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D - Programme Specification (Master’s Level) Page 1 of 21 Postgraduate Certificate, Postgraduate Diploma / MSc in Genomic Medicine This document provides a definitive record of the main features of the programme and the learning outcomes that a typical student may reasonably be expected to achieve and demonstrate if s/he takes full advantage of the learning opportunities provided. This programme specification is primarily intended as a reference point for academic and support staff involved in delivering the programme and enabling student development and achievement, for its assessment by internal and external examiners, and in subsequent monitoring and review. Programme Information Award Postgraduate Certificate / Postgraduate Diploma / MSc Programme Title Genomic Medicine Programme code A3GM A3GM24 A3GM2M A3GC4 A3GC12 A3GC1M A3GC4M A3GD8 A3GD24 Awarding Institution Imperial College London Teaching Institution Imperial College London Faculty Faculty of Medicine Department National Heart and Lung Institute (NHLI) Mode and Period of Study This is a modular, flexible programme. For MSc: 1 year full-time (12 months) 2 years part-time (24 months) For PG Diploma (PG Dip): 8 months full-time 2 years part-time (minimum 9-maximum 24 months continuous enrolment) For PG Certificate (PG Cert): 4 months full-time 1 year part-time (minimum 5-maximum 12 months continuous enrolment)

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D - Programme Specification (Master’s Level)

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Postgraduate Certificate, Postgraduate Diploma / MSc in Genomic Medicine

This document provides a definitive record of the main features of the programme and the learning outcomes that a typical student may reasonably be expected to achieve and demonstrate if s/he takes full advantage of the learning opportunities provided. This programme specification is primarily intended as a reference point for academic and support staff involved in delivering the programme and enabling student development and achievement, for its assessment by internal and external examiners, and in subsequent monitoring and review.

Programme Information

Award Postgraduate Certificate / Postgraduate Diploma / MSc

Programme Title Genomic Medicine

Programme code

A3GM A3GM24 A3GM2M A3GC4 A3GC12 A3GC1M A3GC4M A3GD8 A3GD24

Awarding Institution Imperial College London

Teaching Institution Imperial College London

Faculty Faculty of Medicine

Department National Heart and Lung Institute (NHLI)

Mode and Period of Study

This is a modular, flexible programme. For MSc: 1 year full-time (12 months) 2 years part-time (24 months) For PG Diploma (PG Dip): 8 months full-time 2 years part-time (minimum 9-maximum 24 months continuous enrolment) For PG Certificate (PG Cert): 4 months full-time 1 year part-time (minimum 5-maximum 12 months continuous enrolment)

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Cohort Entry Points

Annually in October for full-time MSc. Annually in October and March for part-time MSc. Annually in October for full-time PG Dip. Annually in October and March for part-time PG Dip. Annually in October and March for full-time and part-time PG Cert. Students who have already completed the PG Cert can register for direct entry on to either the part-time or full-time PG Diploma or the full-time MSc at an appropriate time to be agreed by the Programme Director. Students who have already completed the PG Dip can register for direct entry on to the part-time or full-time MSc in at an appropriate time to be agreed by the Programme Director (noting that certain laboratory based projects may only be available over the summer – between June and October). Within the maximum period allowed for registration – see below, students will have a minimum of 4 months (if full-time) or 12 months, if part-time, to complete their project.

Relevant QAA Benchmark Statement(s) and/or other external reference points

There is no Master’s level subject benchmark statement specialty encompassed by this programme, however, the programme has been designed in line with the requirements of Health Education England, the NHS, and Genomics England Ltd.

Total Credits ECTS: MSc: 90 PG Dip: 60 PG Cert: 30

CATS Credit:

MSc: 180 PG Dip: 120 PG Cert: 60

FHEQ Level Level 7 - Master’s

EHEA Level 2nd cycle

External Accreditor(s)

Specification Details

Student cohorts covered by specification 2015-16

Responsible Officer Professor Michael Lovett, NHLI

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Date of introduction of programme 10/2015

Date of programme specification/revision 10/2015

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Description of Programme Contents

