post 08 - energy's complement — glutathione

8/12/2019 Post 08 - Energy's Complement Glutathione

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This document can be freely shared if no changes are made to it. 1 | P a g e

In my research regarding the optimizing of health,

I had correctly concluded that energy was absolutely

necessary, both for life itself and the maintenance of it.However, I had failed to consider the removal of toxins

and free radicals that daily invade our bodies, which

shorten and compromise our lifespans. Similar to driving

with a foot on the gas and brake at the same time, energy

alone cannot optimize health if there are toxins present

that diminish its positive effect.

The process responsible for the removal of toxins and free radicals is the Immune

System. These toxins include not only drugs but also pathogens and foreign antigens suchas viruses, bacteria, parasites, fungi and even pre-cancerous cells, all of which cause

cellular damage, toxicity and disease. Free radicals are the result of the normal and

necessary result of oxidation used to acquire energy, but left unchecked, they can cause

chain reactions leading to catastrophic

consequences. Donating one of their many

electrons to neutralize free radicals will in

turn oxidize the anti-oxidants, where

reducing with NADPH as an electron donor

will restore them. However, neutralizing free

radicals in this fashion prevents them from

stealing electrons from healthy cells andwreaking havoc.

Anti-oxidants, such as vitamins C and E, as found in the diet, are helpful in

neutralizing free radicals, but they are not native to your body and cant replenish

themselves when exhausted. Given the immense importance of anti-oxidation in hundreds

of different disease processes, it would be a foregone conclusion to reach that your body

must have an independent built-in mechanism for performing anti-oxidant functions.
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That built-in mechanism is the synthesis of Glutathione (GSH) (pronounced

gloota-thigh-own) from the amino acids L-cysteine, L-glutamic acid, and glycine, and is

the most important molecule you need to stay healthy and prevent disease yet youve

probably never heard of it. (I know that I never did until recently.) Its the secret to

preventing aging, cancer, heart disease, dementia and scores of other ailments anddiseases. While there has been thousands upon thousands of medical articles researched

and written regarding glutathione, the majority of doctors ignore this vast evidence of the

epidemic deficiency of this critical life-giving molecule in favor of selling toxic drugs and

receiving kickbacks from the corporations in which they hold stock. Not only can

glutathione prevent all these diseases, but it can also enable the body to cure them as well

naturally without the numbing expense and crippling side effects of toxic drugs,

radiation, and debilitating surgery.

All drugs have toxic side effects, but some exhibit toxicity at low doses. 1

The key to glutathiones power is the

sulfur (HS) chemical group it contains. Sulfur

can react as either an oxidant or a reducing

agent because of its unique ability to either

donate or receive electrons from other atoms.

Glutathione is the most dominant native anti-oxidant in the body. While all cells in

the body are capable of synthesizing glutathione, most of it is produced and concentrated

in the liverthe bodys major detoxifying organ. This small protein, often labeled the

Master Anti-Oxidant, is crucial for the proper functioning of all the other anti-oxidants

and immune function, controlling inflammation, and maintaining energy.

Glutathione (GSH) has been described for a long time just as a defensive reagent

against the action of toxic xenobiotics (drugs, pollutants, carcinogens). As a prototype

antioxidant, it has been involved in cell protection from the noxious effect of excess

oxidant stress, both directly and as a cofactor of glutathione peroxidases. The

significance of GSH as a major factor in regulation of cell life, proliferation, and death,

should be regarded as the integrated result of all these roles it can play.2

1 NIOSH List of Antineoplastic and Other Hazardous Drugs in Healthcare Settings 2012,page 2, footnote

2 Biochemical Pharmacology, 2003 Oct 15; 66(8):1499-503. The Changing Faces of Glutathione, a Cellular Protagonist. (Abstract)
http://tiny.cc/HowToBeHealthyAtAnyAgehttp://www.cdc.gov/niosh/docs/2012-150/pdfs/2012-150.pdfhttp://www.cdc.gov/niosh/docs/2012-150/pdfs/2012-150.pdfhttp://www.cdc.gov/niosh/docs/2012-150/pdfs/2012-150.pdfhttp://tiny.cc/HowToBeHealthyAtAnyAge


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Toxins from poor

diet, pollution, chemicals,

drugs, stress, trauma, aging,

infections and radiation all

deplete your glutathione. Anormal level of reduced

glutathione to oxidized

glutathione is a 9:1 ratio

because of the bodys

constant purging of toxins

and free radicals. However,

when reduced glutathione levels drop lower than that, your body becomes vulnerable to

cell disintegration from oxidative stress, free radicals, infections and cancer, which

overloads and damages the liver. When a damaged liver fails to detoxify, it results in a

downward spiral of ever-increasing damage to the body, particularly to the genes

responsible for rebuilding the body.


