (1981) Pesticides and other agrochemicals - common names, Geneva (ISO 1750). (Copies available only from national standards institutes).

ICSCs. International Chemical Safety Cards, IPCS, Geneva, World Health Organization. See http://www.ilo.org/public/english/protection/safework/cis/products/icsc/index.htm

JECFA (1996) Toxicological evaluation of certain veterinary drug residues in food prepared by the forty-seventh meeting of the Joint FAO/WHO Expert Committee on Food Additives (JECFA), WHO food additives series 38, Geneva, World Health Organization.

JECFA (1997) Toxicological evaluation of vertain veterinary drug residues in food prepared by the forty-eighth meeting of the Joint FAO/WHO Expert Committee on Food Additives (JECFA), WHO food additives series 39, Geneva, World Health Organization.

JECFA (2000a) Toxicological evaluation of vertain veterinary drug residues in food prepared by the fifty-second meeting of the Joint FAO/WHO Expert Committee on Food Additives (JECFA), WHO food additives series 43, Geneva, World Health Organization.

JECFA (2000b) Toxicological evaluation of vertain veterinary drug residues in food prepared by the fifty-fourth meeting of the Joint FAO/WHO Expert Committee on Food Additives (JECFA), WHO food additives series 45, Geneva, World Health Organization.

JECFA (2002) Toxicological evaluation of vertain veterinary drug residues in food prepared by the fifty-eighth meeting of the Joint FAO/WHO Expert Committee on Food Additives (JECFA), WHO food additives series 49, Geneva, World Health Organization.

JECFA (2003) Toxicological evaluation of vertain veterinary drug residues in food prepared by the sixtieth meeting of the Joint FAO/WHO Expert Committee on Food Additives (JECFA), WHO food additives series 51, Geneva, World Health Organization.

JMPR (1965a) Evaluation of the toxicity of pesticide residues in food. FAO Meeting Report, No. PL/1965/10/1; WHO/Food Add./27.65.

JMPR (1965b) Evaluation of the hazards to consumers resulting from the use of fumigants in the protection of food. FAO Meeting Report, No. PL/1965/10/2; WHO/Food Add./28.65.

JMPR (1967) Evaluation of some pesticide residues in food. FAO/PL:CP/15; WHO/Food Add./67.32.

JMPR (1969) 1968 Evaluation of some pesticide residues in food. FAO/PL:1968/M/9/1; WHO/Food Add./69.35.

JMPR (1971) 1970 Evaluations of some pesticide residues in food. AGP:1970/M/12/1; WHO/Food Add./71.42.

JMPR (1972) 1971 Evaluations of some pesticide residues in food. AGP:1971/M/9/1; WHO Pesti-cide Residues Series No. 1.

16

JMPR (1974) 1973 Evaluations of some pesticide residues in food. FAO/AGP/1973/M/9/1; WHO Pesticide Residues Series, No. 3.

JMPR (1978) Pesticide residues in food: 1977 evaluations. FAO Plant Production and Protection Paper 10 Sup.

JMPR (1979) Pesticide residues in food: 1978 evaluations. FAO Plant Production and Protection Paper 15 Sup.

JMPR (1980) Pesticide residues in food: 1979 evaluations. FAO Plant Production and Protection Paper 20 Sup.

JMPR (1982) Pesticide residues in food:1981 evaluations. FAO Plant Production and Protection Paper 42.

JMPR (1983) Pesticide residues in food: 1982 evaluations. FAO Plant Production and Protection Paper 49.

JMPR (1985a) Pesticide residues in food: 1983 evaluations. FAO Plant Production and Protection Paper 61.

JMPR (1985b) Pesticide residues in food – 1984. Report of the Joint Meeting on Pesticide Residues. FAO Plant Production and Protection Paper 62.

JMPR (1985c) Pesticide residues in food – 1984 evaluations. FAO Plant Production and Protection Paper 67.

JMPR (1986a) Pesticide residues in food – 1985. Report of the Joint Meeting of the FAO Panel of Experts on Pesticide Residues in Food and the Environment and a WHO Expert Group on Pesti-cide Residues. FAO Plant Production and Protection Paper 68.

JMPR (1986b) Pesticide residues in food – 1985 evaluations. Part II – Toxicology. FAO Plant Pro-duction and Protection Paper 72/2.

JMPR (1986c) Pesticide residues in food – 1986. Report of the Joint Meeting of the FAO Panel of Experts on Pesticide Residues in Food and the Environment and a WHO Expert Group on Pesti-cide Residues. FAO Plant Production and Protection Paper 77.

JMPR (1987a) Pesticide residues in food – 1986 evaluations. Part II – Toxicology. FAO Plant Pro-duction and Protection Paper 78/2.

JMPR (1987b) Pesticide residues in food – 1987. Report of the Joint Meeting of the FAO Panel of Experts on Pesticide Residues in Food and the Environment and a WHO Expert Group on Pesti-cide Residues. FAO Plant Production and Protection Paper 84.

JMPR (1988) Pesticide residues in food – 1987 evaluations. Part II – Toxicology. FAO Plant Produc-tion and Protection Paper 86/2.

JMPR (1989) Pesticide residues in food – 1988 evaluations. Part II – Toxicology. FAO Plant Produc-tion and Protection Paper 93/2.

JMPR (1990) Pesticide residues in food – 1989 evaluations. Part II – Toxicology. FAO Plant Produc-tion and Protection Paper 100/2.

JMPR (1991) Pesticide residues in food – 1990 evaluations. Part II – Toxicology. World Health Or-ganization (WHO/PCS/91.47).

JMPR (1992) Pesticide residues in food – 1991 evaluations. Part II – Toxicology. World Health Or-ganization (WHO/PCS/92.52).

JMPR (1993) Pesticide residues in food – 1992 evaluations. Part II – Toxicology. World Health Or-ganization (WHO/PCS/93.34).

JMPR (1994) Pesticide residues in food – 1993 evaluations. Part II – Toxicology. World Health Or-ganization (WHO/PCS/94.4).

JMPR (1995a) Pesticide residues in food – 1994. Report of the Joint Meeting of the FAO Panel of Experts on Pesticide Residues in Food and the Environment and a WHO Expert Group on Pesti-cide Residues. FAO Plant Production and Protection Paper, 127.

JMPR (1995b) Pesticide residues in food – 1994 evaluations. Part II – Toxicology. World Health Organization (WHO/PCS/95.2).

17

JMPR (1996a) Pesticide residues in food – 1995. Report of the Joint Meeting of the FAO Panel of Experts on Pesticide Residues in Food and the Environment and WHO Toxicological and Envi-ronmental Core Assessment Groups. FAO Plant Production and Protection Paper, 133.

JMPR (1996b) Pesticide residues in food – 1995 evaluations. Part II – Toxicological and Environ-mental. Geneva, World Health Organization (WHO/PCS/96.48).

JMPR (1997a) Pesticide residues in food – 1996. Report of the Joint Meeting of the FAO Panel of Experts on Pesticide Residues in Food and the Environment and the WHO Core Assessment Group. FAO Plant Production and Protection Paper, 140.

JMPR (1997b) Pesticide residues in food – 1996 evaluations. Part II – Toxicological and Environ-mental. Geneva, World Health Organization (WHO/PCS/97.1).

JMPR (1998a) Pesticide residues in food – 1997. Report of the Joint Meeting of the FAO Panel of Experts on Pesticide Residues in Food and the Environment and the WHO Core Assessment Group. FAO Plant Production and Protection Paper, 145.

JMPR (1998b) Pesticide residues in food – 1997 evaluations. Part II – Toxicological and Environ-mental. Geneva, World Health Organization (WHO/PCS/98.6).

JMPR (1999) Pesticide residues in food – 1998 evaluations. Part II – Toxicological. Geneva, World Health Organization (WHO/PCS/99.18).

JMPR (2000) Pesticide residues in food – 1999 evaluations. Part II – Toxicological and Environmen-tal. Geneva, World Health Organization (WHO/PCS/00.4).

JMPR (2001) Pesticide residues in food – 2000. Report of the Joint Meeting of the FAO Panel of Ex-perts on Pesticide Residues in Food and the Environment and the WHO Core Assessment Group. FAO Plant Production and Protection Paper 167.

JMPR (2002) Pesticide residues in food – 2001. Joint FAO/WHO Meeting on Pesticide Residues.Evaluations 2001. Part II Toxicological. IPCS International Programme on Chemical Safety & World Health Organization, Geneva

JMPR (2003a) Pesticide residues in food – 2002. Report 2002 of the Joint Meeting of the FAO Panel of Experts on Pesticide Residues in Food and the Environment and the WHO Core Assessment Group. FAO Plant Production and Protection Paper 172.

JMPR (2003b) Pesticide residues in food – 2002. Joint FAO/WHO Meeting on Pesticide Residues.Evaluations 2002. Part II Toxicological. IPCS International Programme on Chemical Safety & World Health Organization, Geneva

JMPR (2004a) Pesticide residues in food – 2003. Report of the Joint Meeting of the FAO Panel of Experts on Pesticide Residues in Food and the Environment and the WHO Core Assessment Group. FAO Plant Production and Protection Paper 176.

JMPR (2004b) Pesticide residues in food – 2003. Joint Meeting of the FAO Panel of Experts on Pes-ticide Residues in Food and the Environment and the WHO Core Assessment Group. Evaluations 2003. Part II Toxicological. IPCS, World Health Organization, Geneva (WHO/PCS/04.1).

JMPR (2005a) Pesticide residues in food – 2004. Report of the Joint Meeting of the FAO Panel of Experts on Pesticide Residues in Food and the Environment and the WHO Core Assessment Group. FAO Plant Production and Protection Paper 178.

JMPR (2005b) Pesticide residues in food – 2005. Report of the Joint Meeting of the FAO Panel of Experts on Pesticide Residues in Food and the Environment and the WHO Core Assessment Group. FAO Plant Production and Protection Paper 183.

JMPR (2006a) Pesticide residues in food – 2004. Joint Meeting of the FAO Panel of Experts on Pes-ticide Residues in Food and the Environment and the WHO Core Assessment Group. Evaluations 2004. Part II Toxicological. IPCS, World Health Organization, Geneva (WHO/PCS/06.1).

JMPR (2006b) Pesticide residues in food – 2005. Joint Meeting of the FAO Panel of Experts on Pes-ticide Residues in Food and the Environment and the WHO Core Assessment Group. Evaluations 2005. Part II Toxicological. IPCS, World Health Organization, Geneva.

JMPR (2006c) Pesticide residues in food – 2006. Report of the Joint Meeting of the FAO Panel of Experts on Pesticide Residues in Food and the Environment and the WHO Core Assessment Group on Pesticide Residues. FAO Plant Production and Protection Paper 187.

18

JMPR (2007) Pesticide residues in food – 2007. Report of the Joint Meeting of the FAO Panel of Ex-perts on Pesticide Residues in Food and the Environment and the WHO Core Assessment Group on Pesticide Residues. FAO Plant Production and Protection Paper 191.

JMPR (2008) Pesticide residues in food – 2006. Joint Meeting of the FAO Panel of Experts on Pes-ticide Residues in Food and the Environment and the WHO Core Assessment Group. Evaluations 2006. Part II Toxicological. IPCS, World Health Organization, Geneva.

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WHO/FAO Data Sheets on Pesticides; mimeographed series of documents, WHO/PCS Nos. 1-94, Geneva, World Health Organization. available at: http://www.inchem.org/pages/pds.html

Wiswesser, W.J., Pesticide Index, (1976), College Science Publishers, Entomological Society of America, 5th Edition, College Park, Maryland 20740, United States of America.

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19

Tabl

e 1.

Ext

rem

ely

haza

rdou

s (C

lass

Ia) t

echn

ical

gra

de a

ctiv

e in

gred

ient

s in

pes

ticid

es

Com

mon

nam

eC

AS

noU

N

noC

hem

ty

pePh

ys

stat

eM

ain

use

GH

SL

D50

m

g/kg

Rem

arks

Ald

icar

b [I

SO]

116-

06-3

2757

CS

I-S

10.

93D

S 53

; EH

C 1

21; H

SG 6

4; IA

RC

53;

ICSC

94;

JMPR

199

3, 1

996a

Bro

difa

coum

[ISO

]56

073-

10-0

3027

CO

SR

10.

3D

S 57

; EH

C 1

75; H

SG 9

3

Bro

mad

iolo

ne [I

SO]

2877

2-56

-730

27C

OS

R1

1.12

DS

88; E

HC

175

; HSG

94

Bro

met

halin

[ISO

]63

333-

35-7

2588

SR

12

Cal

cium

cya

nide

[C]

592-

01-8

1575

SFM

239

Adj

uste

d cl

assi

ficat

ion;

see

note

1; I

CSC

407

Cap

tafo

l [IS

O]

2425

-06-

1S

F5

5000

Adj

uste

d cl

assi

ficat

ion;

see

note

2; H

SG 4

9; IA

RC

53;

ICSC

119

; JM

PR 1

978,

198

6a; s

ee n

ote

3

Chl

oret

hoxy

fos [

ISO

]54

593-

83-8

3018

OP

LI

11.

8Ex

trem

ely

haza

rdou

s by

skin

con

tact

(LD

50 =

12.

5 m

g/kg

); IC

SC 1

681

Chl

orm

epho

s [IS

O]

2493

4-91

-630

18O

PL

I2

7IC

SC 1

682

Chl

orop

haci

none

[ISO

]36

91-3

5-8

2588

SR

13.

1D

S 62

; EH

C 1

75

Dife

naco

um [I

SO]

5607

3-07

-530

27C

OS

R1

1.8

EHC

175

; HSG

95

Dife

thia

lone

[ISO

]10

4653

-34-

125

88S

R1

0.56

EHC

175

Dip

haci

none

[ISO

]82

-66-

625

88S

R1

2.3

EHC

175

Dis

ulfo

ton

[ISO

]29

8-04

-430

18O

PL

I1

2.6

DS

68; J

MPR

199

2, 1

997a

; IC

SC 1

408

EPN

21

04-6

4-5

2783

OP

SI

214

See

note

4; I

CSC

753

Etho

prop

hos [

ISO

]13

194-

48-4

3018

OP

LI-

S2

D26

DS

70; J

MPR

200

0; IC

SC 1

660;

[Ora

l LD

50 =

33

mg/

kg]

Floc

oum

afen

9003

5-08

-830

27S

R1

0.25

EHC

175

; IC

SC 1

267

Hex

achl

orob

enze

ne [I

SO]

118-

74-1

2729

OC

SFS

T5

D10

000

Adj

uste

d cl

assi

ficat

ion

(not

es 3

and

5);

IAR

C 7

9; IC

SC 8

95; E

HC

195

Mer

curic

chl

orid

e [I

SO]

7487

-94-

716

24H

GS

F-S

11

See

note

3; I

CSC

979

Mev

inph

os [I

SO]

2671

8-65

-030

18O

PL

I1

D4

DS

14; I

CSC

924

; JM

PR 1

998b

; [O

ral L

D50

= 3

.7 m

g/kg

]

Para

thio

n [I

SO]

56-3

8-2

3018

OP

LI

213

See

note

3; D

S 6;

HSG

74;

IAR

C 3

0, S

uppl

. 7; I

CSC

6; J

MPR

199

6b

Para

thio

n-m

ethy

l [IS

O]

298-

00-0

3018

OP

LI

214

See

note

3; D

S 7;

EH

C 1

45; H

SG 7

5; IC

SC 6

26; J

MPR

198

5c, 1

996b

20

Com

mon

nam

eC

AS

noU

N

noC

hem

ty

pePh

ys

stat

eM

ain

use

GH

SL

D50

m

g/kg

Rem

arks

Phen

ylm

ercu

ry a

ceta

te [I

SO]

62-3

8-4

1674

HG

SFS

T2

24A

djus

ted

clas

sific

atio

n; se

e no

tes 3

and

6; I

CSC

540

Phor

ate

[ISO

]29

8-02

-230

18O

PL

I1

2D

S 75

; JM

PR 1

997b

, 200

5; IC

SC 1

060

Phos

pham

idon

1317

1-21

-630

18O

PL

I2

7Se

e no

te 3

; DS

74; I

CSC

189

; JM

PR 1

987b

C

AS

Nos

for E

and

Z is

omer

s 297

-99-

4 an

d 23

783-

98-4

Sodi

um fl

uoro

acet

ate

[C]

62-7

4-8

2629

SR

10.

2D

S 16

; IC

SC 4

84

Sulfo

tep

[ISO

]36

89-2

4-5

1704

OP

LI

15

ICSC

985

Tebu

pirim

fos [

ISO

*]96

182-

53-5

3018

OP

LI

11.

3Ex

trem

ely

haza

rdou

s by

skin

con

tact

(LD

50 9

.4 m

g/kg

in ra

ts)

Terb

ufos

[ISO

]13

071-

79-9

3018

OP

LI-

S1

c2JM

PR 1

991,

200

4

EHC

= E

nviro

nmen

tal

Hea

lth C

riter

ia M

onog

raph

; D

S =

Pest

icid

e D

ata

Shee

t; H

SG =

Hea

lth a

nd S

afet

y G

uide

; IA

RC

= I

AR

C M

onog

raph

s on

the

Eva

luat

ion

of

Car

cino

geni

c R

isks

to H

uman

s; IC

SC =

Inte

rnat

iona

l Che

mic

al S

afet

y C

ard;

JMPR

= E

valu

atio

n by

the

Join

t FA

O/W

HO

Mee

ting

on P

estic

ide

Res

idue

s.

Not

es to

Cla

ss Ia

1.

Cal

cium

cya

nide

is in

Cla

ss Ia

as i

t rea

cts w

ith m

oist

ure

to p

rodu

ce h

ydro

gen

cyan

ide

gas.

The

gas i

s not

cla

ssifi

ed u

nder

the

WH

O sy

stem

(see

Tab

le 8

).2.

C

apta

fol i

s car

cino

geni

c in

bot

h ra

ts a

nd m

ice.

3.

The

inte

rnat

iona

l tra

de o

f cap

tafo

l, he

xach

loro

benz

ene,

mer

cury

com

poun

ds, p

arat

hion

, par

athi

on-m

ethy

l, an

d ph

osph

amid

on is

regu

late

d by

the

Rot

terd

am c

onve

ntio

n on

Prio

r Inf

orm

ed C

onse

nt (s

ee h

ttp://

ww

w.pi

c.in

t/), w

hich

ent

ered

into

forc

e on

24

Febr

uary

200

4. S

ee T

able

7, p

. 51

4.

EPN

has

bee

n re

porte

d as

cau

sing

del

ayed

neu

roto

xici

ty in

hen

s.5.

H

exac

hlor

oben

zene

has

cau

sed

a se

rious

out

brea

k of

por

phyr

ia in

hum

ans.

The

use

and

prod

uctio

n of

hex

achl

orob

enze

ne is

sev

erel

y re

stric

ted

by th

e St

ockh

olm

co

nven

tion

on p

ersi

sten

t org

anic

pol

luta

nts,

whi

ch e

nter

ed in

to fo

rce

on 1

7 M

ay, 2

004.

See

http

://w

ww.

pops

.int/

6.

Phen

ylm

ercu

ry a

ceta

te is

hig

hly

toxi

c to

mam

mal

s and

ver

y sm

all d

oses

hav

e pr

oduc

ed re

nal l

esio

ns: t

erat

ogen

ic in

the

rat.

THE

FIN

AL

CLA

SSIF

ICAT

ION

OF

AN

Y P

RO

DU

CT

DEP

END

S O

N IT

S FO

RM

ULA

TIO

NSe

e Pa

ges 7

& 8

, and

the A

nnex

21

Tabl

e 2.

Hig

hly

haza

rdou

s (C

lass

Ib) t

echn

ical

gra

de a

ctiv

e in

gred

ient

s in

pes

ticid

es

Com

mon

nam

eC

AS

noU

N

noC

hem

ty

pePh

ys

stat

eM

ain

use

GH

SL

D50

m

g/kg

Rem

arks

Acr

olei

n [C

]10

7-02

-810

92L

H2

29EH

C 1

27; H

SG 6

7; IA

RC

63;

ICSC

90

Ally

l alc

ohol

[C]

107-

18-6

1098

LH

364

Hig

hly

irrita

nt to

skin

and

eye

s; IC

SC 9

5; A

djus

ted

clas

sific

atio

n

(see

not

e 3)

Azi

npho

s-et

hyl [

ISO

]26

42-7

1-9

2783

OP

SI

212

DS

72; J

MPR

197

4A

zinp

hos-

met

hyl [

ISO

]86

-50-

027

83O

PS

I2

16D

S 59

; IC

SC 8

26; J

MPR

199

2, 2

009b

Bla

stic

idin

-S20

79-0

0-7

2588

SF

216

But

ocar

boxi

m [I

SO]

3468

1-10

-229

92C

LI

315

8JM

PR 1

986a

; Adj

uste

d cl

assi

ficat

ion

(see

not

e 3)

But

oxyc

arbo

xim

[ISO

]34

681-

23-7

2992

CL

I3

D28

8Ad

just

ed c

lass

ifica

tion

(see

not

e 3)

Cad

usaf

os [I

SO]

9546

5-99

-930

18O

PL

N,I

237

JMPR

199

2C

alci

um a

rsen

ate

[C]

7778

-44-

115

73A

SS

I2

20EH

C 1

8, 2

24; I

AR

C 8

4; IC

SC 7

65; J

MPR

196

9C

arbo

fura

n [I

SO]

1563

-66-

227

57C

SI

28

DS

56; I

CSC

122

; JM

PR 1

997b

, 200

3b, 2

009a

; See

not

e 2.

Chl

orfe

nvin

phos

[ISO

]47

0-90

-630

18O

PL

I2

31IC

SC 1

305;

JMPR

199

5b3-

Chl

oro-

1,2-

prop

aned

iol

[C]

96-2

4-2

2689

LR

311

2Ad

just

ed c

lass

ifica

tion

(see

not

es 1

and

3)

Cou

map

hos [

ISO

]56

-72-

427

83O

PS

AC

,MT

27.

