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    1. Things considered to be specimen collection is TRUE

    A. Sputum collection doesnt need to be deep coughB. Urine specimen should be collected first-stream when you wake up early

    morning.

    C. Peritoneal fluid collection should be done under aseptic condition andkeep in universal container

    D. Serum can be collected directly from human bodyE.

    Tissue specimen keep in alcohol liquid

    2. Regarding antifungal agents are False

    A. Amphotericin B disrupt cell membraneB. Allylamines inhibit protein and DNA synthesisC. Azoles like fluconazole inhibit ergosterol synthesisD. Pyrinidine analogue inhibit protein and DNA synthesisE. Caspofungin disrupt cell wall

    3. The following fungi are transmitted by

    A. Cryptococcus can be transmitted by spore inhalationB. Sporothrix is transmitted by traumatic inplantationC. Histoplasma is droplet transmissionD. Zygomycetes is transmitted direct contactE. Main mode of candida infection is exogenous contact

    4. Normal resident of human body is True

    A. Staphylococcus Aureus is normal resident of GITB. Escherichia coli always stayed in throatC. Staphylococcus epidermidis is resident of human skin

    SECTION A : ONE BEST ANSWER (OBA):

    INSTRUCTIONS : Select ONE BEST answer from the options given below.

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    D. Mycobacterium is resident of respiratory tractE. Clostridium tetani is normal flora of skin

    5. The following are endotoxin and exotoxin producing bacteria

    A. Exotoxin can not be produced as toxoid formedB. Endotoxin is high toxicity than exotoxinC. Exotoxin produced by bacteria is low antigenicD. Endotoxin are produced by gram negative bacteriaE. Endotoxin cannot be stabled as high temperature as exotoxin

    6. Gram negative bacteria

    A.Neisseria meningitidis is rods shaped bacteriaB. Bordetella pertussis is sensitive to erythromycinC. Neisseria meningitidis growth in Thayer Martin AgarD.Neisseria gonorrhoeae is not sensitive to Penicillin

    Pseudomonas can be detected by MacConkey agar.

    7. ______ is the total elimination of ALL microorganisms including spores:

    A. SterilizationB. Disinfection

    C. Degerming

    D. Cleansing

    8. Which of the following is TRUE regarding objects intended use?

    A. Critical: objects that touch lacerated wound

    B. Semicritical : objects entering the vascular system

    C. Noncritical: objects that touch only intact skinD. High Risk: objects that touch skin abrasions

    9. The most suitable way of disposing contaminated surgical dressings and sharpsis through:

    A. Red heatB. Incineration

    C. Autoclave

    D. Irradiation

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    10. Which of the following statement is TRUE about HEAT STERILIZATION:

    A. Hot air sterilizer uses oven at 180 C 75 mins

    B. Autoclave uses 121 C, 15 psi, 15 secC. Steam sterilization includes the use of inoculating wire

    D. Autoclaving is usually used for sterilization of laboratory media

    11. The best sterilization for single use disposal items like needles & syringes,

    latex catheter, surgical gloves:

    A. Ethylene oxide

    B. IrradiationC. Glutaraldehyde

    D. Filtration

    12. Biological monitor used for Plasma Sterilization:

    A. Geobacillus stearothermophilusB. atrophaeus

    C. pumilus

    D. sporogenes

    13. The biological indicators are usually cultured in :

    A. MacConkey AgarB. soybean casein

    C. Hektoen Enteric Agar

    D. Chocolate Agar

    14. Properties of Ideal Disinfectant:A. Reactive

    B. PoisonousC. Broad spectrum

    D. Nonsoluble

    15. Which of the following statement is NOT TRUE of Factors affecting

    Disinfection:

    A. The more concentrated the disinfectant, the greater its efficacy and the shorter

    the time necessary to achieve microbial kill.

