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Practical Neuroanatomy Practical Neuroanatomy Lecture 1 Lecture 1 Overview Overview Christine Hulette MD Christine Hulette MD [email protected] [email protected] 684-3801 684-3801 M214C Green Zone Duke South M214C Green Zone Duke South Leibman’s Neuroanatomy Made Easy and Leibman’s Neuroanatomy Made Easy and Understandable Understandable pages 1-9;76-88 pages 1-9;76-88

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Practical NeuroanatomyPractical NeuroanatomyLecture 1 Lecture 1 OverviewOverview

Practical NeuroanatomyPractical NeuroanatomyLecture 1 Lecture 1 OverviewOverview

Christine Hulette MDChristine Hulette MD

[email protected]@mc.duke.edu

684-3801684-3801

M214C Green Zone Duke SouthM214C Green Zone Duke South

Leibman’s Neuroanatomy Made Easy and UnderstandableLeibman’s Neuroanatomy Made Easy and Understandable

pages 1-9;76-88pages 1-9;76-88

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EpendymaEpendymaEpendymaEpendyma

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White MatterWhite MatterWhite MatterWhite Matter

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CENTRAL NERVOUS SYSTEMCENTRAL NERVOUS SYSTEMBrain and Spinal CordBrain and Spinal Cord

PERIPERAL NERVOUS SYSTEMPERIPERAL NERVOUS SYSTEMCranial Nerves, Motor and SensoryCranial Nerves, Motor and SensorySpinal Nerves, Motor and SensorySpinal Nerves, Motor and Sensory

GangliaGangliaMotor End PlateMotor End Plate

Sensory ReceptorsSensory ReceptorsAutonomic Nervous SystemAutonomic Nervous System

CENTRAL NERVOUS SYSTEMCENTRAL NERVOUS SYSTEMBrain and Spinal CordBrain and Spinal Cord

PERIPERAL NERVOUS SYSTEMPERIPERAL NERVOUS SYSTEMCranial Nerves, Motor and SensoryCranial Nerves, Motor and SensorySpinal Nerves, Motor and SensorySpinal Nerves, Motor and Sensory

GangliaGangliaMotor End PlateMotor End Plate

Sensory ReceptorsSensory ReceptorsAutonomic Nervous SystemAutonomic Nervous System

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Cells Of The Nervous SystemCells Of The Nervous System Cells Of The Nervous SystemCells Of The Nervous System NeuronsNeurons

AxonAxon Dendrite Dendrite SynapseSynapse

Supporting CellsSupporting Cells Central Nervous SystemCentral Nervous System

AstrocytesAstrocytes OligodendrogliaOligodendroglia MicrogliaMicroglia EpendymaEpendyma

Peripheral Nervous SystemPeripheral Nervous System Satellite CellsSatellite Cells Schwann CellsSchwann Cells

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TELENCEPHALONTELENCEPHALON

Cerebral HemispheresCerebral HemispheresBasal GangliaBasal Ganglia

TELENCEPHALONTELENCEPHALON

Cerebral HemispheresCerebral HemispheresBasal GangliaBasal Ganglia

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DIENCEPHALONDIENCEPHALON

ThalamusThalamusHypothalamusHypothalamusEpithalamusEpithalamus

DIENCEPHALONDIENCEPHALON

ThalamusThalamusHypothalamusHypothalamusEpithalamusEpithalamus

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EPITHALAMUSEPITHALAMUS

PinealPinealHabenulaHabenula

EPITHALAMUSEPITHALAMUS

PinealPinealHabenulaHabenula

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MESENCEPHALONMESENCEPHALON

Tectum (superior)Tectum (superior)Tegmentum (inferior)Tegmentum (inferior)

Cranial nerve III, IV nucleiCranial nerve III, IV nucleiRed NucleusRed Nucleus

Substantia NigraSubstantia NigraCerebral PeduncleCerebral Peduncle

MESENCEPHALONMESENCEPHALON

Tectum (superior)Tectum (superior)Tegmentum (inferior)Tegmentum (inferior)

