principles of biology biol 100c: introductory biology iii the digestive system dr. p. narguizian...
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Principles of Biology
BIOL 100C:BIOL 100C:Introductory Biology IIIIntroductory Biology IIIThe Digestive SystemThe Digestive System
Dr. P. NarguizianFall 2012
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OBTAINING AND PROCESSING
FOOD
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Animals ingest their food in a variety of ways
Most animals have one of three kinds of diets
– Herbivores, plant-eaters—cattle, snails, sea urchins
– Carnivores, meat-eaters—lions, hawks, spiders
– Omnivores, eating both plants and other animals—humans, roaches, raccoons, crows
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Animals obtain and ingest their food in different ways
– Suspension feeding
– Substrate feeding
– Fluid feeding
– Bulk feeding
Animals ingest their food in a variety of ways
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Caterpillar Feces
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Overview: Food processing occurs in four stages
Food is processed in four stages
– Ingestion
– Digestion
– Absorption
– Elimination
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Mechanicaldigestion
Piecesof food
Food
Chemical digestion(hydrolysis)
Nutrientmoleculesenter bodycells
Smallmolecules
Undigestedmaterial
DigestionIngestion 21 Absorption3 Elimination4
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Mechanical digestion breaks food down into smaller pieces
– Smaller pieces are easier to swallow
– Smaller pieces have more surface area exposed to digestive fluids
Overview: Food processing occurs in four stages
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Chemical digestion breaks down large organic molecules into their components
– Proteins split into amino acids
– Polysaccharides and disaccharides into monosaccharides
– Nucleic acids into nucleotides
Overview: Food processing occurs in four stages
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Protein-digestingenzymes
Polysaccharide
Macromolecule
Protein
Carbohydrate-digestingenzymes
Components
Amino acids
MonosaccharidesDisaccharide
Nucleic acid-digestingenzymes
NucleotidesNucleic acid
Fat-digestingenzymes
Fat Glycerol Fatty acids
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Digestion occurs in specialized compartments
Sponges digest food in vacuoles
Most animals digest food in compartments
– Enzymes break down the food
– Food particles move into cells lining the compartment
– Undigested materials are expelled
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Cnidarians and flatworms have a gastrovascular cavity with a single opening, the mouth
– Food enters the mouth
– Undigested food is expelled back out the mouth
Digestion occurs in specialized compartments
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Food(Daphnia,a waterflea)
Gastrovascularcavity
Food particleengulfed
Soft tissuesdigested
Tentacle
Mouth
Digestiveenzymesreleased froma gland cell
Food particledigested infood vacuole
4
3
2
1
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Most animals have an alimentary canal with
– Mouth
– Anus
– Specialized regions
Digestion occurs in specialized compartments
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Mouth
Pharynx
Esophagus
Crop
Gizzard Anus
Intestine
Earthworm
Dorsal fold
Interior of intestine
Wall of intestine
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EsophagusMidgut
Mouth
Crop
Grasshopper
Anus
HindgutGastric pouches
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Mouth
Esophagus
Crop
Gizzard
Anus
Intestine
Bird
Stomach
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HUMAN DIGESTIVE SYSTEM
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Digestive System I: The Upper Gastrointestinal Tract
http://education-portal.com/academy/lesson/digestive-system-i-the-upper-gastrointestinal-tract.html
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The human digestive system consists of an alimentary canal and accessory glands
Alternating waves of contraction and relaxation by smooth muscle in the walls of the canal move food along in a process called peristalsis
Sphincters control the movement of food into and out of digestive chambers
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The pyloric sphincter
– Regulates the passage of food from the stomach to the small intestine
– Limits the upward movement of acids into the esophagus
The human digestive system consists of an alimentary canal and accessory glands
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Mouth Salivaryglands
Esophagus
Gall-bladder
Liver
Pancreas
Smallintestine
Stomach
RectumAnus
Largeintestine
A schematic diagram of thehuman digestive system
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Pharynx
Esophagus
Oralcavity
Tongue
Mouth
Salivaryglands
Gall-bladder
Liver
Pancreas
Smallintestine
Rectum
Anus
Largeintestine
Esophagus
Stomach
Smallintestine
Sphincter
Sphincter
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Digestion begins in the oral cavity
Teeth break up food, saliva moistens it
– Salivary enzymes begin the hydrolysis of starch
– Buffers neutralize acids
– Antibacterial agents kills some bacteria ingested with food
The tongue tastes, shapes the bolus of food, and moves it toward the pharynx
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Opening of asalivary gland duct
Salivaryglands
Tongue
Incisors
Premolars
Molars
“Wisdom”tooth
Teeth
Canine
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After swallowing, peristalsis moves food through the esophagus to the stomach
The trachea conducts air to the lungs
The esophagus conducts food from the pharynx to the stomach
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Epiglottisup
Pharynx
Esophagealsphincter
Bolus offoodTongue
Esophagus
Larynx
Trachea
Sphincter contracted
Epiglottisdown
Esophagus
Larynxup
Sphincter relaxed
Epiglottisup
Sphincter contracted
Larynxdown
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The swallowing reflex
– Food moves from the pharynx into the esophagus
– The swallowing reflex prevents food from entering the trachea
– A coughing reflex helps expel materials that accidentally enter the trachea
After swallowing, peristalsis moves food through the esophagus to the stomach
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Esophageal sphincter(contracted)
Bolus offood
Muscles contract,constricting passagewayand pushing bolus down
Stomach
Bolus offood
Muscles relax,allowing passagewayto open
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The stomach stores food and breaks it down with acid and enzymes
Acid
– pH 2
– Parietal cells secrete hydrogen and chloride ions, which combine to make HCl
– Acid kills bacteria and breaks apart cells in food
Pepsinogen and HCl produce pepsin
– Pepsin production activates more pepsinogen production—positive feedback
– Pepsin begins the chemical digestion of proteins
– Acidic gastric juices mix with food to produce acid chyme
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What prevents the gastric juices from digesting the walls of the stomach?
