Product

Introduction

康達生命科學有限公司康達生命科學有限公司康達生命科學有限公司康達生命科學有限公司Contek Life Science Co., Ltd.

Red Algae Peptide Hydrolysate-EDpeptide

The Next Generations of Erectile Dysfunction Cure

� Introduction of small peptides

� Erectile dysfunction and the role Edpeptide plays in it

� Our researches on EDpeptide

What Is “Small Peptides”?

� There are plenty of small peptides (e.g. cytokines, growth factors and enzymes) in human body that play important roles in program initiation.

� Every single small peptide has a specific unique receptor which can regulate gene expression in different kinds of cells.

� Receptor is like a keyhole whereas small peptide is like a key.

The Benefits of Small Peptide Supplements

Traditional natural herbal extracts can only show their effects after being taken for a year or more.

Besides, most of them contain impurities or toxins which can burden the metabolism of body.

The advantages of small peptides

1. Absorbed by the intestinal mucosa in its intact form: small peptides would not be destroyed by human’s digestive enzymes.

2. Rapid and efficient absorption:The time of being absorbed into the circulatory system just like intravenous injections; it acts rapidly on specific organs.

3. The ingredient is pure, does not increase burden of gastrointestinal function

4. Be effective without taking much

Source of EDpeptide

� ConTek utilizes “X-ray crystal diffraction” for screening and has found three types of protein fragments from patented red algae which are effective for erection.

� Patented photoreactor allows red algae to produce large amount of these three types of small peptides without genes modification.

� Functions are further improved by protein chain modification technology of molecular biological engineering to become red algae small peptides.

The Mechanism of Erection

� Sexual arousal (Sex impulse)→ Erectile signal transduction→ Cavernous nerve ending → Regulation of cavernous vasodilatation → Hyperemia of peripheral vascular in corpus cavernosa→ Expansion and hardening of corpus cavernosa→ ERECTION

Erectile signal

Sex Impulse

Regulate cavernous vasodilatation

Cavernous nerve ending receive signal

Hyperemia of peripheral vascular in cavernous tissue

Spongy body expand and harden

ERECTION

The Key Point of Erection – Corpus Cavernosum

Erectile DysfunctionType

Arteriogenic impotence: The blood to the penis is supplied by the arteries. When arteries narrow, they fail to bring in sufficient blood to the penis resulting in erectile dysfunction.

Venogenic impotence: During erection, the veins of the penis close down which hardens the penis. But when the veins leak blood, the penis fails to sustain an erection. It is the most common form which accounts for 30-70% impotence.

Neurogenic impotence: There are nerves control the arteries and veins, which change the blood flow within the penis. An injury to the back or other nerves related to the penis may cause this kind of impotence.

EDpeptide Effect LevelAverage

Good

Erectile DysfunctionType

Impotence from Diabetes Mellitus: DM links to impotence in many ways. According to studies, around 50% of diabetics are patients of male impotence.

Endocrinologic impotence: Endocrinologic impotence occurs due to an imbalance of sex hormones in the blood stream. Nearly 5 to 10% of men suffer from Endocrinologicimpotence.

Mixed impotence: More than one factor causes impotence.

Psychogenic impotence:Impotence at times can occur due to some sort of psychological complications. In such cases, there will be no physical factors accompanying erectile dysfunction.

EDpeptide Effect LevelAverage

Good

康達生命科學有限公司康達生命科學有限公司康達生命科學有限公司康達生命科學有限公司Contek Life Science Co., Ltd.

How to Improve ED

�Improve blood circulation in penis.

�Repair of peripheral nerve fibers in cavernous.

�"Sponge protein peptide of transforming growth factor TGF-β1" maintain the normal self-healing function.

�Supplementary long-term conditioning.

Contents of EDpeptide

� VEGF-ED: The major role is to inhibit ACEI and VEGF. It initiates nitric oxide synthase to relax penile smooth muscle, helps in sponge angiogenesis, improves blood flow in cavernous tissue to erect penis. Also, it accelerates cavernous tissue repair when adequate nutrients and oxygen are supplied.

