a FoodState Eventa FoodState Event

Launch of the Practitioners

Range Dr Leslie Pleass

Launch of the Practitioners

Range Dr Leslie Pleass

“Insurance claims for :Stress,

Depression and Job Burnout

Now the U.S.A’s fastest growing disability category”

FEBRUARY 12, 2007

STRESS

Rockefeller University

Dr. Bruce McEwen, Neuro-Endocrinologist

“We’re learning that post traumatic stress disorder, burnout, chronic fatigue syndrome

and fibromyalgia are related in some ways to stress.”

STRESS

University of California, San Francisco white blood cells women with children with chronic disorders eg; autism, cerebral palsy etc. Premature ageing - Telomeres, caps protect unraveling at ends of chromosome

pairs, Like plastic wrappers at end of shoelaces. Caps shorten each time cell divides

Young cells have long telomeres, old cells eventually shrink, stop dividing and die.

Stressed out Mothers had significantly shorter telomeres. 9 to 17 times older than their chronological age

Burn-OUT Causes: Body: Lack of sleep Reliant on stimulants Exercise Injuries Birth Pregnancy

Mind: Lifestyle Habits Addiction Economics Obsessions

Spirit: Death Divorce Isolation Insecurity

HPA AXIS(Hypothalamus, pituitary, adrenal)

Cortisol – high and prolonged in blood stream

Body: Thyroid Blood Sugars Bone Density Muscle Spasm Immune Inflammation Blood Pressure Abdominal fat – heart attacks, strokes

Mind: Cognition

Spirit: Adrenal exhaustion = “burn out”

B-group (4.32mg) - Folic acid (.05mg) - Pantothenic acid (5mg) - Adrenals

Vit. C (12.5mg) - Tyrosine (100mg) - Dopamine, noreadrenaline, thyroid

Stress management

Protects nerve cells

Anxiety, Stress, Fatigue, Moodiness, Restlessness, Insomnia and Irritability

Adaptogen, stress, prevents adrenal burnout

Restrained production of cortisol and anti-inflammatory

Rhodiola Rosea (50mg) - Eleutherococcus senticosus (100mg) Gotu Kola (25mg) -Avena Sativa (50mg) - Licorice root (124mg) - Reishi mushroom (25mg) - Cordyceps sinesis (25mg) -

Depression, chronic fatigue

Sedative, nerves, anxiety, apprehension hypertensionTension, nervous, stress.

Nervous symptoms, insomnia, stress, anxiety

Mood & spirit lifting

Medicinal mushrooms increase stamina, energy levels, and endurance.

• Aids the body in adapting to various stresses • Promotes vitality, immunity, and overall feeling of well-being• Includes adaptogens that are known for their stress protection properties as well as improving: energy, promoting restful sleep, and enhancing mental clarity and perception.• Promotes balance and support of the endocrine system

THE SECRET OF HAPPINESSHappiness Least HappyMarriage Divorce, Separation

WidowedExtra-marital affairs

Extroverts Introverts

Challenging Work Non challenging work

Church, Belief Non-BeliefIntense mystical experience

Team Sport Being an ”Island”, isolating oneself

Photographic souvenirs', old keepsakes

Watching Soapies Watching T VBeing very poorGoing on shopping sprees

Prof. Michael Argyl, Oxford University (11 years research) 1998

Source: DeMaeyer, EM, Dallman P, Gurney JM, Hallberg L, Sood SK, & Srikantia SG (1989). Preventing and controlling iron deficiency Anaemia through primary health care: a guide for health administrators and programme managers, pp 5-58 WHO Geneva

50% 50%55% 60%

25%

1. Iron deficiency - nutritional, loss of blood

2. Pernicious anaemia - Vitamin B12 deficiency

3. Megaloblastic anaemia - Lack of folic acid & B12

Abnormally low amount of red blood cells.

4. Sickle cell anemia - genetic African , Mediterranean, Middle Eastern descent .on Hemoglobin molecules tend to clump together, making red blood cells sticky, stiff, fragile, forming into a curved, sickle shape

Thalassemia major Thalassemia minor Mediterranean origin, Chinese, other Asians,

and blacks

Low haemoglobin productionExcessive destruction of red blood

cells

Anaemia by three months/eighteen months, pale, sleep poorly, no appetite, may vomit after feedings. If untreated, fatal between one and eight years of age.

Paleness Headaches Fatigue Shortness of breath Jaundice Spleen enlargement

Folic acid (a vitamin that your body needs to produce new red blood cells).

Joint pain Fatigue Lack of energy Weight loss Generalized darkening of skin colour (often referred to as bronzing) Abdominal pain Loss of sexual desire Testicular atrophy Loss of body hair Weakness Heart problems Symptoms related to the onset of diabetes

HaemochromatosisToo much iron builds up in the liver.

