request authorization to establish genetic engineering and … · 2016-04-07 · among diverse...
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Request for Authorization to Establish the Genetic Engineering and Society
Center (CGES)
Jennifer Kuzma and Fred Gould
a. Relationship of the Center/Institute (CI) to the Mission of NC State.
We request authorization to establish the Genetic Engineering and Society Center
(CGES)1 at NC State. The GES Center builds upon NC State’s existing National Science
Foundation (NSF) Interdisciplinary Graduate Education, Research and Training
(IGERT) grant on “Genetic Engineering and Society: The Case of Transgenic Pests”
(GPM‐IGERT) and the Chancellor’s Faculty Excellence Program Cluster in Genetic
Engineering and Society (CFEP GES). The GPM‐IGERT has brought together a group of
diverse, multi‐disciplinary faculty from CALS, CHASS, CNR and COS in the planning
and delivery of its curriculum. This faculty has developed a graduate minor in Genetic
Engineering and Society that is broader than the IGERT program itself, and was
approved by The Graduate School in April, 2014.
These current programs are important. The deployment of genetically engineered (GE)
organisms into society is contentious, however, there is a need to move beyond
graduate education toward broader engagement with the community. Particularly, a
university center can serve as a trusted space for open dialogue and balanced analyses.
The GES Center will serve as a home for engaged scholarship. This approach to scholarly
work brings the activities of academe to bear on the needs of external communities and
in turn informs scholarly work with the experiences of communities. The Center will
embrace this approach, including translational research to bridge natural and social
sciences and dialogue‐based engagement beyond campus to improve understanding
among diverse stakeholders.
The idea of a GES Center fits well with the university’s land grant mission to serve the
state, its people, the nation and the world. The GES Center will take the lead in using
in‐depth research and dialogue‐based approaches to provide the public with rigorous,
trustworthy analyses of how products of GE technologies may impact society and the
environment. The proposed Center will foster innovative research, education, and
1 To find a list of all acronyms and their meanings, go to Appendix 6 at the end of this document
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engagement while acting to connect the university with local and global communities.
The GES Center will be a research center, yet tightly coupled with providing public
service and education.
Mission of the GES Center
The GES Center represents a unique example of engaged scholarship and serves as a
regional, national and international hub of interdisciplinary research and analysis and
inclusive dialogue surrounding opportunities and challenges associated with genetic
engineering and society. It is distinctive in the nation and world in its blending of
approaches from the natural sciences, social sciences and humanities to study the
intersections of genetic engineering and society. The GES Center provides mechanisms
for discussion and rigorous, trustworthy analyses about how products of genetic
engineering and synthetic biology come to be and how they may impact society. The
Center serves to improve relationships and learning across disciplines, experts and
stakeholders in order to better inform the future(s) of GE research, development and
governance. A multi‐disciplinary team of faculty engages with the Center.
Goals and Objectives
Society is at a “tipping point” in the GE arena that results from a confluence of the
power of novel technologies for genome editing, sequencing, and engineering and
rising social and ethical concerns about how technology is changing and could change
our lives, relationships and the planet. There is a need for more independent work (i.e.,
outside of industry, government and non‐government organizations (NGOs)) that
engages multiple disciplines and perspectives and is tied to community and
stakeholder needs. GES Center programs have made and are poised to continue
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making NC State a national and international leader in scholarship in this important
area. The Center fills an important gap, as it is the first of its kind to take an integrated
approach to studying the technical and societal dimensions associated with genetically
engineered organisms, synthetic biology and other advanced biotechnology
technologies.
The objectives of the GES Center are rooted in four primary activities:
1) Engagement
• Promote dialogue across colleges and other university units to improve
trans‐, inter‐ and multi‐disciplinary scholarship
• Convene dialogue and issue mapping activities for stakeholders and
citizens coming from diverse perspectives and institutions (government,
industry, academia, NGOs)
• Provide research on types and modes of engagement
2) Synthesis and communication
• Translate existing scientific information in a balanced manner (e.g., risk
studies, public perception studies)
• Document dynamics of debates and controversies
• Provide natural and social science research needed to fill knowledge gaps
3) Meta‐analysis
• Add value to existing social science, policy, humanities, natural science
and engineering data to inform decision making and programs
• Provide broader systems analysis (socio‐ecological‐technological systems‐‐
SETS) to understand behavior of systems for development, use, and
deployment of genetically engineered organisms (GEOs).
4) Decision Tools
• Create system maps for models for choices and outcomes
• Provide analytical tools, such as decision tools and develop processes for
analyzing options.
