powerful decision-making tools in medical …...an emerging micro-scale immuno-analytical diagnostic...
TRANSCRIPT
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Powerful Decision-Making Tools in Medical-Pharmaceutical Issues
Chemical, Biochemical, Cellular, Subcellular
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BIOANALYTICAL CHEMISTRY
IMMUNOAFFINITY CAPILLARY ELECTROPHORESIS
EBF-2016
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CONCLUSIONS 1. We are experiencing an unprecedented acceleration in the speed at which
breakthrough therapies arise from basic scientific discovery.
2. Bioanalysis platforms are crucial to monitor biomarkers of relevance to diagnosis,
prognosis and effectiveness of therapy.
3. Immunoaffinity capillary electrophoresis provides a rapid analysis of the fate of
drug products and the determination of a panel of biomarkers in biosamples.
4. The technique is simple, cost effective, and yields precise and accurate results.
5. Coupled to powerful detectors IACE becomes a very sensitive tool and facilitates
the characterization of the intact drug, degradation products (PTMs), metabolites
and isoforms.
EBF-2016 Journal of Chromatography B, 1021 (2016) 14–29
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EBF-2016