1IC

SC 4

22; J

MPR

199

1C

oum

atet

raly

l [IS

O]

5836

-29-

330

27C

OS

R2

16C

yflut

hrin

[ISO

]68

359-

37-5

PYS

I2

c15

JMPR

200

8; S

ee n

ote

9, p

. 8Be

ta-c

yflut

hrin

[ISO

]68

359-

37-5

PYS

I2

c11

JMPR

200

8; S

ee n

ote

9, p

. 8Ze

ta-c

yper

met

hrin

[ISO

]52

315-

07-8

3352

PYL

I3

c86

See

note

9, p

. 8; H

SG 2

2; IC

SC 2

46; J

MPR

200

8; A

djus

ted

clas

sific

atio

n (s

ee n

ote

3)D

emet

on-S

-met

hyl [

ISO

]91

9-86

-830

18O

PL

I2

40D

S 61

, EH

C 1

97; I

CSC

705

; JM

PR 1

990

Dic

hlor

vos [

ISO

]62

-73-

730

18O

PL

I3

56Vo

latil

e, D

S 2;

EH

C 7

9; H

SG 1

8; IA

RC

20,

53;

ICSC

690

; JM

PR

1994

; Adj

uste

d cl

assi

ficat

ion

(see

not

e 3)

Dic

roto

phos

[ISO

]14

1-66

-230

18O

PL

I2

22IC

SC 8

72D

inot

erb

[ISO

]14

20-0

7-1

2779

NP

SH

225

22

Com

mon

nam

eC

AS

noU

N

noC

hem

ty

pePh

ys

stat

eM

ain

use

GH

SL

D50

m

g/kg

Rem

arks

DN

OC

[ISO

]53

4-52

-127

79N

PS

I-S,

H2

25JM

PR 1

965a

; EH

C 2

20; I

CSC

462

. See

not

e 2.

Edife

npho

s [IS

O]

1710

9-49

-830

18O

PL

F3

150

JMPR

198

2. A

djus

ted

clas

sific

atio

n (s

ee n

ote

3)Et

hiof

enca

rb [I

SO]

2997

3-13

-529

92C

LI

320

0JM

PR 1

983.

Adj

uste

d cl

assi

ficat

ion

(see

not

e 3)

Fam

phur

52-8

5-7

2783

OP

SI

248

Fena

mip

hos [

ISO

]22

224-

92-6

2783

OP

SN

215

DS

92; I

CSC

483

; JM

PR 1

998b

, 200

3bFl

ucyt

hrin

ate

[ISO

]70

124-

77-5

3352

PYL

I3

c67

JMPR

198

6b; s

ee n

ote

9, p

.8; A

djus

ted

clas

sific

atio

n (s

ee n

ote

3)Fl

uoro

acet

amid

e [C

]64

0-19

-725

88S

R2

13IC

SC 1

434.

See

not

e 2

Form

etan

ate

[ISO

]22

259-

30-9

2757

CS

AC

221

Fura

thio

carb

6590

7-30

-429

92C

LI-

S2

42H

epte

noph

os [I

SO]

2356

0-59

-030

18O

PL

I3

96Ad

just

ed c

lass

ifica

tion

(see

not

e 3)

Isox

athi

on [I

SO]

1885

4-04

-830

18O

PL

I3

112

Adju

sted

cla

ssifi

catio

n (s

ee n

ote

3)Le

ad a

rsen

ate

[C]

7784

-40-

916

17A

SS

L2

c10

EHC

18,

224

; IA

RC

84;

ICSC

911

; JM

PR 1

969

Mec

arba

m [I

SO]

2595

-54-

230

18O

PO

ilI

236

JMPR

198

7aM

ercu

ric o

xide

[ISO

]21

908-

53-2

1641

HG

SO

218

ICSC

981

; CIC

AD

50.

See

not

e 2

Met

ham

idop

hos [

ISO

]10

265-

92-6

2783

OP

SI

230

HSG

79;

ICSC

176

; JM

PR 1

991,

200

3b; S

ee n

ote

2M

ethi

dath

ion

[ISO

]95

0-37

-830

18O

PL

I2

25JM

PR 1

998b

; IC

SC 1

659

Met

hioc

arb

[ISO

]20

32-6

5-7

2757

CS

I2

20JM

PR 1

999

Met

hom

yl [I

SO]

1675

2-77

-527

57C

SI

217

DS

55, E

HC

178

; HSG

97;

ICSC

177

, JM

PR 1

989,

200

2M

onoc

roto

phos

[ISO

]69

23-2

2-4

2783

OP

SI

214

See

note

2; H

SG 8

0; IC

SC 1

81; J

MPR

199

6bN

icot

ine

[ISO

]54

-11-

516

54L

1D

50IC

SC 5

19O

met

hoat

e [I

SO]

1113

-02-

630

18O

PL

I2

50JM

PR 1

997a

Oxa

myl

[ISO

]23

135-

22-0

2757

CS

I2

6D

S 54

; JM

PR 1

986b

, 200

3bO

xyde

met

on-m

ethy

l [IS

O]

301-

12-2

3018

OP

LI

365

JMPR

199

0, 2

003b

; Adj

uste

d cl

assi

ficat

ion

(see

not

e 3)

Paris

gre

en [C

]12

002-

03-8

1585

AS

SL

222

Cop

per-a

rsen

ic c

ompl

exPe

ntac

hlor

ophe

nol [

ISO

]87

-86-

531

55S

I,F,H

2D

80Se

e no

te 2

; Irr

itant

to sk

in; E

HC

71;

HSG

19;

IAR

C 2

0, 5

3; IC

SC 6

9

23

Com

mon

nam

eC

AS

noU

N

noC

hem

ty

pePh

ys

stat

eM

ain

use

GH

SL

D50

m

g/kg

Rem

arks

Prop

etam

phos

[ISO

]31

218-

83-4

3018

OP

LI

310

6Ad

just

ed c

lass

ifica

tion

(see

not

e 3)

Sodi

um a

rsen

ite [C

]77

84-4

6-5

1557

AS

SR

210

EHC

224

; IA

RC

84;

ICSC

160

3So

dium

cya

nide

[C]

143-

33-9

1689

SR

26

ICSC

111

8; C

ICA

D 6

1St

rych

nine

[C]

57-2

4-9

1692

SR

216

ICSC

197

Teflu

thrin

7953

8-32

-233

49PY

SI-

S2

c22

See

note

9, p

. 8Th

alliu

m su

lfate

[C]

7446

-18-

617

07S

R2

11D

S 10

, EH

C 1

82; I

CSC

336

Thio

fano

x [I

SO]

3919

6-18

-427

57C

SI-

S2

8Th

iom

eton

[ISO

]64

0-15

-330

18O

PO

ilI

312

0D

S 67

; IC

SC 5

80; J

MPR

198

0; A

djus

ted

clas

sific

atio

n (s

ee n

ote

3)Tr

iazo

phos

[ISO

]24

017-

47-8

3018

OP

LI

382

JMPR

199

4, 2

003b

; Adj

uste

d cl

assi

ficat

ion

(see

not

e 3)

Vam

idot

hion

[ISO

]22

75-2

3-2

3018

OP

LI

310

3JM

PR 1

989;

ICSC

758

; Adj

uste

d cl

assi

ficat

ion

(see

not

e 3)

War

farin

[ISO

]81

-81-

230

27C

OS

R2

10D

S 35

, EH

C 1

75; H

SG 9

6; IC

SC 8

21Zi

nc p

hosp

hide

[C]

1314

-84-

717

14S

R2

45D

S 24

, EH

C 7

3; IC

SC 6

02

EHC

= E

nviro

nmen

tal H

ealth

Crit

eria

Mon

ogra

ph; D

S= P

estic

ide D

ata S

heet

; HSG

= H

ealth

and

Safe

ty G

uide

; IA

RC

= IA

RC

Mon

ogra

phs o

n th

e Eva

luat

ion

of C

arci

noge

nic

Ris

ks to

Hum

ans;

ICSC

= In

tern

atio

nal C

hem

ical

Saf

ety

Car

d; JM

PR =

Eva

luat

ion

by th

e Jo

int F

AO

/WH

O M

eetin

g on

Pes

ticid

e R

esid

ues.

Not

es to

Cla

ss Ib

1.

3-C

hlor

o-1,

2-pr

opan

edio

l in

nonl

etha

l dos

age

is a

ster

ilant

for m

ale

rats

. Thi

s com

poun

d is

als

o kn

own

as a

lpha

chl

orhy

drin

.2.

Th

e in

tern

atio

nal

trade

of

carb

ofur

an, D

NO

C, fl

uoro

acet

amid

e, m

ercu

ry c

ompo

unds

, met

ham

idop

hos,

mon

ocro

toph

os a

nd p

enta

chlo

roph

enol

is

regu

late

d by

the

R

otte

rdam

con

vent

ion

on P

rior I

nfor

med

Con

sent

(see

http

://w

ww.

pic.

int/)

, whi

ch e

nter

ed in

to fo

rce

on 2

4 Fe

brua

ry 2

004.

See

Tab

le 7

, p. 5

1.3.

A

s a

prec

autio

nary

mea

sure

, the

cla

ssifi

catio

n of

cer

tain

liqu

id p

estic

ides

has

bee

n ad

just

ed to

avo

id th

ose

pest

icid

es b

eing

ass

igne

d to

a le

ss h

azar

dous

Cla

ss in

the

proc

ess o

f alig

ning

the W

HO

Cla

ssifi

catio

n w

ith th

e G

HS.

Det

ails

of h

ow th

e WH

O C

lass

ifica

tion

has b

een

alig

ned

with

the

GH

S A

cute

Tox

icity

Haz

ard

Cat

egor

ies a

re

desc

ribed

in th

e in

trodu

ctor

y no

tes f

or P

art I

I.

THE

FIN

AL

CLA

SSIF

ICAT

ION

OF

AN

Y P

RO

DU

CT

DEP

END

S O

N IT

S FO

RM

ULA

TIO

NSe

e Pa

ges 7

& 8

, and

the A

nnex

24

Tabl

e 3.

Mod

erat

ely

haza

rdou

s (C

lass

II) t

echn

ical

gra

de a

ctiv

e in

gred

ient

s in

pes

ticid

es

Com

mon

nam

eC

AS

noU

N

noC

hem

ty

pePh

ys

stat

eM

ain

use

GH

SL

D50

m

g/kg

Rem

arks

Ace

phat

e [I

SO]

3056

0-19

-1O

PS

I4

945

JMPR

199

1, 2

003b

, 200

6b; I

CSC

748

Aci

fluor

fen

[ISO

]50

594-

66-6

SH

413

70St

rong

irrit

ant t

o ey

esA

lach

lor [

ISO

]15

972-

60-8

2588

SH

493

0Se

e no

te 1

; DS

86; I

AR

C 1

9, 3

6, 6

3; IC

SC 3

71A

lany

carb

[ISO

]83

130-

01-2

CS

I4

330

Alle

thrin

[ISO

]58

4-79

-2PY

Oil

I4

c685

See

note

9, p

age

8; E

HC

87;

HSG

24;

ICSC

212

; JM

PR 1

965a

Am

etry

n [I

SO]

834-

12-8

TS

H4

110

Am

itraz

[ISO

]33

089-

61-1

SA

C4

800

ICSC

98;

JMPR

199

9A

nilo

fos [

ISO

]64

249-

01-0

OP

SH

447

2A

zaco

nazo

le60

207-

31-0

SF

430

8A

zam

ethi

phos

[ISO

]35

575-

96-3

OP

SI

410

10A

zocy

clot

in [I

SO]

4108

3-11

-827

86O

TS

AC

380

JMPR

199

0, 1

995b

, 200

6bB

endi

ocar

b [I

SO]

2278

1-23

-327

57C

SI

355

DS

52B

enfu

raca

rb [I

SO]

8256

0-54

-129

92C

LI

320

5B

ensu

lide

[ISO

]74

1-58

-229

02L

H3

270

ICSC

383

Ben

sulta

p [I

SO]

1760

6-31

-4S

I4

1100

Ben

tazo

ne [I

SO]

2505

7-89

-0S

H4

1100

HSG

48;

ICSC

828

; JM

PR 1

999,

200

5B

ifent

hrin

8265

7-04

-333

49PY

SI

3c5

5JM

PR 1

993

Bila

nafo

s [IS

O]

7104

8-99

-2S

H3

268

Bio

alle

thrin

[C]

584-

79-2

PYL

I4

c700

See

note

2; n

ote

9, p

. 8; I

CSC

227

Bro

mox

ynil

[ISO

]16

89-8

4-5

2588

SH

319

0B

rom

ucon

azol

e11

6255

-48-

2S

F4

365

ICSC

126

4B

rono

pol

52-5

1-7

SB

325

4IC

SC 4

15B

utam

ifos [

ISO

]36

335-

67-8

OP

LH

463

0B

utra

lin [I

SO]

3362

9-47

-9S

H4

1049

25

Com

mon

nam

eC

AS

noU

N

noC

hem

ty

pePh

ys

stat

eM

ain

use

GH

SL

D50

m

g/kg

Rem

arks

But

roxy

dim

[ISO

]13

8164

-12-

2S

H4

1635

But

ylam

ine

[ISO

]13

952-

84-6

1992

LF

438

0Ir

ritan

t to

skin

; IC

SC 4

01; J

MPR

198

2, 1

985b

Car

bary

l [IS

O]

63-2

5-2

2757

CS

I3

c300

DS

3; E

HC

153

; HSG

78;

IAR

C 1

2, S

uppl

.7; I

CSC

121

; JM

PR

1997

b, 2

002

Car

bosu

lfan

[ISO

]55

285-

14-8

2992

CL

I3

250

JMPR

198

7a, 2

004

Car

tap

[ISO

]15

263-

53-3

SI

432

5EH

C 7

6; JM

PR 1

996a

Chl

oral

ose

[C]

1587

9-93

-3S

R4

400

Chl

orda

ne [I

SO]

57-7

4-9

2996

OC

LI

446

0Se

e no

tes 3

and

4; D

S 36

; EH

C 3

4; H

SG 1

3; IA

RC

79;

ICSC

740

; JM

PR 1

995a

Chl

orfe

napy

r [IS

O]

1224

53-7

3-0

SI,M

T4

441

Chl

orm

equa

t (ch

lorid

e) [I

SO]

999-

81-5

SPG

R4

670

ICSC

781

; JM

PR 2

000

Chl

oroa

cetic

aci

d [C

]79

-11-

817

51S

H4

650

Irrit

ant t

o sk

in a

nd e

yes;

dat

a re

fer t

o so

dium

salt;

ICSC

235

Chl

orph

oniu

m c

hlor

ide

[ISO

]11

5-78

-625

88S

PGR

317

8Ir

ritan

t to

skin

and

eye

sC

hlor

pyrif

os [I

SO]

2921

-88-

227

83O

PS

I3

135

DS

18; I

CSC

851

; JM

PR 2

000

Clo

maz

one

[ISO

]81

777-

89-1

LH

413

69C

oppe

r hyd

roxi

de [C

]20

427-

59-2

CU

SF

410

00C

oppe

r oxy

chlo

ride

[C]

1332

-40-

7C

US

F4

1440

Cop

per s

ulfa

te [C

]77

58-9

8-7

CU

SF

330

0IC

SC 7

514-

CPA

[ISO

]12

2-88

-3PA

AS

PGR

485

0C

upro

us o

xide

[C]

1317

-39-

1C

US

F4

470

ICSC

421

, EH

C 2

00C

yana

zine

[ISO

]21

725-

46-2

TS

H3

288

ICSC

391

Cya

noph

os [I

SO]

2636

-26-

2O

PL

I4

610

Cyh

alot

hrin

[ISO

]68

085-

85-8

3352

PYO

ilIx

3c1

44Se

e no

te 9

, p. 8

; EH

C 9

9; H

SG 3

8; IC

SC 8

58; J

MPR

198

5c;

JEC

FA 2

000b

Cyh

exat

in [I

SO]

1312

1-70

-5O

TS

AC

326

5EH

C 1

5; JM

PR 1

995b

, 200

6bC

ymox

anil

[ISO

]57

966-

95-7

SF

411

96

26

Com

mon

nam

eC

AS

noU

N

noC

hem

ty

pePh

ys

stat

eM

ain

use

GH

SL

D50

m

g/kg

Rem

arks

Cyp

erm

ethr

in [I

SO]

5231

5-07

-833

52PY

LI

3c2

50Se

e no

te 9

, p. 8

; DS

58; E

HC

82;

HSG

22;

ICSC

246

; JEC

FA 1

996

Alp

ha-c

yper

met

hrin

[ISO

]67

375-

30-8

3349

PYS

I3

c79

See

note

9, p

8; E

HC

142

; JEC

FA 1

996;

JM

PR 2

008

Cyp

heno

thrin

[(1R

)-is

omer

s]

[ISO

]39

515-

40-7

3352

PYL

I4

318

Cyp

roco

nazo

le94

361-

06-5

SF

410

202,

4-D

[ISO

]94

-75-

733

45PA

AS

H4

375

DS

37; E

HC

29,

84;

HSG

5; I

AR

C 4

1, S

uppl

. 7; I

CSC

33;

JMPR

19

98b

Daz

omet

[ISO

]53

3-74

-4S

F-S

464

0Ir

ritan

t to

skin

and

eye

s; IC

SC 7

862,

4-D

B94

-82-

6S

H4

700

DD

T [I

SO]

50-2

9-3

2761

OC

SI

311

3Se

e no

tes 3

and

4; D

S 21

; EH

C 9

, 83;

IAR

C 5

3; IC

SC 3

4; JM

PR

1985

c, 2

001

Del

tam

ethr

in [I

SO]

5291

8-63

-533

49PY

SI

3c1

35Se

e no

te 9

, p. 8

; DS

50; E

HC

97;

HSG

30;

IAR

C 5

3; IC

SC 2

47;

JMPR

200

1D

iazi

non

[ISO

]33

3-41

-530

18O

PL

I4

300

DS

45, E

HC

198

; IC

SC 1

37; J

MPR

199

4, 2

002,

200

8D

icam

ba [I

SO]

1918

-00-

9S

H4

1707

ICSC

139

Dic

hlor

oben

zene

[C]

106-

46-7

SFM

450

0-50

00M

ixtu

re o

f iso

mer

s: o

rtho

(3) 9

5-50

-1, m

eta

(3) 5

41-7

3-1,

par

a (2

B)

106-

46-7

; IC

SC 3

7D

ichl

orop

hen

[ISO

]97

-23-

4O

CS

F4

1250

Dic

hlor

prop

[ISO

]75

47-6

6-2

SH

480

0IC

SC 3

8D

iclo

fop

[ISO

]40

483-

25-2

SH

456

5D

icof

ol [I

SO]

115-

32-2

OC

SA

C4

c690

DS

81; I

AR

C 3

0; IC

SC 7

52; J

MPR

199

3D

ifeno

cona

zole

[ISO

]11

9446

-68-

3S

F4

1453

JMPR

200

9bD

ifenz

oqua

t [IS

O]

4322

2-48

-625

88S

H4

470

Dim

epip

erat

e [I

SO]

6143

2-55

-1TC

SH

494

6D

imet

hach

lor [

ISO

]50

563-

36-5

SH

416

00D

imet

hipi

n [I

SO]

5529

0-64

-7S

H4

1180

JMPR

200

0, 2

005

27

Com

mon

nam

eC

AS

noU

N

noC

hem

ty

pePh

ys

stat

eM

ain

use

GH

SL

D50

m

g/kg

Rem

arks

Dim

ethe

nam

id [I

SO]

8767

4-68

-8L

H4

371

LD50

of P

isom

er is

429

mg/

kg b

w; J

MPR

200

6bD

imet

hyla

rsin

ic a

cid

[C]

75-6

0-5

1572

AS

SH

413

50D

imet

hoat

e [I

SO]

60-5

1-5

2783

OP

SI

3c1

50D

S 42

; EH

C 9

0; H

SG 2

0; IC

SC 7

41; J

MPR

199

7b, 2

004

Din

icon

azol

e [I

SO]

8365

7-24

-3S

F4

639

Din

obut

on [I

SO]

973-

21-7

2779

NP

SA

C,F

314

0D

inoc

ap [I

SO]

3930

0-45

-3N

PS

AC

,F4

980

ICSC

881

; JM

PR 1

999

Dip

hena

mid

[ISO

]95

7-51

-7S

H4

970

ICSC

763

Diq

uat [

ISO

]27

64-7

2-9

2781

BP

SH

323

1Ir

ritan

t to

skin

and

eye

s and

dam

ages

nai

ls; D

S 40

; EH

C 3

9; H

SG

52; J

MPR

199

4; IC

SC 1

363

Dith

iano

n [I

SO]

3347

-22-

6S

F4

640

JMPR

199

3D

odin

e [I

SO]

2439

-10-

3S

F4

1000

JMPR

200

1En

dosu

lfan

[ISO

]11

5-29

-727

61O

CS

I3

80D

S 15

; EH

C 4

0; H

SG 1

7; IC

SC 7

42; J

MPR

199

9En

doth

al-s

odiu

m [(

ISO

)]12

5-67

-925

88S

H3

51EP

TC [I

SO]

759-

94-4

TCL

H4

1652

ICSC

469

Esfe

nval

erat

e [I

SO]

6623

0-04

-433

49PY

SI

387

JMPR

200

3b; I

CSC

151

6Et

hion

[ISO

]56

3-12

-230

18O

PL

I3

208

ICSC

888

; JM

PR 1

991

Fena

zaqu

in [I

SO]

1209

28-0

9-8

2588

SA

C3

134

Feni

troth

ion

[ISO

]12

2-14

-5O

PL

I4

503

DS

30; E

HC

133

; HSG

65;

ICSC

622

; JM

PR 2

001

Feno

buca

rb37

66-8

1-2

CS

I4

620

Feno

thio

carb

[ISO

]62

850-

32-2

CS

L4

1150

Fenp

ropi

din

[ISO

]67

306-

00-7

LF

414

40Fe

npro

path

rin [I

SO]

6425

7-84

-733

49PY

SI

3c6

6Se

e no

te 9

, p. 8

; JM

PR 1

994

Fenp

yrox

imat

e [I

SO]

1340

98-6

1-6

SAC

324

5H

ighl

y to

xic

by in

hala

tion

(LC

50 =

0.2

1-0.

