Renal TumorA-Primary renal tumors :

1 -Parenchymal Tumors: -Benign

Adenomas,Angiomyolipomas , Oncocytoma,,…

- Malignant: Nephroblastoma(Wilms' Tumor).

Adenocarcinoma.

0.

Renal Tumor

2-Urethelial tumors:Transitional cell cancer of renal pelvis&ueter.

B-Secondary Tumors: 1ry sites in lung,breast,lymphomas .

Renal Tumors

Wilm‘s Tumor: -common solid renal tumor of

childhood.- Age : 3 yrs. -sex : 1:1 .

- 5% bilateral.- Familial and non Familial

-associated with congenital genitourinary abnormalities.

Renal Tumors Clinical presentation:

Symptoms&Signs- Asymptomatic mass discovered by family

member or physician during routine physical examination.

- Abdominal pain,distention,anorexia,nausea, vomiting,fever,hematuria,hypertension.

Renal Tumors

Laboratory: -Urinalysis. - Anemia .

- Abnormal Liver function tests. X-RAY:

-U.S.- I.V.P.

- Chest-x-ray.- C.T.Abdomen. Needle biopsy:

Wilm‘s Tumors

Pathology: Favorable: Unfavorable:

Treatment:

- Chemotherapy: in all stages.- Radiotherapy: in all stages except stage 1.

&stage II F.H ..

Adenocarcinoma of the kidney Called also Hypernephrom,Renal cell carcinoma. most common renal tumor in adult. Age:5th-6th decade. sex: male:female 2:1.

Cell of origin:Proximal convoluted tubules. Etiology: -Cigarette smoking. (well documented) -shoes worker.,leather tanners,cadmium. -Hereditary,sporadic. -Acquired cystic disease in renal failure patients.

Adenocarcinoma of the kidney Pathology:

-Grossly:yellow to orange.- Histologically,RCC mixed adenocarcinoma

contain clear cells,granular cells ,and sarcomatoid appearing cells.

Metastasis: Direct invasion into renal vein,perinephric fat,

and adjacent viscera. Distant Metastasis to lung, liver,bone,LNS.

Robson Staging: