placenta and fetal membranes 2010 1
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PLACENTA AND THEFETAL MEMBRANES
(chorion,amnion, yolk sac, allantois)
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First !!k o" #!$!lo%m!nt
Oocyte(fertilization)zygote4-cell stage (2 days)morula(ball)blastocysteinner cell mass (embryo)
outer cell mass(trophoblast)
(extraembronic membranes)
From
oocyte to
blastocyst
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#&O30 "##$
#piblast and hypoblast
mnion and yol5 sac
!rophoblast%
yncytiotrophoblast% 6acunae appear in thesyncytiotrophoblast maternal blood flo1s into the
lacunae77uteroplacental circulation+2 day77ad8acent lacunae ad8acent lacunae ha'e fused to
form lacunar net1or5s gi'ing a sponge li5e appearance to the
!rophoblast
#ndometrium%aternal endometrial capillaries ha'e dilatedand become congested to form sinusoids
9rimary chorionic 'illi% cellular extensions of the cytotrophoblas in tothe syncytiotrophoblast
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!/IR0 "##$
!RI6I3R :#R 0I&
9RII!I;# !R#$* 3O!O&/OR0 30 3#
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Plac!nta
fetomaternal organ for nutrient and gas
exchange
Fetal portion% de'elops from the chorionic sacaternal portion% de'elops from the
endometrium7decidua
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F&NCT'NS
9rotection
3utrition
Respiration#xcretion
/ormone production
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DEC'D&A
!hree regions 0ecidua basalis% deep to conceptus 0ecidua capsularis% o'erlying the conceptus
0ecidua parietalis% the remainings the coneeptus enlarges the dicidua capsularis
bulges ingt he uteine ca'ity and e'entually contactsthe decidua paritalis* obliterating the uterine ca'ityand by 22-24 1ee5s it degenerates due to reduced
blood supply !he smooth chorion fuses 1ith the decidua
capsularis
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mooth chorion> in the eighth 1ee5 the 'illi in
the decidua capsularis become compressed
reducing blood supply to them producing a
relati'ely a 'ascular area the smooth chorion
or chorion la'ae
,ushy chorion%!he 'essels associated 1ith
the basalis branch profusely and enlargeforming bushy chorion or chorion frondosum
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9lacenta de'elops from the decidua basalis and the chorionfrondusom
It is usually discoid in shape
s the chorion in'ades the decidua se'eral 1edge shaped areasare formed in the decidua the placental septa theat pro8ectto1ard the chorionic plate !hese septa di'ide the fetal part ofthe placenta into irregular con'ex area called cotyledons
!he iner'illous space is di'ided by the into compartments by theplacental septa aternal blood enters the spaces through spiral
arteries and is drained into endometrial 'eins !he placental membrane% until 2? 1ee5s it consists of
syncytiotrophoblast* cytotrophoblast* connecti'e tissue of 'illi*endothelium of fetal capillaries
fter 2?th1ee5 cytotrophablast o'e rthe branch 'illi is attenuatedlea'ing patches of syncytiotrophoblast 3o1 th placental
membrane consists of three layers In some areas the placentalmembrane becomes extremely thin* at hese sites thesyncytiotrophoblast comes in direct contact 1ith the fetalcapillary endothelium
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@Implantation 1ith inner cell mass to1ards uterine 1all@!rophoblast
@&ytotrophoblast777cells around the inner cell mass@yncytiotrophoblast7syncytium of cells that becomes placenta
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Plac!nta "ormation
6acunae form 1ithin synctiotrophoblast--maternal blood fillsthese spaces
;ili form 1ith embryonic capillaries do1n middle
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Plac!nta "ormation
;illi bathed in maternal blood in lacunae--exchange of nutrients* O2*&O2
fter + 1ee5s* full placenta--panca5e-shaped organ
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th!r !tra!m*ryonic tiss+!s &ellular trophoblast forms
amnion* yol5 sac Fetal cells shed into amniotic
ca'ity 1hich fills 1ith fluidfrom fetal 5idneys extretedthrough ureter* bladder*urethra
mniocentesis--sample ofamniotic fluid ta5en 1ithhypodermic needle
9art of yol5 sac Asuc5edB intoembryo to form endermicbladder
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Em*ryo %ro%!r
I& forms hypoblast (yello1--becomes endoderm) and epitblast(blue--becomes ectoderm)
ee handout for all adultderi'ati'es of embryonic tissues--/O" FR "#C;# &O#DD
Animated movie of fetal deveopment
http://www.cvillepregnancy.org/fetal.html
http://www.cvillepregnancy.org/fetal.htmlhttp://www.cvillepregnancy.org/fetal.htmlhttp://www.cvillepregnancy.org/fetal.htmlhttp://www.cvillepregnancy.org/fetal.html -
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Fig. 24.27
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