pien tze huang （ 600436 ） —— national treasure ,miraculous drug

1

PIEN TZE HUANG （ 600436 ）—— National Treasure ,Miraculous Drug

Carrying five hundred years' brilliance,

Refounding new century's splendidness.漳州片仔癀药业股份有限公司

ZHANGZHOU PIENTZEHUANG PHARMACEUTICAL CO.,LTD.

2

—Brief Introduction

Zhangzhou PIEN TZE HUANG PHARMACEUTICAL CO.,LTD. is a national large second class enterprise, one of the 520 national key enterprises. It has been selected into the best beneficial one of the national 500 enterprises. The company has developed into a new high-technology enterprise with a postdoctoral research station. In 2001 the company was chosen as a "Value contrast, keep promise" unit. In 2004 all the dosage forms achieved GMP attestation. The company became one appearing on the stock market with 180 indexes of stock exchange securities in 2005 In 2006, 《 In Ministry of Commerce's notice concerning affirming the first lot of "China Time-honored Brand" 》 PIEN TZE HUANG was selected smoothly.

3


In 2006, the company was chosen as the first affirmation of "China Time-honored Brand" and was selected into one ranking twentieth on the list of one hundred companies with great strength for their famous brand value of China Time-honored Brand. The company is the only one which has entered in the list of one hundred China Time-honored Brands with great strength.

4

The industrial property right such as formula, technology, brand exclusively belongs to the company. The company possesses the products and technology which have been passed on from generation to generation, with a long history. They are of bright and traditional Chinese cultural background and profound cultural inside information. And they have won widespread popularity in society, and formed a good brand with high reputation.


1.Jia Jing(emperor) imperial hospital of Ming Dynasty in 1555 2.Pushanyan Temple 3.Tong Shan Tang United Pharmaceutical Factory in 1956 4.Zhangzhou City Pharmaceutical Factory 5.Zhangzhou PIEN TZE HUANG GROUP(Zhangzhou City Pharmaceutical Factory) 6.Zhangzhou PIEN TZE HUANG GROUP,Zhangzhou PIEN TZE HUANG PHARMACEUTICAL CO.,LTD 7.In June 2003, the company went on the stock market in Shanghai's stock exchange.

5

Brand and Quality

1 、 BrandPIEN TZE HUANG continues to hold national quality gold medal prize, China famous trade mark, first-class protected kind of Chinese medicines, a protected kind of national origin mark, and China Time-honored Brand.

2 、 Quality

The selection of raw materials must be genuine. The formula must be true essence. The production must be consummate.

Features of products: high content in effective element, exact efficiency, quick drug action

6

Medicines of PIEN TZE HUANG brand, series of cosmetics, series of daily and chemical articles, and health products.

----Nearly 40 kinds of medicines are produced and sold: PIEN TZE HUANG and its capsule, compound PIEN TZE HUANG

ointment, yin dan ping gan capsule(patented drug),xin shu bao tablet, qing re zhi ke granule(patented drug), chuan bei qing fei syrup, huo xiang zheng qi shui and its capsule, jin mu gan mao tablet(patented drug), zen ru gao(patented drug), ling qiao jie du pian, shao lin bone setting essence, liu wei di huang wan, bezoare detoxicating tablets, xiao chai hu chong ji, royal jelly capsule, chin pai di huang wan, qi ju di huang wan,xiao sha liu jun wan, xiao yao wan, compoind pien tze huang tablet, compound dan shen tablet, hu gan pian, pien tze huang hemorrohoidal ointment.

The products to be prepared are jin tang ning(a national new drug), liu wei di huang concentrated tablet, beeglue capsule, jin kui sheng qi wan, ketoconazole ointment and a series of health food.

7

The company has solely produced the Chinese patent drug —— PIEN TZE HUANG which is a rare and traditional drug and has a long history of 450 years. Its exclusive miraculous curative effect has earned high praise from the public and it has got the good reputation, "national treasure, miraculous drug", "China specific antibiotic " in the Chinese medical world at home and abroad

——PIEN TZE HUANG national treasure, miraculous drug

1. A Chinese patent drug with the strongest legendary flavor and cultural inside information

2. A Chinese patent drug with the best influence the world over.

3.A wide-spread Chinese patent drug in use.