    B. In general, longer contact times are more effective than shorter contact times.C. Usual chemical reaction, twice increase in rate with each 20 C increase intemperature

    D. Microorganisms may be protected from disinfectants by production of thick

    masses of cells and extracellular materials

    16. TRUE of working dilution of Hypochlorite (bleach):

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    A. 1.5%: heavy spillage of blood/ body fluid wear

    B. 0.1% : general cleaning if need disinfection

    C. 0.25%: disinfect babies bottlesD. 1%: disinfection of hospital rooms

    17. Laboratory diagnosis of scabies is best done by:A.Fecal examination

    B.Serology

    C.Blood examination

    D.Skin scraping

    E.Rectal biopsy

    18. Skin myiasis is due to invasion of skin by:

    A.Sarcoptes scabiei

    B.Trematode cercariae

    C.Lice

    D.Fly larvae

    E.Hookworm larvae

    19. A parasitic protozoa that has pseudopodium as a mode of locomotion belon

    A.Amoebae - Sarcodina

    B.Flagellates - Mastigophora

    C.Ciliates - Ciliata

    D.SporozoaApicomplexa - Haemosporida

    E.Sporozoa - Microspora

    20. Which is not a feature of a nematode?

    A.Have straight alimentary canal

    B.Have anus

    C.Hermaphrodite

    D.Pointed both ends

    E.Dioecious

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    21. A parasitic helminth that is dorso-ventrally flattened, hermaphrodite and

    segmented belongs to:

    A.Nematoda

    B.Cestoda

    C.Trematoda

    D.Flukes

    E.Roundworms

    22. An organism that lives with another organism without harming the latter in any

    way is called a:

    A.Vector

    B.Host

    C.Symbiont

    D.Parasite

    E.Commensal

    23. An organism that can exist independently but may be parasitic on certain

    occasions is called:

    A.Endoparasite

    B.Ectoparasite

    C.Obligate parasite

    D.Commensal

    E.Facultative parasite

    24. The basic components in the host-parasite relationship are:

    A. Host, parasite and vectorB. Host, parasite and environmentC. Definitive host, intermediate host and parasiteD. Definitive host, intermediate host and vectorE. Parasite, vector and intermediate host

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    25. This host is sometimes referred to as a dead-end host.

    A. Intermediate hostB. Paratenic hostC. Reservoir hostD. Accidental hostE. Carrier host

    26. The most important difference between a biological and a mechanical vis:

    A. Whether the vector is essentiality in the life cycle of the parasiteB. The vectors role as a transmitter of the parasiteC. The species of insect that serves as a vectorD. Whether the parasite is carried on or in the vectorE. The length on time the parasite spends in the vector

    27. The main difference between infestation and infection is:

    A. Infestation is applied to parasites and infection to fungi, virusesbacteria.

    B. Infestation refers to invasion of the body by the microbes, wherinfection refers to production of symptoms due to infestation.

    C. Infestation is symbiotic, meaning organisms live in a place withharm to the host. Infections invade and destroy cells in the host.

    D. Infection leads to disease, infestation does not.E. Infestation occurs outside the body, infection is inside.

    28. In the life cycle ofBrugia malayi, one infective larva was introduced inhuman blood stream through a mosquito bite and developed into one ad

    worm in the lymphatic vessel. This type of life cycle is called:

    A. Simple life cycleB. Cyclopropagative

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    C. CyclodevelopmentalD. Domestic cycleE. Sylvatic cycle

    29. In hookworm infection, the infective larvae (or filariform larvae) penetrate

    skin and cause intense pruritic dermatitis at the site of penetration. What is

    developmental stage of these infective larvae?

    A. Infective stage

    B. Pathologic stage

    C. Diagnostic stage

    D. Infective and pathologic stageE. Infective, pathologic and diagnostic stage

    30. Which from the list below is/are the source/sources of parasitic infection?

    A. Soil

    B. Food and water

    C. Vectors

    D. Humans and animals

    E. All of the above

    31. In the infection with a protozoa, the stage that cannot produce pathology is

    A. Trpphozoite stage

    B. Schizont stage

    C. Trypomastigote stage

    D. Tissue cyst

    E. Oocyst

    32. In the infection with a helminth, the stage/stages that can cause pathology i

    the:

    A. Adult stage.

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    B. Larva stage.C. Ovum (egg) stage.D. Adult and larva stage.E. Adult, larva and ovum stage.