� NGF-ED: It can repair cavernous nerve to ensure signal has been delivered to every part for erection initiation.

� TGF-ED:It guides precisely the delivery of nutrients to cavernous nerves and thereby repairs damaged nerves.

Functions of EDpeptide� Regulates endocrine function: helps in male estrogen supplementation

and secretion as well as increases sex hormone in blood.� Promotes penis congestion and stiffness:promotes secretion of nitric

oxide and nitric oxide synthesis, allows dilation of penile arteries and capillaries as well veins constriction to congest, expand and harden penis.

� Arteries dilation and improves blood circulation: reduces blood sedimentation, increases blood flow in penis, starts the sponge growth factors, enhances penis length and diameter.

� Improves persistence:inhibits ejaculation nerve, reduces excitability to delay ejaculation, and therefore prolongs sexual orgasm.

� Repairs nervous system:delays the degradation of gonadal axis function, prevents the changes of neurotransmitter in brain as well as improves effectively male sexual desire, enhances sexual pleasure, balances sexual excitement and prolongs sexual intercourse.

� Enhances immunity: increases blood oxygen and nutrients that carried by red blood cells in blood, promotes body metabolism, delays cell ageing and enhances immune functions.

How Dose EDpeptide Works

EDpeptide

A small amount of venous blood supply nutrients

Vein Closed

Atresia Influx of arterial blood

Erectile

Normal

How Dose EDpeptide Works

EDpeptide

EDpeptide NO cGMPPituitary Sympathetic

The NO quantity in rats’ corpus cavernosum

The NO quantities in the saline, 4 ml, 9 ml, and 13 ml Edpeptidegroups to feed the rats are respectively 2.2±±±±1.1, 4.2±±±±2.1, 10.6±±±±4.7, 24.9±±±±10.9 pmol/0.2 g tissue. It is discovered that the rats fed with 4ml, 9 ml and 13 ml solutions prove to have increased NO quantity as compared to the rats fed with saline.

control

The cGMP quantity in rats’ corpus cavernosum

The cGMP quantities in the saline, 4 ml, 9 ml, and 13 ml Edpeptidegroups to feed the rats are respectively 2.2±±±±1.1, 4.2±±±±2.1, 10.6±±±±4.7, 24.9±±±±10.9 pmol/0.2 g tissue. It is discovered that the rats fed with 9 ml and 13 ml solutions prove to have increased cGMP quantity as compared to the rats fed with saline. But rats fed with 4 ml solution prove no significance in statistics. control

Effect on internal pressure (hardness)

Rats fed with 4 ml cause extension effectiveness on 28.1±±±±6.4%, 39.0±±±±3.3%, and 77.1±±±±5.9% (the higher the harder)

Rats fed with 9 ml cause extension effectiveness on 30.5±±±±5.4%, 44.5±±±±7.5%,

Rats fed with 9 ml solution prove obvious increase in compare to 4ml and control group.

By using EFS(electrical field stimulation) to mimic sexual stimulation and test the hardness of corpus cavernosum

Safety Studies by Level Biotech

Pass Tests:

� Acute Toxicity Study in Rats

� Bacterial Reverse Mutation Test

� In vitro Mammalian Chromosome Aberration Test

� In vivo Mammalian Erythrocyte Micronucleus Test

Does Not Contain Ingredients of Western Medicine

– Test reports of SGS Taiwan, HSA Singapore as well as multinational patent No.

Selling Points

1.Directly absorbed by the intestinal mucosa2. Rapid and efficient absorption3. Will not cause the stomach to absorb the burden; in the metabolism, also won’t cause kidney burden.4.The production of proteins with enzymatic function of short-chain peptide, a protein derived from the multi-enzymatic hydrolysis.5. Even if taking everyday are not harmful to health. But Viagra can’t taking everyday.6. No serious side effects

Compared with Drugs in the Market

Additional Remark

How to use EDPeptide (250mg) and caution:� Take one EDPeptide tablet per day� Take one tablet 60~90minutes before the sexual

intercourse� Do not take: if you are taking tea, juice, sparkling

drink(beer, Coke) and other medicine for heart or blood vessel disease