product note photon detection solutions...gigahertz photon detection module 3 figure 4. fast...

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Introduction PerkinElmer’s new Gigahertz Photon Detection module (GPDM) provides ultra-low- light level detection in DC mode. The DC mode of operation with single photon sensitivity makes the GPDM module superior to traditional counting circuits with their high light level performance limitation. The GPDM offers the world’s highest dynamic range between 1 cps and 1 Gcps in a single operating mode, coupled with extremely low noise performance. The fully-equipped module includes the Channel Photomultiplier, the high voltage supply, analogue current amplifier, A to D conversion, and a microcontroller with USB/SPI interface, allowing for adapting to a wide range of applications. Additional features like the synchronization I/O offer the ability to synchronize the measurement with other devices, such as flash lamp trigger. Applications Multimodal analytical analysis Luminescence spectroscopy Time-resolved fluorescence High through-put screening DNA & cell analysis Microplate reading Features and Benefits World’s highest dynamic counting range between 1 cps and 1 Gcps in a single operating mode Extremely low background noise High gain 4 different operating modes Variable interface options Best suited for multimodal analytical applications Gigahertz Photon Detection Module Gigahertz Photon Detection Module for Analytical and Clinical Diagnostic Applications Figure 1. Block Diagram Photon Detection Solutions PRODUCT NOTE www.perkinelmer.com

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Page 1: Product Note Photon Detection Solutions...Gigahertz Photon Detection Module 3 Figure 4. Fast Switching Mode Figure 5. HV Reduction Mode PMT dynamic 1e7 range Range of MD electronics

IntroductionPerkinElmer’s new Gigahertz Photon Detection module (GPDM) provides ultra-low-light level detection in DC mode. The DC mode of operation with single photon sensitivity makes the GPDM module superior to traditional counting circuits with their high light level performance limitation. The GPDM offers the world’s highest dynamic range between 1 cps and 1 Gcps in a single operating mode, coupled with extremely low noise performance.

The fully-equipped module includes the Channel Photomultiplier, the high voltage supply, analogue current amplifier, A to D conversion, and a microcontroller with USB/SPI interface, allowing for adapting to a wide range of applications. Additional features like the synchronization I/O offer the ability to synchronize the measurement with other devices, such as flash lamp trigger.

Applications

Multimodal analytical analysis•

Luminescence spectroscopy•

Time-resolved fluorescence•

High through-put screening•

DNA & cell analysis•

Microplate reading•

Features and Benefits

World’s highest dynamic counting range between •1 cps and 1 Gcps in a single operating mode

Extremely low background noise •

High gain•

4 different operating modes•

Variable interface options•

Best suited for multimodal analytical applications•

Gigahertz Photon Detection Module

Gigahertz Photon Detection Module for Analytical and Clinical Diagnostic Applications

Figure 1. Block Diagram

Photon Detection SolutionsP r o d u c t N o t e

www.perkinelmer.com

Page 2: Product Note Photon Detection Solutions...Gigahertz Photon Detection Module 3 Figure 4. Fast Switching Mode Figure 5. HV Reduction Mode PMT dynamic 1e7 range Range of MD electronics

2

Notes:

1) See below performance characteristics

2) CPM characteristics can be matched to the application’s requirements – see spectral response curve

3) Gain pre-set to optimal single photons sensitivity

4) Actual output information is RLU (relative light unit) – counts per second is the calculated value based on RLU

To enable best performance characteristics for different application depending requirements, the GPDM offers different operating modes, which can either be selected manually or will be set automatically:

Real Counting Mode

Straight Output Mode

Fast Switching Mode

HV Reduction Mode

1 CPS – 10 k CPS

1 CPS – 50 M CPS

1 CPS – 1 G CPS

– 10 G CPS

Real Counting Mode: Represents the digital information whether a photon has been detected or not. This method can be used for internal count rate – Rel. light unit calibration

Straight Output Mode: Output information in rel. light units, no internal switching required

Fast Switching Mode: Output information in rel. light units, extended dynamic range by fast Gain switching

HV Reduction Mode: HV Reduction Mode: Output information in rel. light units, extended light intensity range by manual HV reduction

Parameter

Supply voltage

Supply current

Detection range1

Switching dead timein fast switching mode

QE2

CPM gain3

Sample time

Acquisition time

Interface

Min.

5.0

111

3e5

1E3

2001

3

Typ.

5.3

300

1

20%

adjustable

2

-

Max.

5.6

1e45e71e9

1e10

20

5 0005 000

200

8

Units

VDC

mA

counts per second4

counts per second4

counts per second4

counts per second4

ms

ms

photoelectrons / photons

msms

µs

Mbit / second

MHz

Condition

Real counting modeStraight output modeFast switching modeHV reduction mode

w/o offset calibration

including offset calibration

λpeak

Continuous data output(under development)

Width of measurement window for flash sequence

measurements

USB 2.0

SPI(under development)

Preliminary Technical Data1

Operating Modes2

Gigahertz Photon Detection Module

Page 3: Product Note Photon Detection Solutions...Gigahertz Photon Detection Module 3 Figure 4. Fast Switching Mode Figure 5. HV Reduction Mode PMT dynamic 1e7 range Range of MD electronics

GigaHertz Photon Detection ModuleMeasurement Bandwidth Real Counting Mode at

1E-01

1E+00

1E+01

1E+02

1E+03

1E+04

1E+05

1E+06

1E+07

1E+08

1E+09

1E+10

1E+11

1E-02 1E-01 1E+00 1E+01 1E+02 1E+03 1E+04 1E+05 1E+06 1E+07 1E+08 1E+09 1E+10

Relative Intensity Of Light

CPS (Data ReadOut)