    33. An example of a localized manifestation of disease is:

    A. FeverB. Pruritis aniC. AnaemiaD. JaundiceE. Lethargy

    34. A sign or symptom that is so characteristic of a disease that it makes the

    diagnosis is called a:

    A. PathognomonicB. PathologicC. AnthroponoticD. SymptomaticE. Diagnostic

    35. Which of the following does not actually stain parasites?

    A. EosinB. Lugols iodineC. Trichome stainD. Acid fast stainE. Kohns stain

    36. Which of the following egg count is considered heavy forAscaris lumbrico

    infection?

    A. > 10,000 EPGB. > 20.000 EPG

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    C. >30,000 EPGD. > 40,000 EPGE. > 50,000 EPG

    37. All of these viruses have helical nucleocapsid except:

    A. RabiesB. Parainfluenza

    C. Rota virus

    D. Influenza

    38. The Tzanck test is not used on which of the following viruses?

    A. VZV

    B. HSV-2C. HHV-8

    D. HSV-1

    39. Which of the following viruses is not a single strand linear RNA virus?

    A. Togavirus

    B. Retrovirus

    C. BunyavirusD. Picornavirus

    40.Which of the following is not a DNA virus?A. Adenovirus

    B. Calicivirus

    C. Papovirus

    D. Poxvirus

    41.Which of the following is not a RNA virus?

    A. ReovirusB. Orthomyxovirus

    C. Deltavirus

    D. Herpesvirus

    42.Human immune deficiency virus is a :

    A. Rheo

    B. RetroC. Rhabdo

    D. Flavi

    43.Oncogenic RNA virus isA. Retro virus

    B. Herpes virus

    C. Adeno virusD. Hepadna virus

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    44. Portal of entry of poliovirus in mainly

    A. Gastric intestinal tract

    B. Nasal mucosaC. Lung

    D. Skin

    45. The only virus which has double double stranded RNAA. Bunya virus

    B. Reo virus

    C. Calci virusD. Rhabdo virus

    46. A 40-year-old man underwent kidney transplantation for end stage renal

    disease. Two months after transplantation, he developed fever and featuressuggestive or bilateral diffuse interstitial pneumonia. Which one of the following

    is most likely etiological agent :

    A. Herpes simplex virusB. Cytomegalovirus

    C. Epstein - Barr virus

    D. Varicella - Zoster virus

    47. What type of virus is the poxvirus ?

    A. Helical

    B. EnvelopeC. Complex

    D. Cubic

    48. True or False : Prions contain little or no nucleic acid ?A. True

    B. False

    49. All are oncogenic, but :

    A. EB Virus

    B. PapillomaC. Herpes Simplex Virus

    D. Varicella Zoster Virus

    50. A pregnant Vietnamese refugee presents for prenatal care. She mentions thatshe was sick 3 years previously, before emigrating to the US, with jaundice that

    was accompanied by intestinal upset and followed by joint pains and skin lesions

    that slowly subsided. She has felt well in the last 2 years. The possibility that this

    woman may still be harboring the infectious agent that caused her disease andthat she could transmit it to her baby is considered. Which of the following

    laboratory tests should be ordered next to investigate the causes of this womans

    past infection ?

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    A. Hepatitis B surface antigen (HBsAg)

    B. IgC Cytomegalovirus B core antigen

    C. IgM antibody to Hepatitis B core antigen (HBcAg)D. IgM antibody to HbsAg

    51.The finding of a large, multinucleated clumps of cells in the bronchialsecretions of a 2 year old girl with acute bronchopneumonia suggests that herinfection is caused by :

    A. Bordetella pertussis

    B. Epstein-Barr VirusC. Mycoplasma hominis

    D. Respiratory Syncitial Virus

    52. The following are associated with Respiratory infections except :A. Adenovirus

    B. Rotavirus

    C. Influenza virusD. RSV

    53. The following are associated with gastroenteritis except :

    A. EnterovirusB. Adenovirus

    C. Norwalk virus

    D. Rotavirus

    54. A chronic carrier state may occur in the following except :

    A. Hepatitis A

    B. Hepatitis BC. Hepatitis C

    D. Hepatitis D

    55. Oncogenes are genes which :

    A. the virus uses to replicate itself

    B. convert formaldehyde to formalin inside thecytoplasm of a cell

    C. encourage recombination in bacteria

    D. transform normal cells to cancer cells

    56. The viruses of Influenza, Measles and Mumps are known for their ability to :

    A. multiply within bacteria

    B. clump red blood cells

    C. form Negri bodies in the brainD. cause cancer

    57.Which of the following is not a DNA virus?

