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Over the last 15 years, much has been made of the importance of probiotics for increased health, not just for people, but for animals, too. Substantial research has been conducted with the findings clearly indicating that probiotics can induce a beneficial change in the intestinal microbiota when pathogenic bacteria dominate the GI tract. 1 In their role of promoting digestive health, probiotics also have been found to have a positive impact on immunity. 2 Other benefits of probiotics beyond GI health and immunity have been discovered, and clinical research is still being conducted. The Difference Between Probiotics, Prebiotics and Synbiotics Probiotics, prebiotics and synbiotics have been the focus in the media and many products on the market today, with much touting of their individual or combined benefits. So what are they and how do they work? Probiotics are live, beneficial bacteria that confer a health benefit to the host. 3 They promote healthy digestion, boost the immune system, and contribute to general health and wellbeing. Prebiotics are non- digestible food ingredients that stimulate the growth and/or activity of bacteria in the digestive system. They are actually the food source for probiotics. When probiotics and prebiotics are used synergistically in nutritional supplements, they are referred to as synbiotics. And while many pet owners may not completely understand how probiotics and prebiotics work together or which product may be best for their pet, they are becoming more interested in exploring how a synbiotic product will benefit their dog or cat. Maintaining Balance The microbiota in an animal’s GI tract is a complex ecosystem made up of beneficial and pathogenic bacteria living together in a delicate balance. Many factors can disrupt this balance, including antibiotic use, change in diet, illness, age, and stress. These factors can permit pathogenic bacteria to overpopulate and produce toxins. When this kind of imbalance occurs, the overgrowth of pathogenic bacteria causes irritation to the intestinal lining and results in one or more of these symptoms: diarrhea, excess gas, abdominal pain, constipation, and lethargic behavior. With 70% of an animal’s immune system located in the GI tract, these factors compromise an animal’s ability to fend off pathogens. Introducing a synbiotic supplement to an animal’s diet can help consistently maintain proper GI microbial balance. Not all Probiotics are Equal Probiotics are categorized by genus and species using Latin names such as Lactobacillus helveticus and Bifidobacterium longum. The probiotic selected by a manufacturer for a supplement product is very important because not only are there different genera and species, but also different strains – for example, Lactobacillus helveticus Rosell-52. Research has shown that each probiotic strain has unique benefits, even though the genus and species may be the same. “Choosing the right strain for the proper indication is paramount,” said Dr. Thomas Tompkins, lead research scientist at Institut Rosell Inc. “In mixed strain probiotic products it is important to consider the compatibility between the strains selected. In some probiotic products strains can compete and reduce the efficacy of the others present–so it is important to choose strains that not only happily coexist but act synergistically.” Because each strain has unique benefits, using the right combination of different strains may provide a greater impact on an animal’s health. In one study involving four microbial strains, the combination of all four strains was proven more effective than each individual strain at reducing weight loss and maintaining fecal consistency due to infection. 4 Viability and Quantity Matter The viability and quantity of probiotics in a supplement are also important to the performance of the product. Microencapsulation is vital to protecting the viability when the product is introduced to the acidic environment of the stomach. Stomach acidity can destroy and damage some probiotics. The quantity of probiotics in a pet supplement can also affect product performance. Probiotics are measured in CFUs, colony-forming units. “The important point is to ensure the supplement contains an adequate amount of probiotics to provide health benefits,”says Dr. Tompkins, adding, “If a product contains less than 1 billion CFUs, it may not provide enough beneficial bacteria to properly balance the GI tract.” The Importance of Prebiotics Once the probiotics become rehydrated and active in the GI tract, an adequate food source can aid their survival. Prebiotic fibers provide a source of nutrition for the live probiotics. Prebiotics also provide a food source for the beneficial bacteria already in the GI tract. However, pathogenic bacteria, such as Salmonella and E. coli are unable to utilize these fiber sources. By combining a food source–prebiotics–to the supplement, the survival of the beneficial bacteria–probiotics–may be improved. Introducing a New Kind of Synbiotic Supplement – Synacore Synacore, a new synbiotic supplement manufactured by Van Beek Natural Science, is a unique combination of probiotics, prebiotics, enzymes, and vitamins. Van Beek specifically formulated Synacore with probiotic strains backed by independently conducted and published clinical studies of their individual efficacies. The chosen combination of Synacore’s strains is based on the synergistic actions of well-documented bacteria and yeast strains that offer optimal intestinal support. Probiotics – Choosing the Right Product for Your Practice By Teresa McComb - Biochemist & Product Formulator 26 Messenger | March 2011 practicalpractice

