prospective urban and rural epidemiology study pure
DESCRIPTION
Prospective Urban and Rural Epidemiology Study PURE. Patricio López-Jaramillo, MD, PhD Lina Patricia Pradilla MD National Coordinator Colombia. PURE - URBAN. Bucaramanga 300 subjects Sampling by blocks All economical social levels representated 01 1XX XXX 01. PURE - RURAL. - PowerPoint PPT PresentationTRANSCRIPT
Prospective Urban and Rural Epidemiology Study
PURE
Patricio López-Jaramillo, MD, PhD
Lina Patricia Pradilla MD
National Coordinator
Colombia
PURE - URBAN
Bucaramanga• 300 subjects• Sampling by blocks• All economical social
levels representated• 01 1XX XXX 01
PURE - RURAL
• 317 subjects• Included three areas:
– Aratoca (01 2XX)– Barichara (01 3XX)– Villanueva (01 4XX)
STATUS OF COLOMBIAApplied Surveys
URBAN RURAL
MEN 93 126
WOMEN 242 191
NON-RESPONDER
20 0
TOTAL 355 317
STATUS OF COLOMBIA
Examinated population
URBAN RURAL
MEN 87 126
WOMEN 213 191
TOTAL 300 317
MALEUrban (n=87) Rural (n=126)
pMean SD Mean SD
Age 51.8 9.3 50 10 NS
Systolic BP 131.0 17.4 133.4 18.4 NS
Diastolic BP 82.4 10.9 82.5 10.8 NS
Weight 75.8 11.2 67.6 10.9 <0.001
Height 167.8 6.3 167.8 6.48 NS
BMI 26.8 3.3 24 3.7 <0.001
Waist 90.2 9.3 85.6 9.97 0.0001
Hip 97.1 6.9 91.7 8.2 <0.001
W/H ratio 0.92 0.06 0.93 0.09 NS
Glycemia 98.6 21.6 85.6 16.5 <0.0001
FEMALEUrban (n=213) Rural (n=191)
pMean SD Mean SD
Age 51.0 9.8 49.9 9.5 NS
Systolic BP 128.1 23.0 134.2 22.2 0.0019
Diastolic BP 79.9 11.0 83.4 12.7 0.0032
Weight 65.7 13.0 60.5 10.6 0.0001
Height 154.1 6.3 154.2 6 NS
BMI 27.7 5.5 25.4 4.2 <0.0001
Waist 81.0 11.5 80.7 10.3 NS
Hip 99.5 9.8 95.2 9.2 <0.0001
W/H ratio 0.81 0.07 0.84 0.07 <0.0001
Glycemia 96.7 20.2 87.6 19.6 <0.0001
MALE
Urban (n=87) Rural (n=126)p
Mean SD Mean SD
Arm 30.9 2.8 27.5 3 <0.0001
Calf 36.6 3.3 35.2 3.2 0.0016
Head 56.1 1.6 55.2 2 0.0001
Grip Strenght
36.1 7.7 34.4 7.5 NS
FEMALE
Urban (n=87) Rural (n=126)p
Mean SD Mean SD
Arm 30.4 4.3 27.3 3.1 <0.0001
Calf 35.5 3.5 34.2 3.8 0.0009
Head 54 1.3 53.4 1.8 0.0001
Grip Strenght
22.3 4.9 24.3 5.1 0.0001
Prevalence Blood Pressure ≥135 / ≥85
Total Urban Rural p
Total sample (%)
276 (44.7)
124 (44.9)
152 (55.0)
0.0913
Men (%)
108 (50.9)
45 (41.6)
63 (58.3)
0.8495
Women (%)
168 (41.5)
79 (47.0)
89 (52.9)
0.0529
p value: Х2 test urban vs rural
Prevalence Obesity Body Mass Index > 30Kg/m2
Total Urban Rural p
Total sample (%)
101 (16.3)
71 (70.2)
30 (29.7)
<0.0001
Men (%)
24 (11.2)
16 (66.6)
8 (33.3)
0.0063
Women (%)
77 (19.0)
55 (71.4)
22 (28.5)
0.0003
p value: Х2 test urban vs rural
Prevalence Abdominal Obesity Waist Circumference
Total Urban Rural p
Men* (%)
78 (36.7)
45 (57.6)
33 (42.3)
<0.0001
Women** (%)
192 (47.5)
103 (53.6)
89 (46.3)
0.724
* Men: Waist circumference ≥ 90 cm
**Women: Waist circumference ≥ 80 cm
p value: Х2 test urban vs rural
Prevalence of Fasting plasma glucose >100 mg/dl
Total Urban Rural p
Total sample (%)
121 (19.6)
89 (73.5)
32 (26.4)
<0.0001
IFG (%)93
(15.0)69
(74.1)24
(25.8)<0.0001
Type 2 DM(%)
28 (4.0)
20 (71.4)
8 (28.5)
0.0135
p value: Х2 test urban vs rural
Impaired Fasting Glucose
Total Urban Rural p
Male (%) 27 (12.6) 15 (74.0) 7 (25.9) 0.0002
Female (%) 66 (16.3) 49 (74.2) 17 (25.7) 0.0001
Type 2 Diabetes Mellitus
Male (%) 7 (3.2) 5 (71.4) 2 (28.5) 0.0942
Female (%) 21 (5.2) 15 (71.4) 6 (28.5) 0.0778
p value: Х2 test urban vs rural
LESSONS LEARNED
• Urban: 1 month to complete all study in 300 subjects
• Rural: 1.5 month
• Personal: six ( 2 MDs, 3 nurses, 1 laboratory technician, all full time)