36 m

g/l);

JM

PR 2

007

Fent

hion

[ISO

]55

-38-

930

18O

PL

I,L3

D58

6D

S 23

; IC

SC 6

55; J

MPR

199

8bFe

ntin

ace

tate

[(IS

O)]

900-

95-8

2786

OT

SF

312

5D

S 22

; EH

C 1

5; JM

PR 1

992;

CIC

AD

13

28

Com

mon

nam

eC

AS

noU

N

noC

hem

ty

pePh

ys

stat

eM

ain

use

GH

SL

D50

m

g/kg

Rem

arks

Fent

in h

ydro

xide

[(IS

O)]

76-8

7-9

2786

OT

SF

310

8D

S 22

; EH

C 1

5; IC

SC 1

283;

JMPR

199

2; C

ICAD

13

Fenv

aler

ate

[ISO

]51

630-

58-1

3352

PYL

I4

c450

See

note

9, p

. 8; D

S 90

; EH

C 9

5, H

SG 3

4; IA

RC

53;

ICSC

273

; JM

PR 1

986c

Ferim

zone

[ISO

]89

269-

64-7

SF

472

5Fi

pron

il12

0068

-37-

325

88S

I3

92JM

PR 1

998b

, 200

1; IC

SC 1

503

Fluc

hlor

alin

[ISO

]33

245-

39-5

SH

415

50Fl

ufen

acet

[ISO

]14

2459

-58-

3S

H4

600

May

cau

se sk

in se

nsiti

zatio

nFl

uoro

glyc

ofen

7750

1-60

-1S

H4

1550

Flur

prim

idol

[ISO

]56

425-

91-3

SPG

R4

709

Flus

ilazo

le85

509-

19-9

SF

467

2JM

PR 1

996b

, 200

9bFl

utria

fol [

ISO

]76

674-

21-0

SF,

FST

411

40Fl

uxof

enim

[ISO

]88

485-

37-4

oil

H4

670

Fom

esaf

en [I

SO]

7217

8-02

-0O

CS

H4

1250

Fube

ridaz

ole

[ISO

]38

78-1

9-1

SF

433

6Fu

rala

xyl [

ISO

]57

646-

30-7

SF

494

0G

amm

a-H

CH

[ISO

], Li

ndan

e58

-89-

927

61O

CS

I3

88IC

SC 5

3; JM

PR 2

003b

; See

not

e 3

Glu

fosi

nate

[ISO

]53

369-

07-6

SH

416

25JM

PR 2

000

Gua

zatin

e10

8173

-90-

6S

FST

323

0LD

50 v

alue

refe

rs to

tria

ceta

te; J

MPR

199

8bH

alox

yfop

6980

6-34

-4S

H4

300

JMPR

199

6b, 2

008

(incl

udes

Hal

oxyf

op-R

and

est

ers)

HC

H [I

SO]

608-

73-1

2761

OC

SI

310

0Se

e no

tes 3

, 4 a

nd 5

; EH

C 1

23; I

AR

C 5

, 20,

42;

ICSC

487

; JM

PR

1974

Hex

azin

one

[ISO

]51

235-

04-2

SH

416

90H

ydra

met

hyln

on67

485-

29-4

SI

412

00Im

azal

il [I

SO]

3555

4-44

-025

88S

F3

227

ICSC

130

3; JM

PR 2

001,

200

2, 2

006b

Imid

aclo

prid

[ISO

]13

8261

-41-

3S

I4

450

JMPR

200

2; IC

SC 1

501

29

Com

mon

nam

eC

AS

noU

N

noC

hem

ty

pePh

ys

stat

eM

ain

use

GH

SL

D50

m

g/kg

Rem

arks

Imin

octa

dine

[ISO

]13

516-

27-3

SF

330

0Ey

e irr

itant

Indo

xaca

rb [I

SO]

1735

84-4

4-6

SI

326

8JM

PR 2

006b

; LD

50 a

pplie

s to

3:1

mix

ture

of i

som

ers i

n co

mm

erci

al

use

Ioxy

nil [

ISO

]16

89-8

3-4

2588

SH

311

0IC

SC 9

00Io

xyni

l oct

anoa

te [(

ISO

)]38

61-4

7-0

SH

439

0Ip

robe

nfos

2608

7-47

-8S

F4

600

Isop

roca

rb [I

SO]

2631

-40-

527

57C

SI

440

3Is

opro

thio

lane

[ISO

]50

512-

35-1

SF

411

90Is

opro

turo

n [I

SO]

3412

3-59

-6S

H4

1800

Isou

ron

[ISO

]55

861-

78-4

SH

463

0La

mbd

a-cy

halo

thrin

2164

-08-

133

49PY

SI

3c5

6Se

e no

te 9

, p. 8

; EH

C 1

42; H

SG 3

8; J

MPR

200

9b; I

CSC

859

MC

PA [I

SO]

94-7

4-6

PAA

SH

470

0IA

RC

30,

41;

ICSC

54

MC

PA-th

ioet

hyl [

ISO

]25

319-

90-8

PAA

SH

479

0M

CPB

[ISO

]94

-81-

5S

H4

680

Mec

opro

p [I

SO]

7085

-19-

0S

H4

930

ICSC

55

Mec

opro

p-P

[ISO

]16

484-

77-8

SH

410

50M

eflui

dide

[ISO

]53

780-

34-0

SH

419

20M

epiq

uat [

ISO

]15

302-

91-7

SPG

R4

1490

Mer

curo

us c

hlor

ide

[C]

1011

2-91

-120

25H

GS

F3

210

See

note

3; I

CSC

984

; CIC

AD 5

0M

etal

axyl

[ISO

]57

837-

19-1

SF

467

0JM

PR 1

983,

200

3bM

etal

dehy

de [I

SO]

108-

62-3

SM

322

7D

S 93

Met

amitr

on [I

SO]

4139

4-05

-2S

H4

1183

ICSC

136

1M

etam

-sod

ium

[(IS

O)]

137-

42-8

2771

SF-

S3

285

Met

cona

zole

[ISO

]12

5116

-23-

6S

F4

660

Met

hacr

ifos [

ISO

]62

610-

77-9

OP

LI

467

8JM

PR 1

991

30

Com

mon

nam

eC

AS

noU

N

noC

hem

ty

pePh

ys

stat

eM

ain

use

GH

SL

D50

m

g/kg

Rem

arks

Met

hasu

lfoca

rb [I

SO]

6695

2-49

-627

57S

F3

112

Met

hyla

rson

ic a

cid

[ISO

]12

4-58

-3A

SS

H4

1800

ICSC

755

; EH

C 2

24M

ethy

l iso

thio

cyan

ate

[ISO

]55

6-61

-625

88S

F-S

372

Skin

and

eye

irrit

ant;

see

note

6M

etol

carb

[ISO

]11

29-4

1-5

CS

I3

268

Met

ribuz

in [I

SO]

2108

7-64

-9S

H4

322

ICSC

516

Mol

inat

e [I

SO]

2212

-67-

1TC

LH

472

0M

yclo

buta

nil

8867

1-89

-0S

F4

1600

JMPR

199

3N

abam

[ISO

]14

2-59

-627

71S

F4

395

Goi

troge

nic

in ra

tsN

aled

[ISO

]30

0-76

-530

18O

PL

I4

430

DS

39; I

CSC

925

2-N

apth

ylox

yace

tic a

cid

[ISO

]12

0-23

-0S

PGR

460

0N

itrap

yrin

[ISO

]19

29-8

2-4

SB

-S4

1072

ICSC

165

8N

uarim

ol [I

SO]

6328

4-71

-9S

F4

1250

Oct

hilin

one

[ISO

]26

530-

20-1

SF

414

70O

xadi

xyl

7773

2-09

-3S

F4

1860

Pacl

obut

razo

l [IS

O]

7673

8-62

-0S

PGR

413

00JM

PR 1

989

Para

quat

[ISO

]19

10-4

2-5

2781

BP

SH

315

0Se

e no

te 7

; DS

4; E

HC

39;

HSG

51;

ICSC

5; J

MPR

198

7a, 2

004

Pebu

late

[ISO

]11

14-7

1-2

TCL

H4

1120

Pend

imet

halin

[ISO

]40

487-

42-1

SH

410

50Pe

rmet

hrin

[ISO

]52

645-

53-1

3352

PYL

I4

c500

See

note

9, p

. 8; D

S 51

; EH

C 9

4; H

SG 3

3; IA

RC

53;

ICSC

312

; JM

PR 2

000

Phen

thoa

te [I

SO]

2597

-03-

730

18O

PL

I4

c400

DS

48; J

MPR

198

5cPh

osal

one

[ISO

]23

10-1

7-0

2783

OP

SI

312

0IC

SC 7

97; J

MPR

199

8b, 2

002

Phos

met

[ISO

]73

2-11

-627

83O

PS

I,AC

311

3IC

SC 5

43; J

MPR

199

9, 2

004

Phox

im [I

SO]

1481

6-18

-3O

PL

I4

D19

75D

S 31

; JEC

FA 2

000a

Pipe

roph

os [I

SO]

2415

1-93

-730

18O

Poi

lH

432

4

31

Com

mon

nam

eC

AS

noU

N

noC

hem

ty

pePh

ys

stat

eM

ain

use

GH

SL

D50

m

g/kg

Rem

arks

Pirim

icar

b [I

SO]

2310

3-98

-227

57C

SA

P3

147

JMPR

198

3, 2

005

Pirim

ipho

s-m

ethy

l [IS

O]

2923

2-93

-7O

PL

I4

1667

DS

49; J

MPR

199

3, 2

008

Pral

leth

rin [I

SO]

2303

1-36

-933

52PY

oil

I4

460

Proc

hlor

az [I

SO]

6774

7-09

-5S

F4

1600

JMPR

198

5aPr

ofen

ofos

[ISO

]41

198-

08-7

3018

OP

LI

435

8JM

PR 1

991,

200

8Pr

opac

hlor

[ISO

]19

18-1

6-7

SH

415

00D

S 78

; EH

C 1

47; H

SG 7

7; JM

PR 2

002

Prop

anil

[ISO

]70

9-98

-8S

H4

c140

0IC

SC 5

52Pr

opic

onaz

ole

[ISO

]60

207-

90-1

LF

415

20JM

PR 1

988,

200

5Pr

opox

ur [I

SO]

114-

26-1

2757

CS

I3

95D

S 25

; IC

SC 1

91; J

MPR

199

0Pr

osul

foca

rb [I

SO]

5288

8-80

-9TC

LH

418

20Pr

othi

ofos

[ISO

]34

643-

46-4

OP

LI

492

5Py

racl

ofos

[ISO

]77

458-

01-6

3018

OP

LI

323

7Py

razo

phos

[ISO

]13

457-

18-6

2784

SF

443

5JM

PR 1

993

Pyra

zoxy

fen

[ISO

]71

561-

11-0

SH

416

44Py

reth

rins [

C]

8003

-34-

7L

I4

500-

1000

See

note

8; D

S 11

; JM

PR 2

000,

200

4; IC

SC 1

475

Pyrid

aben

[ISO

]96

489-

71-3

SA

C4

820

Pyrid

aphe

nthi

on11

9-12

-0O

PS

I4

769

Pyro

quilo

n [I

SO]

5736

9-32

-1S

F4

320

Qui

nalp

hos [

ISO

]13

593-

03-8

2783

OP

SI

362

Qui

nocl

amin

e [I

SO]

2797

-51-

5S

H4

1360

Qui

zalo

fop

7657

8-12

-6S

H4

1670

Qui

zalo

fop-

p-te

fury

l [IS

O]

1197

38-0

6-6

LH

410

12R

oten

one

[C]

83-7

9-4

2588

SI

313

2-15

00Se

e no

te 9

; HSG

73;

ICSC

944

Sim

etry

n [I

SO]

1014

-70-

6T

SH

418

30So

dium

chl

orat

e [I

SO]

7775

-09-

914

95S

H4

1200

ICSC

111

7

32

Com

mon

nam

eC

AS

noU

N

noC

hem

ty

pePh

ys

stat

eM

ain

use

GH

SL

D50

m

g/kg

Rem

arks

Spiro

xam

ine

[ISO

]11

8134

-30-

8L

F4

500

Der

mal

LD

50 1

068

mg/

kg; m

ay c

ause

skin

sens

itisa

tion

Sulfl

uram

id [I

SO]

4151

-50-

2S

I4

543

2,3,

6-TB

A [I

SO]

50-3

1-7

SH

415

00TC

A [I

SO] (

acid

)76

-03-

918

39S

440

0Se

e no

te 5

to T

able

4, p

. 38;

ICSC

586

Tebu

cona

zole

[ISO

]10

7534

-96-

3S

F4

1700

JMPR

199

5bTe

bufe

npyr

ad [I

SO]

1191

68-7

7-3

SM

T4

595

Tebu

thiu

ron

[ISO

]34

014-

18-1

SH

464

4Te

rbum

eton

[ISO

]33

693-

04-8

TS

H4

483

Tetra

cona

zole

[ISO

]11

2281

-77-

3O

ilF

410

31Th

iacl

oprid

1119

88-4

9-9

SI

439

6JM

PR 2

008

Thio

benc

arb

[ISO

]28

249-

77-6

TCL

H4

1300

Thio

cycl

am [I

SO]

3189

5-22

-4S

I4

310

Thio

dica

rb [I

SO]

5966

9-26

-027

57C

SI

366

JMPR

200

1Th

iram

[ISO

]13

7-26

-8S

F4

560

DS

71; E

HC

78;

IAR

C 1

2, 5

3; IC

SC 7

57; J

MPR

199

3; S

ee n

ote

3Tr

alko

xydi

m [I

SO]

8782

0-88

-0S

H4

934

Tral

omet

hrin

6684

1-25

-633

49PY

SI

3c8

5Tr

iadi

mef

on [I

SO]

4312

1-43

-3S

F4

602

JMPR

198

6b, 2

005

Tria

dim

enol

[ISO

]55

219-

65-3

SFS

T4

900

JMPR

199

0, 2

005

Tria

zam

ate

[ISO

]11

2143

-82-

525

88S

AP

350

-100

Tric

hlor

fon

[ISO

]52

-68-

6O

PS

I3

250

DS

27; E

HC

132

; HSG

66;

IAR

C 3

0, S

uppl

7; I

CSC

585

; JM

PR

1979

; JEC

FA 2

000b

, 200

3Tr

iclo

pyr [

ISO

]55

335-

06-3

SH

471

0Tr

icyc

lazo

le [I

SO]

4181

4-78

-2S

F4

305

Trid

emor

ph [I

SO]

8141

2-43

-3O

ilF

465

0Tr

iflum

izol

e99

387-

89-0

SF

469

5IC

SC 1

252

33

Com

mon

nam

eC

AS

noU

N

noC

hem

ty

pePh

ys

stat

eM

ain

use

GH

SL

D50

m

g/kg

Rem

arks

Uni

cona

zole

[ISO

]83

657-

22-1

SPG

R4

1790

XM

C26

55-1

4-3

CS

I4

542

Xyl

ylca

rb24

25-1

0-7

CS

I4

380

Zira

m [I

SO]

137-

30-4

SF

414

00Ir

ritan

t to

skin

; DS

73; E

HC

78;

IAR

C 1

2, 5

3; IC

SC 3

48; J

MPR

19

97b

EHC

= E

nviro

nmen

tal H

ealth

Crit

eria

Mon

ogra

ph; D

S= P

estic

ide D

ata S

heet

; HSG

= H

ealth

and

Safe

ty G

uide

; IA

RC

= IA

RC

Mon

ogra

phs o

n th

e Eva

luat

ion

of C

arci

noge

nic

Ris

ks to

Hum

ans;

ICSC

= In

tern

atio

nal C

hem

ical

Saf

ety

Car

d; JE

CFA

= E

valu

atio

n by

the

Join

t FA

O/W

HO

Exp

ert C

omm

ittee

on

Food

Add

itive

s; JM

PR =

Eva

luat

ion

by

the

Join

t FA

O/W

HO

Mee

ting

on P

estic

ide

Res

idue

s.

Not

es to

Cla

ss II

1.

Ala

chlo

r was

pre

viou

sly

clas

sifie

d as

a C

lass

Ia p

estic

ide

due

to it

s ca

rcin

ogen

icity

in ra

ts. H

owev

er m

echa

nist

ic s

tudi

es h

ave

indi

cate

d th

at tu

mor

s ar

e in

duce

d by

a

mec

hani

sm n

ot re

leva

nt to

hum

ans.

2.

Bio

alle

thrin

, es

biot

hrin

, es

biol

, an

d es

depa

lléth

rine

are

mem

bers

of

a se

ries;

the

ir to

xici

ty v

arie

s co

nsid

erab

ly w

ithin

thi

s se

ries,

acco

rdin

g to

con

cent

ratio

ns o

f is

omer

s.3.

Th

e in

tern

atio

nal t

rade

of c

hlor

dane

, DD

T, G

amm

a-H

CH

(lin

dane

), H

CH

, mer

cury

com

poun

ds a

nd th

iram

is re

gula

ted

by th

e R

otte

rdam

con

vent

ion

on P

rior I

nfor

med

C

onse

nt (s

ee h

ttp://

ww

w.pi

c.in

t/), w

hich

ent

ered

into

forc

e on

24

Febr

uary

200

4. S

ee T

able

7, p

. 51.

4.

The

prod

uctio

n an

d us

e of

chl

orda

ne, D

DT,

Gam

ma-

HC

H (l

inda

ne) a

nd H

CH

(spe

cific

ally

alp

ha-H

CH

and

bet

a-H

CH

) are

stric

tly li

mite

d by

the

Stoc

khol

m c

onve

ntio

n on

per

sist

ent o

rgan

ic p

ollu

tant

s, w

hich

ent

ered

into

forc

e on

17

May

, 200

4 an

d ha

s sub

sequ

ently

bee

n am

ende

d. S

ee h

ttp://

ww

w.po

ps.in

t/.5.

H

CH

: The

LD

50 v

arie

s acc

ordi

ng to

the

mix

ture

of i

som

ers.

The

valu

e sh

own

has b

een

chos

en, a

nd th

e te

chni

cal p

rodu

ct p

lace

d in

Cla

ss II

, as a

resu

lt of

the

cum

ulat

ive

prop

ertie

s of t

he b

eta

isom

er.

6.

The

mel

ting

poin

t of m

ethy

l iso

thio

cyan

ate

(S) i

s 35°

C.

7.

Para

quat

has

serio

us d

elay

ed e

ffect

s if a

bsor

bed.

It is

of r

elat

ivel

y lo

w h

azar

d in

nor

mal

use

but

may

be

fata

l if t

he c

once

ntra

ted

prod

uct i

s tak

en b

y m

outh

or s

prea

d on

th

e sk

in.

8.

Mix

ture

of c

ompo

unds

pre

sent

in P

yret

hrum

cin

erae

foliu

m a

nd o

ther

flow

ers.

9.

Com

poun

ds fr

om ro

ots o

f Der

ris a

nd L

onch

ocar

pus s

pp.

THE

FIN

AL

CLA

SSIF

ICAT

ION

OF

AN

Y P

RO

DU

CT

DEP

END

S O

N IT

S FO

RM

ULA

TIO

NSe

e Pa

ges 7

& 8

, and

the A

nnex

34

Tabl

e 4.

