regenerative medicine/stem cell therapy” indiana stem … annual... · derived from human embryos...

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Indiana Stem Cell Treatment Center Dr. Robert F. Jackson & Dr. Chris Lowery 9660 East 146 th Street, Suite 100 Noblesville IN 46060 317-773-6677 or 800-708-2462 www.indianastemcelltreatmentcenter.com Regenerative Medicine/Stem Cell Therapy”

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Indiana Stem Cell Treatment CenterDr Robert F Jackson amp Dr Chris Lowery

9660 East 146th Street Suite 100

Noblesville IN 46060

317-773-6677 or 800-708-2462

wwwindianastemcelltreatmentcentercom

ldquoRegenerative MedicineStem Cell

Therapyrdquo

FORMED 2010

DR MARK BERMAN COSMETIC SURGEON

DR ELLIOT LANDER UROLOGIST

FIRST MULTISPECIALTY CENTER

FIRST TO STUDY ADIPOSE DERIVED STEM CELLS UNDER IRB APPROVED RESEARCH PROTOCOLS

DEVELOPED CUSTOMIZED EQUIPMENT

DEVELOPMENT OF ldquoCELL SURGICALrdquo CONCEPT

FIRST TO FORM AN INTERNATIONAL RESEARCH NETWORK

Uses stem cells and growth factors

Repair or replace tissue or lost organ function due to

damage or congenital defects

Create living functional tissues

Stimulate previously irreparable organs to heal

themselves

A cell that can proliferate (replicate)

A cell that can differentiate (turn into other specific

cells or tissues)

EMBRYONIC

ADULT MESENCHYMAL

Can turn into any type of tissue in the whole body

Moral andor ethical issues

Derived from human embryos aborted or left over

from In Vitro Fertilization

Different DNA from host

Can form tumor cells (teratomas)

Found all over the body

Bone marrow produces continual flow of ldquomesenchymalrdquo stem cells

Fat has abundant source of mesenchymal stem cells

Multi-potent

No moral or ethical issue

Can Form BoneCartilageMuscleNerve tissue Blood vesselsConnective tissue Fat

Polypetide (protein) signaling molecules

Bone marrow (120000 cells)

Fat (aka adipose derived regenerative stem cells)

Others (cord organs)-low numbers

Mesenchyme stem cells decline with age

ALLOGENEIC- other humans

AUTOLOGOUS- (comes from your own body) so has same DNA as host and canrsquot be rejected lower risk of bacterial or viral infection

Dormant if no tissue damage or injury

They respond to tissue injury inflammation

degeneration or cell death

Tissue damage-homing properties

Cells may turn into needed tissue

Cells may provide messaging through Growth

Factors (eg cytokines) to repair damaged cells

Stem cell BIOAVAILABILITY- dormant cells

made available to damaged tissue

When additional stem cells are added to injured

areas in large numbers they can effect therapeutic

changes

Can exert local and systemic changes

New equipment and enzymes

Adipose (fat) derived stem cells are easy to harvest

Safe ndash under local anesthesia

Safe ndash Autologous (your own cells)

Abundant numbers of cells

Procedure takes 3 hours total

PART OF FAT RICH IN ADULT MESENCHYMAL STEM CELLS AND NATURAL GROWTH FACTORS

WHAT WE DEPLOY AT CALIFORNIA STEM CELL TREATMENT CENTERreg

Harvest fat under local anesthesia

Centrifuge to concentrate the fat

Add an enzyme to digest collagen tissue that binds

fat cells and stem cells

Remove stem cells (stromal vascular fraction) from bottom of syringe ndash ldquoclosed (sterile) techniquerdquo

SVF PROCUREMENT TAKES 80 MINUTES

Stemprogenitor cells

Direct injections into affected arthritic joints

Injection into difficult areas via fluoroscopy

Intravenous injection to affect systemic changes

Injection into spinal fluid or other remote areas

Directly into arteries of body or brain

Directly into soft tissues showing damage

SVF IS REGENERATIVE

SVF IS ANTI-INFLAMMATORY

SVF IS IMMUNO-MODULATORY

Orthopedics

Degenerative Diseases

Cardio-Pulmonary Diseases

Autoimmune Diseases

Urology

Neurology

Cosmetic Surgery

Spinal disk Arthritis and Chronic back or neck pain

Ankle

Hip

Knee

Tendons Ligaments Sports Injuries

Elbow Wrist

Shoulder

Prior to SVF deployment4 months after SVF deployment

End Stage CHF

Ischemic Cardiomyopathy

Acute MI

AsthmaRestrictive Lung Disease

COPDEMPHYSEMA

Not Pulmonary Fibrosis

FIBROMYALGIA

SCLERODERMA

POLYCHONDITIS

CIDP

MYASTHENIA GRAVIS

RHEUMATOID ARTHRITIS

CROHNS DISEASE

AUTO-IMMUNE HEPATITIS

RELAPSING POLYCHONDRITIS

ALOPECIA AREATA

OPTIC NEURITIS

Interstitial Cystitis

Peyronies Disease

Post prostatectomy Incontinence

Erectile Dysfunction

Int J Urol 2010 Oct17(10)896

Yamamoto T Gotoh M Hattori R Toriyama K Kamei Y Iwaguro H Matsukawa Y Funahashi Y

Periurethral injection of autologous adipose-derived stem cells for the treatment of stress urinary incontinence in patients undergoing radical prostatectomy report of two initial cases

2006

130 (45 men and 85 women with leakage)

Myoblasts (muscle stem cells) used

111 cured 17 more improved

Males 73 improved

Ultrasonography and magnetic resonance imaging showed sustained presence of the injected adipose tissue

Enhanced ultrasonography showed a progressive increase in the blood flow to the injected area

Enhanced ultrasonography showed a progressive increase in the blood flow to the injected area

Japanese protocol

Sphincteric injection of fat and SVF into muscle

Injected through scope under local anesthesia

Parkinsonrsquos

Multiple Sclerosis

Muscular Dystrophy

Neuropathy

Alzheimerrsquos and Mild Cognitive Impairment

Stroke Recovery and Brain Injury

Partial Spinal Cord Injuries

ALS

Retinitis pigmentosa

Age related- dry type- Macular Degeneration

Fortify fat grafts for better survival Face breasts buttocks hands etc

May be able to treat and improve skin quality

May be able to delay aging by adding to existing

fat

SVF alone

SVF with Neograft follicle transfer hair transplantation

Neograft alone

By far the most common type of hair restoration procedure

Involves surgery to the back of the scalp that results in a large scar

The scar will be visible with short hair Significant downtime and pain Typically good results

CRITICAL LIMB ISCHEMIA

WOUND CARE

TMJ SYNDROME

LICHEN SCLEROSIS

ANTI-AGEING

Over 300 cases with one complication

No documented cases of serious injury in human

or animals

International Stem Cell Society (ISCS) ndash reported

over 1000 registered cases Less than 2 complications of any kind

No serious adverse events

Depends on condition being treated

In 2013- we can cryopreserve cells for future use

Active Cancer

Infection

Blood Thinners

Use patients own cells

Provide service during same operative procedure

Minimally manipulate cells

Do not promote therapy or make claims

Performed as a surgical procedure (no laboratory)

Need IRB approved (FDA registered) studies to

support valid claims

International Centers (variably reputable)

Research meetings

Anecdotal and testimonial information

Early results from clinical trials

Veterinary literature

Personal experience with our own patients in USA

(more than 300)

UNIVERSITYPHARMA LABS

FDA APPROVED TRIALS

MOSTLY BONE MARROW AND

SOME EMBRYONIC

LONG TIME FOR OUTCOMES

PATENT ISSUES

FOR INSTITUTIONAL

PROFITGOVT FUNDED

DRUG MODEL

GRASSROOTS COMMUNITY

PHYSICIANrsquoS PRACTICE

BONE MARROW AND ADIPOSE

DERIVED

RAPID CLINICAL EVALUATION

WIDESPREAD AVAILABILITY

NO PATENTS NEEDED

FOR PROFITPATIENT FUNDED

NOT ldquoDRUG ORIENTEDrdquo

CSN In Association with theCalifornia Stem Cell Treatment Center

International research sharing protocols and database including Asia and Canada

High numbers of fresh autologous cells for various degenerative conditions

Standardized Multispecialty care

Advanced deployment methods

Quality Stem Cell Therapy should be available everywhere and easily accessible

WWWSTEMCELLREVOLUTIONCOM

After Three Months

Wanted to share with you the news

I was just released from my eye therapy

I am still waiting on the prism sticker for

my glasses but no more eye patch

After Four Months

I am doing GREAT I have full

vision back and havenrsquot taken my

MS shots since January

After Five Months

This is one Happy Girl

Just left my neurologist and no signs of MS for this Girl

Indiana Stem Cell Treatment CenterDr Robert F Jackson amp Dr Chris Lowery

9660 East 146th Street Suite 100

Noblesville IN 46060

317-773-6677 or 800-708-2462

wwwindianastemcelltreatmentcentercom

Thank you for your Attention

FORMED 2010

DR MARK BERMAN COSMETIC SURGEON

DR ELLIOT LANDER UROLOGIST

FIRST MULTISPECIALTY CENTER

FIRST TO STUDY ADIPOSE DERIVED STEM CELLS UNDER IRB APPROVED RESEARCH PROTOCOLS

DEVELOPED CUSTOMIZED EQUIPMENT

DEVELOPMENT OF ldquoCELL SURGICALrdquo CONCEPT

FIRST TO FORM AN INTERNATIONAL RESEARCH NETWORK

Uses stem cells and growth factors

Repair or replace tissue or lost organ function due to

damage or congenital defects

Create living functional tissues

Stimulate previously irreparable organs to heal

themselves

A cell that can proliferate (replicate)

A cell that can differentiate (turn into other specific

cells or tissues)

EMBRYONIC

ADULT MESENCHYMAL

Can turn into any type of tissue in the whole body

Moral andor ethical issues

Derived from human embryos aborted or left over

from In Vitro Fertilization

Different DNA from host

Can form tumor cells (teratomas)

Found all over the body

Bone marrow produces continual flow of ldquomesenchymalrdquo stem cells

Fat has abundant source of mesenchymal stem cells

Multi-potent

No moral or ethical issue

Can Form BoneCartilageMuscleNerve tissue Blood vesselsConnective tissue Fat

Polypetide (protein) signaling molecules

Bone marrow (120000 cells)

Fat (aka adipose derived regenerative stem cells)

Others (cord organs)-low numbers

Mesenchyme stem cells decline with age

ALLOGENEIC- other humans

AUTOLOGOUS- (comes from your own body) so has same DNA as host and canrsquot be rejected lower risk of bacterial or viral infection

Dormant if no tissue damage or injury

They respond to tissue injury inflammation

degeneration or cell death

Tissue damage-homing properties

Cells may turn into needed tissue

Cells may provide messaging through Growth

Factors (eg cytokines) to repair damaged cells

Stem cell BIOAVAILABILITY- dormant cells

made available to damaged tissue

When additional stem cells are added to injured

areas in large numbers they can effect therapeutic

changes

Can exert local and systemic changes

New equipment and enzymes

Adipose (fat) derived stem cells are easy to harvest

Safe ndash under local anesthesia

Safe ndash Autologous (your own cells)

Abundant numbers of cells

Procedure takes 3 hours total

PART OF FAT RICH IN ADULT MESENCHYMAL STEM CELLS AND NATURAL GROWTH FACTORS

WHAT WE DEPLOY AT CALIFORNIA STEM CELL TREATMENT CENTERreg

Harvest fat under local anesthesia

Centrifuge to concentrate the fat

Add an enzyme to digest collagen tissue that binds

fat cells and stem cells

Remove stem cells (stromal vascular fraction) from bottom of syringe ndash ldquoclosed (sterile) techniquerdquo

SVF PROCUREMENT TAKES 80 MINUTES

Stemprogenitor cells

Direct injections into affected arthritic joints

Injection into difficult areas via fluoroscopy

Intravenous injection to affect systemic changes

Injection into spinal fluid or other remote areas

Directly into arteries of body or brain

Directly into soft tissues showing damage

SVF IS REGENERATIVE

SVF IS ANTI-INFLAMMATORY

SVF IS IMMUNO-MODULATORY

Orthopedics

Degenerative Diseases

Cardio-Pulmonary Diseases

Autoimmune Diseases

Urology

Neurology

Cosmetic Surgery

Spinal disk Arthritis and Chronic back or neck pain

Ankle

Hip

Knee

Tendons Ligaments Sports Injuries

Elbow Wrist

Shoulder

Prior to SVF deployment4 months after SVF deployment

End Stage CHF

Ischemic Cardiomyopathy

Acute MI

AsthmaRestrictive Lung Disease

COPDEMPHYSEMA

Not Pulmonary Fibrosis

FIBROMYALGIA

SCLERODERMA

POLYCHONDITIS

CIDP

MYASTHENIA GRAVIS

RHEUMATOID ARTHRITIS

CROHNS DISEASE

AUTO-IMMUNE HEPATITIS

RELAPSING POLYCHONDRITIS

ALOPECIA AREATA

OPTIC NEURITIS

Interstitial Cystitis

Peyronies Disease

Post prostatectomy Incontinence

Erectile Dysfunction

Int J Urol 2010 Oct17(10)896

Yamamoto T Gotoh M Hattori R Toriyama K Kamei Y Iwaguro H Matsukawa Y Funahashi Y

Periurethral injection of autologous adipose-derived stem cells for the treatment of stress urinary incontinence in patients undergoing radical prostatectomy report of two initial cases

2006

130 (45 men and 85 women with leakage)

Myoblasts (muscle stem cells) used

111 cured 17 more improved

Males 73 improved

Ultrasonography and magnetic resonance imaging showed sustained presence of the injected adipose tissue

Enhanced ultrasonography showed a progressive increase in the blood flow to the injected area

Enhanced ultrasonography showed a progressive increase in the blood flow to the injected area

Japanese protocol

Sphincteric injection of fat and SVF into muscle

Injected through scope under local anesthesia

Parkinsonrsquos

Multiple Sclerosis

Muscular Dystrophy

Neuropathy

Alzheimerrsquos and Mild Cognitive Impairment

Stroke Recovery and Brain Injury

Partial Spinal Cord Injuries

ALS

Retinitis pigmentosa

Age related- dry type- Macular Degeneration

Fortify fat grafts for better survival Face breasts buttocks hands etc

May be able to treat and improve skin quality

May be able to delay aging by adding to existing

fat

SVF alone

SVF with Neograft follicle transfer hair transplantation

Neograft alone

By far the most common type of hair restoration procedure

Involves surgery to the back of the scalp that results in a large scar

The scar will be visible with short hair Significant downtime and pain Typically good results

CRITICAL LIMB ISCHEMIA

WOUND CARE

TMJ SYNDROME

LICHEN SCLEROSIS

ANTI-AGEING

Over 300 cases with one complication

No documented cases of serious injury in human

or animals

International Stem Cell Society (ISCS) ndash reported

over 1000 registered cases Less than 2 complications of any kind

No serious adverse events

Depends on condition being treated

In 2013- we can cryopreserve cells for future use

Active Cancer

Infection

Blood Thinners

Use patients own cells

Provide service during same operative procedure

Minimally manipulate cells

Do not promote therapy or make claims

Performed as a surgical procedure (no laboratory)

Need IRB approved (FDA registered) studies to

support valid claims

International Centers (variably reputable)

Research meetings

Anecdotal and testimonial information

Early results from clinical trials

Veterinary literature

Personal experience with our own patients in USA

(more than 300)

UNIVERSITYPHARMA LABS

FDA APPROVED TRIALS

MOSTLY BONE MARROW AND

SOME EMBRYONIC

LONG TIME FOR OUTCOMES

PATENT ISSUES

FOR INSTITUTIONAL

PROFITGOVT FUNDED

DRUG MODEL

GRASSROOTS COMMUNITY

PHYSICIANrsquoS PRACTICE

BONE MARROW AND ADIPOSE

DERIVED

RAPID CLINICAL EVALUATION

WIDESPREAD AVAILABILITY

NO PATENTS NEEDED

FOR PROFITPATIENT FUNDED

NOT ldquoDRUG ORIENTEDrdquo

CSN In Association with theCalifornia Stem Cell Treatment Center

International research sharing protocols and database including Asia and Canada

High numbers of fresh autologous cells for various degenerative conditions

Standardized Multispecialty care

Advanced deployment methods

Quality Stem Cell Therapy should be available everywhere and easily accessible

WWWSTEMCELLREVOLUTIONCOM

After Three Months

Wanted to share with you the news

I was just released from my eye therapy

I am still waiting on the prism sticker for

my glasses but no more eye patch

After Four Months

I am doing GREAT I have full

vision back and havenrsquot taken my

MS shots since January

After Five Months

This is one Happy Girl

Just left my neurologist and no signs of MS for this Girl

Indiana Stem Cell Treatment CenterDr Robert F Jackson amp Dr Chris Lowery

9660 East 146th Street Suite 100

Noblesville IN 46060

317-773-6677 or 800-708-2462

wwwindianastemcelltreatmentcentercom

Thank you for your Attention

Uses stem cells and growth factors

Repair or replace tissue or lost organ function due to

damage or congenital defects

Create living functional tissues

Stimulate previously irreparable organs to heal

themselves

A cell that can proliferate (replicate)

A cell that can differentiate (turn into other specific

cells or tissues)

EMBRYONIC

ADULT MESENCHYMAL

Can turn into any type of tissue in the whole body

Moral andor ethical issues

Derived from human embryos aborted or left over

from In Vitro Fertilization

Different DNA from host

Can form tumor cells (teratomas)

Found all over the body

Bone marrow produces continual flow of ldquomesenchymalrdquo stem cells

Fat has abundant source of mesenchymal stem cells

Multi-potent

No moral or ethical issue

Can Form BoneCartilageMuscleNerve tissue Blood vesselsConnective tissue Fat

Polypetide (protein) signaling molecules

Bone marrow (120000 cells)

Fat (aka adipose derived regenerative stem cells)

Others (cord organs)-low numbers

Mesenchyme stem cells decline with age

ALLOGENEIC- other humans

AUTOLOGOUS- (comes from your own body) so has same DNA as host and canrsquot be rejected lower risk of bacterial or viral infection

Dormant if no tissue damage or injury

They respond to tissue injury inflammation

degeneration or cell death

Tissue damage-homing properties

Cells may turn into needed tissue

Cells may provide messaging through Growth

Factors (eg cytokines) to repair damaged cells

Stem cell BIOAVAILABILITY- dormant cells

made available to damaged tissue

When additional stem cells are added to injured

areas in large numbers they can effect therapeutic

changes

Can exert local and systemic changes

New equipment and enzymes

Adipose (fat) derived stem cells are easy to harvest

Safe ndash under local anesthesia

Safe ndash Autologous (your own cells)

Abundant numbers of cells

Procedure takes 3 hours total

PART OF FAT RICH IN ADULT MESENCHYMAL STEM CELLS AND NATURAL GROWTH FACTORS

WHAT WE DEPLOY AT CALIFORNIA STEM CELL TREATMENT CENTERreg

Harvest fat under local anesthesia

Centrifuge to concentrate the fat

Add an enzyme to digest collagen tissue that binds

fat cells and stem cells

Remove stem cells (stromal vascular fraction) from bottom of syringe ndash ldquoclosed (sterile) techniquerdquo

SVF PROCUREMENT TAKES 80 MINUTES

Stemprogenitor cells

Direct injections into affected arthritic joints

Injection into difficult areas via fluoroscopy

Intravenous injection to affect systemic changes

Injection into spinal fluid or other remote areas

Directly into arteries of body or brain

Directly into soft tissues showing damage

SVF IS REGENERATIVE

SVF IS ANTI-INFLAMMATORY

SVF IS IMMUNO-MODULATORY

Orthopedics

Degenerative Diseases

Cardio-Pulmonary Diseases

Autoimmune Diseases

Urology

Neurology

Cosmetic Surgery

Spinal disk Arthritis and Chronic back or neck pain

Ankle

Hip

Knee

Tendons Ligaments Sports Injuries

Elbow Wrist

Shoulder

Prior to SVF deployment4 months after SVF deployment

End Stage CHF

Ischemic Cardiomyopathy

Acute MI

AsthmaRestrictive Lung Disease

COPDEMPHYSEMA

Not Pulmonary Fibrosis

FIBROMYALGIA

SCLERODERMA

POLYCHONDITIS

CIDP

MYASTHENIA GRAVIS

RHEUMATOID ARTHRITIS

CROHNS DISEASE

AUTO-IMMUNE HEPATITIS

RELAPSING POLYCHONDRITIS

ALOPECIA AREATA

OPTIC NEURITIS

Interstitial Cystitis

Peyronies Disease

Post prostatectomy Incontinence

Erectile Dysfunction

Int J Urol 2010 Oct17(10)896

Yamamoto T Gotoh M Hattori R Toriyama K Kamei Y Iwaguro H Matsukawa Y Funahashi Y

Periurethral injection of autologous adipose-derived stem cells for the treatment of stress urinary incontinence in patients undergoing radical prostatectomy report of two initial cases

2006

130 (45 men and 85 women with leakage)

Myoblasts (muscle stem cells) used

111 cured 17 more improved

Males 73 improved

Ultrasonography and magnetic resonance imaging showed sustained presence of the injected adipose tissue

Enhanced ultrasonography showed a progressive increase in the blood flow to the injected area

Enhanced ultrasonography showed a progressive increase in the blood flow to the injected area

Japanese protocol

Sphincteric injection of fat and SVF into muscle

Injected through scope under local anesthesia

Parkinsonrsquos

Multiple Sclerosis

Muscular Dystrophy

Neuropathy

Alzheimerrsquos and Mild Cognitive Impairment

Stroke Recovery and Brain Injury

Partial Spinal Cord Injuries

ALS

Retinitis pigmentosa

Age related- dry type- Macular Degeneration

Fortify fat grafts for better survival Face breasts buttocks hands etc

May be able to treat and improve skin quality

May be able to delay aging by adding to existing

fat

SVF alone

SVF with Neograft follicle transfer hair transplantation

Neograft alone

By far the most common type of hair restoration procedure

Involves surgery to the back of the scalp that results in a large scar

The scar will be visible with short hair Significant downtime and pain Typically good results

CRITICAL LIMB ISCHEMIA

WOUND CARE

TMJ SYNDROME

LICHEN SCLEROSIS

ANTI-AGEING

Over 300 cases with one complication

No documented cases of serious injury in human

or animals

International Stem Cell Society (ISCS) ndash reported

over 1000 registered cases Less than 2 complications of any kind

No serious adverse events

Depends on condition being treated

In 2013- we can cryopreserve cells for future use

Active Cancer

Infection

Blood Thinners

Use patients own cells

Provide service during same operative procedure

Minimally manipulate cells

Do not promote therapy or make claims

Performed as a surgical procedure (no laboratory)

Need IRB approved (FDA registered) studies to

support valid claims

International Centers (variably reputable)

Research meetings

Anecdotal and testimonial information

Early results from clinical trials

Veterinary literature

Personal experience with our own patients in USA

(more than 300)

UNIVERSITYPHARMA LABS

FDA APPROVED TRIALS

MOSTLY BONE MARROW AND

SOME EMBRYONIC

LONG TIME FOR OUTCOMES

PATENT ISSUES

FOR INSTITUTIONAL

PROFITGOVT FUNDED

DRUG MODEL

GRASSROOTS COMMUNITY

PHYSICIANrsquoS PRACTICE

BONE MARROW AND ADIPOSE

DERIVED

RAPID CLINICAL EVALUATION

WIDESPREAD AVAILABILITY

NO PATENTS NEEDED

FOR PROFITPATIENT FUNDED

NOT ldquoDRUG ORIENTEDrdquo

CSN In Association with theCalifornia Stem Cell Treatment Center

International research sharing protocols and database including Asia and Canada

High numbers of fresh autologous cells for various degenerative conditions

Standardized Multispecialty care

Advanced deployment methods

Quality Stem Cell Therapy should be available everywhere and easily accessible

WWWSTEMCELLREVOLUTIONCOM

After Three Months

Wanted to share with you the news

I was just released from my eye therapy

I am still waiting on the prism sticker for

my glasses but no more eye patch

After Four Months

I am doing GREAT I have full

vision back and havenrsquot taken my

MS shots since January

After Five Months

This is one Happy Girl

Just left my neurologist and no signs of MS for this Girl

Indiana Stem Cell Treatment CenterDr Robert F Jackson amp Dr Chris Lowery

9660 East 146th Street Suite 100

Noblesville IN 46060

317-773-6677 or 800-708-2462

wwwindianastemcelltreatmentcentercom

Thank you for your Attention

A cell that can proliferate (replicate)

A cell that can differentiate (turn into other specific

cells or tissues)

EMBRYONIC

ADULT MESENCHYMAL

Can turn into any type of tissue in the whole body

Moral andor ethical issues

Derived from human embryos aborted or left over

from In Vitro Fertilization

Different DNA from host

Can form tumor cells (teratomas)

Found all over the body

Bone marrow produces continual flow of ldquomesenchymalrdquo stem cells

Fat has abundant source of mesenchymal stem cells

Multi-potent

No moral or ethical issue

Can Form BoneCartilageMuscleNerve tissue Blood vesselsConnective tissue Fat

Polypetide (protein) signaling molecules

Bone marrow (120000 cells)

Fat (aka adipose derived regenerative stem cells)

Others (cord organs)-low numbers

Mesenchyme stem cells decline with age

ALLOGENEIC- other humans

AUTOLOGOUS- (comes from your own body) so has same DNA as host and canrsquot be rejected lower risk of bacterial or viral infection

Dormant if no tissue damage or injury

They respond to tissue injury inflammation

degeneration or cell death

Tissue damage-homing properties

Cells may turn into needed tissue

Cells may provide messaging through Growth

Factors (eg cytokines) to repair damaged cells

Stem cell BIOAVAILABILITY- dormant cells

made available to damaged tissue

When additional stem cells are added to injured

areas in large numbers they can effect therapeutic

changes

Can exert local and systemic changes

New equipment and enzymes

Adipose (fat) derived stem cells are easy to harvest

Safe ndash under local anesthesia

Safe ndash Autologous (your own cells)

Abundant numbers of cells

Procedure takes 3 hours total

PART OF FAT RICH IN ADULT MESENCHYMAL STEM CELLS AND NATURAL GROWTH FACTORS

WHAT WE DEPLOY AT CALIFORNIA STEM CELL TREATMENT CENTERreg

Harvest fat under local anesthesia

Centrifuge to concentrate the fat

Add an enzyme to digest collagen tissue that binds

fat cells and stem cells

Remove stem cells (stromal vascular fraction) from bottom of syringe ndash ldquoclosed (sterile) techniquerdquo