This leads to liver enlargement

Primary haemochromatosis is the most common genetic disorder in the United States, affecting an estimated 1out of every 200 to 300 Americans.

Body: Anaemic Pale appearance Pale conjunctiva Smooth tongue Fatigue Immune Spoon shaped brittle nails Shortness of breath

Cold extremitiesRapid fluttering heartbeatCraving ice, dirt, clay (pica)Corners of mouth crackHypochlorrhydria,

Helicobacter pylori

Mind: Irritable, compulsive

Spirit: Iron lady

Iron 5 mgMolybdenum 10 µg

FoodState®Iron & Molybdenum Complex

Vitamin B12 30 μg

Vitamin B6 10 mg

Vitamin C 30 mg

Folic acid 400 μg

Copper 1 mgIron 25 mg

Molybdenum 30 μg

Vitamin E 50 iu

Minerals are notoriously difficult to absorb. FoodState’s unbeatable Iron is totally absorbed

due to its unique delivery system, It’s also non-toxic and easily stored and has no side effects.

Iron Man

HAEMOSTATE

Side-effects from taking synthetic Iron

NauseaHeartburn

An upset stomach Constipation

DiarrhoeaStools black

Vomiting

FoodState versus Chelated iron

Blood and liver

At least 50% more bioavailability

Bioavailability Studies

77141400

pHpH

11 22 33 44 55 66 88 99 1010 1111 1212 1313

10 00010 000 1 0001 000 100100 10 10 10 10 100100 1 0001 000 10 00010 000

AcidosisAcidosis AlkalosisAlkalosis

7,47,4

pH-State

All ingested substances and all situations (physical, emotional or mental) that affect the body, leave either an alkaline or acid

ash residue in the urine

pH-StatepH = potential HydrogenA measurement of

Hydroxyl (oH-) ions which are negative and alkaline forming

related to Hydrogen (H+) ions that are positive and acid

forming

pH is the measurement of electrical resistance between negative and positive ions in the body

(electro-chemical reactions)

pH-StateAn alkaline forming reaction refers to any

chemical alteration in the body that produces an increased ability to energise the system and leaves an alkaline residue in the body.

An acid forming reaction refers to any chemical alteration in the body that produces a decreased ability to energise the system and leaves an acid residue in the urine.

pH-StateALKALINE FORMING MINERALS (ACID

BINDING)

Calcium, Magnesium, Sodium, Potassium, Iron & Manganese

ACID FORMING MINERALS (ALKALINE BINDING)

Sulphur, Chlorine, Iodine Bromine, Fluorine, Copper, Silicon

pH-StateDuring Sleep Body electricity: pulses at 0.5 and 2.5 times per second

Our body switches to alkaline phase CNS is electromagnetically negative (producing south seeking magnetic field) Our electrons spin in counter-clockwise direction Stimulates production of anabolic hormones (Melatonin & Growth hormone)

On Awakening Consciousness emerges 22 cycles per second with low amplitude The more alkalinity, the greater the amplitude of electricity

pH-StateAlkaline forming foods

Most fruits & vegetables Granola cereal Almonds, chestnut, coconut Alfalfa, radish Avocado, olive, soy, sunflower Brown rice, sugar, honey Fruit juices, vegetable juices, herbal teas Garlic, salt, tomato sauce, vinegar (apple

cider), yeast

pH-StateAcid forming foods

Most meats Plums, prunes Barley, brown rice, oats, rye, wheat, white rice Broad beans, kidney beans, lentils Brans, refined breads Brazil, cashew, macadamia, peanuts, walnuts Pumpkin, sunflower, wheat germ Cheese (or neutral) Cream, eggs, milk Artificial sweeteners Honey (processed, pasteurized)Wine, beer, coffee White processed vinegar

pH-StateALKALINE electromagnetic fields Encourages maximum phosphorylation Alkaline blood increases protein synthesis Alkaline tissues and blood convert acids and free

radicals to water & oxygen Create antibiotic blood interface with dysbiotic

pleomorphic organisms Alkaline blood & tissues neutralize toxins,

restore and maintain vitality

pH-StateENERGY is released when anions & cations

merge Anions migrate toward the sun (e.g. fruit &

vegetables containing calcium [leafy greens] potassium, sodium & magnesium)

Cations migrate toward the centre of the earth (denatured foods, calcium from inorganic sources) stomach requires cationic energy (acidity) for optimal efficiency

pH-StateRx pH-StateSupplement to help maintain the body’s acid-base balanceDaily dose =   approx. 3 g 

