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Page 1: [PPT]Mendel's genetics - Miss Lee's 7th Grade Science Classsequoyahscience.weebly.com/uploads/3/8/9/3/38939833/mend... · Web viewAuthor Cheryl Massengale Created Date 02/26/2000

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Mendelelian Genetics

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Page 2: [PPT]Mendel's genetics - Miss Lee's 7th Grade Science Classsequoyahscience.weebly.com/uploads/3/8/9/3/38939833/mend... · Web viewAuthor Cheryl Massengale Created Date 02/26/2000

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Gregor Mendel

(1822-1884)Responsible for the Laws governing

Inheritance of Traits

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Gregor Johann MendelAustrian monkStudied the inheritance of traits in pea plantsDeveloped the laws of inheritanceMendel's work was not recognized until the turn of the 20th century copyright cmassengale

Page 4: [PPT]Mendel's genetics - Miss Lee's 7th Grade Science Classsequoyahscience.weebly.com/uploads/3/8/9/3/38939833/mend... · Web viewAuthor Cheryl Massengale Created Date 02/26/2000

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Gregor Johann MendelBetween 1856 and 1863, Mendel cultivated and tested some 28,000 pea plantsHe found that the plants' offspring retained traits of the parentsCalled the “Father of Genetics"

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Site of Gregor Mendel’s experimental garden in the Czech Republic

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Mendel stated that physical traits are inherited as “particles”Mendel did not know that the “particles” were actually Chromosomes & DNA

Particulate Inheritance

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Genetic Terminology Trait - any characteristic that can be passed from parent to offspring

Heredity - passing of traits from parent to offspring

Genetics - study of heredity

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Use Your Noodle!Answer the following in your science notebook.

What traits are found in your family?

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You have 2 minutes

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Types of Genetic Crosses

Monohybrid cross - cross involving a single traite.g. flower color

Dihybrid cross - cross involving two traits e.g. flower color & plant height

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YOU NEED A PENCIL FOR

TODAY’S ACTIVITY!copyright cmassengale 10

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Designer “Genes” Alleles - two forms of a gene

(dominant & recessive) Dominant - stronger of two

genes expressed in the hybrid; represented by a capital letter (R)

Recessive - gene that shows up less often in a cross; represented by a lowercase letter (r) copyright cmassengale

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More Terminology Genotype - gene combination for a trait (e.g. RR, Rr, rr)

Phenotype - the physical feature resulting from a genotype (e.g. red, white)

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Genotype & Phenotype in Flowers

Genotype of alleles:R = red flowerr = yellow flowerAll genes occur in pairs, so 2 alleles affect a characteristicPossible combinations are:Genotypes RR Rr rrPhenotypesRED RED YELLOW

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Use Your Noodle!Answer the following in

your science notebook.

Determine which allele is dominate and recessive?

RrGGHhff

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You have 2 minutes

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Genotypes Homozygous genotype - gene

combination involving 2 dominant or 2 recessive genes (e.g. RR or rr); also called pure 

Heterozygous genotype - gene combination of one dominant & one recessive allele    (e.g. Rr); also called hybrid copyright cmassengale

Page 16: [PPT]Mendel's genetics - Miss Lee's 7th Grade Science Classsequoyahscience.weebly.com/uploads/3/8/9/3/38939833/mend... · Web viewAuthor Cheryl Massengale Created Date 02/26/2000

Use Your Noodle!Answer the following in

your science notebook.

Determine which allele is Homozygous or Heterozygous?

RrGGHhff

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You have 2 minutes

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Genes and Environment Determine Characteristics

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Mendel’s Pea Plant

Experiments

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Why peas, Pisum sativum?

Can be grown in a small area Produce lots of offspring Produce pure plants when allowed to self-pollinate several generations Can be artificially cross-pollinated copyright cmassengale

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Mendel’s Experimental

MethodsMendel hand-pollinated flowers using a paintbrush

He could snip the stamens to prevent self-pollinationCovered each flower with a cloth bag

He traced traits through the several generations

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How Mendel BeganMendel produced pure strains by allowing the plants to self-pollinate for several generations copyright cmassengale

Page 22: [PPT]Mendel's genetics - Miss Lee's 7th Grade Science Classsequoyahscience.weebly.com/uploads/3/8/9/3/38939833/mend... · Web viewAuthor Cheryl Massengale Created Date 02/26/2000

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Eight Pea Plant TraitsSeed shape --- Round (R) or Wrinkled

(r)Seed Color ---- Yellow (Y) or  Green

(y)Pod Shape --- Smooth (S) or wrinkled

(s)Pod Color ---  Green (G) or Yellow (g)Seed Coat Color ---Gray (G) or White

(g)Flower position---Axial (A) or

Terminal (a)Plant Height --- Tall (T) or Short (t)Flower color --- Purple (P) or white

(p)

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Punnett SquareUsed to determine possible genetic outcomes for offspring