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    A. Adenovirus

    B. CalicivirusC. Papovirus

    D. Poxvirus

    58. Which of the following is not a RNA virus?

    A. Reovirus

    B. Orthomyxovirus

    C. DeltavirusD. Herpesvirus

    59.Which of the following viruses is not a double strand linear DNA virus?

    A. Poxvirus

    B. PapovavirusC. AdenovirusD. Herpesvirus

    60.Which of the following viruses is not a single strand linear RNA virus?

    A. TogavirusB. Retrovirus

    C. BunyavirusD. Picornavirus

    61.The Tzanck test is not used on which of the following viruses?

    A. VZV

    B. HSV-2

    C. HHV-8D. HSV-1

    62.A febrile viral illness characterized by infection and swelling of the parotidsalivary glands is produced by a large enveloped helical virus which produced

    hemadsorption of erythrocytes of infected cells. This virus is called :

    A. CytomegalovirusB. Coxsackie virue

    C. ECHO virus

    D. Mumps

    62.A helpful test in diagnosis of infectious mononucleosis is the:

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    A. Paul-Bunnell.

    B. Weil-felix.

    C. Widal.D.Blood culture.

    63.One of the following viruses produce eosinophilic intracytoplasmic inclusionbodies called Negri bodies:

    A. Herpes simplex virus.

    B. Small pox virus.D. Adenovirus.

    D. Rabies virus.

    64. Throat & nasal swabs from a 4 months old infant suffering from acute lowerrespiratory infection. Their laboratory examination revealed a large enveloped

    helical virus. The infected cell cultures revealed on staining multinucleate giant

    cells with cytoplasmic inclusions. The virus is probably:

    A. Rhinovirus.

    B. Corona virus.

    C. Adenovirus.D. Parainfluenza virus.

    65. The following viruses spread by fecal-oral route EXCEPT:

    A. Coronavirus

    B. Polioviruses.

    C. ECHo viruses.D. Hepatitis A viruses

    66. The lytic cycle involves which of the following events arranged in the properorder.

    a. Attachment Biosynthesis Penetration Maturation Release

    b. Attachment Biosynthesis Maturation PenetrationRelease

    c. Attachment Penetration Biosynthesis Maturation Release

    d. Atachment

    Penetration

    Maturation

    Biosynthesis Release

    67. Bacteriophages attach to a host cell via its

    A. capsid

    B. tail fiber

    C .plasma-membrane protein

    D. glycoprotein

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    8. Select the incorrect statement about viruses.

    A. All cellular organisms are attacked by them.B. They are parasites.

    C. They contain nucleic acids inside a protein coat.

    D. They show signs of life outside of host cells.

    69. Each of the following is used to classify viruses excepta. carbohydrate makeup c. life cycle

    b. host range. d. size

    70. A bacteriophage is (a)a. bacterium that infect bacteria c. virus that infects

    bacteria

    b.

    bacterium that infect viruses d. virus thatinfects viruses

    71. Type of cell line that usually originate from malignancy.a. Primary cell c. Heteroploid cell

    b. Diploid cell d. Complex cell

    72. The virus capsid consists of

    a. carbohydrate. c. nucleic acid

    b. lipid. d. protein

    73. Which sample material will you collect in identifying the cause of

    chickenpox?

    a. Throat swab c. tissue biopsy

    b. Lesion and vesicle swab d. blood74. In the viral life cycle, uncoating is the

    a. attachment to the host cell.

    b. entrance of the viral genome into the host cell.c. removal of the capsid and envelope.d. rupturing of the host cell.

    75. The methods to count and study bacteriophages are based on theira. analysis of RNA composition.

    b. effects on different growth media.

    c. host range and organ system preferences.

    d. mode of infecting and destroying host cells76.The burst period is when viruses

    a. do not increase in number.

    b. escape from their host.c. increase in number substantially.

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    d. rupture their capsids.

    78.The life cycle of the less virulent or temperate phage lambda isa. either the lytic or lysogenic pathway.

    b. neither the lytic nor lysogenic pathway.

    c. the lysogenic pathway only.d. the lytic pathway only.