Slig

htly

haz

ardo

us (C

lass

III)

tech

nica

l gra

de a

ctiv

e in

gred

ient

s in

pes

ticid

es

Com

mon

nam

eC

AS

noU

N

noC

hem

ty

pePh

ys

stat

eM

ain

use

GH

SL

D50

m

g/kg

Rem

arks

Ace

toch

lor [

ISO

]34

256-

82-1

LH

529

50A

lloxy

dim

5563

4-91

-8S

H5

2260

Am

mon

ium

sulfa

mat

e77

73-0

6-0

SH

539

00A

ncym

idol

[ISO

]12

771-

68-5

SPG

R5

4500

Asu

lam

[ISO

]33

37-7

1-1

SH

540

00A

trazi

ne [I

SO]

1912

-24-

9T

SH

4c2

000

DS

82; H

SG 4

7; IA

RC

53;

ICSC

99

Baci

llus t

huri

ngie

nsis

(Bt)

6803

8-71

-1S

I5

>400

0EH

C 2

17B

enal

axyl

[ISO

]71

626-

11-4

SF

542

00JM

PR 1

988,

200

6B

enaz

olin

[ISO

]38

13-0

5-6

SH

532

00Ir

ritan

t to

skin

and

eye

sB

enfu

resa

te68

505-

69-1

SH

520

31B

iphe

nyl

92-5

2-4

SF

532

80IC

SC 1

06B

ispy

ribac

1254

01-7

5-4

SH

526

35B

orax

[ISO

]13

03-9

6-4

SF

545

00IC

SC 5

67B

upiri

mat

e [I

SO]

4148

3-43

-6S

F5

c400

0B

upro

fezi

n [I

SO]

6932

7-76

-0S

I5

2200

JMPR

199

2B

utac

hlor

2318

4-66

-9L

H5

3300

But

ylat

e [I

SO]

2008

-41-

5TC

LF

5>4

000

Car

boxi

n [I

SO]

5234

-68-

4S

FST

538

20C

hino

met

hion

at [I

SO]

2439

-01-

2S

AC

,F5

2500

JMPR

198

8C

hlor

idaz

on [I

SO]

1698

-60-

8S

H5

2420

Chl

orim

uron

9928

3-00

-8S

H5

4102

Chl

orpy

rifos

met

hyl [

ISO

]55

98-1

3-0

OP

SI

5>3

000

DS

33; J

MPR

199

3C

hlor

thal

-dim

ethy

l [IS

O]

1861

-32-

1S

H5

>300

0C

hloz

olin

ate

8433

2-86

-5S

F5

>400

0

35

Com

mon

nam

eC

AS

noU

N

noC

hem

ty

pePh

ys

stat

eM

ain

use

GH

SL

D50

m

g/kg

Rem

arks

Cin

met

hylin

8781

8-31

-3L

H5

3960

Clo

fent

ezin

e [I

SO]

7411

5-24

-5S

AC

5>

3200

JMPR

198

7a, 2

006b

Clo

pyra

lid57

754-

85-5

SH

543

00Se

vere

irrit

ant t

o ey

es; I

CSC

443

Cyc

loat

e [I

SO]

1134

-23-

2TC

LH

4>2

000

Cyc

loxy

dim

1012

05-0

2-1

SH

539

00JM

PR 1

993

Cyr

omaz

ine

6621

5-27

-8S

L5

3300

JMPR

199

1D

iafe

nthi

uron

[ISO

]80

060-

09-9

SA

C5

2068

Dic

hlob

enil

[ISO

]11

94-6

5-6

SH

531

60IC

SC 8

67D

ichl

orm

id37

764-

25-3

LH

520

80D

iclo

ran

99-3

0-9

SF

540

00IC

SC 8

71; J

MPR

199

9D

ieth

ylto

luam

ide

[ISO

]13

4-62

-3L

RP

(inse

ct)

4c2

000

DS

80

Difl

uben

zuro

n35

367-

38-5

SL

5>4

640

DS

77, E

HC

184

; HSG

99;

JMPR

200

2D

ifluf

enic

an [I

SO]

8316

4-33

-4S

H4

>200

0D

imef

uron

[ISO

]34

205-

21-5

SH

4>2

000

Dim

etha

met

ryn

[ISO

]22

936-

75-0

TL

H5

3000

Dim

ethi

rimol

5221

-53-

4S

F5

2350

Dim

etho

mor

ph [I

SO]

1104

88-7

0-5

SF

535

00JM

PR 2

009b

Din

itram

ine

[ISO

]29

091-

05-2

SH

530

00D

iuro

n [I

SO]

330-

54-1

SH

534

00D

odem

orph

[ISO

]15

93-7

7-7

LH

545

00Em

pent

hrin

[(1R

) iso

mer

s] [I

SO]

5440

6-48

-3PY

Oil

I5

>228

0Es

proc

arb

[ISO

]85

785-

20-2

TCL

H4

>200

0Sk

in a

nd e

ye ir

ritan

tEt

heph

on16

672-

87-0

SPG

R5

>400

0JM

PR 2

004;

200

3bEt

ridia

zole

[ISO

]25

93-1

5-9

LF

420

00

36

Com

mon

nam

eC

AS

noU

N

noC

hem

ty

pePh

ys

stat

eM

ain

use

GH

SL

D50

m

g/kg

Rem

arks

Fena

rimol

[ISO

]60

168-

88-9

SF

525

00JM

PR 1

996b

Fenb

ucon

azol

e11

4369

-43-

6S

F4

>200

0JM

PR 1

998

Fenb

utat

in o

xide

[ISO

]13

356-

08-6

OT

SM

T5

2630

EHC

15;

JMPR

199

3Fe

npro

pim

orph

6756

4-91

-4oi

lF

535

15JM

PR 1

995b

, 200

2, 2

005

Flam

prop

-M90

134-

59-1

SF

5>3

000

Flua

zifo

p-p-

buty

l [IS

O]

8306

6-88

-0L

H5

2451

Fluf

enox

uron

1014

63-6

9-8

SI

5>3

000

Flur

ochl

orid

one

6121

3-25

-0S

H5

4000

tau-

Fluv

alin

ate

1028

51-0

6-9

PYoi

lI

5>3

000

Skin

and

eye

irrit

ant

Fosa

min

e [I

SO]

2595

4-13

-6O

PS

H5

2400

Gly

phos

ate

[ISO

]10

71-8

3-6

SH

542

30EH

C 1

59, D

S 91

; IC

SC 1

60; J

MPR

198

7aH

alof

enoz

ide

1122

26-6

1-6

SI

528

50H

exac

onaz

ole

7998

3-71

-4S

F5

2180

JMPR

199

1H

ymex

azol

1000

4-44

-1S

FST

539

00Ip

rodi

one

[ISO

]36

734-

19-7

SF

535

00JM

PR 1

996b

Linu

ron

[ISO

]33

0-55

-2S

H5

4000

ICSC

130

0M

alat

hion

[ISO

]12

1-75

-530

82O

PL

I5

c210

0Se

e no

te 1

; DS

29; I

AR

C 3

0; IC

SC 1

72; J

MPR

199

8b,

2004

Met

azac

hlor

6712

9-08

-2S

H5

2150

Met

habe

nzth

iazu

ron

[ISO

]18

691-

97-9

SH

5>2

500

Met

hyld

ymro

n42

609-

73-4

SH

539

48M

etob

rom

uron

[ISO

]30

60-8

9-7

SH

525

00M

etol

achl

or [I

SO]

5121

8-45

-2L

H5

2780

ICSC

136

0M

etox

uron

1993

7-59

-8S

H5

>320

0M

onol

inur

on17

46-8

1-2

SH

522

50IC

SC 1

273

37

Com

mon

nam

eC

AS

noU

N

noC

hem

ty

pePh

ys

stat

eM

ain

use

GH

SL

D50

m

g/kg

Rem

arks

1-N

apht

hyla

cetic

aci

d86

-87-

3S

PGR

5c3

000

N-o

ctyl

bicy

cloh

epte

ne

dica

rbox

imid

e [C

]11

3-48

-4L

SY5

2800

Ofu

race

5881

0-48

-3S

F5

2600

Oxy

carb

oxin

[ISO

]52

59-8

8-1

SF

420

00Pe

ncon

azol

e66

246-

88-6

SF

521

20JM

PR 1

993

2-Ph

enyl

phen

ol [C

]90

-43-

7S

F5

2480

ICSC

669

; IA

RC

30;

JMPR

200

0Pi

mar

icin

7681

-93-

8S

F5

2730

See

note

2Pr

oben

azol

e27

605-

76-1

SF

520

30Pr

omet

on [I

SO]

1610

-18-

0T

SH

529

80Pr

omet

ryn

[ISO

]72

87-1

9-6

TS

H5

3150

Prop

argi

te [I

SO]

2312

-35-

8L

AC

522

00JM

PR 2

000

Pyrid

ate

[ISO

]55

512-

33-9

SH

5c2

000

Pyrif

enox

[ISO

]88

283-

41-4

LF

429

00Py

rimet

hani

l [IS

O]

5311

2-28

-0S

F5

4150

JMPR

200

9bPy

rithi

obac

sodi

um [I

SO]

1233

43-1

6-8

SH

532

00Q

uinc

lora

c84

087-

01-4

SH

526

80R

esm

ethr

in [I

SO]

1045

3-86

-8PY

SI

420

00Se

e no

te 3

; EH

C 9

2, D

S 83

, HSG

25;

ICSC

324

Seth

oxyd

im [I

SO]

7405

1-80

-2L

H5

3200

Spin

osad

[ISO

]16

8316

-95-

8S

I5

3738

For S

pino

syn

A a

nd D

, CA

S nu

mbe

rs a

re 1

3192

9-60

-7 a

nd

1319

29-6

3-0;

JMPR

200

2; IC

SC 1

502

Spiro

tetr

amat

[ISO

]20

3313

-25-

1S

I4

>20

00JM

PR 2

009a

Sulp

hur

7704

-34-

913

50S

F,I

5>3

000

Skin

and

muc

ous m

embr

ane

irrita

nt. S

ee n

ote

4; IC

SC 1

166

TCA

(sod

ium

salt)

[ISO

]65

0-51

-1S

H5

3200

ICSC

113

9; Ir

ritan

t to

skin

and

eye

s: se

e no

te 5

Tem

epho

s [IS

O]

3383

-96-

8O

PL

I5

4000

DS

8; IC

SC 1

99; J

MPR

200

8

38

Com

mon

nam

eC

AS

noU

N

noC

hem

ty

pePh

ys

stat

eM

ain

use

GH

SL

D50

m

g/kg

Rem

arks

Terb

uthy

lazi

ne [I

SO]

5915

-41-

3T

SH

521

60Te

rbut

ryn

[ISO

]88

6-50

-0T

SH

524

00Te

trach

lorv

inph

os [I

SO]

2224

8-79

-9O

PS

I5

4000

Thia

bend

azol

e [I

SO]

148-

79-8

SF

533

30JE

CFA

199

7, 2

002

Thid

iazu

ron

5170

7-55

-2S

PGR

5>4

000

Tri-a

llate

[ISO

]23

03-1

7-5

TCL

H5

2165

HSG

89;

ICSC

201

Trie

tazi

ne [I

SO]

1912

-26-

1T

SH

528

30IC

SC 2

02Tr

itico

nazo

le [I

SO]

1319

83-7

2-7

SF

4>2

000

Und

ecan

-2-o

ne [C

]11

2-12

-9O

ilR

P, (d

ogs,c

ats)

525

00

EHC

= E

nviro

nmen

tal

Hea

lth C

riter

ia M

onog

raph

; D

S =

Pest

icid

e D

ata

Shee

t; H

SG =

Hea

lth a

nd S

afet

y G

uide

; IA

RC

= I

AR

C M

onog

raph

s on

the

Eva

luat

ion

of

Car

cino

geni

c R

isks

to H

uman

s; IC

SC =

Inte

rnat

iona

l Che

mic

al S

afet

y C

ard;

JEC

FA =

Eva

luat

ion

by th

e Jo

int F

AO

/WH

O E

xper

t Com

mitt

ee o

n Fo

od A

dditi

ves;

JMPR

=

Eval

uatio

n by

the

Join

t FA

O/W

HO

Mee

ting

on P

estic

ide

Res

idue

s.

Not

es to

Cla

ss II

I1.

M

alat

hion

: LD

50 v

alue

can

var

y ac

cord

ing

to im

purit

ies.

This

val

ue h

as b

een

adop

ted

for c

lass

ifica

tion

purp

oses

and

is th

at o

f a te

chni

cal p

rodu

ct c

onfo

rmin

g to

WH

O

spec

ifica

tions

.2.

Pi

mar

icin

: ant

ibio

tic, i

dent

ical

with

tenn

ecet

in a

nd n

atam

ycin

.3.

R

esm

ethr

in is

a m

ixtu

re o

f iso

mer

s, th

e tra

ns is

omer

(70-

80%

) als

o be

ing

know

n as

bio

resm

ethr

in a

nd th

e ci

s iso

mer

(20-

30%

) as c

ism

ethr

in. B

iore

smet

hrin

alo

ne is

of

muc

h lo

wer

toxi

city

(ora

l LD

50 >

7000

mg/

kg) a

nd is

the

subj

ect o

f DS

34. I

t app

ears

in T

able

5.

4.

Sulp

hur d

ust c

an sp

onta

neou

sly

igni

te u

nles

s dilu

ted

abou

t 50%

with

iner

t mat

eria

l.5.

TC

A: T

he d

ata

show

n re

fer t

o so

dium

tric

hlor

oace

tic a

cid.

In m

any

coun

tries

, the

sam

e te

rm (T

CA

) ref

ers t

o th

e fr

ee a

cid

(now

acc

epte

d by

ISO

): th

is is

a so

lid w

ith a

n or

al L

D50

of 4

00 m

g/kg

bw

and

if u

sed

as a

pes

ticid

e w

ould

be

plac

ed in

Cla

ss II

. It i

s hig

hly

corr

osiv

e to

skin

.

THE

FIN

AL

CLA

SSIF

ICAT

ION

OF

AN

Y P

RO

DU

CT

DEP

END

S O

N IT

S FO

RM

ULA

TIO

NSe

e Pa

ges 7

& 8

, and

the A

nnex

39

Tabl

e 5.

Tec

hnic

al g

rade

act

ive

ingr

edie

nts

of p

estic

ides

unl

ikel

y to

pre

sent

acu

te h

azar

d in

nor

mal

use

Com

mon

nam

eC

AS

noU

N n

oC

hem

ty

pePh

ys

stat

eM

ain

use

GH

SL

D50

m

g/kg

Rem

arks

Acl

onife

n74

070-

46-5

SH

5>5

000

Acr

inat

hrin

[ISO

]10

1007

-06-

1PY

SM

T5

>500

0Am

inop

yral

id [I

SO]

1501

14-7

1-9

SH

5>

5000

JMPR

200

9bA

mitr

ole

[ISO

]61

-82-

5S

H5

5000

EHC

158

, DS

79; H

SG 8

5; IA

RC

79;

ICSC

631

; JM

PR 1

998b

Ant

hraq

uino

ne84

-65-

1S

RP

(bird

s)5

>500

0IC

SC 1

605

Azi

msu

lfuro

n [I

SO]

1201

62-5

5-2

SH

5>5

000

Azo

xyst

robi

n [I

SO]

1318

60-3

3-8

SF

5>5

000

JMPR

200

9aB

enflu

ralin

[ISO

]18

61-4

0-1

SH

5>1

0000

Ben

omyl

[ISO

]17

804-

35-2

SF

5>1

0000

EHC

148

, DS

87; H

SG 8

1; IC

SC 3

82; J

MPR

199

6b.

See

note

1B

enox

acor

[ISO

]98

730-

04-2

SH

5>5

000

This

mol

ecul

e is

not

an

activ

e su

bsta

nce

as su

ch b

ut is

a

“saf

ener

”B

ensu

lfuro

n-m

ethy

l83

055-

99-6

SH

5>5

000

Bife

naza

te [I

SO]

1498

77-4

1-8

SAC

5>

5000

JMPR

200

8B

ifeno

x [I

SO]

4257

6-02

-3S

H5

>640

0B

iore

smet

hrin

[ISO

]28

434-

01-7

PYL

I5

>700

0D

S 34

; EH

C 9

2; H

SG 2

5; IC

SC 2

29; J

MPR

199

2B

iterta

nol

5517

9-31

-2S

F5

>500

0JM

PR 1

999

Bosc

alid

[ISO

]18

8425

-85-

6S

F5

>50

00JM

PR 2

008

Bro

mac

il [I

SO]

314-

40-9

SH

552

00IC

SC 1

448

Bro

mob

utid

e74

712-

19-9

SH

5>5

000

Bro

mop

ropy

late

[ISO

]18

181-

80-1

SA

C5

>500

0JM

PR 1

994

Cap

tan

[ISO

]13

3-06

-2S

F5

9000

Irrit

ant t

o sk

in; D

S 9;

HSG

50;

IAR

C 3

0, S

uppl

7;

ICSC

120

; JM

PR 1

996b

, 200

5

40

Com

mon

nam

eC

AS

noU

N n

oC

hem

ty

pePh

ys

stat

eM

ain

use

GH

SL

D50

m

g/kg

Rem

arks

Car

bend

azim

[ISO

]10

605-

21-7

SF

5>1

0000

DS

89; E

HC

149

; HSG

82;

ICSC

127

7; JM

PR 1

996b

, 20

06b

Car

beta

mid

e [I

SO]

1611

8-49

-3C

SH

5>1

0000

Car

prop

amid

[ISO

]10

4030

-54-

8L

F5

>500

0C

hlor

ansu

lam

met

hyl

1475

0-35

-4S

H5

>500

0C

hlor

antr

anili

prol

e [I

SO]

5000

08-4

5-7

SI

5>

5000

JMPR

200

9aC

hlor

fluaz

uron

7142

2-67

-8S

IGR

585

00C

hlor

otha

loni

l [IS

O]

1897

-45-

6S

F5

>100

00EH

C 1

83; H

SG 9

8; IA

RC

30;

ICSC

134

; JM

PR 1

993

Chl

orot

olur

on [I

SO]

1554

5-48

-9S

H5

>100

00IC

SC 1

327

Chl

orpr

opha

m [I

SO]

101-

21-3

CS

PGR

5>5

000

IAR

C 1

2; JM

PR 2

001;

ICSC

150

0C

hlor

sulfu

ron

6490

2-72

-3S

H5

5545

Cin

osul

furo

n [I

SO]

9459

3-91

-6S

H5

>500

0C

lom

epro

p84

496-

56-0

SH

5>5

000

Clo

xyfo

nac

3279

1-87

-0PA

AS

PGR

5>5

000

Cry

olite

[C]

1509

6-52

-3S

I5

>100

00C

yclo

prot

hrin

6393

5-38

-6PY

LI

5>5

000

Cyc

losu

lfam

uron

[ISO

(*)]

1368

49-1

5-5

SH

5>5

000

Cyh

alof

op [I

SO]

1220

08-8

5-9

SH

5>5

000

Dai

mur

on42

609-

52-9

SH

5>5

000

Dal

apon

75-9

9-0

SH

593

30D

amin

ozid

e [I

SO]

1596

-84-

5S

H5

8400

JMPR

199

3D

esm

edip

ham

[ISO

]13

684-

56-5

SH

5>9

600

Dic

hlofl

uani

d [I

SO]

1085

-98-

9S

F5

>500

0JM

PR 1

985a

Dic

lom

ezin

e62

865-

36-5

SF

5>1

0000

Dic

losu

lam

[ISO

]14

5701

-21-

9S

H5

>500

0D

ieth

ofen

carb

8713

0-20

-9S

F5

>500

0

41

Com

mon

nam

eC

AS

noU

N n

oC

hem

ty

pePh

ys

stat

eM

ain

use

GH

SL

D50

m

g/kg

Rem

arks

Dik

egul

ac [I

SO]

1846

7-77

-1S

PGR

5>1

0000

Dim

etho

mor

ph [I

SO]

1104

88-7

0-5

SF

5>5

000

Dim

ethy

l pht

hala

te [C

]13

1-11

-3L

RP

(inse

ct)

582

00IC

SC 2

61

Dip

ropy

l iso

cinc

hom

erat

e [C

]37

37-2

2-2

LR

P (fl

y)5

5230

Dith

iopy

r [IS

O]

9788

6-45

-8S

H5

>500

0Et

halfl

ural

in [I

SO]

5528

3-68

-6S

H5

>100

00Et

hirim

ol [I

SO]

2394

7-60

-6S

FST

563

40Et

hofu

mes

ate

[ISO

]26

225-

79-6

SH

5>6

400

Ethy

l but

ylac

etyl

amin

opro

pion

ate

5230

4-36

-6L

RP

(inse

ct)

5>5

000

Etof

enpr

ox80

844-

07-1

SI

5>1

0000

JMPR

199

4Fa

mox

adon

e [I

SO(*

)]13

1807

-57-

3S

F5

>500

0JM

PR 2

004

Fenc

hlor

azol

e [I

SO]

1031

12-3

5-2

SH

5>5

000

Fenc

lorim

3740

-92-

9S

H5

>500

0Fe

nfur

am [I

SO]

2469

1-80

-3S

FST

5>1

0000

Fenh

exam

id [I

SO]

1268

33-1

7-8

SF

5>5

000

JMPR

200

6bFe

noxy

carb

7912

7-80

-3C

SI

5>1

0000

Fenp

iclo

nil

7473

8-17

-3S

FST

5>5

000

Ferb

am [I

SO]

1448

4-64

-1S

F5

>100

00D

S 94

; EH

C 7

8; IA

RC

12,

42;

ICSC

792

; JM

PR

1997

bFl

oras

ulam

1457

01-2

3-1

SH

5>5

000

Fluc

arba

zone

-sod

ium

1812

74-1

7-9

SH

5>

5000

Fluc

yclo

xuro

n [I

SO]

9405

0-52

-9S

AC

5>5

000

Flud

ioxo

nil [

ISO

]13

1341

-86-

1S

F5

>500

0JM

PR 2

006a

Flum

etra

lin62

924-

70-3

SPG

R5

>500

0

42

Com

mon

nam

eC

AS

noU

N n

oC

hem

ty

pePh

ys

stat

eM

ain

use

GH

SL

D50

m

g/kg

Rem

arks

Flum

etsu

lam

[ISO

]98

967-

40-9

SH

5>5

000

Fluo

met

uron

[ISO

]21

64-1

7-2

SH

5>8

000

Flup

ropa

nate

756-

09-2

SH

5>1

0000

Flup

yrsu

lfuro

n [I

SO]

1447

40-5

4-5

SH

5>5

000

Flur

enol

[ISO

]46

7-69

-6S

PGR

5>5

000

Flur

idon

e [I

SO]

5975

6-60

-4S

H5

>100

00Fl

urox

ypyr

6937

7-81

-7S

H5

>500

0Fl

uthi

acet

1492

53-6

5-6

SH

5>5

000

Flut

olan

il66

332-

96-5

SF

5>1

0000

ICSC

126

5; JM

PR 2

003b

Folp

et13

3-07

-3S

F5

>100

00H

SG 7

2; IC

SC 1

56; J

MPR

199

6bFo

sety

l15

845-

66-2

SF

558

00G

ibbe

relli

c ac

id77

-06-

5S

PGR

5>1

0000

Hex

aflum

uron

[ISO

]86

479-

06-3

SI

5>5

000

ICSC

126

6H

exyt

hiaz

ox78

587-

05-0

SA

C5

>500

0JM

PR 1

992,

200

9aH

ydro

pren

e [I

SO]

4120

5-09

-8L

IGR

5>1

0000

2-H

ydro

xyet

hyl o

ctyl

sulp

hide

[C]

3547

-33-

9L

RP

(inse

ct)

585

30

Imaz

amet

habe

nzm

ethy

l [(I

SO)]

8140

5-85

-8S

H5

>500

0Im

azap

yr81

334-

34-1

SH

5>5

000

Irrit

ant t

o ey

esIm

azaq

uin

8133

5-37

-7S

H5

>500

0Im

azet

hapy

r81

335-

77-5

SH

5>5

000

Imib

enco

nazo

le [I

SO]

8659

8-92

-7S

F5

>500

0In

aben

fide

8221

1-24

-3S

PGR

5>1

0000

Ipro

valic

arb

1409

23-1

7-7

SF

5>5

000

Isox

aben

8255

8-50

-7S

H5

>100

00

43

Com

mon

nam

eC

AS

noU

N n

oC

hem

ty

pePh

ys

stat

eM

ain

use

GH

SL

D50

m

g/kg

Rem

arks

Kas

ugam

ycin

1940

8-46

-9S

F5

>100

00Le

naci

l [IS

O]