        Active /daily dose

 FoodState blend:

Calcium 400 mg

Magnesium 167 mg

Potassium 12.8 mg

Phosphorus 30 mg

Potassium bicarbonate 200 mg

Potassium citrate 250 mg

Alfalfa 500 mg

Lactitol 1000 mg

VasoStateTypes of Cholesterol1. Low Density Lipoprotein (LDL)

Harmful form of cholesterol

Influenced by diet

2. High Density Lipoprotein (HDL) Helpful Cholesterol – transports cholesterol to the liver

Influenced by exercise

3. Triglycerides Fats carried through the bloodstream

Stored in fat tissue

Factors influencing Cholesterol levels

1. Heredity (familial hypercholesterolaemia)

2. Diet – Saturated & trans fatty acids Contain cholesterol – meat, poultry, seafood, dairy products

Contains no cholesterol – fruits, vegetables, vegetable oils, grains, cereals, nuts, seeds

3. Weight – Excess weight tends to increase LDL level. Weight loss tends to reduce Triglycerides and raise HDL

4. Physical activity/exercise – helps raise HDL

VasoState

VasoStateFactors influencing Cholesterol levels5. Age & sex

Blood cholesterol rises until about 60 or 65 years of age

After 50 years of age, women often have higher levels of cholesterol

6. Alcohol Increases HDL – does not lower LDL Too much harms. Limited intake reduces

risk of heart attack.

7. Stress Raises cholesterol levels (maybe because of

consolation eating)

VasoStateElevated CholesterolFACT

Elevated cholesterol is associated with atherosclerosis & cardiovascular disease (CVD)

QUESTION

Is it only cholesterol that causes atherosclerosis or are there other predisposing factors?

Influences & risk factors associated with CVD1. Low ascorbate levels

Cause lesions & predispose to plaquing

2. Excessive Homocysteine

Caused by deficiency of B6 , B12 & Folic acid during methylation process

VasoStateInfluences & risk factors associated

with CVD3. Excessive free radical formation

Caused by environmental pollution and smoking

4. Dehydration

Causes thicker, acid blood

Heart Disease & Vitamin CHeart Disease & Vitamin C Arteries are commonly depleted of Vitamin C, even in individuals

who appear healthy & well-nourished Even when cholesterol is largely eliminated from diet, Vitamin C

deficiency can cause cholesterol accumulation in heart arteries

Large daily doses of Vitamin C and comparable doses of lysine reduce anginal chest pain

Multiple studies show that diabetics have depressed, scurvy-like plasma levels of Vitamin C

Studies show that heart attacks occur more often in winter months, corresponding to decreased levels of Vitamin C due to

seasonal variations A clear protocol for preventing and reversing arterial blockages is

available and has been borne out via many studies

Thomas E. Levy MD, JD. Stop Americas #1 Killer

VasoStateNiacin (Vit B3)

1. Inhibits free fatty acid release from adipose tissue

2. Inhibits cyclic AMP accumulation which controls activity of triglyceride, lipase & hence lipolysis

3. Decreases rate of liver synthesis of LDL & VLDL

4. Produces vasodilation of cutaneous blood vessels of face, neck & chest

VasoStatePolicosonol Is a mixture of waxy alcohols derived from

certain plants including sugar cane & wheat germ oil

Inhibits liver cholesterol synthesis

Increases degradation of LDL

Decreases collagen induced platelet aggregation (equal to 100mg of aspirin per day)

Alpha-Linolenic C 18:3

C 18: 4

Linoleic C 18:2

Gamma-linolenic

C18:3

Dihomogamma-

linolenic C 20:3

n - 6 Enzyme n - 3

6-Desaturase

Elongase

5-DesaturaseArachidonic

C 20 : 4

C 20 : 4

Prostaglandins

(1 series)

Prostaglandins(3 series)

Thromboxanes

Leukotrienes

(4-series)

Prostaglandins(2 series)

Thromboxanes

Leukotrienes

(5-series)Elongase

4-Desaturase

Eicosapentaenoic C 20:5

C 22:5

Docosahexaenoic C 22:6

Effect Of FoodState® Vitamin CPlasma Cholesterol - LDL+VLDL - Triglyceride

(After One Month)

100

100

100

77

66

40

TotalCholesterol

LDL+VLDL

Triglyceride

Control FoodState

Journal of Agriculture & Food Chemistry, Vinson et al

FoodState® Vitamin C

Decreased the amount of triglycerides by 16% Increased the lag time by 29%

Triglycerides are indicators of Heart Disease

Vinson, J.A. and Jang, J.; J. Med. Food, 2001, 4, 187-192.

