red led and laser photobiomodulation in the prevention and treatment of oral mucositis: experimental...
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ORAL AND MAXILLOFACIAL PATHOLOGY OOOO
e188 Abstracts February 2014
techniques. Such modified techniques are a valuable choice fortreating ranula in elderly patients.
PE-290 - RECURRENT BOTRYOID ODONTOGENICCYST OF MANDIBLE. ANDRÉIA FERREIRA DO CARMO,GLEYSSON MATIAS DE ASSIS, ADRIANO ROCHAGERMANO, JOSE SANDRO PEREIRA DA SILVA, ERICKAJANINE DANTAS DA SILVEIRA, LEÃO PEREIRA PINTO,HÉBEL CAVALCANTI GALVÃO. UNIVERSIDADE FED-ERAL DO RIO GRANDE DO NORTE.
Botryoid odontogenic cyst is a rare multilocular variant oflateral periodontal cysts. Man, 55, complained of numbness andpain on palpation in the lip and chin area. Six years previouslythe patient was diagnosed with botryoid odontogenic cyst.Clinical examination revealed intact oral mucosa, no signs ofswelling, and response to cold when tooth pulps were tested.Panoramic radiography revealed a multilocular radiolucencyinvolving the anteroposterior jaw. An excisional biopsy wasdone, with the microscopic examination showing multiplecystic spaces lined by nonkeratinized cuboidal squamousepithelium consisting of a few layers, focal epithelial plaques,and clear vacuolated cells. The pathologic condition was iden-tified as botryoid odontogenic cyst. Another radiograph taken 3years later indicated recurrence and confirmed the histopatho-logical diagnosis. Size and multilocular pattern probably arethe main factors associated with recurrence. Long-term follow-up of patients diagnosed with botryoid odontogenic cyst isnecessary.
PE-291 - RED LED AND LASER PHOTOBIO-MODULATION IN THE PREVENTIONANDTREATMENTOF ORAL MUCOSITIS: EXPERIMENTAL STUDY INHAMSTERS. MARIA DO ROSÁRIO SANTOS FREIRE,RAFAEL FREITAS, FÁBIO COLOMBO, ALBERTOVALENÇA, APARECIDA MARIA CORDEIRO MARQUES,VIVIANE ALMEIDA SARMENTO. UNIVERSIDADE FED-ERAL DA BAHIA.
Animal research evaluated laser (660-nm) and LED(670-nm) irradiation and oral mucositis (OM) development afterchemotherapy (Che) with 5-fluorouracil. In the preventivegroups, photobiomodulation started 1 day before Che and wasgiven every 48 hours (Ia, IIa, Ib, IIb). For therapeutic groups(IIIa, IIIb, IVa, IVb), irradiation started the fourth day after Che.Animals were sacrificed 7 or 14 days after d(0). In the positivecontrol group, hamsters were submitted to Che without photo-biomodulation and sacrificed at 7 (Va) or 14 days (V). In thenegative control group, no procedure was done and animals weresacrificed at 7 or 14 days (Vc and Vd, respectively). Clinicalchanges and healing of OM occurred to varying degrees afterphotobiomodulation. Histologically, inflammation, predomi-nately with lymphoplasmocytes, which tended to diminish withtime; epithelial atrophy; hyperemia; fibroblast proliferation; andangiogenesis were observed. The best results were obtained inthe preventive laser and LED groups.
PE-293 - ORAL MANIFESTATIONS OF PEMPHIGUSVULGARIS: CASE REPORT. FRANCINE PESSOA DEMELO GOMES, MARUSKA CARACCIOLO DIDIER,FABIANA MOURA DA MOTTA SILVEIRA, VERÔNICAKOZMHINSKY. FACULDADE DE ODONTOLOGIA DORECIFE.
The study of dental dermatological diseases has presentedthe oral manifestations of these disorders that represent an in-tegral part or a prodromal sign of disease. In this contextpemphigus vulgaris is an important component. This study de-scribes oral lesions in patients with pemphigus vulgaris,emphasizing location, clinical features of the lesions, and thesocioeconomic profile of patients. This case study was con-ducted from August to October 2011 and followed the routineoutpatient dermatology iMIP. The women selected, ages 43 and65 years, had oral manifestations of the pemphigus vulgaris.This disease affects the oral cavity often as the initial site ofmanifestation. It is critical that dentists understand this diseaseand be able to make a diagnosis early and use that knowledge toguide treatment. Multidisciplinary care is an importantapproach.
PE-294 - ADENOID CYSTIC CARCINOMA WITHDISTINCT CLINICAL PRESENTATION: REPORT OFTWO CASES. VIVIAN DIANE PELLEGRINI, FERNANDOKENDI HORIKAWA, MARCELO MARTINSON RUIZ,KARIN SÁ FERNANDES, BIANCA BORIM PULINO,ANDREA MANTESSO POBOCIK, NORBERTO NOBUOSUGAYA. FACULDADE DE ODONTOLOGIA DAUNIVERSIDADE DE SÃO PAULO (FOUSP).
Adenoid cystic carcinoma (ACC) is a rare malignant glan-dular tumor that usually affects women and occurs in the fifth andsixth decades of life. The palate is most commonly involvedintraorally. This report presents two ACC cases with distinctclinical presentations. White woman, 20, reported swelling on theright side of the hard palate measuring 2.5 cm in diameter. It wasslightly bluish, smooth, fibrous, and painful on palpation and hadbeen present for 1 year. Asian woman, 42, presented an asymp-tomatic ulcerated fibrous nodule on the left side of the palatemeasuring 3 cm in diameter, with no color change. Both patientswere referred by dentists, and in each the diagnosis of ACC wasachieved through incisional biopsies and histopathologicalstudies. Both patients were referred to an oncology facility andunderwent surgery and adjuvant radiotherapy. The surgical defectwas restored prosthetically, and patients are being followed upperiodically.
PE-295 - RITUXIMAB AND OSTEONECROSIS OF THEJAWS: CASE STUDY. KAREN L WEIGERT, JAIROLEWGOY, DANIEL S MAZZOLENI, FABÍOLA R FRANCO,LISANDRA ENRICONI, JOSÉ HENRIQUE SASSO. PUCRS.
Treatment for B-cell non-Hodgkin’s lymphoma is com-bined therapy with cyclophosphamide, vincristine, doxoru-bicin, and prednisone. The monoclonal antibody rituximabwas later added (R-CHOP). Recently, osteonecrosis of thejaws caused by monoclonal antibodies has been observed.Man, 39, positive for human immunodeficiency virus (HIV)infection, had B-cell non-Hodgkin lymphoma. After 6 ses-sions of R-CHOP therapy, he complained of lesions in theinterdental papilla of the jaws. These were initially diagnosedas necrotizing ulcerative periodontitis but reclassified asosteonecrosis based on the observed lack of bleeding andnecrotic appearance. Ciprofloxacin and low-power laser ther-apy were initiated. After 5 weeks, the area had totallyre-epithelialized. Monoclonal antibodies are an excellentprotocol for malignant tumors, but antiangiogenic effects andneutropenia may increase the risk of jaw osteonecrosis.Patients should therefore be closely supervised by the dentist