2164

-08-

1S

H5

>100

00M

alei

c hy

draz

ide

[C]

123-

33-1

SPG

R5

6950

IAR

C 4

, 42;

JMPR

199

7b C

AS1

0071

-13-

3M

anco

zeb

8018

-01-

7S

F5

>800

0Ir

ritan

t to

skin

on

mul

tiple

exp

osur

e; D

S 94

; EH

C 7

8;

ICSC

754

; JM

PR 1

994

Man

dipr

opam

id [I

SO]

3747

26-6

2-2

SF

5>

5000

JMPR

200

9aM

aneb

[ISO

]12

427-

38-2

SF

567

50Ir

ritan

t to

skin

on

mul

tiple

exp

osur

e; D

S 94

; EH

C 7

8;

ICSC

173

; JM

PR 1

994

Mef

enac

et73

250-

68-7

SH

5>5

000

Mep

anip

yrim

[ISO

]11

0235

-47-

7S

F5

>500

0M

epro

nil [

ISO

]55

814-

41-0

SF

5>1

0000

Met

hopr

ene

[ISO

]40

596-

69-8

LIG

R5

>100

00D

S 47

; JM

PR 1

987b

, 200

2M

etho

xych

lor [

ISO

]72

-43-

5O

CS

I5

6000

DS

28; I

AR

C 5

, 20;

ICSC

130

6; JM

PR 1

978

Met

hozy

feno

zide

1610

50-5

8-4

SI

5>5

000

Der

mal

LD

50 >

500

0; JM

PR 2

004

Met

iram

9006

-42-

2S

F5

>100

00JM

PR 1

994

Met

osul

am13

9528

-85-

1S

H5

>500

0M

etsu

lfuro

n m

ethy

l74

223-

64-6

SH

5>5

000

2-(1

-Nap

hthy

l) ac

etam

ide

86-8

6-2

SPG

R5

6400

Nap

ropa

mid

e15

299-

99-7

SH

550

00N

apta

lam

132-

66-1

SPG

R5

8200

Neb

uron

[ISO

]55

5-37

-3S

H5

>100

00N

iclo

sam

ide

[ISO

]50

-65-

7S

M5

5000

DS

63N

icos

ulfu

ron

[ISO

]11

1991

-09-

4S

H5

>500

0Ir

ritan

t to

eyes

Nitr

otha

l-iso

prop

yl [I

SO]

1055

2-74

-6S

F5

6400

Nor

flura

zon

[ISO

]27

314-

13-2

SH

5>8

000

Nov

alur

on [I

SO]

1167

14-4

6-6

SI

5>

5000

JMPR

200

6b

44

Com

mon

nam

eC

AS

noU

N n

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hem

ty

pePh

ys

stat

eM

ain

use

GH

SL

D50

m

g/kg

Rem

arks

Nov

iflum

uron

1214

51-0

2-3

SI

5>5

000

Der

mal

LD

50 >

500

0O

ryza

lin [I

SO]

1904

4-88

-3S

H5

>100

00O

xabe

trini

l74

782-

23-3

SH

5>5

000

Oxa

diaz

on [I

SO]

1966

6-30

-9S

H5

>800

0O

xine

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per [

ISO

]10

380-

28-6

CU

SF

577

92O

xyflu

orfe

n [I

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4287

4-03

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H5

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ncyc

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6606

3-05

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F5

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noxs

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2197

14-9

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SH

5>5

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Der

mal

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500

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8-8

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Phen

med

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m [I

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1368

4-63

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H5

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0Ph

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[ISO

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80-2

PYL

I5

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S 85

; EH

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246

Pipe

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0; JM

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3036

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3280

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199

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009b

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Prop

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8312

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Terb

acil

[ISO

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Tetra

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n [I

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116-

29-0

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47Te

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7696

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Thife

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Thifl

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Der

mal

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l [IS

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2356

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Tioc

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3724

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5047

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PR 1

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b [I

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e [I

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= E

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Crit

eria

Mon

ogra

ph; D

S= P

estic

ide D

ata S

heet

; HSG

= H

ealth

and

Safe

ty G

uide

; IA

RC

= IA

RC

Mon

ogra

phs o

n th

e Eva

luat

ion

of C

arci

noge

nic

Ris

ks to

Hum

ans;

ICSC

= In

tern

atio

nal C

hem

ical

Saf

ety

Car

d; JM

PR =

Eva

luat

ion

by th

e Jo

int F

AO

/WH

O M

eetin

g on

Pes

ticid

e R

esid

ues.

Not

es to

Tab

le 5

1.

The i

nter

natio

nal t

rade

of b

enom

yl is

regu

late

d by

the R

otte

rdam

conv

entio

n on

Prio

r Inf

orm

ed C

onse

nt (s

ee h

ttp://

ww

w.pi

c.in

t/), w

hich

ente

red

into

forc

e on

24 F

ebru

ary

2004

. See

Tab

le 7

, p. 5

1.

THE

FIN

AL

CLA

SSIF

ICAT

ION

OF

AN

Y P

RO

DU

CT

DEP

END

S O

N IT

S FO

RM

ULA

TIO

NSe

e Pa

ges 7

& 8

, and

the A

nnex

47

Acrylonitrile 107-13-1Aldoxycarb 1646-88-4Aldrin1,2 309-00-2Allidochlor 93-71-0Allyxycarb 6392-46-7Amidithion 919-76-6Aminocarb 2032-59-9Anilazine 101-05-3ANTU 86-88-4Aramite 140-57-8Arsenous oxide 1327-53-3Athidathion 19691-80-6Atraton 1610-17-9Aziprotryne 4658-28-0Azothoate 5834-96-8Barban 101-27-9Barium carbonate 513-77-9Benodanil 15310-01-7Benquinox 495-73-8Benzoximate 29104-30-1Benzoylprop-ethyl 33878-50-1Benzthiazuron 1929-88-0Binapacryl1 485-31-4Bis(tributyltin) oxide 56-35-9Bisthiosemi 39603-48-0Bromocyclen 1715-40-8Bromofenoxim 13181-17-4Bromophos 2104-96-3Bromophos-ethyl 4824-78-6Bufencarb 8065-36-9Butacarb 2655-19-8Butam 35256-85-0Butenachlor 87310-56-3Buthidazole 55511-98-3Buthiobate 51308-54-4

Butonate 126-22-7Butopyronoxyl 532-34-3Buturon 3766-60-7Calcium cyanamide 156-62-7Camphechlor1,2 8001-35-2Carbamorph 31848-11-0Carbanolate 671-04-5Carbon disulfide 75-15-0Carbophenothion 786-19-6Chlomethoxyfen 32861-85-1Chloramben 133-90-4Chloraniformethan 20856-57-9Chloranil 118-75-2Chloranocryl 2164-09-2Chlorbenside 103-17-3Chlorbufam 1967-16-4Chlorbicyclen 2550-75-6Chlorbormuron 13360-45-7Chlordecone 143-50-0Chlordimeform1 6164-98-3Chlorfenac 85-34-7Chlorfenethol 80-06-8Chlorfenprop-methyl 14437-17-3Chlorfenson 80-33-1Chlorfensulfide 22274-74-0Chlorflurenol 2536-31-4Chlormebuform 37407-77-5Chlormethiuron 28217-97-2Chlornitrofen 1836-77-7Chlorobenzilate1 510-15-6Chloroneb 2675-77-6Chloropropylate 5836-10-2Chloroxuron 1982-47-4Chlorquinox 3495-42-9Chlorphoxim 14816-20-7

Active ingredient CAS no Active ingredient CAS no

TABLE 6. ACTIVE INGREDIENTS BELIEVED TO BE OBSOLETE OR DISCONTINUED FOR USE AS PESTICIDES

Ingredients discontinued have been identified from the previous edition of this classification, from the Pesticide Manual (Pesticide Manual, 1991, 1994; 1997, 2003), and in some cases from the manufacturer. It is difficult, in some cases, to be sure whether or not all commercial activity in a substance has ceased; some of these materials are known to be still in use for non-agricultural purposes. IPCS will be grateful for details of any materials in this Section, which are still in commercial use. The common name and CAS number are indicated.

48

Chlorthiamid 1918-13-4Chlorthiophos 21923-23-9Cloethocarb 51487-69-5Clofop 26129-32-8Coumachlor 81-82-3Crimidine 535-89-7Credazine 14491-59-9Crotoxyphos 7700-17-6Crufomate 299-86-5Cyanofenphos 13067-93-1Cyanthoate 3734-95-0Cycloheximide 66-81-9Cycluron 2163-69-1Cyometrinil 63278-33-1Cypendazole 28559-00-4Cyprofuram 69581-33-5Cypromid 2759-71-9Delachlor 24353-58-0Demephion-O 682-80-4Demephion-S 2587-90-8Demeton-O 298-03-3Demeton-S 126-75-0Demeton-S-methylsulphon 17040-19-6Desmetryn 1014-69-3Dialifos 10311-84-9Di-allate 2303-16-4Diamidafos 1754-58-1Dibromochloropropane 96-12-8Dibutyl phthalate 84-74-2Dibutyl succinate 141-03-7Dichlofenthion 97-17-61,2-Dichloropropane 78-87-5Dichlozoline 24201-58-9Diclobutrazol 75736-33-3Dieldrin1,2 60-57-1Dienochlor 2227-47-0Diethatyl 38727-55-8Difenoxuron 14214-32-5Dimefox 115-26-4Dimethirimol 5221-53-4Dimetilan 644-64-4Dimexano 1468-37-7

Dinex 131-89-5Dinocton 32534-96-6Dinoseb1 88-85-7Dinoseb acetate1 2813-95-8Dioxabenzophos 3811-49-2Dioxacarb 6988-21-2Dioxathion 78-34-2Dipropetryn 4147-51-7Disul 149-26-8Ditalimfos 5131-24-8Drazoxolon 5707-69-7Eglinazine 6616-80-4Endothion 2778-04-3Endrin2 72-20-8EPBP 3792-59-4Erbon 136-25-4ESP (Oxydeprofos) 2674-91-1Etacelasil 37894-46-5Etaconazole 60207-93-4Ethidimuron 30043-49-3Ethiolate 2941-55-1Ethirimol 23947-60-6Ethoate-methyl 116-01-8Ethohexadiol 94-96-2Ethyleneglycol bis (trichloroacetate) 2514-53-6

Etrimfos 38260-54-7EXD 502-55-6Fenaminosulf 140-56-7Fenazaflor 14255-88-0Fenchlorphos 299-84-3Fenitropan 65934-95-4Fenoprop (Silvex) 93-72-1Fenoxaprop-ethyl 82110-72-3Fenson 80-38-6Fensulfothion 115-90-2Fenthiaprop 95721-12-3Fenuron 101-42-8Fenuron-TCA 4482-55-7Flamprop 58667-63-3Fluazifop 69335-91-7Flubenzimine 37893-02-0

Active ingredient CAS no Active ingredient CAS no

TABLE 6. ACTIVE INGREDIENTS BELIEVED TO BE OBSOLETE OR DISCONTINUED FOR USE AS PESTICIDES, continued

49

Fluenetil 4301-50-2Fluorodifen 15457-05-3Fluoromide 13577-71-4Fluotrimazole 31251-03-3Fluvalinate 69409-94-5Fonofos 944-22-9Formothion 2540-82-1Fosmethilan 83733-82-8Fosthietan 21548-32-3Furconazole-cis 112839-32-4Furmecyclox 60568-05-0Glyodin 556-22-9Glyphosine 2439-99-8Griseofulvin 126-07-8Halacrinate 34462-96-9Haloxydine 2693-61-0Heptachlor1,2 76-44-8Heptopargil 73886-28-9Hexachloroacetone 116-16-5Hexaflurate 17029-22-0Hydroxyquinoline sulfate 134-31-6Ipazine 1912-25-0IPSP 5827-05-4Isazofos 42509-80-8Isobenzan 297-78-9Isobornyl thiocyano acetate 115-31-1Isocarbamid 30979-48-7Isocil 314-42-1Isodrin 465-73-6Isofenphos 25311-71-1Isomethiozin 57052-04-7Isonoruron 28805-78-9Isopropalin 33820-53-0Isothioate 36614-38-7Isoxapyrifop 87757-18-4Jodfenphos 18181-70-9Karbutilate 4849-32-5Kelevan 4234-79-1Kinoprene 42588-37-4Leptophos 21609-90-5Lythidathion 2669-32-1

Malonoben 10537-47-0Mebenil 7055-03-0Mecarbinzid 27386-64-7Mecarphon 29173-31-7Medinoterb acetate 2487-01-6Menazon 78-57-9Mephospholan 950-10-7Methazole 20354-26-1Methiuron 21540-35-2Methoprotryne 841-06-5Methoxyethylmercury silicate1 64491-92-5

Methoxyphenone 41295-28-7Methoxymethyl mercurychloride1 123-88-6

Methylmercury dicyan-diamide1 502-39-6

Metobromuron 3060-89-7Metsulfovax 21542-18-6Mexacarbate 315-18-4Mipafox 371-86-8Mirex2 2385-85-5Monalide 7187-36-7Monuron 150-68-5Monuron-TCA 140-41-0Morfamquat 4636-83-3Myclozolin 54864-61-8Naphthalene 91-20-3Naphthalic anhydride 81-84-5Nitralin 4726-14-1Nitrilacarb 29672-19-3Nitrofen 1836-75-5Norbormide 991-42-4Noruron 2163-79-3Oxapyrazon 4489-31-0Oxydisulfoton 2497-07-6Parafluron 7159-99-1Perfluidone 37924-13-3Phenisopham 57375-63-0Phenkapton 2275-14-1Phenobenzuron 3134-12-1

Active ingredient CAS no Active ingredient CAS no

TABLE 6. ACTIVE INGREDIENTS BELIEVED TO BE OBSOLETE OR DISCONTINUED FOR USE AS PESTICIDES, continued

50

1 The international trade of aldrin, binapacryl, camphechlor (toxaphene), chlordimeform, chlorobenzilate, dieldrin, dinoseb and dinoseb salts, heptachlor, mercury compounds, and 2,4,5-T is regulated by the Rotterdam convention on Prior Informed Consent (see http://www.pic.int/), which entered into force on 24 February 2004, with subsequent amendments. See Table 7, p. 51.

2 The use and production of aldrin, camphechlor (toxaphene), chlordecone, dieldrin, endrin, heptachlor and mirex is prohibited or severely restricted by the Stockholm convention on persistent organic pollutants, which entered into force on 17 May, 2004, with subsequent amendments. See http://www.pops.int/

Phenylmercurydimethyl-dithiocarbamate1 32407-99-1

Phenylmercury nitrate1 8003-05-2Phosacetim 4104-14-7Phosdiphen 36519-00-3Phosfolan 947-02-4Pindone 83-26-1Piproctanyl 69309-47-3Pirimiphos-ethyl 23505-41-1Potassium cyanate 590-28-3Profluralin 26399-36-0Proglinazine 68228-20-6Promacyl 34264-24-9Promecarb 2631-37-0Propaphos 7292-16-2Propyl isome 83-59-0Prothiocarb 19622-08-3Prothoate 2275-18-5Proxan 108-25-8Pydanon 22571-07-9Pyracarbolid 24691-76-7Pyridinitril 1086-02-8Quinacetol sulfate 57130-91-3Quinonamid 27541-88-4Ryania 8047-13-0Sabadilla 8051-02-3Salicylanilide 87-17-2Schradan 152-16-9Scilliroside 507-60-8

Secbumeton 26259-45-0Sesamex 51-14-9Sodium fluoride 7681-49-4Sodium hexafluorosilicate 16893-85-9Sulfallate 95-06-7Sulfoxide 120-62-7Sulprofos 35400-43-2SWEP 1918-18-92,4,5-T1 93-76-5TDE 72-54-8TEPP 107-49-3Terbucarb 1918-11-2Tetrasul 2227-13-6Thiazafluron 25366-23-8Thicyofen 116170-30-0Thionazin 297-97-2Thiophanate 23564-06-9Thioquinox 93-75-4Triamiphos 1031-47-6Triapenthenol 76608-88-3Triarimol 26766-27-8Tricamba 2307-49-5Trichlamide 70193-21-4Trichloronat 327-98-0Tridiphane 58138-08-2Trifenmorph 1420-06-3Trimethacarb 12407-86-2Vernolate 1929-77-7

Active ingredient CAS no Active ingredient CAS no

TABLE 6. ACTIVE INGREDIENTS BELIEVED TO BE OBSOLETE OR DISCONTINUED FOR USE AS PESTICIDES, continued

51

Table 7. Pesticides subject to the Rotterdam Convention1

Class Pesticide CAS number

O Aldrin2 309-00-2

O Binapacryl 485-31-4

Ia Captafol 2425-06-1

II Chlordane2 57-74-9

O Chlordimeform 6164-98-3

O Chlorobenzilate 510-15-6

II DDT2 50-29-3

1,2-Dibromoethane (EDB) 106-93-4

O Dieldrin2 60-57-1

O Dinoseb and dinoseb salts 88-85-7

Ib DNOC and its salts (such as ammonium salt, potassium salt and sodium salt)

534-52-1; 2980-64-5; 5787-96-2; 2312-76-7

Ethylene dichloride 107-06-2

Ethylene oxide 75-21-8

Ib Fluoroacetamide 640-19-7

II HCH (mixed isomers) 608-73-1

O Heptachlor2 76-44-8

Ia Hexachlorobenzene2 118-74-1

II Lindane2 58-89-9

Mercury compounds, including inorganic mercury compounds, alkyl mercury compounds and alkyloxyalkyl and aryl mercury compounds

Ib Pentachlorophenol 87-86-5

O 2,4,5-T 93-76-5

O Camphechlor (Toxaphene) 8001-35-2

Dustable powder formulations containing a combination of benomyl at or above 7%, carbofuran at above 10%, thiram at or above 15%

17804-35-2; 1563-66-2;

137-26-8

Ib Methamidophos (soluble liquid formulations of the substance that exceed 600 g active ingredient/L)

10265-92-6

Ia Methyl-parathion (emulsifiable concentrates (EC) with 19.5%, 40%, 50%, 60% active ingredient and dusts containing 1.5%, 2% and 3% active ingredient

298-00-0

Ib Monocrotophos (all formulations) 6923-22-4

52

Ia Parathion (all formulations – aerosols, dustable powder (DP), emulsifiable concentrate (EC), granules (GR) and wettable powders (WP) of this substance are included, except capsule suspensions (CS)

56-38-2

Ia Phosphamidon (soluble liquid formulations of the substance that exceed 1000 g active ingredient/L)

13171-21-6 [mixture, (E) & (Z) isomers]

23783-98-4 [(Z)-isomer] 297-99-4 [(E)-isomer]

Tributyltin compounds, including: tributyltin oxide; tributyltin benzoate; tributyltin chloride; tributyltin fluoride; tributyltin linoleate; tributyltin methacrylate; tributyltin naphthenate

1 According to the Rotterdam Convention, export of a chemical can only take place with the prior informed consent of the importing Party. The Prior Informed Consent (PIC) procedure is a means for formally obtaining and disseminating the decisions of importing countries as to whether they wish to receive future shipments of a certain chemical and for ensuring compliance to these decisions by exporting countries. The aim is to promote a shared responsibility between exporting and importing countries in protecting human health and the environment from the harmful effects of such chemicals (further information can be found at: http://www.pic.int/). The Rotterdam Convention (which entered into force on 24 February 2004) built on the voluntary PIC procedure which was initiated by UNEP and FAO in 1989.

2 The use and production of aldrin, chlordane, DDT, dieldrin, heptachlor, hexachlorobenzene and lindane is prohibited or severely restricted by the Stockholm convention on persistent organic pollutants, which entered into force on 17 May, 2004. See http://www.pops.int/

53

TABLE 8. GASEOUS OR VOLATILE FUMIGANTS NOT CLASSIFIED UNDER THE WHO RECOMMENDED CLASSIFICATION OF PESTICIDES BY HAZARD

The Classification does not set out any criteria for air concentrations on which classification could be based. Most of these compounds are of high hazard and recommended exposure limits for occupational exposure have been adopted by national authorities in many countries.

Pesticide CAS number Remarks

Aluminium phosphide 20859-73-8 DS 46; EHC 73; HSG 28; JMPR 1967

Chloropicrin 76-06-2 JMPR 1965b

1,2-Dibromoethane 106-93-4 EHC 177; IARC 15

1,3-Dichloropropene 542-75-6 EHC 146; HSG 76; IARC 41

Ethylene dichloride 107-06-2 EHC 62, 176; HSG 55; IARC 20

Ethylene oxide 75-21-8 EHC 55; HSG 16; JMPR 1969; IARC 11, 36, 42

Formaldehyde 50-00-0 EHC 89; HSG 57

Hydrogen cyanide 74-90-8 JMPR 1965b

Magnesium phosphide 12057-74-8 EHC 73; HSG 28

Methyl bromide 74-83-9 DS 5; EHC 166; HSG 86; IARC 41, 45; JMPR 1967

Phosphine 7803-51-2 DS 46; EHC 73; HSG 28; JMPR 1967

Sulfuryl fluoride 2699-79-8 JMPR 2006b

EHC = Environmental Health Criteria Monograph; DS = Pesticide Data Sheet; HSG = Health and Safety Guide; IARC = IARC Monographs on the Evaluation of Carcinogenic Risks to Humans; ICSC = International Chemical Safety Card; JMPR = Evaluation by the Joint FAO/WHO Meeting on Pesticide Residues.

54

ANNEX

HOW TO FIND THE HAZARD CLASS OF A FORMULATION

The following tables A and B can be used to find the hazard class of a formulation. These should be used only if toxicity data is not available on the formulation itself; see the note at the top of page 7.

The tables should be used as follows:

Step 1: What is the approved name of the active ingredient in the pesticide? Use the index to find the entry in tables 1-5 of the Guidelines.

Step 2: From the entry in the Guidelines, what is the route of application used for the classification?

If the route is O (oral), use table A of this Annex. The same table is used for solids and liquids.

If the route is D (dermal), use table B of this Annex. The same table is used for solids and liquids.

