Quality of life in patients with implantable cardioverter

defibrillators

Author: Camelia Tănăsuc

Coordinator: Professor Doctor Dan Dobreanu

Coauthors: Diana Costaș,Ioana Șuș,Roxana Rudzik

Objective

• the aim of this study was to assess quality

of life (QOL) in relationship to clinical data

in patients with implanted ICD

Material and Method

The Medical Outcome Trust

Short Form (SF-12v2) Health

Survey

Clinical data

• age

• myocardial infarction

• heart failure

Results

PSSphysical status

score

MSSmental status

score

mean±SD baseline

41±9.69 50±12.78

median 40.5 48

‘Low’ PSS group:

• 8 patients ;

• PSS score ≤40.5;

• older (51± 8.35 vs 46± 21.69) ;

• severe heart failure ;

• myocardial infarction ;

• MSS score also lower (45±14.83 vs 54±10.10) .

‘Low’ MSS group:

• 8 patients ;

• MSS score ≤48 ;

• older (53±13.72 vs 44±17.96) ;

• severe heart failure ;

• myocardial infarction ;

• PSS was lower (39± 8.91 vs 60± 5.99,

p= 0.00006) .

Discussions

• except PSS between ‘low’ and ‘high’ MSS group, the differences are not statistically significant.

• the type and number of ICD therapies do not appear to influence any PSS or MSS.

Discussions

• Piotrowicz et al.¹ found that ‘low’MSS or PSS group have severe heart failure, NYHA II- IV, but were younger.

• neither PSS nor MSS was significantly associated with ICD-therapy.

1. Katarzyna Piotrowicz, Katia Noyes, Jeffrey M. Lyness, Physical functioning and mental well-being in association with health outcome in patients enrolled in the Multicenter Automatic Defibrillator Implantation Trial II. European Heart Journal (2007) 28, 601–607

Discussions

• Schron et al.² showed that any kind of shock, compared with receiving no shocks, is associated with significant declines in mental well-being and physical functioning.

2.Eleanor B. Schron, Derek V. Exner, Qing Yao,et al. Quality of Life in the Antiarrhythmics Versus Implantable Defibrillators Trial: Impact of Therapy and Influence of Adverse Symptoms and Defibrillator Shocks. Circulation. 2002;105:589-594

The limitation of this study includes:

• small number of patients;

• short time of running of trial;

• interpretation of SF-12 score.

Conclusions

• the link between clinical characteristics and QOL in patients with ICD are still incompletely defined.

• following more patients over extended periods may indicate that the clinical features correlate significantly with QOL change.

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