reproductive system physiology

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  • 1. Reproductive system physiology
    By
    Khorrami Ph.D.
    http://khorrami1962.spaces.live.com
    [email protected]

2. Reproductive endocrinology
Chromosome & genetic determinants, related abnormalities & syndromes.
Enzymes that influence steroidogenesis.
Brain, male type & female-type brain. sex and gender
Puberty; theories & mechanisms involved
Male reproductive organ, testis, spermatogenesis
Female reproductive organ.
Menstrual cycle; Ovulation, premenstrual syndrome ,follicle, hirsutism
Fertilization; theories, decapacitation and capacitation.
Placenta; hormonal action
Physiologic changes during pregnancy
Physiologic changes during pregnancy, endocrine disorders during pregnancy
Parturition; pain, endocrinology of parturition
Lactation; physiological functions of prolactin
Menopause/ andropause
Steroid hormones
Growth factors
Important hormones in reproductive system, prostaglandins, thromboxanes & leukotrienes & reproductive system
Physiological actions of prostaglandins, pathological & their therapeutically usage
Stem cell, cloning & related articles
3. 4. Sexual reproduction
Since 1 billion years ago
Most important factor in developmentof life
5. Stages in sexual development
Genetic
Gonadal sex
Phenotypic sex
Neuronal sex
Gender identity
6. Cytogenetic techniques
Q-bands: identification of Y & 21, 22
Quinacrinehcl
UV
G-bands: identification of all chromosomes
Giemsa
Based on bands in homologous chromosomes
C-bands: reflect constitutive heterochromatin
Repetitive DNA without specified message
Alkaline denaturation
Interstitial location in Y
Determine the origin of fault
7. 8. 9. 10. 11. Chromosomal faults
Mosaism
Chimerism
12. 13. 14. 15. 16. Genital differentiationJost(1953-1973)on rabbit
Castrated fetuses at different stages then continue the pregnancy
Castration of male
Int. & ext. genitalia ->female
Castration of female
No appreciable effect/ normal female genitalia

  • Presence of ovary is not essential for development of fallopian tube & uterus

17. Female is default sex in human