Pie Chart Showing the Breakdown of Gastro-intestinal Prescribing in General Practice in England (July 2007 - June 2008 )

Chronic Bowel Disorders3%Antispasmodics

5%Acute Diarrhoea 3%

Drugs Affecting Intestinal Secretions

1%

Dyspepsia & GORD 8%

Ulcer-Healing Drugs 55%

Local Preps for Anal & Rectal Disorders

3%

Laxatives 22%

© Copyright NHSBSA 2008

Pie Chart Showing the Breakdown of Gastro-intestinal Spending in General Practice in England (July 2007 - June 2008)

Ulcer-Healing Drugs 50%

Antispasmodics 6%

Acute Diarrhoea 1%

Local Preps for Anal & Rectal Disorders 2%

Laxatives 13%

Dyspepsia & GORD 5%

Drugs Affecting Intestinal Secretions

5%

Chronic Bowel Disorders18%

© Copyright NHSBSA 2008

Trends in Prescribing of Antacids and simeticone in General Practice in England

0

20,000

40,000

60,000

80,000

100,000

120,000

140,000

160,000

180,000

Jun-03

Sep-03

Dec-03

Mar-04

Jun-04

Sep-04

Dec-04

Mar-05

Jun-05

Sep-05

Dec-05

Mar-06

Jun-06

Sep-06

Dec-06

Mar-07

Jun-07

Sep-07

Dec-07

Mar-08

Jun-08

Quarter to

Item

s

Co-magaldrox Antacid preparations containing simeticoneSimeticone Magnesium TrisilicateMagnesium oxide Aluminium HydroxideOthers

© Copyright NHSBSA 2008

Trends in Spending on Antacids and simeticone in General Practice in England

0

50,000

100,000

150,000

200,000

250,000

300,000

350,000

400,000

450,000

500,000

Jun-03

Sep-03

Dec-03

Mar-04

Jun-04

Sep-04

Dec-04

Mar-05

Jun-05

Sep-05

Dec-05

Mar-06

Jun-06

Sep-06

Dec-06

Mar-07

Jun-07

Sep-07

Dec-07

Mar-08

Jun-08

Quarter to

NIC

(£)

Co-magaldrox Antacid preparations containing simeticoneSimeticone Magnesium TrisilicateMagnesium oxide Aluminium HydroxideOthers

© Copyright NHSBSA 2008

Trends in Prescribing of Compound Alginate Preparations in General Practice in England

0

200,000

400,000

600,000

800,000

1,000,000

1,200,000

1,400,000

1,600,000

Jun-03

Sep-03

Dec-03

Mar-04

Jun-04

Sep-04

Dec-04

Mar-05

Jun-05

Sep-05

Dec-05

Mar-06

Jun-06

Sep-06

Dec-06

Mar-07

Jun-07

Sep-07

Dec-07

Mar-08

Jun-08

Quarter to

Item

s

Gaviscon Peptac Gastrocote Others

© Copyright NHSBSA 2008

Trends in Spending on Compound Alginate Preparations in General Practice in England

0

1,000,000

2,000,000

3,000,000

4,000,000

5,000,000

6,000,000

Jun-03

Sep-03

Dec-03

Mar-04

Jun-04

Sep-04

Dec-04

Mar-05

Jun-05

Sep-05

Dec-05

Mar-06

Jun-06

Sep-06

Dec-06

Mar-07

Jun-07

Sep-07

Dec-07

Mar-08

Jun-08

Quarter to

NIC

(£)

Gaviscon Peptac Gastrocote Others

© Copyright NHSBSA 2008

Trends in Prescribing of Ulcer-healing drugs in General Practice in England

0

1,000,000

2,000,000

3,000,000

4,000,000

5,000,000

6,000,000

7,000,000

8,000,000

9,000,000

10,000,000

Jun-03

Sep-03

Dec-03

Mar-04

Jun-04

Sep-04

Dec-04

Mar-05

Jun-05

Sep-05

Dec-05

Mar-06

Jun-06

Sep-06

Dec-06

Mar-07

Jun-07

Sep-07

Dec-07

Mar-08

Jun-08

Quarter to

Item

s

Proton pump inhibitors H2-receptor antagonists Others

© Copyright NHSBSA 2008

Trends in Spending on Ulcer-healing drugs in General Practice in England

0

20,000,000

40,000,000

60,000,000

80,000,000

100,000,000

120,000,000

140,000,000

Jun-03

Sep-03

Dec-03

Mar-04

Jun-04

Sep-04

Dec-04

Mar-05

Jun-05

Sep-05

Dec-05

Mar-06

Jun-06

Sep-06

Dec-06

Mar-07

Jun-07

Sep-07

Dec-07

Mar-08

Jun-08

Quarter to

NIC

(£)

