renal failure (abeer 1)

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    Kidney Failure

    Prepared by:

    Dr. Abeer M. Aly

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    Dr. Abeer M. Aly 2

    Definition:

    Renal failure means, inabilityof the renal system to

    perform its normal functions.

    What are the normal functionsof the renal system???

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    Dr. Abeer M. Aly 3

    Functions of urinary system:

    1. Regulate blood volume andcomposition.2. Help regulate blood pressure.3. Regulation of blood glucose level.4. Excretion of wastes and foreignsubstances.5. Regulation of blood PH.6. Production of hormones(Erythropoietin, Calcitriol)

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    Blood pressure forces water, glucose, aminoacids and urea from capillaries into

    nephron

    Glucose and amino acids are reabsorbed intoblood from nephron

    Some water is reabsorbed into blood

    Urine is urea and salt concentrated in water

    Urine Formation by Nephron

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    Definition:The inability of nephrons to:

    Maintain fluid, electrolyte, & acid-

    base balance,Excrete nitrogen waste products,

    Regulate calcium in bones,

    Produce erythropoietin.

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    Dr. Abeer M. Aly 10

    Acute Renal Failure

    Acute Renal FailureIs a sudden, usually reversible

    deterioration in normal renalfunction.

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    Dr. Abeer M. Aly 11

    Causes of acute renal failure:

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    Dr. Abeer M. Aly 12

    Causes of renal failure:

    1. Prerenal causes:

    a. Hypovolemia.

    b. Impaired cardiac efficiency.

    c. Vasodilatation.

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    Dr. Abeer M. Aly 13

    2. Postrenal obstruction:a. Urinary tract obstruction.

    b. Tumors.3. Intrarenal:

    a. Acute nephritis.

    b. Antibiotics.c. NSAIDs.

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    Dr. Abeer M. Aly 14

    Causes of acute renal failure:-

    Pre Renal Renal Post Renal

    Hypovolemia

    Drugs

    Toxins

    Multiple-organfailure

    polycystic

    kidney disease

    A.pyelonephritis

    A.gloumerulnephritis

    Tumor

    Calculi

    Stricture

    Prostatichypertrophy

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    Dr. Abeer M. Aly 15

    Phases:-

    Initiation phase:- (1-2 days)

    The time from renal insult torecognition of decrease

    Glomerular Filtration Rate (GFR).

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    Dr. Abeer M. Aly 16

    Oliguric phase ( maintenancephase 1-2 week)

    -The period of time during which oliguriapersists .

    - It is most life threatening period(Hyperkalemia)

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    Dr. Abeer M. Aly 17

    Polyuric phase:- Diuretic phase

    Progressive increase in urine

    volume.

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    Dr. Abeer M. Aly 18

    Functional recovery phase:-

    3-12 months, The patientrepairing the renal injury &return to normal.

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    Dr. Abeer M. Aly 19

    Chronic Renal Failure:-

    Is progressive , irreversible

    deterioration in renal

    function.

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    Dr. Abeer M. Aly 20

    Acute- sudden onset

    - reversible- Tubular cell death

    and regeneration

    oChronic

    oProgressive

    oNot reversible

    oNephron loss

    Acute Versus Chronic

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    Dr. Abeer M. Aly 21

    Signs & Symptoms:-

    Urine analysis.

    Hydration condition.

    Vital Signs.

    GIT manifestations..

    Investigations.

    CNS manifestations..

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    Dr. Abeer M. Aly 22

    Investigation:

    A urine analysislevels progressively increase Creatinine

    is progressively increased BUN

    progressively decreases Creatinine clearance

    may show elevated levels Potassium test

    Arterial blood gas and blood chemistryanalysis may show metabolic acidosis

    http://www.nlm.nih.gov/medlineplus/ency/article/003474.htmhttp://www.nlm.nih.gov/medlineplus/ency/article/003611.htmhttp://www.nlm.nih.gov/medlineplus/ency/article/003484.htmhttp://www.nlm.nih.gov/medlineplus/ency/article/003468.htmhttp://www.nlm.nih.gov/medlineplus/ency/article/003468.htmhttp://www.nlm.nih.gov/medlineplus/ency/article/003484.htmhttp://www.nlm.nih.gov/medlineplus/ency/article/003611.htmhttp://www.nlm.nih.gov/medlineplus/ency/article/003474.htm
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    Dr. Abeer M. Aly 23

    Radiological investigations

    Abdominal ultrasounds

    Abdominal CT scan

    Abdominal MRI scan

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    Dr. Abeer M. Aly 24

    Management:-

    1. prevention.

    Treatment:-

    1. Renal replacement therapy.

    2. Monitor serum electrolyte level.

    3. Control hemodynamic condition.

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    Dr. Abeer M. Aly 25

    Nursing Diagnosis:-

    Activity Intolerance.

    Fluid Volume Excess & electrolyteimbalance

    Self esteem disturbance.

    Knowledge Deficit.

    Altered nutrition less than bodyrequirement.

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    Dr. Abeer M. Aly 26

    Diet.

    Activity.

    Care of the vascular access.

    Personal Hygiene.

    Follow up.

    Psychological Care.

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    Dr. Abeer M. Aly 27

    An optimum dietary program is

    important for patients onRenal failure.

    The diet usually involves some

    adjustment or restriction of :-

    Protein , Sodium , Potassium or fluidintake.