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Nearly all very ill patients are deficient in glutathione. These include people with

chronic fatigue syndrome, heart disease, cancer, chronic infections, autoimmune disease,

diabetes, autism, Alzheimers, Parkinsons, arthritis, asthma, kidney problems, liver disease,

HIV/AIDS, sepsis, trauma, burns and many more. What these people are missing is the

GSTM1 function one of the most important genes needed in the process of creating and

recycling glutathione in the body. If toxins damage this critical GSTM1 gene, the synthesis

of glutathione will be gravely impaired, resulting in a descent into disease and death.

Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct

supergene families. At present, eight distinct classes of the soluble cytoplasmic mammalian

glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and

zeta. This gene encodes a cytoplasmic glutathione S-transferase that belongs to the mu class. The

mu class of enzymes functions in the detoxification of electrophilic compounds, including

carcinogens, therapeutic drugs, environmental toxins and products of oxidative stress, by

conjugation with glutathione. The genes encoding the mu class of enzymes are organized in a

gene cluster on chromosome 1p13.3 and are known to be highly polymorphic. These genetic

variations can change an individual's susceptibility to carcinogens and toxins as well as affect the

toxicity and efficacy of certain drugs. Null mutations of this class mu gene have been linked with

an increase in a number of cancers, likely due to an increased susceptibility to environmental

toxins and carcinogens. Multiple protein isoforms are encoded by transcript variants of this

gene.3

Glutathione has many functions, which all benefit each cell in your body and affects

its life, reproduction, and death.

o It maintains other antioxidants such as vitamins C and E in their active forms.

o It neutralizes free radicals and reactive oxygen compounds.

o It regulates the nitric oxide cycle, which is critical for life.

o

It decreases muscle damage and reduces recovery time.o It plays a fundamental role in protein and prostaglandin synthesis.

o It has a vital function in iron metabolism.

o It plays a fundamental role in DNA synthesis and repair.

o It increases strength and endurance.

3 GSTM1 glutathione S-transferase mu 1 [ Homo sapiens (human) ] Gene ID: 2944, updated on 8-Jun-2014
http://tiny.cc/HowToBeHealthyAtAnyAgehttp://www.ncbi.nlm.nih.gov/gene?Db=gene&Cmd=ShowDetailView&TermToSearch=2944http://www.ncbi.nlm.nih.gov/gene?Db=gene&Cmd=ShowDetailView&TermToSearch=2944http://www.ncbi.nlm.nih.gov/gene?Db=gene&Cmd=ShowDetailView&TermToSearch=2944http://tiny.cc/HowToBeHealthyAtAnyAge


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o It removes toxins from the body.

o It recycles antioxidants.

o It plays a fundamental role in amino acid transport.

o It controls inflammation.

o It plays a fundamental role in enzyme activation.o It shifts metabolism from fat production to muscle development.

o The immune, nervous, and the gastrointestinal systems and lungs especially

depend on the glutathione system.


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There are a number of ways in which you can enhance your health by raising your

glutathione levels. Some of them are simple whereas others will require a more proactive

approach. One particular item of special interest is Immunocal which is listed in thePhysicians Desk Reference,and is qualified for Medicare/Medicaid coverage as well, the last I

knew.

See what a few good doctors and patients say about Immunocal.
http://tiny.cc/HowToBeHealthyAtAnyAgehttp://tiny.cc/Immunocalhttp://tiny.cc/Immunocalhttp://www.pdr.net/full-prescribing-information/immunocal?druglabelid=257http://www.pdr.net/full-prescribing-information/immunocal?druglabelid=257http://www.pdr.net/full-prescribing-information/immunocal?druglabelid=257http://tiny.cc/Immunocalhttp://tiny.cc/HowToBeHealthyAtAnyAge

post 08 - energy's complement — glutathione

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