Proton pump inhibitors H2-receptor antagonists Others

© Copyright NHSBSA 2008

Trends in Prescribing of and Spending on Helicobacter pylori tests in General Practice in England

0

1,000

2,000

3,000

4,000

5,000

6,000

Jun-03

Sep-03

Dec-03

Mar-04

Jun-04

Sep-04

Dec-04

Mar-05

Jun-05

Sep-05

Dec-05

Mar-06

Jun-06

Sep-06

Dec-06

Mar-07

Jun-07

Sep-07

Dec-07

Mar-08

Jun-08

Quarter to

Item

s

£0

£20,000

£40,000

£60,000

£80,000

£100,000

£120,000

NIC

(£)

Items NIC (£)

© Copyright NHSBSA 2008

Trends in Prescribing of H2-receptor antagonists in General Practice in England

0

200,000

400,000

600,000

800,000

1,000,000

1,200,000

1,400,000

Jun-03

Sep-03

Dec-03

Mar-04

Jun-04

Sep-04

Dec-04

Mar-05

Jun-05

Sep-05

Dec-05

Mar-06

Jun-06

Sep-06

Dec-06

Mar-07

Jun-07

Sep-07

Dec-07

Mar-08

Jun-08

Quarter to

Item

s

Ranitidine Cimetidine Nizatidine Famotidine

© Copyright NHSBSA 2008

Trends in Spending on H2-receptor antagonists in General Practice in England

0

2,000,000

4,000,000

6,000,000

8,000,000

10,000,000

12,000,000

14,000,000

Jun-03

Sep-03

Dec-03

Mar-04

Jun-04

Sep-04

Dec-04

Mar-05

Jun-05

Sep-05

Dec-05

Mar-06

Jun-06

Sep-06

Dec-06

Mar-07

Jun-07

Sep-07

Dec-07

Mar-08

Jun-08

Quarter to

NIC

(£)

Ranitidine Cimetidine Nizatidine Famotidine

© Copyright NHSBSA 2008

Trends in Prescribing of Proton Pump Inhibitors in General Practice in England

0

1,000,000

2,000,000

3,000,000

4,000,000

5,000,000

6,000,000

7,000,000

8,000,000

9,000,000

Jun-03

Sep-03

Dec-03

Mar-04

Jun-04

Sep-04

Dec-04

Mar-05

Jun-05

Sep-05

Dec-05

Mar-06

Jun-06

Sep-06

Dec-06

Mar-07

Jun-07

Sep-07

Dec-07

Mar-08

Jun-08

Quarter to

Item

s

Lansoprazole Omeprazole Esomeprazole Rabeprazole Pantoprazole

© Copyright NHSBSA 2008

Trends in Spending on Proton Pump Inhibitors in General Practice in England

0

20,000,000

40,000,000

60,000,000

80,000,000

100,000,000

120,000,000

Jun-03

Sep-03

Dec-03

Mar-04

Jun-04

Sep-04

Dec-04

Mar-05

Jun-05

Sep-05

Dec-05

Mar-06

Jun-06

Sep-06

Dec-06

Mar-07

Jun-07

Sep-07

Dec-07

Mar-08

Jun-08

Quarter to

NIC

(£)

Lansoprazole Omeprazole Esomeprazole Rabeprazole Pantoprazole

© Copyright NHSBSA 2008

Trends in Prescribing of Lansoprazole by Strength in General Practice in England

0

200,000

400,000

600,000

800,000

1,000,000

1,200,000

1,400,000

1,600,000

1,800,000

2,000,000

Jun-03

Sep-03

Dec-03

Mar-04

Jun-04

Sep-04

Dec-04

Mar-05

Jun-05

Sep-05

Dec-05

Mar-06

Jun-06

Sep-06

Dec-06

Mar-07

Jun-07

Sep-07

Dec-07

Mar-08

Jun-08

Quarter to

Item

s

30mg cap/tabs 15mg cap/tabs

© Copyright NHSBSA 2008

Trends in Prescribing of Omeprazole by Strength in General Practice in England

0

500,000

1,000,000

1,500,000

2,000,000

2,500,000

3,000,000

3,500,000

Jun-03

Sep-03

Dec-03

Mar-04

Jun-04

Sep-04

Dec-04

Mar-05

Jun-05

Sep-05

Dec-05

Mar-06

Jun-06

Sep-06

Dec-06

Mar-07

Jun-07

Sep-07

Dec-07

Mar-08

Jun-08

Quarter to

Item

s

10mg cap/tabs 20mg cap/tabs 40mg cap/tabs

© Copyright NHSBSA 2008

Trends in Prescribing of Aminosalicylates for Inflammatory Bowel Disease in General Practice in England