    79.A substance is added to a bacteriophage sample. The substance destroys the

    activity of the lysozymes in the viruses. This prevents their ability toa. change their nucleic acid genetically.

    b. decrease their metabolism.

    c. dissolve the bacterial cell wall.

    d. increase their metabolism.

    80.A drop of a bacterial culture is added to an undiluted viral sample. This

    mixture is spread over a solid agar surface. After incubation, 20 circular plaquesdevelop on the lawn of bacterial cells. The number of viruses in the sample was

    probably

    a. 2 c. 200

    b. 20 d. 2000

    81.The tail fibers of an animal virus are destroyed. This will directly interfere

    with the _____________ stage of the life cycle of this virus.a. Absorption c. penetration

    b. Adsorption d. uncoating

    82.RNA-dependent RNA polymerase is needed bya. double-strand DNA viruses c. double-strand RNA viruses

    b. single-strand DNA viruses d. triple strand RNA viruses

    83.Plus-strand RNA in an HIV is used exclusively as a template for

    a. DNA replication c. transduction

    b. reverse transcription d. translation

    84.Oncogenes in cells will cause the cells to

    a. develop pigmentation c. divide too slowly

    b. divide too rapidly d. lose pigmentation

    85.The time period from penetration to assembly where the phage is unable to

    r host cell

    a. eclipse period c. burst periodb. latent period d. decline period

    1.The type of Heavy (H) chain present in the IgM immunoglobulin

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    A.Alpha

    B.Gamma

    C.EpsilonD.Mu

    E.All the above.

    2.which type of immunoglobulin transport through placental barrier.

    A.Ig A

    B.IgDC.IgG

    D.IgM

    E.IgE

    3.Substances induces mitosis of cells particular lymphocytes to undergo cell

    division

    A.immunogens.B.Mitogens

    C.mutagens.

    D.Antigens.

    E.None.

    4.the stimulating factors for B-cell activation

    A.IL 2&IL 7B.IL 3&IL 1

    C.IL 4 &IL 6

    D.IL 3&IL 4

    E.None.

    5.which phase of secondary humoral immune response there is rise in antibody

    titre.A.Log phase

    B.Lag phase

    C.Decline phaseD.Exponential phase

    E.All.

    6.The chemical substances which are produced by lymphocytes,which regulatesthe other intercells.

    A.monokines

    B.cytokines.

    C.Interleukins.D.monoclonal antibodies.

    E.None.

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    7.The substances which are injected together with antigen which enhances the

    antibody production.

    A.InterleukinsB.mitogens.

    C.Adjuvants.

    D.cytokines.E.All.

    8.The cell mediated immune response is mediated by which type of cells.

    A.sensitised T-lymphocytes.B.Plasma cells.

    C.surface markers.

    D.immunoglobulins.

    E.None.

    9.The peripheral lymphoid organ from blood stream & lymph which evokes

    immune response.A. Lymph nodes, spleen & kidneys.

    B. Lymphnodes, lymphocytes & spleen

    C.bone marrow.

    D.thymus.E.All.

    10.which type of cells are called as suppressor cells(Ts).A.CD 4

    B.CD8

    C.B-cells

    D.Plasma cells.E.memory cells.

    11.The chemical composition of gram negative cell wall.A.polysaccharides only.

    B.only peptidoglycons.

    C.peptidoglycons& lipopolysaccharidesD.teichoic acids& polypepetides.

    E.All.

    12.the mucopeptide or murein is composed of----A.N-acetyl muramic acid &N-acetyl glucosamine

    B.only N-acetly muramic acid.

    C.acetyl succinic acid.

    D.All.E.None.

    13.the staining technique which is sued for capsule demonstration.

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    A.Alberts staining.

    B.Gram staining.

    C.Negative stainingD.Z-N staining.

    E.All.

    14.Pleomorphism means.A.variation in colors of the cells.

    B.variation of shape & size of the cells

    C.variation in nutritional habits.D.variation in pathogenicity.

    E.None

    15.Fimbrae or pili composed by a protein .A.flagellin.

    B.albumin.

    C.pilinD.All

    E.None

    16.The cell organelle which is having extra chromosomal genetic material istermed as

    A.Mesosome.

    B.RibosomeC.Plasmids.