FoodState® & Isolated USP CALCIUM% Change in human diastolic blood pressure

-15

-10

-5

0

5

1 2 3 4 5 6 7 8

NUMBER OF WEEKS

% C

HA

NG

E

FOODSTATE CALCIUM GLUCONATE PLACEBO YEAST

VasoStateResearch

Policosinol

A. American Heart Journal (2002) Gourni-Bert et al

1. Doses of 10mg to 20 mg per day lowered total cholesterol by 17% - 21% Lowered LDL by 21% to 29% Raised HDL by 8% to 15%

2. Doses of 20 mg per day are safe and well tolerated >3yr studies indicate

VasoStateResearch

B. Int. J. Clin. Pharmacology Res (1999) Crespo et al.(53 patients) A randomized double

blind studyDoses of 10mg Policosonol20 mg Lovastatin

Results :Policosonol :

Lowered LDL by 20,4% Lowered total cholesterol by 14,2%

Lowered ratio LDL : HDL by 23,7%Raised levels of HDL – 7,5%

Lovastatin :Lowered LDL BY 16,8%Lowered total cholesterol by 14,0%Lowered ratio LDL : HDL by 14,9%Adverse reactions more frequent

VasoStateResearchC. Chemistry and Laboratory Medicine (2007)

Yagura C, et al. Study of 132 Japanese adults (mean age 21,4yrs)

Results :“Serum folate levels were significantly inversely associated with plasma

total homocysteine levels”

D. Lancet (2007) Yokohama M et al., trial conducted on 18645 patients. Mean age 61 yrs (69% women) Cholesterol levels 7,1 mmol/lFollow up over 4.6 yearstested 1 EPA + Statin

2 Statin

Results :EPA gpe – 19% reduction in major coronary events (10% in control

gpe) (sudden cardiac death, fatal and non-fatal myocardial infarction). Both gpes reduced LDL by 25%

VasoStateResearchE. BMJ (1995)

730 men and women 20 year follow up study Results :

“Mortality from stroke was highest with the lowest Vit C status (dietary intake or plasma concentration)”

VasoStateRx VasoStateSupplement to help with high cholesterol and homocysteine levels

Active  per two tablets :

FoodState: Essential fatty acids:    

Vitamin B3 (Niacin) 100 mg Linolenic acid (Omega 3) 50 mg

Vitamin B6 10 mg Oleic acid (Omega 9) 30 mg

Vitamin B12 50 μg Linoleic acid (Omega 6) 19 mg

Folic acid 200 μg Palmitic acid 19 mg

Vitamin C 200 mg Stearic acid 13 mg

Vitamin E 50 iu Other 5 mg

Magnesium 15 mg Trimethyl Glycine (Betaine) 250 mg

Ginger 200   mg

Betasitosterol 60 mg

Policosonol 10 mg

Dose : 2 – 4 tablets daily

Disorders of blood sugar Disorders of blood sugar imbalances:imbalances:

Hypoglycaemia/HyperglycaemiaHypoglycaemia/Hyperglycaemia

Metabolic Syndrome Metabolic Syndrome

DiabetesDiabetes

Signs of Metabolic SyndromeSigns of Metabolic Syndrome

TriglyceridesTriglycerides

HDLHDL

BP (> 130/85)BP (> 130/85)

GlucoseGlucose

Abdominal obesityAbdominal obesity (M) (F)(M) (F)

>102cms >88cms>102cms >88cms

Signs of Metabolic SyndromeSigns of Metabolic Syndrome Yo-yo weightYo-yo weight

Gall bladder (forty, fat, fair)Gall bladder (forty, fat, fair)

Dark skin Dark skin

Unwanted facial hairUnwanted facial hair

Skin tags & ageing acneSkin tags & ageing acne

DepressionDepression

Signs of Metabolic SyndromeSigns of Metabolic Syndrome SnoringSnoring

Gout Gout

Low grade inflammationLow grade inflammation (Fibromyalgia) (Fibromyalgia)

Colon PolypsColon Polyps

Polycystic ovariesPolycystic ovaries

Liver involvementLiver involvement

Metabolic Syndrome Metabolic Syndrome Other symptoms :Other symptoms : Stiffening of jointsStiffening of joints

Connective tissue degeneration Connective tissue degeneration (wrinkles)(wrinkles)

AllergiesAllergies

Shrinkage of tissues requiring high Shrinkage of tissues requiring high amounts of glucose (muscles)amounts of glucose (muscles)

Metabolic SyndromeMetabolic SyndromePossible causes :Possible causes :

1)1) We eat 20 x more refinedWe eat 20 x more refined carbohydrates carbohydrates than our ancestorsthan our ancestors