0

50,000

100,000

150,000

200,000

250,000

300,000

350,000

400,000

450,000

500,000

Jun-03

Sep-03

Dec-03

Mar-04

Jun-04

Sep-04

Dec-04

Mar-05

Jun-05

Sep-05

Dec-05

Mar-06

Jun-06

Sep-06

Dec-06

Mar-07

Jun-07

Sep-07

Dec-07

Mar-08

Jun-08

Quarter to

Item

s

Mesalazine Sulfasalazine Olsalazine Balsalazide

© Copyright NHSBSA 2008

Trends in Spending on Aminosalicylates for Inflammatory Bowel Disease in General Practice in England

0

5,000,000

10,000,000

15,000,000

20,000,000

25,000,000

Jun-03

Sep-03

Dec-03

Mar-04

Jun-04

Sep-04

Dec-04

Mar-05

Jun-05

Sep-05

Dec-05

Mar-06

Jun-06

Sep-06

Dec-06

Mar-07

Jun-07

Sep-07

Dec-07

Mar-08

Jun-08

Quarter to

NIC

(£)

Mesalazine Sulfasalazine Olsalazine Balsalazide

© Copyright NHSBSA 2008

Trends in Prescribing of Corticosteroids for Inflammatory Bowel Disease in General Practice in England

0

5,000

10,000

15,000

20,000

25,000

30,000

35,000

Jun-03

Sep-03

Dec-03

Mar-04

Jun-04

Sep-04

Dec-04

Mar-05

Jun-05

Sep-05

Dec-05

Mar-06

Jun-06

Sep-06

Dec-06

Mar-07

Jun-07

Sep-07

Dec-07

Mar-08

Jun-08

Quarter to

Item

s

Prednisolone Hydrocortisone Budesonide

© Copyright NHSBSA 2008

Trends in Spending on Corticosteroids for Inflammatory Bowel Disease in General Practice in England

0

100,000

200,000

300,000

400,000

500,000

600,000

700,000

800,000

900,000

Jun-03

Sep-03

Dec-03

Mar-04

Jun-04

Sep-04

Dec-04

Mar-05

Jun-05

Sep-05

Dec-05

Mar-06

Jun-06

Sep-06

Dec-06

Mar-07

Jun-07

Sep-07

Dec-07

Mar-08

Jun-08

Quarter to

NIC

(£)

Prednisolone Hydrocortisone Budesonide

© Copyright NHSBSA 2008

Trends in Prescribing of Laxatives in General Practice in England

0

500,000

1,000,000

1,500,000

2,000,000

2,500,000

3,000,000

3,500,000

4,000,000

Jun-03

Sep-03

Dec-03

Mar-04

Jun-04

Sep-04

Dec-04

Mar-05

Jun-05

Sep-05

Dec-05

Mar-06

Jun-06

Sep-06

Dec-06

Mar-07

Jun-07

Sep-07

Dec-07

Mar-08

Jun-08

Quarter to

Item

s

Osmotic laxatives Stimulant laxatives Bulk-forming laxatives Others

© Copyright NHSBSA 2008

Trends in Spending on Laxatives in General Practice in England

0

2,000,000

4,000,000

6,000,000

8,000,000

10,000,000

12,000,000

14,000,000

16,000,000

Jun-03

Sep-03

Dec-03

Mar-04

Jun-04

Sep-04

Dec-04

Mar-05

Jun-05

Sep-05

Dec-05

Mar-06

Jun-06

Sep-06

Dec-06

Mar-07

Jun-07

Sep-07

Dec-07

Mar-08

Jun-08

Quarter to

NIC

(£)

Osmotic laxatives Stimulant laxatives Bulk-forming laxatives Others

© Copyright NHSBSA 2008

Trends in Prescribing of Lactulose Solution in General Practice in England

0

100,000

200,000

300,000

400,000

500,000

600,000

700,000

Jun-03

Sep-03

Dec-03

Mar-04

Jun-04

Sep-04

Dec-04

Mar-05

Jun-05

Sep-05

Dec-05

Mar-06

Jun-06

Sep-06

Dec-06

Mar-07

Jun-07

Sep-07

Dec-07

Mar-08

Jun-08

Quarter to

Qua

ntity

(Litr

es)

