Quantum dots and their interaction with DNA

Maja Stanisavljević

Mendel University

Department of chemistry and biochemistry

Quantum dots – history of synthesis

1980 – Ekimov, Efros – first description

of quantum dots 1993 Murray, Norris, Bawendi CdE(E=S,SeTe) and other improvments like ZnS shellSemiconductor nanocrystals

synthetised from II and VI or III and V elements of PSE. today-enviromental-friendly

synthesis

CdTe

Characteristics

small size 1-10nm absorbtion of light in wide

range emmision range very narrow photostabillity and resistance to chemical degradation poisonous core and

hydrophobic surface modification bioconjugation

DNA

1869 – isolated by Swiss scientist

Friedrich Miescher 1953 – described DNA

structure Watson and Crick 1962 – they recieved Nobel

prize for solving nature’s biggest secret