Step 3: From the entry in the Guidelines, what is the LD50 of the active ingredient?

Using the table A or B, selected in Step 2, find the column along the top line which most nearly includes the LD50 figure.

Step 4: What is the concentration % of the active ingredient in the formulation?

Using the same table A or B, find the figure in the left hand column which most nearly includes this percentage figure.

Step 5: Find the square where the column selected in Step 3 crosses the line selected in Step 4. The number in this square is the approximate LD50 of the formulation.

Step 6: The hazard classes are shown by blocks of squares. The hazard class of the formulation is that of the block in which lies the square selected in Step 5.

These tables can also be used to find the hazard class of mixtures. First see page 7, para. 4 of the Guidelines and select the method to be used to arrive at the LD50 of the mixture. For method (b), use the above method from Step 1, using the name of the more or most toxic ingredient. For method (c), pass to Step 4 using the total percentages of all active ingredients in the mixture.

Tabl

e A

. LD

50 v

alue

s an

d cl

assi

ficat

ion

of fo

rmul

atio

ns w

hen

the

rout

e is

OR

AL

Firs

t row

= O

ral L

D50

of t

he a

ctiv

e in

gred

ient

Firs

t col

umn

= Pe

rcen

t con

cent

ratio

n of

the

activ

e in

gred

ient

in th

e fo

rmul

atio

n

C

lass

IaC

lass

IbC

lass

IIC

lass

III

13

510

1520

2530

3540

4550

6080

100

120

140

160

180

200

250

300

350

400

500

600

700

800

900

1000

1500

2000

2500

3000

3500

4000

4500

5000

100

13

510

1520

2530

3540

4550

6080

100

120

140

160

180

200

250

300

350

400

500

600

700

800

900

1000

1500

2000

2500

3000

3500

4000

4500

5000

951

35

1116

2126

3237

4247

5363

8410

512

614

716

818

921

126

331

636

842

152

663

273

784

294

710

5315

7921

0526

3231

5836

8442

1147

3790

13

611

1722

2833

3944

5056

6789

111

133

156

178

200

222

278

333

389

444

556

667

778

889

1000

1111

1667

2222

2778

3333

3889

4444

5000

851

46

1218

2429

3541

4753

5971

9411

814

116

518

821

223

529

435

341

247

158

870

682

494

110

5911

7617

6523

5329

4135

2941

1847

0680

14

613

1925

3138

4450

5663

7510

012

515

017

520

022

525

031

337

543

850

062

575

087

510

0011

2512

5018

7525

0031

2537

5043

7550

0075

14

713

2027

3340

4753

6067

8010

713

316

018

721

324

026

733

340

046

753

366

780

093

310

6712

0013

3320

0026

6733

3340

0046

6770

14

714

2129

3643

5057

6471

8611

414

317

120

022

925

728

635

742

950

057

171

485

710

0011

4312

8614

2921

4328

5735

7142

8650

0065

25

815

2331

3846

5462

6977

9212

315

418

521

524

627

730

838

546

253

861

576

992

310

7712

3113

8515

3823

0830

7738

4646

1560

25

817

2533

4250

5867

7583

100

133

167

200

233

267

300

333

417

500

583

667

833

1000

1167

1333

1500

1667

2500

3333

4167

5000

552

59

1827

3645

5564

7382

9110

914

518

221

825

529

132

736

445

554

563

672

790

910

9112

7314

5516

3618

1827

2736

3645

4550

26

1020

3040

5060

7080

9010

012

016

020

024

028

032

036

040

050

060

070

080

010

0012

0014

0016

0018

0020

0030

0040

0050

0045

27

1122

3344

5667

7889

100

111

133

178

222

267

311

356

400

444

556

667

778

889

1111

1333

1556

1778

2000

2222

3333

4444

403

813

2538

5063

7588

100

113

125

150

200

250

300

350

400

450

500

625

750

875

1000

1250

1500

1750

2000

2250

2500

3750

5000

353

914

2943

5771

8610

011

412

914

317

122

928

634

340

045

751

457

171

485

710

0011

4314

2917

1420

0022

8625

7128

5742

8630

310

1733

5067

8310

011

713

315

016

720

026

733

340

046

753

360

066

783

310

0011

6713

3316

6720

0023

3326

6730

0033

3350

0025

412

2040

6080

100

120

140

160

180

200

240

320

400

480

560

640

720

800

1000

1200

1400

1600

2000

2400

2800

3200

3600

4000

UN

LIK

ELY

205

1525

5075

100

125

150

175

200

225

250

300

400

500

600

700

800

900

1000

1250

1500

1750

2000

2500

3000

3500

4000

4500

5000

157

2033

6710

013

316

720

023

326

730

033

340

053

366

780

093

310

6712

0013

3316

6720

0023

3326

6733

3340

0046

67TO

PR

ESEN

T10

1030

5010

015

020

025

030

035

040

045

050

060

080

010

0012

0014

0016

0018

0020

0025

0030

0035

0040

0050

005

2060

100

200

300

400

500

600

700

800

900

1000

1200

1600

2000

2400

2800

3200

3600

4000

5000

AC

UTE

HA

ZA

RD

333

100

167

333

500

667

833

1000

1167

1333

1500

1667

2000

2667

3333

4000

4667

110

030

050

010

0015

0020

0025

0030

0035

0040

0045

0050

00IN

NO

RM

AL

US

E0.

520

060

010

0020

0030

0040

0050

000.

333

310

0016

6733

3350

000.

110

0030

0050

000.

0520

00

Tabl

e B

. LD

50 v

alue

s an

d cl

assi

ficat

ion

of fo

rmul

atio

ns w

hen

the

rout

e is

DER

MA

L

Firs

t row

= D

erm

al L

D50

of t

he a

ctiv

e in

gred

ient

Firs

t col

umn

= Pe

rcen

t con

cent

ratio

n of

the

activ

e in

gred

ient

in th

e fo

rmul

atio

n

C

lass

IaC

lass

IbC

lass

IIC

lass

III

15

1020

3040

5060

7080

9010

012

014

016

018

020

025

030

035

040

045

050

060

070

080

090

010

0015

0020

0025

0030

0035

0040

0045

0050

0010

01

510

2030

4050

6070

8090

100

120

140

160

180

200

250

300

350

400

450

500

600

700

800

900

1000

1500

2000

2500

3000

3500

4000

4500

5000

951

511

2132

4253

6374

8495

105

126

147

168

189

211

263

316

368

421

474

526

632

737

842

947

1053

1579

2105

2632

3158

3684

4211

4737

901

611

2233

4456

6778

8910

011

113

315

617

820

022

227

833

338

944

450

055

666

777

888

910

0011

1116

6722

2227

7833

3338

8944

4450

0085

16

1224

3547

5971

8294

106

118

141

165

188

212

235

294

353

412

471

529

588

706

824

941

1059

1176

1765

2353

2941

3529

4118

4706

801

613

2538

5063

7588

100

113

125

150

175

200

225

250

313

375

438

500

563

625

750

875

1000

1125

1250

1875

2500

3125

3750

4375

5000

751

713

2740

5367

8093

107

120

133

160

187

213

240

267

333

400

467

533

600

667

800

933

1067

1200

1333

2000

2667

3333

4000

4667

701

714

2943

5771

8610

011

412

914

317

120

022

925

728

635

742

950

057

164

371

485

710

0011

4312

8614

2921

4328

5735

7142

8650

0065

28

1531

4662

7792

108

123

138

154

185

215

246

277

308

385

462

538

615

692

769

923

1077

1231

1385

1538

2308

3077

3846

4615

602

817

3350

6783

100

117

133

150

167

200

233

267

300

333

417

500

583

667

750

833

1000

1167

1333

1500

1667

2500

3333

4167

5000

552

918

3655

7391

109

127

145

164

182

218

255

291

327

364

455

545

636

727

818

909

1091

1273

1455

1636

1818

2727

3636

4545

502

1020

4060

8010

012

014

016

018

020

024

028

032

036

040

050

060

070

080

090

010

0012

0014

0016

0018

0020

0030

0040

0050

0045

211

2244

6789

111

133

156

178

200

222

267

311

356

400

444

556

667

778

889

1000

1111

1333

1556

1778

2000

2222

3333

4444

403

1325

5075

100

125

150

175

200

225

250

300

350

400

450

500

625

750

875

1000

1125

1250

1500

1750

2000

2250

2500

3750

5000

UN

LIK

ELY

353

1429

5786

114

143

171

200

229

257

286

343

400

457

514

571

714

857

1000

1143

1286

1429

1714

2000

2286

2571

2857

4286

303

1733

6710

013

316

720

023

326

730

033

340

046

753

360

066

783

310

0011

6713

3315

0016

6720

0023

3326

6730

0033

3350

0025

420

4080

120

160

200

240

280

320

360

400

480

560

640

720

800

1000

1200

1400

1600

1800

2000

2400

2800

3200

3600

4000

TO P

RES

ENT

205

2550

100

150

200

250

300

350

400

450

500

600

700

800

900

1000

1250

1500

1750

2000

2250

2500

3000

3500

4000

4500

5000

157

3367

133

200

267

333

400

467

533

600

667

800

933

1067

1200

1333

1667

2000

2333

2667

3000

3333

4000

4667

1010

5010

020

030

040

050

060

070

080

090

010

0012

0014

0016

0018

0020

0025

0030

0035

0040

0045

0050

00A

CU

TE H

AZ

AR

D5

2010

020

040

060

080

010

0012

0014

0016

0018

0020

0024

0028

0032

0036

0040

0050

003

3316

733

366

710

0013

3316

6720

0023

3326

6730

0033

3340

0046

671

100

500

1000

2000

3000

4000

5000

IN N

OR

MA

L U

SE

0.5

200

1000

2000

4000

0.3

333

1667

3333

0.1

1000

5000

57

50-00-0 FM 5350-29-3 II 26, 5150-31-7 II 3250-65-7 U 4351-03-6 U 4452-51-7 II 2452-68-6 II 3252-85-7 Ib 2254-11-5 Ib 2255-38-9 II 2756-35-9 O 4756-38-2 Ia 20, 5256-72-4 Ib 2157-24-9 Ib 2357-74-9 II 25, 5158-89-9 II 28, 5160-51-5 II 2760-57-1 O 48, 5161-82-5 U 3962-38-4 Ia 20, 5162-73-7 Ib 2162-74-8 Ia 2063-25-2 II 2566-81-9 O 4872-20-8 O 4872-43-5 U 4372-54-8 O 5074-83-9 FM 5374-90-8 FM 5375-15-0 O 4775-21-8 FM 51, 5375-60-5 II 2775-99-0 U 4076-03-9 II 3276-06-2 FM 5376-44-8 O 49, 5176-87-9 II 2877-06-5 U 4178-34-2 O 4878-57-9 O 49

78-87-5 O 4879-11-8 III 3480-06-8 O 4780-33-1 O 4780-38-6 O 4881-81-2 Ib 2381-82-3 O 4881-84-5 O 4982-66-6 Ia 1982-68-8 U 4583-26-1 O 5083-59-0 O 5083-79-4 II 3184-65-1 U 3984-74-2 O 4885-34-7 O 4786-50-0 Ib 2186-86-2 U 4386-87-3 III 3786-88-4 O 4787-17-2 O 5087-86-5 Ib 22, 5188-85-7 O 48, 5190-43-7 III 3791-20-3 O 4992-52-4 III 3493-71-0 O 4793-72-1 O 4893-75-4 O 5093-76-5 O 50, 5194-74-6 II 2994-75-7 II 2694-81-5 II 2994-82-6 II 2694-96-2 O 4895-06-7 O 5096-12-8 O 4896-24-2 Ib 2197-17-6 O 4897-23-4 II 26

99-30-9 III 35101-05-3 O 47101-21-3 U 40101-27-9 O 47101-42-8 O 48103-17-3 O 47106-46-7 II 26107-02-8 Ib 21107-06-2 FM 51, 53107-13-1 O 47107-18-6 Ib 21107-49-3 O 50108-25-8 O 50108-62-3 II 29112-12-9 III 38113-48-4 III 37114-26-1 II 31115-26-4 O 48115-29-7 II 27115-31-1 O 49115-32-2 II 26115-78-6 II 25115-90-2 O 48116-01-8 O 48116-06-3 Ia 19116-16-5 O 49116-29-0 U 45117-18-0 U 45118-74-1 Ia 19, 51118-75-2 O 47119-12-0 II 31120-23-0 II 30120-62-7 O 50121-75-5 III 36122-14-5 II 27122-34-9 U 45122-42-9 U 44122-88-3 III 35123-33-1 U 43123-88-6 O 49, 51

Pesticide active ingredients, which occur in Tables 1-8, in CAS no order

For each active ingredient, the classification (Ia, Ib, II, III, or U (unlikely to pose an acute hazard in normal use, O (obsolete), FM (fumigant), and page number(s) are given.

CAS no Class Page CAS no Class Page CAS no Class Page

58

124-58-3 II 30125-67-9 II 27126-07-8 O 49126-22-7 O 47126-75-0 O 48131-11-3 U 41131-89-5 O 48132-66-1 U 43133-06-2 U 39133-07-3 U 42133-90-4 O 47134-31-6 O 49134-62-3 III 35136-25-4 O 48137-26-8 II 32, 51137-30-4 II 33137-42-8 II 29139-40-2 U 44140-41-0 O 49140-56-7 O 48140-57-8 O 47141-03-7 O 48141-66-2 Ib 21142-59-6 II 30143-33-9 Ib 23143-50-0 O 47148-79-8 III 38149-26-8 O 48150-68-5 O 49152-16-9 O 50156-62-7 O 47297-78-9 O 49297-97-2 O 50297-99-4 Ia 20, 52298-00-0 Ia 19, 51298-02-2 Ia 20298-03-3 O 48298-04-4 Ia 19299-84-3 O 48299-86-5 O 48

300-76-5 II 30301-12-2 Ib 22309-00-2 O 47, 51314-40-9 U 39314-42-1 O 49315-18-4 O 49327-98-0 O 50330-54-1 III 35330-55-2 III 36333-41-5 II 26371-86-8 O 49465-73-6 O 49467-69-6 U 42470-90-6 Ib 21485-31-4 O 47, 51495-73-8 O 47502-39-6 O 49, 51502-55-6 O 48507-60-8 O 50510-15-6 O 47, 51513-77-9 O 47532-34-3 O 47533-74-4 II 26534-52-1 Ib 22, 51535-89-7 O 48542-75-6 FM 53555-37-3 U 43556-22-9 O 49556-61-6 II 30563-12-2 II 27584-79-2 II 24584-79-2 II 24590-28-3 O 50592-01-8 Ia 19608-73-1 II 28, 51640-15-3 Ib 23640-19-7 Ib 22, 51644-64-4 O 48650-51-1 III 37671-04-5 O 47

682-80-4 O 48709-98-8 II 31731-27-1 U 46732-11-6 II 30741-58-2 II 24756-09-2 U 42759-94-4 II 27786-19-6 O 47834-12-8 II 24841-06-5 O 49886-50-0 III 38900-95-8 II 27919-76-6 O 47919-86-8 Ib 21944-22-9 O 49947-02-4 O 50950-10-7 O 49950-37-8 Ib 22957-51-7 II 27973-21-7 II 27991-42-4 O 49999-81-5 II 251014-69-3 O 481014-70-6 II 311031-47-6 O 501071-83-6 III 361085-98-9 U 401086-02-8 O 501113-02-6 Ib 221114-71-2 II 301129-41-5 II 301134-23-2 III 351194-65-6 III 351303-96-4 III 341314-84-7 Ib 231317-39-1 II 251327-53-3 O 471332-40-7 II 251420-06-3 O 501420-07-1 Ib 21

Pesticide active ingredients, which occur in Tables 1-8, in CAS no order, continued

For each active ingredient, the classification (Ia, Ib, II, III, or U (unlikely to pose an acute hazard in normal use, O (obsolete), FM (fumigant), and page number(s) are given.

CAS no Class Page CAS no Class Page CAS no Class Page

59

1468-37-7 O 481563-66-2 Ib 21, 511582-09-8 U 461593-77-7 U 411596-84-5 U 401610-17-9 O 471610-18-0 III 371646-88-4 O 471689-83-4 II 291689-84-5 II 241698-60-8 III 341715-40-8 O 471746-81-2 III 361754-58-1 O 481836-75-5 O 491836-77-7 O 471861-32-1 III 341861-40-1 U 391897-45-6 U 401910-42-5 II 301912-24-9 III 341912-25-0 O 491912-26-1 III 381918-00-9 II 261918-02-1 U 441918-11-2 O 501918-13-4 O 481918-16-7 II 311929-77-7 O 501929-82-4 II 301929-88-0 O 471967-16-4 O 471982-47-4 O 471982-49-6 U 452008-41-5 III 342032-59-9 O 472032-65-7 Ib 222079-00-7 Ib 212104-64-5 Ia 192104-96-3 O 47

2163-69-1 O 482163-79-3 O 492164-08-1 II 292164-08-1 U 432164-09-2 O 472164-17-2 U 422212-67-1 II 302227-13-6 O 502227-47-0 O 482275-14-1 O 492275-18-5 O 502275-23-2 Ib 232303-16-4 O 482303-17-5 III 382307-49-5 O 502307-68-8 U 442310-17-0 II 302312-35-8 III 372312-76-7 Ib 22, 512385-85-5 O 492425-06-1 Ia 19, 512425-10-7 II 332439-01-2 II 252439-10-3 II 272439-99-8 O 492487-01-6 O 492497-07-6 O 492514-53-6 O 482536-31-4 O 472540-82-1 O 492550-75-6 O 472587-90-8 O 482593-15-9 III 352595-54-2 Ib 222597-03-7 II 302631-37-0 O 502631-40-5 II 292636-26-2 II 252642-71-9 Ib 212655-14-3 II 33

2655-19-8 O 472669-32-1 O 492674-91-1 O 482675-77-6 O 472693-61-0 O 492699-79-8 FM 532759-71-9 O 482764-72-9 II 272778-04-3 O 482797-51-5 II 312813-95-8 O 482921-88-2 II 252980-64-5 Ib 22, 512941-55-1 O 483060-89-7 U 433134-12-1 O 493337-71-1 III 343347-22-6 II 273383-96-8 III 373495-42-9 O 473547-33-9 U 423689-24-5 Ia 203691-35-8 Ia 193734-95-0 O 483737-22-2 U 413740-92-9 U 413766-60-7 O 473766-81-2 II 273792-59-4 O 483811-49-2 O 483813-05-6 III 343861-47-0 II 293878-19-1 II 284104-14-7 O 504147-51-7 O 484151-50-2 II 324234-79-1 O 494301-50-2 O 494482-55-7 O 484489-31-0 O 49

Pesticide active ingredients, which occur in Tables 1-8, in CAS no order, continued

For each active ingredient, the classification (Ia, Ib, II, III, or U (unlikely to pose an acute hazard in normal use, O (obsolete), FM (fumigant), and page number(s) are given.

CAS no Class Page CAS no Class Page CAS no Class Page

60

4636-83-3 O 494658-28-0 O 474726-14-1 O 494824-78-6 O 474849-32-5 O 495131-24-8 O 485221-53-4 III 355234-68-4 III 345259-88-1 III 375598-13-0 III 345707-69-7 O 485787-96-2 Ib 22, 515827-05-4 O 495834-96-8 O 475836-10-2 O 475836-29-3 Ib 215902-51-2 U 455915-41-3 III 386164-98-3 O 47, 516392-46-7 O 476616-80-4 O 486923-22-4 Ib 22, 516988-21-2 O 487055-03-0 O 497085-19-0 II 297159-99-1 O 497187-36-7 O 497287-19-6 III 377292-16-2 O 507446-18-6 Ib 237487-94-7 Ia 197547-66-2 II 267681-49-4 O 507681-93-8 III 377696-12-0 U 457700-17-6 O 487704-34-9 III 377758-98-7 II 257773-06-0 III 347775-09-9 II 31

7778-44-1 Ib 217784-40-9 Ib 227784-46-5 Ib 237803-51-2 FM 538001-35-2 O 47, 518003-05-2 O 50, 518003-34-7 II 318018-01-7 U 438051-02-3 O 508065-36-9 O 479006-42-2 U 4310004-44-1 III 3610071-13-3 U 4310112-91-1 II 29, 5110265-92-6 Ib 22, 5110311-84-9 O 4810380-28-6 U 4410453-86-8 III 3710537-47-0 O 4910552-74-6 U 4310605-21-7 U 4012002-03-8 Ib 2212057-74-8 FM 5312071-83-9 U 4412122-67-7 U 4612407-86-2 O 5012427-38-2 U 4312771-68-5 III 3413067-93-1 O 4813071-79-9 Ia 2013121-70-5 II 2513171-21-6 Ia 20, 5213181-17-4 O 4713194-48-4 Ia 1913356-08-6 III 3613360-45-7 O 4713457-18-6 II 3113516-27-3 II 2913577-71-4 O 4913593-03-8 II 31

13598-36-2 U 4413684-56-5 U 4013684-63-4 U 4413952-84-6 II 2514214-32-5 O 4814255-88-0 O 4814437-17-3 O 4714484-64-1 U 4114491-59-9 O 4814750-35-4 U 4014816-18-3 II 3014816-20-7 O 4715096-52-3 U 4015263-53-3 II 2515299-99-7 U 4315302-91-7 II 2915310-01-7 O 4715457-05-3 O 4915545-48-9 U 4015845-66-2 U 4215879-93-3 II 2515972-60-8 II 2416118-49-3 U 4016484-77-8 II 2916672-87-0 III 3516752-77-5 Ib 2216893-85-9 O 5017029-22-0 O 4917040-19-6 O 4817109-49-8 Ib 2217606-31-4 II 2417804-35-2 U 39, 5118181-70-9 O 4918181-80-1 U 3918467-77-1 U 4118691-97-9 III 3618854-04-8 Ib 2219044-88-3 U 4419408-46-9 U 4319622-08-3 O 50

Pesticide active ingredients, which occur in Tables 1-8, in CAS no order, continued

For each active ingredient, the classification (Ia, Ib, II, III, or U (unlikely to pose an acute hazard in normal use, O (obsolete), FM (fumigant), and page number(s) are given.