SVF PROCUREMENT TAKES 80 MINUTES

Stemprogenitor cells

Direct injections into affected arthritic joints

Injection into difficult areas via fluoroscopy

Intravenous injection to affect systemic changes

Injection into spinal fluid or other remote areas

Directly into arteries of body or brain

Directly into soft tissues showing damage

SVF IS REGENERATIVE

SVF IS ANTI-INFLAMMATORY

SVF IS IMMUNO-MODULATORY

Orthopedics

Degenerative Diseases

Cardio-Pulmonary Diseases

Autoimmune Diseases

Urology

Neurology

Cosmetic Surgery

Spinal disk Arthritis and Chronic back or neck pain

Ankle

Hip

Knee

Tendons Ligaments Sports Injuries

Elbow Wrist

Shoulder

Prior to SVF deployment4 months after SVF deployment

End Stage CHF

Ischemic Cardiomyopathy

Acute MI

AsthmaRestrictive Lung Disease

COPDEMPHYSEMA

Not Pulmonary Fibrosis

FIBROMYALGIA

SCLERODERMA

POLYCHONDITIS

CIDP

MYASTHENIA GRAVIS

RHEUMATOID ARTHRITIS

CROHNS DISEASE

AUTO-IMMUNE HEPATITIS

RELAPSING POLYCHONDRITIS

ALOPECIA AREATA

OPTIC NEURITIS

Interstitial Cystitis

Peyronies Disease

Post prostatectomy Incontinence

Erectile Dysfunction

Int J Urol 2010 Oct17(10)896

Yamamoto T Gotoh M Hattori R Toriyama K Kamei Y Iwaguro H Matsukawa Y Funahashi Y

Periurethral injection of autologous adipose-derived stem cells for the treatment of stress urinary incontinence in patients undergoing radical prostatectomy report of two initial cases

2006

130 (45 men and 85 women with leakage)

Myoblasts (muscle stem cells) used

111 cured 17 more improved

Males 73 improved

Ultrasonography and magnetic resonance imaging showed sustained presence of the injected adipose tissue

Enhanced ultrasonography showed a progressive increase in the blood flow to the injected area

Enhanced ultrasonography showed a progressive increase in the blood flow to the injected area

Japanese protocol

Sphincteric injection of fat and SVF into muscle

Injected through scope under local anesthesia

Parkinsonrsquos

Multiple Sclerosis

Muscular Dystrophy

Neuropathy

Alzheimerrsquos and Mild Cognitive Impairment

Stroke Recovery and Brain Injury

Partial Spinal Cord Injuries

ALS

Retinitis pigmentosa

Age related- dry type- Macular Degeneration

Fortify fat grafts for better survival Face breasts buttocks hands etc

May be able to treat and improve skin quality

May be able to delay aging by adding to existing

fat

SVF alone

SVF with Neograft follicle transfer hair transplantation

Neograft alone

By far the most common type of hair restoration procedure

Involves surgery to the back of the scalp that results in a large scar

The scar will be visible with short hair Significant downtime and pain Typically good results

CRITICAL LIMB ISCHEMIA

WOUND CARE

TMJ SYNDROME

LICHEN SCLEROSIS

ANTI-AGEING

Over 300 cases with one complication

No documented cases of serious injury in human

or animals

International Stem Cell Society (ISCS) ndash reported

over 1000 registered cases Less than 2 complications of any kind

No serious adverse events

Depends on condition being treated

In 2013- we can cryopreserve cells for future use

Active Cancer

Infection

Blood Thinners

Use patients own cells

Provide service during same operative procedure

Minimally manipulate cells

Do not promote therapy or make claims

Performed as a surgical procedure (no laboratory)

Need IRB approved (FDA registered) studies to

support valid claims

International Centers (variably reputable)

Research meetings

Anecdotal and testimonial information

Early results from clinical trials

Veterinary literature

Personal experience with our own patients in USA

(more than 300)

UNIVERSITYPHARMA LABS

FDA APPROVED TRIALS

MOSTLY BONE MARROW AND

SOME EMBRYONIC

LONG TIME FOR OUTCOMES

PATENT ISSUES

FOR INSTITUTIONAL

PROFITGOVT FUNDED

DRUG MODEL

GRASSROOTS COMMUNITY

PHYSICIANrsquoS PRACTICE

BONE MARROW AND ADIPOSE

DERIVED

RAPID CLINICAL EVALUATION

WIDESPREAD AVAILABILITY

NO PATENTS NEEDED

FOR PROFITPATIENT FUNDED

NOT ldquoDRUG ORIENTEDrdquo

CSN In Association with theCalifornia Stem Cell Treatment Center

International research sharing protocols and database including Asia and Canada

High numbers of fresh autologous cells for various degenerative conditions

Standardized Multispecialty care

Advanced deployment methods

Quality Stem Cell Therapy should be available everywhere and easily accessible

WWWSTEMCELLREVOLUTIONCOM

After Three Months

Wanted to share with you the news

I was just released from my eye therapy

I am still waiting on the prism sticker for

my glasses but no more eye patch

After Four Months

I am doing GREAT I have full

vision back and havenrsquot taken my

MS shots since January

After Five Months

This is one Happy Girl

Just left my neurologist and no signs of MS for this Girl

Indiana Stem Cell Treatment CenterDr Robert F Jackson amp Dr Chris Lowery

9660 East 146th Street Suite 100

Noblesville IN 46060

317-773-6677 or 800-708-2462

wwwindianastemcelltreatmentcentercom

Thank you for your Attention

EMBRYONIC

ADULT MESENCHYMAL

Can turn into any type of tissue in the whole body

Moral andor ethical issues

Derived from human embryos aborted or left over

from In Vitro Fertilization

Different DNA from host

Can form tumor cells (teratomas)

Found all over the body

Bone marrow produces continual flow of ldquomesenchymalrdquo stem cells

Fat has abundant source of mesenchymal stem cells

Multi-potent

No moral or ethical issue

Can Form BoneCartilageMuscleNerve tissue Blood vesselsConnective tissue Fat

Polypetide (protein) signaling molecules

Bone marrow (120000 cells)

Fat (aka adipose derived regenerative stem cells)

Others (cord organs)-low numbers

Mesenchyme stem cells decline with age

ALLOGENEIC- other humans

AUTOLOGOUS- (comes from your own body) so has same DNA as host and canrsquot be rejected lower risk of bacterial or viral infection

Dormant if no tissue damage or injury

They respond to tissue injury inflammation

degeneration or cell death

Tissue damage-homing properties

Cells may turn into needed tissue

Cells may provide messaging through Growth

Factors (eg cytokines) to repair damaged cells

Stem cell BIOAVAILABILITY- dormant cells

made available to damaged tissue

When additional stem cells are added to injured

areas in large numbers they can effect therapeutic

changes

Can exert local and systemic changes

New equipment and enzymes

Adipose (fat) derived stem cells are easy to harvest

Safe ndash under local anesthesia

Safe ndash Autologous (your own cells)

Abundant numbers of cells

Procedure takes 3 hours total

PART OF FAT RICH IN ADULT MESENCHYMAL STEM CELLS AND NATURAL GROWTH FACTORS

WHAT WE DEPLOY AT CALIFORNIA STEM CELL TREATMENT CENTERreg

Harvest fat under local anesthesia

Centrifuge to concentrate the fat

Add an enzyme to digest collagen tissue that binds

fat cells and stem cells

Remove stem cells (stromal vascular fraction) from bottom of syringe ndash ldquoclosed (sterile) techniquerdquo

SVF PROCUREMENT TAKES 80 MINUTES

Stemprogenitor cells

Direct injections into affected arthritic joints

Injection into difficult areas via fluoroscopy

Intravenous injection to affect systemic changes

Injection into spinal fluid or other remote areas

Directly into arteries of body or brain

Directly into soft tissues showing damage

SVF IS REGENERATIVE

SVF IS ANTI-INFLAMMATORY

SVF IS IMMUNO-MODULATORY

Orthopedics

Degenerative Diseases

Cardio-Pulmonary Diseases

Autoimmune Diseases

Urology

Neurology

Cosmetic Surgery

Spinal disk Arthritis and Chronic back or neck pain

Ankle

Hip

Knee

Tendons Ligaments Sports Injuries

Elbow Wrist

Shoulder

Prior to SVF deployment4 months after SVF deployment

End Stage CHF

Ischemic Cardiomyopathy

Acute MI

AsthmaRestrictive Lung Disease

COPDEMPHYSEMA

Not Pulmonary Fibrosis

FIBROMYALGIA

SCLERODERMA

POLYCHONDITIS

CIDP

MYASTHENIA GRAVIS

RHEUMATOID ARTHRITIS

CROHNS DISEASE

AUTO-IMMUNE HEPATITIS

RELAPSING POLYCHONDRITIS

ALOPECIA AREATA

OPTIC NEURITIS

Interstitial Cystitis

Peyronies Disease

Post prostatectomy Incontinence

Erectile Dysfunction

Int J Urol 2010 Oct17(10)896

Yamamoto T Gotoh M Hattori R Toriyama K Kamei Y Iwaguro H Matsukawa Y Funahashi Y

Periurethral injection of autologous adipose-derived stem cells for the treatment of stress urinary incontinence in patients undergoing radical prostatectomy report of two initial cases

2006

130 (45 men and 85 women with leakage)

Myoblasts (muscle stem cells) used

111 cured 17 more improved

Males 73 improved

Ultrasonography and magnetic resonance imaging showed sustained presence of the injected adipose tissue

Enhanced ultrasonography showed a progressive increase in the blood flow to the injected area

Enhanced ultrasonography showed a progressive increase in the blood flow to the injected area

Japanese protocol

Sphincteric injection of fat and SVF into muscle

Injected through scope under local anesthesia

Parkinsonrsquos

Multiple Sclerosis

Muscular Dystrophy

Neuropathy

Alzheimerrsquos and Mild Cognitive Impairment

Stroke Recovery and Brain Injury

Partial Spinal Cord Injuries

ALS

Retinitis pigmentosa

Age related- dry type- Macular Degeneration

Fortify fat grafts for better survival Face breasts buttocks hands etc

May be able to treat and improve skin quality

May be able to delay aging by adding to existing

fat

SVF alone

SVF with Neograft follicle transfer hair transplantation

Neograft alone

By far the most common type of hair restoration procedure

Involves surgery to the back of the scalp that results in a large scar

The scar will be visible with short hair Significant downtime and pain Typically good results

CRITICAL LIMB ISCHEMIA

WOUND CARE

TMJ SYNDROME

LICHEN SCLEROSIS

ANTI-AGEING

Over 300 cases with one complication

No documented cases of serious injury in human

or animals

International Stem Cell Society (ISCS) ndash reported

over 1000 registered cases Less than 2 complications of any kind

No serious adverse events

Depends on condition being treated

In 2013- we can cryopreserve cells for future use

Active Cancer

Infection

Blood Thinners

Use patients own cells

Provide service during same operative procedure

Minimally manipulate cells

Do not promote therapy or make claims

Performed as a surgical procedure (no laboratory)

Need IRB approved (FDA registered) studies to

support valid claims

International Centers (variably reputable)

Research meetings

Anecdotal and testimonial information

Early results from clinical trials

Veterinary literature

Personal experience with our own patients in USA

(more than 300)

UNIVERSITYPHARMA LABS

FDA APPROVED TRIALS

MOSTLY BONE MARROW AND

SOME EMBRYONIC

LONG TIME FOR OUTCOMES

PATENT ISSUES

FOR INSTITUTIONAL

PROFITGOVT FUNDED

DRUG MODEL

GRASSROOTS COMMUNITY

PHYSICIANrsquoS PRACTICE

BONE MARROW AND ADIPOSE

DERIVED

RAPID CLINICAL EVALUATION

WIDESPREAD AVAILABILITY

NO PATENTS NEEDED

FOR PROFITPATIENT FUNDED

NOT ldquoDRUG ORIENTEDrdquo

CSN In Association with theCalifornia Stem Cell Treatment Center

International research sharing protocols and database including Asia and Canada

High numbers of fresh autologous cells for various degenerative conditions

Standardized Multispecialty care

Advanced deployment methods

Quality Stem Cell Therapy should be available everywhere and easily accessible

WWWSTEMCELLREVOLUTIONCOM

After Three Months

Wanted to share with you the news

I was just released from my eye therapy

I am still waiting on the prism sticker for

my glasses but no more eye patch

After Four Months

I am doing GREAT I have full

vision back and havenrsquot taken my

MS shots since January

After Five Months

This is one Happy Girl

Just left my neurologist and no signs of MS for this Girl

Indiana Stem Cell Treatment CenterDr Robert F Jackson amp Dr Chris Lowery

9660 East 146th Street Suite 100

Noblesville IN 46060

317-773-6677 or 800-708-2462

wwwindianastemcelltreatmentcentercom

Thank you for your Attention

Can turn into any type of tissue in the whole body

Moral andor ethical issues

Derived from human embryos aborted or left over

from In Vitro Fertilization

Different DNA from host

Can form tumor cells (teratomas)

Found all over the body

Bone marrow produces continual flow of ldquomesenchymalrdquo stem cells

Fat has abundant source of mesenchymal stem cells

Multi-potent

No moral or ethical issue

Can Form BoneCartilageMuscleNerve tissue Blood vesselsConnective tissue Fat

Polypetide (protein) signaling molecules

Bone marrow (120000 cells)

Fat (aka adipose derived regenerative stem cells)

Others (cord organs)-low numbers

Mesenchyme stem cells decline with age

ALLOGENEIC- other humans

AUTOLOGOUS- (comes from your own body) so has same DNA as host and canrsquot be rejected lower risk of bacterial or viral infection

Dormant if no tissue damage or injury

They respond to tissue injury inflammation

degeneration or cell death

Tissue damage-homing properties

Cells may turn into needed tissue

Cells may provide messaging through Growth

Factors (eg cytokines) to repair damaged cells

Stem cell BIOAVAILABILITY- dormant cells

made available to damaged tissue

When additional stem cells are added to injured

areas in large numbers they can effect therapeutic

changes

Can exert local and systemic changes

New equipment and enzymes

Adipose (fat) derived stem cells are easy to harvest

Safe ndash under local anesthesia

Safe ndash Autologous (your own cells)

Abundant numbers of cells

Procedure takes 3 hours total

PART OF FAT RICH IN ADULT MESENCHYMAL STEM CELLS AND NATURAL GROWTH FACTORS

WHAT WE DEPLOY AT CALIFORNIA STEM CELL TREATMENT CENTERreg

Harvest fat under local anesthesia

Centrifuge to concentrate the fat

Add an enzyme to digest collagen tissue that binds

fat cells and stem cells

Remove stem cells (stromal vascular fraction) from bottom of syringe ndash ldquoclosed (sterile) techniquerdquo

SVF PROCUREMENT TAKES 80 MINUTES

Stemprogenitor cells

Direct injections into affected arthritic joints

Injection into difficult areas via fluoroscopy

Intravenous injection to affect systemic changes

Injection into spinal fluid or other remote areas

Directly into arteries of body or brain

Directly into soft tissues showing damage

SVF IS REGENERATIVE

SVF IS ANTI-INFLAMMATORY

SVF IS IMMUNO-MODULATORY

Orthopedics

Degenerative Diseases

Cardio-Pulmonary Diseases

Autoimmune Diseases

Urology

Neurology

Cosmetic Surgery

Spinal disk Arthritis and Chronic back or neck pain

Ankle

Hip

Knee

Tendons Ligaments Sports Injuries

Elbow Wrist

Shoulder

Prior to SVF deployment4 months after SVF deployment

End Stage CHF

Ischemic Cardiomyopathy

Acute MI

AsthmaRestrictive Lung Disease

COPDEMPHYSEMA

Not Pulmonary Fibrosis

FIBROMYALGIA

SCLERODERMA

POLYCHONDITIS

CIDP

MYASTHENIA GRAVIS

RHEUMATOID ARTHRITIS

CROHNS DISEASE

AUTO-IMMUNE HEPATITIS

RELAPSING POLYCHONDRITIS

ALOPECIA AREATA

OPTIC NEURITIS

Interstitial Cystitis

Peyronies Disease

Post prostatectomy Incontinence

Erectile Dysfunction

Int J Urol 2010 Oct17(10)896

Yamamoto T Gotoh M Hattori R Toriyama K Kamei Y Iwaguro H Matsukawa Y Funahashi Y

Periurethral injection of autologous adipose-derived stem cells for the treatment of stress urinary incontinence in patients undergoing radical prostatectomy report of two initial cases

2006

130 (45 men and 85 women with leakage)

Myoblasts (muscle stem cells) used

111 cured 17 more improved

Males 73 improved

Ultrasonography and magnetic resonance imaging showed sustained presence of the injected adipose tissue

Enhanced ultrasonography showed a progressive increase in the blood flow to the injected area

Enhanced ultrasonography showed a progressive increase in the blood flow to the injected area

Japanese protocol

Sphincteric injection of fat and SVF into muscle

Injected through scope under local anesthesia

Parkinsonrsquos

Multiple Sclerosis

Muscular Dystrophy

Neuropathy

Alzheimerrsquos and Mild Cognitive Impairment

Stroke Recovery and Brain Injury

Partial Spinal Cord Injuries

ALS

Retinitis pigmentosa

Age related- dry type- Macular Degeneration

Fortify fat grafts for better survival Face breasts buttocks hands etc

May be able to treat and improve skin quality

May be able to delay aging by adding to existing

fat

SVF alone

SVF with Neograft follicle transfer hair transplantation

Neograft alone

By far the most common type of hair restoration procedure

Involves surgery to the back of the scalp that results in a large scar

The scar will be visible with short hair Significant downtime and pain Typically good results

CRITICAL LIMB ISCHEMIA

WOUND CARE

TMJ SYNDROME

LICHEN SCLEROSIS

ANTI-AGEING

Over 300 cases with one complication

No documented cases of serious injury in human

or animals

International Stem Cell Society (ISCS) ndash reported

over 1000 registered cases Less than 2 complications of any kind

No serious adverse events

Depends on condition being treated

In 2013- we can cryopreserve cells for future use

Active Cancer

Infection

Blood Thinners

Use patients own cells

Provide service during same operative procedure

Minimally manipulate cells

Do not promote therapy or make claims

Performed as a surgical procedure (no laboratory)

Need IRB approved (FDA registered) studies to

support valid claims

International Centers (variably reputable)

Research meetings

Anecdotal and testimonial information

Early results from clinical trials

Veterinary literature

Personal experience with our own patients in USA

(more than 300)

UNIVERSITYPHARMA LABS

FDA APPROVED TRIALS

MOSTLY BONE MARROW AND

SOME EMBRYONIC

LONG TIME FOR OUTCOMES

PATENT ISSUES

FOR INSTITUTIONAL

PROFITGOVT FUNDED

DRUG MODEL

GRASSROOTS COMMUNITY

PHYSICIANrsquoS PRACTICE

BONE MARROW AND ADIPOSE

DERIVED

RAPID CLINICAL EVALUATION

WIDESPREAD AVAILABILITY

NO PATENTS NEEDED

FOR PROFITPATIENT FUNDED

NOT ldquoDRUG ORIENTEDrdquo

CSN In Association with theCalifornia Stem Cell Treatment Center

International research sharing protocols and database including Asia and Canada

High numbers of fresh autologous cells for various degenerative conditions

Standardized Multispecialty care

Advanced deployment methods

Quality Stem Cell Therapy should be available everywhere and easily accessible

WWWSTEMCELLREVOLUTIONCOM

After Three Months

Wanted to share with you the news

I was just released from my eye therapy

I am still waiting on the prism sticker for

my glasses but no more eye patch

After Four Months

I am doing GREAT I have full

vision back and havenrsquot taken my

MS shots since January

After Five Months

This is one Happy Girl

Just left my neurologist and no signs of MS for this Girl

Indiana Stem Cell Treatment CenterDr Robert F Jackson amp Dr Chris Lowery

9660 East 146th Street Suite 100

Noblesville IN 46060

317-773-6677 or 800-708-2462

wwwindianastemcelltreatmentcentercom

Thank you for your Attention

Found all over the body

Bone marrow produces continual flow of ldquomesenchymalrdquo stem cells

Fat has abundant source of mesenchymal stem cells

Multi-potent

No moral or ethical issue

Can Form BoneCartilageMuscleNerve tissue Blood vesselsConnective tissue Fat

Polypetide (protein) signaling molecules

Bone marrow (120000 cells)

Fat (aka adipose derived regenerative stem cells)

Others (cord organs)-low numbers

Mesenchyme stem cells decline with age

ALLOGENEIC- other humans

AUTOLOGOUS- (comes from your own body) so has same DNA as host and canrsquot be rejected lower risk of bacterial or viral infection

Dormant if no tissue damage or injury

They respond to tissue injury inflammation

degeneration or cell death

Tissue damage-homing properties

Cells may turn into needed tissue

Cells may provide messaging through Growth

Factors (eg cytokines) to repair damaged cells

Stem cell BIOAVAILABILITY- dormant cells

made available to damaged tissue

When additional stem cells are added to injured

areas in large numbers they can effect therapeutic

changes

Can exert local and systemic changes

New equipment and enzymes

Adipose (fat) derived stem cells are easy to harvest

Safe ndash under local anesthesia

Safe ndash Autologous (your own cells)

Abundant numbers of cells

Procedure takes 3 hours total

PART OF FAT RICH IN ADULT MESENCHYMAL STEM CELLS AND NATURAL GROWTH FACTORS

WHAT WE DEPLOY AT CALIFORNIA STEM CELL TREATMENT CENTERreg

Harvest fat under local anesthesia

Centrifuge to concentrate the fat

Add an enzyme to digest collagen tissue that binds

fat cells and stem cells

Remove stem cells (stromal vascular fraction) from bottom of syringe ndash ldquoclosed (sterile) techniquerdquo

SVF PROCUREMENT TAKES 80 MINUTES

Stemprogenitor cells

Direct injections into affected arthritic joints

Injection into difficult areas via fluoroscopy

Intravenous injection to affect systemic changes

Injection into spinal fluid or other remote areas

Directly into arteries of body or brain

Directly into soft tissues showing damage

SVF IS REGENERATIVE

SVF IS ANTI-INFLAMMATORY

SVF IS IMMUNO-MODULATORY

Orthopedics

Degenerative Diseases

Cardio-Pulmonary Diseases

Autoimmune Diseases

Urology

Neurology

Cosmetic Surgery

Spinal disk Arthritis and Chronic back or neck pain

Ankle

Hip

Knee

Tendons Ligaments Sports Injuries

Elbow Wrist

Shoulder

Prior to SVF deployment4 months after SVF deployment

End Stage CHF

Ischemic Cardiomyopathy

Acute MI

AsthmaRestrictive Lung Disease

COPDEMPHYSEMA

Not Pulmonary Fibrosis

FIBROMYALGIA

SCLERODERMA

POLYCHONDITIS

CIDP

MYASTHENIA GRAVIS

RHEUMATOID ARTHRITIS

CROHNS DISEASE

AUTO-IMMUNE HEPATITIS

RELAPSING POLYCHONDRITIS

ALOPECIA AREATA

OPTIC NEURITIS

Interstitial Cystitis

Peyronies Disease

Post prostatectomy Incontinence

Erectile Dysfunction

Int J Urol 2010 Oct17(10)896

Yamamoto T Gotoh M Hattori R Toriyama K Kamei Y Iwaguro H Matsukawa Y Funahashi Y

Periurethral injection of autologous adipose-derived stem cells for the treatment of stress urinary incontinence in patients undergoing radical prostatectomy report of two initial cases

2006

130 (45 men and 85 women with leakage)

Myoblasts (muscle stem cells) used

111 cured 17 more improved

Males 73 improved

Ultrasonography and magnetic resonance imaging showed sustained presence of the injected adipose tissue

Enhanced ultrasonography showed a progressive increase in the blood flow to the injected area

Enhanced ultrasonography showed a progressive increase in the blood flow to the injected area

Japanese protocol

Sphincteric injection of fat and SVF into muscle

Injected through scope under local anesthesia

Parkinsonrsquos

Multiple Sclerosis

Muscular Dystrophy

Neuropathy

Alzheimerrsquos and Mild Cognitive Impairment

Stroke Recovery and Brain Injury

Partial Spinal Cord Injuries

ALS

Retinitis pigmentosa

Age related- dry type- Macular Degeneration

Fortify fat grafts for better survival Face breasts buttocks hands etc

May be able to treat and improve skin quality

May be able to delay aging by adding to existing

fat

SVF alone

SVF with Neograft follicle transfer hair transplantation

Neograft alone

By far the most common type of hair restoration procedure

Involves surgery to the back of the scalp that results in a large scar

The scar will be visible with short hair Significant downtime and pain Typically good results

CRITICAL LIMB ISCHEMIA

WOUND CARE

TMJ SYNDROME

LICHEN SCLEROSIS

ANTI-AGEING

Over 300 cases with one complication

No documented cases of serious injury in human

or animals

International Stem Cell Society (ISCS) ndash reported

over 1000 registered cases Less than 2 complications of any kind

No serious adverse events

Depends on condition being treated

In 2013- we can cryopreserve cells for future use

Active Cancer

Infection

Blood Thinners

Use patients own cells

Provide service during same operative procedure

Minimally manipulate cells

Do not promote therapy or make claims

Performed as a surgical procedure (no laboratory)

Need IRB approved (FDA registered) studies to

support valid claims

International Centers (variably reputable)

Research meetings

Anecdotal and testimonial information

Early results from clinical trials

Veterinary literature

Personal experience with our own patients in USA

(more than 300)

UNIVERSITYPHARMA LABS

FDA APPROVED TRIALS

MOSTLY BONE MARROW AND

SOME EMBRYONIC

LONG TIME FOR OUTCOMES

PATENT ISSUES

FOR INSTITUTIONAL

PROFITGOVT FUNDED

DRUG MODEL

GRASSROOTS COMMUNITY

PHYSICIANrsquoS PRACTICE

BONE MARROW AND ADIPOSE

DERIVED

RAPID CLINICAL EVALUATION

WIDESPREAD AVAILABILITY

NO PATENTS NEEDED

FOR PROFITPATIENT FUNDED

NOT ldquoDRUG ORIENTEDrdquo

CSN In Association with theCalifornia Stem Cell Treatment Center

International research sharing protocols and database including Asia and Canada

High numbers of fresh autologous cells for various degenerative conditions

Standardized Multispecialty care

Advanced deployment methods

Quality Stem Cell Therapy should be available everywhere and easily accessible

WWWSTEMCELLREVOLUTIONCOM

After Three Months

Wanted to share with you the news

I was just released from my eye therapy

I am still waiting on the prism sticker for

my glasses but no more eye patch

After Four Months

I am doing GREAT I have full

vision back and havenrsquot taken my

MS shots since January

After Five Months

This is one Happy Girl

Just left my neurologist and no signs of MS for this Girl

Indiana Stem Cell Treatment CenterDr Robert F Jackson amp Dr Chris Lowery

9660 East 146th Street Suite 100

Noblesville IN 46060

317-773-6677 or 800-708-2462

wwwindianastemcelltreatmentcentercom

Thank you for your Attention

Can Form BoneCartilageMuscleNerve tissue Blood vesselsConnective tissue Fat

Polypetide (protein) signaling molecules

Bone marrow (120000 cells)