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Page 1: Probiotics – Choosing the Right Product for Your Practice · Research has shown that each probiotic strain has unique benefits ... four strains was proven ... of probiotics to provide

Overthelast15years,muchhasbeenmadeoftheimportanceof

probioticsforincreasedhealth,notjustforpeople,butforanimals,

too.Substantialresearchhasbeenconductedwiththefindings

clearlyindicatingthatprobioticscaninduceabeneficialchangein

theintestinalmicrobiotawhenpathogenicbacteriadominatethe

GItract.1Intheirroleofpromotingdigestivehealth,probiotics

alsohavebeenfoundtohaveapositiveimpactonimmunity.2

OtherbenefitsofprobioticsbeyondGIhealthandimmunityhave

beendiscovered,andclinicalresearchisstillbeingconducted.

The Difference Between Probiotics, Prebiotics and SynbioticsProbiotics,prebioticsandsynbioticshavebeenthefocus

inthemediaandmanyproductsonthemarkettoday,

withmuchtoutingoftheirindividualorcombined

benefits.Sowhataretheyandhowdotheywork?

Probioticsarelive,beneficialbacteriathatconferahealthbenefitto

thehost.3Theypromotehealthydigestion,boosttheimmunesystem,

andcontributetogeneralhealthandwellbeing.Prebioticsarenon-

digestiblefoodingredientsthatstimulatethegrowthand/oractivity

ofbacteriainthedigestivesystem.Theyareactuallythefoodsource

forprobiotics.Whenprobioticsandprebioticsareusedsynergistically

innutritionalsupplements,theyarereferredtoassynbiotics.

Andwhilemanypetownersmaynotcompletelyunderstand

howprobioticsandprebioticsworktogetherorwhichproduct

maybebestfortheirpet,theyarebecomingmoreinterestedin

exploringhowasynbioticproductwillbenefittheirdogorcat.

Maintaining BalanceThemicrobiotainananimal’sGItractisacomplexecosystem

madeupofbeneficialandpathogenicbacterialivingtogetherina

delicatebalance.Manyfactorscandisruptthisbalance,including

antibioticuse,changeindiet,illness,age,andstress.Thesefactors

canpermitpathogenicbacteriatooverpopulateandproduce

toxins.Whenthiskindofimbalanceoccurs,theovergrowth

ofpathogenicbacteriacausesirritationtotheintestinallining

andresultsinoneormoreofthesesymptoms:diarrhea,excess

gas,abdominalpain,constipation,andlethargicbehavior.

With70%ofananimal’simmunesystemlocatedintheGI

tract,thesefactorscompromiseananimal’sabilitytofendoff

pathogens.Introducingasynbioticsupplementtoananimal’sdiet

canhelpconsistentlymaintainproperGImicrobialbalance.

Not all Probiotics are EqualProbioticsarecategorizedbygenusandspeciesusingLatinnames

suchasLactobacillus helveticusandBifidobacterium longum.The

probioticselectedbyamanufacturerforasupplementproductisvery

importantbecausenotonlyaretheredifferentgeneraandspecies,

butalsodifferentstrains–forexample,Lactobacillus helveticus

Rosell-52.Researchhasshownthateachprobioticstrainhasunique

benefits,eventhoughthegenusandspeciesmaybethesame.