2)2) We eat 10-20 x less vitamins and mineralsWe eat 10-20 x less vitamins and minerals

3)3) We consume much more sugarWe consume much more sugar1840 – 4 teaspoons daily1840 – 4 teaspoons daily 1990 – 29 teaspoons daily1990 – 29 teaspoons daily

- processed foods & beverages - processed foods & beverages

Overweight Overweight - the consequences- the consequences

19% of all heart disorders19% of all heart disorders

57% of diabetes conditions57% of diabetes conditions

30% of gallbladder diseases30% of gallbladder diseases

2,3% of cancer conditions2,3% of cancer conditions

In SA at least 32% of all adults are In SA at least 32% of all adults are overweightoverweight

Weighty IssuesWeighty Issues

25% of our children between 12-18 25% of our children between 12-18 years are overweight or obese years are overweight or obese

20% of children20% of childrenunder 6 yearsunder 6 years are are overweightoverweight

10% of children 10% of children under 2 years are overweightunder 2 years are overweight

Glucose & InsulinGlucose & InsulinIncreased dietary protein modifies Glucose & Increased dietary protein modifies Glucose & Insulin homeostasis in Adult Women during Insulin homeostasis in Adult Women during weight lossweight loss 24 x 45 – 56 year old women >15% above 24 x 45 – 56 year old women >15% above

ideal body weight (University of Illinois)ideal body weight (University of Illinois) 2 Groups2 Groups

30% Protein 40% carbohydrate 30% fat30% Protein 40% carbohydrate 30% fat 15% Protein 55% carbohydrate 30% fat15% Protein 55% carbohydrate 30% fat

11 week trial11 week trial Donald K. Layman et al Donald K. Layman et al

Division of Nutrition ScienceDivision of Nutrition ScienceUniversity of Illinois (2002)University of Illinois (2002)

Plasma Glucose concentrations in Plasma Glucose concentrations in fasting womenfasting women

DiabetesDiabetes

Type 1 :Type 1 : Insulin dependant diabetes Insulin dependant diabetes (10% of cases)(10% of cases)

Type 2 :Type 2 : Maturity onset diabetes (non- Maturity onset diabetes (non-insulin dependant diabetes)insulin dependant diabetes)(90% of cases)(90% of cases)

Both have elevated blood sugar levels due to Both have elevated blood sugar levels due to inefficiencies of insulin metabolisminefficiencies of insulin metabolism

MRC StatsMRC Stats 6,000,000 have hypertension6,000,000 have hypertension

4,000,000 have diabetes4,000,000 have diabetes

7,000,000 are smokers7,000,000 are smokers

4,000,000 have elevated 4,000,000 have elevated cholesterolcholesterol

5,000,000 have HIV5,000,000 have HIV

Symptoms of DiabetesSymptoms of Diabetes Frequent urinationFrequent urination Excessive thirstExcessive thirst Unexplained weight lossUnexplained weight loss Extreme hungerExtreme hunger Sudden vision changesSudden vision changes Tingling or numbness in hands or feetTingling or numbness in hands or feet Feeling tired much of the timeFeeling tired much of the time Extremely dry skinExtremely dry skin Sores that are slow to healSores that are slow to heal More infections than usualMore infections than usual

DiabetesDiabetesClinical conditions :Clinical conditions :

Heart & blood vessel damageHeart & blood vessel damage Eye damage & diabetic retinopathyEye damage & diabetic retinopathy Thrush infectionsThrush infections Dry, itchy skin with shiny legs and sores Dry, itchy skin with shiny legs and sores

that don’t heal (gangrene)that don’t heal (gangrene) ImpotenceImpotence Kidney damage (nephropathy)Kidney damage (nephropathy) Mental function & dementiaMental function & dementia

Diabetes Type IIDiabetes Type II

Major risk factors :Major risk factors : OverweightOverweight Family historyFamily history Ethnicity : 2 – 6 x higher among blacksEthnicity : 2 – 6 x higher among blacks Lack of exerciseLack of exercise >45 years of age>45 years of age Poor dietPoor diet SmokingSmoking

Diabetes Type IIDiabetes Type IITreatment :Treatment :

1)1) DietDietLimit fats, protein, refined Limit fats, protein, refined

carbohydrates. Eat plenty of fresh carbohydrates. Eat plenty of fresh vegetables & fibrevegetables & fibre

2)2) Reduce overweight conditionReduce overweight condition

3)3) Exercise (aerobic)Exercise (aerobic)Improves insulin sensitivityImproves insulin sensitivity

