presentation
TRANSCRIPT
Early Childhood Caries:Early Childhood Caries:Do We Have Sufficient Evidence of Effective Do We Have Sufficient Evidence of Effective Interventions to Reverse National Trends?Interventions to Reverse National Trends?
Gary Rozier, DDS, MPH
USPHS Symposium Dental Category Day
Atlanta, GA
June 2, 2009
Surgeon General’s ReportSurgeon General’s Report on Oral Health, 2000on Oral Health, 2000
• Dental caries is the most common chronic disease of childhood, affecting about half of children by middle childhood, and over 80% by late adolescence.
• Research demonstrates that oral and dental diseases have a significant impact on children and families.
• Many Americans lack access to needed oral health care, including many infants and young children.
0
0.2
0.4
0.6
0.8
1
1.2
1.4
1.6
1.8
1971-74 1988-94 1999-04
%
Trends in Caries Experience byTrends in Caries Experience by Dentition Type, U.S., 1971 - 2004Dentition Type, U.S., 1971 - 2004
Permanent teeth,6-11 years of age
0
0.2
0.4
0.6
0.8
1
1.2
1.4
1.6
1.8
1971-74 1988-94 1999-04
%
Trends in Caries Experience byTrends in Caries Experience by Dentition Type, U.S., 1971 - 2004Dentition Type, U.S., 1971 - 2004
Permanent teeth,6-11 years of age
Primary teeth,2-5 years of age
……U.S. GAO report concluded, referring to the federal/state health program for poor people.
…about 6.5 million children enrolled in Medicaid had untreated tooth decay in 2005.
The GAO report was ordered after…Deamonte Driver, a 12-year-old boy…died last year in suburban Washington when an untreated infected tooth led to a brain infection.
http://www.cnn.com/2008/US/09/23/dentalcare.medicaid/ind
Millions of poor American children have untreated tooth decay, some of them because they cannot find a dentist willing to treat them, a federal report issued Tuesday said. Only 1 in 3 children in Medicaid received any dental care over a year time span...
ABC News- March 6, 2009ABC News- March 6, 2009
Brandon had an astounding 16 baby root canals completed at one visit--nearly every tooth in his mouth. "He comes walking out of that door…and he had blood dripping from his mouth. And all I could see was silver shining through.“ [Mother]
Hunter, another child who received the same treatment and was just starting pre-kindergarten, was teased by other children as a "metal mouth" and said "it just made me feel, like, bad." "I feel like they took my son's smile away." [Mother]
% parents reporting child dental problems or treatment affecting child or family “occasionally, often or very often” among parents of children with obvious caries experience (d2mfs>0)
Impact PercentChild overall impacts 35
Eating, drinking, talking, daycare 26
Pain 17
Sleeping, irritable 16
Smiling, talking 4
Parent overall impacts 45
Upset, guilty 36
Work, finances 23
Both child and parent impacts 58
ImpactsImpacts of Dental Diseaseof Dental Disease
ResponseResponse
• Growing concern over pediatric oral health
• States are experimenting with new models
• Physicians are being called upon to provide dental services– Surgeon General’s Report & Conference (2000)– ADA Future of Dentistry Report (2001)– AAP Policy Statements (2003, 2008)– Bright Futures Guidelines, 3rd Ed., 2008
“Maine has 2 DDS for every 2,300 people, compared to 1 MD for every 640. Nationally there is 1 DDS for every 1,600 people.”
“In Maine, training MDs in dentistry provides a dental safety net for the rural poor.”
March 3, 2009Short of Dentists, Maine Adds Teeth to Doctors’ Training
Ronald Smart who had not been to a dentist in 5 years, came to Fairfield clinic to have an infected tooth pulled; he has had 3 pulled there before, and likely Will have more.