    D.Nucleus.

    E.None

    17.the mordant used in gram staining

    A.H SO

    B.carbol fuschin.C.Iodine

    D.HCl

    E.All.

    18.Z-N staining is used for differentiation of organaisms into.

    A.Gram positive & Gram negative organisms.

    B.Acid fast & non Acid fast organisms.C.Capsulated & Non capsulated organisms.

    D.motile & non motile organisms.

    E.All.

    19.Respiratory sites of bacteria are

    A.ribosomes.B.Mesosomes

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    C.pili

    D.plasmamembrane.

    E.mitochondria.

    20.Define virulence.A.The measure of degree of pathogenicity.B.The measure of toxigenecity.

    C.The measure for antigen Antibody reaction.

    D.The measure for infections.E.None.

    21.virulence factor for disease by an organism.

    A.Adherence & invasionB.multiplication&dissemination.

    C.A&B

    D.Only AE.Only B

    22.Adhesins are secreted by which structures of bacteria.

    A.flagella.B.pili or fimbrae

    C.plasma membrane.

    D.capsule.E.cytoplasm.

    23.Noscomial infections & most common organisms which causes nosocomial

    infections.A.Infections in immunocompromised patients & parasites.

    B.Infections in healthy hosts & pathogens.

    C.Infections Acquired by hospitalization & oputunistic pathogens.D.Infcetions acquired by ingestion of contaminated food & saprophytes.

    E.None.

    24.transplacental transmission of infections.

    A.infections through contaminated food.

    B.infection by contaminated water.

    C.infection through placenta from mother to childD.All.

    E.None.

    25.Heamatogenous mode of infection.A.Through blood

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    B.Through food.

    C.Through skin.

    D.Direct entry into body.E.All.

    26.A 25 year old female patient complains about urge to urinate,burningmicturination,loin pain diagnosed as UTI,on culture a gram positive organism isisolated which produces coagulase.

    A.Staph.aureus

    B.staph.epidermidisC.Staph.saprophyticus.

    D.Streptococci.

    E.enterococci.

    27. A 40 year old lady was seen urgently physician for sever suprapubic

    pain,increased urination, her urine sample sent to laboratory for urinalysis and

    urine culture.the yields a gram negative bacteria which is lactose fermenters.whatmay the organism.

    A.pseudomonas.

    B.salmonella

    C.E.coliD.Shigella

    E.All.

    28. A 2year old girl presented to physician with sore throat and fever. the tonsils

    were enlarged and inflammed.the throatswab send for culture and culture yeilds

    the growth of beta-hemolytic colonies of gram positive organism.

    A.Staphylococcus.B.Sreptococcus.pyogenes

    C.Streptococcu.pneumonia

    D.EnterococciE.None

    29.The Gram positive organism causes dental caries & endocarditis isA.Staph.aureus.

    B.Streptococci.pneumonia.

    C.Viridans streptococci

    D.Streptococcus pyogenes.E.All

    30.Mode of infection by cornybacterium diphtheria

    A.Droplet modeB.Innamiante objects.

    C.Contact mode.

    D.AllE.None.

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    31.which gram positive organism causes pseudo membranous colitis

    A.Cl.perfringes.

    B.Cl.difficleC.Enterococci.D.Cornybaccterium

    E.Bacillus

    32. A 65 year old male patient admitted to hospital with chronic granulomatous

    infection with pus draining through sinuses which open on surface of skin on

    jaws,abdomen etc.what is the causative agent of this infection.

    A.MycoplasmaB.Actinomycetes

    C.Nocardia.

    D.Rickettesia.E.Chlamydia.

    33.A 35 yr old female attended clinic withpelvic inflammatory disease,the gramstain smear results gram negative cocci in pairs ,what is causative agent.A.Nesseriae.meningitis

    B.E.coli.

    C.Shigella.D.Enterococci

    E.N.gonnorhoea

    34.A 15 yr old boy admitted in hospital with high fever,abdominalpain,diarrhea,after consumption of contaminated water,who works in poultry

    farm.what is the causative agent for this infection.

    A.shigellaB.Vibrio

    C.salmonella

    D.E.coliE.pseudomonas

    35.Atypical pneumonia is caused by

    A.UreaplasmaB.Chlamydiae.