8

1 、 A long history , palace secret recipe Early in Chinese medical treasure there was a good reputation for

"Tong Ren Tang in the north" and "PIEN TZE HUANG is the south". There was a longer history of PIEN TZE HUANG with the same reputation as Tong Ren Tang.

In 1555, in Emperor Wan Li period of Ming Dynasty(Yunnan's baiyao, a white medical powder for treating haemorrage, wounds,etc , came into being in 1902;Tong Ren Tang was founded in the eighth year of Emperor Kang Xi in Qing Dynasty, 335 years from now; An Gong Niu Huang Wan has a long history of 200 years; Liu Wei Di Huang Wan of 250 years), a palace doctor of Ming Shi Zong(an emperor) took the secret recipe of Pien tze huang with him and escaped from the capital because of his being discontented with the tyranny. After passing through many different places, he lived in seclusion in Zhangzhou Fujian and became a monk. Later on for the sake of helping the endangered and relieving the less privileged, he refined Pien Tze Huang with the palace top secret recipe by using unique technology.

═ A Chinese patent drug with the strongest legendary flavor and cultural inside information

9

2 、 Legendary story（ 1 ） Acute hepatitis A in Shanghai ： In 1988, acute hepatitis A in shanghai and neighboring provinces broke out. Owing to its quick curative effect and high cure rate, Pien Tze Huang drugs were all sold out in a short time and so Pien Tze Huang, the wonder, rose to fame at that time!

（ 2 ） State gift ： In 1972, when China established diplomatic relations with Japan, Pien Tze Huang was given as state gift for Japanese Prime Minister Tanaka. Thus the Japanese people poured into or entrusted others to buy Pien Tze Huang in Hong Kong. At that time, there appeared sensational occasion lining up for purchase in quota.

（ 3 ） Legend in Vietnamese War ： Pien Tze Huang was found at first to have wonderful effect on a knife and bullet wounds and a bee sting or a snake bite. It is said that in 1960, during the Vietnamese War the U.S. army purchased a lot of Pien Tze Huang as military supplies for the soldiers fighting in the jungle. That was surprising to the west. From then on Pien Tze Huang rose its fame considerably in the western countries.


10

（ 4 ） Public praise in a great vogue In the areas of Hong Kong, Macao, Southeast Asia, Japan, and South Korea, Pien Tze Huang has enjoyed high notability and a good reputation through the effect of its public praise. Many old overseas Chinese regard Pien Tze Huang as a "miraculous drug". When approaching their end, the dying must take Pien Tze Huang, or they will die with everlasting regret. If they are not satisfied with their wish, they will blame their children for their unworthiness. Because it was rare and limited supply, Pien Tze Huang had been supplied with a written slip of paper before 1996. For non-resident people only 20 grains were permitted to be taken with them when leaving the country. And thus in the TV play "Shanghailanders in Tokyo", a Chinese student (The actor Ge You plays the student) who studies in Tokyo resells Pien Tze Huang at a profit. The Japanese especially adore Pien Tze Huang.


11

4 、 Gold Prize of Quality In 1979, Pien Tze Huang won national silver prize ； In 1984 and 1989,it won national gold prize successively ； In 1994, it was classified as the national first-class protected kind of Chinese

medicines, one of a few kinds in the earliest time ； In 1995, State Traditional Chinese Medicinal Administration awarded a

certificate of Famous Products of China's Traditional Chinese medicines 。

3 、 Protection with top secret The recipe and technology of Pien Tze Huang are under national top secret. In 1965, it was classified as a key

protected Chinese medicinal preparation with national top secret by the State Traditional Chinese Medicinal Administration and the State Secret Bureau.In 2002 series of Pien Tze Huang drugs were set as a product of national origin mark by the State General Administration Quality Monitoring and Inspection and Quarantine of Commodities. If the protection system of traditional Chinese medicine is abolished, Pien Tze Huang will become rarer because of its top secret.

In June,2005 Ministry of Public Health, State Pharmaceutical Administration, Ministry of Forestry, State Administration for Industry and Commerce, formed an expert group to select repeatedly from more than 280 kinds of Chinese patent drugs containing musk in the country, finally only Pien Tze Huang and three other drugs were permitted to use natural musk. No other Chinese patent drugs were permitted to use natural musk. And thus Pien Tze Huang has become the special kind of drug which obtains state administrative protection.


