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Purina OAMMlL Nutrition News FEEDING LABORATORY RATS By H. C. Schaefer, Director Purina Laboratory Chow Research Rats have made a tremendous contribution to the science of nutrition. They are indispensable for the assay of certain vitamins and the biological assay of other nutrients. The nutrient requirements of laboratory rats are probably better known than those of any other animal used in research. Much of the fundamental information on amino acids, vitamins; and minerals was learned from investigations with rats. Purina Laboratory Chow was an outgrowth of this discovery. We recommend Purina Laboratory Chow as the sole ration for laboratory rats without any supplements. It is an excellent and economical diet for reproduction, lactation and growth. Since the use of diethylstilbestrol in cattle fattening rations, Purina Laboratory Chow is made at one of our mills where no estrogens are used. As an extra precaution, Laboratory Chow is being biologically assayed to make sure it contains no estrogenic activity. This is of special significance to investigators in the endocrine and cancer fields. Laboratory Chow can be obtained in several different forms for the convenience of the investigator. The Checker form makes for easy and economical feeding. The meal form is a convenience for drug assays or oral administration for toxicology studies. For further information about the nutrient content of Purina Laboratory Chow, please see your local Purina Dealer or write to Special In dustry Sales, Ralston Purina Company, St. Louis 2, Missouri. WITH OVER 5,000 DEALERS COAST TO COAST TO SERVE YOU * - v o

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Page 1: Purina OAMMlL Nutrition - Sciencescience.sciencemag.org/content/sci/122/3166/local/front-matter.pdf · Purina OAMMlL Nutrition News FEEDING LABORATORY RATS ByH. C. Schaefer, Director

Purina OAMMlL Nutrition News

FEEDING LABORATORY RATSBy H. C. Schaefer, Director Purina Laboratory Chow ResearchRats have made a tremendous contribution to the science ofnutrition. They are indispensable for the assay of certainvitamins and the biological assay of other nutrients.The nutrient requirements of laboratory rats are probablybetter known than those of any other animal used in research.Much of the fundamental information on amino acids, vitamins;and minerals was learned from investigations with rats.Purina Laboratory Chow was an outgrowth of this discovery.We recommend Purina Laboratory Chow as the sole ration forlaboratory rats without any supplements. It is an excellentand economical diet for reproduction, lactation and growth.Since the use of diethylstilbestrol in cattle fattening rations,Purina Laboratory Chow is made at one of our mills whereno estrogens are used. As an extra precaution, LaboratoryChow is being biologically assayed to make sure it containsno estrogenic activity. This is of special significance toinvestigators in the endocrine and cancer fields.Laboratory Chow can be obtained in several different formsfor the convenience of the investigator. The Checker formmakes for easy and economical feeding. The meal form isa convenience for drug assays or oral administration fortoxicology studies.For further information about the nutrient content of PurinaLaboratory Chow, please see your local Purina Dealer orwrite to Special Industry Sales, Ralston Purina Company,St. Louis 2, Missouri.

WITH OVER 5,000 DEALERS COAST TO COASTTO SERVE YOU

* - vo

Page 2: Purina OAMMlL Nutrition - Sciencescience.sciencemag.org/content/sci/122/3166/local/front-matter.pdf · Purina OAMMlL Nutrition News FEEDING LABORATORY RATS ByH. C. Schaefer, Director

New (4th) Edition

Marshall-Lazier

Human Anatomy ll

Here is a beautifully illustrated text for an elementary oBo cks

course in human anatomy. Form and function of thehuman body and the relationship of one part to anotherare explained with unusual clarity.

For the New (4th) Edition special attention has been given to the treatment of the neuro-

sensory system. The organs of common sensation have been combined with the chapter on

the nervous system. The section on the Endocrine System has also been completely re-

written. 25 new illustrations have been added.

More than usual emphasis is placed on the joints and segments. Muscles are described as

functional groups, simplifying the task of the student, and making it easier for him to

remember.

By CLYDE MARSHALL, M.D., Formerly Assistant Professor of Anatomy, Yale University. Revised by EDGAR L. LAZIER,Ph.D., Professor of Zoology, University of California at Los Angeles. 420 pages, 5'/2" x 8'!1", with 329 illustrations.