Fat (aka adipose derived regenerative stem cells)

Others (cord organs)-low numbers

Mesenchyme stem cells decline with age

ALLOGENEIC- other humans

AUTOLOGOUS- (comes from your own body) so has same DNA as host and canrsquot be rejected lower risk of bacterial or viral infection

Dormant if no tissue damage or injury

They respond to tissue injury inflammation

degeneration or cell death

Tissue damage-homing properties

Cells may turn into needed tissue

Cells may provide messaging through Growth

Factors (eg cytokines) to repair damaged cells

Stem cell BIOAVAILABILITY- dormant cells

made available to damaged tissue

When additional stem cells are added to injured

areas in large numbers they can effect therapeutic

changes

Can exert local and systemic changes

New equipment and enzymes

Adipose (fat) derived stem cells are easy to harvest

Safe ndash under local anesthesia

Safe ndash Autologous (your own cells)

Abundant numbers of cells

Procedure takes 3 hours total

PART OF FAT RICH IN ADULT MESENCHYMAL STEM CELLS AND NATURAL GROWTH FACTORS

WHAT WE DEPLOY AT CALIFORNIA STEM CELL TREATMENT CENTERreg

Harvest fat under local anesthesia

Centrifuge to concentrate the fat

Add an enzyme to digest collagen tissue that binds

fat cells and stem cells

Remove stem cells (stromal vascular fraction) from bottom of syringe ndash ldquoclosed (sterile) techniquerdquo

SVF PROCUREMENT TAKES 80 MINUTES

Stemprogenitor cells

Direct injections into affected arthritic joints

Injection into difficult areas via fluoroscopy

Intravenous injection to affect systemic changes

Injection into spinal fluid or other remote areas

Directly into arteries of body or brain

Directly into soft tissues showing damage

SVF IS REGENERATIVE

SVF IS ANTI-INFLAMMATORY

SVF IS IMMUNO-MODULATORY

Orthopedics

Degenerative Diseases

Cardio-Pulmonary Diseases

Autoimmune Diseases

Urology

Neurology

Cosmetic Surgery

Spinal disk Arthritis and Chronic back or neck pain

Ankle

Hip

Knee

Tendons Ligaments Sports Injuries

Elbow Wrist

Shoulder

Prior to SVF deployment4 months after SVF deployment

End Stage CHF

Ischemic Cardiomyopathy

Acute MI

AsthmaRestrictive Lung Disease

COPDEMPHYSEMA

Not Pulmonary Fibrosis

FIBROMYALGIA

SCLERODERMA

POLYCHONDITIS

CIDP

MYASTHENIA GRAVIS

RHEUMATOID ARTHRITIS

CROHNS DISEASE

AUTO-IMMUNE HEPATITIS

RELAPSING POLYCHONDRITIS

ALOPECIA AREATA

OPTIC NEURITIS

Interstitial Cystitis

Peyronies Disease

Post prostatectomy Incontinence

Erectile Dysfunction

Int J Urol 2010 Oct17(10)896

Yamamoto T Gotoh M Hattori R Toriyama K Kamei Y Iwaguro H Matsukawa Y Funahashi Y

Periurethral injection of autologous adipose-derived stem cells for the treatment of stress urinary incontinence in patients undergoing radical prostatectomy report of two initial cases

2006

130 (45 men and 85 women with leakage)

Myoblasts (muscle stem cells) used

111 cured 17 more improved

Males 73 improved

Ultrasonography and magnetic resonance imaging showed sustained presence of the injected adipose tissue

Enhanced ultrasonography showed a progressive increase in the blood flow to the injected area

Enhanced ultrasonography showed a progressive increase in the blood flow to the injected area

Japanese protocol

Sphincteric injection of fat and SVF into muscle

Injected through scope under local anesthesia

Parkinsonrsquos

Multiple Sclerosis

Muscular Dystrophy

Neuropathy

Alzheimerrsquos and Mild Cognitive Impairment

Stroke Recovery and Brain Injury

Partial Spinal Cord Injuries

ALS

Retinitis pigmentosa

Age related- dry type- Macular Degeneration

Fortify fat grafts for better survival Face breasts buttocks hands etc

May be able to treat and improve skin quality

May be able to delay aging by adding to existing

fat

SVF alone

SVF with Neograft follicle transfer hair transplantation

Neograft alone

By far the most common type of hair restoration procedure

Involves surgery to the back of the scalp that results in a large scar

The scar will be visible with short hair Significant downtime and pain Typically good results

CRITICAL LIMB ISCHEMIA

WOUND CARE

TMJ SYNDROME

LICHEN SCLEROSIS

ANTI-AGEING

Over 300 cases with one complication

No documented cases of serious injury in human

or animals

International Stem Cell Society (ISCS) ndash reported

over 1000 registered cases Less than 2 complications of any kind

No serious adverse events

Depends on condition being treated

In 2013- we can cryopreserve cells for future use

Active Cancer

Infection

Blood Thinners

Use patients own cells

Provide service during same operative procedure

Minimally manipulate cells

Do not promote therapy or make claims

Performed as a surgical procedure (no laboratory)

Need IRB approved (FDA registered) studies to

support valid claims

International Centers (variably reputable)

Research meetings

Anecdotal and testimonial information

Early results from clinical trials

Veterinary literature

Personal experience with our own patients in USA

(more than 300)

UNIVERSITYPHARMA LABS

FDA APPROVED TRIALS

MOSTLY BONE MARROW AND

SOME EMBRYONIC

LONG TIME FOR OUTCOMES

PATENT ISSUES

FOR INSTITUTIONAL

PROFITGOVT FUNDED

DRUG MODEL

GRASSROOTS COMMUNITY

PHYSICIANrsquoS PRACTICE

BONE MARROW AND ADIPOSE

DERIVED

RAPID CLINICAL EVALUATION

WIDESPREAD AVAILABILITY

NO PATENTS NEEDED

FOR PROFITPATIENT FUNDED

NOT ldquoDRUG ORIENTEDrdquo

CSN In Association with theCalifornia Stem Cell Treatment Center

International research sharing protocols and database including Asia and Canada

High numbers of fresh autologous cells for various degenerative conditions

Standardized Multispecialty care

Advanced deployment methods

Quality Stem Cell Therapy should be available everywhere and easily accessible

WWWSTEMCELLREVOLUTIONCOM

After Three Months

Wanted to share with you the news

I was just released from my eye therapy

I am still waiting on the prism sticker for

my glasses but no more eye patch

After Four Months

I am doing GREAT I have full

vision back and havenrsquot taken my

MS shots since January

After Five Months

This is one Happy Girl

Just left my neurologist and no signs of MS for this Girl

Indiana Stem Cell Treatment CenterDr Robert F Jackson amp Dr Chris Lowery

9660 East 146th Street Suite 100

Noblesville IN 46060

317-773-6677 or 800-708-2462

wwwindianastemcelltreatmentcentercom

Thank you for your Attention

Polypetide (protein) signaling molecules

Bone marrow (120000 cells)

Fat (aka adipose derived regenerative stem cells)

Others (cord organs)-low numbers

Mesenchyme stem cells decline with age

ALLOGENEIC- other humans

AUTOLOGOUS- (comes from your own body) so has same DNA as host and canrsquot be rejected lower risk of bacterial or viral infection

Dormant if no tissue damage or injury

They respond to tissue injury inflammation

degeneration or cell death

Tissue damage-homing properties

Cells may turn into needed tissue

Cells may provide messaging through Growth

Factors (eg cytokines) to repair damaged cells

Stem cell BIOAVAILABILITY- dormant cells

made available to damaged tissue

When additional stem cells are added to injured

areas in large numbers they can effect therapeutic

changes

Can exert local and systemic changes

New equipment and enzymes

Adipose (fat) derived stem cells are easy to harvest

Safe ndash under local anesthesia

Safe ndash Autologous (your own cells)

Abundant numbers of cells

Procedure takes 3 hours total

PART OF FAT RICH IN ADULT MESENCHYMAL STEM CELLS AND NATURAL GROWTH FACTORS

WHAT WE DEPLOY AT CALIFORNIA STEM CELL TREATMENT CENTERreg

Harvest fat under local anesthesia

Centrifuge to concentrate the fat

Add an enzyme to digest collagen tissue that binds

fat cells and stem cells

Remove stem cells (stromal vascular fraction) from bottom of syringe ndash ldquoclosed (sterile) techniquerdquo

SVF PROCUREMENT TAKES 80 MINUTES

Stemprogenitor cells

Direct injections into affected arthritic joints

Injection into difficult areas via fluoroscopy

Intravenous injection to affect systemic changes

Injection into spinal fluid or other remote areas

Directly into arteries of body or brain

Directly into soft tissues showing damage

SVF IS REGENERATIVE

SVF IS ANTI-INFLAMMATORY

SVF IS IMMUNO-MODULATORY

Orthopedics

Degenerative Diseases

Cardio-Pulmonary Diseases

Autoimmune Diseases

Urology

Neurology

Cosmetic Surgery

Spinal disk Arthritis and Chronic back or neck pain

Ankle

Hip

Knee

Tendons Ligaments Sports Injuries

Elbow Wrist

Shoulder

Prior to SVF deployment4 months after SVF deployment

End Stage CHF

Ischemic Cardiomyopathy

Acute MI

AsthmaRestrictive Lung Disease

COPDEMPHYSEMA

Not Pulmonary Fibrosis

FIBROMYALGIA

SCLERODERMA

POLYCHONDITIS

CIDP

MYASTHENIA GRAVIS

RHEUMATOID ARTHRITIS

CROHNS DISEASE

AUTO-IMMUNE HEPATITIS

RELAPSING POLYCHONDRITIS

ALOPECIA AREATA

OPTIC NEURITIS

Interstitial Cystitis

Peyronies Disease

Post prostatectomy Incontinence

Erectile Dysfunction

Int J Urol 2010 Oct17(10)896

Yamamoto T Gotoh M Hattori R Toriyama K Kamei Y Iwaguro H Matsukawa Y Funahashi Y

Periurethral injection of autologous adipose-derived stem cells for the treatment of stress urinary incontinence in patients undergoing radical prostatectomy report of two initial cases

2006

130 (45 men and 85 women with leakage)

Myoblasts (muscle stem cells) used

111 cured 17 more improved

Males 73 improved

Ultrasonography and magnetic resonance imaging showed sustained presence of the injected adipose tissue

Enhanced ultrasonography showed a progressive increase in the blood flow to the injected area

Enhanced ultrasonography showed a progressive increase in the blood flow to the injected area

Japanese protocol

Sphincteric injection of fat and SVF into muscle

Injected through scope under local anesthesia

Parkinsonrsquos

Multiple Sclerosis

Muscular Dystrophy

Neuropathy

Alzheimerrsquos and Mild Cognitive Impairment

Stroke Recovery and Brain Injury

Partial Spinal Cord Injuries

ALS

Retinitis pigmentosa

Age related- dry type- Macular Degeneration

Fortify fat grafts for better survival Face breasts buttocks hands etc

May be able to treat and improve skin quality

May be able to delay aging by adding to existing

fat

SVF alone

SVF with Neograft follicle transfer hair transplantation

Neograft alone

By far the most common type of hair restoration procedure

Involves surgery to the back of the scalp that results in a large scar

The scar will be visible with short hair Significant downtime and pain Typically good results

CRITICAL LIMB ISCHEMIA

WOUND CARE

TMJ SYNDROME

LICHEN SCLEROSIS

ANTI-AGEING

Over 300 cases with one complication

No documented cases of serious injury in human

or animals

International Stem Cell Society (ISCS) ndash reported

over 1000 registered cases Less than 2 complications of any kind

No serious adverse events

Depends on condition being treated

In 2013- we can cryopreserve cells for future use

Active Cancer

Infection

Blood Thinners

Use patients own cells

Provide service during same operative procedure

Minimally manipulate cells

Do not promote therapy or make claims

Performed as a surgical procedure (no laboratory)

Need IRB approved (FDA registered) studies to

support valid claims

International Centers (variably reputable)

Research meetings

Anecdotal and testimonial information

Early results from clinical trials

Veterinary literature

Personal experience with our own patients in USA

(more than 300)

UNIVERSITYPHARMA LABS

FDA APPROVED TRIALS

MOSTLY BONE MARROW AND

SOME EMBRYONIC

LONG TIME FOR OUTCOMES

PATENT ISSUES

FOR INSTITUTIONAL

PROFITGOVT FUNDED

DRUG MODEL

GRASSROOTS COMMUNITY

PHYSICIANrsquoS PRACTICE

BONE MARROW AND ADIPOSE

DERIVED

RAPID CLINICAL EVALUATION

WIDESPREAD AVAILABILITY

NO PATENTS NEEDED

FOR PROFITPATIENT FUNDED

NOT ldquoDRUG ORIENTEDrdquo

CSN In Association with theCalifornia Stem Cell Treatment Center

International research sharing protocols and database including Asia and Canada

High numbers of fresh autologous cells for various degenerative conditions

Standardized Multispecialty care

Advanced deployment methods

Quality Stem Cell Therapy should be available everywhere and easily accessible

WWWSTEMCELLREVOLUTIONCOM

After Three Months

Wanted to share with you the news

I was just released from my eye therapy

I am still waiting on the prism sticker for

my glasses but no more eye patch

After Four Months

I am doing GREAT I have full

vision back and havenrsquot taken my

MS shots since January

After Five Months

This is one Happy Girl

Just left my neurologist and no signs of MS for this Girl

Indiana Stem Cell Treatment CenterDr Robert F Jackson amp Dr Chris Lowery

9660 East 146th Street Suite 100

Noblesville IN 46060

317-773-6677 or 800-708-2462

wwwindianastemcelltreatmentcentercom

Thank you for your Attention

Bone marrow (120000 cells)

Fat (aka adipose derived regenerative stem cells)

Others (cord organs)-low numbers

Mesenchyme stem cells decline with age

ALLOGENEIC- other humans

AUTOLOGOUS- (comes from your own body) so has same DNA as host and canrsquot be rejected lower risk of bacterial or viral infection

Dormant if no tissue damage or injury

They respond to tissue injury inflammation

degeneration or cell death

Tissue damage-homing properties

Cells may turn into needed tissue

Cells may provide messaging through Growth

Factors (eg cytokines) to repair damaged cells

Stem cell BIOAVAILABILITY- dormant cells

made available to damaged tissue

When additional stem cells are added to injured

areas in large numbers they can effect therapeutic

changes

Can exert local and systemic changes

New equipment and enzymes

Adipose (fat) derived stem cells are easy to harvest

Safe ndash under local anesthesia

Safe ndash Autologous (your own cells)

Abundant numbers of cells

Procedure takes 3 hours total

PART OF FAT RICH IN ADULT MESENCHYMAL STEM CELLS AND NATURAL GROWTH FACTORS

WHAT WE DEPLOY AT CALIFORNIA STEM CELL TREATMENT CENTERreg

Harvest fat under local anesthesia

Centrifuge to concentrate the fat

Add an enzyme to digest collagen tissue that binds

fat cells and stem cells

Remove stem cells (stromal vascular fraction) from bottom of syringe ndash ldquoclosed (sterile) techniquerdquo

SVF PROCUREMENT TAKES 80 MINUTES

Stemprogenitor cells

Direct injections into affected arthritic joints

Injection into difficult areas via fluoroscopy

Intravenous injection to affect systemic changes

Injection into spinal fluid or other remote areas

Directly into arteries of body or brain

Directly into soft tissues showing damage

SVF IS REGENERATIVE

SVF IS ANTI-INFLAMMATORY

SVF IS IMMUNO-MODULATORY

Orthopedics

Degenerative Diseases

Cardio-Pulmonary Diseases

Autoimmune Diseases

Urology

Neurology

Cosmetic Surgery

Spinal disk Arthritis and Chronic back or neck pain

Ankle

Hip

Knee

Tendons Ligaments Sports Injuries

Elbow Wrist

Shoulder

Prior to SVF deployment4 months after SVF deployment

End Stage CHF

Ischemic Cardiomyopathy

Acute MI

AsthmaRestrictive Lung Disease

COPDEMPHYSEMA

Not Pulmonary Fibrosis

FIBROMYALGIA

SCLERODERMA

POLYCHONDITIS

CIDP

MYASTHENIA GRAVIS

RHEUMATOID ARTHRITIS

CROHNS DISEASE

AUTO-IMMUNE HEPATITIS

RELAPSING POLYCHONDRITIS

ALOPECIA AREATA

OPTIC NEURITIS

Interstitial Cystitis

Peyronies Disease

Post prostatectomy Incontinence

Erectile Dysfunction

Int J Urol 2010 Oct17(10)896

Yamamoto T Gotoh M Hattori R Toriyama K Kamei Y Iwaguro H Matsukawa Y Funahashi Y

Periurethral injection of autologous adipose-derived stem cells for the treatment of stress urinary incontinence in patients undergoing radical prostatectomy report of two initial cases

2006

130 (45 men and 85 women with leakage)

Myoblasts (muscle stem cells) used

111 cured 17 more improved

Males 73 improved

Ultrasonography and magnetic resonance imaging showed sustained presence of the injected adipose tissue

Enhanced ultrasonography showed a progressive increase in the blood flow to the injected area

Enhanced ultrasonography showed a progressive increase in the blood flow to the injected area

Japanese protocol

Sphincteric injection of fat and SVF into muscle

Injected through scope under local anesthesia

Parkinsonrsquos

Multiple Sclerosis

Muscular Dystrophy

Neuropathy

Alzheimerrsquos and Mild Cognitive Impairment

Stroke Recovery and Brain Injury

Partial Spinal Cord Injuries

ALS

Retinitis pigmentosa

Age related- dry type- Macular Degeneration

Fortify fat grafts for better survival Face breasts buttocks hands etc

May be able to treat and improve skin quality

May be able to delay aging by adding to existing

fat

SVF alone

SVF with Neograft follicle transfer hair transplantation

Neograft alone

By far the most common type of hair restoration procedure

Involves surgery to the back of the scalp that results in a large scar

The scar will be visible with short hair Significant downtime and pain Typically good results

CRITICAL LIMB ISCHEMIA

WOUND CARE

TMJ SYNDROME

LICHEN SCLEROSIS

ANTI-AGEING

Over 300 cases with one complication

No documented cases of serious injury in human

or animals

International Stem Cell Society (ISCS) ndash reported

over 1000 registered cases Less than 2 complications of any kind

No serious adverse events

Depends on condition being treated

In 2013- we can cryopreserve cells for future use

Active Cancer

Infection

Blood Thinners

Use patients own cells

Provide service during same operative procedure

Minimally manipulate cells

Do not promote therapy or make claims

Performed as a surgical procedure (no laboratory)

Need IRB approved (FDA registered) studies to

support valid claims

International Centers (variably reputable)

Research meetings

Anecdotal and testimonial information

Early results from clinical trials

Veterinary literature

Personal experience with our own patients in USA

(more than 300)

UNIVERSITYPHARMA LABS

FDA APPROVED TRIALS

MOSTLY BONE MARROW AND

SOME EMBRYONIC

LONG TIME FOR OUTCOMES

PATENT ISSUES

FOR INSTITUTIONAL

PROFITGOVT FUNDED

DRUG MODEL

GRASSROOTS COMMUNITY

PHYSICIANrsquoS PRACTICE

BONE MARROW AND ADIPOSE

DERIVED

RAPID CLINICAL EVALUATION

WIDESPREAD AVAILABILITY

NO PATENTS NEEDED

FOR PROFITPATIENT FUNDED

NOT ldquoDRUG ORIENTEDrdquo

CSN In Association with theCalifornia Stem Cell Treatment Center

International research sharing protocols and database including Asia and Canada

High numbers of fresh autologous cells for various degenerative conditions

Standardized Multispecialty care

Advanced deployment methods

Quality Stem Cell Therapy should be available everywhere and easily accessible

WWWSTEMCELLREVOLUTIONCOM

After Three Months

Wanted to share with you the news

I was just released from my eye therapy

I am still waiting on the prism sticker for

my glasses but no more eye patch

After Four Months

I am doing GREAT I have full

vision back and havenrsquot taken my

MS shots since January

After Five Months

This is one Happy Girl

Just left my neurologist and no signs of MS for this Girl

Indiana Stem Cell Treatment CenterDr Robert F Jackson amp Dr Chris Lowery

9660 East 146th Street Suite 100

Noblesville IN 46060

317-773-6677 or 800-708-2462

wwwindianastemcelltreatmentcentercom

Thank you for your Attention

Mesenchyme stem cells decline with age

ALLOGENEIC- other humans

AUTOLOGOUS- (comes from your own body) so has same DNA as host and canrsquot be rejected lower risk of bacterial or viral infection

Dormant if no tissue damage or injury

They respond to tissue injury inflammation

degeneration or cell death

Tissue damage-homing properties

Cells may turn into needed tissue

Cells may provide messaging through Growth

Factors (eg cytokines) to repair damaged cells

Stem cell BIOAVAILABILITY- dormant cells

made available to damaged tissue

When additional stem cells are added to injured

areas in large numbers they can effect therapeutic

changes

Can exert local and systemic changes

New equipment and enzymes

Adipose (fat) derived stem cells are easy to harvest

Safe ndash under local anesthesia

Safe ndash Autologous (your own cells)

Abundant numbers of cells

Procedure takes 3 hours total

PART OF FAT RICH IN ADULT MESENCHYMAL STEM CELLS AND NATURAL GROWTH FACTORS

WHAT WE DEPLOY AT CALIFORNIA STEM CELL TREATMENT CENTERreg

Harvest fat under local anesthesia

Centrifuge to concentrate the fat

Add an enzyme to digest collagen tissue that binds

fat cells and stem cells

Remove stem cells (stromal vascular fraction) from bottom of syringe ndash ldquoclosed (sterile) techniquerdquo

SVF PROCUREMENT TAKES 80 MINUTES

Stemprogenitor cells

Direct injections into affected arthritic joints

Injection into difficult areas via fluoroscopy

Intravenous injection to affect systemic changes

Injection into spinal fluid or other remote areas

Directly into arteries of body or brain

Directly into soft tissues showing damage

SVF IS REGENERATIVE

SVF IS ANTI-INFLAMMATORY

SVF IS IMMUNO-MODULATORY

Orthopedics

Degenerative Diseases

Cardio-Pulmonary Diseases

Autoimmune Diseases

Urology

Neurology

Cosmetic Surgery

Spinal disk Arthritis and Chronic back or neck pain

Ankle

Hip

Knee

Tendons Ligaments Sports Injuries

Elbow Wrist

Shoulder

Prior to SVF deployment4 months after SVF deployment

End Stage CHF

Ischemic Cardiomyopathy

Acute MI

AsthmaRestrictive Lung Disease

COPDEMPHYSEMA

Not Pulmonary Fibrosis

FIBROMYALGIA

SCLERODERMA

POLYCHONDITIS

CIDP

MYASTHENIA GRAVIS

RHEUMATOID ARTHRITIS

CROHNS DISEASE

AUTO-IMMUNE HEPATITIS

RELAPSING POLYCHONDRITIS

ALOPECIA AREATA

OPTIC NEURITIS

Interstitial Cystitis

Peyronies Disease

Post prostatectomy Incontinence

Erectile Dysfunction

Int J Urol 2010 Oct17(10)896

Yamamoto T Gotoh M Hattori R Toriyama K Kamei Y Iwaguro H Matsukawa Y Funahashi Y

Periurethral injection of autologous adipose-derived stem cells for the treatment of stress urinary incontinence in patients undergoing radical prostatectomy report of two initial cases

2006

130 (45 men and 85 women with leakage)

Myoblasts (muscle stem cells) used

111 cured 17 more improved

Males 73 improved

Ultrasonography and magnetic resonance imaging showed sustained presence of the injected adipose tissue

Enhanced ultrasonography showed a progressive increase in the blood flow to the injected area

Enhanced ultrasonography showed a progressive increase in the blood flow to the injected area

Japanese protocol

Sphincteric injection of fat and SVF into muscle

Injected through scope under local anesthesia

Parkinsonrsquos

Multiple Sclerosis

Muscular Dystrophy

Neuropathy

Alzheimerrsquos and Mild Cognitive Impairment

Stroke Recovery and Brain Injury

Partial Spinal Cord Injuries

ALS

Retinitis pigmentosa

Age related- dry type- Macular Degeneration

Fortify fat grafts for better survival Face breasts buttocks hands etc

May be able to treat and improve skin quality

May be able to delay aging by adding to existing

fat

SVF alone

SVF with Neograft follicle transfer hair transplantation

Neograft alone

By far the most common type of hair restoration procedure

Involves surgery to the back of the scalp that results in a large scar

The scar will be visible with short hair Significant downtime and pain Typically good results

CRITICAL LIMB ISCHEMIA

WOUND CARE

TMJ SYNDROME

LICHEN SCLEROSIS

ANTI-AGEING

Over 300 cases with one complication

No documented cases of serious injury in human

or animals

International Stem Cell Society (ISCS) ndash reported

over 1000 registered cases Less than 2 complications of any kind

No serious adverse events

Depends on condition being treated

In 2013- we can cryopreserve cells for future use

Active Cancer

Infection

Blood Thinners

Use patients own cells

Provide service during same operative procedure

Minimally manipulate cells

Do not promote therapy or make claims

Performed as a surgical procedure (no laboratory)

Need IRB approved (FDA registered) studies to

support valid claims

International Centers (variably reputable)

Research meetings

Anecdotal and testimonial information

Early results from clinical trials

Veterinary literature

Personal experience with our own patients in USA

(more than 300)