This clinical Master’s level programme will educate students from a wide range of backgrounds (e.g. medicine, nursing, healthcare scientists and technologists) to interpret and understand genomic DNA data that increasingly impacts on service delivery to patients. The programme is flexible and modular and includes full- and part-time MSc options, delivered over one or two years respectively. There are also full-time and part-time Postgraduate Certificate (PG Cert) or Postgraduate Diploma (PG Dip) options. If choosing the full-time PG Cert or PG Diploma mode of study students should be aware that module choices will be limited. Students will be made aware of their options during the admissions process. The aim of the programme is to enhance knowledge and skills in this rapidly evolving field by providing a flexible, multi-disciplinary and multi-professional perspective in genomics as applied to clinical practice and medical research. In so doing, it fulfils the requirements of Genomics England, Health Education England and Public Health England for MSc, PG Dip and PG Cert programmes to transform the NHS workforce in readiness for the 100 Thousand Genomes Project, set out in a tender in 2014. Imperial College was successful in its bid to run the programmes and has been designated a preferred provider by Health Education England. The programme comprises core and optional taught modules of 7.5 ECTS each that will be taught using a blended approach (direct teaching and online distance learning) to provide flexibility for health professionals to combine their study with NHS and Public Health service duties. The MSc programme also includes a core research module (30 ECTS) with opportunities to access the emerging data from the 100,000 Genomes Project through the Genomics England Clinical Interpretation Partnership (GeCIP) training domains. Most modules will consist of one week of face-to face teaching and up to three weeks of eLearning and independent study (exceptions are noted below). The modules are offered on a cycle of 12 months, so that all modules become available at least once in each 12 month cycle. The core module “Core Concepts in Human Genetics & Genomics” which all students must take is offered twice in each 12 month cycle and the optional module Work-Based

Learning modules can be taken by students at any time as agreed with the Programme Director. The programme includes collaborations with the Institute for Cancer Research (providing the core Cancer Genomics Module), Buckinghamshire New University (collaborating on the optional Workplace-Based Module), and Brunel University London (providing the optional Economic Evaluation in Human Genomics Module). The Institute of Cancer Research and Brunel may also co-supervise research projects. Brief module outlines

Core taught modules The Core Concepts in Human Genetics & Genomics Module will provide all of the basic genomic science knowledge required by later modules including genomic architecture, regulatory systems, genetic variation, function and how this impacts upon disease processes and clinical outcomes. The Omics Technologies & their Application to Genomic Medicine Module will provide an in depth description of the genomic techniques that are used to assess genomic variation in clinical problems. It will allow the students to critically evaluate which techniques might be used and their limitations in analysing different disease states.

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The Application of Genomics in Infectious Diseases Module will explain how pathogen genomics can inform the epidemiology of infections, impact upon drug development and resistance, lead to novel diagnostics/therapeutics/stratified healthcare, and provide insights into host susceptibilities to infection. The Molecular Pathology of Cancer Application in Diagnosis, Screening and Treatment Module will explain the principles of cancer genomics, including predisposition, diagnosis, classification, treatment and patient monitoring with particular emphasis on how genomic analysis impacts these factors and the ethical issues relevant to cancer. The Ethics, Legal and Social Issues in Applied Genomic Module will explain the principles and subtleties of ethics in evaluating genetic/genomic data with an emphasis on emerging genomics technologies and the ways that ethics issues are handled in various countries. The Common and Rate Inherited Diseases Module will explain different types of genetic variation, their contribution to rare and complex disease, how they are detected (with particular emphasis upon the 100,000 Genomes Project), interpreted and communicated. The Bioinformatics, Quality Control, Analysis and Interpretation of Genome Sequencing Data Module will provide the principles of computational DNA sequence analysis, including sequence alignment methods and statistical tests, to identify and correctly communicate pathogenic mutations and assess possible functions through database and network programs. The Genomics and the Patient Module is a less computationally intense alternative to the bioinformatics module and will concentrate on the identification and interpretation of final Next Gen DNA sequencing reports with an emphasis on calculating genetic risk and ethical considerations, Optional taught modules The Pharmacogenomics and Stratified Medicine Module will explain how genomic approaches can be used to understand the mechanisms of differential drug responses and reactions, and to inform patient stratification. An emphasis will be placed upon the current limitations and future prospects of pharmacogenomic studies. The Economic Evaluation in Human Genomics module will explain the methods, assumptions, decision models, and interpretation of, cost estimate analysis, for healthcare interventions and health outcomes, with a particular emphasis on genomic medicine The Laboratory Skills for Genomics Module will be a hands-on wet lab course on how to develop a good experimental design, carry out a genomic analysis project, identify and critically analyse sequence variants and determine the implications for patients. The Genome-Based Therapeutics Module will cover key concepts in developing gene and nucleic acid-based therapies from genomic studies including efficacy and toxicity. The Professional and Research Skills E-Learning Module will teach the differences between audit, research, qualitative, quantitative and systematic review methods, how to conduct literature searches, appraise published data, conduct appropriate statistical tests and understand the data management, ethical and reporting requirements in research studies, with a particular emphasis on the 100,000 Genomes Project and translational research. The Workplace-based Learning Module will be conducted with a clinical mentor and a genomics expert. It will focus upon developing a learning contract and a proposed change in clinical practice enabled by genomic medicine approaches and the integration of new knowledge. It will incorporate an evaluation of personal/organizational issues, the application of genomic methods to a range of cases and an evaluation of their utility. Students complete this module in their own workplace therefore it will only be available to students who work in an appropriate healthcare setting (to be approved by the module co-leads). Core Research Project (MSc students only) The Research Project is the final core requirement for the MSc programme and will involve identifying a novel and important research question, designing, planning and undertaking the project, critically