New (4th) Edition!

Frobisher -Microbiology

This text furnishes a firm foundation in the fundamentals of microbiology for the

beginning student. Part I introduces the student to the 8 groups of microorganisms,describing their size, structure and activities.

Part II presents microscopic methods with full details on how one studies microorgan-isms in the laboratory, how they grow, their biochemical and physiologic aspects.

Immunology is covered in Part III and antigen-antibody reactions discussed. With bac-

teria as the basis, Part IV discusses such biological phenomena as evolution, autotrophy,heterotrophy, photosynthesis, chemosynthesis, ecology of microorganisms, etc. The fifth

and final part pictures the special environments in which microorganisms occur.

By MARTIN FROBISHER, JR., Sc.D., Special Consultant, Bscteriology Branch, Communicable Disease Center, U.S.Public Health Service, Chamblee, Georgia; Associate Professor of Bacteriology, Emory University; Visiting Lecturer,Johns Hopkins School of Hygiene and Public Health. 633 pages, 6" x 9¼/4", with 253 illustrations. $6.00.

Fifth Edition!

W. B. SAUNIDERS COMPANY

West Washington Square Philadelphia 5

SCIENCE is published weekly by the AAAS, 1515 Massachusetts Ave., NW, Washington 5, D. C. Entered at the Lancaster, Pa., Post Office as second classmatter under the act of 3 March 1879. Annual subscriptions: $7.50; foreign postage, $1; Canadian postage, 50g.

2 SEPT9EMBER 1955 395

Page 3: Purina OAMMlL Nutrition - Sciencescience.sciencemag.org/content/sci/122/3166/local/front-matter.pdf · Purina OAMMlL Nutrition News FEEDING LABORATORY RATS ByH. C. Schaefer, Director

396 SCIENCE, VOL. 122

Page 4: Purina OAMMlL Nutrition - Sciencescience.sciencemag.org/content/sci/122/3166/local/front-matter.pdf · Purina OAMMlL Nutrition News FEEDING LABORATORY RATS ByH. C. Schaefer, Director

aIprecision instruments

for industrial andscientific laboratories

STEREOSCOPICmicroscopes

remarkable clarity and depthLeitz STEREOSCOPIC Microscopes provide a truly three-dimensional imdge of unsurpassed brilliance for examinationsin the industrial and sciertific laborotory. They are engineeredto give precision performance-assembly work on small parts,quality control, examinations in geology, mineralogy and inthe biological field.* Wide field of view * Dual controls * Polarized, transmitted or

incident light * Interpupillary adjustment - Inclined eyepiecesfor comfort - Magnification ranges from 16 to 216X - Superior

L image quality through unique prism arrangement

HEATINGmicroscopes

prec determination of melting behavior

Simplified, accurate determination of the melting behavior offuel ashes, slogs, glazes, enamels, glass and ceramics is as-sured with the Leitz HEATING Microscope, which permits visualobservation and photographic recording of softening and melt-ing phases. A series of photographs and temperature registra--tions provide laboratory evidence from which the viscosity ofthe specimen may be determined. Accessories avoiloble forincident light examination. Polarized light accessories avail-ebb for strain ond stress analysis under high temperature used

for control of bondage between glass (or ceramics)1Ro retal¢.^,-., ;...............

E. LEITZ, INC., Dept. SC-9468 Fourth Ave., New York 16, N. Y.

Please send me additional information on theD STEREOSCOPIC Microscope D HEATING Microscope

City Zone State_

09155

E. LEITZ, INC., 468 FOURTH AVENUE, NEW YORK 16, N. Y.

Distributors of the world-famous products of Ernst Leitz, Wetzlar, GermanyLENS ES * CAM ERAS * MICROSCOPES * BINOCULARS

2 SEI'TEMBER 1955

INU F" t:

btreet

397

Page 5: Purina OAMMlL Nutrition - Sciencescience.sciencemag.org/content/sci/122/3166/local/front-matter.pdf · Purina OAMMlL Nutrition News FEEDING LABORATORY RATS ByH. C. Schaefer, Director