12

5 、 Sole management

Pien Tze Huang is a palace secret recipe handed down from Ming Dynasty. Among the present rare Chinese Patent drugs, only Zhangzhou Pien Tze Huang, the one single product can be produced exclusively not only in China but also in the world. That is of strong competence and no substitute for it. It is one of the four kinds of drugs in five enterprises which are permitted to use musk as raw material.

6 、 Sole exception in law(China famous trade mark)

According to "Medicine Law" and "Trade Mark Law" in the country, the name of medicine should not be registered as a trademark name. Pien Tze Huang is the name of product. In 1989, the Bureau of Trademark of State Administration for Industry and Commerce specially approved Pien Tze Huang registered as the name of trademark. That is one unique case in the country — Pien Tze Huang of Pien Tze Huang brand, the name of drug has the same trademark as the name of the drug itself. In 1998,"PIEN TZE HUANG" was chosen as famous trademark in Fujian Province; in 1999,"PIEN TZE HUANG" was chosen as famous trademark in China, which has gained the protection of "International Trade Mark Madrid Agreement".


13

7 、 Great concern shown by the Party and State.

These years, a dozen

of the Party and State leaders(including Yang Shangkun, Jia Qinglin, Wang Zhaoguo and others) arrived to visit and give valuable guidance to the enterprise.


14


The following are inscriptions from the important figures for highly praising Pien Tze Huang.

15

1 、 A long history of export to quite a lot of foreign countries As a good drug for keeping fit, people from south Fujian braved the journey to southeast Asia, Pien

Tze Huang accompanying with them throughout history. And therefore, The areas of southeast Asia have become the main markets for Pien Tze Huang.

The overseas sales of Pien Tze Huang have made up about half of the total sales in the company, and exported to these countries and areas such as Hong Kong, Macao, Taiwan, Singapore, Japan, the Republic of Korea, the Philippines, Malaysia, the Kingdom of Thailand, the Socialist Republic of Viet Nam, the Republic of Indonesia, the Commonwealth of Australia, Canada, the U.S., the Republic of Argentina, and the Federative Republic of Brazil.

≡A Chinese patent drug with the strongest international influence

16

2 、 The champion in earning foreign exchange through export.

Since 1988, the value of earning foreign exchange through export of Pien Tze Huang has been over US$10.000.000. For many years in succession Pien Tze Huang has gained the champion in the country with a single Chinese patent drug in earning foreign exchange through export. In recent years, the situation in export of Pien Tze Huang is as follows ：


Year Total value of Chinese patent drug

Pien Tze Huang

Percentage of Pien Tze Huang

2000 9991 889 8.90%2001 11219 1039 9.30%

2002 11786 1249 10.60%

2003 11200 1211 10.80%

2004 13900 1373 9.90%

2005 15300 1404 9.18%

2006 13500 1452 10.76%

17

3 、 The greatest popularity and best reputation outside the boundary of the country （ 1 ） Chinese community ： A 、 Once a Chinese reporter working in Brazil had sudden attack of hepatic disease with

transaminase 1600U, high fever, ascites, hemetochezia and difficult intake. After the consultation of famous experts in hepatopathy, the condition remained unchanged. The reporter's life was in danger. Just when people extremely worried about that, an old overseas Chinese Zhou Yunjian, honorary chairman of the Hakkas' Chongzheng Society, came to offer a box of "Pien Tze Huang". After getting the agreement of the hospital and having taken the drug for 13 days, all the indexes of blood tests basically returned to normal. From then on, Pien Tze Huang is called "the drug bringing the dying back to life" (excerpts from "ALL-China Sanitary Industry" No.6,1999)

B 、 Early in the 1950's, the famous old practitioner of Chinese medicine, Sheng Guorong reported for the first time in "Journal of Chinese Medicine" on the clinical curative effect with Pien Tze Huang in the treatment of cancers. At that time an old overseas Chinese, who had resided in the Philippines for over 40 years, suffered from hepatocarcinoma. He spent quite a lot of money sending for western medical doctors for curing his illness. They, however, affirmed, "At most he can live three mouths more only". The sick old overseas Chinese held out a hope of recovery and returned to China to consult Professor Sheng Guorong. The profess treated him by using Pien Tze Huang with houttuynia. After half a year's treatment, all indexes of liver function returned to normal. Thus, Pien Tze Huang caused a sensation throughout the Philippines and its great fame spread far and wide.