“Choosingtherightstrainfortheproperindicationisparamount,”

saidDr.ThomasTompkins,leadresearchscientistatInstitut

RosellInc.“Inmixedstrainprobioticproductsitisimportant

toconsiderthecompatibilitybetweenthestrainsselected.

Insomeprobioticproductsstrainscancompeteandreduce

theefficacyoftheotherspresent–soitisimportanttochoose

strainsthatnotonlyhappilycoexistbutactsynergistically.”

Becauseeachstrainhasuniquebenefits,usingtheright

combinationofdifferentstrainsmayprovideagreaterimpact

onananimal’shealth.Inonestudyinvolvingfourmicrobial

strains,thecombinationofallfourstrainswasprovenmore

effectivethaneachindividualstrainatreducingweightloss

andmaintainingfecalconsistencyduetoinfection.4

Viability and Quantity MatterTheviabilityandquantityofprobioticsinasupplement

arealsoimportanttotheperformanceoftheproduct.

Microencapsulationisvitaltoprotectingtheviabilitywhenthe

productisintroducedtotheacidicenvironmentofthestomach.

Stomachaciditycandestroyanddamagesomeprobiotics.

Thequantityofprobioticsinapetsupplementcanalsoaffectproduct

performance.ProbioticsaremeasuredinCFUs,colony-formingunits.

“Theimportantpointistoensurethesupplementcontainsanadequate

amountofprobioticstoprovidehealthbenefits,”saysDr.Tompkins,

adding,“Ifaproductcontainslessthan1billionCFUs,itmaynot

provideenoughbeneficialbacteriatoproperlybalancetheGItract.”

The Importance of PrebioticsOncetheprobioticsbecomerehydratedandactiveintheGI

tract,anadequatefoodsourcecanaidtheirsurvival.Prebiotic

fibersprovideasourceofnutritionfortheliveprobiotics.

Prebioticsalsoprovideafoodsourceforthebeneficialbacteria

alreadyintheGItract.However,pathogenicbacteria,suchas

SalmonellaandE. coliareunabletoutilizethesefibersources.

Bycombiningafoodsource–prebiotics–tothesupplement,the

survivalofthebeneficialbacteria–probiotics–maybeimproved.

Introducing a New Kind of Synbiotic Supplement – Synacore Synacore,anewsynbioticsupplementmanufacturedbyVan

BeekNaturalScience,isauniquecombinationofprobiotics,

prebiotics,enzymes,andvitamins.VanBeekspecificallyformulated

Synacorewithprobioticstrainsbackedbyindependently

conductedandpublishedclinicalstudiesoftheirindividual

efficacies.ThechosencombinationofSynacore’sstrainsis

basedonthesynergisticactionsofwell-documentedbacteria

andyeaststrainsthatofferoptimalintestinalsupport.

Probiotics – Choosing the Right Product for Your PracticeByTeresaMcComb-Biochemist&ProductFormulator

26 Messenger|March2011

practicalpracticepractical

Page 2: Probiotics – Choosing the Right Product for Your Practice · Research has shown that each probiotic strain has unique benefits ... four strains was proven ... of probiotics to provide

Probiotics – Choosing the Right Product for Your PracticeByTeresaMcComb-Biochemist&ProductFormulator

Inaddition,Synacore’sprobioticsaremicroencapsulatedwith

apatentedprocesstowithstandtheacidicenvironmentofthe

animal’sstomach.Thetotalprobioticbacteriacountinthe

Synacoredogformulais6billionCFUs.Synacore’scatformulais

1billionCFUs.Thesecountsarehighenoughtodelivertheright

amountofprobioticstopromotethehealthbenefitsdesired.

