product portfolio overview - resources.rndsystems.com · product portfolio overview partnering with...

Product Portfolio OverviewPartnering with you to drive discovery

Over 3500 biologically active recombinant and natural proteins spanning 35 species. Quality•Stringentqualitycontrolspecificationsforactivity,purity,

and endotoxin. • More citations than any other protein manufacturer.• Lot-to-lot consistency.• Unmatched customer support.

Selection•Cytokines,receptors,proteases,andenzymesformetabolism

and glycobiology research. •Tagstomeetneeds:His,Fc,Biotin,Avi,andmore.•Morethan10,000non-catalogproteinsavailable.• ProDots®Proteins:Eliminatealiquotingusinglyophilizedspheres

that dissolve instantly in culture.

GMP Cytokines and Growth Factors•Madespecificallyforcell-basedclinicalmanufacturing•ISO9001,ISO13485-certifiedfacility.•Animal-freemanufacturing•Focusonconsistency,safety,andsupplychain• Global experience

Custom Development• Experience with a wide range of protein classes• New proteins from scratch• RUO to GMP conversion for ex vivo clinical manufacturing•Formulationtomeetyourrequirements• Dedicated project managers

PROTEINS

Learn more | rndsystems.com/proteins

Over4,000highqualitychemicaltoolcompounds. GPCRLigands,EnzymeInhibitors,IonChannelModulators,FluorescentProbes&Dyes,CompoundLibraries

• Competitive Pricing. Highendproductspricedtomaximizeyourresearchbudget.

• Be at the Forefront of Research. Fromthelatestexclusivelylicensedresearchtoolstoestablishedbiochemical standards.

• Unrivaled Product Quality. Certifiedhighpurity,typicallygreaterthan99%asmeasured by HPLC.

• Fully Annotated Compounds The biological activity of all products is supported by peer- reviewed publications.

SMALLMOLECULES

Learn more | tocris.com»

Over155,000antibodies.• Confidence in Your Purchase. Ourantibodiesare100%guaranteedtoworkintheapplication and species listed.

• Unique Clones and Exclusive Antibodies. ManyofouruniquecloneshavebeenusedbyHLDAtoestablishCDnomenclatureandweofferover15,000antibodiesthatareavailable exclusively from us.

• Wide Selection of Conjugated Antibodies. Weofferover50,000antibodiesconjugatedtoatleast14complimentary colors.

• Monoclonal Antibody Panels Thousands of non-catalog monoclonal antibodies available now. Testthesepanelsinyourapplicationtofindtheclonethatproduces optimal results.

• Recombinant Antibody Conversion and Engineering Services Wehavegeneratedhundredsofrecombinantantibodies,aslistedin our catalog. Let our experts convert your hybridoma to an immortalizedrecombinantantibodyandevenengineermodificationssuchasspecies,isotype,andFcregions.

• Custom Antibody Development Generatecustommonoclonalorpolyclonalantibodies,fromimmunogendesigntopurifiedantibodyspecificityscreening, by partnering with our expert development team.

ANTIBODIES

Learn more | rndsystems.com/antibodies novusbio.com»

Experts in developing tools for advancing stem cell and 3-D cell culture. • We Have You Covered Throughisolation,differentiation,verification,andinvestigation,wehavetoolstomakeyourstemcell,organoid,and3-Dcellculturemoreefficientandreliable.

• Minimize Experimental Variability Reducing experimental variability saves time and allows for more confidentdataanalysis.Fromstemcelldifferentiationandverificationkitstoadvancedtoolsfororganoidand3-Dtissuegeneration,ourportfoliohelpsresearchersbuildconsistentandrobust cell culture models.

• Don’t Wait to Differentiate Ourall-in-onekitsforthedifferentiationofES/iPScells,HSCs,MSCs,andNSCsmakeworkingwithstemcellslookeasy.

• Evolve Your 3-D Models Stay at the forefront of 3-D cell culture by using our organoid reagentguideortryingMimEX™TissueModelSystems,aninnovative technology for generating accessible 3-D epithelial tissue in vitro.

STEMCELLAND3-DCULTUREMODELS

Learn more | rndsystems.com/stemcells»

Expedite your research. Partnering with our industry-renowned product development and biomarker testing scientists to deliver unique reagents and reliable data.

