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Princeton Scientific Instruments, Inc. www.prinsci.com Ph: 732-274-0774 Princeton Scientific Instruments, Inc. 7 Deer Park Dr, Monmouth Junction, N.J. 08852

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Page 1: Princeton Scientific Instruments

Princeton Scientific Instruments, Inc.

www.prinsci.comPh: 732-274-0774

Princeton Scientific Instruments, Inc.7 Deer Park Dr, Monmouth Junction, N.J. 08852

Page 2: Princeton Scientific Instruments

Princeton Scientific Instruments is a small, dynamic company engaged in mechanical, electrical, electronic, software engineering services and research. We have a core group of employees responding quickly to changing customer demands and a bullpen of scientists and engineering consultants available to us. PSI has been in business more than 30 years, originally focused on developing CCD cameras for scientific use. Over the years we have branched out into areas involving electro-optical systems. Customers include commercial, government and academia.

Customers have included :

PSI History

www.prinsci.comPh: 732-274-0774

Princeton Scientific Instruments, Inc.7 Deer Park Dr, Monmouth Junction, N.J. 08852

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• Air Force• Army• BANC3• DARPA• Department of Energy• General Dynamics• Johnson and Johnson• National Institute of Health• NASA

• Navy• Princeton Plasma Physics Laboratory• Princeton Power Systems• Princeton University• Sarnoff/SRI • Sci-in Tech• Sensors Unlimited• University of Arizona Lunar and Planetary Laboratory

Page 3: Princeton Scientific Instruments

PSI Capabilities

www.prinsci.comPh: 732-274-0774

Princeton Scientific Instruments, Inc.7 Deer Park Dr, Monmouth Junction, N.J. 08852

Electronic Circuit Design• Spice Simulation• Orcad Schematic Capture• PCB (Printed Circuit Board) Layout• Analog - amplifiers, filters • Digital – FPGA, Microcontrollers

Software• LabVIEW™ for Data Acquisition & Control• Microcontroller coding

Mechanical Design and Drafting• CAD ( Computer Aided Design )• 3D Modeling• 2D Mechanical Drawings• Artwork for screen printing and laser marking

Optical interface & integration • Filter, Lens, beam splitter selection• Photo detectors, LEDs, Lasers

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Assembly• In house or subcontract• Electronic• Electrical• Mechanical• Optical

Selection, Coordination and Supervision of• Machine Shop, Full CNC machining capabilities• Plating, Anodizing, Hard Coat and Powder Coat• Screen printing and Laser Marking

Vacuum System experience• CCD dewars

Temperature chamber • Temperature range -30 to 100 C

Page 4: Princeton Scientific Instruments

We were tasked with packaging and integration of laboratory instruments and/or designing new instruments by a customer in the skin care product industry. The skin measurement instruments we have been involved with over the past 2+ years are:

• Diffuse Reflectance Spectrometer (DRS) - Visible light reflectance/absorption• Compact Diffuse Reflectance Spectrometer (CDRS) • Fast Diffuse Reflectance Spectrometer (FDRS)• Spectrofluorometer (SFM) - Fluorescence by exciting the skin in one wavelength

and measuring the resulting fluorescence in a different wavelength• Skin Displacement Instrument (SDI) - Skin softness by blowing air on the skin and

measuring the displacement with a laser measuring system• Reviscometer (RVM) - Speed of sound through skin• Dielectric Properties of Skin (DPSI) - Skin resistance• Macro Skin Fluorescence Imaging Probe (MSFIP) – Fluorescence microscope • Multichannel Clinical Imaging System (MCCIS) - Facial DRS

PSI designed, assembled, modified and tested the systems in house.

Projects for a recent Customer

www.prinsci.comPh: 732-274-0774

Princeton Scientific Instruments, Inc.7 Deer Park Dr, Monmouth Junction, N.J. 08852

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Page 5: Princeton Scientific Instruments

Diffuse Reflectance Spectrometer (DRS)

Instrument Description: Used to measure reflectance, absorbance and transmission of Visible light on the skin. Thermo Electric Cooled (TEC) CCD spectrometer, quartz light source. Custom Bifurcated Fiber Optic Probe Instruments delivered with laptop and installed software. Project Disciplines: Packaging, Software, Wiring, Mechanical assembly

Electro-Mechanical Packaging

Final Product2D Machining drawing

3D Cad Model

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Page 6: Princeton Scientific Instruments

Diffuse Reflectance Spectrometer (DRS)

Software Main Screen with Spectrometer output looking at fluorescent room light

Wiring Diagram

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Page 7: Princeton Scientific Instruments

CDRS (Compact Diffuse Reflectance Spectrometer) Optical Funnel version

Instrument Description: Replace the Quartz Halogen Lamp with 4 LED’s and the spectrometer with Silicon detector used in the DRS instrumentProject Disciplines: Packaging, Mechanical Design, Electrical design, Software, Wiring, Mechanical

assembly

Printed Circuit Board3D Cad Model

Simplified Block Diagram

Optical Funnel cut-away view

Optical funnel

SMA optical connectors

Silicon Detector

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Page 8: Princeton Scientific Instruments

Software: Uses the public domain DRS Algorithm to calculate Oxy Hb, Deoxy Hb, Melanin and Scattering using the 4 LEDs. Software operates by turning each of the LED’s on in sequence then recording the reflected spectra with an off the shelf DAQ module. Data is recorded to a text file.