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analyzing and drawing statistically substantiated conclusions from the data. Assessment is by written dissertation, oral presentations and supervisor mark. Four types of project are offered: laboratory-, clinical-, computer- or literature-based. MSc, PG Dip and PG Cert programmes Full-time students should register for the qualification they wish to exit with, either PG Cert, PG Dip or MSc. Part-time students should register for the PG Cert in the first instance and progress to the other awards should they so wish. MSc programme All MSc students are required to take 8 taught modules plus an independent research project. In total students will complete 7 core modules and 1 optional/elective module from a choice of 6. Core Modules Core Concepts in Human Genetics and Genomics Omics Technologies and their Application to Genomic Medicine Application of Genomics in Infectious Disease Molecular Pathology of Cancer and Application in Cancer Diagnosis, Screening and Treatment (delivered by the Institute of Cancer Research) Ethical, Legal and Social Issues in Applied Genomics Genomics of Common and Rare Inherited Diseases Either Bioinformatics, Quality Control, Analysis & Interpretation of Genome Sequencing Data OR Genomics and the Patient Elective/Optional Modules* Pharmacogenomics and Stratified Medicine Economic Evaluation in Human Genomics (delivered by Brunel University London) Laboratory Skills for Genomics Genome-Based Therapeutics Professional and Research Skills (eLearning module) Workplace-Based Module (all distance learning) (co-delivered with Buckingham New University) PG Dip programme All PG Dip students are required to take 8 taught modules (which will include either Bioinformatics, Quality Control, Analysis & Interpretation of Genome Sequencing Data or Genomics and the Patient, but not both). In total students will complete all 7 core modules and 1 optional module from a choice of 6 as shown above. PG Cert programme All PG Cert students are required to take 4 taught modules (which may include either Bioinformatics, Quality Control, Analysis & Interpretation of Genome Sequencing Data or Genomics and the Patient, but not both). In total students must complete the Core Concepts module and 3 further modules, 1 of which can be from the optional list above. *Please note: Students will be provided with information prior to enrolment to help them make modules and mode of study choice which will best suit their study and career ambitions. It is intended to offer each module at least once in every 12 month cycle so students opting for the full-time Postgraduate Certificate and Postgraduate Diploma may be limited in their option choices. Some optional modules may not run if there is not enough demand.

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Learning Outcomes

On graduation, all students will be able to: PG Cert

Critically appraise and synthesise genomic medicine data from a range of sources

Communicate core concepts in genomic medicine clearly and effectively with both scientifically-literate and lay audiences

Evaluate the potential of large-scale patient genome analysis to revolutionise healthcare in at least one domain

Self-critique by reflecting on coursework evaluation, project reports, critical reviews of scientific papers.