• Custom Protein & Antibody Generation Our recombinant technologies provide gram quantities of consistent proteins and antibodies required for diagnostic and therapeutic reagent development.

• Assay Development R&DSystemshasover20yearsofexperiencedeveloping,optimizing,andvalidatingimmunoassaykitsandLuminex® assays to ensure the highest level of performance in analytequantification.

• Biomarker & Bioactivity Testing Services Entrusting our experts with your clinical study samples ensures accurateresultsthatarereturnedinatimely,efficient,regulatorycompliant,andconfidentialmanner.

CUSTOMPRODUCTS&CONTRACTSERVICES

Learn more | rndsystems.com/custom»

CELLCULTUREESSENTIALS

Growhealthyandrobustcellswithourfullcellcultureworkflowportfolio.• Culture with Confidence Fromcellculturesubstratesandmediasupplementstodifferentiationandcellbehaviorkits,ourtoolsforcellculturearedesigned to ensure that in vitro and ex vivo experiments will perform optimally.

• Cell Culture Basics by the Best Withtheadditionofhigh-qualityAtlantaBiologicals™FetalBovineSerum,animalserum,basemedia,andbalancedsaltsolutionsitiseasierthaneverforresearcherstogeneratemediaoptimized for their cell of choice.

• Optimized Kits and Media Supplements Withhigh-qualitygrowthfactors,cytokines,smallmolecules,andmatrixcomponentsatourdisposal,we’vedesignedspecialtymediaandkitsforthegrowthanddifferentiationofimmunecells,braincells,stemcells,andmore.

Learn more | rndsystems.com/cellculture»

Ubiquitin RelatedDiscovery ToolsInhibitors

KitsDUBs

Ubiquitin and Ubiquitin-like Modifiers

Animal-Free™

ProDots™ ProteinsGMP-Grade

High Bioactivity

Custom ProteinDevelopment

High Purity

Cell Differentiation Kits

Lot-to-Lot ConsistencyBulk AvailableProteins

Largest Offering of Bioactive Proteins

Surveyor™ ICImmunoassays

Parameter™ Kits

ELISpot

Fluorokine® E Activity Assay

Cell-Based ELISAs

Quantikine® HS

Quantikine® IVD

QuantiGlo®

DuoSet® Kits

Quantikine® ELISAs

DuoSet® IC Kits

DevelopmentModules

Complete Kits

ELISAsSetting the Industry

Gold Standard

RNAscope® Probes

Reagent Kits

Software & Quality Controls

Hybridization Systems

RNA ISHDetect Biomarkers

with Precision

Receptor Agonistsand Antagonists

Enzyme Inhibitors

Caged Compounds

Fluorescent Probes

Peptides

Compound Libraries

Ion Channel Modulators

Small MoleculesHigh Performance

Life Science Reagents

Growth Factors

Small Molecules

Gastrointestinal

Airway

Liver SkinCell ScaffoldingMatrices

N21-MAX and N-2 Supplements

Organoids

MimEX™ Tissue Model Systems

Mesenchymal

Hematopoietic

Neural

Differentiation Kits

Pluripotency Verification Kits

iMEF Cells

ES/iPS Cells

Stem Cells &3-D Models

Culture. Differentiate.Verify. Investigate.