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Monohybrid Crosses

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Trait: Seed ShapeAlleles: R – Round r – WrinkledCross: Round seeds x Wrinkled

seedsRR x rr

P1 Monohybrid Cross

R

R

rr

Rr

RrRr

Rr

Genotype: RrPhenotype: RoundGenotypicRatio: All alikePhenotypicRatio: All alike

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P1 Monohybrid Cross Review

Homozygous dominant x Homozygous recessive

Offspring all Heterozygous (hybrids)

Offspring called F1 generation Genotypic & Phenotypic ratio

is ALL ALIKE

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Trait: Seed ShapeAlleles: R – Round r – WrinkledCross: Round seeds x Round seeds

Rr x Rr

F1 Monohybrid Cross

R

r

rR

RR

rrRr

Rr

Genotype: RR, Rr, rrPhenotype: Round & wrinkledG.Ratio: 1:2:1P.Ratio: 3:1

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F1 Monohybrid Cross Review

Heterozygous x heterozygous Offspring:

25% Homozygous dominant RR50% Heterozygous Rr25% Homozygous Recessive rr

Offspring called F2 generation Genotypic ratio is 1:2:1 Phenotypic Ratio is 3:1

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What Do the Peas Look Like?

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…And Now the Test CrossMendel then crossed a pure &

a hybrid from his F2 generation

This is known as an F2 or test cross

There are two possible testcrosses:Homozygous dominant x HybridHomozygous recessive x Hybrid

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Trait: Seed ShapeAlleles: R – Round r – WrinkledCross: Round seeds x Round seeds

RR x Rr

F2 Monohybrid Cross (1st)

R

R

rR

RR

RrRR

Rr

Genotype: RR, RrPhenotype: RoundGenotypicRatio: 1:1PhenotypicRatio: All alikecopyright cmassengale

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Trait: Seed ShapeAlleles: R – Round r – WrinkledCross: Wrinkled seeds x Round seeds

rr x Rr

F2 Monohybrid Cross (2nd)

r

r

rR

Rr

rrRr

rr

Genotype: Rr, rrPhenotype: Round & WrinkledG. Ratio: 1:1P.Ratio: 1:1

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F2 Monohybrid Cross Review

Homozygous x heterozygous(hybrid)

Offspring:50% Homozygous RR or rr50% Heterozygous Rr

Phenotypic Ratio is 1:1 Called Test Cross because the

offspring have SAME genotype as parents

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Practice Your Crosses

Work the P1, F1, and both F2 Crosses for each of the other

Seven Pea Plant Traits

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Mendel’s Laws

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Results of Monohybrid Crosses

Inheritable factors or genes are responsible for all heritable characteristics

Phenotype is based on Genotype

Each trait is based on two genes, one from the mother and the other from the father

True-breeding individuals are homozygous ( both alleles) are the samecopyright cmassengale

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Law of Dominance In a cross of parents that are pure for contrasting traits, only one form of the trait will appear in the next generation.All the offspring will be heterozygous and express only the dominant trait.RR x rr yields all Rr (round seeds)

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Law of Dominance

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Law of SegregationDuring the formation of

gametes (eggs or sperm), the two alleles responsible for a trait separate from each other.

Alleles for a trait are then "recombined" at fertilization, producing the genotype for the traits of the offspring.

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Applying the Law of Segregation

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Law of Independent Assortment

Alleles for different traits are distributed to sex cells (& offspring) independently of one another.

This law can be illustrated using dihybrid crosses.

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Dihybrid Cross

RRYY

RRYy

RrYY

RrYy

RRYy

RRyy

RrYy

Rryy

RrYY

RrYy

rrYY

rrYy

RrYy

Rryy

rrYy

rryy

Round/Yellow: 9

Round/green: 3

wrinkled/Yellow: 3

wrinkled/green: 19:3:3:1 phenotypic ratio

RY Ry rY ry

RY

Ry

rY

ry

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Dihybrid Cross

Round/Yellow: 9Round/green: 3wrinkled/Yellow: 3wrinkled/green: 1

9:3:3:1

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Sex-linked Traits

Sex Chromosomes

XX chromosome - female Xy chromosome - male

fruit flyeye color

Example: Eye color in fruit flies

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Female Carriers

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Genetic Practice Problems

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Breed the P1 generation

tall (TT) x dwarf (tt) pea plants

T

T

t t

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Solution:

T

T

t t

Tt

Tt

Tt

Tt All Tt = tall(heterozygous tall)

produces theF1 generation

tall (TT) vs. dwarf (tt) pea plants

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Breed the F1 generation

tall (Tt) vs. tall (Tt) pea plants

T

t

T t

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Solution:

TT

Tt

Tt

tt

T

t

T tproduces theF2 generation1/4 (25%) = TT1/2 (50%) = Tt1/4 (25%) = tt1:2:1 genotype 3:1 phenotype

tall (Tt) x tall (Tt) pea plants

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