4)4) Wise supplementationWise supplementation-- GTF Chromium, GTF Chromium,

Vanadium, Vanadium, MagnesiumMagnesium

Glycaemic IndexGlycaemic Index RankingRanking

Immediate effect on blood Immediate effect on blood glucoseglucose

Glycaemic IndexGlycaemic Index

Chromium GTFChromium GTF Glucose tolerance factor (GTF) is 50x Glucose tolerance factor (GTF) is 50x

more effective than other forms of more effective than other forms of chromium and 20 times better chromium and 20 times better

absorbedabsorbed

Chromium is very poorly absorbed from Chromium is very poorly absorbed from food (3-10%)food (3-10%)

Chromium GTF improves insulin activityChromium GTF improves insulin activity

Safe range of intake is between 50 – 200 Safe range of intake is between 50 – 200 micrograms per daymicrograms per day

Chromium GTFChromium GTF

Functions :Functions : Stimulates protein synthesisStimulates protein synthesis

Stimulates production of essential nerve Stimulates production of essential nerve substancessubstances

Increases resistance to infectionIncreases resistance to infection

Suppresses hunger symptoms through brain Suppresses hunger symptoms through brain “satiety centre”“satiety centre”

Chromium GTFChromium GTFTherapeutic usesTherapeutic uses HypoglycaemiaHypoglycaemia

Metabolic Syndrome Metabolic Syndrome

Maturity onset diabetesMaturity onset diabetes

Some child & adult diabetesSome child & adult diabetes

Reducing high blood cholesterolReducing high blood cholesterol

Diabetes and pregnancyDiabetes and pregnancy

ChromiumChromiumComparative effect of various forms of Comparative effect of various forms of Chromium on serum glucose (Human Chromium on serum glucose (Human Study)Study)

Study conducted at Department of Study conducted at Department of Chemistry, Scranton UniversityChemistry, Scranton University

TestedTested 1)1) Inorganic ChromiumInorganic Chromium2)2) Brewers YeastBrewers Yeast3)3) FoodState ChromiumFoodState Chromium

Dose was 100Dose was 100µg of Chromiumµg of Chromium

ChromiumChromium

12 hour overnight fast12 hour overnight fast

-- then base line serum glucose levelsthen base line serum glucose levels

-- then tests after 1, 2 and 3 hours then tests after 1, 2 and 3 hours (highest results after 1 to 2 hours)(highest results after 1 to 2 hours)

Published in Nutrition Reports Published in Nutrition Reports InternationalInternational

Maximum % in decrease in serum Maximum % in decrease in serum GlucoseGlucose

Subject Inorganic

Chromium

Brewer’s

Yeast

FoodState

Chromium 1 3.6 0.6 28.0

2 13.6 10.8 22.7

3 7.4 12.9 17.4

4 4.5 4.8 14.8

5 1.0 1.4 12.5

6 5.3 8.0 9.6

7 6.6 1.2 12.3

Mean S.D. 6.0% 5.7% 16.8%

ChromiumChromiumNutrient Availability :Nutrient Availability :

Chemical and Biological AspectsChemical and Biological Aspects

FoodStateFoodState®® Vitamins and minerals are more Vitamins and minerals are more slowly absorbed in animals and man; are slowly absorbed in animals and man; are more bioavailable; and are therefore the more bioavailable; and are therefore the preferred form for supplementation. preferred form for supplementation. (FoodState(FoodState®® Chromium GTF bioavailability Chromium GTF bioavailability 3,56 x higher than inorganic chromium)3,56 x higher than inorganic chromium)

D.A.T.D.A.T. Southgate et alSouthgate et al

Royal Society of ChemistryRoyal Society of Chemistry

MagnesiumMagnesium Co-factor in processing energy Co-factor in processing energy

productionproduction Depleted with high sugar intakeDepleted with high sugar intake Co-factor in reducing hyperactivity in Co-factor in reducing hyperactivity in

childrenchildren Deficiency symptom is low blood Deficiency symptom is low blood

sugarsugar Used therapeutically for Used therapeutically for

hypoglycaemiahypoglycaemia

VanadiumVanadiumDeficiencies :Deficiencies : Reduction of red blood cells – anemiaReduction of red blood cells – anemia

Increased blood fat levelsIncreased blood fat levels

Increased cholesterol levelsIncreased cholesterol levels

Functions :Functions : Fat metabolismFat metabolism Minimises craving for sugarMinimises craving for sugar Assists in digestive functionAssists in digestive function

Alpha-Linolenic C 18:3

C 18: 4

Linoleic C 18:2

Gamma-linolenic

C18:3

Dihomogamma-

linolenic C 20:3

n - 6 Enzyme n - 3

6-Desaturase

Elongase

5-DesaturaseArachidonic

C 20 : 4

C 20 : 4

Prostaglandins

(1 series)

