reporting on scientific journal articles jeremy moore, m.a. senior manager, science communications...
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Reporting on Scientific Journal Articles
Jeremy Moore, M.A.Senior Manager, Science CommunicationsAmerican Association for Cancer Research
Why is Cancer Newsworthy?
Why is Cancer Newsworthy?
• Number 1 cause of death, surpassing heart disease in 2010
Why is Cancer Newsworthy?
• Number 1 cause of death, surpassing heart disease in 2010
• In the United States, it affects one in three women and one in two men
Why is Cancer Newsworthy?
• Number 1 cause of death, surpassing heart disease in 2010
• In the United States, it affects one in three women and one in two men
• Consequences both biological and psychological
Why is Cancer Newsworthy?
• Money
Why is Cancer Newsworthy?
• Money• Government Money
– NCI Budget, 2009: $4.96 billion– NCI Budget, 2010: $5.1 billion
Why is Cancer Newsworthy?
• Money• Government Money
– NCI Budget, 2009: $4.96 billion– NCI Budget, 2010: $5.1 billion
Budget Request for 2011
$5.26 Billion
Why is Cancer Newsworthy?
• Money• Private Money
Why is Cancer Newsworthy?
• Money• Private Money• Corporate and Philanthropic
Scientific Inquiry
“In fact I have not failed 1,000 times.
I have successfully discovered 1,000 ways not to make a light
bulb.”--Thomas Edison
Scientific Inquiry
• Cancer
Scientific Inquiry
• Cancer• Out of control cell growth
Scientific Inquiry
• Cancer• Out of control cell growth• More than 200 diseases
Cancer
CURE?
Cancer
CUREvs.
CONTROL
Cancer: The Scientific Questions
• Diagnosis
Diagnosis
• Bladder Cancer• Pancreatic Cancer• Ovarian Cancer
• Breast Cancer• Colon Cancer• Skin Cancer
Cancer: The Scientific Questions
• Diagnosis• Screening
Screening
• Questions surrounding PSA, Mammography, Colonoscopy
Sensitivity vs. Specificity
Sensitivity• Correctly Identifying
Who Is Sick
Specificity• Correctly Identifying
Who Is Not Sick
MicroRNA
“The discovery of MicroRNA can be equated with the idea that we’ve known for years
that cars existed and only recently discovered they have a transmission. It’s
that fundamental.”Philip Sharp, Ph.D., Nobel Laureate from
M.I.T.
MicroRNA News from Annual Meeting 2010
• miR-21 and miR-106a are associated with an overall poor prognosis and that overexpressions of miR-181b and miR-203 are associated with poor outcomes in blacks for colorectal cancer
• MicroRNA-31 (miR-31) repressed specific tumor suppressors and, therefore, may be a novel pharmacologic target for lung cancer therapy and chemoprevention.
MicroRNA News from Annual Meeting 2010
• High levels of miR-21 were significantly correlated with poor response to Herceptin.
DNA Methylation Levels
Cancer: The Scientific Questions
• Diagnosis• Screening• Personalized Medicine
Personalized Medicine
Cancer: The Scientific Questions
• Diagnosis• Screening• Personalized Medicine• Prevention
Prevention
“At least half of all cancer deaths are preventable by what we already know
about healthy eating, exercise, maintaining appropriate weight, avoiding
smoking and going for regular screenings.” Ernest T. Hawk, M.D., M.P.H.
Vice President of the Division of Cancer Prevention and Population Sciences at The University of Texas M. D. Anderson Cancer
Center.
Prevention
• Healthy Living
Prevention
• Healthy Living• Chemoprevention
Prevention
Scientific Inquiry
75 Clinical Trials&
11 Systematic ReviewsAre Being Published Every Single Day
Bastian H, Glaszio P, Chalmers I, et al. (2010). Seventy-Five Trials and Eleven Systematic Reviews a Day: How Will We Ever Keep Up? PLOS Med 7 (9): e1000326. doi:10.1371/journal.pmed.1000326.
Journals to Watch
• New England Journal of Medicine
Journals to Watch
• New England Journal of Medicine• Journal of the American Medical
Association
Journals to Watch
• New England Journal of Medicine• Journal of the American Medical
Association• Cancer
Journals to Watch
• New England Journal of Medicine• Journal of the American Medical
Association• Cancer• Journal of Clinical Oncology
Journals to Watch
• Cancer Research
Journals to Watch
• Cancer Research• Clinical Cancer Research
Journals to Watch
• Cancer Research• Clinical Cancer Research• Cancer Epidemiology, Biomarkers &
Prevention
Journals to Watch
• Cancer Research• Clinical Cancer Research• Cancer Epidemiology, Biomarkers &
Prevention• Cancer Prevention Research
Journals to Watch
• Cancer Research• Clinical Cancer Research• Cancer Epidemiology, Biomarkers &
Prevention• Cancer Prevention Research• Molecular Cancer Research• Molecular Cancer Therapeutics
NEWS FLASH
•CANCER DISCOVERY
NEWS FLASH
•CANCER DISCOVERY– Officially announcing next week
NEWS FLASH
•CANCER DISCOVERY– Officially announcing next week– Editors in Chief, Jose Baselga, M.D, Ph.D. and
Lewis Cantley, Ph.D.
NEWS FLASH
•CANCER DISCOVERY– Officially announcing next week– Editors in Chief, Jose Baselga, M.D., Ph.D., and
Lewis Cantley, Ph.D.– Will be the premier venue for the publication
and broad dissemination of high impact research in all areas of cancer research
NEWS FLASH
•CANCER DISCOVERY– Officially announcing next week– Editors in Chief, Jose Baselga, M.D., Ph.D., and
Lewis Cantley, Ph.D.– Will be the premier venue for the publication
and broad dissemination of high-impact research in all areas of cancer research.
– First papers will be published online April 2011
NEWS FLASH
•CANCER DISCOVERY– Officially announcing next week– Editors in Chief, Jose Baselga, M.D., Ph.D., and
Lewis Cantley, Ph.D.– Will be the premier venue for the publication
and broad dissemination of high-impact research in all areas of cancer research
– First papers will be published online April 2011– In Print July 2011
THE ANATOMY OF AN ABSTRACT
• Conclusions, not titles
THE ANATOMY OF AN ABSTRACT
• Conclusions, not titles• Goals
THE ANATOMY OF AN ABSTRACT
• Conclusions, not titles• Goals• Population Samples
THE ANATOMY OF AN ABSTRACT
• Statistics– P Values, anything less than .05 is significant
THE ANATOMY OF AN ABSTRACT
• Statistics– P Values, anything less than .05 is significant– Hazard Ratios– HR=1.23, 95% CI, 1.05-1.10
THE ANATOMY OF AN ABSTRACT
FOLLOW THE NEWS
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FOLLOW THE NEWS
• Subscribe to Newswise• Check Eurekalert• Find a PR Person you trust
KEEP IN TOUCH
Jeremy MooreSenior Manager, Science Communications
Office: 267-646-0557Cell: 609-519-0212
THANK YOU