More than Just a ProbioticTheSynacoreformulasalsocontains2prebiotics,13enzymes,and3

vitaminstoformacompletedailysupplement.Synacoreincludesthe

prebioticsinulinandFOS.Notonlydotheseprebioticsprovidethe

rightfoodfortheprobiotics,theysignificantlyreducefecalodor.5

Enzymesareneededforananimaltobreakdownfood.Some

animalsarenotabletoproduceenoughoftherightenzymes.

Thisputsstressonthedigestivesystem,interferingwithnutrient

absorptionandcausingchronicdigestiveproblems.Sincemost

dogandcatfoodscontainlittleornoenzymes,Synacorecontains

enzymestoimprovenutrientabsorption,increaseenergylevels,

enhanceananimal’smetabolism,andpromoteweightloss.

SynacorealsocontainsvitaminsA,D&E.VitaminAprotectsthe

intestinalmucosaagainstadhesionandinvasionbypathogens.

VitaminDhelpswiththeabsorptionofcalciumandphosphorous,

importantinboneformation.VitaminEhasantioxidantproperties

tobindradicaloxygenmolecules,maintaininghealthytissue.

Synacoreisagranularproductadministeredbybeing

addedtoapet’sfood.ClinicaltrialshaveshownSynacore

tobepleasanttastingandreadilyaccepted.Thestickpack

singledosepackagingisalsosanitaryandeasytouse.

Asthenumberofproductsavailableonthemarketgrows,more

andmoreconcernedpetownerswillturntotheirveterinarian

foranswersonwhichproductisbestfortheirpet.Synacore’s

formulationsaredesignedtoprovidemaximumhealth

benefits,easeofdosingandsuccessfuladministration.

References1.GibsonGR.Effectsofprebioticsonhumanhealth.GutEcology.EdMartinDunitz2002;81-88

2.MacDonald.BacteriaandtheregulationofT-cellimmunefunctioninthegut.GutEcology.57-65.

3.FAO/OMS.GuidelinesfortheEvaluationofProbioticsinFood:JointFAO/WHOWorkingGroupmeeting,LondonOntario,Canada,30April-1May2002

4.BissonJF,HidalgoS,RozanP,MessaoudiM.Preventiveeffectsofdifferentprobioticformulationsontravelers’diarrheamodelinwistarrats:preventiveeffectsofprobioticsonTD.DigDisSci.2010Apr;55(4):911-9.

5.Swanson,K.S.,(2002).SupplementalFructooligosaccharidesandMannanoligosaccharidesInfluenceImmuneFunction,IlealandTotalTractNutrientDigestibilities,MicrobialPopulationsandConcentrationsofProteinCatabolitesintheLargeBowelofDogs.The Journal of Nutrition, Volume 132, no. 5,980-989.

TM

Digestive Support

Maintenance Formulas for Dogs & Cats

More than Just a Probiotic!So what is it then? Synacore is a uniquely formulated synbiotic supplement containing both probiotics and prebiotics that work together to support the growth of “friendly � ora” in the GI tract. Synacore’s formula also includes enzymes and vitamins to aid in digestion and support overall health.

800.346.5311 • www.vanbeeknaturalscience.comFollow us: Facebook.com/VanBeekPets Twitter.com/VanBeekPets 020111

V B

All brands are the property of Van Beek Natural Science ©2011 Van Beek Natural Science All Rights Reserved.

Lactobacillus helveticus Rosell-52

Genus Species Strain

Features• Synergistic bene� ts - ingredients work together to enhance their individual e  ectiveness• Advanced micro-encapsulation to prolong shelf life & ensure survival to the intestine• Each individual strain, identi� ed by a number, has a unique action and location in the GI tract. Synacore’s strains have been speci� cally chosen for their particular action and location. Look for the strain!

1 FREE!Buy 5boxes & receiveMust purchase 5 boxes of same formula to receive 1 free box of like kind. This promotion runs from February 1 thru April 30, 2011. Synacore will be available and ready to ship March 1st.

Introducing

27March2011|Messenger

practicalpracticepractice


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