– Mucus helps protect against HCl and pepsin
– New cells lining the stomach are produced about every 3 days
The stomach stores food and breaks it down with acid and enzymes
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Interior surfaceof stomach
Lumen (cavity)of stomach
Stomach Gastrin
Esophagus
Sphincter
Sphincter
Smallintestine
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Interior surfaceof stomach
Pits
Release of gastric juice(mucus, HCl, and pepsinogen)
Epithelium
Gastricgland
Mucouscells
Chief cells
Parietal cells
Pepsin(activeenzyme)
Pepsinogen
H+
Cl–
HCl2
3
1
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The small intestine is the major organ of chemical digestion and nutrient absorption
Small intestine is named for its smaller diameter—it is about 6 meters long
Alkaline pancreatic juice neutralizes acid chyme and its enzymes digest food
Bile, made in the liver and stored in the gall bladder, emulsifies fat for attack by pancreatic enzymes
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Gall-bladder
Pancreatic juice
Liver Bile
Acid chyme
Pancreas
Stomach
Intestinalenzymes
Duodenum ofsmall intestine
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Digestive System II: The Lower Gastrointestinal Tract
http://education-portal.com/academy/lesson/digestive-system-ii-the-lower-gastrointestinal-tract.html
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Enzymes from cells of the intestine continue digestion
The small intestine is the major organ of chemical digestion and nutrient absorption
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Surface area for absorption is increased by
– Folds of the intestinal lining
– Fingerlike villi
The small intestine is the major organ of chemical digestion and nutrient absorption
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Musclelayers
Largecircular folds
Villi
Lumen
Nutrientabsorption
Intestinal wall
Veinwith blooden route tothe liver
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Nutrients pass across the epithelium and into blood
Blood flows to the liver where nutrients are processed and stored
The small intestine is the major organ of chemical digestion and nutrient absorption
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Lymphvessel
Bloodcapillaries
Villi
Nutrientabsorption
Epithelialcells
Lumen of intestine Lumen of intestine
Nutrient absorptioninto epithelial cells
Microvilli
Aminoacidsand
sugars
Fats
Blood
Fattyacidsand
glycerol
Epithelial cellslining villus
Lymph
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One of the liver’s many functions is processing nutrient-laden blood from the intestines
Blood from the digestive tract drains to the liver
The liver performs many functions
– Glucose in blood is converted to glycogen and stored in the liver
– Liver synthesizes many proteins including blood clotting proteins and lipoproteins that transport fats and cholesterol
– Liver changes toxins to less toxic forms
– Liver produces bile
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Heart
Hepaticportalvein
Kidneys
Liver
Intestines
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The large intestine reclaims water and compacts the feces
Diarrhea occurs when too little water is reclaimed
Constipation occurs when too much water is reclaimed
Feces are stored in the rectum
Colon bacteria produce vitamins—biotin, vitamin K, B vitamins
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Appendix
– Located near the junction of the small intestine and colon
– Makes a minor contribution to immunity
The large intestine reclaims water and compacts the feces
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Largeintestine(colon)
Endof smallintestine
Appendix
Cecum
Sphincter
Unabsorbedfood material
Anus
Rectum
Smallintestine
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EVOLUTION CONNECTION: Evolutionary adaptations of vertebrate digestive systems often relate to diet
The length of the digestive tract often correlates with diet
– Herbivores and omnivores have relatively longer digestive tracts than carnivores
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Small intestine
Cecum
Stomach
Colon(large intestine)
Carnivore Herbivore
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Many herbivores have specializations of the gut that promote the growth of cellulose-digesting microbes
– Rumen
– Reticulum
– Omasum
– Abomasum
EVOLUTION CONNECTION: Evolutionary adaptations of vertebrate digestive systems often relate to diet
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Intestine Omasum Rumen
Esophagus
ReticulumAbomasumRumen
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a. g.
h.
i.
j.
k.
l.
m.
b.
c.
d.e.
f.
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You should now be able to
1. Describe the four stages of food processing
2. Describe the main components of the human digestive tract and their functions
3. Explain how teeth and saliva help us swallow
4. Explain why the stomach does not digest itself5. Compare the structures and functions of
the small and large intestines
6. Compare the digestive tracts of carnivores and herbivores