PG Dip Learning Objectives for the PG Cert plus

Evaluate the potential of large-scale patient genome analysis to revolutionise healthcare across inherited disease, cancer and infectious disease and its implications in the healthcare setting

Demonstrate awareness of the societal and ethical context of genomic medicine, including the complexities of protecting patient information

Critically evaluate strengths and limitations of techniques suitable for assessing genomic variation relating to different clinical problems and disease states.

Demonstrate competency in analysing and interpreting patient genomic analysis results and communicating their implications effectively to the patient.

MSc Learning Objectives for PG Cert and PG Dip plus

Demonstrate synoptic knowledge and deep understanding of medical genomics

Deploy effective problem-solving strategies in data analysis and experimental design

Appreciate the success, failure and the uncertainty inherent in research

Effectively communicate scientific information in both written and oral forms

Use project management skills in the context of the research project

Select and deploy suitable research resources and strategies

Synthesise complex research findings into a clear dissertation and oral presentation

Entry Requirements

Academic Requirement Normally a 2:1 UK Bachelor’s Degree (or equivalent) in a relevant medical, biomedical or healthcare subject.

Additional Requirements

Information for students who already hold the PG Cert or PG Diploma: For the direct entry route to the PG Diploma students wishing to attend on a full-time or part-time basis will have to have successfully completed the PG Cert. For the direct entry route to the MSc, students wishing to attend on a part-time basis will have to have successfully completed the PG Diploma

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For the direct entry route to the MSc, students wishing to attend on a full-time basis will have to have completed either the PG Cert or PG Diploma as appropriate

Applicants who do not meet the academic requirements above but who have substantial relevant healthcare experience may be admitted following completion of a ‘Special Qualifying Exam’ (SQE).

All shortlisted applicants will be interviewed (via Skype).

English Requirement Standard requirement - IELTS 6.5 with no element below 6.0 (or equivalent)

Learning & Teaching Strategy

Scheduled Learning & Teaching Methods

Lectures, seminars, keynote lectures, problem-based group work, journal clubs, debates, discussion sessions laboratory teaching, data analysis sessions, computer lab teaching.

E-learning & Blended Learning Methods

Online platform on Blackboard including: module leader introductory video, self-tests at the beginning and end, a primer setting out pre-reading and key concepts, lecture recordings of face-to-face sessions, discussion board and frequently asked questions dropbox for module leader. Game-based online Virtual Patients’ Genomic Journeys chapter (most modules): students trial decision-making theory in practice, learning from the ensuing consequences encountered. Online chapters: filmed lectures, animated diagrams, quizzes, voice-overs, collated resources, discussion boards, reflective logs and case studies. Students also have the option of taking a solely online e-learning module “Professional and Research Skills” which will consist of 12 online chapters.

Project and Placement Learning Methods

MSc students are required to complete a research project, which will include: scheduled supervision tutorials weekly, ongoing bench supervision (aided by research group members), laboratory group discussions, laboratory group presentations, journal clubs, technical instruction, equipment training, health and safety teaching, data analysis, literature research. Students have the option to take a Workplace-based Learning Module in their own workplace, which will include six hours of scheduled face-to-face tutorials with an academic supervisor.

Assessment Strategy

Assessment Methods

Assessment is designed to align with Learning Outcomes for each module and to be balanced equally across all taught modules with respect to student effort and timing of assessments.

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Taught modules will be assessed by coursework alone (9 modules), examination and coursework (3 modules), practical assessment and coursework (1 module) or examination and practical assessment (1 module). Students will therefore be assessed via a range of assessment methods. Choice of modules will be agreed with the Programme Director. Coursework assessment includes : Critical analysis of complex clinical data sets/case studies Completion of ethical approval form Critical analysis of clinical diagnostic reports Report on analysis of bioinformatics data Lay summary of the 100,000 Genomes Project Protocol suitable for delivering DNA sequence findings to patients Critical appraisal of published evaluation Report of experimental findings written as a research paper Research proposal Report on clinical practice development Review article written for “Bioessays” format Examination format: 1-hour: Single Best Answer & Short Answer Question sections 2-hour: Short Answer Question section and long essay Practical assessment: Deliver analysed genomic data to a simulated patient (actor) Critical analysis of a research paper, presented orally to a group The MSc research project is largely assessed by a written report. Assessment also includes a presentation to a mixed student & lay audience, an oral assessment with two internal examiners and supervisor assessment of research and analytical skills.