New KodagraphMicroprint Reader makes

them a pleasure to read

The microprint idea can reduce the largest li-brary to a small set of cards. Sixty conventionalpages can go on a 3 x 5-inch card, with an ab-stract and filing data in ordinary-size type on

the other side.The Kodagraph Microprint Reader lets you

read in complete comfort. The screen is greenand tilted 110 because that's the combinationthat seems to be easiest on the eyes. It's brightenough to use in ordinary room light. Severalpeople can read at a time.You feed microprint cards into a Kodagraph

Microprint Reader like paper into a typewriter-any size up to 812 x 14 inches.Many publishers offer microprint card edi-

tions. Many are also prepared to make micro-print cards for you from your own literatureand reports.To get started on a microprint system that can

help solve the problems of debulking, speedy dis-semination, and storage of literature and privateinternal data, mail the coupon below.

EASTMAN KODAK COMPANY 65

Business Photo Methods Division, Rochester 4, N. Y.

Please send me the information checked:

| Where I can see a Kodagraph Micropriti Re?ader.CD Folder on the Reader and sample micraprint card.

EJ List of publishers of microprint cards ar.J manufacturersof microprint cards to order.

NAME -- j

* Iron Hypophosphite

* Iron lodate* Iron Iodide* Iron Oleate* Iron Salicylate* Iron Selenide* Iron Tetracarbonyl,

cryst.

* Isoarachidic Acid* Isobehenic Acid

* Isocapric Acid

* Isocerotic Acid

* Isochrysene* Isodurene* Isolauric Acid* Isolignoceric Acid

'Bh

* Isomyristic Acid* Isonicotinic Acid

Hydrazide

* Isopalmitic Acid

* Isoprene Sulfone* Isopropylhydrazine

Sulfate* Isoquercitrin

* Isoriboflavin

* Isostearic Acid

* Juglone* Kaempferol* Keratin* Ketene Dimer* x-Keto-b-aminovaleric

acid

Ask for our newcomplete catalogue

GENERAL BIOLOGYM ICROSCOPES

FUNCTIONALLY DESIGNEDWITH SAFETY IN MIND

MIODEL GB2 All metail constructionA full fine adjustment with

12 revolutionsPlano-concave mirror that

can't fall out

An elongated base to pro-tect optics

Achromatic objectives16 mm (lOX) N.A. 0.274 mm (44X) N.A. 0.66

Huyghenian ocular (lOX)

List $118.00

5 or more. $106.20each

Old instruimentsaccepted in trade

THE GRAF-APSCO CO.5868 BROADWAY CHICAGO 40, ILL.

398

ADDURtE

>SSCIEN'CE, VOL. 1"22

Page 6: Purina OAMMlL Nutrition - Sciencescience.sciencemag.org/content/sci/122/3166/local/front-matter.pdf · Purina OAMMlL Nutrition News FEEDING LABORATORY RATS ByH. C. Schaefer, Director

EASIEST

BAUSCH & LOMB

EVE!

MICRO-PROJECTOR

Projects vivid true-colorscreen images for a solid hourwithout interruption!

just flick the lever for instantchoice of screen magnifica-tions from 20 X to 3000 X (at12 feet). You get the right light... autonzatically ... because when youselect an objective its matched condensermoves into perfect alignment. Screen images arebright and clear, critically detailed. Automatic elec-tronic-feed arc lamp assures uniformly intense lightfor 60 minutes of uninterrupted viewing-you con-centrate on the screen, not on the instrument. Effi-cient heat-control system eliminates need for color-distorting coolants . . . assures true-color images.Complete, SI 195.

Basic Illuminating Stand can be used, as shownhere, with any microscope which has a substagecondenser. Completewith built-in clamp-ing device, built-infixed mirror, Balcot-ed projection eye-piece, prism andlight shield, $376.

See for yourself inFREE DEMONSTRATION !WRITE today for your free demonstration and for yourcopy of informative Catalog D-246. Bausch & Lomb Opti-cal Company, 64273 St. Paul St., Rochester 2, New York.

America's only complete optical source ... from glass to finished product.

SCIENCE. VOL. 122400

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