pyrethrum and synthetic pyrethroids
DESCRIPTION
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INTRODUCTION
WHAT IS PYRETHRUM?
PROPERTIES
Ecofriendly Quick action Low toxicity Multipurpose √ Repellant √ Flushing agent No development of insect immunity
MECHANISM OF ACTION
METHOD OF APPLICATION
Space spray Kills adult mosquitoes & other insects 0.5 – 1 oz of solution/1000 cu ft of
space After spraying windows & doors
should be closed for not less than 30 mins
SYNERGESTIC EFFECT??
Pyrethrum + DDT or Piperonyl (low toxicity) butoxide
Common formulation of PYRETHRIN (Enhanced toxicity)
SYNTHETIC PYRETHROIDS
Replace the natural pyrethrins 10 times more effective Examples:
1) Lambda cyhalothrin(cyano group)
2) Permethrin3) Tetramethrin4) Rosethrin
5) Proparthin
MECHANISM OF ACTION
Affect CNS Prolong deactivation of
voltage gated Na channel
Prolonged excitation of fibres Lambda cyhalothrin-more neurotoxic
-more selectivity
SIDE EFFECTS
PYRETHROIDS Inhalation- coughing,wheezing,shortness
of breath Skin- itching,rash,paraesthesia(lamda
cyhalothrin) Neurotoxic effect-tremor, incoordination,
increased body temp Long term effects-disrupt endocrine
system -carcinogen(thyroid gland)
PIPERONYL BUTOXIDE
Skin ulceration
Eye irritation
Long term-carcinogen
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