AssumptionsAssumptions
• ECC is a serious public health problem
• Its burden can be reduced through prevention targeted to young children
• Virtually all infants & toddlers obtain care at medical offices and it is a logical place to provide preventive dental services
• Physicians know that ECC is a problem and they want to help prevent it
AssumptionsAssumptions
• Primary medical care providers need help to learn procedures and to implement them in their practices
• Evidence of effectiveness is limited and these Innovations should be evaluated for effectiveness
Aims of PresentationAims of Presentation
• Review evidence for prevention of ECC
• Review efforts in North Carolina and elsewhere to involve non-dental primary care clinicians in oral health promotion and dental disease prevention
• Discuss potential for model to reduce disparities in oral health
• Future directions
Caries Prevention MethodsCaries Prevention Methods
FoodFood
HostHost
BacteriaBacteria
Plague controlFluoride therapy
Sealants
Fluoride therapy
Antimicrobials
Anti-cariesVaccine
Diet Counseling
Multifactoral DiseaseMultifactoral Disease
.... a quick look
at preventive methods for
primary care setting.....
USPSTF Systematic ReviewUSPSTF Systematic Review1) How accurate is Primary Care Clinicians’
(PCC) screening in identifying children 0 to 5 years of age who:a) have dental caries requiring referral to a dentist?b) are at elevated risk of future dental caries?
2) How effective is PCC referral of children 0 to 5 years to dentists in terms of the proportion of referred children making a dental visit?
3) How effective is PCC prescription of supplemental fluoride in terms of:a) appropriateness of the supplementation decision?b) parental adherence to the dosage regimen?c) prevention of caries?
USPSTF Systematic ReviewUSPSTF Systematic Review4) How effective is PCC application of fluoride
in terms of : a) appropriateness of the application decision?b) achieving parental agreement for application?c) prevention of caries?
5) How effective is PCC counseling for caries preventive behaviors* as measured by:a) adherence to the desired behaviorb) prevention of dental caries
* diet, oral hygiene, dental attendance, fluoride use
Summary of EvidenceSummary of Evidence
Of the 11 questions….
• 8 questions have no studies or poor evidence
• 3 questions have fair evidence– Professional adherence to guidelines for
prescribing fluoride supplements– Caries reducing benefits from fluoride
supplements– Caries reducing benefits from fluoride varnish
Bader, Rozier et al. Am J Prev Med 2004.
Fluoride VarnishFluoride Varnish • First introduced in 1964; has been used
widely in European countries since 1980’s.
• Approved by the FDA for use in the U.S. in 1994 as a cavity liner and for treatment of hypersensitive teeth.
• Caries prevention is considered an off-label use.
Fluoride Varnish ProductsFluoride Varnish Products• 5% NaF in resin carrier
(2.26% F, 22.6 mg/mL or 22,600 ppm F)– Duraphat (Colgate)– DuraFlor (Medicom)– CavityShield (Omnii)– Vanish (3M ESPE)
• 1% difluorsilane in polyurethane
(0.1% F, 1.0 mg/mL F or 1,000 ppm F)– Fluor Protector (Ivoclar-Vivadent)
NO CLINICAL TRIALS
Is Fluoride Varnish EffectiveIs Fluoride Varnish Effectivein Primary Teeth?in Primary Teeth?
• 6 studies– 4 Duraphat (5% NaF)– 2 Fluor Protector (1% difluorsilane)
• 3 RCTs had consistent findings – reductions of 37% to 63%
• 3 CCTs found consistent benefit– 1 of 3 statistically significant
Fluoride Varnish StudyFluoride Varnish Study
A 2-year randomized, dental examiner masked clinical trial to determine the efficacy of FV and parental counseling in preventing ECC
Counseling + FV 2x/yearCounseling + FV 1x/yearCounseling only
Weintraub et al., 2005
Dental Caries IncidenceDental Caries Incidence by Treatment Groupby Treatment Group
0
5
10
15
20
25
30
35
40
45
0 1 2
p < 0.001; n=280
3-4
%
Number of Applications
PreventiveFraction 95% CI
Varnish 40% 9-72%
Gel 21% 14-28%
Rinse 26% 22-29%
Toothpaste 24% 21-28%
Fluoride TherapyFluoride Therapy
Marinho Adv Dent Res 2008
27%27%
61%61%
63%63%
29%29%
Geographic Disparities in ECCGeographic Disparities in ECC
Response in NCResponse in NC
• 1997: Pilot “Smart Smiles”
• 2000: Medicaid demonstration “Into the Mouths of
Babes” (IMB)
Primary medical care model
Goals of IMBGoals of IMB
• Increase access to preventive dental care for low income, preschool-aged children
• Reduce the prevalence of ECC in low-income children
• Reduce the burden of treatment needs on a dental care system already stretched beyond its capacity to serve young children
Will it work?Will it work?“The North Carolina study…. related the impact of a 2-hour infant oral health training course on pediatricians’ practices...