UNIVERSITYPHARMA LABS

FDA APPROVED TRIALS

MOSTLY BONE MARROW AND

SOME EMBRYONIC

LONG TIME FOR OUTCOMES

PATENT ISSUES

FOR INSTITUTIONAL

PROFITGOVT FUNDED

DRUG MODEL

GRASSROOTS COMMUNITY

PHYSICIANrsquoS PRACTICE

BONE MARROW AND ADIPOSE

DERIVED

RAPID CLINICAL EVALUATION

WIDESPREAD AVAILABILITY

NO PATENTS NEEDED

FOR PROFITPATIENT FUNDED

NOT ldquoDRUG ORIENTEDrdquo

CSN In Association with theCalifornia Stem Cell Treatment Center

International research sharing protocols and database including Asia and Canada

High numbers of fresh autologous cells for various degenerative conditions

Standardized Multispecialty care

Advanced deployment methods

Quality Stem Cell Therapy should be available everywhere and easily accessible

WWWSTEMCELLREVOLUTIONCOM

After Three Months

Wanted to share with you the news

I was just released from my eye therapy

I am still waiting on the prism sticker for

my glasses but no more eye patch

After Four Months

I am doing GREAT I have full

vision back and havenrsquot taken my

MS shots since January

After Five Months

This is one Happy Girl

Just left my neurologist and no signs of MS for this Girl

Indiana Stem Cell Treatment CenterDr Robert F Jackson amp Dr Chris Lowery

9660 East 146th Street Suite 100

Noblesville IN 46060

317-773-6677 or 800-708-2462

wwwindianastemcelltreatmentcentercom

Thank you for your Attention

ALLOGENEIC- other humans

AUTOLOGOUS- (comes from your own body) so has same DNA as host and canrsquot be rejected lower risk of bacterial or viral infection

Dormant if no tissue damage or injury

They respond to tissue injury inflammation

degeneration or cell death

Tissue damage-homing properties

Cells may turn into needed tissue

Cells may provide messaging through Growth

Factors (eg cytokines) to repair damaged cells

Stem cell BIOAVAILABILITY- dormant cells

made available to damaged tissue

When additional stem cells are added to injured

areas in large numbers they can effect therapeutic

changes

Can exert local and systemic changes

New equipment and enzymes

Adipose (fat) derived stem cells are easy to harvest

Safe ndash under local anesthesia

Safe ndash Autologous (your own cells)

Abundant numbers of cells

Procedure takes 3 hours total

PART OF FAT RICH IN ADULT MESENCHYMAL STEM CELLS AND NATURAL GROWTH FACTORS

WHAT WE DEPLOY AT CALIFORNIA STEM CELL TREATMENT CENTERreg

Harvest fat under local anesthesia

Centrifuge to concentrate the fat

Add an enzyme to digest collagen tissue that binds

fat cells and stem cells

Remove stem cells (stromal vascular fraction) from bottom of syringe ndash ldquoclosed (sterile) techniquerdquo

SVF PROCUREMENT TAKES 80 MINUTES

Stemprogenitor cells

Direct injections into affected arthritic joints

Injection into difficult areas via fluoroscopy

Intravenous injection to affect systemic changes

Injection into spinal fluid or other remote areas

Directly into arteries of body or brain

Directly into soft tissues showing damage

SVF IS REGENERATIVE

SVF IS ANTI-INFLAMMATORY

SVF IS IMMUNO-MODULATORY

Orthopedics

Degenerative Diseases

Cardio-Pulmonary Diseases

Autoimmune Diseases

Urology

Neurology

Cosmetic Surgery

Spinal disk Arthritis and Chronic back or neck pain

Ankle

Hip

Knee

Tendons Ligaments Sports Injuries

Elbow Wrist

Shoulder

Prior to SVF deployment4 months after SVF deployment

End Stage CHF

Ischemic Cardiomyopathy

Acute MI

AsthmaRestrictive Lung Disease

COPDEMPHYSEMA

Not Pulmonary Fibrosis

FIBROMYALGIA

SCLERODERMA

POLYCHONDITIS

CIDP

MYASTHENIA GRAVIS

RHEUMATOID ARTHRITIS

CROHNS DISEASE

AUTO-IMMUNE HEPATITIS

RELAPSING POLYCHONDRITIS

ALOPECIA AREATA

OPTIC NEURITIS

Interstitial Cystitis

Peyronies Disease

Post prostatectomy Incontinence

Erectile Dysfunction

Int J Urol 2010 Oct17(10)896

Yamamoto T Gotoh M Hattori R Toriyama K Kamei Y Iwaguro H Matsukawa Y Funahashi Y

Periurethral injection of autologous adipose-derived stem cells for the treatment of stress urinary incontinence in patients undergoing radical prostatectomy report of two initial cases

2006

130 (45 men and 85 women with leakage)

Myoblasts (muscle stem cells) used

111 cured 17 more improved

Males 73 improved

Ultrasonography and magnetic resonance imaging showed sustained presence of the injected adipose tissue

Enhanced ultrasonography showed a progressive increase in the blood flow to the injected area

Enhanced ultrasonography showed a progressive increase in the blood flow to the injected area

Japanese protocol

Sphincteric injection of fat and SVF into muscle

Injected through scope under local anesthesia

Parkinsonrsquos

Multiple Sclerosis

Muscular Dystrophy

Neuropathy

Alzheimerrsquos and Mild Cognitive Impairment

Stroke Recovery and Brain Injury

Partial Spinal Cord Injuries

ALS

Retinitis pigmentosa

Age related- dry type- Macular Degeneration

Fortify fat grafts for better survival Face breasts buttocks hands etc

May be able to treat and improve skin quality

May be able to delay aging by adding to existing

fat

SVF alone

SVF with Neograft follicle transfer hair transplantation

Neograft alone

By far the most common type of hair restoration procedure

Involves surgery to the back of the scalp that results in a large scar

The scar will be visible with short hair Significant downtime and pain Typically good results

CRITICAL LIMB ISCHEMIA

WOUND CARE

TMJ SYNDROME

LICHEN SCLEROSIS

ANTI-AGEING

Over 300 cases with one complication

No documented cases of serious injury in human

or animals

International Stem Cell Society (ISCS) ndash reported

over 1000 registered cases Less than 2 complications of any kind

No serious adverse events

Depends on condition being treated

In 2013- we can cryopreserve cells for future use

Active Cancer

Infection

Blood Thinners

Use patients own cells

Provide service during same operative procedure

Minimally manipulate cells

Do not promote therapy or make claims

Performed as a surgical procedure (no laboratory)

Need IRB approved (FDA registered) studies to

support valid claims

International Centers (variably reputable)

Research meetings

Anecdotal and testimonial information

Early results from clinical trials

Veterinary literature

Personal experience with our own patients in USA

(more than 300)

UNIVERSITYPHARMA LABS

FDA APPROVED TRIALS

MOSTLY BONE MARROW AND

SOME EMBRYONIC

LONG TIME FOR OUTCOMES

PATENT ISSUES

FOR INSTITUTIONAL

PROFITGOVT FUNDED

DRUG MODEL

GRASSROOTS COMMUNITY

PHYSICIANrsquoS PRACTICE

BONE MARROW AND ADIPOSE

DERIVED

RAPID CLINICAL EVALUATION

WIDESPREAD AVAILABILITY

NO PATENTS NEEDED

FOR PROFITPATIENT FUNDED

NOT ldquoDRUG ORIENTEDrdquo

CSN In Association with theCalifornia Stem Cell Treatment Center

International research sharing protocols and database including Asia and Canada

High numbers of fresh autologous cells for various degenerative conditions

Standardized Multispecialty care

Advanced deployment methods

Quality Stem Cell Therapy should be available everywhere and easily accessible

WWWSTEMCELLREVOLUTIONCOM

After Three Months

Wanted to share with you the news

I was just released from my eye therapy

I am still waiting on the prism sticker for

my glasses but no more eye patch

After Four Months

I am doing GREAT I have full

vision back and havenrsquot taken my

MS shots since January

After Five Months

This is one Happy Girl

Just left my neurologist and no signs of MS for this Girl

Indiana Stem Cell Treatment CenterDr Robert F Jackson amp Dr Chris Lowery

9660 East 146th Street Suite 100

Noblesville IN 46060

317-773-6677 or 800-708-2462

wwwindianastemcelltreatmentcentercom

Thank you for your Attention

Dormant if no tissue damage or injury

They respond to tissue injury inflammation

degeneration or cell death

Tissue damage-homing properties

Cells may turn into needed tissue

Cells may provide messaging through Growth

Factors (eg cytokines) to repair damaged cells

Stem cell BIOAVAILABILITY- dormant cells

made available to damaged tissue

When additional stem cells are added to injured

areas in large numbers they can effect therapeutic

changes

Can exert local and systemic changes

New equipment and enzymes

Adipose (fat) derived stem cells are easy to harvest

Safe ndash under local anesthesia

Safe ndash Autologous (your own cells)

Abundant numbers of cells

Procedure takes 3 hours total

PART OF FAT RICH IN ADULT MESENCHYMAL STEM CELLS AND NATURAL GROWTH FACTORS

WHAT WE DEPLOY AT CALIFORNIA STEM CELL TREATMENT CENTERreg

Harvest fat under local anesthesia

Centrifuge to concentrate the fat

Add an enzyme to digest collagen tissue that binds

fat cells and stem cells

Remove stem cells (stromal vascular fraction) from bottom of syringe ndash ldquoclosed (sterile) techniquerdquo

SVF PROCUREMENT TAKES 80 MINUTES

Stemprogenitor cells

Direct injections into affected arthritic joints

Injection into difficult areas via fluoroscopy

Intravenous injection to affect systemic changes

Injection into spinal fluid or other remote areas

Directly into arteries of body or brain

Directly into soft tissues showing damage

SVF IS REGENERATIVE

SVF IS ANTI-INFLAMMATORY

SVF IS IMMUNO-MODULATORY

Orthopedics

Degenerative Diseases

Cardio-Pulmonary Diseases

Autoimmune Diseases

Urology

Neurology

Cosmetic Surgery

Spinal disk Arthritis and Chronic back or neck pain

Ankle

Hip

Knee

Tendons Ligaments Sports Injuries

Elbow Wrist

Shoulder

Prior to SVF deployment4 months after SVF deployment

End Stage CHF

Ischemic Cardiomyopathy

Acute MI

AsthmaRestrictive Lung Disease

COPDEMPHYSEMA

Not Pulmonary Fibrosis

FIBROMYALGIA

SCLERODERMA

POLYCHONDITIS

CIDP

MYASTHENIA GRAVIS

RHEUMATOID ARTHRITIS

CROHNS DISEASE

AUTO-IMMUNE HEPATITIS

RELAPSING POLYCHONDRITIS

ALOPECIA AREATA

OPTIC NEURITIS

Interstitial Cystitis

Peyronies Disease

Post prostatectomy Incontinence

Erectile Dysfunction

Int J Urol 2010 Oct17(10)896

Yamamoto T Gotoh M Hattori R Toriyama K Kamei Y Iwaguro H Matsukawa Y Funahashi Y

Periurethral injection of autologous adipose-derived stem cells for the treatment of stress urinary incontinence in patients undergoing radical prostatectomy report of two initial cases

2006

130 (45 men and 85 women with leakage)

Myoblasts (muscle stem cells) used

111 cured 17 more improved

Males 73 improved

Ultrasonography and magnetic resonance imaging showed sustained presence of the injected adipose tissue

Enhanced ultrasonography showed a progressive increase in the blood flow to the injected area

Enhanced ultrasonography showed a progressive increase in the blood flow to the injected area

Japanese protocol

Sphincteric injection of fat and SVF into muscle

Injected through scope under local anesthesia

Parkinsonrsquos

Multiple Sclerosis

Muscular Dystrophy

Neuropathy

Alzheimerrsquos and Mild Cognitive Impairment

Stroke Recovery and Brain Injury

Partial Spinal Cord Injuries

ALS

Retinitis pigmentosa

Age related- dry type- Macular Degeneration

Fortify fat grafts for better survival Face breasts buttocks hands etc

May be able to treat and improve skin quality

May be able to delay aging by adding to existing

fat

SVF alone

SVF with Neograft follicle transfer hair transplantation

Neograft alone

By far the most common type of hair restoration procedure

Involves surgery to the back of the scalp that results in a large scar

The scar will be visible with short hair Significant downtime and pain Typically good results

CRITICAL LIMB ISCHEMIA

WOUND CARE

TMJ SYNDROME

LICHEN SCLEROSIS

ANTI-AGEING

Over 300 cases with one complication

No documented cases of serious injury in human

or animals

International Stem Cell Society (ISCS) ndash reported

over 1000 registered cases Less than 2 complications of any kind

No serious adverse events

Depends on condition being treated

In 2013- we can cryopreserve cells for future use

Active Cancer

Infection

Blood Thinners

Use patients own cells

Provide service during same operative procedure

Minimally manipulate cells

Do not promote therapy or make claims

Performed as a surgical procedure (no laboratory)

Need IRB approved (FDA registered) studies to

support valid claims

International Centers (variably reputable)

Research meetings

Anecdotal and testimonial information

Early results from clinical trials

Veterinary literature

Personal experience with our own patients in USA

(more than 300)

UNIVERSITYPHARMA LABS

FDA APPROVED TRIALS

MOSTLY BONE MARROW AND

SOME EMBRYONIC

LONG TIME FOR OUTCOMES

PATENT ISSUES

FOR INSTITUTIONAL

PROFITGOVT FUNDED

DRUG MODEL

GRASSROOTS COMMUNITY

PHYSICIANrsquoS PRACTICE

BONE MARROW AND ADIPOSE

DERIVED

RAPID CLINICAL EVALUATION

WIDESPREAD AVAILABILITY

NO PATENTS NEEDED

FOR PROFITPATIENT FUNDED

NOT ldquoDRUG ORIENTEDrdquo

CSN In Association with theCalifornia Stem Cell Treatment Center

International research sharing protocols and database including Asia and Canada

High numbers of fresh autologous cells for various degenerative conditions

Standardized Multispecialty care

Advanced deployment methods

Quality Stem Cell Therapy should be available everywhere and easily accessible

WWWSTEMCELLREVOLUTIONCOM

After Three Months

Wanted to share with you the news

I was just released from my eye therapy

I am still waiting on the prism sticker for

my glasses but no more eye patch

After Four Months

I am doing GREAT I have full

vision back and havenrsquot taken my

MS shots since January

After Five Months

This is one Happy Girl

Just left my neurologist and no signs of MS for this Girl

Indiana Stem Cell Treatment CenterDr Robert F Jackson amp Dr Chris Lowery

9660 East 146th Street Suite 100

Noblesville IN 46060

317-773-6677 or 800-708-2462

wwwindianastemcelltreatmentcentercom

Thank you for your Attention

Stem cell BIOAVAILABILITY- dormant cells

made available to damaged tissue

When additional stem cells are added to injured

areas in large numbers they can effect therapeutic

changes

Can exert local and systemic changes

New equipment and enzymes

Adipose (fat) derived stem cells are easy to harvest

Safe ndash under local anesthesia

Safe ndash Autologous (your own cells)

Abundant numbers of cells

Procedure takes 3 hours total

PART OF FAT RICH IN ADULT MESENCHYMAL STEM CELLS AND NATURAL GROWTH FACTORS

WHAT WE DEPLOY AT CALIFORNIA STEM CELL TREATMENT CENTERreg

Harvest fat under local anesthesia

Centrifuge to concentrate the fat

Add an enzyme to digest collagen tissue that binds

fat cells and stem cells

Remove stem cells (stromal vascular fraction) from bottom of syringe ndash ldquoclosed (sterile) techniquerdquo

SVF PROCUREMENT TAKES 80 MINUTES

Stemprogenitor cells

Direct injections into affected arthritic joints

Injection into difficult areas via fluoroscopy

Intravenous injection to affect systemic changes

Injection into spinal fluid or other remote areas

Directly into arteries of body or brain

Directly into soft tissues showing damage

SVF IS REGENERATIVE

SVF IS ANTI-INFLAMMATORY

SVF IS IMMUNO-MODULATORY

Orthopedics

Degenerative Diseases

Cardio-Pulmonary Diseases

Autoimmune Diseases

Urology

Neurology

Cosmetic Surgery

Spinal disk Arthritis and Chronic back or neck pain

Ankle

Hip

Knee

Tendons Ligaments Sports Injuries

Elbow Wrist

Shoulder

Prior to SVF deployment4 months after SVF deployment

End Stage CHF

Ischemic Cardiomyopathy

Acute MI

AsthmaRestrictive Lung Disease

COPDEMPHYSEMA

Not Pulmonary Fibrosis

FIBROMYALGIA

SCLERODERMA

POLYCHONDITIS

CIDP

MYASTHENIA GRAVIS

RHEUMATOID ARTHRITIS

CROHNS DISEASE

AUTO-IMMUNE HEPATITIS

RELAPSING POLYCHONDRITIS

ALOPECIA AREATA

OPTIC NEURITIS

Interstitial Cystitis

Peyronies Disease

Post prostatectomy Incontinence

Erectile Dysfunction

Int J Urol 2010 Oct17(10)896

Yamamoto T Gotoh M Hattori R Toriyama K Kamei Y Iwaguro H Matsukawa Y Funahashi Y

Periurethral injection of autologous adipose-derived stem cells for the treatment of stress urinary incontinence in patients undergoing radical prostatectomy report of two initial cases

2006

130 (45 men and 85 women with leakage)

Myoblasts (muscle stem cells) used

111 cured 17 more improved

Males 73 improved

Ultrasonography and magnetic resonance imaging showed sustained presence of the injected adipose tissue

Enhanced ultrasonography showed a progressive increase in the blood flow to the injected area

Enhanced ultrasonography showed a progressive increase in the blood flow to the injected area

Japanese protocol

Sphincteric injection of fat and SVF into muscle

Injected through scope under local anesthesia

Parkinsonrsquos

Multiple Sclerosis

Muscular Dystrophy

Neuropathy

Alzheimerrsquos and Mild Cognitive Impairment

Stroke Recovery and Brain Injury

Partial Spinal Cord Injuries

ALS

Retinitis pigmentosa

Age related- dry type- Macular Degeneration

Fortify fat grafts for better survival Face breasts buttocks hands etc

May be able to treat and improve skin quality

May be able to delay aging by adding to existing

fat

SVF alone

SVF with Neograft follicle transfer hair transplantation

Neograft alone

By far the most common type of hair restoration procedure

Involves surgery to the back of the scalp that results in a large scar

The scar will be visible with short hair Significant downtime and pain Typically good results

CRITICAL LIMB ISCHEMIA

WOUND CARE

TMJ SYNDROME

LICHEN SCLEROSIS

ANTI-AGEING

Over 300 cases with one complication

No documented cases of serious injury in human

or animals

International Stem Cell Society (ISCS) ndash reported

over 1000 registered cases Less than 2 complications of any kind

No serious adverse events

Depends on condition being treated

In 2013- we can cryopreserve cells for future use

Active Cancer

Infection

Blood Thinners

Use patients own cells

Provide service during same operative procedure

Minimally manipulate cells

Do not promote therapy or make claims

Performed as a surgical procedure (no laboratory)

Need IRB approved (FDA registered) studies to

support valid claims

International Centers (variably reputable)

Research meetings

Anecdotal and testimonial information

Early results from clinical trials

Veterinary literature

Personal experience with our own patients in USA

(more than 300)

UNIVERSITYPHARMA LABS

FDA APPROVED TRIALS

MOSTLY BONE MARROW AND

SOME EMBRYONIC

LONG TIME FOR OUTCOMES

PATENT ISSUES

FOR INSTITUTIONAL

PROFITGOVT FUNDED

DRUG MODEL

GRASSROOTS COMMUNITY

PHYSICIANrsquoS PRACTICE

BONE MARROW AND ADIPOSE

DERIVED

RAPID CLINICAL EVALUATION

WIDESPREAD AVAILABILITY

NO PATENTS NEEDED

FOR PROFITPATIENT FUNDED

NOT ldquoDRUG ORIENTEDrdquo

CSN In Association with theCalifornia Stem Cell Treatment Center

International research sharing protocols and database including Asia and Canada

High numbers of fresh autologous cells for various degenerative conditions

Standardized Multispecialty care

Advanced deployment methods

Quality Stem Cell Therapy should be available everywhere and easily accessible

WWWSTEMCELLREVOLUTIONCOM

After Three Months

Wanted to share with you the news

I was just released from my eye therapy

I am still waiting on the prism sticker for

my glasses but no more eye patch

After Four Months

I am doing GREAT I have full

vision back and havenrsquot taken my

MS shots since January

After Five Months

This is one Happy Girl

Just left my neurologist and no signs of MS for this Girl

Indiana Stem Cell Treatment CenterDr Robert F Jackson amp Dr Chris Lowery

9660 East 146th Street Suite 100

Noblesville IN 46060

317-773-6677 or 800-708-2462

wwwindianastemcelltreatmentcentercom

Thank you for your Attention

New equipment and enzymes

Adipose (fat) derived stem cells are easy to harvest

Safe ndash under local anesthesia

Safe ndash Autologous (your own cells)

Abundant numbers of cells

Procedure takes 3 hours total

PART OF FAT RICH IN ADULT MESENCHYMAL STEM CELLS AND NATURAL GROWTH FACTORS

WHAT WE DEPLOY AT CALIFORNIA STEM CELL TREATMENT CENTERreg

Harvest fat under local anesthesia

Centrifuge to concentrate the fat

Add an enzyme to digest collagen tissue that binds

fat cells and stem cells

Remove stem cells (stromal vascular fraction) from bottom of syringe ndash ldquoclosed (sterile) techniquerdquo

SVF PROCUREMENT TAKES 80 MINUTES

Stemprogenitor cells

Direct injections into affected arthritic joints

Injection into difficult areas via fluoroscopy

Intravenous injection to affect systemic changes

Injection into spinal fluid or other remote areas

Directly into arteries of body or brain

Directly into soft tissues showing damage

SVF IS REGENERATIVE

SVF IS ANTI-INFLAMMATORY

SVF IS IMMUNO-MODULATORY

Orthopedics

Degenerative Diseases

Cardio-Pulmonary Diseases

Autoimmune Diseases

Urology

Neurology

Cosmetic Surgery

Spinal disk Arthritis and Chronic back or neck pain

Ankle

Hip

Knee

Tendons Ligaments Sports Injuries

Elbow Wrist

Shoulder

Prior to SVF deployment4 months after SVF deployment

End Stage CHF

Ischemic Cardiomyopathy

Acute MI

AsthmaRestrictive Lung Disease

COPDEMPHYSEMA

Not Pulmonary Fibrosis

FIBROMYALGIA

SCLERODERMA

POLYCHONDITIS

CIDP

MYASTHENIA GRAVIS

RHEUMATOID ARTHRITIS

CROHNS DISEASE

AUTO-IMMUNE HEPATITIS

RELAPSING POLYCHONDRITIS

ALOPECIA AREATA

OPTIC NEURITIS

Interstitial Cystitis

Peyronies Disease

Post prostatectomy Incontinence

Erectile Dysfunction

Int J Urol 2010 Oct17(10)896

Yamamoto T Gotoh M Hattori R Toriyama K Kamei Y Iwaguro H Matsukawa Y Funahashi Y

Periurethral injection of autologous adipose-derived stem cells for the treatment of stress urinary incontinence in patients undergoing radical prostatectomy report of two initial cases

2006

130 (45 men and 85 women with leakage)

Myoblasts (muscle stem cells) used

111 cured 17 more improved

Males 73 improved

Ultrasonography and magnetic resonance imaging showed sustained presence of the injected adipose tissue

Enhanced ultrasonography showed a progressive increase in the blood flow to the injected area

Enhanced ultrasonography showed a progressive increase in the blood flow to the injected area

Japanese protocol

Sphincteric injection of fat and SVF into muscle

Injected through scope under local anesthesia

Parkinsonrsquos

Multiple Sclerosis

Muscular Dystrophy

Neuropathy

Alzheimerrsquos and Mild Cognitive Impairment

Stroke Recovery and Brain Injury

Partial Spinal Cord Injuries

ALS

Retinitis pigmentosa

Age related- dry type- Macular Degeneration

Fortify fat grafts for better survival Face breasts buttocks hands etc

May be able to treat and improve skin quality

May be able to delay aging by adding to existing

fat

SVF alone

SVF with Neograft follicle transfer hair transplantation

Neograft alone

By far the most common type of hair restoration procedure

Involves surgery to the back of the scalp that results in a large scar

The scar will be visible with short hair Significant downtime and pain Typically good results

CRITICAL LIMB ISCHEMIA

WOUND CARE

TMJ SYNDROME

LICHEN SCLEROSIS

ANTI-AGEING

Over 300 cases with one complication

No documented cases of serious injury in human

or animals

International Stem Cell Society (ISCS) ndash reported

over 1000 registered cases Less than 2 complications of any kind

No serious adverse events

Depends on condition being treated

In 2013- we can cryopreserve cells for future use

Active Cancer

Infection

Blood Thinners

Use patients own cells

Provide service during same operative procedure

Minimally manipulate cells

Do not promote therapy or make claims

Performed as a surgical procedure (no laboratory)

Need IRB approved (FDA registered) studies to

support valid claims

International Centers (variably reputable)

Research meetings

Anecdotal and testimonial information

Early results from clinical trials

Veterinary literature

Personal experience with our own patients in USA

(more than 300)

UNIVERSITYPHARMA LABS

FDA APPROVED TRIALS

MOSTLY BONE MARROW AND

SOME EMBRYONIC

LONG TIME FOR OUTCOMES

PATENT ISSUES

FOR INSTITUTIONAL

PROFITGOVT FUNDED

DRUG MODEL

GRASSROOTS COMMUNITY

PHYSICIANrsquoS PRACTICE

BONE MARROW AND ADIPOSE

DERIVED

RAPID CLINICAL EVALUATION

WIDESPREAD AVAILABILITY

NO PATENTS NEEDED

FOR PROFITPATIENT FUNDED

NOT ldquoDRUG ORIENTEDrdquo

CSN In Association with theCalifornia Stem Cell Treatment Center

International research sharing protocols and database including Asia and Canada

High numbers of fresh autologous cells for various degenerative conditions

Standardized Multispecialty care

Advanced deployment methods

Quality Stem Cell Therapy should be available everywhere and easily accessible

WWWSTEMCELLREVOLUTIONCOM

After Three Months

Wanted to share with you the news

I was just released from my eye therapy

I am still waiting on the prism sticker for

my glasses but no more eye patch

After Four Months

I am doing GREAT I have full

vision back and havenrsquot taken my

MS shots since January

After Five Months

This is one Happy Girl

Just left my neurologist and no signs of MS for this Girl

Indiana Stem Cell Treatment CenterDr Robert F Jackson amp Dr Chris Lowery

9660 East 146th Street Suite 100

Noblesville IN 46060

317-773-6677 or 800-708-2462

wwwindianastemcelltreatmentcentercom

Thank you for your Attention

PART OF FAT RICH IN ADULT MESENCHYMAL STEM CELLS AND NATURAL GROWTH FACTORS

WHAT WE DEPLOY AT CALIFORNIA STEM CELL TREATMENT CENTERreg

Harvest fat under local anesthesia

Centrifuge to concentrate the fat

Add an enzyme to digest collagen tissue that binds

fat cells and stem cells

Remove stem cells (stromal vascular fraction) from bottom of syringe ndash ldquoclosed (sterile) techniquerdquo