Academic Feedback Policy

Feedback will be appropriately tailored for the type of assessment and will be provided in a timely manner. The exact turnaround time will depend upon the length and complexity of the submission, but will normally be within two weeks. Where it is longer, students will be told when they may expect to receive their feedback.

Re-sit Policy

Students will be permitted to re-enter a failed examination on a single occasion. Resits will be scheduled in August of each year. At the discretion of the Programme Director, students may be counselled to wait until the following year to re-sit. A failed piece of coursework can be resubmitted on one occasion, with a deadline to be agreed with the relevant module leader and Programme Director, normally between 1 week and 2 months after the original submission deadline.

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If the MSc research project is failed, students may resubmit on one occasion in the following academic year, with a deadline to be agreed with their project supervisor and the Programme Director. Re-sitting/re-submitting assessments will normally be capped at the pass mark.

Mitigating Circumstances Policy

Candidates with mitigating circumstances will be dealt with according to the relevant College policy https://workspace.imperial.ac.uk/registry/Public/Exams/MitigatingCircumstancesPolicyProcedures-Feb%202014.pdf

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D - Programme Specification (Master’s Level)

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Programme Structure

Module timings [bold type = Core; normal type = Optional]

Autumn Term ECTS Spring Term ECTS Summer Term ECTS Summer Term/Summer ECTS

Core Concepts in Human Genetics & Genomics (for October starters)

7.5 Core Concepts in Human Genetics & Genomics (for March starters)

7.5 Genomics of Common and Rare Inherited Diseases

7.5 Research Project 30

Omics Technologies and their Application to Genomic Medicine

7.5 Molecular Pathology of Cancer and Application in Cancer Diagnosis, Screening and Treatment (Inst. of Cancer Res)

7.5 Bioinformatics, Quality Control, Analysis and Interpretation of Genome Sequencing Data OR Genomics and the Patient

7.5

Application of Genomics in Infectious Disease

7.5 Ethical Legal and Social Issues in Applied Genomics

7.5 Genome Based Therapeutics

7.5

Pharmacogenomics and Stratified Medicine

7.5

Economic Evaluation in Human Genomics (Brunel)

7.5

Laboratory Skills for Genomics 7.5

Further Elective Modules (can be taken at any time, in place of one of the elective modules above)

Professional and Research Skills 7.5 ECTS Workplace Based Learning 7.5 ECTS (co-delivered by Imperial and Bucks New University)

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Programme Structure and Module Choice for Full-time MSc students (October only)

Autumn Term 3 Core Modules – students may choose to take one of the further elective modules listed above.

Spring Term 2 Core Modules & 3 Elective Modules – students must study either the Bioinformatics OR Genomics and the Patient module (not both); students may choose one elective module (if they have not already completed either the Professional & Research Skills Module or the Workplace Based Learning Module in the Autumn Term).

Summer Term 2 Core Modules & 1 Elective Module – students may choose the summer elective module if they have not already taken an elective module in a previous term. (Note that students taking the summer elective module can make a start on their Research Project in the Spring Term elective slot.)

Summer Term/Summer 1 Research Project (Core) – Students commence their Research Project during the Summer Term and submit in September.

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D - Programme Specification (Master’s Level)

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Assessment Dates & Deadlines

Written Examinations

Two modules include a written examination as part of the assessment. Exams will be scheduled at the beginning of the term following the module: Omics Technologies and their Application to Genomic Medicine (November) Application of Genomics in Infectious Disease (December)

Coursework Assessments All modules will include coursework assessment, with deadlines usually set three weeks after the end of the face-to-face teaching week

Project Deadlines – MSc students only

Mid-September for full-time October starters Mid-October for part-time March starters Part-time students would normally be expected to complete their MSc project within 12 months.