I cannot imagine that a 2-hour crash course in any scientific discipline can make a meaningful
impact, particularly on something as complex as caries risk assessment.”
John RutkauskasExecutive Director, AAPDOctober 2003
Questions?Questions?• What services should PCCs provide?
• What is the best way to train them?
• How many will adopt once trained?
• Will access to preventive services increase?
• How are dental outcomes affected? – Caries-related treatments
– Costs
– ECC experience
– Oral-health related quality of life
• Oral evaluation / referral
• Counseling
• Fluoride therapy
Scope of ServicesScope of Services
What We’ve LearnedWhat We’ve Learned
• Preventive services– More than 3,000 providers trained– Easily integrated into practice– More than 400 participating practices– Wide geographic distribution– Increased access
- 40% of well-child visits- Physician preventive visits 4x greater than dentists- Multiple visits 20 times greater in medical offices
– Parents report high levels of satisfaction
Number of Visits Per YearNumber of Visits Per Year
0
20,000
40,000
60,000
80,000
100,000
120,000
2000 2001 2002 2003 2004 2005 2006 2007
Average annual increase = 21%
Visits
What We’ve LearnedWhat We’ve Learned
• Physicians’ referral practices– Overall rate = 2.8%– With tooth decay = 33% (vs. 0.2%)– 3-fold increase in use (36% vs. 12%)
• Oral health outcomes– Reduced caries-related treatment needs
by 12% to 39%– Reduced tooth decay by 24% to 36%
Referral EffectivenessReferral Effectiveness
IMBVisit
N=24,403
Referred (33%)
NotReferred
(67%)
Referred(1%)
Not Referred
(99%)
Visit 35.6%
12.0%
11.9%
2.5%
ECC(5%)
No ECC(95%)
Response in NC (Con’t)Response in NC (Con’t)
• 1997: “Smart Smiles”
• 2000: “Into the Mouths of Babes”
• 2006: “Carolina Dental Home”• 2007: “Priority Oral Health Risk Assessment
and Referral Tool” (PORRT) Initiative
• 2008: “ZOE” Early Head Start Initiative
Expansion of primary medical
care model
“Every infant should receive an oral health risk assessment from his/her primary health care provider or qualified health care professional by 6 months of age.”
“Parents or caregivers should establish a dental home for infants by 12 months of age.”
Guidelines for Infant Oral Health Care. AAPD Reference Manual, V29 No7, 2008.
AAP Committee on Practice / Ambulatory Medicine and Bright Futures Steering Committee Recommendations for Preventive Pediatric Health. Pediatrics, 2007.
AAPD & AAP Guidelines for AAPD & AAP Guidelines for Age of 1Age of 1stst Dental Visit Dental Visit
37
Question % Agree
Parents≠
All children should be checked by a dentist around the time the first baby tooth comes in.
Physicians†
Referral to a dentist by 12 months of age should be part of routine well-child care visits?
43.8%
26.5%Dentists‡
A child should receive his or her first dental exam by one year of age.
48.4%
≠All EHS programs in NC. †dela Cruz et al., Pediatrics, 2004.‡Prada E et al., 2008.
