Pharmaceutical Dosage Forms

ByS.Bohlooli, PhDSchool of Medicine, Ardabil University of Medical Sciences

Dosage Form/ Drug Delivery System by route of administration

Oral Tablets Capsules Solutions Syrups Elixirs Suspensions Magmas Gels Powders

Sublingual Tablets Troches and

Lozenges

Parenteral Solutions Suspensions

Conjunctival Contact lens inserts Ointments

Dosage Form/ Drug Delivery System by route of administration Epicutaneous /

transdermal Ointments Creams Infusion pumps Pastes Plasters Powders Aerosols Lotions Transdermal patches,

discs, solutions

Intraocular/ intraaural Solutions Suspensions

Intranasal Solutions Sprays Inhalers Ointments

Intrarespiratory Aerosols

Dosage Form/ Drug Delivery System by route of administration

Vaginal Solutions Ointments Emulsion foams Gels Tablets Inserts,

suppositories, sponges

Rectal Solutions Ointments Suppositories

Urethral Solutions suppositories

Solid Dosage Forms

Powders and GranulesCapsules and Tablets

Powders and Granules

Powders Blending Powders Medicated Powders Aerosolized Powders

Granules Effervescent

Capsules

Hard Gelatin Capsules Soft Gelatin Capsules

Hard Gelatin Capsules

Tablets Compressed tablets

(C.T.) Multiple Compressed

tablets (M.C.T.) Sugar-Coated Tablets

(S.C.T.) Film Coated Tablets

(F.C.T) Gelatin Coated Tablets Enteric Coated Tablets

(E.C.T.) Buccal or Sublingual

Tablets

Chewable Tablets Effervescent Tablets Molded Tablets Immediate release

Tablets (I.R.) Instant

Disintegrating /Dissolving Tablets

Extended release Tablets (E.R.)

Vaginal Tablets

Compressed Tablets contains:

Medicinal agent Diluents or filler Binders or adhesives Disintergrants Lubricants Miscellaneous adjuncts

Colorants and flavorants

Compressed tablets

Tablets

Multiple Compressed tablets Sugar-Coated Tablets Film Coated Tablets

Gelatin Coated Tablets Enteric Coated Tablets

Modified-Release Dosage Forms and Drug Delivery Systems

Modified Release Extended Release Delayed Release Repeat action Targeted Release

Terminology of extended release Sustained Release (SR) Sustained Action (SA) Prolonged Action (PA) Controlled Release (CR) Extended Release (ER) Timed Release (TR) Long Acting (LA)

Modified-Release Dosage Forms

Extended Release

Example of oral control release capsule

Nonoral Modified-Release Systems

Ocular Parenteral Systems Vaginal Inserts Subdermal Implants

Ocusert: Pilocarpine Modified Released System

Example of Parenteral extended action products

Example of vaginal extended release products

Example of Subdermal extended release products

Semi-Solid Dosage Forms

OintmentsCreamsGelsPastesPlasters

Transdermal Drug Delivery Systems

Example Of transdermal Drug delivery systems

Pharmaceutical Inserts

SuppositoriesInserts

Liquid Dosage forms

SolutionsDisperse systems

Solutions

Oral Solutions Otic Solutions Ophthalmic Solutions Topical Solutions Spirits

Oral Liquid Dosage Forms

Oral solutions Syrups Elixirs Tinctures

Example of Syrup Antihistamine Syrup

1. Chlorpheniramine maleate 0.4g2. Glycerin 25.0ml3. Syrup base 83.0 ml4. Sorbitol solution 283 ml5. Sodium Bezoate 1.0 g6. Alcohol 60.0 ml7. Color and Flavor q.s.8. Purified water to make 1000.0ml

Theophylline Elixir1. Theophylline 5.3 g2. Citric acid 10.0 g3. Liquid Glucose 44.0 g4. Syrup 132

ml5. Glycerin 50.0 ml6. Sorbitol Solution 324.0 ml7. Alcohol 200.0 ml8. Saccharin Sodium 50 g9. Lemon Oil 0.5 g10. FDC Yellow No. 5 0.1 g11. Purified water to make 1000.0 ml

Example of Elixir

Disperse Systems

Suspensions Emulsions Aerosols

Sterile Dosage Forms and Delivery Systems

ParenteralsBiologicalsOphthalmic solutions and suspensions

Injection Types

Automatic injection

Medi-Jector:Needle Free

Novel and Advanced Dosage Forms, Delivery Systems, and Devices

IontophoresisPhonophoresisIntravenous controllers and infusion pumps, lyposomes

Iontophoresis

Phonophoresis

Intravenous controllers