18


（ 2 ） In non-Chinese community: Such as Japanese Friendship Society of Pien Tze Huang, also the famous Japanese, doctor of medicine, Yamanaka, wrote a book specially dealing with the miraculous effect of Pien Tze Huang in the treatment of hepatic disease, and he used a sophisticated instrument to analyze Pien Tze Huang. Test shows that although the component and content of Pien Tze Huang can be in part analyzed out, the producing technology still remains unknown. The top secret, dispensing and unique technology remain mysterious.

Note of the picture:Recovery capability verified by a long history of 3000 years in China.Chinese recipe of radix notoginseng, Pien Tze Huang.Defeat hepatic disease.Doctor of medicine, Yamanaka.Secret opens to the public!A Chinese medicine with a dramatic effect on hepatic disease.Excellent effect on such hepatic diseases as hepatic disturbance, acute or chronic hepatitis, fatty liver, fulminant hepatitis, alcoholic hepatic disturbance, hepatic insufficiency.

19

1. Implication of "Pien Tze Huang"

In the dialect of south Fujian, Pien Tze Huang means "different inflammations can be cured with a single tablet". Because of its miraculous curative effect, it is very popular among the people and becomes a treasure of driving out evils among the folks in Zhangzhou. It is customary for the people in Zhangzhou to give Pien Tze Huang as a present when they pay a visit to their relatives, implying that if any illness, Pien Tze Huang can get rid of it, if not, it can keep you in good health.

A Chinese patent drug used in the most wide-spread range

Its functions stretches over therapy, hygiene, cosmetology, etc.

and may be related as a marvel of medical science.

2. Definition of the drug directions Indications: Acute and chronic hepatitis, otitis, ophthalmitis, gingival pyogenesis,

laryngeal swelling pain, tonsillitis, aphtha, tongue abscess, sprain, burn, cut, bullet wound, bruise, sprain, bee sting, snake-bite, carbuncle, furuncle, and all infections and pain and fever caused by inflammations.

20

3. Hereditary secret formula is deciphered. The main ingredients of Pien Tze Huang, the "miraculous drug" which has been open

to the public are four rare Chinese medicines: musk, Calculus Bovis, snake gallbladder, pseudo-ginseng. The miraculous effect, however, is beyond the effect of the simple integration of the above four medicines. The specific dispensing and exclusive technology still remain unknown.


Its functions stretches over therapy, hygiene, cosmetology, etc.

and may be related as a marvel of medical science.

21

4. A discovery of modern science and technology

(1)Project of Hong Kong Chinese University Pien Tze Huang is a research project which is the

sole one gained the subsidization of Innovation and Technology Fund from Hong Kong government. Hong Kong Chinese University carries out the study on the protection of the liver.

The person in charge of the research project is Yao Dawei, academician, the Loyal Biology Academy. The study shows that Pien Tze Huang can reduce enzyme obviously , and ease the damage caused by alcohol and poisonous substance, and with the method of molecular biology, the study verifies that Pien Tze Huang can enhance liver cell regeneration. The result was published in the world's famous Danish journals, 《 Pharmacology & Toxicology 》 , 《 Human & Experimental Toxicology 》


22


(2) National 863 Anticancer program Improvement of cancer symptom and inhibition of pain. Clinical study of the anti cancer treatment with Pien Tze Huang capsules was chosen as National "863 program" in 2004. Clinical study reveals that Pien Tze Huang is significantly superior to control group. In reducing tumor body, remitting pain of patients, and improving the survival quality of patients, the total effective rate is 85.3%, significantly higher than control group 59%. In alleviating chemotherapeutic toxic action and side-effects and in the patients taking Pien Tze Huang, nausea, vomiting, anorexia, dullness, bitter taste in the mouth, laryngoxerosis, and diarrhea caused by chemotherapeutic drugs, the improvement of hemogram and liver function index are all superior to the control group.

Note of picture:Clinical study of the anti cancer treatment with Pien Tze Huang.National 863 program.

23

5. The effects of Pien Tze Huang may be summed up as follows:

(1)Eliminating pathogenic factor and supporting health energy. Enhancing immunity, protecting health.

(2)Possessing specific therapeutic

effect on different tumors and toxin, innominatal hyperthermia and innominatal hypothermia


24

(4)Improvement of cancer symptom and inhibition of suffering

Pien Tze Huang has a significant curative effect in the treatment of tumors, especially in hepatocarcinoma, carcinoma of stomach, intestinal cancer,etc. Clinical study of anti-cancer therapy with Pien Tze Huang capsules was chosen as national "863 program" in 2004.


