relationship of organic chemistry
DESCRIPTION
biochemistryTRANSCRIPT
Relationship of Organic Chemistry to Biochemistry
Rondang R. Soegianto 2014
Chemistry is the Study of Matter
and its Changes
- What is matter?
- What are the changes?
BIOCHEMISTRY = LIFE SCIENCE
Chemistry of living system related to
Functions and Needs of the system
Matter changes thru chemical reactions
Atoms interact to form a bond =
Chemical bonding
- Ionic bonds
- Covalent bonds
Ionic Bonds
Atoms that loses e- pos ion (cation)
Atom that acquires e- neg ion (anion)
Ex. Ca + 2 Cl CaCl2
Covalent Bond
Sharing of a pair of electrons between atoms
Ex. H2 , CH4
BIOLOGICAL COMPOUNDS
Molecules of the body mainly:C, H, O, N, S, P
Joined by covalent bondsC is key element, forms covalent bondWith C, H, O, N, S
P usually linked to C by an oxygen atom.
FUNCTIONAL GROUPS
- Carbon-Oxygen groups- Carbon-Sulfur groups- Carbon-Nitrogen groups- Esters and Amides
Gambar 5.2a
Gambar 5.2b
Gambar 5.2c
KETONE BODIES are synthesized in the liver as acetoacetic acid andβ-hydroxybutiric acid.
At physiological pH they formtheir conjugate bases Acetoacetate and β-Hydroxybutirate
Gambar 4 Hal. 44
Groups That Carry a Charge
Acidic groups contain a proton that candissociate negative charge
Compouds containing N usually BASICand may acquire positive charge
Gambar Fig. 53
Gambar Fig. 54
REACTIVITY
Atoms with neg charge will be attracted
to atoms with pos charge and vice versa
Gambar Fig. 5.6
Gambar Fig. 5.7a (5)
Gambar Fig. 5.7b (6)
Gambar Fig. 5.8
Gambar Fig. 5.9
Gambar Fig. 5.10
Gambar Fig. 5.11
Gambar Fig. 5.12
Gambar Fig. 5.13
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