Guideline AwarenessGuideline Awareness
Reviewer’s Name
• Review of risk-assessment guidelines
• Systematic review of the literature on risks
• Experience with PORRT in Carolina Dental Home
PPriority riority OOral Health ral Health RRisk Assessmentisk Assessment & & RReferral eferral TTool (PORRT)ool (PORRT)
0 10 20 30 40 50 60 70
Percent
Sleep with bottleFamily has dental problems
No fluoride in waterFluoride toothpaste not used
Drink juice between meals
Other oral conditionDental caries
Enamel defectsWhite spot lesions
Visible plaque
Behavioral
Clinical
Percent of PatientsPercent of Patients with Risk Factorswith Risk Factors
n-=1,825;Not mutually exclusive categories
Referral GuidelinesReferral Guidelines
Cavitationor CSHCN
White spot lesionsEnamel defectsOther concerns>3 risk factors
<3 risk factors
Pediatric dentist
General dentist
Physician manages caries risk
Yes (6%)
No
Yes (23%)
No (72%)
Percent of Children ReferredPercent of Children Referred
63
24
6
71
59
3
0
10
20
30
40
50
60
70
80
Cavitated White spots > 2 risk factors
Baseline
Followup
%
Sufficient Evidence?Sufficient Evidence?• Physicians will expand oral health services,
increasing access:– Risk assessment – Fluoride varnish
• Evidence is emerging to support effectiveness of model as a way to address disparities
• Medical, dental, pubic health and social services are yet to be fully integrated, and evidence about how to do this is lacking
73-2001. Resolved, that it be policy of the American Dental Association that topical application of fluoride varnish is a part of comprehensive dental care which requires an examination and supervision by a licensed dentist.
ADA Resolution:ADA Resolution:Application of Fluoride VarnishApplication of Fluoride Varnish
Trans.2001:430-432.ADA House of Delegates
Expected Medical PracticeExpected Medical Practice
• Oral health risk assessment
• Help establish dental home at 12-18 mo.
• Counsel parents
• If no dental home, continue to:
– Counsel parents
– Apply fluoride varnish
Preventive Oral Health for Pediatricians. Pediatrics. 2008;122:1387-94.
Stage of Adoption of Medical Model by State Medicaid Programs
= No Initiative in place; no plans for one (n=13)
= Existing Program (n=28)= Plans to implement initiative in next 12 months (n=10)
3 states confirmed by telephone (Mississippi, Illinois, West Virginia)
1 state by guidelines (Wisconsin)
RI
TXFL
NC
CA
OR
WA
AZ NM
UT
NV
ID
MT
CO
WY
HI
AK
NE
SD
ND
OK
KS
IA
MO
WI
MN
LA
AR
IL
MI
GA
TN
KY
INOH
MS AL
WV VA
MEVT
NH
NY
PAMD
NJ
DC
MACT
SC
Delaware
Sams et al., 2009.
AAPD ‘Talking Points’AAPD ‘Talking Points’“AAPD policy does not support the application of fluoride varnish absent a comprehensive dental exam. Current AAPD policy supports the delegation of fluoride application to auxiliary dental personnel or other trained allied health professionals, by prescription or order of a qualified dentist, after a comprehensive oral examination has been performed. Fluoride varnish interventions are not a substitute for the establishment of a dental home.”
AAPD perspective on physicians or other non-dental providers applying fluoride varnish. Talking points. June 2006.
It’s been a It’s been a wild ride!wild ride!
Screenin
g?
Referral?
Counseling?
Fluoride?
Diet?
Risk Assessment?CME?
Tx?
AcknowledgementsAcknowledgements Funding sources
– Appalachian Regional Commission– Centers for Medicare and Medicaid Services– Health Resources and Services Administration– Centers for Disease Control and Prevention– National Institutes of Health (NIDCR)– NC Department of Health and Human Services
Early Childhood Oral Health Collaborative (ECOHC)– NC Division of Medical Assistance– NC Chapter AAP– NC Academy of Family Physicians– NC Oral Health Section– UNC-CH School of Dentistry– UNC-CH Gillings School of Global Public Health– NC Division of Child Development, Head Start Collaboration Office
– NC Dental Society– El Pueblo, Inc.
……coordination of preventive and treatment services coordination of preventive and treatment services
among physicians, dentists and community programs among physicians, dentists and community programs
will allow communities to manage and improve the oral will allow communities to manage and improve the oral
health of all children so that they begin school with no health of all children so that they begin school with no
untreated tooth decay…untreated tooth decay…
Thank You!