FLEXMAP™ 3DLuminex®

MAGPIX™

Luminex 200™

Peggy Sue

Simple Western

SimplePlex

ProteinSimple®

Wes™

EllaMilo™

Maurice™

Micro-FlowImaging

FluorChemImagers andAlphaImagers

Sally Sue

InstrumentsInnovative Multi-analyte

Detection Platforms

SecondaryAntibodies

ISO Controls

ApplicationValidation

Conjugated

NorthernLights™

MultipleFluorochromes

Biotin

WB

ELISA

B/N

Simple Western™

IHC/ICC

IF

CD

FCChIP

IP

AP

AntibodiesOver 155,000 Available

Media Supplements

Cell Behavior Assays

Migration

Invasion

ProliferationApoptosis

DNA Damage

Fetal Bovine Serum

Balanced Salt Solutions

Atlanta Biologicals™ by R&D Systems

Antibiotics/Antimycotics

Cultrex® ECM and Basement Membrane Extracts

Cytokines

Growth FactorsSpecialty Media

Base Media

Grow Healthy & Robust Cells

Cell CultureEssentials

Luminex Assay Performance

Measure 100 AnalytesSimultaneously

Magnetic and Polystyrene Beads

Most Flexible Most Accurate

ConfigureYour Panel

Luminex®

Assays

Zebrafish

MultipleSpecies

Mouse

Human

Canine

Viral

Drosophila

Feline

Porcine

Rat

Bovine

No SpecializedEquipment Needed

Proteome Profiler™

More than 100 Analytes at Once

Membrane-Based

ProteomeProfiler™ ArraysEach Analyte Extensively

Tested for Specificity

Single Cell Western Lateral FlowKnockout/Knockdown ValidatedCyTOF-ready

Choose from Standard or High Performance• High Perfomance. LuminexHighPerformanceAssaysarethemostaccurateandprecise bead-based multiplex assays for simultaneously measuring upto45analytesfromcustomizablepanelsinqualifiedcomplexmatrices. You choose if you prefer us to mix the beads or if you want to do it yourself.

• Uniquely Flexible Assay Options. OurStandardLuminexAssaysaretheonlyassaysonthemarketina premixed format where you choose from a large selection of analytes to create your own unique panel of 50 analytes which are then fully quality controlled for compatibility before shipment.

• Results You Can Trust. We are the immunoassay experts with 30 years of experience using our internally manufactured antibodies in developing assay conditions and diluents to protect against false positives.

• Complete Your Panel of Analytes. Take advantage of our massive in-house collection of antibodies and proteins. Complete your panel with a custom development order.

LUMINEX®ASSAYS

Learn more | rndsystems.com/luminex»

700analytesspanning12species.• Legendary Performance.

Quantikine®ELISAkitssettheindustrygoldstandardinperformance and reproducibility. Results today can be compared to last month or even last year.

• Confidence with Controls. Our assays have available controls with assigned ranges which guarantee performance.

• Economical Alternatives. Our DuoSet® and DuoSet®Intracellular(IC)ELISADevelopmentSystems provide the best signal-to-noise ratio for value- conscious labs.

We outperform the competition. • Be Confident in the Data. Small,crispspotsallforeasiermoreaccuratequantitationand the largest dynamic range (number of detectable spots/well) on the market.

• Detect Low Frequency Responses. Our kits can measure responses with frequencies well below 1 in 100,000cells–upto20%moresensitivethanourcompetition.

• Be Assured the Kit Worked. We are the only company that provides recombinant protein positive controls.

ELISAs ELISpot

Learn more | rndsystems.com/elispotLearn more | rndsystems.com/elisas» »

Cast a wide net and stretch your dollar.• Can You Run a Western Blot? Iftheanswerisyes,thenyouhavealltheequipmentyouneedtouse our antibody arrays.

• User-Friendly Design. Eacharrayisstampedwithanidentificationnumberforeasyrecordkeeping and contains reference spots in three corners for orientation purposes.

• Cost-Effective Screening. Each array offers a quick and inexpensive analysis of many analytessimultaneously,inlesstimethanittakestoperformaWestern blot.

ANTIBODYARRAYS

Learn more | rndsystems.com/proteomeprofiler»

Luminex®

MAGPIX® System•Simple,compact,affordable,andabletomultiplexupto50analytesusingmagneticbeads

with a read time of just 60 minutes for a 96-well plate.

Luminex® 200™

•Multiplexupto100analytesusingpolystyrenebeadsor80analytesusingmagneticbeadswithareadtimeofonly45minutesfora96-wellplate.

FLEXMAP 3D® •Themostadvancedandversatilemultiplexingplatform.Compatiblewith96-and384-wellplates,itreadsupto500beadregionsinboththepolystyreneandmagneticformatsandis compatible with front-end automation systems making this the ideal platform for high-throughput applications.

INSTRUMENTATION

ProteinSimple®

Ella runs Simple Plex™ assays.•Runupto4immunoassaysfrom25uLofsample,withnocross-reactivity.

•Setupsamplesin10minutes,getdatain1hour.

•Gethighlysensitiveresultsat<10%CV.

•Choosefromupto150validatedtargets,fromcytokinestoPD-L1.

Wes™, Peggy Sue™ and Sally Sue™ run Simple Western™ assays.•Separationbycapillaryelectrophoresisandimmunodetectionofproteinsfrom2–440kDaorbycharge(IEF).

•Nogel,blotsandminimalhands-onarerequired.