Dat

a Re

adou

t, P

ulse

s pe

r se

cond

[Cps

]

1S/s

Figure 2. Real Counting Mode Figure 3. Straight Output Mode

Diagrams of Typical Performance Characteristics3

Gigahertz Photon Detection Module

3

Figure 4. Fast Switching Mode Figure 5. HV Reduction Mode

PMT dynamic 1e7range

Range of MD electronics (DC)

1e4

Range of GPDM 1electronics

Figure 6. Dynamic Range Comparison CPM vs. PMT

GigaHertz Photon Detection ModuleMeasurement Bandwidth Extended Range / Fast Switching Mode at 1S/s

1E-01

1E+00

1E+01

1E+02

1E+03

1E+04

1E+05

1E+06

1E+07

1E+08

1E+09

1E+10

1E+11

1E-02 1E-01 1E+00 1E+01 1E+02 1E+03 1E+04 1E+05 1E+06 1E+07 1E+08 1E+09 1E+10

Relative Intensity Of Light

Dat

a Re

adou

t, P

ulse

s pe

r se

cond

[Cps

]

CPS (Data ReadOut)

GigaHertz Photon Detection ModuleMeasurement Bandwidth Extended Range / HV Reduction Mode at 1S/s

(example for gain set to 1/1000 of typ. gain)

1E-01

1E+00

1E+01

1E+02

1E+03

1E+04

1E+05

1E+06

1E+07

1E+08

1E+09

1E+10

1E+11

1E-02 1E-01 1E+00 1E+01 1E+02 1E+03 1E+04 1E+05 1E+06 1E+07 1E+08 1E+09 1E+10

Relative Intensity Of Light

Data Readout conv. to Pulses per second [Cps]

CPS (conv. Data Readout)

Dat

a Re

adou

t, P

ulse

s pe

r se

cond

[Cps

]

GigaHertz Photon Detection ModuleMeasurement Bandwidth Straight Output Mode at 1S/s

1E-01

1E+00

1E+01

1E+02

1E+03

1E+04

1E+05

1E+06

1E+07

1E+08

1E+09

1E+10

1E+11

1E-02 1E-01 1E+00 1E+01 1E+02 1E+03 1E+04 1E+05 1E+06 1E+07 1E+08 1E+09 1E+10

Relative Intensity Of Light

Dat

a Re

adou

t, P

ulse

s pe

r se

cond

[Cps

]

CPS (Data ReadOut)

WindowMaterial

UV glass

UV glass

UV glass

UV glass

UV glass

SpectralResponse/nm

185-650

185-850

185-900

185-650

185-750

Typ. dark countsper second (cps)

1040

100

100400

1000

5002000 5000

310 25

1040

100

PhotocathodeMaterial

Bialkali

Multialkali

Extended redMultialkali

Low noiseBialkali

ExtendedYellow

PhotocathodeDiameter/mm

5, 9, 15

5, 9, 15

5, 9, 15

5, 9, 15

5, 9, 15

InstalledCPM Type

C943 PC1343 P C1943 P

C963 PC1363 P C1963 P

C973 PC1373 P C1973 P

C983 PC1383 P C1983 P

C993 PC1393 P C1993 P

Model *(*also order no.)

GPDM 943GPDM1343GPDM1943

GPDM 963GPDM1363GPDM1963

GPDM 973GPDM1373GPDM1973

GPDM 983GPDM1383GPDM1983

GPDM 993GPDM1393GPDM1993

Page 4: Product Note Photon Detection Solutions...Gigahertz Photon Detection Module 3 Figure 4. Fast Switching Mode Figure 5. HV Reduction Mode PMT dynamic 1e7 range Range of MD electronics

Figure 7. Typical spectral response of C9xx CPM types. Identical characteristics for CPM types C13xx and C19xx

Spectral response

0.1

1

10

100

100 200 300 400 500 600 700 800 900

Wavelength (nm)

Qua

ntum

effi

cien

cy (%

)

C 911C 943/ 942

C 963/962

C 921

C 944

C 943

C 973

C 983

C 922

C 993/ 992

C 983/ 982

C 973/972

For a complete listing of our global offices, visit www.optoelectronics.perkinelmer.com

Copyright ©2009, PerkinElmer, Inc. All rights reserved. PerkinElmer® is a registered trademark of PerkinElmer, Inc. All other trademarks are the property of their respective owners. 008668A_01 Printed in Germany

PerkinElmer, Inc. 22001 Dumberry RoadVaudreuil, QC, Canada J7V 8P7T: (+1) 450-424-3300 (+1) 866-574-6786F: (+1) 450.424.3345Email: [email protected]

PerkinElmer, Inc.Wenzel-Jaksch-Str.3165199 Wiesbaden, GermanyT: (+49) 611.492.247F: (+49) 611.492.170Email: [email protected]

PerkinElmer, Inc.47 Ayer Rajah Crescent #06-12Singapore 139947T: (+65) 6775.2022F: (+65) 6775.1008Email: [email protected]

Typical Spectral Response4

Dimensions5

A

4.5

4.5

4.5

B

36

36

36

C

4.5

7

7

D

33

33

33

E

127

135

137

F

120

125

130

G

30

30

30

H

20

20

20

I

19.5

19

19

J

10

10

10

K

18

22.1

22.1

L

45

50

50

M

45

50

50

Module TypeDimension/mm

GPDM 9xx

GPDM13xx

GPDM19xx

Gigahertz Photon Detection Module