CAS no Class Page CAS no Class Page CAS no Class Page

61

19666-30-9 U 4419691-80-6 O 4719937-59-8 III 3620354-26-1 O 4920427-59-2 II 2520856-57-9 O 4720859-73-8 FM 5321087-64-9 II 3021540-35-2 O 4921542-18-6 O 4921548-32-3 O 4921609-90-5 O 4921725-46-2 II 2521908-53-2 Ib 22, 5121923-23-9 O 4822224-92-6 Ib 2222248-79-9 III 3822259-30-9 Ib 2222274-74-0 O 4722571-07-9 O 5022781-23-3 II 2422936-75-0 III 3523031-36-9 II 3123103-98-2 II 3123135-22-0 Ib 2223184-66-9 III 3423505-41-1 O 5023560-59-0 Ib 2223564-05-8 U 4523564-06-9 O 5023783-98-4 Ia 19, 5123947-60-6 III 3523950-58-5 U 4424017-47-8 Ib 2324151-93-7 II 3024201-58-9 O 4824353-58-0 O 4824579-73-5 U 4424691-76-7 O 5024691-80-3 U 41

24934-91-6 Ia 1925057-89-0 II 2425311-71-1 O 4925319-90-8 II 2925366-23-8 O 5025954-13-6 III 3626002-80-2 U 4426087-47-8 II 2926129-32-8 O 4826225-79-6 U 4126259-45-0 O 5026399-36-0 O 5026530-20-1 II 3026644-46-2 U 4626718-65-0 Ia 1926766-27-8 O 5027314-13-2 U 4327355-22-2 U 4427386-64-7 O 4927541-88-4 O 5027605-76-1 III 3728217-97-2 O 4728249-77-6 II 3228434-01-7 U 3928559-00-4 O 4828772-56-7 Ia 1928805-78-9 O 4929091-05-2 III 3529091-21-2 U 4429104-30-1 O 4729173-31-7 O 4929232-93-7 II 3129672-19-3 O 4929973-13-5 Ib 2230043-49-3 O 4830560-19-1 II 2430979-48-7 O 4931218-83-4 Ib 2331251-03-3 O 4931848-11-0 O 47

31895-22-4 II 3232407-99-1 O 50, 5132534-96-6 O 4832791-87-0 U 4032809-16-8 U 4432861-85-1 O 4733089-61-1 II 2433245-39-5 II 2833629-47-9 II 2433693-04-8 II 3233820-53-0 O 4933878-50-1 O 4734014-18-1 II 3234123-59-6 II 2934205-21-5 III 3534256-82-1 III 3434264-24-9 O 5034462-96-9 O 4934643-46-4 II 3134681-10-2 Ib 2134681-23-7 Ib 2135256-85-0 O 4735256-85-0 U 4535367-38-5 III 3535400-43-2 O 5035554-44-0 II 2835575-96-3 II 2436335-67-8 II 2436519-00-3 O 5036614-38-7 O 4936734-19-7 III 3636756-79-3 U 4537248-47-8 U 4637407-77-5 O 4737764-25-3 III 3537893-02-0 O 4837894-46-5 O 4837924-13-3 O 5038260-54-7 O 4838727-55-8 O 48

Pesticide active ingredients, which occur in Tables 1-8, in CAS no order, continued

For each active ingredient, the classification (Ia, Ib, II, III, or U (unlikely to pose an acute hazard in normal use, O (obsolete), FM (fumigant), and page number(s) are given.

CAS no Class Page CAS no Class Page CAS no Class Page

62

39196-18-4 Ib 2339300-45-3 II 2739515-40-7 II 2639603-48-0 O 4740483-25-2 II 2640487-42-1 II 3040596-69-8 U 4341083-11-8 II 2441198-08-7 II 3141205-09-8 U 4241295-28-7 O 49, 5141394-05-2 II 2941483-43-6 III 3441814-78-2 II 3242509-80-8 O 4942576-02-3 U 3942588-37-4 O 4942609-52-9 III 3542609-73-4 U 4342874-03-3 U 4443121-43-3 II 3243222-48-6 II 2650471-44-8 U 4650512-35-1 II 2950563-36-5 II 2650594-66-6 II 2451218-45-2 III 3651218-49-6 U 4451235-04-2 II 2851308-54-4 O 4751487-69-5 O 4851630-58-1 II 2851707-55-2 III 3852304-36-6 U 4152315-07-8 II 2652315-07-8 Ib 2152645-53-1 II 3052888-80-9 II 3152918-63-5 II 2653112-28-0 III 37

53369-07-6 II 2853780-34-0 II 2954406-48-3 III 3554593-83-8 Ia 1954864-61-8 O 4955179-31-2 U 3955219-65-3 II 3255283-68-6 U 4155285-14-8 II 2555290-64-7 II 2655335-06-3 II 3255511-98-3 O 4755512-33-9 III 3755634-91-8 III 3455814-41-0 U 4355861-78-4 II 2956073-07-5 Ia 1956073-10-0 Ia 1956425-91-3 II 2857018-04-9 U 4557052-04-7 O 4957130-91-3 O 5057369-32-1 II 3157375-63-0 O 4957646-30-7 II 2857754-85-5 III 3557837-19-1 II 2957966-95-7 II 2558011-68-0 U 4558138-08-2 O 5058667-63-3 O 4858810-48-3 III 3759669-26-0 II 3259756-60-4 U 4260168-88-9 III 3660207-31-0 II 2460207-90-1 II 3160207-93-4 O 4860568-05-0 O 4961213-25-0 III 36

61432-55-1 II 2662610-77-9 II 2962850-32-2 II 2762865-36-5 U 4062924-70-3 U 4163278-33-1 O 4863284-71-9 II 3063333-35-7 Ia 1963935-38-6 U 4064249-01-0 II 2464257-84-7 II 2764491-92-5 O 4964628-44-0 U 4664902-72-3 U 4065907-30-4 Ib 2265934-95-4 O 4866063-05-6 U 4466215-27-8 III 3566230-04-4 II 2766246-88-6 III 3766332-96-5 U 4266841-25-6 II 3266952-49-6 II 3067129-08-2 III 3667306-00-7 II 2767375-30-8 II 2667485-29-4 II 2867564-91-4 III 3667747-09-5 II 3168038-71-1 III 3468085-85-8 II 2568228-20-6 O 5068359-37-5 Ib 2168505-69-1 III 3469309-47-3 O 5069327-76-0 III 3469335-91-7 O 4869377-81-7 U 4269409-94-5 O 4969581-33-5 O 48

Pesticide active ingredients, which occur in Tables 1-8, in CAS no order, continued

For each active ingredient, the classification (Ia, Ib, II, III, or U (unlikely to pose an acute hazard in normal use, O (obsolete), FM (fumigant), and page number(s) are given.

CAS no Class Page CAS no Class Page CAS no Class Page

63

69806-34-4 II 2870124-77-5 Ib 2270193-21-4 O 5071048-99-2 II 2471422-67-8 U 4071561-11-0 II 3171626-11-4 III 3472178-02-0 II 2873250-68-7 U 4373886-28-9 O 4974051-80-2 III 3774070-46-5 U 3974115-24-5 III 3574223-56-6 U 4574223-64-6 U 4374712-19-9 U 3974738-17-3 U 4174782-23-3 U 4475736-33-3 O 4876578-12-6 II 3176608-88-3 O 5076674-21-0 II 2876738-62-0 II 3077458-01-6 II 3177501-60-1 II 2877732-09-3 II 3078587-05-0 U 4279127-80-3 U 4179277-27-3 U 4579538-32-2 Ib 2379983-71-4 III 3680060-09-9 III 3580844-07-1 U 4181334-34-1 U 4281335-37-7 U 4281335-77-5 U 4281405-85-8 U 4281412-43-3 II 3281777-89-1 II 2582097-50-5 U 46

82110-72-3 O 4882211-24-3 U 4282558-50-7 U 4282560-54-1 II 2482657-04-3 II 2483055-99-6 U 3983066-88-0 III 3683121-18-0 U 4583130-01-2 II 2483164-33-4 III 3583657-22-1 II 3383657-24-3 III 3583733-82-8 O 4984087-01-4 III 3784332-86-5 III 3484496-56-0 U 4085509-19-9 II 2885785-20-2 III 3586479-06-3 U 4286598-92-7 U 4287130-20-9 U 4087310-56-3 O 4787674-68-8 II 2787757-18-4 O 4987818-31-3 II 2587820-88-0 II 3288283-41-4 III 3788485-37-4 II 2888671-89-0 II 3089269-64-7 II 2890035-08-8 Ia 1990134-59-1 III 3690717-03-6 U 4594050-52-9 U 4194361-06-5 II 2694593-91-6 U 4095465-99-9 Ib 2195721-12-3 O 4895737-68-1 U 4596182-53-5 Ia 20

96489-71-3 II 3197886-45-8 U 4198389-04-9 U 4598730-04-2 U 3998967-40-9 U 4299283-00-8 III 3499387-89-0 II 32101007-06-1 U 39101205-02-1 III 35101463-69-8 III 36102851-06-9 III 36103112-35-2 U 41104030-54-8 U 40104653-34-1 Ia 19106040-48-6 U 46107534-96-3 II 32108173-90-6 II 28110235-47-7 U 43110488-70-5 U 41111479-05-1 U 44111991-09-4 U 43111988-49-9 II 32112143-82-5 II 32112226-61-6 III 36112281-77-3 II 32112410-23-8 U 45112839-32-4 O 49113036-87-6 U 44114369-43-6 III 36116170-30-0 O 50116255-48-2 II 24116714-46-6 U 43118134-30-8 II 32118712-89-3 U 46119168-77-3 II 32119446-68-3 II 26119738-06-6 II 31120068-37-3 II 28120162-55-2 U 39120928-09-8 II 27

Pesticide active ingredients, which occur in Tables 1-8, in CAS no order, continued

For each active ingredient, the classification (Ia, Ib, II, III, or U (unlikely to pose an acute hazard in normal use, O (obsolete), FM (fumigant), and page number(s) are given.

CAS no Class Page CAS no Class Page CAS no Class Page

64

121451-02-3 U 44122008-85-9 U 40122453-73-0 II 25122931-48-0 U 45123343-16-8 III 37124495-18-7 U 45125116-23-6 II 29125401-75-4 III 34126535-15-7 U 46126833-17-8 U 41130000-40-7 U 45131341-86-1 U 41131807-57-3 U 41131860-33-8 U 39131929-60-7 U 45

131929-63-0 U 45131983-72-7 III 38134098-61-6 II 27136191-56-5 U 45136849-15-5 U 40138164-12-2 II 24138261-41-3 II 28139528-85-1 U 43140923-17-7 U 42141517-21-7 U 46142459-58-3 II 28144740-54-5 U 42145701-21-9 U 40145701-23-1 U 41149253-65-6 U 42

149877-41-8 U 39150114-71-9 U 39156052-68-5 U 46161050-58-4 U 43168316-95-8 III 37173584-44-6 II 29178928-70-6 U 45181274-17-9 U 41187166-40-1 U 45188425-85-6 U 39203313-25-1 III 37219714-96-2 U 44374726-62-2 U 43500008-45-7 U 40

Pesticide active ingredients, which occur in Tables 1-8, in CAS no order, continued

For each active ingredient, the classification (Ia, Ib, II, III, or U (unlikely to pose an acute hazard in normal use, O (obsolete), FM (fumigant), and page number(s) are given.

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65

Acephate II 24Acetochlor III 34Acifluorfen II 24Aclonifen U 39Acrinathrin U 39Acrolein Ib 21Acrylonitrile O 47Alachlor II 24Alanycarb II 24Aldicarb Ia 19Aldoxycarb O 47Aldrin O 47, 51Allethrin II 24Allidochlor O 47Alloxydim III 34Allyl alcohol Ib 21Allyxycarb O 47Alphachlorohydrin, see

3-Chloro-2,3-propanediol Ib 21

Alpha-cypermethrin II 24Aluminium phosphide FM 53Ametryn II 24Amidithion O 47Aminocarb O 47Aminopyralid U 39Aminotriazole, see Amitrole U 39Amitraz II 24Amitrole U 39Ammonium sulfamate III 34Ancymidol III 34Anilazine O 47Anilofos II 24Anthraquinone U 39ANTU O 47Aramite O 47Arsenous oxide O 47Asulam III 34Athidathion O 47Atraton O 47

Atrazine III 34Azaconazole II 24Azamethiphos II 24Azimsulfuron U 39Azidithion (Menazon) O 47Azinphos-ethyl Ib 21Azinphos-methyl Ib 21Aziprotryne O 47Azocyclotin II 24Azothoate O 47Azoxystrobine U 39Bacillus thuringiensis III 34Barban O 47Barium carbonate O 47Benalaxyl III 34Benazolin III 34Bendiocarb II 24Benefin, see Benfluralin U 39Benfluralin U 39Benfuracarb II 24Benfuresate III 34Benodanil O 47Benomyl U 39, 51Benoxacor U 39Benquinox O 47Bensulfuron-methyl U 39Bensulide II 24Bensultap II 24Bentazone II 24Benthrodine, see Benfluralin U 39Benzamidazole (Isoxaben) U 42Benzofos, see Phosalone II 30Benzoximate O 47Benzoylprop-ethyl O 47Benzthiazuron O 47BHC, see HCH II 28Bifenazate U 39Bifenox U 39Bifenthrin II 24

INDEX. CLASSIFICATION OF ACTIVE PESTICIDE INGREDIENTS

Ia = Extremely hazardous; Ib = Highly hazardous; II = Moderately hazardous;III = slightly hazardous; U = Unlikely to present acute hazard in normal use;FM = Fumigant, not classified; O = Obsolete as pesticide, not classified.

Common name Class Page Common name Class Page

66

Bilanafos II 24Binapacryl O 47, 51Bioallethrin II 24Bioresmethrin U 39Biphenyl III 34Bis(tributyltin) oxide O 47Bispyribac III 34Bisthiosemi O 47Bitertanol U 39Blasticidin-S Ib 21BMPC, see Fenobucarb II 27Borax III 34Boscalid U 39Brodifacoum Ia 19Bromacil U 39Bromadiolone Ia 19Bromethalin Ia 19Bromobutide U 39Bromocyclen O 47Bromofenoxim O 47Bromophos O 47Bromophos-ethyl O 47Bromopropylate U 39Bromoxynil II 24Bromuconazole II 24Bronopol II 24Bufencarb O 47Bupirimate III 34Buprofezin III 34Butacarb O 47Butachlor III 34Butam O 47Butamifos II 24Butenachlor O 47Buthidazole O 47Buthiobate O 47Butocarboxim Ib 21Butonate O 47Butopyronoxyl O 47

Butoxycarboxim Ib 21Butralin II 24Butroxydim II 25Buturon O 47Butylamine II 25Butylate III 34Cacodylic acid, see

Dimethylarsinic acid II 27

Cadusafos Ib 21Calcium arsenate Ib 21Calcium cyanamide O 47Calcium cyanide Ia 19Camphechlor O 47Captafol Ia 19, 51Captan U 39Carbamorph O 47Carbanolate O 47Carbaryl II 25Carbendazim U 40Carbetamide U 40Carbofos, see Malathion III 36Carbofuran Ib 21, 51Carbon disulfide O 47Carbophenothion O 47Carbosulfan II 25Carboxin III 34Carpropamid U 40Cartap II 25Chinomethionat III 34Chlomethoxyfen O 47Chloralose II 25Chloramben O 47Chlorantraniliprole U 40Chloraniformethan O 47Chloranil O 47Chloranocryl O 47Chloransulam methyl U 40Chlorbenside O 47Chlorbicyclen O 47

INDEX. CLASSIFICATION OF ACTIVE PESTICIDE INGREDIENTS, CONTINUED

Ia = Extremely hazardous; Ib = Highly hazardous; II = Moderately hazardous;III = slightly hazardous; U = Unlikely to present acute hazard in normal use;FM = Fumigant, not classified; O = Obsolete as pesticide, not classified.

Common name Class Page Common name Class Page

67

Chlorbromuron O 47Chlorbufam O 47Chlordane II 25, 51Chlordecone O 47Chlordimeform O 47, 51Chlorethoxyfos Ia 19Chlorfenac O 47Chlorfenapyr II 25Chlorfenethol O 47Chlorfenidin (Monuron) O 49Chlorfenprop-methyl O 47Chlorfenson O 47Chlorfensulfide O 47Chlorfenvinphos Ib 21Chlorfluazuron U 40Chlorflurecol, see

Chlorflurenol O 47

Chlorflurenol O 47Chloridazon III 34Chlorimuron III 34Chlormebuform O 47Chlormephos Ia 19Chlormequat (chloride) II 25Chlormethiuron O 47Chlornitrofen O 47Chloroacetic acid II 25Chlorobenzilate O 47, 51Chlorocholine chloride, see

Chlormequat (chloride) II 25

Alphachlorohydrin, see 3-Chloro-2,3-propanediol Ib 21

Chloroneb O 47Chlorophacinone Ia 19Chloropicrin FM 533-Chloro-1,2-propanediol Ib 21Chloropropylate O 47Chlorothalonil U 40Chlorotoluron U 40Chloroxuron O 47

Chlorphenamidine (Chlordimeform) O 47, 51

Chlorphonium chloride O 47Chlorphoxim O 47Chlorpropham U 40Chlorpyrifos II 25Chlorpyrifos methyl III 34Chlorquinox O 47Chlorsulfuron U 40Chlorthal-dimethyl III 34Chlorthiamid O 48Chlorthiophos O 48Chlozolinate III 34Cinmethylin III 35Cinosulfuron U 40Cismethrin, see Resmethrin III 37Citrex, see Dodine II 27Cloethocarb O 48Clofentezine III 35Clofop O 48Clomazone II 25Clomeprop U 40Clonitralide, see Niclosamide U 43Clopyralid III 35Cloxyfonac U 40CNA, see Dicloran III 35COMU (Cycluron) O 48Copper hydroxide II 25Copper oxychloride II 25Copper sulfate II 25Coumachlor O 48Coumaphos Ib 21Coumatetralyl Ib 214-CPA III 35Credazine O 48Crimidine O 48Crotoxyphos O 48Crufomate O 48Cryolite U 40

INDEX. CLASSIFICATION OF ACTIVE PESTICIDE INGREDIENTS, CONTINUED

Ia = Extremely hazardous; Ib = Highly hazardous; II = Moderately hazardous;III = slightly hazardous; U = Unlikely to present acute hazard in normal use;FM = Fumigant, not classified; O = Obsolete as pesticide, not classified.

Common name Class Page Common name Class Page

68

Cuprous oxide II 25CVP, see Chlorfenvinphos Ib 21Cyanazine II 25Cyanofenphos O 48CYAP, see Cyanophos II 25Cyanophos II 25Cyanthoate O 48Cycloate III 35Cycloheximide O 48Cycloprothrin U 40Cyclosulfamuron U 40Cycloxydim III 35Cycluron O 48Cyfluthrin Ib 21Beta-cyfluthrin Ib 21Cyhalofop U 40Cyhalothrin II 25Lambda-cyhalothrin II 25CYP (Cyanofenphos) O 48Cyhexatin II 25Cymoxanil II 25Cyometrinil O 48Cypendazole O 48Cypermethrin II 26Alpha-cypermethrin II 26Cyphenothrin [(1R)-isomers] II 26Cyproconazole II 26Cyprofuram O 48Cypromid O 48Cyromazine III 352,4-D II 26Daimuron U 40Dalapon U 40Daminozide U 40DAPA (Fenaminosulf) O 48Dazomet II 26DBCP

(Dibromochloro propane) O 48

DCBN (Chlorthiamid) O 48

2,4-DB II 26DDT II 26, 51DDVF, see Dichlorvos Ib 21DDVP, see Dichlorvos Ib 21DEET, see Diethyltoluamide III 35Dehydroacetic acid (Disul) O 48Delachlor O 48Delnav (Dioxathion) O 48Deltamethrin II 26Demephion-O O 48Demephion-S O 48Demeton-O O 48Demeton-S O 48Demeton-S-methyl Ib 21Demeton-S-methylsulphon O 482,4-DES (Disul) O 48Desmedipham U 40Desmetryn O 48Diafenthiuron III 35Dialifor (Dialifos) O 48Dialifos O 48Di-allate O 48Diallyldichloroacetamide, see

DichlormidIII 35

Diamidafos O 48Dibrom, See Naled II 30Diazinon II 26Dibromochloropropane O 481,2-Dibromoethane (EDB) FM 51, 53Dibutyl phthalate O 48Dibutyl succinate O 48Dicamba II 26Dichlobenil III 35Dichlofenthion O 48Dichlofluanid U 40Dichlorfenidim, see Diuron III 35Dichlormid III 35Dichlorobenzene II 26Dichlorophen II 26

INDEX. CLASSIFICATION OF ACTIVE PESTICIDE INGREDIENTS, CONTINUED

Ia = Extremely hazardous; Ib = Highly hazardous; II = Moderately hazardous;III = slightly hazardous; U = Unlikely to present acute hazard in normal use;FM = Fumigant, not classified; O = Obsolete as pesticide, not classified.