Cranial nerve III, IV nucleiCranial nerve III, IV nucleiRed NucleusRed Nucleus

Substantia NigraSubstantia NigraCerebral PeduncleCerebral Peduncle

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PONS AND CEREBELLUMPONS AND CEREBELLUM

Archicerebellum- maintains equilibriumArchicerebellum- maintains equilibriumPaleocerebellum- maintains muscle tonePaleocerebellum- maintains muscle tone

Neocerebellum- controls coordinationNeocerebellum- controls coordinationPons - bridgePons - bridge

Cranial nerves V, VI, VIICranial nerves V, VI, VII

PONS AND CEREBELLUMPONS AND CEREBELLUM

Archicerebellum- maintains equilibriumArchicerebellum- maintains equilibriumPaleocerebellum- maintains muscle tonePaleocerebellum- maintains muscle tone

Neocerebellum- controls coordinationNeocerebellum- controls coordinationPons - bridgePons - bridge

Cranial nerves V, VI, VIICranial nerves V, VI, VII

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MEDULLAMEDULLA

Cranial nerves VIII through XIICranial nerves VIII through XIIPyramidsPyramids

Inferior OlivesInferior Olives

MEDULLAMEDULLA

Cranial nerves VIII through XIICranial nerves VIII through XIIPyramidsPyramids

Inferior OlivesInferior Olives

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SPINAL CORDSPINAL CORD

Dorsal (posterior) - proprioceptionDorsal (posterior) - proprioceptionLateral - corticospinal tractLateral - corticospinal tract

Ventral (anterior horn) - lower motor Ventral (anterior horn) - lower motor neuronsneurons

Spinal NervesSpinal Nerves

SPINAL CORDSPINAL CORD

Dorsal (posterior) - proprioceptionDorsal (posterior) - proprioceptionLateral - corticospinal tractLateral - corticospinal tract

Ventral (anterior horn) - lower motor Ventral (anterior horn) - lower motor neuronsneurons

Spinal NervesSpinal Nerves

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BRODMANN AREASBRODMANN AREASBRODMANN AREASBRODMANN AREAS

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MAJOR COVERINGSMAJOR COVERINGSSKULL AND MENINGESSKULL AND MENINGES

MAJOR COVERINGSMAJOR COVERINGSSKULL AND MENINGESSKULL AND MENINGES

ScalpScalp

SkullSkull

Dura MaterDura Mater

Arachnoid MaterArachnoid Mater

Pia MaterPia Mater

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BLOOD SUPPLYBLOOD SUPPLYBLOOD SUPPLYBLOOD SUPPLY

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CEREBROSPIONAL FLUID AND CEREBROSPIONAL FLUID AND VENTRICLESVENTRICLES

CEREBROSPIONAL FLUID AND CEREBROSPIONAL FLUID AND VENTRICLESVENTRICLES

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MICROSCOPIC NEUROHISTOLOGYMICROSCOPIC NEUROHISTOLOGYMAJOR SYSTEMSMAJOR SYSTEMS

TELENCEPHALONTELENCEPHALONDIENCEPHALALONDIENCEPHALALONMESENCEPHALONMESENCEPHALON

CEREBELLUM AND PONSCEREBELLUM AND PONSMEDULLAMEDULLA

SPINAL CORDSPINAL CORDBRODMANN AREASBRODMANN AREAS

SKULL AND MENINGESSKULL AND MENINGESBLOOD SUPPLYBLOOD SUPPLY

CERBROSPINAL FLUIDCERBROSPINAL FLUID

MICROSCOPIC NEUROHISTOLOGYMICROSCOPIC NEUROHISTOLOGYMAJOR SYSTEMSMAJOR SYSTEMS

TELENCEPHALONTELENCEPHALONDIENCEPHALALONDIENCEPHALALONMESENCEPHALONMESENCEPHALON

CEREBELLUM AND PONSCEREBELLUM AND PONSMEDULLAMEDULLA

SPINAL CORDSPINAL CORDBRODMANN AREASBRODMANN AREAS

SKULL AND MENINGESSKULL AND MENINGESBLOOD SUPPLYBLOOD SUPPLY

CERBROSPINAL FLUIDCERBROSPINAL FLUID