(3)Specific effect in the treatment of different types of hepatitis

There is a significant and fast curative effect on different types of hepatitis, of which the total effective rate in the acute stage of virus hepatitis and active stage of chronic hepatitis is 82%. Years' practice has proved the miraculous effect of "anti-inflammation with a single tablet only" on the pain and fever caused by different inflammations in hepatitis,etc., and to which many other Chinese patent medicines can not be comparable.

25

(5)Preoperative and postoperative uses, anti-inflammation, analgesia, anti-infection of cut wound, acceleration of wound heal. Pien Tze Huang is used in surgery by 50% in Indonesian markets.


(6)Significant function in prevention and hygiene—improvement of immunity, anti-senility, protection of the liver, prevention of drunkenness, removing fire and reducing toxicity.

26


(7)A certain effect on cosmetology Legend of Pien Tze Huang pearl cream of Huang Hou Brand (a gift for Belgian Empress, a

surprise to Mrs. Lao An, Prime Minister Zhu's wife)

Japanese giant film star Nonuko Otowa (playing "Axin") and her daughter used the product, and then they conveyed their profuse praise, through Ministry of Culture, "Among the products we have ever used, Pien Tze Huang pearl cream counts as the best one. It is superior to any kind of pearl creams.

In 1994 Comrade Zhu Rongji's wife, Madam Lao An came to the company to make an investigation in the series of cosmetics of "Huang Hou Brand" which is praised highly by foreign friends

27

Social Big Clinic

Pien Tze Huang has a significant improvement in treating heat hematoma and dengue fever in Indonesia, prostatitis in Japan, protection and treatment of venereal disease in Thailand, and in Sichuan Province, Pien Tze Huang was found to show an obvious effect on drug addicts and yaotou wan (a narcotic) addicts. The most magical point of Pien Tze Huang lies in the fact that it has always worked miracles. The limits of Pien Tze Huang usage have been expanded continually in practical use. Many efficacies are continually discovered. It can also treat lots of difficult diseases by means of "Different diseases are treated with the same therapy". It is praised as "Chinese miraculous drug", "the common foe of diseases".

28

Carrying five hundred years' brilliance,

Refounding new century's splendidness

From above major characteristics we can further to sum up seven specific features: Mystery: Origin in the palace secret formula in Ming Dynasty in 1555. Uniqueness ： Sole production in the world. The name of medicine, business establishment and stock are three in one for short. Exclusiveness ： Products with State top secret . The company belongs to the key unit which keeps in contact with Bureau of State Security and Bureau of State Secrecy. Authoritativeness: National first-class protected kind of Chinese medicines, product with state gold medal prize, state famous trademark, product with famous brand, a protected kind of state origin mark. Pien

Tze Huang is one of the only three national top secret products(Yunnan's Baiyao, quick-acting

heart reliever). International character ： Pien Tze Huang is exported to these countries and areas such as Hong Kong, Macao, Taiwan, South Korea, Japan, the U.S., southeast Asia. For many years in succession, it has gained the champion in the country with a single Chinese patent drug in earning foreign exchange through export. Extensiveness: Pien Tze Huang has extensive effects(multiple effects as therapy, health care, beauty), extensive derivatives and has gained wide-ranging concern from the leaders of the Party and the nation. Lastingness ： A long history of 450 years, the longer, the more thriving!

29

Carrying five hundred years' brilliance,Refounding new

century's splendidness.

Thanks!

漳州片仔癀药业股份有限公司ZHANGZHOU

PIENTZEHUANG PHARMACEUTICAL

CO.,LTD

• 1: 国宝神药 : National treasure, magical drug• 2: 百病可去 : Getting rid of all diseases• 3: 国药奇葩 : A marvel of national medicine.• 4: 国宝良药 , 普济众生 : National treasure, good medicine. Benefit mankind, relieve people in need.• 5: 增创优势 , 再造辉煌 : Further to bring forth new superiority, create more

brilliant result.• 6: 创一流业绩 , 振国企雄风 : Pioneer first-class achievement, inspire the vigor of state enterprise.

30

附 : 第 14 页 , 名人题词的英译

pien tze huang （ 600436 ） —— national treasure ,miraculous drug

Documents