Project Overview

Jörg Freund, SiemensDavid Manset, MaatGKnowledge

HG09, 29-Jun-09, Berlin

2 Health-e-Child Jörg Freund, David Manset, 29th June 2009, HG09, Berlin

Health-e-Child at a Glance

Establish multi-site, vertical, and longitudinal integration of data, information and knowledge

Develop a GRID based platform, supported by robust search, optimisation and matching

Build enabling tools and services that improve patient care

Two main use case scenarios•“Aiding the Clinician in Decision Making”•“Clinical Studies”

Healthy Child

Dec

isio

n S

uppo

rt S

yste

ms

Integrated Disease Modeling

Know

ledge Discovery

Augment

GuidanceGuidanceEnrich

Real-time alert

On-line learning

Ob

se

rva

tio

n P

roc

es

sS

en

so

rs

Imaging

Genomics

Lab Data

Proteomics

Demographics

Physician Notes

Life Style

Time

Organ

Tissue

Cell

Molecule

Population

Individual

Ver

tica

l D

ata

Inte

gra

tio

n

Integrated Medical

Database

3 Health-e-Child Jörg Freund, David Manset, 29th June 2009, HG09, Berlin

Health-e-Child Platform Overview

Gateway

Grid – EGEE gLite

IGG

Ontological Layer Query ProcessingData

Management

Cardiology Right Ventricular Overload

Cardiomyopathy

RheumatologyJuvenile Idiopathic

Arthritis

NeuroOncologyBrain Tumors / Gliomas

Knowledge Discovery

Decision Support Systems

Disease Models

4 Health-e-Child Jörg Freund, David Manset, 29th June 2009, HG09, Berlin

4 paediatric hospitals IGG - Gaslini, Genoa, Italy

GOSH, London, UK

NECKER, Paris, France

OPBG, Rome, Italy

Strong interdisciplinary team across Countries and languages Technical and clinical fields

Research on three paediatric areas Arthritis Cardiac Disorders Brain Tumours

Health-e-Child Network Year 3

• 7 technical sites• 4 clinical sites

(1 currently under deployment finalisation)

5 Health-e-Child Jörg Freund, David Manset, 29th June 2009, HG09, Berlin

Overview

ICD

Cardiology RheumatologyNeuroOncologyA

uth

3D

Bro

wse

r

MD

Ma

n

Heatmap

Pa

t. B

row

ser

Da

ta A

cqC

ase

Re

aso

ne

r

AIT

ION

Tre

em

ap

s

SOFA

JIAnnotate

CardioViz3D

3DRegTool

RADBuilder

Au

tom

ato

rG

ridO

S

6 Health-e-Child Jörg Freund, David Manset, 29th June 2009, HG09, Berlin

Virtual Physiological

Child

Decision Support

DISEASE MODELS

GRID INFRASTRUCTUREDATA INTEGRATION

MEDICAL DSS

7 Health-e-Child Jörg Freund, David Manset, 29th June 2009, HG09, Berlin

Knowledge Discovery

DISEASE MODELS

GRID INFRASTRUCTUREDATA INTEGRATION

MEDICAL KD

Virtual Physiological

Children

8 Health-e-Child Jörg Freund, David Manset, 29th June 2009, HG09, Berlin

Pediatrics Knowledge Applications

DECISION SUPPORT KNOWLEDGE DISCOVERY

9 Health-e-Child Jörg Freund, David Manset, 29th June 2009, HG09, Berlin

Dem

onst

ratio

nHealth-e-Child Demonstrator

Integrated Demonstr

ator

Domains• Cardiology• Rheumatology• Oncology

Sites• Gaslini, Italy• Necker, France• GOSH, UK

Scenarios• Personalized

Decision support• Similarity Search

• Knowledge Discovery

IT Innovation• Machine Learning• Imaging• Data Integration• Grid• ...

+++

10 Health-e-Child Jörg Freund, David Manset, 29th June 2009, HG09, Berlin

Collaboration with @neurIST

(3DKnowl. + @neuLINK)

External Collaborations

Network and Collaboration expansion to the US

11 Health-e-Child Jörg Freund, David Manset, 29th June 2009, HG09, Berlin

12 Health-e-Child Jörg Freund, David Manset, 29th June 2009, HG09, Berlin

EuroNews TV documentary

• http://www.euronews.net/2009/06/17/new-frontiers-of-imaging-the-human-body/