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REGULAROTY NEEDS – ENDOCRINE: CONCEPT OF METABOLISM The collec(on of biochemical reac(ons that occur in body cells to produce energy, repair cells, and maintain life Hormones secreted by endocrine glands Fall 2019 Spring 2020 1

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Page 1: REGULAROTY*NEEDS*– ENDOCRINE:*CONCEPT* OFMETABOLISMlahc323325.weebly.com/uploads/1/1/0/6/110686185/... · REGULATORY$NEEDS:$DIAGNOSTIC$ STUDIES$ • SERUMLABS: $ Thyroid>s(mulang$hormone$

REGULAROTY  NEEDS  –ENDOCRINE:  CONCEPT  OF  METABOLISM  

•  The  collec(on  of  biochemical  reac(ons  that  occur  in  body  cells  to  produce  energy,  repair  cells,  and  maintain  life  

•  Hormones  secreted  by  endocrine  glands  

Fall  2019  -­‐  Spring  2020   1  

Page 2: REGULAROTY*NEEDS*– ENDOCRINE:*CONCEPT* OFMETABOLISMlahc323325.weebly.com/uploads/1/1/0/6/110686185/... · REGULATORY$NEEDS:$DIAGNOSTIC$ STUDIES$ • SERUMLABS: $ Thyroid>s(mulang$hormone$

CONCEPTS  RELATED  TO  METABOLISM  

•  Diabetes  Mellitus  •  Syndrome  of  Inappropriate  An(diure(c  Hormone  (SIADH)  

•  Diabetes  Insipidus  (DI)  •  Hyperthyroidism  •  Hypothyroidism  •  Hyperparathyroidism  •  Hypoparathyroidism  •  Cushing  Syndrome  •  Addison’s  Disease  

•  Fluid  &  Electrolytes  •  Mobility  •  Perfusion  •  Reproduc)on  •  Stress  &  Coping  

 (Collabora(on)  *Describe  each        concept  *What  nursing  physical  assessments  are  involved?  

Fall  2019  -­‐  Spring  2020   2  

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Fall  2019  -­‐  Spring  2020   3  

CONCEPT   RELATIONSHIP  TO  METABOLISM    

NURSING  IMPLICATIONS  

F  &  E   §  é  Aldosterone  produc(on  èéNa+  &  H2O  reten(on  è  fluid  excess  è  edema  

§  Dehydra(on  and  hypovolemia  èéADH  hormone  and    

é  aldosterone  è              Na+  &  H20  reten(on  §  Metabolic  disorders  (e.g.  

Cushing  syndrome,  DI)  è  hypernatremia  

§  Adrenal  insufficiency  è  hyponatremia  &  hyperkalemia    

§  Fluid  deficit/excess    excess  will  cause  changes  in  VS  

§  Assess  skin  turgor,  UOP,  urine  specific  gravity,  weight  

§  Monitor  older  adults  closely  for  dehydra(on  

§  For  older  adults,  changes  in  fluid  may  cause  changes  in  mental  status  

§  Monitor  F&E  levels  

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Fall  2019  -­‐  Spring  2020   4  

CONCEPT   RELATIONSHIP  TO  METABOLISM  

NURSING  IMPLICATIONS  

Mobility   §  êCa+  è  ê  bone  density  è  é  bone  fractures  è    

ê  mobility  

§  Older  adults  with  low  Ca+  or  low  bone  density  should  be  monitored  for  risk  for  falls,  which  lead  to  bone  fractures,  especially  hips  

§  Individuals  with  bone  fractures  should  be  instructed  to  consume  adequate  levels  of  calcium  to  promote  calcium  deposi(on  in  bones  

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Fall  2019  -­‐  Spring  2020   5  

CONCEPT   RELATIONSHIP  TO  METABOLISM  

NURSING  IMPLICATIONS  

Perfusion   §  é  Aldosterone  è  éNa+  &  H2O  reten(on  èépreload  èéoverstretching  of  heart  muscle  è  ineffec(ve  heart  contrac(on  è  heart  failure  

§  é  Aldosterone  è  éNa+  &  H2O  reten(on  èé  blood  volume  èéBP  

§  êAldosterone  èêNa+  &  H20  reten(on  è  fluid  deficit  èêpreloadèêCOèéHR  &  êBP  

§  Regula(on  of  electrolytes  by  hormones  è  ion  availability  èheart  muscle  contrac(on  

§  Closely  monitor  pa(ents  with  altera(ons  in  metabolism  for  change  in  perfusion  

§  Closely  monitor  HR  and  BP,  because  change  in  these  VS  are  ocen  early  signs  of  problems  