• Sample to results in as little as 3 hours with Wes.

•Quantifiableandreproducibledata.

Milo™

•MilodoesSingle-CellWesternstomeasureproteinexpressionin~1,000singlecellsinasingle run.

•Multiplextomeasure~4proteinsineachsingle-cell.

•Useoff-the-shelf,Western-validatedantibodiestomeasureintracellularproteinsortargetsthatdon'thavegoodflowantibodies.

•Identifycellsubtypesthataren’tvisibleintraditionalWesternsorgetdirectproteinvalidationofyoursingle-cellRNAresults.

Maurice• Next generation analytical platform for protein-based biopharmaceutical products.

•cIEForCE-SDSdatainasnap.

•NovelnativefluorescencedetectionprovidesincreasedcIEFsensitivity.

• Proprietary ready-to-use cartridge for unparalleled ease-of-use.

Micro-Flow Imaging™ (MFI)• Image based analysis for sub-visible particles.

• Highly sensitive detection for translucent particles.

• Morphological measurements to distinguish different particle populations.

• Walk-away automation for up to 90 samples.

FluorChem™ Imagers and AlphaImagers. •Highqualitydigitalimagingandanalysisforprotein/DNAgelsandWesternblots.

•Coverawiderangeofapplications,fromcolonycountingtomulticolorfluorescentWesterns.

•Easy-to-use,versatilesystemswithpowerfulanalysissoftware.

• Numerous excitation and emission options.

Luminex®MAGPIX™

Luminex®200™

Luminex®FLEXMAP™

MiloTM

iCEsystems:ImagedcIEF&CE-SDS

Ella

WesTM

R&D Systems develops and manufactures high-quality proteins andservesasaworldleaderinimmunoassays.R&DSystemsalsoproducesqualityantibodies,antibodyarrays,stemcellandcellcultureproducts,andcellselectionanddetectionproducts,servingthe life science and diagnostics industry. rndsystems.com

Novus Biologicals licenses,manufactures,andmarketsantibodiestoover20,000uniquetargetstosupportawidearrayofresearchareas.Novusisbuiltonhonesty,collaborationandstrongrelationships and continues to provide quality tools that accelerate research.Everyproductisbackedbyour100%guarantee. novusbio.com.

Tocris Bioscience is a leading supplier of innovative high performance life science research reagents. The Tocris range of small molecules and peptides represents a unique collection of novel andexclusiveresearchtools,includingGPCRligands,ionchannelmodulators,enzymeinhibitors,cagedcompounds,fluorescentprobes,andscreeninglibraries. tocris.com

ProteinSimple AtProteinSimplewe’rechangingthewayresearchersanalyzeproteins.Ourinnovativeproductportfoliohelpsresearchersrevealnewinsightintoproteins,advancingtheir understanding of protein function. We enable cutting-edge research to uncover the role of proteins in disease and provide novel approachestodevelopandanalyzeprotein-basedtherapeutics.Weempower you to make your next discovery by eliminating common proteinanalysisworkflowchallenges. proteinsimple.com

Advanced Cell Diagnostics (ACD) enables single day manual and automated gene expression analysis by providing optimizedsingeandmultiplexchromogenicandfluorescenceassaykits,>15,000off-the-shelftargetprobesandpharmaassayservicesbasedonRNAscope®technology,themostadvancedRNAin situ hybridization(ISH)assaywhichallowsresearcherstovisualizegenesexpressedatasinglemoleculeRNAsensitivity,localizewheretheyareexpressed,andquantifythelevelofexpression.Enablingacademicresearch,drugdevelopment,diagnosticandCDxassays,ACD’scoreapplicationsincludecancer,immune-oncology,neuroscience,Infectiousdisease,stemcellresearchandgenetherapy.RNAscopehasreached1000peerreviewedpublicationsinless than 6 years. acdbio.com

BR_ProductPortfolio_31509

[email protected]/find-us/distributorsTEL+16123792956North AmericaTEL8003437475Europe | Middle East | AfricaTEL+44(0)[email protected]+86(21)52380373

bio-techne.com

RnDSy-2945 Novus-2945 Tocri-2945

Prote_2945

Forresearchuseormanufacturingpurposesonly.Trademarksandregisteredtrademarksarethepropertyoftheirrespectiveowners.

product portfolio overview - resources.rndsystems.com · product portfolio overview partnering with...

Documents