SVF PROCUREMENT TAKES 80 MINUTES

Stemprogenitor cells

Direct injections into affected arthritic joints

Injection into difficult areas via fluoroscopy

Intravenous injection to affect systemic changes

Injection into spinal fluid or other remote areas

Directly into arteries of body or brain

Directly into soft tissues showing damage

SVF IS REGENERATIVE

SVF IS ANTI-INFLAMMATORY

SVF IS IMMUNO-MODULATORY

Orthopedics

Degenerative Diseases

Cardio-Pulmonary Diseases

Autoimmune Diseases

Urology

Neurology

Cosmetic Surgery

Spinal disk Arthritis and Chronic back or neck pain

Ankle

Hip

Knee

Tendons Ligaments Sports Injuries

Elbow Wrist

Shoulder

Prior to SVF deployment4 months after SVF deployment

End Stage CHF

Ischemic Cardiomyopathy

Acute MI

AsthmaRestrictive Lung Disease

COPDEMPHYSEMA

Not Pulmonary Fibrosis

FIBROMYALGIA

SCLERODERMA

POLYCHONDITIS

CIDP

MYASTHENIA GRAVIS

RHEUMATOID ARTHRITIS

CROHNS DISEASE

AUTO-IMMUNE HEPATITIS

RELAPSING POLYCHONDRITIS

ALOPECIA AREATA

OPTIC NEURITIS

Interstitial Cystitis

Peyronies Disease

Post prostatectomy Incontinence

Erectile Dysfunction

Int J Urol 2010 Oct17(10)896

Yamamoto T Gotoh M Hattori R Toriyama K Kamei Y Iwaguro H Matsukawa Y Funahashi Y

Periurethral injection of autologous adipose-derived stem cells for the treatment of stress urinary incontinence in patients undergoing radical prostatectomy report of two initial cases

2006

130 (45 men and 85 women with leakage)

Myoblasts (muscle stem cells) used

111 cured 17 more improved

Males 73 improved

Ultrasonography and magnetic resonance imaging showed sustained presence of the injected adipose tissue

Enhanced ultrasonography showed a progressive increase in the blood flow to the injected area

Enhanced ultrasonography showed a progressive increase in the blood flow to the injected area

Japanese protocol

Sphincteric injection of fat and SVF into muscle

Injected through scope under local anesthesia

Parkinsonrsquos

Multiple Sclerosis

Muscular Dystrophy

Neuropathy

Alzheimerrsquos and Mild Cognitive Impairment

Stroke Recovery and Brain Injury

Partial Spinal Cord Injuries

ALS

Retinitis pigmentosa

Age related- dry type- Macular Degeneration

Fortify fat grafts for better survival Face breasts buttocks hands etc

May be able to treat and improve skin quality

May be able to delay aging by adding to existing

fat

SVF alone

SVF with Neograft follicle transfer hair transplantation

Neograft alone

By far the most common type of hair restoration procedure

Involves surgery to the back of the scalp that results in a large scar

The scar will be visible with short hair Significant downtime and pain Typically good results

CRITICAL LIMB ISCHEMIA

WOUND CARE

TMJ SYNDROME

LICHEN SCLEROSIS

ANTI-AGEING

Over 300 cases with one complication

No documented cases of serious injury in human

or animals

International Stem Cell Society (ISCS) ndash reported

over 1000 registered cases Less than 2 complications of any kind

No serious adverse events

Depends on condition being treated

In 2013- we can cryopreserve cells for future use

Active Cancer

Infection

Blood Thinners

Use patients own cells

Provide service during same operative procedure

Minimally manipulate cells

Do not promote therapy or make claims

Performed as a surgical procedure (no laboratory)

Need IRB approved (FDA registered) studies to

support valid claims

International Centers (variably reputable)

Research meetings

Anecdotal and testimonial information

Early results from clinical trials

Veterinary literature

Personal experience with our own patients in USA

(more than 300)

UNIVERSITYPHARMA LABS

FDA APPROVED TRIALS

MOSTLY BONE MARROW AND

SOME EMBRYONIC

LONG TIME FOR OUTCOMES

PATENT ISSUES

FOR INSTITUTIONAL

PROFITGOVT FUNDED

DRUG MODEL

GRASSROOTS COMMUNITY

PHYSICIANrsquoS PRACTICE

BONE MARROW AND ADIPOSE

DERIVED

RAPID CLINICAL EVALUATION

WIDESPREAD AVAILABILITY

NO PATENTS NEEDED

FOR PROFITPATIENT FUNDED

NOT ldquoDRUG ORIENTEDrdquo

CSN In Association with theCalifornia Stem Cell Treatment Center

International research sharing protocols and database including Asia and Canada

High numbers of fresh autologous cells for various degenerative conditions

Standardized Multispecialty care

Advanced deployment methods

Quality Stem Cell Therapy should be available everywhere and easily accessible

WWWSTEMCELLREVOLUTIONCOM

After Three Months

Wanted to share with you the news

I was just released from my eye therapy

I am still waiting on the prism sticker for

my glasses but no more eye patch

After Four Months

I am doing GREAT I have full

vision back and havenrsquot taken my

MS shots since January

After Five Months

This is one Happy Girl

Just left my neurologist and no signs of MS for this Girl

Indiana Stem Cell Treatment CenterDr Robert F Jackson amp Dr Chris Lowery

9660 East 146th Street Suite 100

Noblesville IN 46060

317-773-6677 or 800-708-2462

wwwindianastemcelltreatmentcentercom

Thank you for your Attention

Harvest fat under local anesthesia

Centrifuge to concentrate the fat

Add an enzyme to digest collagen tissue that binds

fat cells and stem cells

Remove stem cells (stromal vascular fraction) from bottom of syringe ndash ldquoclosed (sterile) techniquerdquo

SVF PROCUREMENT TAKES 80 MINUTES

Stemprogenitor cells

Direct injections into affected arthritic joints

Injection into difficult areas via fluoroscopy

Intravenous injection to affect systemic changes

Injection into spinal fluid or other remote areas

Directly into arteries of body or brain

Directly into soft tissues showing damage

SVF IS REGENERATIVE

SVF IS ANTI-INFLAMMATORY

SVF IS IMMUNO-MODULATORY

Orthopedics

Degenerative Diseases

Cardio-Pulmonary Diseases

Autoimmune Diseases

Urology

Neurology

Cosmetic Surgery

Spinal disk Arthritis and Chronic back or neck pain

Ankle

Hip

Knee

Tendons Ligaments Sports Injuries

Elbow Wrist

Shoulder

Prior to SVF deployment4 months after SVF deployment

End Stage CHF

Ischemic Cardiomyopathy

Acute MI

AsthmaRestrictive Lung Disease

COPDEMPHYSEMA

Not Pulmonary Fibrosis

FIBROMYALGIA

SCLERODERMA

POLYCHONDITIS

CIDP

MYASTHENIA GRAVIS

RHEUMATOID ARTHRITIS

CROHNS DISEASE

AUTO-IMMUNE HEPATITIS

RELAPSING POLYCHONDRITIS

ALOPECIA AREATA

OPTIC NEURITIS

Interstitial Cystitis

Peyronies Disease

Post prostatectomy Incontinence

Erectile Dysfunction

Int J Urol 2010 Oct17(10)896

Yamamoto T Gotoh M Hattori R Toriyama K Kamei Y Iwaguro H Matsukawa Y Funahashi Y

Periurethral injection of autologous adipose-derived stem cells for the treatment of stress urinary incontinence in patients undergoing radical prostatectomy report of two initial cases

2006

130 (45 men and 85 women with leakage)

Myoblasts (muscle stem cells) used

111 cured 17 more improved

Males 73 improved

Ultrasonography and magnetic resonance imaging showed sustained presence of the injected adipose tissue

Enhanced ultrasonography showed a progressive increase in the blood flow to the injected area

Enhanced ultrasonography showed a progressive increase in the blood flow to the injected area

Japanese protocol

Sphincteric injection of fat and SVF into muscle

Injected through scope under local anesthesia

Parkinsonrsquos

Multiple Sclerosis

Muscular Dystrophy

Neuropathy

Alzheimerrsquos and Mild Cognitive Impairment

Stroke Recovery and Brain Injury

Partial Spinal Cord Injuries

ALS

Retinitis pigmentosa

Age related- dry type- Macular Degeneration

Fortify fat grafts for better survival Face breasts buttocks hands etc

May be able to treat and improve skin quality

May be able to delay aging by adding to existing

fat

SVF alone

SVF with Neograft follicle transfer hair transplantation

Neograft alone

By far the most common type of hair restoration procedure

Involves surgery to the back of the scalp that results in a large scar

The scar will be visible with short hair Significant downtime and pain Typically good results

CRITICAL LIMB ISCHEMIA

WOUND CARE

TMJ SYNDROME

LICHEN SCLEROSIS

ANTI-AGEING

Over 300 cases with one complication

No documented cases of serious injury in human

or animals

International Stem Cell Society (ISCS) ndash reported

over 1000 registered cases Less than 2 complications of any kind

No serious adverse events

Depends on condition being treated

In 2013- we can cryopreserve cells for future use

Active Cancer

Infection

Blood Thinners

Use patients own cells

Provide service during same operative procedure

Minimally manipulate cells

Do not promote therapy or make claims

Performed as a surgical procedure (no laboratory)

Need IRB approved (FDA registered) studies to

support valid claims

International Centers (variably reputable)

Research meetings

Anecdotal and testimonial information

Early results from clinical trials

Veterinary literature

Personal experience with our own patients in USA

(more than 300)

UNIVERSITYPHARMA LABS

FDA APPROVED TRIALS

MOSTLY BONE MARROW AND

SOME EMBRYONIC

LONG TIME FOR OUTCOMES

PATENT ISSUES

FOR INSTITUTIONAL

PROFITGOVT FUNDED

DRUG MODEL

GRASSROOTS COMMUNITY

PHYSICIANrsquoS PRACTICE

BONE MARROW AND ADIPOSE

DERIVED

RAPID CLINICAL EVALUATION

WIDESPREAD AVAILABILITY

NO PATENTS NEEDED

FOR PROFITPATIENT FUNDED

NOT ldquoDRUG ORIENTEDrdquo

CSN In Association with theCalifornia Stem Cell Treatment Center

International research sharing protocols and database including Asia and Canada

High numbers of fresh autologous cells for various degenerative conditions

Standardized Multispecialty care

Advanced deployment methods

Quality Stem Cell Therapy should be available everywhere and easily accessible

WWWSTEMCELLREVOLUTIONCOM

After Three Months

Wanted to share with you the news

I was just released from my eye therapy

I am still waiting on the prism sticker for

my glasses but no more eye patch

After Four Months

I am doing GREAT I have full

vision back and havenrsquot taken my

MS shots since January

After Five Months

This is one Happy Girl

Just left my neurologist and no signs of MS for this Girl

Indiana Stem Cell Treatment CenterDr Robert F Jackson amp Dr Chris Lowery

9660 East 146th Street Suite 100

Noblesville IN 46060

317-773-6677 or 800-708-2462

wwwindianastemcelltreatmentcentercom

Thank you for your Attention

SVF PROCUREMENT TAKES 80 MINUTES

Stemprogenitor cells

Direct injections into affected arthritic joints

Injection into difficult areas via fluoroscopy

Intravenous injection to affect systemic changes

Injection into spinal fluid or other remote areas

Directly into arteries of body or brain

Directly into soft tissues showing damage

SVF IS REGENERATIVE

SVF IS ANTI-INFLAMMATORY

SVF IS IMMUNO-MODULATORY

Orthopedics

Degenerative Diseases

Cardio-Pulmonary Diseases

Autoimmune Diseases

Urology

Neurology

Cosmetic Surgery

Spinal disk Arthritis and Chronic back or neck pain

Ankle

Hip

Knee

Tendons Ligaments Sports Injuries

Elbow Wrist

Shoulder

Prior to SVF deployment4 months after SVF deployment

End Stage CHF

Ischemic Cardiomyopathy

Acute MI

AsthmaRestrictive Lung Disease

COPDEMPHYSEMA

Not Pulmonary Fibrosis

FIBROMYALGIA

SCLERODERMA

POLYCHONDITIS

CIDP

MYASTHENIA GRAVIS

RHEUMATOID ARTHRITIS

CROHNS DISEASE

AUTO-IMMUNE HEPATITIS

RELAPSING POLYCHONDRITIS

ALOPECIA AREATA

OPTIC NEURITIS

Interstitial Cystitis

Peyronies Disease

Post prostatectomy Incontinence

Erectile Dysfunction

Int J Urol 2010 Oct17(10)896

Yamamoto T Gotoh M Hattori R Toriyama K Kamei Y Iwaguro H Matsukawa Y Funahashi Y

Periurethral injection of autologous adipose-derived stem cells for the treatment of stress urinary incontinence in patients undergoing radical prostatectomy report of two initial cases

2006

130 (45 men and 85 women with leakage)

Myoblasts (muscle stem cells) used

111 cured 17 more improved

Males 73 improved

Ultrasonography and magnetic resonance imaging showed sustained presence of the injected adipose tissue

Enhanced ultrasonography showed a progressive increase in the blood flow to the injected area

Enhanced ultrasonography showed a progressive increase in the blood flow to the injected area

Japanese protocol

Sphincteric injection of fat and SVF into muscle

Injected through scope under local anesthesia

Parkinsonrsquos

Multiple Sclerosis

Muscular Dystrophy

Neuropathy

Alzheimerrsquos and Mild Cognitive Impairment

Stroke Recovery and Brain Injury

Partial Spinal Cord Injuries

ALS

Retinitis pigmentosa

Age related- dry type- Macular Degeneration

Fortify fat grafts for better survival Face breasts buttocks hands etc

May be able to treat and improve skin quality

May be able to delay aging by adding to existing

fat

SVF alone

SVF with Neograft follicle transfer hair transplantation

Neograft alone

By far the most common type of hair restoration procedure

Involves surgery to the back of the scalp that results in a large scar

The scar will be visible with short hair Significant downtime and pain Typically good results

CRITICAL LIMB ISCHEMIA

WOUND CARE

TMJ SYNDROME

LICHEN SCLEROSIS

ANTI-AGEING

Over 300 cases with one complication

No documented cases of serious injury in human

or animals

International Stem Cell Society (ISCS) ndash reported

over 1000 registered cases Less than 2 complications of any kind

No serious adverse events

Depends on condition being treated

In 2013- we can cryopreserve cells for future use

Active Cancer

Infection

Blood Thinners

Use patients own cells

Provide service during same operative procedure

Minimally manipulate cells

Do not promote therapy or make claims

Performed as a surgical procedure (no laboratory)

Need IRB approved (FDA registered) studies to

support valid claims

International Centers (variably reputable)

Research meetings

Anecdotal and testimonial information

Early results from clinical trials

Veterinary literature

Personal experience with our own patients in USA

(more than 300)

UNIVERSITYPHARMA LABS

FDA APPROVED TRIALS

MOSTLY BONE MARROW AND

SOME EMBRYONIC

LONG TIME FOR OUTCOMES

PATENT ISSUES

FOR INSTITUTIONAL

PROFITGOVT FUNDED

DRUG MODEL

GRASSROOTS COMMUNITY

PHYSICIANrsquoS PRACTICE

BONE MARROW AND ADIPOSE

DERIVED

RAPID CLINICAL EVALUATION

WIDESPREAD AVAILABILITY

NO PATENTS NEEDED

FOR PROFITPATIENT FUNDED

NOT ldquoDRUG ORIENTEDrdquo

CSN In Association with theCalifornia Stem Cell Treatment Center

International research sharing protocols and database including Asia and Canada

High numbers of fresh autologous cells for various degenerative conditions

Standardized Multispecialty care

Advanced deployment methods

Quality Stem Cell Therapy should be available everywhere and easily accessible

WWWSTEMCELLREVOLUTIONCOM

After Three Months

Wanted to share with you the news

I was just released from my eye therapy

I am still waiting on the prism sticker for

my glasses but no more eye patch

After Four Months

I am doing GREAT I have full

vision back and havenrsquot taken my

MS shots since January

After Five Months

This is one Happy Girl

Just left my neurologist and no signs of MS for this Girl

Indiana Stem Cell Treatment CenterDr Robert F Jackson amp Dr Chris Lowery

9660 East 146th Street Suite 100

Noblesville IN 46060

317-773-6677 or 800-708-2462

wwwindianastemcelltreatmentcentercom

Thank you for your Attention

Stemprogenitor cells

Direct injections into affected arthritic joints

Injection into difficult areas via fluoroscopy

Intravenous injection to affect systemic changes

Injection into spinal fluid or other remote areas

Directly into arteries of body or brain

Directly into soft tissues showing damage

SVF IS REGENERATIVE

SVF IS ANTI-INFLAMMATORY

SVF IS IMMUNO-MODULATORY

Orthopedics

Degenerative Diseases

Cardio-Pulmonary Diseases

Autoimmune Diseases

Urology

Neurology

Cosmetic Surgery

Spinal disk Arthritis and Chronic back or neck pain

Ankle

Hip

Knee

Tendons Ligaments Sports Injuries

Elbow Wrist

Shoulder

Prior to SVF deployment4 months after SVF deployment

End Stage CHF

Ischemic Cardiomyopathy

Acute MI

AsthmaRestrictive Lung Disease

COPDEMPHYSEMA

Not Pulmonary Fibrosis

FIBROMYALGIA

SCLERODERMA

POLYCHONDITIS

CIDP

MYASTHENIA GRAVIS

RHEUMATOID ARTHRITIS

CROHNS DISEASE

AUTO-IMMUNE HEPATITIS

RELAPSING POLYCHONDRITIS

ALOPECIA AREATA

OPTIC NEURITIS

Interstitial Cystitis

Peyronies Disease

Post prostatectomy Incontinence

Erectile Dysfunction

Int J Urol 2010 Oct17(10)896

Yamamoto T Gotoh M Hattori R Toriyama K Kamei Y Iwaguro H Matsukawa Y Funahashi Y

Periurethral injection of autologous adipose-derived stem cells for the treatment of stress urinary incontinence in patients undergoing radical prostatectomy report of two initial cases

2006

130 (45 men and 85 women with leakage)

Myoblasts (muscle stem cells) used

111 cured 17 more improved

Males 73 improved

Ultrasonography and magnetic resonance imaging showed sustained presence of the injected adipose tissue

Enhanced ultrasonography showed a progressive increase in the blood flow to the injected area

Enhanced ultrasonography showed a progressive increase in the blood flow to the injected area

Japanese protocol

Sphincteric injection of fat and SVF into muscle

Injected through scope under local anesthesia

Parkinsonrsquos

Multiple Sclerosis

Muscular Dystrophy

Neuropathy

Alzheimerrsquos and Mild Cognitive Impairment

Stroke Recovery and Brain Injury

Partial Spinal Cord Injuries

ALS

Retinitis pigmentosa

Age related- dry type- Macular Degeneration

Fortify fat grafts for better survival Face breasts buttocks hands etc

May be able to treat and improve skin quality

May be able to delay aging by adding to existing

fat

SVF alone

SVF with Neograft follicle transfer hair transplantation

Neograft alone

By far the most common type of hair restoration procedure

Involves surgery to the back of the scalp that results in a large scar

The scar will be visible with short hair Significant downtime and pain Typically good results

CRITICAL LIMB ISCHEMIA

WOUND CARE

TMJ SYNDROME

LICHEN SCLEROSIS

ANTI-AGEING

Over 300 cases with one complication

No documented cases of serious injury in human

or animals

International Stem Cell Society (ISCS) ndash reported

over 1000 registered cases Less than 2 complications of any kind

No serious adverse events

Depends on condition being treated

In 2013- we can cryopreserve cells for future use

Active Cancer

Infection

Blood Thinners

Use patients own cells

Provide service during same operative procedure

Minimally manipulate cells

Do not promote therapy or make claims

Performed as a surgical procedure (no laboratory)

Need IRB approved (FDA registered) studies to

support valid claims

International Centers (variably reputable)

Research meetings

Anecdotal and testimonial information

Early results from clinical trials

Veterinary literature

Personal experience with our own patients in USA

(more than 300)

UNIVERSITYPHARMA LABS

FDA APPROVED TRIALS

MOSTLY BONE MARROW AND

SOME EMBRYONIC

LONG TIME FOR OUTCOMES

PATENT ISSUES

FOR INSTITUTIONAL

PROFITGOVT FUNDED

DRUG MODEL

GRASSROOTS COMMUNITY

PHYSICIANrsquoS PRACTICE

BONE MARROW AND ADIPOSE

DERIVED

RAPID CLINICAL EVALUATION

WIDESPREAD AVAILABILITY

NO PATENTS NEEDED

FOR PROFITPATIENT FUNDED

NOT ldquoDRUG ORIENTEDrdquo

CSN In Association with theCalifornia Stem Cell Treatment Center

International research sharing protocols and database including Asia and Canada

High numbers of fresh autologous cells for various degenerative conditions

Standardized Multispecialty care

Advanced deployment methods

Quality Stem Cell Therapy should be available everywhere and easily accessible

WWWSTEMCELLREVOLUTIONCOM

After Three Months

Wanted to share with you the news

I was just released from my eye therapy

I am still waiting on the prism sticker for

my glasses but no more eye patch

After Four Months

I am doing GREAT I have full

vision back and havenrsquot taken my

MS shots since January

After Five Months

This is one Happy Girl

Just left my neurologist and no signs of MS for this Girl

Indiana Stem Cell Treatment CenterDr Robert F Jackson amp Dr Chris Lowery

9660 East 146th Street Suite 100

Noblesville IN 46060

317-773-6677 or 800-708-2462

wwwindianastemcelltreatmentcentercom

Thank you for your Attention

Direct injections into affected arthritic joints

Injection into difficult areas via fluoroscopy

Intravenous injection to affect systemic changes

Injection into spinal fluid or other remote areas

Directly into arteries of body or brain

Directly into soft tissues showing damage

SVF IS REGENERATIVE

SVF IS ANTI-INFLAMMATORY

SVF IS IMMUNO-MODULATORY

Orthopedics

Degenerative Diseases

Cardio-Pulmonary Diseases

Autoimmune Diseases

Urology

Neurology

Cosmetic Surgery

Spinal disk Arthritis and Chronic back or neck pain

Ankle

Hip

Knee

Tendons Ligaments Sports Injuries

Elbow Wrist

Shoulder

Prior to SVF deployment4 months after SVF deployment

End Stage CHF

Ischemic Cardiomyopathy

Acute MI

AsthmaRestrictive Lung Disease

COPDEMPHYSEMA

Not Pulmonary Fibrosis

FIBROMYALGIA

SCLERODERMA

POLYCHONDITIS

CIDP

MYASTHENIA GRAVIS

RHEUMATOID ARTHRITIS

CROHNS DISEASE

AUTO-IMMUNE HEPATITIS

RELAPSING POLYCHONDRITIS

ALOPECIA AREATA

OPTIC NEURITIS

Interstitial Cystitis

Peyronies Disease

Post prostatectomy Incontinence

Erectile Dysfunction

Int J Urol 2010 Oct17(10)896

Yamamoto T Gotoh M Hattori R Toriyama K Kamei Y Iwaguro H Matsukawa Y Funahashi Y

Periurethral injection of autologous adipose-derived stem cells for the treatment of stress urinary incontinence in patients undergoing radical prostatectomy report of two initial cases

2006

130 (45 men and 85 women with leakage)

Myoblasts (muscle stem cells) used

111 cured 17 more improved

Males 73 improved

Ultrasonography and magnetic resonance imaging showed sustained presence of the injected adipose tissue

Enhanced ultrasonography showed a progressive increase in the blood flow to the injected area

Enhanced ultrasonography showed a progressive increase in the blood flow to the injected area

Japanese protocol

Sphincteric injection of fat and SVF into muscle

Injected through scope under local anesthesia

Parkinsonrsquos

Multiple Sclerosis

Muscular Dystrophy

Neuropathy

Alzheimerrsquos and Mild Cognitive Impairment

Stroke Recovery and Brain Injury

Partial Spinal Cord Injuries

ALS

Retinitis pigmentosa

Age related- dry type- Macular Degeneration

Fortify fat grafts for better survival Face breasts buttocks hands etc

May be able to treat and improve skin quality

May be able to delay aging by adding to existing

fat

SVF alone

SVF with Neograft follicle transfer hair transplantation

Neograft alone

By far the most common type of hair restoration procedure

Involves surgery to the back of the scalp that results in a large scar

The scar will be visible with short hair Significant downtime and pain Typically good results

CRITICAL LIMB ISCHEMIA

WOUND CARE

TMJ SYNDROME

LICHEN SCLEROSIS

ANTI-AGEING

Over 300 cases with one complication

No documented cases of serious injury in human

or animals

International Stem Cell Society (ISCS) ndash reported

over 1000 registered cases Less than 2 complications of any kind

No serious adverse events

Depends on condition being treated

In 2013- we can cryopreserve cells for future use

Active Cancer

Infection

Blood Thinners

Use patients own cells

Provide service during same operative procedure

Minimally manipulate cells

Do not promote therapy or make claims

Performed as a surgical procedure (no laboratory)

Need IRB approved (FDA registered) studies to

support valid claims

International Centers (variably reputable)

Research meetings

Anecdotal and testimonial information

Early results from clinical trials

Veterinary literature

Personal experience with our own patients in USA

(more than 300)