Prostaglandins(3 series)

Thromboxanes

Leukotrienes

(4-series)

Prostaglandins(2 series)

Thromboxanes

Leukotrienes

(5-series)Elongase

4-Desaturase

Eicosapentaenoic C 20:5

C 22:5

Docosahexaenoic C 22:6

Signs of Fatty Acid ImbalanceSigns of Fatty Acid ImbalanceDry Skin Alligator Skin “Chicken Skin” on

back of arms

Dandruff Lowered immunity Dry eyes

Frequent urination

Fatigue Poor wound healing

Irritability Dry, unmanageable hair

Frequent infections

Attention deficit Hyperactivity Learning problems

Soft nails Brittle, easily frayed nails

Patches of pale skin on cheeks

Allergies Excessive thirst Cracked skin on heels or fingertips

From the book “Smart Fats”From the book “Smart Fats”

Essential Fatty Acids

OMEGA 3OMEGA 3

Alpha-Lin. Acid

(parent EFA)

DELTA 6

DesaturaseEPA PG3

Prostacyclin PG3

(Derived EFA)

Essential Fatty Acids

* Saturated fats

* Refined Carbohydrates* Radiation

*Zinc Deficiency* Cholesterol

* Alcohol * Insulin Deficiency

* Ageing * Viral infections

*Cystic Fibrosis* B6 Deficiency

* Cirrhosis* “Trans” Fatty Acids

DELTA-6 DESATURASEDELTA-6 DESATURASE

Linoleic Acid

Alpha-Lin.

Acid

Bitter MelonBitter Melon(MOMORDICA CHARANTIA)(MOMORDICA CHARANTIA)

Best action – fruit & seeds Have hypoglycaemic effect in humans &

animals Contains insulin – like polypeptide called

Polypeptide P (p-insulin)Has similar pharmalogic effects to bovine insulin(action between 1 hour and 4 hours)

Slows progression of microalbuminurea and diabetic nephropathy

Flavonoids help reduce cholesterol(Natural Medicines Comprehensive Database)

Cinnamon ExtractCinnamon Extract Best action – bark Active ingredient for sugar control is METHYLHYDROXYCHALCONE POLYMER (MHCP) Seems to mimic the activity of insulin, stimulating glucose metabolism Appears to work synergistically with insulin

by improving insulin signalling pathways

(Natural Medicines Comprehensive Database)

FenugreekFenugreek(Trigonella Foenugraecum)(Trigonella Foenugraecum)

Best action – bark Active ingredient is 4-hydroxyisoleucine Stimulates insulin production in presence of

moderate to high glucose concentrations Contains Galactomannin which helps normalize blood sugar levels

(Natural Medicines Comprehensive Database)

GymnemaGymnema(Gymnema Sylvestre)(Gymnema Sylvestre)

Best action – bark Gymnemic acids seems to :

reduce intestinal absorption of glucose may stimulate pancreatic beta cell growth

Can increase serum C-peptide levels, suggesting an increase in endogenous insulin secretion

(Natural Medicines Comprehensive Database)

GlucoState GlucoState

Daily dose = 2 tablets

 Active qty per tablet

Foodstate blend:-

Magnesium 15 mg

Chromium GTF 75 µg

Vanadium 25 µg

Omega 3 powder 100 mg

Fenugreek extract 45 mg

Gymnema sylvestre extract 50 mg

Cinnamon extract 50 mg

Bitter melon extract 50 mg

Supplement to help balance high blood sugar levels

FloraState

FloraState

FloraState

The ColonThe Colon(Large Intestine)(Large Intestine)

1.1. Contains between 400 to 500 Contains between 400 to 500 species of species of bacteriabacteria --

some can cause illness, others can some can cause illness, others can promote healthpromote health

2.2. 2 major health promoting bacteria are 2 major health promoting bacteria are known as PROBIOTICSknown as PROBIOTICS-- LactobacilliLactobacilli-- BifidobacteriaBifidobacteria

(some of these are found in live yoghurt but are unstable)(some of these are found in live yoghurt but are unstable)

Probiotics- Means “For Life” as contrasted with….

Antibiotics

- “Against life”

History

- It is said that Abraham owed his long life to the consumption of sour milk – Gen 18vs8

- Roman historian Plinius recommended fermented milk products for treating gastroenteritis

- Early researchers claimed that yoghurt increased longevity, reduced diarrhoea and was abundant in the gut of breast fed infants.

FloraState

Probiotics- These are live strains of good bacteria which help our digestive system work efficiently

- These include Lactobacillus and Bifidobacteria

Prebiotics- These are nutrients and components of food upon which our gut bacteria feed

- These include inulin and fructo-oligosaccharides (found in artichokes, chickory root, leeks, onions & garlic)

Synbiotics- These are where probiotics and prebiotics are used in combination.