§  Monitor  I&O,  water  and  electrolyte  levels,  edema,  as  they  can  radically  alter  blood  volume  and  heart  workload  

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Fall  2019  -­‐  Spring  2020   6  

CONCEPT   RELATIONSHIP  TO  METABOLISM  

NURSING  IMPLICATIONS  

Perfusion  (con’t)  

§  Thyrotoxicosis/hyperthyroidism  è myocardial  oxygen  demand  è angina  

§  Hypothyroidism  èévascular  resistance  èéBP  

§  Ischemia  of  heart  vessels  è  electrolyte  imbalances  and  hormone  release  èêmyocardial  contrac(lity  èêCO,  êBP,  and  ê(ssue  perfusion  

§  Insulin  resistance  èDMèéBP  and  obesityèérisk  of  stroke  

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Fall  2019  -­‐  Spring  2020   7  

CONCEPT   RELATIONSHIP  TO  METABOLISM  

NURSING  IMPLICATIONS  

Stress  &  Coping  

§  éStressèécor(solè êinflammatory  response  and  changes  in  metabolism  of  carbohydrates  and  fats  

§  All  assessments  related  to  metabolic  disorders  should  also  include  as  assessment  of  the  pa(ent’s  stress  level  and  coping  ability  

Collabora)on     §  Pa(ents  with  endocrine  or  metabolic  disorders  may  have  comorbidi(es  that  require  care  by  mul(ple  healthcare  providers  

§  Many  metabolic  disorders  are  rare  and  may  require  working  with  a  specialist;  some  may  require  surgery,  which  requires  working  with  a  surgical  team  and  others  

§  Advocate  for  pa(ents  with  metabolic  disorders  to  receive  care  by  the  appropriate  specialist  

§  Maintain  adequate  communica(on  among  all  healthcare  providers  to  develop  a  complete  understanding  of  the  pa(ent’s  condi(on(s)  

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Gerontologic  Considera(ons  Effects  of  Aging  on  Endocrine  System    

•  Decreased  production  and  secretion  •  Altered  metabolism  and  biologic  activity  •  Decreased  responsiveness    •  Assessment  difficult  •  Co-­‐morbid  conditions  and  medications  alter  response  

Fall  2019  -­‐  Spring  2020   8  

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Assessment  of  Endocrine  System  •  Dysfunction:  too  much  or  too  little  of  a  

hormone  – Onset  of  symptoms  is  often  gradual  – Vague  symptoms  can  be  misinterpreted  – Many  metabolic  disorders  are  not  observable  

•  Therefore,  nurse  should  be  aware  of  visible  signs  associated  with  metabolic  disorders  

Fall  2019  -­‐  Spring  2020   9  

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Fall  2019  -­‐  Spring  2020   10  

Central  Obesity  

Graves’  Disease  

   Goiter  

       Abdominal  Striae  Careful  interview  focusing  on  chief  complaint  (e.g.  change  in:  body  weight  (gain/loss),  skin  color,  texture,  increased  urina(on,  energy  levels,  menstrual  cycle,  memory,  feelings  of  anxiety,  restlessness,  confused,  heart  palpita(ons,  pain/s(ff  muscle  joints  +  many  more  

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Assessment  of  Endocrine  System  

•  Those  who  present  with  acute  symptoms  may  need  immediate  intervention  for  life-­‐threatening  conditions  – What  conditions  r/t  this  system  and  the  concepts  of  metabolism  do  you  consider  are  life-­‐threatening?  

Fall  2019  -­‐  Spring  2020   11  

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REGULATORY  NEEDS:  DIAGNOSTIC  STUDIES  

•  SERUM  LABS:  Thyroid-­‐s(mula(ng  hormone  (TSH),Triiodothyronine  (T3),  Thyroxine  (T4),  Free  thyroxine  (FT4),  Thyroid  an(bodies,  Thyroglubulin;  Parathyroid  hormone  (PTH),  Calcium(total/ionized),  Phosphate;  Cor(sol,  Aldosterone,  Adrenocor(cotropic  hormone  (ACTH),  ACTH  s(mula(on/suppression;  Fas(ng  blood  glucose,  Oral  glucose  tolerance  test,  Glycosylated  hemoglobin  (A1C);  Serum  electrolytes    

•  URINE  ANALYSIS:  Glucose,  Ketones  

•  RADIOLOGIC  STUDIES:  Computed  tomography  (CT),  Magne(c  resonance  imaging  (MRI),  Ultrasound(US),  Thyroid/Parathyroid  Scan  

Fall  2019  -­‐  Spring  2020   12