UNIVERSITYPHARMA LABS

FDA APPROVED TRIALS

MOSTLY BONE MARROW AND

SOME EMBRYONIC

LONG TIME FOR OUTCOMES

PATENT ISSUES

FOR INSTITUTIONAL

PROFITGOVT FUNDED

DRUG MODEL

GRASSROOTS COMMUNITY

PHYSICIANrsquoS PRACTICE

BONE MARROW AND ADIPOSE

DERIVED

RAPID CLINICAL EVALUATION

WIDESPREAD AVAILABILITY

NO PATENTS NEEDED

FOR PROFITPATIENT FUNDED

NOT ldquoDRUG ORIENTEDrdquo

CSN In Association with theCalifornia Stem Cell Treatment Center

International research sharing protocols and database including Asia and Canada

High numbers of fresh autologous cells for various degenerative conditions

Standardized Multispecialty care

Advanced deployment methods

Quality Stem Cell Therapy should be available everywhere and easily accessible

WWWSTEMCELLREVOLUTIONCOM

After Three Months

Wanted to share with you the news

I was just released from my eye therapy

I am still waiting on the prism sticker for

my glasses but no more eye patch

After Four Months

I am doing GREAT I have full

vision back and havenrsquot taken my

MS shots since January

After Five Months

This is one Happy Girl

Just left my neurologist and no signs of MS for this Girl

Indiana Stem Cell Treatment CenterDr Robert F Jackson amp Dr Chris Lowery

9660 East 146th Street Suite 100

Noblesville IN 46060

317-773-6677 or 800-708-2462

wwwindianastemcelltreatmentcentercom

Thank you for your Attention

SVF IS REGENERATIVE

SVF IS ANTI-INFLAMMATORY

SVF IS IMMUNO-MODULATORY

Orthopedics

Degenerative Diseases

Cardio-Pulmonary Diseases

Autoimmune Diseases

Urology

Neurology

Cosmetic Surgery

Spinal disk Arthritis and Chronic back or neck pain

Ankle

Hip

Knee

Tendons Ligaments Sports Injuries

Elbow Wrist

Shoulder

Prior to SVF deployment4 months after SVF deployment

End Stage CHF

Ischemic Cardiomyopathy

Acute MI

AsthmaRestrictive Lung Disease

COPDEMPHYSEMA

Not Pulmonary Fibrosis

FIBROMYALGIA

SCLERODERMA

POLYCHONDITIS

CIDP

MYASTHENIA GRAVIS

RHEUMATOID ARTHRITIS

CROHNS DISEASE

AUTO-IMMUNE HEPATITIS

RELAPSING POLYCHONDRITIS

ALOPECIA AREATA

OPTIC NEURITIS

Interstitial Cystitis

Peyronies Disease

Post prostatectomy Incontinence

Erectile Dysfunction

Int J Urol 2010 Oct17(10)896

Yamamoto T Gotoh M Hattori R Toriyama K Kamei Y Iwaguro H Matsukawa Y Funahashi Y

Periurethral injection of autologous adipose-derived stem cells for the treatment of stress urinary incontinence in patients undergoing radical prostatectomy report of two initial cases

2006

130 (45 men and 85 women with leakage)

Myoblasts (muscle stem cells) used

111 cured 17 more improved

Males 73 improved

Ultrasonography and magnetic resonance imaging showed sustained presence of the injected adipose tissue

Enhanced ultrasonography showed a progressive increase in the blood flow to the injected area

Enhanced ultrasonography showed a progressive increase in the blood flow to the injected area

Japanese protocol

Sphincteric injection of fat and SVF into muscle

Injected through scope under local anesthesia

Parkinsonrsquos

Multiple Sclerosis

Muscular Dystrophy

Neuropathy

Alzheimerrsquos and Mild Cognitive Impairment

Stroke Recovery and Brain Injury

Partial Spinal Cord Injuries

ALS

Retinitis pigmentosa

Age related- dry type- Macular Degeneration

Fortify fat grafts for better survival Face breasts buttocks hands etc

May be able to treat and improve skin quality

May be able to delay aging by adding to existing

fat

SVF alone

SVF with Neograft follicle transfer hair transplantation

Neograft alone

By far the most common type of hair restoration procedure

Involves surgery to the back of the scalp that results in a large scar

The scar will be visible with short hair Significant downtime and pain Typically good results

CRITICAL LIMB ISCHEMIA

WOUND CARE

TMJ SYNDROME

LICHEN SCLEROSIS

ANTI-AGEING

Over 300 cases with one complication

No documented cases of serious injury in human

or animals

International Stem Cell Society (ISCS) ndash reported

over 1000 registered cases Less than 2 complications of any kind

No serious adverse events

Depends on condition being treated

In 2013- we can cryopreserve cells for future use

Active Cancer

Infection

Blood Thinners

Use patients own cells

Provide service during same operative procedure

Minimally manipulate cells

Do not promote therapy or make claims

Performed as a surgical procedure (no laboratory)

Need IRB approved (FDA registered) studies to

support valid claims

International Centers (variably reputable)

Research meetings

Anecdotal and testimonial information

Early results from clinical trials

Veterinary literature

Personal experience with our own patients in USA

(more than 300)

UNIVERSITYPHARMA LABS

FDA APPROVED TRIALS

MOSTLY BONE MARROW AND

SOME EMBRYONIC

LONG TIME FOR OUTCOMES

PATENT ISSUES

FOR INSTITUTIONAL

PROFITGOVT FUNDED

DRUG MODEL

GRASSROOTS COMMUNITY

PHYSICIANrsquoS PRACTICE

BONE MARROW AND ADIPOSE

DERIVED

RAPID CLINICAL EVALUATION

WIDESPREAD AVAILABILITY

NO PATENTS NEEDED

FOR PROFITPATIENT FUNDED

NOT ldquoDRUG ORIENTEDrdquo

CSN In Association with theCalifornia Stem Cell Treatment Center

International research sharing protocols and database including Asia and Canada

High numbers of fresh autologous cells for various degenerative conditions

Standardized Multispecialty care

Advanced deployment methods

Quality Stem Cell Therapy should be available everywhere and easily accessible

WWWSTEMCELLREVOLUTIONCOM

After Three Months

Wanted to share with you the news

I was just released from my eye therapy

I am still waiting on the prism sticker for

my glasses but no more eye patch

After Four Months

I am doing GREAT I have full

vision back and havenrsquot taken my

MS shots since January

After Five Months

This is one Happy Girl

Just left my neurologist and no signs of MS for this Girl

Indiana Stem Cell Treatment CenterDr Robert F Jackson amp Dr Chris Lowery

9660 East 146th Street Suite 100

Noblesville IN 46060

317-773-6677 or 800-708-2462

wwwindianastemcelltreatmentcentercom

Thank you for your Attention

Orthopedics

Degenerative Diseases

Cardio-Pulmonary Diseases

Autoimmune Diseases

Urology

Neurology

Cosmetic Surgery

Spinal disk Arthritis and Chronic back or neck pain

Ankle

Hip

Knee

Tendons Ligaments Sports Injuries

Elbow Wrist

Shoulder

Prior to SVF deployment4 months after SVF deployment

End Stage CHF

Ischemic Cardiomyopathy

Acute MI

AsthmaRestrictive Lung Disease

COPDEMPHYSEMA

Not Pulmonary Fibrosis

FIBROMYALGIA

SCLERODERMA

POLYCHONDITIS

CIDP

MYASTHENIA GRAVIS

RHEUMATOID ARTHRITIS

CROHNS DISEASE

AUTO-IMMUNE HEPATITIS

RELAPSING POLYCHONDRITIS

ALOPECIA AREATA

OPTIC NEURITIS

Interstitial Cystitis

Peyronies Disease

Post prostatectomy Incontinence

Erectile Dysfunction

Int J Urol 2010 Oct17(10)896

Yamamoto T Gotoh M Hattori R Toriyama K Kamei Y Iwaguro H Matsukawa Y Funahashi Y

Periurethral injection of autologous adipose-derived stem cells for the treatment of stress urinary incontinence in patients undergoing radical prostatectomy report of two initial cases

2006

130 (45 men and 85 women with leakage)

Myoblasts (muscle stem cells) used

111 cured 17 more improved

Males 73 improved

Ultrasonography and magnetic resonance imaging showed sustained presence of the injected adipose tissue

Enhanced ultrasonography showed a progressive increase in the blood flow to the injected area

Enhanced ultrasonography showed a progressive increase in the blood flow to the injected area

Japanese protocol

Sphincteric injection of fat and SVF into muscle

Injected through scope under local anesthesia

Parkinsonrsquos

Multiple Sclerosis

Muscular Dystrophy

Neuropathy

Alzheimerrsquos and Mild Cognitive Impairment

Stroke Recovery and Brain Injury

Partial Spinal Cord Injuries

ALS

Retinitis pigmentosa

Age related- dry type- Macular Degeneration

Fortify fat grafts for better survival Face breasts buttocks hands etc

May be able to treat and improve skin quality

May be able to delay aging by adding to existing

fat

SVF alone

SVF with Neograft follicle transfer hair transplantation

Neograft alone

By far the most common type of hair restoration procedure

Involves surgery to the back of the scalp that results in a large scar

The scar will be visible with short hair Significant downtime and pain Typically good results

CRITICAL LIMB ISCHEMIA

WOUND CARE

TMJ SYNDROME

LICHEN SCLEROSIS

ANTI-AGEING

Over 300 cases with one complication

No documented cases of serious injury in human

or animals

International Stem Cell Society (ISCS) ndash reported

over 1000 registered cases Less than 2 complications of any kind

No serious adverse events

Depends on condition being treated

In 2013- we can cryopreserve cells for future use

Active Cancer

Infection

Blood Thinners

Use patients own cells

Provide service during same operative procedure

Minimally manipulate cells

Do not promote therapy or make claims

Performed as a surgical procedure (no laboratory)

Need IRB approved (FDA registered) studies to

support valid claims

International Centers (variably reputable)

Research meetings

Anecdotal and testimonial information

Early results from clinical trials

Veterinary literature

Personal experience with our own patients in USA

(more than 300)

UNIVERSITYPHARMA LABS

FDA APPROVED TRIALS

MOSTLY BONE MARROW AND

SOME EMBRYONIC

LONG TIME FOR OUTCOMES

PATENT ISSUES

FOR INSTITUTIONAL

PROFITGOVT FUNDED

DRUG MODEL

GRASSROOTS COMMUNITY

PHYSICIANrsquoS PRACTICE

BONE MARROW AND ADIPOSE

DERIVED

RAPID CLINICAL EVALUATION

WIDESPREAD AVAILABILITY

NO PATENTS NEEDED

FOR PROFITPATIENT FUNDED

NOT ldquoDRUG ORIENTEDrdquo

CSN In Association with theCalifornia Stem Cell Treatment Center

International research sharing protocols and database including Asia and Canada

High numbers of fresh autologous cells for various degenerative conditions

Standardized Multispecialty care

Advanced deployment methods

Quality Stem Cell Therapy should be available everywhere and easily accessible

WWWSTEMCELLREVOLUTIONCOM

After Three Months

Wanted to share with you the news

I was just released from my eye therapy

I am still waiting on the prism sticker for

my glasses but no more eye patch

After Four Months

I am doing GREAT I have full

vision back and havenrsquot taken my

MS shots since January

After Five Months

This is one Happy Girl

Just left my neurologist and no signs of MS for this Girl

Indiana Stem Cell Treatment CenterDr Robert F Jackson amp Dr Chris Lowery

9660 East 146th Street Suite 100

Noblesville IN 46060

317-773-6677 or 800-708-2462

wwwindianastemcelltreatmentcentercom

Thank you for your Attention

Spinal disk Arthritis and Chronic back or neck pain

Ankle

Hip

Knee

Tendons Ligaments Sports Injuries

Elbow Wrist

Shoulder

Prior to SVF deployment4 months after SVF deployment

End Stage CHF

Ischemic Cardiomyopathy

Acute MI

AsthmaRestrictive Lung Disease

COPDEMPHYSEMA

Not Pulmonary Fibrosis

FIBROMYALGIA

SCLERODERMA

POLYCHONDITIS

CIDP

MYASTHENIA GRAVIS

RHEUMATOID ARTHRITIS

CROHNS DISEASE

AUTO-IMMUNE HEPATITIS

RELAPSING POLYCHONDRITIS

ALOPECIA AREATA

OPTIC NEURITIS

Interstitial Cystitis

Peyronies Disease

Post prostatectomy Incontinence

Erectile Dysfunction

Int J Urol 2010 Oct17(10)896

Yamamoto T Gotoh M Hattori R Toriyama K Kamei Y Iwaguro H Matsukawa Y Funahashi Y

Periurethral injection of autologous adipose-derived stem cells for the treatment of stress urinary incontinence in patients undergoing radical prostatectomy report of two initial cases

2006

130 (45 men and 85 women with leakage)

Myoblasts (muscle stem cells) used

111 cured 17 more improved

Males 73 improved

Ultrasonography and magnetic resonance imaging showed sustained presence of the injected adipose tissue

Enhanced ultrasonography showed a progressive increase in the blood flow to the injected area

Enhanced ultrasonography showed a progressive increase in the blood flow to the injected area

Japanese protocol

Sphincteric injection of fat and SVF into muscle

Injected through scope under local anesthesia

Parkinsonrsquos

Multiple Sclerosis

Muscular Dystrophy

Neuropathy

Alzheimerrsquos and Mild Cognitive Impairment

Stroke Recovery and Brain Injury

Partial Spinal Cord Injuries

ALS

Retinitis pigmentosa

Age related- dry type- Macular Degeneration

Fortify fat grafts for better survival Face breasts buttocks hands etc

May be able to treat and improve skin quality

May be able to delay aging by adding to existing

fat

SVF alone

SVF with Neograft follicle transfer hair transplantation

Neograft alone

By far the most common type of hair restoration procedure

Involves surgery to the back of the scalp that results in a large scar

The scar will be visible with short hair Significant downtime and pain Typically good results

CRITICAL LIMB ISCHEMIA

WOUND CARE

TMJ SYNDROME

LICHEN SCLEROSIS

ANTI-AGEING

Over 300 cases with one complication

No documented cases of serious injury in human

or animals

International Stem Cell Society (ISCS) ndash reported

over 1000 registered cases Less than 2 complications of any kind

No serious adverse events

Depends on condition being treated

In 2013- we can cryopreserve cells for future use

Active Cancer

Infection

Blood Thinners

Use patients own cells

Provide service during same operative procedure

Minimally manipulate cells

Do not promote therapy or make claims

Performed as a surgical procedure (no laboratory)

Need IRB approved (FDA registered) studies to

support valid claims

International Centers (variably reputable)

Research meetings

Anecdotal and testimonial information

Early results from clinical trials

Veterinary literature

Personal experience with our own patients in USA

(more than 300)

UNIVERSITYPHARMA LABS

FDA APPROVED TRIALS

MOSTLY BONE MARROW AND

SOME EMBRYONIC

LONG TIME FOR OUTCOMES

PATENT ISSUES

FOR INSTITUTIONAL

PROFITGOVT FUNDED

DRUG MODEL

GRASSROOTS COMMUNITY

PHYSICIANrsquoS PRACTICE

BONE MARROW AND ADIPOSE

DERIVED

RAPID CLINICAL EVALUATION

WIDESPREAD AVAILABILITY

NO PATENTS NEEDED

FOR PROFITPATIENT FUNDED

NOT ldquoDRUG ORIENTEDrdquo

CSN In Association with theCalifornia Stem Cell Treatment Center

International research sharing protocols and database including Asia and Canada

High numbers of fresh autologous cells for various degenerative conditions

Standardized Multispecialty care

Advanced deployment methods

Quality Stem Cell Therapy should be available everywhere and easily accessible

WWWSTEMCELLREVOLUTIONCOM

After Three Months

Wanted to share with you the news

I was just released from my eye therapy

I am still waiting on the prism sticker for

my glasses but no more eye patch

After Four Months

I am doing GREAT I have full

vision back and havenrsquot taken my

MS shots since January

After Five Months

This is one Happy Girl

Just left my neurologist and no signs of MS for this Girl

Indiana Stem Cell Treatment CenterDr Robert F Jackson amp Dr Chris Lowery

9660 East 146th Street Suite 100

Noblesville IN 46060

317-773-6677 or 800-708-2462

wwwindianastemcelltreatmentcentercom

Thank you for your Attention

Prior to SVF deployment4 months after SVF deployment

End Stage CHF

Ischemic Cardiomyopathy

Acute MI

AsthmaRestrictive Lung Disease

COPDEMPHYSEMA

Not Pulmonary Fibrosis

FIBROMYALGIA

SCLERODERMA

POLYCHONDITIS

CIDP

MYASTHENIA GRAVIS

RHEUMATOID ARTHRITIS

CROHNS DISEASE

AUTO-IMMUNE HEPATITIS

RELAPSING POLYCHONDRITIS

ALOPECIA AREATA

OPTIC NEURITIS

Interstitial Cystitis

Peyronies Disease

Post prostatectomy Incontinence

Erectile Dysfunction

Int J Urol 2010 Oct17(10)896

Yamamoto T Gotoh M Hattori R Toriyama K Kamei Y Iwaguro H Matsukawa Y Funahashi Y

Periurethral injection of autologous adipose-derived stem cells for the treatment of stress urinary incontinence in patients undergoing radical prostatectomy report of two initial cases

2006

130 (45 men and 85 women with leakage)

Myoblasts (muscle stem cells) used

111 cured 17 more improved

Males 73 improved

Ultrasonography and magnetic resonance imaging showed sustained presence of the injected adipose tissue

Enhanced ultrasonography showed a progressive increase in the blood flow to the injected area

Enhanced ultrasonography showed a progressive increase in the blood flow to the injected area

Japanese protocol

Sphincteric injection of fat and SVF into muscle

Injected through scope under local anesthesia

Parkinsonrsquos

Multiple Sclerosis

Muscular Dystrophy

Neuropathy

Alzheimerrsquos and Mild Cognitive Impairment

Stroke Recovery and Brain Injury

Partial Spinal Cord Injuries

ALS

Retinitis pigmentosa

Age related- dry type- Macular Degeneration

Fortify fat grafts for better survival Face breasts buttocks hands etc

May be able to treat and improve skin quality

May be able to delay aging by adding to existing

fat

SVF alone

SVF with Neograft follicle transfer hair transplantation

Neograft alone

By far the most common type of hair restoration procedure

Involves surgery to the back of the scalp that results in a large scar

The scar will be visible with short hair Significant downtime and pain Typically good results

CRITICAL LIMB ISCHEMIA

WOUND CARE

TMJ SYNDROME

LICHEN SCLEROSIS

ANTI-AGEING

Over 300 cases with one complication

No documented cases of serious injury in human

or animals

International Stem Cell Society (ISCS) ndash reported

over 1000 registered cases Less than 2 complications of any kind

No serious adverse events

Depends on condition being treated

In 2013- we can cryopreserve cells for future use

Active Cancer

Infection

Blood Thinners

Use patients own cells

Provide service during same operative procedure

Minimally manipulate cells

Do not promote therapy or make claims

Performed as a surgical procedure (no laboratory)

Need IRB approved (FDA registered) studies to

support valid claims

International Centers (variably reputable)

Research meetings

Anecdotal and testimonial information

Early results from clinical trials

Veterinary literature

Personal experience with our own patients in USA

(more than 300)

UNIVERSITYPHARMA LABS

FDA APPROVED TRIALS

MOSTLY BONE MARROW AND

SOME EMBRYONIC

LONG TIME FOR OUTCOMES

PATENT ISSUES

FOR INSTITUTIONAL

PROFITGOVT FUNDED

DRUG MODEL

GRASSROOTS COMMUNITY

PHYSICIANrsquoS PRACTICE

BONE MARROW AND ADIPOSE

DERIVED

RAPID CLINICAL EVALUATION

WIDESPREAD AVAILABILITY

NO PATENTS NEEDED

FOR PROFITPATIENT FUNDED

NOT ldquoDRUG ORIENTEDrdquo

CSN In Association with theCalifornia Stem Cell Treatment Center

International research sharing protocols and database including Asia and Canada

High numbers of fresh autologous cells for various degenerative conditions

Standardized Multispecialty care

Advanced deployment methods

Quality Stem Cell Therapy should be available everywhere and easily accessible

WWWSTEMCELLREVOLUTIONCOM

After Three Months

Wanted to share with you the news

I was just released from my eye therapy

I am still waiting on the prism sticker for

my glasses but no more eye patch

After Four Months

I am doing GREAT I have full

vision back and havenrsquot taken my

MS shots since January

After Five Months

This is one Happy Girl

Just left my neurologist and no signs of MS for this Girl

Indiana Stem Cell Treatment CenterDr Robert F Jackson amp Dr Chris Lowery

9660 East 146th Street Suite 100

Noblesville IN 46060

317-773-6677 or 800-708-2462

wwwindianastemcelltreatmentcentercom

Thank you for your Attention

End Stage CHF

Ischemic Cardiomyopathy

Acute MI

AsthmaRestrictive Lung Disease

COPDEMPHYSEMA

Not Pulmonary Fibrosis

FIBROMYALGIA

SCLERODERMA

POLYCHONDITIS

CIDP

MYASTHENIA GRAVIS

RHEUMATOID ARTHRITIS

CROHNS DISEASE

AUTO-IMMUNE HEPATITIS

RELAPSING POLYCHONDRITIS

ALOPECIA AREATA

OPTIC NEURITIS

Interstitial Cystitis

Peyronies Disease

Post prostatectomy Incontinence

Erectile Dysfunction

Int J Urol 2010 Oct17(10)896

Yamamoto T Gotoh M Hattori R Toriyama K Kamei Y Iwaguro H Matsukawa Y Funahashi Y

Periurethral injection of autologous adipose-derived stem cells for the treatment of stress urinary incontinence in patients undergoing radical prostatectomy report of two initial cases

2006

130 (45 men and 85 women with leakage)

Myoblasts (muscle stem cells) used

111 cured 17 more improved

Males 73 improved

Ultrasonography and magnetic resonance imaging showed sustained presence of the injected adipose tissue

Enhanced ultrasonography showed a progressive increase in the blood flow to the injected area

Enhanced ultrasonography showed a progressive increase in the blood flow to the injected area

Japanese protocol

Sphincteric injection of fat and SVF into muscle

Injected through scope under local anesthesia

Parkinsonrsquos

Multiple Sclerosis

Muscular Dystrophy

Neuropathy

Alzheimerrsquos and Mild Cognitive Impairment

Stroke Recovery and Brain Injury

Partial Spinal Cord Injuries

ALS

Retinitis pigmentosa

Age related- dry type- Macular Degeneration

Fortify fat grafts for better survival Face breasts buttocks hands etc

May be able to treat and improve skin quality

May be able to delay aging by adding to existing

fat

SVF alone

SVF with Neograft follicle transfer hair transplantation

Neograft alone

By far the most common type of hair restoration procedure

Involves surgery to the back of the scalp that results in a large scar

The scar will be visible with short hair Significant downtime and pain Typically good results

CRITICAL LIMB ISCHEMIA

WOUND CARE

TMJ SYNDROME

LICHEN SCLEROSIS

ANTI-AGEING

Over 300 cases with one complication

No documented cases of serious injury in human

or animals

International Stem Cell Society (ISCS) ndash reported

over 1000 registered cases Less than 2 complications of any kind

No serious adverse events

Depends on condition being treated

In 2013- we can cryopreserve cells for future use

Active Cancer

Infection

Blood Thinners

Use patients own cells

Provide service during same operative procedure

Minimally manipulate cells

Do not promote therapy or make claims

Performed as a surgical procedure (no laboratory)

Need IRB approved (FDA registered) studies to

support valid claims

International Centers (variably reputable)

Research meetings

Anecdotal and testimonial information

Early results from clinical trials

Veterinary literature

Personal experience with our own patients in USA

(more than 300)

UNIVERSITYPHARMA LABS

FDA APPROVED TRIALS

MOSTLY BONE MARROW AND

SOME EMBRYONIC

LONG TIME FOR OUTCOMES

PATENT ISSUES

FOR INSTITUTIONAL

PROFITGOVT FUNDED

DRUG MODEL

GRASSROOTS COMMUNITY

PHYSICIANrsquoS PRACTICE

BONE MARROW AND ADIPOSE

DERIVED

RAPID CLINICAL EVALUATION

WIDESPREAD AVAILABILITY

NO PATENTS NEEDED

FOR PROFITPATIENT FUNDED

NOT ldquoDRUG ORIENTEDrdquo

CSN In Association with theCalifornia Stem Cell Treatment Center

International research sharing protocols and database including Asia and Canada

High numbers of fresh autologous cells for various degenerative conditions

Standardized Multispecialty care

Advanced deployment methods

Quality Stem Cell Therapy should be available everywhere and easily accessible

WWWSTEMCELLREVOLUTIONCOM

After Three Months

Wanted to share with you the news

I was just released from my eye therapy

I am still waiting on the prism sticker for

my glasses but no more eye patch

After Four Months

I am doing GREAT I have full

vision back and havenrsquot taken my

MS shots since January

After Five Months

This is one Happy Girl

Just left my neurologist and no signs of MS for this Girl

Indiana Stem Cell Treatment CenterDr Robert F Jackson amp Dr Chris Lowery

9660 East 146th Street Suite 100

Noblesville IN 46060

317-773-6677 or 800-708-2462

wwwindianastemcelltreatmentcentercom

Thank you for your Attention

FIBROMYALGIA

SCLERODERMA

POLYCHONDITIS

CIDP

MYASTHENIA GRAVIS

RHEUMATOID ARTHRITIS

CROHNS DISEASE

AUTO-IMMUNE HEPATITIS

RELAPSING POLYCHONDRITIS

ALOPECIA AREATA

OPTIC NEURITIS

Interstitial Cystitis

Peyronies Disease

Post prostatectomy Incontinence

Erectile Dysfunction

Int J Urol 2010 Oct17(10)896

Yamamoto T Gotoh M Hattori R Toriyama K Kamei Y Iwaguro H Matsukawa Y Funahashi Y

Periurethral injection of autologous adipose-derived stem cells for the treatment of stress urinary incontinence in patients undergoing radical prostatectomy report of two initial cases

2006

130 (45 men and 85 women with leakage)

Myoblasts (muscle stem cells) used

111 cured 17 more improved

Males 73 improved

Ultrasonography and magnetic resonance imaging showed sustained presence of the injected adipose tissue

Enhanced ultrasonography showed a progressive increase in the blood flow to the injected area

Enhanced ultrasonography showed a progressive increase in the blood flow to the injected area

Japanese protocol

Sphincteric injection of fat and SVF into muscle

Injected through scope under local anesthesia

Parkinsonrsquos

Multiple Sclerosis

Muscular Dystrophy

Neuropathy

Alzheimerrsquos and Mild Cognitive Impairment

Stroke Recovery and Brain Injury

Partial Spinal Cord Injuries

ALS

Retinitis pigmentosa

Age related- dry type- Macular Degeneration

Fortify fat grafts for better survival Face breasts buttocks hands etc

May be able to treat and improve skin quality

May be able to delay aging by adding to existing

fat

SVF alone

SVF with Neograft follicle transfer hair transplantation

Neograft alone

By far the most common type of hair restoration procedure

Involves surgery to the back of the scalp that results in a large scar

The scar will be visible with short hair Significant downtime and pain Typically good results

