renal failure (abeer 1)
TRANSCRIPT
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Kidney Failure
Prepared by:
Dr. Abeer M. Aly
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Definition:
Renal failure means, inabilityof the renal system to
perform its normal functions.
What are the normal functionsof the renal system???
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Functions of urinary system:
1. Regulate blood volume andcomposition.2. Help regulate blood pressure.3. Regulation of blood glucose level.4. Excretion of wastes and foreignsubstances.5. Regulation of blood PH.6. Production of hormones(Erythropoietin, Calcitriol)
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Blood pressure forces water, glucose, aminoacids and urea from capillaries into
nephron
Glucose and amino acids are reabsorbed intoblood from nephron
Some water is reabsorbed into blood
Urine is urea and salt concentrated in water
Urine Formation by Nephron
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Definition:The inability of nephrons to:
Maintain fluid, electrolyte, & acid-
base balance,Excrete nitrogen waste products,
Regulate calcium in bones,
Produce erythropoietin.
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Acute Renal Failure
Acute Renal FailureIs a sudden, usually reversible
deterioration in normal renalfunction.
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Causes of acute renal failure:
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Causes of renal failure:
1. Prerenal causes:
a. Hypovolemia.
b. Impaired cardiac efficiency.
c. Vasodilatation.
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2. Postrenal obstruction:a. Urinary tract obstruction.
b. Tumors.3. Intrarenal:
a. Acute nephritis.
b. Antibiotics.c. NSAIDs.
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Causes of acute renal failure:-
Pre Renal Renal Post Renal
Hypovolemia
Drugs
Toxins
Multiple-organfailure
polycystic
kidney disease
A.pyelonephritis
A.gloumerulnephritis
Tumor
Calculi
Stricture
Prostatichypertrophy
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Phases:-
Initiation phase:- (1-2 days)
The time from renal insult torecognition of decrease
Glomerular Filtration Rate (GFR).
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Oliguric phase ( maintenancephase 1-2 week)
-The period of time during which oliguriapersists .
- It is most life threatening period(Hyperkalemia)
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Polyuric phase:- Diuretic phase
Progressive increase in urine
volume.
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Functional recovery phase:-
3-12 months, The patientrepairing the renal injury &return to normal.
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Chronic Renal Failure:-
Is progressive , irreversible
deterioration in renal
function.
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Acute- sudden onset
- reversible- Tubular cell death
and regeneration
oChronic
oProgressive
oNot reversible
oNephron loss
Acute Versus Chronic
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Signs & Symptoms:-
Urine analysis.
Hydration condition.
Vital Signs.
GIT manifestations..
Investigations.
CNS manifestations..
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Investigation:
A urine analysislevels progressively increase Creatinine
is progressively increased BUN
progressively decreases Creatinine clearance
may show elevated levels Potassium test
Arterial blood gas and blood chemistryanalysis may show metabolic acidosis
http://www.nlm.nih.gov/medlineplus/ency/article/003474.htmhttp://www.nlm.nih.gov/medlineplus/ency/article/003611.htmhttp://www.nlm.nih.gov/medlineplus/ency/article/003484.htmhttp://www.nlm.nih.gov/medlineplus/ency/article/003468.htmhttp://www.nlm.nih.gov/medlineplus/ency/article/003468.htmhttp://www.nlm.nih.gov/medlineplus/ency/article/003484.htmhttp://www.nlm.nih.gov/medlineplus/ency/article/003611.htmhttp://www.nlm.nih.gov/medlineplus/ency/article/003474.htm -
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Radiological investigations
Abdominal ultrasounds
Abdominal CT scan
Abdominal MRI scan
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Management:-
1. prevention.
Treatment:-
1. Renal replacement therapy.
2. Monitor serum electrolyte level.
3. Control hemodynamic condition.
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Nursing Diagnosis:-
Activity Intolerance.
Fluid Volume Excess & electrolyteimbalance
Self esteem disturbance.
Knowledge Deficit.
Altered nutrition less than bodyrequirement.
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Diet.
Activity.
Care of the vascular access.
Personal Hygiene.
Follow up.
Psychological Care.
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An optimum dietary program is
important for patients onRenal failure.
The diet usually involves some
adjustment or restriction of :-
Protein , Sodium , Potassium or fluidintake.
Diet
Increase CHO in diet
A ti it
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Activity:-
The nurse should inform patient about:-
Importance of exercise.
Type of exercise, ( flexibility ex.,
strengthening ex., aerobic or
endurance ex.)
Frequency & duration of Ex.
When exercise must be stopped.
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Preparation for of the vascular access.
Personal Hygiene.
Psychological&
spiritual care Care.
C li i
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Complications
-End- stage renal diseasePericarditis
Cardiac tamponade
Congestive he0art failure
Hypertension
Platelet dysfunctionLoss of blood from the gastrointestinal tract
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Ulcers
Hemorrhage
Anemia
Hepatitis B, Hepatitis C, liver failure
Decreased functioning of white blood cells
Decreased immune response
of infection Increased incidence
Peripheral neuropathy
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Seizures
Encephalopathy, nerve damage, dementia
Weakening of the bones
FracturesJoint disorders
metabolism Changes in glucose
abnormalities including Electrolyte
hyperkalemia
http://www.nlm.nih.gov/medlineplus/ency/article/003200.htmhttp://www.nlm.nih.gov/medlineplus/ency/article/000739.htmhttp://www.nlm.nih.gov/medlineplus/ency/article/000001.htmhttp://www.nlm.nih.gov/medlineplus/ency/article/002257.htmhttp://www.nlm.nih.gov/medlineplus/ency/article/002350.htmhttp://www.nlm.nih.gov/medlineplus/ency/article/001179.htmhttp://www.nlm.nih.gov/medlineplus/ency/article/001179.htmhttp://www.nlm.nih.gov/medlineplus/ency/article/002350.htmhttp://www.nlm.nih.gov/medlineplus/ency/article/002257.htmhttp://www.nlm.nih.gov/medlineplus/ency/article/000001.htmhttp://www.nlm.nih.gov/medlineplus/ency/article/000739.htmhttp://www.nlm.nih.gov/medlineplus/ency/article/003200.htm -
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Miscarriage, menstrual irregularities,
infertility
Decreased libido,impotence
Skin dryness, itching/scratching with
resultant skin infection .
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