- This improves the survival of the probiotic organism because its specific substrate is available

FloraState

When do we need probiotics?

When we take antibiotics

When we have diarrhoea

To help atopic eczema

To help treat candidiasis

To reduce allergies

To improve immunity

FloraState

Candida albicans “Yeast” infection

Candida albicansPeople at risk of Candida albicans infections:

Diabetics People taking antibiotics Infants The elderly Immunocompromised subjects

Areas which are affected: Oral cavity Skin Nails Hair Vagina („yeast infection“) etc.

Athletes and immunity

Strenuous exercise compromises immunity and increases viral and respiratory infections

Health issues in athletesHigh incidence of respiratory infectionsPhysical and mental stressFatigue, impaired performanceFatigue has been associated with viral

infections (Epstein Barr Virus) and increased shedding of EBV

Symptoms of Poor EliminationSymptoms of Poor Elimination ConstipationConstipation Spastic ColonSpastic Colon HeadachesHeadaches Abdominal BloatingAbdominal Bloating FatigueFatigue AllergiesAllergies Poor circulationPoor circulation Skin disorders (Acne, Eczema, Skin disorders (Acne, Eczema,

Psoriasis)Psoriasis) HalitosisHalitosis Coated tongueCoated tongue

Other Symptoms of Poor Other Symptoms of Poor EliminationElimination

Mucus in stoolsMucus in stools Liver sluggishness Liver sluggishness (Nausea)(Nausea) DepressionDepression BackacheBackache Sinus congestionSinus congestion Loss of concentrationLoss of concentration ParasitesParasites

Pathologies associated with Pathologies associated with Poor DigestionPoor Digestion

ConstipationConstipation Colitis Colitis DiarrhoeaDiarrhoea HaemorrhoidsHaemorrhoids CandidiasisCandidiasis Myalgic encephalomyelitisMyalgic encephalomyelitis Irritable Bowel Syndrome Irritable Bowel Syndrome

(IBS)(IBS)

Fibre TypesFibre Types1.1. Insoluble Fibre e.g. Bran Insoluble Fibre e.g. Bran

(normally wheat)(normally wheat)

2.2. Soluble Fibre e.g. Oats & Oat Soluble Fibre e.g. Oats & Oat BranBran

3.3. Prebiotic non-digestible fibre Prebiotic non-digestible fibre e.g. OLIGOSACCHARIDES : INULIN, e.g. OLIGOSACCHARIDES : INULIN, OLIGOFRUCTOSE, BETA-GLUCAN OLIGOFRUCTOSE, BETA-GLUCAN (found (found in Leeks, Onions, Bananas, Jerusalem Artichokes, in Leeks, Onions, Bananas, Jerusalem Artichokes, Chicory root, Oats)Chicory root, Oats)

PrebioticsPrebioticsPrebioticsPrebiotics

Good bacteria Good bacteria secretes enzymessecretes enzymes

Inhibit growth of Inhibit growth of disease causingdisease causing bacteriabacteria

Balance of flora tips in Balance of flora tips in healthy direction (crowds healthy direction (crowds out disease causing out disease causing bacteria)bacteria)

Growth enhancer for probiotics Growth enhancer for probiotics (lactobacilli & bifidobacteria) (lactobacilli & bifidobacteria)

Break down prebiotics into Break down prebiotics into acetic and butyric acidacetic and butyric acid

Good bacteria secretes Good bacteria secretes antibodies to restrain antibodies to restrain unhealthy bugsunhealthy bugs

Probiotics thrive Probiotics thrive Gastric acidGastric acid Digestive enzymesDigestive enzymes Immune system Immune system

How prebiotics tilt the balance How prebiotics tilt the balance in favour of ‘good’ bacteriain favour of ‘good’ bacteria

Introducing prebiotics (shown as hexagonal long chains) Introducing prebiotics (shown as hexagonal long chains) provides food for the ‘good bugs’provides food for the ‘good bugs’

Probiotic cultures 3.5 x 109 cfu

Bifidobacterium breve  

Bifidobacterium bifidum  

Bifidobacterium longum  

Streptococcus thermophilus  

Lactobacillus acidophilus  

Lactococcus lactis  

Lactobacillus rhamnosus  

Lactobacillus casei  

Lactobacillus plantarum  

Fructo-oligosaccharides (FOS) 35mg

FloraState

a FoodState Eventa FoodState Event

Complementary / Alternative MedicineComplementary / Alternative Medicine

Conventional MedicineConventional Medicine

Integrative Medicine

Integrative Medicine