CRITICAL LIMB ISCHEMIA

WOUND CARE

TMJ SYNDROME

LICHEN SCLEROSIS

ANTI-AGEING

Over 300 cases with one complication

No documented cases of serious injury in human

or animals

International Stem Cell Society (ISCS) ndash reported

over 1000 registered cases Less than 2 complications of any kind

No serious adverse events

Depends on condition being treated

In 2013- we can cryopreserve cells for future use

Active Cancer

Infection

Blood Thinners

Use patients own cells

Provide service during same operative procedure

Minimally manipulate cells

Do not promote therapy or make claims

Performed as a surgical procedure (no laboratory)

Need IRB approved (FDA registered) studies to

support valid claims

International Centers (variably reputable)

Research meetings

Anecdotal and testimonial information

Early results from clinical trials

Veterinary literature

Personal experience with our own patients in USA

(more than 300)

UNIVERSITYPHARMA LABS

FDA APPROVED TRIALS

MOSTLY BONE MARROW AND

SOME EMBRYONIC

LONG TIME FOR OUTCOMES

PATENT ISSUES

FOR INSTITUTIONAL

PROFITGOVT FUNDED

DRUG MODEL

GRASSROOTS COMMUNITY

PHYSICIANrsquoS PRACTICE

BONE MARROW AND ADIPOSE

DERIVED

RAPID CLINICAL EVALUATION

WIDESPREAD AVAILABILITY

NO PATENTS NEEDED

FOR PROFITPATIENT FUNDED

NOT ldquoDRUG ORIENTEDrdquo

CSN In Association with theCalifornia Stem Cell Treatment Center

International research sharing protocols and database including Asia and Canada

High numbers of fresh autologous cells for various degenerative conditions

Standardized Multispecialty care

Advanced deployment methods

Quality Stem Cell Therapy should be available everywhere and easily accessible

WWWSTEMCELLREVOLUTIONCOM

After Three Months

Wanted to share with you the news

I was just released from my eye therapy

I am still waiting on the prism sticker for

my glasses but no more eye patch

After Four Months

I am doing GREAT I have full

vision back and havenrsquot taken my

MS shots since January

After Five Months

This is one Happy Girl

Just left my neurologist and no signs of MS for this Girl

Indiana Stem Cell Treatment CenterDr Robert F Jackson amp Dr Chris Lowery

9660 East 146th Street Suite 100

Noblesville IN 46060

317-773-6677 or 800-708-2462

wwwindianastemcelltreatmentcentercom

Thank you for your Attention

Interstitial Cystitis

Peyronies Disease

Post prostatectomy Incontinence

Erectile Dysfunction

Int J Urol 2010 Oct17(10)896

Yamamoto T Gotoh M Hattori R Toriyama K Kamei Y Iwaguro H Matsukawa Y Funahashi Y

Periurethral injection of autologous adipose-derived stem cells for the treatment of stress urinary incontinence in patients undergoing radical prostatectomy report of two initial cases

2006

130 (45 men and 85 women with leakage)

Myoblasts (muscle stem cells) used

111 cured 17 more improved

Males 73 improved

Ultrasonography and magnetic resonance imaging showed sustained presence of the injected adipose tissue

Enhanced ultrasonography showed a progressive increase in the blood flow to the injected area

Enhanced ultrasonography showed a progressive increase in the blood flow to the injected area

Japanese protocol

Sphincteric injection of fat and SVF into muscle

Injected through scope under local anesthesia

Parkinsonrsquos

Multiple Sclerosis

Muscular Dystrophy

Neuropathy

Alzheimerrsquos and Mild Cognitive Impairment

Stroke Recovery and Brain Injury

Partial Spinal Cord Injuries

ALS

Retinitis pigmentosa

Age related- dry type- Macular Degeneration

Fortify fat grafts for better survival Face breasts buttocks hands etc

May be able to treat and improve skin quality

May be able to delay aging by adding to existing

fat

SVF alone

SVF with Neograft follicle transfer hair transplantation

Neograft alone

By far the most common type of hair restoration procedure

Involves surgery to the back of the scalp that results in a large scar

The scar will be visible with short hair Significant downtime and pain Typically good results

CRITICAL LIMB ISCHEMIA

WOUND CARE

TMJ SYNDROME

LICHEN SCLEROSIS

ANTI-AGEING

Over 300 cases with one complication

No documented cases of serious injury in human

or animals

International Stem Cell Society (ISCS) ndash reported

over 1000 registered cases Less than 2 complications of any kind

No serious adverse events

Depends on condition being treated

In 2013- we can cryopreserve cells for future use

Active Cancer

Infection

Blood Thinners

Use patients own cells

Provide service during same operative procedure

Minimally manipulate cells

Do not promote therapy or make claims

Performed as a surgical procedure (no laboratory)

Need IRB approved (FDA registered) studies to

support valid claims

International Centers (variably reputable)

Research meetings

Anecdotal and testimonial information

Early results from clinical trials

Veterinary literature

Personal experience with our own patients in USA

(more than 300)

UNIVERSITYPHARMA LABS

FDA APPROVED TRIALS

MOSTLY BONE MARROW AND

SOME EMBRYONIC

LONG TIME FOR OUTCOMES

PATENT ISSUES

FOR INSTITUTIONAL

PROFITGOVT FUNDED

DRUG MODEL

GRASSROOTS COMMUNITY

PHYSICIANrsquoS PRACTICE

BONE MARROW AND ADIPOSE

DERIVED

RAPID CLINICAL EVALUATION

WIDESPREAD AVAILABILITY

NO PATENTS NEEDED

FOR PROFITPATIENT FUNDED

NOT ldquoDRUG ORIENTEDrdquo

CSN In Association with theCalifornia Stem Cell Treatment Center

International research sharing protocols and database including Asia and Canada

High numbers of fresh autologous cells for various degenerative conditions

Standardized Multispecialty care

Advanced deployment methods

Quality Stem Cell Therapy should be available everywhere and easily accessible

WWWSTEMCELLREVOLUTIONCOM

After Three Months

Wanted to share with you the news

I was just released from my eye therapy

I am still waiting on the prism sticker for

my glasses but no more eye patch

After Four Months

I am doing GREAT I have full

vision back and havenrsquot taken my

MS shots since January

After Five Months

This is one Happy Girl

Just left my neurologist and no signs of MS for this Girl

Indiana Stem Cell Treatment CenterDr Robert F Jackson amp Dr Chris Lowery

9660 East 146th Street Suite 100

Noblesville IN 46060

317-773-6677 or 800-708-2462

wwwindianastemcelltreatmentcentercom

Thank you for your Attention

Int J Urol 2010 Oct17(10)896

Yamamoto T Gotoh M Hattori R Toriyama K Kamei Y Iwaguro H Matsukawa Y Funahashi Y

Periurethral injection of autologous adipose-derived stem cells for the treatment of stress urinary incontinence in patients undergoing radical prostatectomy report of two initial cases

2006

130 (45 men and 85 women with leakage)

Myoblasts (muscle stem cells) used

111 cured 17 more improved

Males 73 improved

Ultrasonography and magnetic resonance imaging showed sustained presence of the injected adipose tissue

Enhanced ultrasonography showed a progressive increase in the blood flow to the injected area

Enhanced ultrasonography showed a progressive increase in the blood flow to the injected area

Japanese protocol

Sphincteric injection of fat and SVF into muscle

Injected through scope under local anesthesia

Parkinsonrsquos

Multiple Sclerosis

Muscular Dystrophy

Neuropathy

Alzheimerrsquos and Mild Cognitive Impairment

Stroke Recovery and Brain Injury

Partial Spinal Cord Injuries

ALS

Retinitis pigmentosa

Age related- dry type- Macular Degeneration

Fortify fat grafts for better survival Face breasts buttocks hands etc

May be able to treat and improve skin quality

May be able to delay aging by adding to existing

fat

SVF alone

SVF with Neograft follicle transfer hair transplantation

Neograft alone

By far the most common type of hair restoration procedure

Involves surgery to the back of the scalp that results in a large scar

The scar will be visible with short hair Significant downtime and pain Typically good results

CRITICAL LIMB ISCHEMIA

WOUND CARE

TMJ SYNDROME

LICHEN SCLEROSIS

ANTI-AGEING

Over 300 cases with one complication

No documented cases of serious injury in human

or animals

International Stem Cell Society (ISCS) ndash reported

over 1000 registered cases Less than 2 complications of any kind

No serious adverse events

Depends on condition being treated

In 2013- we can cryopreserve cells for future use

Active Cancer

Infection

Blood Thinners

Use patients own cells

Provide service during same operative procedure

Minimally manipulate cells

Do not promote therapy or make claims

Performed as a surgical procedure (no laboratory)

Need IRB approved (FDA registered) studies to

support valid claims

International Centers (variably reputable)

Research meetings

Anecdotal and testimonial information

Early results from clinical trials

Veterinary literature

Personal experience with our own patients in USA

(more than 300)

UNIVERSITYPHARMA LABS

FDA APPROVED TRIALS

MOSTLY BONE MARROW AND

SOME EMBRYONIC

LONG TIME FOR OUTCOMES

PATENT ISSUES

FOR INSTITUTIONAL

PROFITGOVT FUNDED

DRUG MODEL

GRASSROOTS COMMUNITY

PHYSICIANrsquoS PRACTICE

BONE MARROW AND ADIPOSE

DERIVED

RAPID CLINICAL EVALUATION

WIDESPREAD AVAILABILITY

NO PATENTS NEEDED

FOR PROFITPATIENT FUNDED

NOT ldquoDRUG ORIENTEDrdquo

CSN In Association with theCalifornia Stem Cell Treatment Center

International research sharing protocols and database including Asia and Canada

High numbers of fresh autologous cells for various degenerative conditions

Standardized Multispecialty care

Advanced deployment methods

Quality Stem Cell Therapy should be available everywhere and easily accessible

WWWSTEMCELLREVOLUTIONCOM

After Three Months

Wanted to share with you the news

I was just released from my eye therapy

I am still waiting on the prism sticker for

my glasses but no more eye patch

After Four Months

I am doing GREAT I have full

vision back and havenrsquot taken my

MS shots since January

After Five Months

This is one Happy Girl

Just left my neurologist and no signs of MS for this Girl

Indiana Stem Cell Treatment CenterDr Robert F Jackson amp Dr Chris Lowery

9660 East 146th Street Suite 100

Noblesville IN 46060

317-773-6677 or 800-708-2462

wwwindianastemcelltreatmentcentercom

Thank you for your Attention

2006

130 (45 men and 85 women with leakage)

Myoblasts (muscle stem cells) used

111 cured 17 more improved

Males 73 improved

Ultrasonography and magnetic resonance imaging showed sustained presence of the injected adipose tissue

Enhanced ultrasonography showed a progressive increase in the blood flow to the injected area

Enhanced ultrasonography showed a progressive increase in the blood flow to the injected area

Japanese protocol

Sphincteric injection of fat and SVF into muscle

Injected through scope under local anesthesia

Parkinsonrsquos

Multiple Sclerosis

Muscular Dystrophy

Neuropathy

Alzheimerrsquos and Mild Cognitive Impairment

Stroke Recovery and Brain Injury

Partial Spinal Cord Injuries

ALS

Retinitis pigmentosa

Age related- dry type- Macular Degeneration

Fortify fat grafts for better survival Face breasts buttocks hands etc

May be able to treat and improve skin quality

May be able to delay aging by adding to existing

fat

SVF alone

SVF with Neograft follicle transfer hair transplantation

Neograft alone

By far the most common type of hair restoration procedure

Involves surgery to the back of the scalp that results in a large scar

The scar will be visible with short hair Significant downtime and pain Typically good results

CRITICAL LIMB ISCHEMIA

WOUND CARE

TMJ SYNDROME

LICHEN SCLEROSIS

ANTI-AGEING

Over 300 cases with one complication

No documented cases of serious injury in human

or animals

International Stem Cell Society (ISCS) ndash reported

over 1000 registered cases Less than 2 complications of any kind

No serious adverse events

Depends on condition being treated

In 2013- we can cryopreserve cells for future use

Active Cancer

Infection

Blood Thinners

Use patients own cells

Provide service during same operative procedure

Minimally manipulate cells

Do not promote therapy or make claims

Performed as a surgical procedure (no laboratory)

Need IRB approved (FDA registered) studies to

support valid claims

International Centers (variably reputable)

Research meetings

Anecdotal and testimonial information

Early results from clinical trials

Veterinary literature

Personal experience with our own patients in USA

(more than 300)

UNIVERSITYPHARMA LABS

FDA APPROVED TRIALS

MOSTLY BONE MARROW AND

SOME EMBRYONIC

LONG TIME FOR OUTCOMES

PATENT ISSUES

FOR INSTITUTIONAL

PROFITGOVT FUNDED

DRUG MODEL

GRASSROOTS COMMUNITY

PHYSICIANrsquoS PRACTICE

BONE MARROW AND ADIPOSE

DERIVED

RAPID CLINICAL EVALUATION

WIDESPREAD AVAILABILITY

NO PATENTS NEEDED

FOR PROFITPATIENT FUNDED

NOT ldquoDRUG ORIENTEDrdquo

CSN In Association with theCalifornia Stem Cell Treatment Center

International research sharing protocols and database including Asia and Canada

High numbers of fresh autologous cells for various degenerative conditions

Standardized Multispecialty care

Advanced deployment methods

Quality Stem Cell Therapy should be available everywhere and easily accessible

WWWSTEMCELLREVOLUTIONCOM

After Three Months

Wanted to share with you the news

I was just released from my eye therapy

I am still waiting on the prism sticker for

my glasses but no more eye patch

After Four Months

I am doing GREAT I have full

vision back and havenrsquot taken my

MS shots since January

After Five Months

This is one Happy Girl

Just left my neurologist and no signs of MS for this Girl

Indiana Stem Cell Treatment CenterDr Robert F Jackson amp Dr Chris Lowery

9660 East 146th Street Suite 100

Noblesville IN 46060

317-773-6677 or 800-708-2462

wwwindianastemcelltreatmentcentercom

Thank you for your Attention

Ultrasonography and magnetic resonance imaging showed sustained presence of the injected adipose tissue

Enhanced ultrasonography showed a progressive increase in the blood flow to the injected area

Enhanced ultrasonography showed a progressive increase in the blood flow to the injected area

Japanese protocol

Sphincteric injection of fat and SVF into muscle

Injected through scope under local anesthesia

Parkinsonrsquos

Multiple Sclerosis

Muscular Dystrophy

Neuropathy

Alzheimerrsquos and Mild Cognitive Impairment

Stroke Recovery and Brain Injury

Partial Spinal Cord Injuries

ALS

Retinitis pigmentosa

Age related- dry type- Macular Degeneration

Fortify fat grafts for better survival Face breasts buttocks hands etc

May be able to treat and improve skin quality

May be able to delay aging by adding to existing

fat

SVF alone

SVF with Neograft follicle transfer hair transplantation

Neograft alone

By far the most common type of hair restoration procedure

Involves surgery to the back of the scalp that results in a large scar

The scar will be visible with short hair Significant downtime and pain Typically good results

CRITICAL LIMB ISCHEMIA

WOUND CARE

TMJ SYNDROME

LICHEN SCLEROSIS

ANTI-AGEING

Over 300 cases with one complication

No documented cases of serious injury in human

or animals

International Stem Cell Society (ISCS) ndash reported

over 1000 registered cases Less than 2 complications of any kind

No serious adverse events

Depends on condition being treated

In 2013- we can cryopreserve cells for future use

Active Cancer

Infection

Blood Thinners

Use patients own cells

Provide service during same operative procedure

Minimally manipulate cells

Do not promote therapy or make claims

Performed as a surgical procedure (no laboratory)

Need IRB approved (FDA registered) studies to

support valid claims

International Centers (variably reputable)

Research meetings

Anecdotal and testimonial information

Early results from clinical trials

Veterinary literature

Personal experience with our own patients in USA

(more than 300)

UNIVERSITYPHARMA LABS

FDA APPROVED TRIALS

MOSTLY BONE MARROW AND

SOME EMBRYONIC

LONG TIME FOR OUTCOMES

PATENT ISSUES

FOR INSTITUTIONAL

PROFITGOVT FUNDED

DRUG MODEL

GRASSROOTS COMMUNITY

PHYSICIANrsquoS PRACTICE

BONE MARROW AND ADIPOSE

DERIVED

RAPID CLINICAL EVALUATION

WIDESPREAD AVAILABILITY

NO PATENTS NEEDED

FOR PROFITPATIENT FUNDED

NOT ldquoDRUG ORIENTEDrdquo

CSN In Association with theCalifornia Stem Cell Treatment Center

International research sharing protocols and database including Asia and Canada

High numbers of fresh autologous cells for various degenerative conditions

Standardized Multispecialty care

Advanced deployment methods

Quality Stem Cell Therapy should be available everywhere and easily accessible

WWWSTEMCELLREVOLUTIONCOM

After Three Months

Wanted to share with you the news

I was just released from my eye therapy

I am still waiting on the prism sticker for

my glasses but no more eye patch

After Four Months

I am doing GREAT I have full

vision back and havenrsquot taken my

MS shots since January

After Five Months

This is one Happy Girl

Just left my neurologist and no signs of MS for this Girl

Indiana Stem Cell Treatment CenterDr Robert F Jackson amp Dr Chris Lowery

9660 East 146th Street Suite 100

Noblesville IN 46060

317-773-6677 or 800-708-2462

wwwindianastemcelltreatmentcentercom

Thank you for your Attention

Japanese protocol

Sphincteric injection of fat and SVF into muscle

Injected through scope under local anesthesia

Parkinsonrsquos

Multiple Sclerosis

Muscular Dystrophy

Neuropathy

Alzheimerrsquos and Mild Cognitive Impairment

Stroke Recovery and Brain Injury

Partial Spinal Cord Injuries

ALS

Retinitis pigmentosa

Age related- dry type- Macular Degeneration

Fortify fat grafts for better survival Face breasts buttocks hands etc

May be able to treat and improve skin quality

May be able to delay aging by adding to existing

fat

SVF alone

SVF with Neograft follicle transfer hair transplantation

Neograft alone

By far the most common type of hair restoration procedure

Involves surgery to the back of the scalp that results in a large scar

The scar will be visible with short hair Significant downtime and pain Typically good results

CRITICAL LIMB ISCHEMIA

WOUND CARE

TMJ SYNDROME

LICHEN SCLEROSIS

ANTI-AGEING

Over 300 cases with one complication

No documented cases of serious injury in human

or animals

International Stem Cell Society (ISCS) ndash reported

over 1000 registered cases Less than 2 complications of any kind

No serious adverse events

Depends on condition being treated

In 2013- we can cryopreserve cells for future use

Active Cancer

Infection

Blood Thinners

Use patients own cells

Provide service during same operative procedure

Minimally manipulate cells

Do not promote therapy or make claims

Performed as a surgical procedure (no laboratory)

Need IRB approved (FDA registered) studies to

support valid claims

International Centers (variably reputable)

Research meetings

Anecdotal and testimonial information

Early results from clinical trials

Veterinary literature

Personal experience with our own patients in USA

(more than 300)

UNIVERSITYPHARMA LABS

FDA APPROVED TRIALS

MOSTLY BONE MARROW AND

SOME EMBRYONIC

LONG TIME FOR OUTCOMES

PATENT ISSUES

FOR INSTITUTIONAL

PROFITGOVT FUNDED

DRUG MODEL

GRASSROOTS COMMUNITY

PHYSICIANrsquoS PRACTICE

BONE MARROW AND ADIPOSE

DERIVED

RAPID CLINICAL EVALUATION

WIDESPREAD AVAILABILITY

NO PATENTS NEEDED

FOR PROFITPATIENT FUNDED

NOT ldquoDRUG ORIENTEDrdquo

CSN In Association with theCalifornia Stem Cell Treatment Center

International research sharing protocols and database including Asia and Canada

High numbers of fresh autologous cells for various degenerative conditions

Standardized Multispecialty care

Advanced deployment methods

Quality Stem Cell Therapy should be available everywhere and easily accessible

WWWSTEMCELLREVOLUTIONCOM

After Three Months

Wanted to share with you the news

I was just released from my eye therapy

I am still waiting on the prism sticker for

my glasses but no more eye patch

After Four Months

I am doing GREAT I have full

vision back and havenrsquot taken my

MS shots since January

After Five Months

This is one Happy Girl

Just left my neurologist and no signs of MS for this Girl

Indiana Stem Cell Treatment CenterDr Robert F Jackson amp Dr Chris Lowery

9660 East 146th Street Suite 100

Noblesville IN 46060

317-773-6677 or 800-708-2462

wwwindianastemcelltreatmentcentercom

Thank you for your Attention

Parkinsonrsquos

Multiple Sclerosis

Muscular Dystrophy

Neuropathy

Alzheimerrsquos and Mild Cognitive Impairment

Stroke Recovery and Brain Injury

Partial Spinal Cord Injuries

ALS

Retinitis pigmentosa

Age related- dry type- Macular Degeneration

Fortify fat grafts for better survival Face breasts buttocks hands etc

May be able to treat and improve skin quality

May be able to delay aging by adding to existing

fat

SVF alone

SVF with Neograft follicle transfer hair transplantation

Neograft alone

By far the most common type of hair restoration procedure

Involves surgery to the back of the scalp that results in a large scar

The scar will be visible with short hair Significant downtime and pain Typically good results

CRITICAL LIMB ISCHEMIA

WOUND CARE

TMJ SYNDROME

LICHEN SCLEROSIS

ANTI-AGEING

Over 300 cases with one complication

No documented cases of serious injury in human

or animals

International Stem Cell Society (ISCS) ndash reported

over 1000 registered cases Less than 2 complications of any kind

No serious adverse events

Depends on condition being treated

In 2013- we can cryopreserve cells for future use

Active Cancer

Infection

Blood Thinners

Use patients own cells

Provide service during same operative procedure

Minimally manipulate cells

Do not promote therapy or make claims

Performed as a surgical procedure (no laboratory)

Need IRB approved (FDA registered) studies to

support valid claims

International Centers (variably reputable)

Research meetings

Anecdotal and testimonial information

Early results from clinical trials

Veterinary literature

Personal experience with our own patients in USA

(more than 300)

UNIVERSITYPHARMA LABS

FDA APPROVED TRIALS

MOSTLY BONE MARROW AND

SOME EMBRYONIC

LONG TIME FOR OUTCOMES

PATENT ISSUES

FOR INSTITUTIONAL

PROFITGOVT FUNDED

DRUG MODEL

GRASSROOTS COMMUNITY

PHYSICIANrsquoS PRACTICE

BONE MARROW AND ADIPOSE

DERIVED

RAPID CLINICAL EVALUATION

WIDESPREAD AVAILABILITY

NO PATENTS NEEDED

FOR PROFITPATIENT FUNDED

NOT ldquoDRUG ORIENTEDrdquo

CSN In Association with theCalifornia Stem Cell Treatment Center

International research sharing protocols and database including Asia and Canada

High numbers of fresh autologous cells for various degenerative conditions

Standardized Multispecialty care

Advanced deployment methods

Quality Stem Cell Therapy should be available everywhere and easily accessible

WWWSTEMCELLREVOLUTIONCOM

After Three Months

Wanted to share with you the news

I was just released from my eye therapy

I am still waiting on the prism sticker for

my glasses but no more eye patch

After Four Months

I am doing GREAT I have full

vision back and havenrsquot taken my

MS shots since January

After Five Months

This is one Happy Girl

Just left my neurologist and no signs of MS for this Girl

Indiana Stem Cell Treatment CenterDr Robert F Jackson amp Dr Chris Lowery

9660 East 146th Street Suite 100

Noblesville IN 46060

317-773-6677 or 800-708-2462

wwwindianastemcelltreatmentcentercom

Thank you for your Attention

Retinitis pigmentosa

Age related- dry type- Macular Degeneration

Fortify fat grafts for better survival Face breasts buttocks hands etc

May be able to treat and improve skin quality

May be able to delay aging by adding to existing

fat

SVF alone

SVF with Neograft follicle transfer hair transplantation

Neograft alone

By far the most common type of hair restoration procedure

Involves surgery to the back of the scalp that results in a large scar

The scar will be visible with short hair Significant downtime and pain Typically good results

CRITICAL LIMB ISCHEMIA

WOUND CARE

TMJ SYNDROME

LICHEN SCLEROSIS

ANTI-AGEING

Over 300 cases with one complication

No documented cases of serious injury in human

or animals

International Stem Cell Society (ISCS) ndash reported

over 1000 registered cases Less than 2 complications of any kind

No serious adverse events

Depends on condition being treated

In 2013- we can cryopreserve cells for future use

Active Cancer

Infection

Blood Thinners

Use patients own cells

Provide service during same operative procedure

Minimally manipulate cells

Do not promote therapy or make claims

Performed as a surgical procedure (no laboratory)

Need IRB approved (FDA registered) studies to

support valid claims

International Centers (variably reputable)

Research meetings

Anecdotal and testimonial information

Early results from clinical trials

Veterinary literature

Personal experience with our own patients in USA

(more than 300)

UNIVERSITYPHARMA LABS

FDA APPROVED TRIALS

MOSTLY BONE MARROW AND

SOME EMBRYONIC

LONG TIME FOR OUTCOMES

PATENT ISSUES

FOR INSTITUTIONAL

PROFITGOVT FUNDED

DRUG MODEL

GRASSROOTS COMMUNITY

PHYSICIANrsquoS PRACTICE

BONE MARROW AND ADIPOSE

DERIVED

RAPID CLINICAL EVALUATION

WIDESPREAD AVAILABILITY

NO PATENTS NEEDED

FOR PROFITPATIENT FUNDED

NOT ldquoDRUG ORIENTEDrdquo

CSN In Association with theCalifornia Stem Cell Treatment Center

International research sharing protocols and database including Asia and Canada

High numbers of fresh autologous cells for various degenerative conditions

Standardized Multispecialty care

Advanced deployment methods

Quality Stem Cell Therapy should be available everywhere and easily accessible

WWWSTEMCELLREVOLUTIONCOM

After Three Months

Wanted to share with you the news

I was just released from my eye therapy

I am still waiting on the prism sticker for

my glasses but no more eye patch

After Four Months

I am doing GREAT I have full

vision back and havenrsquot taken my

MS shots since January

After Five Months

This is one Happy Girl

Just left my neurologist and no signs of MS for this Girl

Indiana Stem Cell Treatment CenterDr Robert F Jackson amp Dr Chris Lowery

9660 East 146th Street Suite 100

Noblesville IN 46060

317-773-6677 or 800-708-2462

wwwindianastemcelltreatmentcentercom

Thank you for your Attention

Fortify fat grafts for better survival Face breasts buttocks hands etc

May be able to treat and improve skin quality

May be able to delay aging by adding to existing

fat

SVF alone

SVF with Neograft follicle transfer hair transplantation

Neograft alone

By far the most common type of hair restoration procedure

Involves surgery to the back of the scalp that results in a large scar

The scar will be visible with short hair Significant downtime and pain Typically good results