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Key long‐term practical
goals include (i) fostering
relationships among
diverse experts,
stakeholders, and citizens,
(ii) promoting bi‐
directional, social learning
about issues, opportunities,
and challenges associated
with genetic engineering
and society, and (iii)
informing and improving the future(s) of GE research, development and governance.
Supported Research
The core CFEP GES faculty engage in research either supported or hosted by the Center.
Example projects are listed below:
Genetic and ecological research on genetic pest management. (Fred Gould, Alun
Lloyd)
Innovation analysis in GE and the development of a GE patent database (Zach
Brown, GES cluster faculty)
Researchers’ attitudes and visions of GE trees for biofuels (Jason Delborne, GES
cluster faculty and Louie Rivers, CNR faculty)
Governance of synthetic biology (Jennifer Kuzma, this research project is funded
by a Sloan Foundation grant in the amount of $173,000)
Other research supported by the GES Center include the resident faculty fellow
program, visiting scholars and the history project. All of these initiatives will be
highlighted in detail in section f.
Extension and Engagement Activities
The Center participated and facilitated several engagement and outreach activities.
Faculty, students and staff participated in many venues across the state, nation and
world to engage audiences in genetic engineering and society. For a complete listing of
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outreach talks and presentations, please see Appendices 4 & 5 below entitled
“Presentations” and “GES in the Media.” Large GES Center sponsored events will be
discussed in detail in section h. In addition, three key outreach activities are
highlighted below.
Grade School Teacher Internship with the Center through a Partnership with the
Kenan Institute
In the summer of 2014, the Center welcomed Kelly Sears, a Kenan Fellow and eighth
grade teacher at Smith Middle School in Chapel Hill. She spent her time with the GES
Center split between Dr. Fred Gould’s lab working on DNA extraction/manipulation
and with Dr. Jennifer Kuzma who was leading work on the Sloan Grant for Synthetic
Biology. Ms. Sears had the opportunity to experience different aspects of the Center’s
work from each mentor. Dr. Gould’s group taught her what it was like to work in a
research lab and collaborate with other researchers, and Dr. Kuzma’s group provided
an introduction to the social sciences side of genetic engineering, working with focus
groups on new biotechnology topics. Ms. Sears took the lessons she learned to her
classroom at Smith Middle School. When asked about her experience, Ms. Sears
commented:
“the time I had with the GES Center during my externship has
transformed the way I teach evolution and biotechnology. In the past, I
rushed through biotechnology because I lacked the knowledge base to
comfortably teach the topic. I would hit the topic with one day of notes
and move on. This year, I have nestled biotechnology into artificial
selection and a unit, covering microbiology and disease. Thanks to each
of you, my students are having inquiry based lab experiences and rich
discussions about exciting topics in bioengineering that are embedded
and connected to many other areas of science.”
Ms. Sears produced videos documenting her time at the Center as well as how her
students responded to the new information. The experience will greatly increase her
outreach in the area of GE.
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Tomorrow’s Table Talk Facilitation with Orientation Classes for Different Colleges
The Center partnered with the libraries, CALS, COS and CHASS to facilitate
conversations in all of the sections of their orientation classes about the common core
reading requirement, Tomorrow’s Table by Dr. Pamela Ronald and Raoul Adamchak.
The Center had already partnered with the NC State Library to host a public talk with
the speakers and interview them for the archive as a part of the GES Center’s History
Project. By facilitating the talks in orientation classes, GPM‐IGERT students had the
opportunity to teach undergraduates, and the undergraduates received additional
insight into issues surrounding genetically engineered and organic foods.
Communications & Public Tools
In April 2014, the Center launched a website (go.ncsu.edu/ges), a social media presence
on Facebook (https://www.facebook.com/pages/GES‐Center/230025087191089),
Twitter (@GESCenterNCSU) and Tumbler
(https://www.tumblr.com/blog/ncsugeneticengineeringsociety) and created internal,
local, national and international listservs that include industry, NGOs, government,
universities, individual scientists and other interested stakeholders. The Center’s
website provides information about its research, upcoming and past events, its partners,
projects and publications and covers media exposure that the Center has received. The
website is equipped with various tools that enable the public at large to learn more
about GE, GES and policies surrounding GE. The website provides definitions of
common GE terms, demonstrates the evolution of genetic/biotech approaches and a
timeline of the history of GE. In May 2015, the GES Center launched is inaugural
monthly newsletter.
Honors and Awards
In the first year of Center operations many associated faculty and students have
received honors and awards.