Screen shot of the CDRS software, with strip chart recording

Led Single values popup window

CDRS (Compact Diffuse Reflectance Spectrometer) Optical Funnel version

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Page 9: Princeton Scientific Instruments

FDRS (Fast Diffuse Reflectance Spectrometer)

This instrument is comprised of a Princeton Instruments spectrometer and can acquire spectra at ~100 frames per second. In addition to performing the same calculations as a DRS, the higher speed acquisition can also detect lymphatic oscillations occurring at ~10Hz. This project consisted mainly of customizing software developed for the Spectrofluorometer.

FDRS Instrument Picture

FDRS screen shot of software

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Page 10: Princeton Scientific Instruments

SFM (Spectrofluorometer)This system is used to measure fluorescence of the skin, and is comprised of a monochromator, spectrometer, 2 filter wheels and a Xenon Light source. The project involved packaging and some software modifications in LabVIEW.

Front and rear picture of theSpectrofluorometer system

Screen shot of the software looking at a fluorescent room light

Spectrofluorometer optical path10

Page 11: Princeton Scientific Instruments

2D Machining drawing

Assembled Probe adapter housing Machined from a STEP file

RVM (Reviscometer)

This project is a modification to an existing instrument made by Courage + Khazaka electronic GmbH. This probe uses 2 Piezo transducers, one as a transmitter and the other as a receiver, in order to measure the speed of sound through the skin. The original instrument required the user to manually move the probe. PSI automated the system by putting the probe in a housing with motors to provide the required movements.

3D Frame

Frame and components

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Page 12: Princeton Scientific Instruments

RVM (Reviscometer)This project is a modification to an existing instrument made by Courage + Khazaka electronic GmbH. This probe uses 2 Piezo transducers, one as a transmitter and the other as a receiver, in order to measure the speed of sound through the skin. The original instrument required the user to manually move the probe. PSI automated the system by putting the probe in a housing with motors to provide the required movements.

Screen Shot of a typical Gaussian measurement

System Block Diagram

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Page 13: Princeton Scientific Instruments

A lab instrument for development of customized sequence steps for VI characterization of the skin. Sequences can produce ramp up, ramp down, or DC voltages.

The left plot is an Up / Down ramp demonstrating characteristic hysteresis of the skin. The right plot is a DC Step test 1V – 0V using a test probe with a 500K resistor and a .1uF capacitor in series.

This device uses a lab power supply, capable of delivering 200V at >50mA, therefore a protective interface was designed to trip if current or voltage exceed safe levels.

DPSI (Dielectric Properties of Skin Instrument)

Hysteresis plot

DC Step test with RC Test probe13

Page 14: Princeton Scientific Instruments

MSFIP (Macro Skin Fluorescence Imaging Probe)

This project uses 3 Visible Lasers and a quartz Halogen visible light source along with a filterWheel, shutter, and video camera. Laser beams are confined in fiber optic cables and are routed through an optical switch. An interface board was designed to control the functions of the devices and to provide a Watch Dog Timer for safe laser operation.

Screen Shot imaging a Fluorescence Reference under a transparent grid through a 620nm 14nm FWHM filter 14

Page 15: Princeton Scientific Instruments

MSFIP (Macro Skin Fluorescence Imaging Probe) block Diagram

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Page 16: Princeton Scientific Instruments

MCCIS (Multi Channel Clinical Imaging System) A packaging project

Assembled product

3D Cad views

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Page 17: Princeton Scientific Instruments

3D CAD Modeling

Machined from 2D Drawings

Dynamic Muzzle Reference System

Emitter Optical Tube

Prism Housing

Receiver Unit Assembly

Receiver Unit Housing

A system for measuring the bending of a tank barrel

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Page 18: Princeton Scientific Instruments

Dynamic Muzzle Reference System

Receiver Electronics Unit

Emitter Unit

Receiver Unit

Prism

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Page 19: Princeton Scientific Instruments

Laser Hazard Detector System

Video Processor PC boardAssembled system

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• Visible to Near IR Laser Detection• Intensity, Wavelength, origin angle, Pulsed or CW

Page 20: Princeton Scientific Instruments

This project involves a collaboration with Princeton University (http://www.princeton.edu/mae/ ) Femtosecond Laser Electronic Excitation Tagging (FLEET). This method of tagging the exhaust stream of a jet engine requires no seeding of the gas flow. The laser induced fluorescence is imaged downstream, and the distortion of the laser line can be used to find the velocity profile of the flow. Our fast camera technology is used to provide multiple downstream images with a single data acquisition. Our website has some videos of other fast camera applications. Measurement of turbulent structure in the exhaust of an F-35 for the study of noise generation and control.

FLEET (Femtosecond Laser Electronic Excitation Tagging)

PSI Fast Camera From Professor R. Miles Princeton University 20

Page 21: Princeton Scientific Instruments

Electronic and Mechanical packaging

Black Anodizing and Laser Marking Printed Circuit Board Design and Assembly

Astronomy Telescope Shutter Controller

Sci-in Tech (www.sciin.com) makes large aperture photometric shutters for use in astronomy. These shutters are in use at various telescopes around the world. An embedded micro-controller provides the triggering and timing control to the motors that drive the shutter blades. See the website for more information.

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Page 22: Princeton Scientific Instruments

Princeton Scientific Instruments, Inc.7 Deer Park Drive

Monmouth Junction, NJ 08852Ph 732-274-0774

Fax: 732-274-0775Email: [email protected]

www.prinsci.comPh: 732-274-0774

Princeton Scientific Instruments, Inc.7 Deer Park Dr, Monmouth Junction, N.J. 08852

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