    Diet

    Increase CHO in diet

    A ti it

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    Dr. Abeer M. Aly 28

    Activity:-

    The nurse should inform patient about:-

    Importance of exercise.

    Type of exercise, ( flexibility ex.,

    strengthening ex., aerobic or

    endurance ex.)

    Frequency & duration of Ex.

    When exercise must be stopped.

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    Preparation for of the vascular access.

    Personal Hygiene.

    Psychological&

    spiritual care Care.

    C li i

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    Complications

    -End- stage renal diseasePericarditis

    Cardiac tamponade

    Congestive he0art failure

    Hypertension

    Platelet dysfunctionLoss of blood from the gastrointestinal tract

    http://www.nlm.nih.gov/medlineplus/ency/article/000500.htmhttp://www.nlm.nih.gov/medlineplus/ency/article/000182.htmhttp://www.nlm.nih.gov/medlineplus/ency/article/000194.htmhttp://www.nlm.nih.gov/medlineplus/ency/article/000158.htmhttp://www.nlm.nih.gov/medlineplus/ency/article/000158.htmhttp://www.nlm.nih.gov/medlineplus/ency/article/000158.htmhttp://www.nlm.nih.gov/medlineplus/ency/article/000468.htmhttp://www.nlm.nih.gov/medlineplus/ency/article/000468.htmhttp://www.nlm.nih.gov/medlineplus/ency/article/000158.htmhttp://www.nlm.nih.gov/medlineplus/ency/article/000158.htmhttp://www.nlm.nih.gov/medlineplus/ency/article/000158.htmhttp://www.nlm.nih.gov/medlineplus/ency/article/000194.htmhttp://www.nlm.nih.gov/medlineplus/ency/article/000182.htmhttp://www.nlm.nih.gov/medlineplus/ency/article/000500.htm
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    Ulcers

    Hemorrhage

    Anemia

    Hepatitis B, Hepatitis C, liver failure

    Decreased functioning of white blood cells

    Decreased immune response

    of infection Increased incidence

    Peripheral neuropathy

    http://www.nlm.nih.gov/medlineplus/ency/article/003228.htmhttp://www.nlm.nih.gov/medlineplus/ency/article/000560.htmhttp://www.nlm.nih.gov/medlineplus/ency/article/000279.htmhttp://www.nlm.nih.gov/medlineplus/ency/article/000284.htmhttp://www.nlm.nih.gov/medlineplus/ency/article/000821.htmhttp://www.nlm.nih.gov/medlineplus/ency/article/002387.htmhttp://www.nlm.nih.gov/medlineplus/ency/article/000593.htmhttp://www.nlm.nih.gov/medlineplus/ency/article/000593.htmhttp://www.nlm.nih.gov/medlineplus/ency/article/002387.htmhttp://www.nlm.nih.gov/medlineplus/ency/article/000821.htmhttp://www.nlm.nih.gov/medlineplus/ency/article/000284.htmhttp://www.nlm.nih.gov/medlineplus/ency/article/000279.htmhttp://www.nlm.nih.gov/medlineplus/ency/article/000560.htmhttp://www.nlm.nih.gov/medlineplus/ency/article/003228.htm
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    Seizures

    Encephalopathy, nerve damage, dementia

    Weakening of the bones

    FracturesJoint disorders

    metabolism Changes in glucose

    abnormalities including Electrolyte

    hyperkalemia

    http://www.nlm.nih.gov/medlineplus/ency/article/003200.htmhttp://www.nlm.nih.gov/medlineplus/ency/article/000739.htmhttp://www.nlm.nih.gov/medlineplus/ency/article/000001.htmhttp://www.nlm.nih.gov/medlineplus/ency/article/002257.htmhttp://www.nlm.nih.gov/medlineplus/ency/article/002350.htmhttp://www.nlm.nih.gov/medlineplus/ency/article/001179.htmhttp://www.nlm.nih.gov/medlineplus/ency/article/001179.htmhttp://www.nlm.nih.gov/medlineplus/ency/article/002350.htmhttp://www.nlm.nih.gov/medlineplus/ency/article/002257.htmhttp://www.nlm.nih.gov/medlineplus/ency/article/000001.htmhttp://www.nlm.nih.gov/medlineplus/ency/article/000739.htmhttp://www.nlm.nih.gov/medlineplus/ency/article/003200.htm
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    Miscarriage, menstrual irregularities,

    infertility

    Decreased libido,impotence

    Skin dryness, itching/scratching with

    resultant skin infection .

    http://www.nlm.nih.gov/medlineplus/ency/article/001488.htmhttp://www.nlm.nih.gov/medlineplus/ency/article/003263.htmhttp://www.nlm.nih.gov/medlineplus/ency/article/001191.htmhttp://www.nlm.nih.gov/medlineplus/ency/article/003164.htmhttp://www.nlm.nih.gov/medlineplus/ency/article/003217.htmhttp://www.nlm.nih.gov/medlineplus/ency/article/003217.htmhttp://www.nlm.nih.gov/medlineplus/ency/article/003164.htmhttp://www.nlm.nih.gov/medlineplus/ency/article/001191.htmhttp://www.nlm.nih.gov/medlineplus/ency/article/003263.htmhttp://www.nlm.nih.gov/medlineplus/ency/article/001488.htm
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