    C.Actinomycetes.

    D.Nocardia

    E.Mycoplasma

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    Extended matching question:

    Theme: Gram negative bacterial infections.

    Options:A.Salmonella typhi.

    B.pseudomonas aeruginosa.

    C.Shigella

    D.E.coliE.Anaerobic bacteriodes.

    F.Salmonella enterocolitis

    G.Proteus spps.H.Klebsiella spps.

    Stems:

    1.A traveller from America came on vacation to developing area of malaysiasuffered with diarrohea, vomiting and abdominal pain. which subsided on

    antibiotics, what gram negative organism can we suspect.

    2.A 45 yr old male is admitted in hospital with fever, vomiting, abdominal pain,&

    diarrohea caused after ingestion of contaminated poultry food.

    3.A 12 yr girl is admitted with fever, headache, anorxea, clouding ofconsciousness due to action of toxins released by the organism

    4.A 55 year old women presented with micturination,loin pain ,pyuria suspectedcase of urinary tract infection. the urine specimen sent for urinalysis. which

    organism is responsible for UTI

    5.A 48 yrs old male patient is admitted in hospital for loose stool diarrohea with

    passage of pus, blood & mucous in stool with abdominal cramps & tenesmus, the

    microscopy yields some bacilli. what is the causative organism

    6.A 35 yr old female patient is admitted in burn ward with 50% burns.the burn

    regions are infected & lesion are with blue pus,what organism can we isolate

    from these purative lesions

    7.A 65 yr old male patient who is catheterised for several days complains for

    urge to urinate, loin pain ,incomplete voiding of urinary bladder,the culture yields

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    a gram negative non lactose fermenter.

    8.A 60 yr old male patient admitted hospital for liver abscesses,the pus fromabscesses is cultured,it yields an anerobic garm negative bacilli,which anerobe is

    responsible for infection.

    Theme : Gram positive bacterial infections

    Options:A.Staphylococcus.aureusB.Streptococcus.pyogenesC.Clostridium perfringens

    D.Clostridium botulinum

    E.Cornybacterium diptheriaeF.Viridans streptococci

    G.Bacillus anthrax

    H.Staphylococcus.epidermidis

    I.Streptococcus pneumoniae

    Stems:

    1.An opurtunistic garm positive cocci causes urinary tract infections

    2.A gram positive cocci which produces an enzyme called coagulase causes

    folliculitis,pustules etc

    3.A paediatric infection caused by gram positive bacilli

    4.A grampositive cocci which is responsible for aspirated pneumonia and

    meningitis

    5.A food poisoning case by gram positive bacilli

    6.A gram positive cocci responsible for epiglotitis,pharyngitis

    7.A infection by gram positive bacilli from animals to humans mostly from sheep

    8.infections like dental caries caused by which gram positive organisms

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    9.The skin infections like impetigo, erysipelas, cellulitis caused by which gram

    positive cocci

    10.A gram positive cocci due to release of toxin causes shock

    MODIFIED ESSAY QUESTIONS:

    1.Immune response

    A.define immune response 2 MarksB.Cell activation in immune response 4 marks

    C.discuss about cell mediated immune response 2 marks

    2.A 8 yrs girl presented with sore throat with enlarged tonsils and fever.

    A.What is the causative organism of infection 2 marks

    B.what are the virulence factors in the pathogenesis of the organism. 3

    C.Mode of infection & laboratory diagnosisD.Different species of the causative organisms

    3.A 3 yrs old boy presented with sever cough with characteristic sound whoof,

    during paroxysm.

    A.mode of infection& laboratory diagnosis

    B.what is causative organism Its morphologyC.virulence factors in detail

    D.Laboratory diagnosis

    I. Theme: Laboratory culture media of gramnegative bacteria

    Options:

    A.Neisseia MeningitidisB.Proteus

    C.Escherichia coli

    D.Neisseria gonorrhoeaE.Pseudomonas aeroginosa

    F.Vibrio Cholerae

    Lead in: For each of the statements given below, select the most appropriate

    response.

    Stems:

    1. Growth on Thayer Martin agar D2. Growth on Macconkey Agar C

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    3. Growth on chocolate agar A4. Blood agar B5. TCBS agar F

    3

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