Common name Class Page Common name Class Page

69

Dichloropicolinic acid, see Clopyralid III 35

1,2-Dichloropropane O 481,3-Dichloropropene FM 51, 53Dichlorprop II 26Dichlorvos Ib 21Dichlozoline O 48Diclobutrazol O 48Diclofop II 26Diclomezine U 40Dicloran III 35Diclosulam U 40Dicofol II 26Dicrotophos Ib 21Dieldrin O 48, 51Dienochlor O 48Diethatyl O 48Diethofencarb U 40Diethyltoluamide III 35Difenacoum Ia 19Difenoconazole II 26Difenoxuron O 48Difenzoquat II 26Difethialone Ia 19Diflubenzuron III 35Diflufenican III 35Difolatan, see Captafol Ia 19, 51Dikegulac U 41Dimefox O 48Dimefuron III 35Dimepiperate II 26Dimethachlor II 26Dimethametryn III 35Dimethenamid II 27Dimethipin II 26Dimethirimol III 35Dimethoate II 27Dimethomorph U 41Dimethyl phthalate U 41

Dimethylarsinic acid II 27Dimetilan O 48Dimexano O 48Dinex O 48Diniconazole II 27Dinitramine III 35Dinobuton II 27Dinocap II 27Dinocton O 48Dinoseb O 48, 51Dinoseb acetate O 48, 51Dinoterb Ib 21Dioxabenzophos O 48Dioxacarb O 48Dioxathion O 48Diphacinone Ia 19Diphenamid II 27Diphenyl, see Biphenyl III 34Dipropetryn O 48Dipropyl isocinchomerate U 41Diquat II 27Disodium octaborate,

see Borax III 34

Disul O 48Disulfoton Ia 19Ditalimfos O 48Dithianon II 27Dithiopyr U 41Diuron III 35DMTP, see Methidathion Ib 22DNBP (Dinoseb) O 48, 51DNBPA (Dinoseb acetate) O 48, 51DNOC Ib 22, 51Dodemorph U 41Dodine II 27Doguanide, see Dodine II 27Drazoxolon O 48DSMA, see

Methylarsonic acid II 30

INDEX. CLASSIFICATION OF ACTIVE PESTICIDE INGREDIENTS, CONTINUED

Ia = Extremely hazardous; Ib = Highly hazardous; II = Moderately hazardous;III = slightly hazardous; U = Unlikely to present acute hazard in normal use;FM = Fumigant, not classified; O = Obsolete as pesticide, not classified.

Common name Class Page Common name Class Page

70

EDDP, see Edifenphos Ib 22Edifenphos Ib 22Eglinazine O 48Empenthrin [(1R) isomers] III 35Endosulfan II 27Endothal-sodium II 27Endothion O 48Endrin O 48EPBP O 48Ephirsulfonate see

Chlorfenson O 47

EPN Ia 19Epoxyethane, see

Ethylene oxide FM 51, 53

EPTC II 27Erbon O 48Esbiol, see Bioallethrin II 24Esbiothrin, see Bioallethrin II 24Esdeballéthrin, see

Bioallethrin II 24

Esfenvalerate II 27ESP (Oxydeprofos) O 48Esprocarb III 35Etacelasil O 48Etaconazole O 48Ethalfluralin U 41Ethephon III 35Ethidimuron O 48Ethiofencarb Ib 22Ethiolate O 48Ethion II 27Ethirimol U 41Ethoate-methyl O 48Ethofumesate U 41Ethohexadiol O 48Ethoprop, see Ethoprophos Ia 19Ethoprophos Ia 19Ethyl butylacetylaminopropionate U 41

Ethylene dichloride FM 51, 53

Ethylene oxide FM 51, 53Ethyleneglycol-

bis(trichloroacetate) O 48

Ethylthiometon, see Disulfoton Ia 19

Etofenprox U 41Etridiazole III 35Etrimfos O 48EXD O 48Famoxadone U 41Famphur Ib 22Fenaminosulf O 48Fenamiphos Ib 22Fenarimol III 36Fenazaflor O 48Fenazaquin II 27Fenbuconazole III 36Fenbutatin oxide III 36Fenchlorazole U 41Fenchlorphos O 48Fenclorim U 41Fenfuram U 41Fenhexamid U 41Fenidim, see Fenuron O 48Fenitropan O 48Fenitrothion II 27Fenobucarb II 27Fenoprop (Silvex) O 48Fenothiocarb II 27Fenoxaprop-ethyl O 48Fenoxycarb U 41Fenpiclonil U 41Fenpropathrin II 27Fenpropidin II 27Fenpropimorph III 36Fenpyroximate II 27Fenson O 48Fensulfothion O 48Fenthiaprop O 48

INDEX. CLASSIFICATION OF ACTIVE PESTICIDE INGREDIENTS, CONTINUED

Ia = Extremely hazardous; Ib = Highly hazardous; II = Moderately hazardous;III = slightly hazardous; U = Unlikely to present acute hazard in normal use;FM = Fumigant, not classified; O = Obsolete as pesticide, not classified.

Common name Class Page Common name Class Page

71

Fenthion II 27Fentin acetate II 27Fentin hydroxide II 28Fenuron O 48Fenuron-TCA O 48Fenvalerate II 28Ferbam U 41Ferimzone II 28Fipronil II 28Flamprop O 48Flamprop-M III 36Flocoumafen Ia 19Florasulam U 41Fluazifop O 48Fluazifop-p-butyl III 36Flubenzimine O 48Flucarbazone-sodium U 41Fluchloralin II 28Flucycloxuron U 41Flucythrinate Ib 22Fludioxinil U 41Fluenetil O 49Flufenacet II 28Flufenoxuron III 36Flumetralin U 41Flumetsulam U 42Fluometuron U 42Fluoroacetamide Ib 22, 51Fluorodifen O 49Fluoroglycofen II 28Fluoromide O 49Fluotrimazole O 49Flupropanate U 42Flupyrsulfuron U 42Flurecol-butyl, see Flurenol U 42Flurenol U 42Fluridone U 42Flurochloridone III 36Fluroxypyr U 42

Flurprimidol II 28Flusilazole II 28Fluthiacet U 42Flutolanil U 42Flutriafol II 28tau-Fluvalinate III 36Fluvalinate O 49Fluxofenim II 28Folpet U 42Fomesafen II 28Fonofos O 49Formaldehyde FM 53Formetanate Ib 22Formothion O 49Fosamine III 36Fosetyl U 42Fosfamid, see Dimethoate II 27Fosmethilan O 49Fosthietan O 49Fuberidazole II 28Furalaxyl II 28Furathiocarb Ib 22Furconazole-cis O 49Furmecyclox O 49Gamma-BHC, see

gammma-HCH II 28, 51

Gamma-HCH II 28, 51Gibberellic acid U 42Glufosinate II 28Glyodin O 49Glyphosate III 36Glyphosine O 49Griseofulvin O 49Guazatine II 28Halacrinate O 49Halofenozide III 36Haloxydine O 49Haloxyfop II 28HCH II 28, 51

INDEX. CLASSIFICATION OF ACTIVE PESTICIDE INGREDIENTS, CONTINUED

Ia = Extremely hazardous; Ib = Highly hazardous; II = Moderately hazardous;III = slightly hazardous; U = Unlikely to present acute hazard in normal use;FM = Fumigant, not classified; O = Obsolete as pesticide, not classified.

Common name Class Page Common name Class Page

72

Heptachlor O 49, 51Heptenophos Ib 22Heptopargil O 49Hexachloroacetone O 49Hexachlorobenzene Ia 19, 51Hexaconazole III 36Hexaflumuron U 42Hexaflurate O 49Hexazinone II 28Hexythiazox U 42Hydramethylnon II 28Hydrogen cyanide FM 53Hydroprene U 422-Hydroxyethyl-octyl sulphide U 42Hydroxyisoxazole, see

HymexazolIII 36

Hydroxyquinolinesulfate O 49Hymexazol III 36Imazalil II 28Imazamethabenzmethyl U 42Imazapyr U 42Imazaquin U 42Imazethapyr U 42Imibenconazole U 42Imidacloprid II 28Iminoctadine II 29Inabenfide U 42Iodofenphos (Jodfenphos) O 49Indoxacarb II 29Ioxynil II 29Ioxynil octanoate II 29Ipazine O 49IBP, see Iprobenfos II 29Iprobenfos II 29Iprodione III 36Iprovalicarb U 42IPSP O 49Isazofos O 49Isobenzan O 49

Isobornyl thiocyanoacetate O 49Isocarbamid O 49Isocil O 49Isodrin O 49Isofenphos O 49Isomethiozin O 49Isonoruron O 49Isoprocarb II 29Isopropalin O 49Isoprothiolane II 29Isoproturon II 29Isothioate O 49Isouron II 29Isoxaben U 42Isoxapyrifop O 49Isoxathion Ib 22Jodfenphos O 49Karbation, see Metam-sodium II 29Karbutilate O 49Kasugamycin U 43Kelevan O 49Keltane, see Dicofol II 26Kinoprene O 49Lambda-cyhalothrin II 29Lead arsenate Ib 22Lenacil U 43Leptophos O 49Lindane, see Gamma-HCH II 28, 51Linuron III 36Lythidathion O 49M74, see Disulfoton Ia 19Magnesium phosphide FM 53Malathion III 36Maldison, see Malathion III 36Maleic hydrazide U 43Malonoben O 49Mancozeb U 43Mandipropamid U 43Maneb U 43

INDEX. CLASSIFICATION OF ACTIVE PESTICIDE INGREDIENTS, CONTINUED

Ia = Extremely hazardous; Ib = Highly hazardous; II = Moderately hazardous;III = slightly hazardous; U = Unlikely to present acute hazard in normal use;FM = Fumigant, not classified; O = Obsolete as pesticide, not classified.

Common name Class Page Common name Class Page

73

MBCP (Leptophos) O 49MCC (SWEP) O 50MCPA II 29MCPA-thioethyl II 29MCPB II 29Mebenil O 49Mecarbam Ib 22Mecarbinzid O 49Mecarphon O 49Mecoprop II 29Mecoprop-P II 29Medinoterb acetate O 49Mefenacet U 43Mefluidide II 29Menazon O 49MEP, see Fenitrothion II 27Mepanipyrim U 43Mephospholan O 49Mepiquat II 29Mepronil U 43Mercapthphos (Demeton-O and Demeton-S ) O 48

Mercaptodimethur, see Methiocarb Ib 22

Mercuric chloride Ia 19, 51Mercuric oxide Ib 22, 51Mercurous chloride II 29, 51Metalaxyl II 29Metaldehyde II 29Metamitron II 29Metam-sodium II 29Metaphos, see

Parathion-methyl Ia 19

Metazachlor III 36Metconazole II 29Methabenzthiazuron III 36Methacrifos II 29Methamidophos Ib 22, 51Methasulfocarb II 30Methazole O 49

Methidathion Ib 22Methiocarb Ib 22Methiuron O 49Methomyl Ib 22Methoprene U 43Methoprotryne O 49Methoxychlor U 43Methoxyethylmercury silicate O 49, 51Methoxymethyl mercury

chloride O 49, 51

Methoxyphenone O 49Methozyfenozide U 43Methyl bromide FM 53Methyl isothiocyanate II 30Methylarsonic acid II 30Methyldymron III 36Methylmercapthphos teolovy,

see Demeton-S-methyl Ib 21

Methylmercury dicyandiamide O 49, 51Methyl-parathion Ia 19, 51Metilmerkaptophosoksid, see

Oxydemeton-methyl Ib 22

Metiram U 43Metobromuron U 43Metolachlor III 36Metolcarb II 30Metosulam U 43Metoxuron III 36Metribuzin II 30Metriltriazotion, see

Azinphos-methyl Ib 21

Metsulfovax O 49Metsulfuron methyl U 43Metsulfuron, see

Metsulfuron methyl U 43

Mevinphos Ia 19Mexacarbate O 49MICP, see Isoprocarb II 29Mipafox O 49Mirex2 O 49

INDEX. CLASSIFICATION OF ACTIVE PESTICIDE INGREDIENTS, CONTINUED

Ia = Extremely hazardous; Ib = Highly hazardous; II = Moderately hazardous;III = slightly hazardous; U = Unlikely to present acute hazard in normal use;FM = Fumigant, not classified; O = Obsolete as pesticide, not classified.

Common name Class Page Common name Class Page

74

Molinate II 30Monalide O 49Monocrotophos Ib 22, 51Monolinuron III 36Monuron O 49Monuron-TCA O 49Morfamquat O 49MPMC, see Xylylcarb II 33MPP, see Fenthion II 27MSMA, see

Methylarsonic acid II 30

Myclobutanil II 30Myclozolin O 49Nabam II 30NAC, see Carbaryl II 25Naled II 30Naphthalene O 49Naphthalic anhydride O 492-(1-Naphthyl) acetamide U 431-Naphthylacetic acid III 37Napropamide U 43Naptalam U 432-Napthyloxyacetic acid II 30Neburon U 43Niclosamide U 43Nicosulfuron U 43Nicotine Ib 22Nitralin O 49Nitrapyrin II 30Nitrilacarb O 49Nitrofen O 49Nitrothal-isopropyl U 43Norbormide O 49Norflurazon U 43Noruron O 49Novaluron U 43Noviflumuron U 44Nuarimol II 30Octhilinone II 30

N-octylbicycloheptene dicarboximide III 37

(Octylthio)ethanol, see 2-Hydroxyethyloctyl sulphide U 42

Ofurace III 37Omethoate Ib 22Oryzalin U 44Oxabetrinil U 44Oxadiazon U 44Oxadixyl II 30Oxamyl Ib 22Oxapyrazon O 49Oxine-copper U 44Oxycarboxin III 37Oxydemeton-methyl Ib 22Oxydisulfoton O 49Oxyfluorfen U 442,4 PA, see 2,4-D II 26Paclobutrazol II 30Palléthrin, see Allethrin II 24PAP, see Phenthoate II 30Paradichlorobenzene, see

Dichlorobenzene II 26

Parafluron O 49Paraquat II 30Parathion Ia 19, 52Parathion-methyl Ia 19, 51Paris green Ib 22Pebulate II 30Penconazole III 37Pencycuron U 44Pendimethalin II 30Penoxsulam U 44Pentachlorophenol Ib 22, 51Pentanochlor U 44Perfluidone O 49Permethrin II 30PHC, see Propoxur II 31Phenisobromolate, see

Bromopropylate U 39

INDEX. CLASSIFICATION OF ACTIVE PESTICIDE INGREDIENTS, CONTINUED

Ia = Extremely hazardous; Ib = Highly hazardous; II = Moderately hazardous;III = slightly hazardous; U = Unlikely to present acute hazard in normal use;FM = Fumigant, not classified; O = Obsolete as pesticide, not classified.

Common name Class Page Common name Class Page

75

Phenisopham O 49Phenkapton O 49Phenmedipham U 44Phenobenzuron O 49Phenothrin U 44Phenthoate II 30Phenylmercury acetate Ia 20, 51Phenylmercury dimethyl-

dithiocarbamate O 50, 51

Phenylmercury nitrate O 50, 512-Phenylphenol III 37Phorate Ia 20Phosacetim O 50Phosalone II 30Phosdiphen O 50Phosfolan O 50Phosmet II 30Phosphamidon Ia 20, 51Phosphine FM 53Phosphorus acid U 44Phoxim II 30Phthalide U 44Phthalofos, see Phosmet II 30Picloram U 44Pimaricin III 37Pindone O 50Piperonyl butoxide U 44Piperophos II 30Piproctanyl O 50Pirimicarb II 31Pirimiphos-ethyl O 50Pirimiphos-methyl II 31Polychlorocamphene

(Camphechlor) O 47, 51

Potassium cyanate O 50Prallethrin II 31Pretilachlor U 44Primisulfuron U 44Probenazole III 37Prochloraz II 31

Procymidone U 44Prodiamine U 44Profenofos II 31Profluralin O 50Proglinazine O 50Promacyl O 50Promecarb O 50Prometon III 37Prometryn III 37Pronamide, see Propyzamide U 44Propachlor II 31Propamocarb U 44Propanil II 31Propaphos O 50Propaquizafop U 44Propargite III 37Propazine U 44Propetamphos Ib 23Propham U 44Propiconazole II 31Propineb U 44Propoxur II 31Propyl isome O 50Propyzamide U 44Prosulfocarb II 31Prothiocarb O 50Prothioconazole U 45Prothiofos II 31Prothoate O 50Protiophos, see Prothiofos II 31Proxan O 50Pydanon O 50Pyracarbolid O 50Pyraclofos II 31Pyrazolynate U 45Pyrazon, see Chloridazon III 34Pyrazophos II 31Pyrazosulfuron U 45Pyrazoxyfen II 31

INDEX. CLASSIFICATION OF ACTIVE PESTICIDE INGREDIENTS, CONTINUED

Ia = Extremely hazardous; Ib = Highly hazardous; II = Moderately hazardous;III = slightly hazardous; U = Unlikely to present acute hazard in normal use;FM = Fumigant, not classified; O = Obsolete as pesticide, not classified.

Common name Class Page Common name Class Page

76

Pyrethrins II 31Pyridaben II 31Pyridaphenthion II 31Pyridate III 37Pyridinitril O 50Pyrifenox III 37Pyrimethanil III 37Pyriminobac U 45Pyriproxyfen U 45Pyrithiobac sodium III 37Pyroquilon II 31Quinacetol sulfate O 50Quinalphos II 31Quinclorac III 37Quinmerac U 45Quinoclamine II 31Quinomethionate, see

Chinomethionat III 34

Quinonamid O 50Quinoxyfen U 45Quintozene U 45Quizalofop II 31Quizalofop-p-tefuryl II 31Red squill (Scilliroside) O 50Reglon, see Diquat II 27Resmethrin III 37Rimsulfuron U 45Ronnel (Fenchlorphos) O 48Rotenone II 31Ryania O 50Ryanocline (Ryania) O 50Sabadilla O 50Salicylanilide O 50Salithion (Dioxabenzophos) O 48SAP, see Bensulide II 24Schradan O 50Scilliroside O 50Secbumeton O 50Sec-butylamine, see

Butylamine II 25

Sesamex O 50Sethoxydim III 37Sevin, see Carbaryl II 25Siduron U 45Silvex (Fenoprop) O 48Simazine U 45Simetryn II 31Sodium arsenite Ib 23Sodium borate, see Borax III 34Sodium chlorate II 31Sodium cyanide Ib 23Sodium fluoride O 50Sodium fluoroacetate Ia 20Sodium hexafluorosilicate O 50Spinetoram U 45Spinosad III 37Spirotetramat III 37Spiroxamine II 32Stirofox, see

Tetrachlorvinphos III 38

Strychnine Ib 23Sulfallate O 50Sulfluramid II 32Sulfometuron U 45Sulfotep Ia 20Sulfur, see Sulphur III 37Sulfoxide O 50Sulfuryl fluoride FM 53Sulphur III 37Sulprofos O 502,4,5-T O 50, 51tau-Fluvalinate III 372,3,6-TBA II 32TCA (acid) II 32TCA (sodium salt) III 37TDE O 50Tebuconazole II 32Tebufenozide U 45Tebufenpyrad II 32

INDEX. CLASSIFICATION OF ACTIVE PESTICIDE INGREDIENTS, CONTINUED

Ia = Extremely hazardous; Ib = Highly hazardous; II = Moderately hazardous;III = slightly hazardous; U = Unlikely to present acute hazard in normal use;FM = Fumigant, not classified; O = Obsolete as pesticide, not classified.

Common name Class Page Common name Class Page

77

Tebupirimfos Ia 20Tebutam U 45Tebuthiuron II 32Tecnazene U 45Tedion, see Tetradifon U 45Teflubenzuron U 45Tefluthrin Ib 23Temephos III 37TEPP O 50Terbacil U 45Terbucarb O 50Terbufos Ia 20Terbumeton II 32Terbuthylazine III 38Terbutryn III 38Tetrachlorvinphos III 38Tetraconazole II 32Tetradifon U 45Tetramethrin U 45Tetrasul O 50Thallium sulfate Ib 23Thiabendazole III 38Thiacloprid II 32Thiazafluron O 50Thiazfluorin, see Thiazafluron O 50Thicyofen O 50Thidiazuron III 38Thifensulfuron-methyl U 45Thifluzamide U 45Thiobencarb II 32Thiocyclam II 32Thiodan, see Endosulfan II 27Thiodicarb II 32Thiofanox Ib 23Thiofos, see Parathion Ia 19, 52Thiometon Ib 23Thionazin O 50Thiophanate O 50Thiophanate-methyl U 45

Thioquinox O 50Thioxamyl, see Oxamyl Ib 22Thiram II 32, 51Timet, see Phorate Ia 20Tiocarbazil U 45TMTD, see Thiram II 32, 51Tolclofos-methyl U 46Tolylfluanid U 46Tolylmethylcarbamate, see

Metolcarb II 30

Toxaphene (Camphechlor) O 47, 512,4,5-TP (Fenoprop) O 48Tralkoxydim II 32Tralomethrin II 32Transfluthrin U 46Triadimefon II 32Triadimenol II 32Tri-allate III 38Triamiphos O 50Triapenthenol O 50Triarimol O 50Triasulfuron U 46Triazamate II 32Triazophos Ib 23Triazotion,

see Azinphos-ethyl Ib 21

Tribenuron U 46Tricamba O 50Trichlamide O 50Trichlorfon II 32Trichloronat O 50Triclopyr II 32Tricyclazole II 32Tridemorph II 32Tridiphane O 50Trietazine III 38Trifenmorph O 50Trifloxystrobin U 46Triflumizole II 32Triflumuron U 46

INDEX. CLASSIFICATION OF ACTIVE PESTICIDE INGREDIENTS, CONTINUED

Ia = Extremely hazardous; Ib = Highly hazardous; II = Moderately hazardous;III = slightly hazardous; U = Unlikely to present acute hazard in normal use;FM = Fumigant, not classified; O = Obsolete as pesticide, not classified.

Common name Class Page Common name Class Page

78

Trifluralin U 46Triflusulfuron-methyl U 46Triforine U 46Trimethacarb O 50Triticonazole III 38Trizazotion, see

Azinphos-ethyl Ib 21

Undecan-2-one III 38Uniconazole II 33Validamycin U 46Vamidothion Ib 23

Vernolate O 50Vinclozolin U 46Warfarin Ib 23XMC II 33Xylylcarb II 33Zeta-cypermethrin Ib 21Zinc phosphide Ib 23Zineb U 46Ziram II 33Zoxamide U 46

INDEX. CLASSIFICATION OF ACTIVE PESTICIDE INGREDIENTS, CONTINUED

Ia = Extremely hazardous; Ib = Highly hazardous; II = Moderately hazardous;III = slightly hazardous; U = Unlikely to present acute hazard in normal use;FM = Fumigant, not classified; O = Obsolete as pesticide, not classified.

Common name Class Page Common name Class Page