© Copyright NHSBSA 2008

Trends in Prescribing of Aspirin (BNF 2.9 & 4.7.1) in General Practice in England

0

1,000,000

2,000,000

3,000,000

4,000,000

5,000,000

6,000,000

7,000,000

8,000,000

9,000,000

Jun-03

Sep-03

Dec-03

Mar-04

Jun-04

Sep-04

Dec-04

Mar-05

Jun-05

Sep-05

Dec-05

Mar-06

Jun-06

Sep-06

Dec-06

Mar-07

Jun-07

Sep-07

Dec-07

Mar-08

Jun-08

Quarter to

Item

s

Other Aspirin Formulations E/C

© Copyright NHSBSA 2008

Trends in Prescribing of Aspirin (BNF 2.9 & 4.7.1) in General Practice in England

0

1,000,000

2,000,000

3,000,000

4,000,000

5,000,000

6,000,000

7,000,000

8,000,000

9,000,000

Jun-03

Sep-03

Dec-03

Mar-04

Jun-04

Sep-04

Dec-04

Mar-05

Jun-05

Sep-05

Dec-05

Mar-06

Jun-06

Sep-06

Dec-06

Mar-07

Jun-07

Sep-07

Dec-07

Mar-08

Jun-08

Quarter to

Item

s

Aspirin 2.9 Aspirin 4.7.1

© Copyright NHSBSA 2008

Trends in Prescribing of NSAIDs in General Practice in England

0

1,000,000

2,000,000

3,000,000

4,000,000

5,000,000

6,000,000

Jun-03

Sep-03

Dec-03

Mar-04

Jun-04

Sep-04

Dec-04

Mar-05

Jun-05

Sep-05

Dec-05

Mar-06

Jun-06

Sep-06

Dec-06

Mar-07

Jun-07

Sep-07

Dec-07

Mar-08

Jun-08

Quarter to

Item

s

Diclofenac Ibuprofen Naproxen Meloxicam Rofecoxib Celecoxib Etoricoxib Others

© Copyright NHSBSA 2008

Trends in Spending on NSAIDs in General Practice in England

0

10,000,000

20,000,000

30,000,000

40,000,000

50,000,000

60,000,000

70,000,000

Jun-03

Sep-03

Dec-03

Mar-04

Jun-04

Sep-04

Dec-04

Mar-05

Jun-05

Sep-05

Dec-05

Mar-06

Jun-06

Sep-06

Dec-06

Mar-07

Jun-07

Sep-07

Dec-07

Mar-08

Jun-08Quarter to

NIC

(£)

Diclofenac Ibuprofen Naproxen Meloxicam Rofecoxib Celecoxib Etoricoxib Others

© Copyright NHSBSA 2008

Trends in Prescribing of Cyclo-oxygenase-2 Selective Inhibitors in General Practice in England

0

200,000

400,000

600,000

800,000

1,000,000

1,200,000

1,400,000

1,600,000

1,800,000

2,000,000

Jun-03

Sep-03

Dec-03

Mar-04

Jun-04

Sep-04

Dec-04

Mar-05

Jun-05

Sep-05

Dec-05

Mar-06

Jun-06

Sep-06

Dec-06

Mar-07

Jun-07

Sep-07

Dec-07

Mar-08

Jun-08

Quarter to

Item

s

Meloxicam Rofecoxib Celecoxib Etoricoxib Etodolac Others

© Copyright NHSBSA 2008

Trends in Spending on Cyclo-oxygenase-2 Selective Inhibitors in General Practice in England

0

5,000,000

10,000,000

15,000,000

20,000,000

25,000,000

30,000,000

35,000,000

40,000,000

45,000,000

50,000,000

Jun-03

Sep-03

Dec-03

Mar-04

Jun-04

Sep-04

Dec-04

Mar-05

Jun-05

Sep-05

Dec-05

Mar-06

Jun-06

Sep-06

Dec-06

Mar-07

Jun-07

Sep-07

Dec-07

Mar-08

Jun-08

Quarter to

NIC

(£)

Meloxicam Rofecoxib Celecoxib Etoricoxib Etodolac Others

© Copyright NHSBSA 2008