CRITICAL LIMB ISCHEMIA

WOUND CARE

TMJ SYNDROME

LICHEN SCLEROSIS

ANTI-AGEING

Over 300 cases with one complication

No documented cases of serious injury in human

or animals

International Stem Cell Society (ISCS) ndash reported

over 1000 registered cases Less than 2 complications of any kind

No serious adverse events

Depends on condition being treated

In 2013- we can cryopreserve cells for future use

Active Cancer

Infection

Blood Thinners

Use patients own cells

Provide service during same operative procedure

Minimally manipulate cells

Do not promote therapy or make claims

Performed as a surgical procedure (no laboratory)

Need IRB approved (FDA registered) studies to

support valid claims

International Centers (variably reputable)

Research meetings

Anecdotal and testimonial information

Early results from clinical trials

Veterinary literature

Personal experience with our own patients in USA

(more than 300)

UNIVERSITYPHARMA LABS

FDA APPROVED TRIALS

MOSTLY BONE MARROW AND

SOME EMBRYONIC

LONG TIME FOR OUTCOMES

PATENT ISSUES

FOR INSTITUTIONAL

PROFITGOVT FUNDED

DRUG MODEL

GRASSROOTS COMMUNITY

PHYSICIANrsquoS PRACTICE

BONE MARROW AND ADIPOSE

DERIVED

RAPID CLINICAL EVALUATION

WIDESPREAD AVAILABILITY

NO PATENTS NEEDED

FOR PROFITPATIENT FUNDED

NOT ldquoDRUG ORIENTEDrdquo

CSN In Association with theCalifornia Stem Cell Treatment Center

International research sharing protocols and database including Asia and Canada

High numbers of fresh autologous cells for various degenerative conditions

Standardized Multispecialty care

Advanced deployment methods

Quality Stem Cell Therapy should be available everywhere and easily accessible

WWWSTEMCELLREVOLUTIONCOM

After Three Months

Wanted to share with you the news

I was just released from my eye therapy

I am still waiting on the prism sticker for

my glasses but no more eye patch

After Four Months

I am doing GREAT I have full

vision back and havenrsquot taken my

MS shots since January

After Five Months

This is one Happy Girl

Just left my neurologist and no signs of MS for this Girl

Indiana Stem Cell Treatment CenterDr Robert F Jackson amp Dr Chris Lowery

9660 East 146th Street Suite 100

Noblesville IN 46060

317-773-6677 or 800-708-2462

wwwindianastemcelltreatmentcentercom

Thank you for your Attention

SVF alone

SVF with Neograft follicle transfer hair transplantation

Neograft alone

By far the most common type of hair restoration procedure

Involves surgery to the back of the scalp that results in a large scar

The scar will be visible with short hair Significant downtime and pain Typically good results

CRITICAL LIMB ISCHEMIA

WOUND CARE

TMJ SYNDROME

LICHEN SCLEROSIS

ANTI-AGEING

Over 300 cases with one complication

No documented cases of serious injury in human

or animals

International Stem Cell Society (ISCS) ndash reported

over 1000 registered cases Less than 2 complications of any kind

No serious adverse events

Depends on condition being treated

In 2013- we can cryopreserve cells for future use

Active Cancer

Infection

Blood Thinners

Use patients own cells

Provide service during same operative procedure

Minimally manipulate cells

Do not promote therapy or make claims

Performed as a surgical procedure (no laboratory)

Need IRB approved (FDA registered) studies to

support valid claims

International Centers (variably reputable)

Research meetings

Anecdotal and testimonial information

Early results from clinical trials

Veterinary literature

Personal experience with our own patients in USA

(more than 300)

UNIVERSITYPHARMA LABS

FDA APPROVED TRIALS

MOSTLY BONE MARROW AND

SOME EMBRYONIC

LONG TIME FOR OUTCOMES

PATENT ISSUES

FOR INSTITUTIONAL

PROFITGOVT FUNDED

DRUG MODEL

GRASSROOTS COMMUNITY

PHYSICIANrsquoS PRACTICE

BONE MARROW AND ADIPOSE

DERIVED

RAPID CLINICAL EVALUATION

WIDESPREAD AVAILABILITY

NO PATENTS NEEDED

FOR PROFITPATIENT FUNDED

NOT ldquoDRUG ORIENTEDrdquo

CSN In Association with theCalifornia Stem Cell Treatment Center

International research sharing protocols and database including Asia and Canada

High numbers of fresh autologous cells for various degenerative conditions

Standardized Multispecialty care

Advanced deployment methods

Quality Stem Cell Therapy should be available everywhere and easily accessible

WWWSTEMCELLREVOLUTIONCOM

After Three Months

Wanted to share with you the news

I was just released from my eye therapy

I am still waiting on the prism sticker for

my glasses but no more eye patch

After Four Months

I am doing GREAT I have full

vision back and havenrsquot taken my

MS shots since January

After Five Months

This is one Happy Girl

Just left my neurologist and no signs of MS for this Girl

Indiana Stem Cell Treatment CenterDr Robert F Jackson amp Dr Chris Lowery

9660 East 146th Street Suite 100

Noblesville IN 46060

317-773-6677 or 800-708-2462

wwwindianastemcelltreatmentcentercom

Thank you for your Attention

By far the most common type of hair restoration procedure

Involves surgery to the back of the scalp that results in a large scar

The scar will be visible with short hair Significant downtime and pain Typically good results

CRITICAL LIMB ISCHEMIA

WOUND CARE

TMJ SYNDROME

LICHEN SCLEROSIS

ANTI-AGEING

Over 300 cases with one complication

No documented cases of serious injury in human

or animals

International Stem Cell Society (ISCS) ndash reported

over 1000 registered cases Less than 2 complications of any kind

No serious adverse events

Depends on condition being treated

In 2013- we can cryopreserve cells for future use

Active Cancer

Infection

Blood Thinners

Use patients own cells

Provide service during same operative procedure

Minimally manipulate cells

Do not promote therapy or make claims

Performed as a surgical procedure (no laboratory)

Need IRB approved (FDA registered) studies to

support valid claims

International Centers (variably reputable)

Research meetings

Anecdotal and testimonial information

Early results from clinical trials

Veterinary literature

Personal experience with our own patients in USA

(more than 300)

UNIVERSITYPHARMA LABS

FDA APPROVED TRIALS

MOSTLY BONE MARROW AND

SOME EMBRYONIC

LONG TIME FOR OUTCOMES

PATENT ISSUES

FOR INSTITUTIONAL

PROFITGOVT FUNDED

DRUG MODEL

GRASSROOTS COMMUNITY

PHYSICIANrsquoS PRACTICE

BONE MARROW AND ADIPOSE

DERIVED

RAPID CLINICAL EVALUATION

WIDESPREAD AVAILABILITY

NO PATENTS NEEDED

FOR PROFITPATIENT FUNDED

NOT ldquoDRUG ORIENTEDrdquo

CSN In Association with theCalifornia Stem Cell Treatment Center

International research sharing protocols and database including Asia and Canada

High numbers of fresh autologous cells for various degenerative conditions

Standardized Multispecialty care

Advanced deployment methods

Quality Stem Cell Therapy should be available everywhere and easily accessible

WWWSTEMCELLREVOLUTIONCOM

After Three Months

Wanted to share with you the news

I was just released from my eye therapy

I am still waiting on the prism sticker for

my glasses but no more eye patch

After Four Months

I am doing GREAT I have full

vision back and havenrsquot taken my

MS shots since January

After Five Months

This is one Happy Girl

Just left my neurologist and no signs of MS for this Girl

Indiana Stem Cell Treatment CenterDr Robert F Jackson amp Dr Chris Lowery

9660 East 146th Street Suite 100

Noblesville IN 46060

317-773-6677 or 800-708-2462

wwwindianastemcelltreatmentcentercom

Thank you for your Attention

CRITICAL LIMB ISCHEMIA

WOUND CARE

TMJ SYNDROME

LICHEN SCLEROSIS

ANTI-AGEING

Over 300 cases with one complication

No documented cases of serious injury in human

or animals

International Stem Cell Society (ISCS) ndash reported

over 1000 registered cases Less than 2 complications of any kind

No serious adverse events

Depends on condition being treated

In 2013- we can cryopreserve cells for future use

Active Cancer

Infection

Blood Thinners

Use patients own cells

Provide service during same operative procedure

Minimally manipulate cells

Do not promote therapy or make claims

Performed as a surgical procedure (no laboratory)

Need IRB approved (FDA registered) studies to

support valid claims

International Centers (variably reputable)

Research meetings

Anecdotal and testimonial information

Early results from clinical trials

Veterinary literature

Personal experience with our own patients in USA

(more than 300)

UNIVERSITYPHARMA LABS

FDA APPROVED TRIALS

MOSTLY BONE MARROW AND

SOME EMBRYONIC

LONG TIME FOR OUTCOMES

PATENT ISSUES

FOR INSTITUTIONAL

PROFITGOVT FUNDED

DRUG MODEL

GRASSROOTS COMMUNITY

PHYSICIANrsquoS PRACTICE

BONE MARROW AND ADIPOSE

DERIVED

RAPID CLINICAL EVALUATION

WIDESPREAD AVAILABILITY

NO PATENTS NEEDED

FOR PROFITPATIENT FUNDED

NOT ldquoDRUG ORIENTEDrdquo

CSN In Association with theCalifornia Stem Cell Treatment Center

International research sharing protocols and database including Asia and Canada

High numbers of fresh autologous cells for various degenerative conditions

Standardized Multispecialty care

Advanced deployment methods

Quality Stem Cell Therapy should be available everywhere and easily accessible

WWWSTEMCELLREVOLUTIONCOM

After Three Months

Wanted to share with you the news

I was just released from my eye therapy

I am still waiting on the prism sticker for

my glasses but no more eye patch

After Four Months

I am doing GREAT I have full

vision back and havenrsquot taken my

MS shots since January

After Five Months

This is one Happy Girl

Just left my neurologist and no signs of MS for this Girl

Indiana Stem Cell Treatment CenterDr Robert F Jackson amp Dr Chris Lowery

9660 East 146th Street Suite 100

Noblesville IN 46060

317-773-6677 or 800-708-2462

wwwindianastemcelltreatmentcentercom

Thank you for your Attention

Over 300 cases with one complication

No documented cases of serious injury in human

or animals

International Stem Cell Society (ISCS) ndash reported

over 1000 registered cases Less than 2 complications of any kind

No serious adverse events

Depends on condition being treated

In 2013- we can cryopreserve cells for future use

Active Cancer

Infection

Blood Thinners

Use patients own cells

Provide service during same operative procedure

Minimally manipulate cells

Do not promote therapy or make claims

Performed as a surgical procedure (no laboratory)

Need IRB approved (FDA registered) studies to

support valid claims

International Centers (variably reputable)

Research meetings

Anecdotal and testimonial information

Early results from clinical trials

Veterinary literature

Personal experience with our own patients in USA

(more than 300)

UNIVERSITYPHARMA LABS

FDA APPROVED TRIALS

MOSTLY BONE MARROW AND

SOME EMBRYONIC

LONG TIME FOR OUTCOMES

PATENT ISSUES

FOR INSTITUTIONAL

PROFITGOVT FUNDED

DRUG MODEL

GRASSROOTS COMMUNITY

PHYSICIANrsquoS PRACTICE

BONE MARROW AND ADIPOSE

DERIVED

RAPID CLINICAL EVALUATION

WIDESPREAD AVAILABILITY

NO PATENTS NEEDED

FOR PROFITPATIENT FUNDED

NOT ldquoDRUG ORIENTEDrdquo

CSN In Association with theCalifornia Stem Cell Treatment Center

International research sharing protocols and database including Asia and Canada

High numbers of fresh autologous cells for various degenerative conditions

Standardized Multispecialty care

Advanced deployment methods

Quality Stem Cell Therapy should be available everywhere and easily accessible

WWWSTEMCELLREVOLUTIONCOM

After Three Months

Wanted to share with you the news

I was just released from my eye therapy

I am still waiting on the prism sticker for

my glasses but no more eye patch

After Four Months

I am doing GREAT I have full

vision back and havenrsquot taken my

MS shots since January

After Five Months

This is one Happy Girl

Just left my neurologist and no signs of MS for this Girl

Indiana Stem Cell Treatment CenterDr Robert F Jackson amp Dr Chris Lowery

9660 East 146th Street Suite 100

Noblesville IN 46060

317-773-6677 or 800-708-2462

wwwindianastemcelltreatmentcentercom

Thank you for your Attention

Depends on condition being treated

In 2013- we can cryopreserve cells for future use

Active Cancer

Infection

Blood Thinners

Use patients own cells

Provide service during same operative procedure

Minimally manipulate cells

Do not promote therapy or make claims

Performed as a surgical procedure (no laboratory)

Need IRB approved (FDA registered) studies to

support valid claims

International Centers (variably reputable)

Research meetings

Anecdotal and testimonial information

Early results from clinical trials

Veterinary literature

Personal experience with our own patients in USA

(more than 300)

UNIVERSITYPHARMA LABS

FDA APPROVED TRIALS

MOSTLY BONE MARROW AND

SOME EMBRYONIC

LONG TIME FOR OUTCOMES

PATENT ISSUES

FOR INSTITUTIONAL

PROFITGOVT FUNDED

DRUG MODEL

GRASSROOTS COMMUNITY

PHYSICIANrsquoS PRACTICE

BONE MARROW AND ADIPOSE

DERIVED

RAPID CLINICAL EVALUATION

WIDESPREAD AVAILABILITY

NO PATENTS NEEDED

FOR PROFITPATIENT FUNDED

NOT ldquoDRUG ORIENTEDrdquo

CSN In Association with theCalifornia Stem Cell Treatment Center

International research sharing protocols and database including Asia and Canada

High numbers of fresh autologous cells for various degenerative conditions

Standardized Multispecialty care

Advanced deployment methods

Quality Stem Cell Therapy should be available everywhere and easily accessible

WWWSTEMCELLREVOLUTIONCOM

After Three Months

Wanted to share with you the news

I was just released from my eye therapy

I am still waiting on the prism sticker for

my glasses but no more eye patch

After Four Months

I am doing GREAT I have full

vision back and havenrsquot taken my

MS shots since January

After Five Months

This is one Happy Girl

Just left my neurologist and no signs of MS for this Girl

Indiana Stem Cell Treatment CenterDr Robert F Jackson amp Dr Chris Lowery

9660 East 146th Street Suite 100

Noblesville IN 46060

317-773-6677 or 800-708-2462

wwwindianastemcelltreatmentcentercom

Thank you for your Attention

Active Cancer

Infection

Blood Thinners

Use patients own cells

Provide service during same operative procedure

Minimally manipulate cells

Do not promote therapy or make claims

Performed as a surgical procedure (no laboratory)

Need IRB approved (FDA registered) studies to

support valid claims

International Centers (variably reputable)

Research meetings

Anecdotal and testimonial information

Early results from clinical trials

Veterinary literature

Personal experience with our own patients in USA

(more than 300)

UNIVERSITYPHARMA LABS

FDA APPROVED TRIALS

MOSTLY BONE MARROW AND

SOME EMBRYONIC

LONG TIME FOR OUTCOMES

PATENT ISSUES

FOR INSTITUTIONAL

PROFITGOVT FUNDED

DRUG MODEL

GRASSROOTS COMMUNITY

PHYSICIANrsquoS PRACTICE

BONE MARROW AND ADIPOSE

DERIVED

RAPID CLINICAL EVALUATION

WIDESPREAD AVAILABILITY

NO PATENTS NEEDED

FOR PROFITPATIENT FUNDED

NOT ldquoDRUG ORIENTEDrdquo

CSN In Association with theCalifornia Stem Cell Treatment Center

International research sharing protocols and database including Asia and Canada

High numbers of fresh autologous cells for various degenerative conditions

Standardized Multispecialty care

Advanced deployment methods

Quality Stem Cell Therapy should be available everywhere and easily accessible

WWWSTEMCELLREVOLUTIONCOM

After Three Months

Wanted to share with you the news

I was just released from my eye therapy

I am still waiting on the prism sticker for

my glasses but no more eye patch

After Four Months

I am doing GREAT I have full

vision back and havenrsquot taken my

MS shots since January

After Five Months

This is one Happy Girl

Just left my neurologist and no signs of MS for this Girl

Indiana Stem Cell Treatment CenterDr Robert F Jackson amp Dr Chris Lowery

9660 East 146th Street Suite 100

Noblesville IN 46060

317-773-6677 or 800-708-2462

wwwindianastemcelltreatmentcentercom

Thank you for your Attention

Use patients own cells

Provide service during same operative procedure

Minimally manipulate cells

Do not promote therapy or make claims

Performed as a surgical procedure (no laboratory)

Need IRB approved (FDA registered) studies to

support valid claims

International Centers (variably reputable)

Research meetings

Anecdotal and testimonial information

Early results from clinical trials

Veterinary literature

Personal experience with our own patients in USA

(more than 300)

UNIVERSITYPHARMA LABS

FDA APPROVED TRIALS

MOSTLY BONE MARROW AND

SOME EMBRYONIC

LONG TIME FOR OUTCOMES

PATENT ISSUES

FOR INSTITUTIONAL

PROFITGOVT FUNDED

DRUG MODEL

GRASSROOTS COMMUNITY

PHYSICIANrsquoS PRACTICE

BONE MARROW AND ADIPOSE

DERIVED

RAPID CLINICAL EVALUATION

WIDESPREAD AVAILABILITY

NO PATENTS NEEDED

FOR PROFITPATIENT FUNDED

NOT ldquoDRUG ORIENTEDrdquo

CSN In Association with theCalifornia Stem Cell Treatment Center

International research sharing protocols and database including Asia and Canada

High numbers of fresh autologous cells for various degenerative conditions

Standardized Multispecialty care

Advanced deployment methods

Quality Stem Cell Therapy should be available everywhere and easily accessible

WWWSTEMCELLREVOLUTIONCOM

After Three Months

Wanted to share with you the news

I was just released from my eye therapy

I am still waiting on the prism sticker for

my glasses but no more eye patch

After Four Months

I am doing GREAT I have full

vision back and havenrsquot taken my

MS shots since January

After Five Months

This is one Happy Girl

Just left my neurologist and no signs of MS for this Girl

Indiana Stem Cell Treatment CenterDr Robert F Jackson amp Dr Chris Lowery

9660 East 146th Street Suite 100

Noblesville IN 46060

317-773-6677 or 800-708-2462

wwwindianastemcelltreatmentcentercom

Thank you for your Attention

Need IRB approved (FDA registered) studies to

support valid claims

International Centers (variably reputable)

Research meetings

Anecdotal and testimonial information

Early results from clinical trials

Veterinary literature

Personal experience with our own patients in USA

(more than 300)

UNIVERSITYPHARMA LABS

FDA APPROVED TRIALS

MOSTLY BONE MARROW AND

SOME EMBRYONIC

LONG TIME FOR OUTCOMES

PATENT ISSUES

FOR INSTITUTIONAL

PROFITGOVT FUNDED

DRUG MODEL

GRASSROOTS COMMUNITY

PHYSICIANrsquoS PRACTICE

BONE MARROW AND ADIPOSE

DERIVED

RAPID CLINICAL EVALUATION

WIDESPREAD AVAILABILITY

NO PATENTS NEEDED

FOR PROFITPATIENT FUNDED

NOT ldquoDRUG ORIENTEDrdquo

CSN In Association with theCalifornia Stem Cell Treatment Center

International research sharing protocols and database including Asia and Canada

High numbers of fresh autologous cells for various degenerative conditions

Standardized Multispecialty care

Advanced deployment methods

Quality Stem Cell Therapy should be available everywhere and easily accessible

WWWSTEMCELLREVOLUTIONCOM

After Three Months

Wanted to share with you the news

I was just released from my eye therapy

I am still waiting on the prism sticker for

my glasses but no more eye patch

After Four Months

I am doing GREAT I have full

vision back and havenrsquot taken my

MS shots since January

After Five Months

This is one Happy Girl

Just left my neurologist and no signs of MS for this Girl

Indiana Stem Cell Treatment CenterDr Robert F Jackson amp Dr Chris Lowery

9660 East 146th Street Suite 100

Noblesville IN 46060

317-773-6677 or 800-708-2462

wwwindianastemcelltreatmentcentercom

Thank you for your Attention

UNIVERSITYPHARMA LABS

FDA APPROVED TRIALS

MOSTLY BONE MARROW AND

SOME EMBRYONIC

LONG TIME FOR OUTCOMES

PATENT ISSUES

FOR INSTITUTIONAL

PROFITGOVT FUNDED

DRUG MODEL

GRASSROOTS COMMUNITY

PHYSICIANrsquoS PRACTICE

BONE MARROW AND ADIPOSE

DERIVED

RAPID CLINICAL EVALUATION

WIDESPREAD AVAILABILITY

NO PATENTS NEEDED

FOR PROFITPATIENT FUNDED

NOT ldquoDRUG ORIENTEDrdquo

CSN In Association with theCalifornia Stem Cell Treatment Center

International research sharing protocols and database including Asia and Canada

High numbers of fresh autologous cells for various degenerative conditions

Standardized Multispecialty care

Advanced deployment methods

Quality Stem Cell Therapy should be available everywhere and easily accessible

WWWSTEMCELLREVOLUTIONCOM

After Three Months

Wanted to share with you the news

I was just released from my eye therapy

I am still waiting on the prism sticker for

my glasses but no more eye patch

After Four Months

I am doing GREAT I have full

vision back and havenrsquot taken my

MS shots since January

After Five Months

This is one Happy Girl

Just left my neurologist and no signs of MS for this Girl

Indiana Stem Cell Treatment CenterDr Robert F Jackson amp Dr Chris Lowery

9660 East 146th Street Suite 100

Noblesville IN 46060

317-773-6677 or 800-708-2462

wwwindianastemcelltreatmentcentercom

Thank you for your Attention

CSN In Association with theCalifornia Stem Cell Treatment Center

International research sharing protocols and database including Asia and Canada

High numbers of fresh autologous cells for various degenerative conditions

Standardized Multispecialty care

Advanced deployment methods

Quality Stem Cell Therapy should be available everywhere and easily accessible

WWWSTEMCELLREVOLUTIONCOM

After Three Months

Wanted to share with you the news

I was just released from my eye therapy

I am still waiting on the prism sticker for

my glasses but no more eye patch

After Four Months

I am doing GREAT I have full

vision back and havenrsquot taken my

MS shots since January

After Five Months

This is one Happy Girl

Just left my neurologist and no signs of MS for this Girl

Indiana Stem Cell Treatment CenterDr Robert F Jackson amp Dr Chris Lowery

9660 East 146th Street Suite 100

Noblesville IN 46060

317-773-6677 or 800-708-2462

wwwindianastemcelltreatmentcentercom

Thank you for your Attention

International research sharing protocols and database including Asia and Canada

High numbers of fresh autologous cells for various degenerative conditions

Standardized Multispecialty care

Advanced deployment methods

Quality Stem Cell Therapy should be available everywhere and easily accessible

WWWSTEMCELLREVOLUTIONCOM

After Three Months

Wanted to share with you the news

I was just released from my eye therapy

I am still waiting on the prism sticker for

my glasses but no more eye patch

After Four Months

I am doing GREAT I have full

vision back and havenrsquot taken my

MS shots since January

After Five Months

This is one Happy Girl

Just left my neurologist and no signs of MS for this Girl

Indiana Stem Cell Treatment CenterDr Robert F Jackson amp Dr Chris Lowery

9660 East 146th Street Suite 100

Noblesville IN 46060

317-773-6677 or 800-708-2462

wwwindianastemcelltreatmentcentercom

Thank you for your Attention

WWWSTEMCELLREVOLUTIONCOM

After Three Months

Wanted to share with you the news

I was just released from my eye therapy

I am still waiting on the prism sticker for

my glasses but no more eye patch

After Four Months

I am doing GREAT I have full

vision back and havenrsquot taken my

MS shots since January

After Five Months

This is one Happy Girl

Just left my neurologist and no signs of MS for this Girl

Indiana Stem Cell Treatment CenterDr Robert F Jackson amp Dr Chris Lowery

9660 East 146th Street Suite 100

Noblesville IN 46060

317-773-6677 or 800-708-2462

wwwindianastemcelltreatmentcentercom

Thank you for your Attention

After Three Months

Wanted to share with you the news

I was just released from my eye therapy

I am still waiting on the prism sticker for

my glasses but no more eye patch

After Four Months

I am doing GREAT I have full

vision back and havenrsquot taken my

MS shots since January

After Five Months

This is one Happy Girl

Just left my neurologist and no signs of MS for this Girl

Indiana Stem Cell Treatment CenterDr Robert F Jackson amp Dr Chris Lowery

9660 East 146th Street Suite 100

Noblesville IN 46060

317-773-6677 or 800-708-2462

wwwindianastemcelltreatmentcentercom

Thank you for your Attention

After Four Months

I am doing GREAT I have full

vision back and havenrsquot taken my

MS shots since January

After Five Months

This is one Happy Girl

Just left my neurologist and no signs of MS for this Girl

Indiana Stem Cell Treatment CenterDr Robert F Jackson amp Dr Chris Lowery

9660 East 146th Street Suite 100

Noblesville IN 46060

317-773-6677 or 800-708-2462

wwwindianastemcelltreatmentcentercom

Thank you for your Attention

After Five Months

This is one Happy Girl

Just left my neurologist and no signs of MS for this Girl

Indiana Stem Cell Treatment CenterDr Robert F Jackson amp Dr Chris Lowery

9660 East 146th Street Suite 100

Noblesville IN 46060

317-773-6677 or 800-708-2462

wwwindianastemcelltreatmentcentercom

Thank you for your Attention

Indiana Stem Cell Treatment CenterDr Robert F Jackson amp Dr Chris Lowery

9660 East 146th Street Suite 100

Noblesville IN 46060

317-773-6677 or 800-708-2462

wwwindianastemcelltreatmentcentercom

Thank you for your Attention