Practical Assessments

Genomics and the Patient has one practical assessment (May, in module). Genome-based therapeutics includes an oral presentation (March, in module). Pharmacogenomics and Stratified Medicine includes an oral presentation (March, in module). Research project includes an oral presentation to a mixed audience and an oral assessment with two internal examiners (September)

Assessment Structure for MSc

Programme Elements ECTS % Weighting

PG Certificate (4 x taught modules) – all modules are equally weighted Additionally, all students must pass a zero weighted, not for credit, on-line Primer for Genomics course

30 33%

Additional 4 modules for PG Diploma – all modules are equally weighted

30 33%

Research project – consisting of written report (75%), oral presentation (10%) and oral assessment with two internal examiners (10%), and supervisor assessment of research skills and analytical ability demonstrated during the research project (5%)

30 34%

Total 90 100%

Assessment Structure for the PG Certificate

Programme Elements ECTS % Weighting

4 x taught modules – all modules are equally weighted 30 100%

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Additionally, all students must pass a zero weighted, not for credit, on-line Primer for Genomics course

Total 30 100%

Assessment Structure for the PG Diploma

Programme Elements ECTS % Weighting

4 x taught modules for the PG Certificate – all modules are equally weighted Additionally, all students must pass a zero weighted, not for credit, on-line Primer for Genomics course

30 50%

4 x taught modules - all modules are equally weighted 30 50%

Total 60 100%

Rules of Progression

Full-time students register for the qualification they wish to exit with: PG Cert, PG Dip or MSc programme. Part-time students should register for the PG Certificate in the first instance and progress to the other awards should they so wish. Students registered for the PG Cert who wish to continue on the programme without a break can transfer their registration to the PG Dip after completing Core Concepts and 2 other modules, provided they have demonstrated satisfactory academic progress in their first 3 modules. Similarly, students registered for the PG Dip can transfer their registration to the MSc after completing two further modules, provided they have demonstrated satisfactory academic progress. Satisfactory progress will normally be judged achieving at least 50% for module assessments completed. PG Cert students who have failed a single module with a mark between 45-49% may still transfer their registration to PG Dip, subject to confirmation on passing the failed coursework and/or exam on the second and final attempt. The same applies to PG Dip students who have failed one of their two post-PG Cert modules. Students who register for and successfully complete the PG Cert may use the credit gained towards registration for the PG Dip or the MSc at a later point, provided that the PG Dip is completed within 4 years and the MSc is completed within 5 years, of initial registration for the Postgraduate Certificate. These students may be asked to surrender the associated PG Cert and/or PG Diploma on registration for the higher award. Likewise, students who register for and successfully complete the PG Dip may use the credit gained towards the MSc, provided that the MSc is completed within 5 years of their initial registration of the lowest award. These students may be asked to surrender the associated PG Dip on registration for the MSc. Students who register for the MSc in the first instance will have a “virtual” PG Cert confirmed if the requirements for the PG Cert have been met. The pass mark for the PG Cert will be carried forward and the credits will accumulate towards the next level. On successful completion of eight modules (seven Core and one Optional), students will have a “virtual” PG Dip. The pass mark will be carried

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forward and the credits will accumulate towards the MSc. Should these students subsequently fail to achieve the requirements for the MSc they will be awarded the PG Dip. The pass mark for each module is 50%. Within a module, no assessment less than 40% will be considered as a condoned pass regardless of the aggregate mark for the module. PG Cert: Students may be permitted one module marginal fail (45%-49%), but must pass the other three modules and achieve an overall aggregate score of 50% in order to pass the PG Cert. PG Dip: Students may be permitted two module marginal fail (45%-49%) but, in total, must pass six modules. MSc: Students who have already completed the taught pathway must pass the research project module (with a minimum aggregate mark of 50%) in order to be awarded the MSc. Students may be permitted a marginal fail (45-49%) in one of the oral presentation elements and or the supervisor assessment as long as they achieve a mark of 50% or above in the research dissertation, and their aggregate mark for the project is 50% or above.

Marking Scheme

Clear criteria for marking written work, oral presentations and research dissertations will be used for assessments across all modules to ensure consistency in marking and requirements for Pass, Merit and Distinction grades. MSc The MSc assessments are grouped into three elements as shown in the overall table of assessments above. Students must pass all three elements to graduate. One agreed mark will be returned for each element. Provided a candidate has achieved at least 50% in each of the elements, they will be awarded a result of pass. In order to be awarded a result of merit, a candidate must achieve at least 60% in each element, in order to be awarded a result of distinction, a candidate must achieve at least 70% in each element. The Board of Examiners may award a result of merit where a candidate has achieved an aggregate mark of 60% or greater across the programme as a whole AND has obtained a mark of 60% or greater in each element with the exception of one element AND has obtained a mark of 50% or greater in this latter element. The Board of Examiners may award a result of distinction where a candidate has achieved an aggregate mark of 70% or greater across the programme as a whole AND has obtained a mark of 70% or greater in each element with the exception of one element AND has obtained a mark of 60% or greater in this latter element. The Postgraduate Certificate and Postgraduate Diploma are not classified. Candidates will normally only be considered for promotion to pass, (or for merit or distinction for MSc awards) if their aggregate mark is within 2.5% of the relevant borderline. Candidates whom the Board of Examiners deems to have exceptional circumstances may be considered for promotion even if their aggregate mark is more than 2.5% from the borderline. In such cases the necessary

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extra marks will be credited to bring the candidate’s aggregate mark into the higher range. A viva will normally be called to examine students who are being considered for promotion to a higher degree classification. The Board of Examiners will comprise the Programme Director, Programme Organiser, all Module Leaders and External Examiners.

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Module List

Code Title Core/

Elective Year

L&T Hours

Ind. Study Hours

Place- ment Hours

Total Hours

% Written

Exam

% Course-

work

% Practical

FHEQ Level

ECTS

Core Concepts in Human Genetics and Genomics

Core 1 30 157.5 0 187.5 0 100 0 6 7.5

Omics Technologies and their Application to Genomic Medicine

Core 1 30 157.5 0 187.5 40 60 0 7 7.5

Application of Genomics in Infectious Disease

Core 1 30 157.5 0 187.5 40 60 0 7 7.5

Molecular Pathology of Cancer and Application in Cancer Diagnosis, Screening and Treatment (ICR)

Core 1 30 157.5 0 187.5 0 100 0 7 7.5

Ethical, Legal and Social Issues in Applied Genomics

Core 1 30 157.5 0 187.5 0 100 0 7 7.5

Pharmacogenomics and Stratified Medicine Elective 1 30 157.5 0 187.5 60 40 0 7 7.5

Economic Evaluation in Human Genomics (Brunel)

Elective 1 30 157.5 0 187.5 0 100 0 7 7.5

Laboratory Skills for Genomics Elective 1 60 127.5 0 187.5 0 100 0 7 7.5

Genomics of Common and Rare Inherited Diseases

Core 1 30 157.5 0 187.5 0 100 0 7 7.5

Bioinformatics, Quality Control, Analysis & Interpretation of Genome Sequencing Data

Core 1 30 157.5 0 187.5 0 100 0 7 7.5

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Module List

Code Title Core/

Elective Year

L&T Hours

Ind. Study Hours

Place- ment Hours

Total Hours

% Written

Exam

% Course-

work

% Practical

FHEQ Level

ECTS

Genomics and the Patient Core 1 30 157.5 0 187.5 0 50 50 7 7.5

Genome Based Therapeutics Elective 1 30 157.5 0 187.5 60 40 0 7 7.5

Research project Core 1 490 260 0 750 0 75 25 7 30

Professional and Research Skills Elective 1 0 187.5 0 187.5 0 100 0 7 7.5

Workplace-based Learning Elective 1 10 127.5 50 187.5 0 100 0 7 7.5

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Supporting Information

The Programme Handbook is available at: TBC

The Module Handbook is available at: TBC

The programme’s competency standards documents can be found at: TBC

The College’s entry requirements for postgraduate programmes can be found at: http://www3.imperial.ac.uk/entryrequirements/graduate

The College statement on pastoral care and welfare support is available at: TBC

Details of Departmental arrangements for pastoral care and welfare support is available at: TBC

The College’s Quality & Enhancement Framework is available at: http://www3.imperial.ac.uk/registry/proceduresandregulations/qualityassurance

The programme is consistent with the Qualifications Framework of the European Higher Education Area which is available at: http://www.ehea.info/Uploads/qualification/QF-EHEA-May2005.pdf