Dr. Jennifer Kuzma, the center’s Co‐Director and Goodnight‐NC GSK Foundation
Distinguished Professor in the Social Sciences was awarded honors as the 2014 Society
for Risk Analysis Sigma Xi Distinguished Lecturer Award for Outstanding
Contributions to the Field of Risk Analysis and she was elected Secretary and Council
Member for the Society for Risk Analysis (2014‐present).
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Dr. Fred Gould, GES Center Co‐Director and William Neal Reynolds Professor of
Agriculture was honored with the Founders Memorial Award from Entomological
Society of America. He was also selected to become the Chair of the National Academy
of Sciences study on ʺGenetically Engineered Crops: Past Experiences and Future
Prospects.ʺ
b.RelationshiptoorPotentialImpactUpontheExistingDepartments,Collegesand/orSchools,andotherCentersandInstitutesintheUNCSystem.The challenges associated with GES are complex and fit the definition of “wicked
problems”, with interdependencies that are difficult to predict or characterize. No single
authority, discipline, or perspective can address sufficiently the challenges alone. The
center will facilitate interactions across traditional boundaries that will catalyze
innovations in how these challenges are addressed.
To our knowledge, similar units do not exist in the UNC system that focus specifically on
all aspects of GE and their nexus with society. Duke University’s Science and Society
program is involved in bioethics and genomics, but does not focus on GE for agricultural
and environmental applications. The leadership of the GES Center has established
contact with Duke’s Institute for Genome Sciences and Policy (IGSP) faculty and its
former director, Robert Cook‐Deegan who was involved in the NC State‐IGERT on GES.
The Center and IGSP are currently advertising each other’s events on their listervs and
websites, and the Center hopes to expand the partnership with IGSP as well as partner
with other units within the UNC system.
The GES Center engages students, faculty, and staff from at least twenty departments in
four NC State colleges. The Center plans to closely cooperate with the Synthetic and
Systems Biology cluster at NC State. Jennifer Kuzma gave a talk at the center for
Economic and Environmental Policy in CALS as a starting point for this collaboration.
The Center plans to cooperate closely with the Synthetic and Systems Biology cluster at
NC State as well as Science, Technology and Society (STS) program. The Center has
already partnered with the STS program along with the Genetics program and the Keck
Behavioral and Biology Center to host the Intersections of Genetics and Society
symposium held on September 19, 2014 (see section h). To spark conversation about
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contemporary GEO issues and opportunities in the broader NC State community and the
public, in fall 2014 the Center partnered with the Science and Technology Studies (STS)
Program to use film to start conversations with broader audiences. In spring 2015, the
Center hosted two documentary series events: one on patenting of GE seeds (Percy
Schmeiser: David vs. Monsanto) and the other on bringing back extinct species with
synthetic biology techniques (The Hunt for Life). The Center hosted screenings followed
by panel discussions, and both events were well attended. Professors Kathleen Vogel
(STS) and Zachary Brown (CFEP GES faculty) are leading the Center’s documentary
series which will continue fall 2015.
The Center co‐directors have met with key GE faculty from UNC‐Chapel Hill (Maryann
Feldman) and Duke Science and Society (Jonathan Weiner, Arti Rai) and discussed the
possibilities of future collaborations.
The GES Center also hosted the First Annual GE @ NC State Symposium which brought
faculty from different departments all over campus who work on genetic engineering to
come together to discuss ways in which they could collaborate. This symposium is
discussed in more depth in section f.
c.TheNameoftheProposedDirector(s)andaDetailedDescriptionofanyProposedAdvisoryCommitteesorDirectiveBoards.The co‐directors of the Center are Professors Fred Gould (Entomology/CALS) and
Jennifer Kuzma (School of Public and International Affairs/CHASS). They provide
linkages between the GPM‐IGERT and the Center.
Faculty in CHASS, CALS, CNR, and COS will be actively involved in GES Center
operations. The Responsible Administrator will be the Vice Chancellor for Research,
Innovation and Economic Development (ORIED).
An Internal Advisory Committee (IAC) will consist of the Deans, or their designees,
from CALS, CHASS, CNR and COS and representatives from the Office of the Provost,
and ORIED. The IAC will provide guidance on ongoing projects and activities, as well
as for long term strategic planning, and will meet at least twice during each academic
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year. The IAC initially met on May 6th, 2014 and provided input on strategic directions
for the Center. They met again on January 8th, 2015.
An External Advisory Committee (EAC) consisting of representatives of stakeholders
from industry, government, NGOs and other academic institutions will help guide
strategic planning and fundraising for the Center and will meet at least once per
calendar year. The first meeting of the EAC was held January 8 – 9, 2015. This was an
in‐person meeting, but some future meetings will be held via Skype. Shortly after the
meeting, EAC members were put in sub‐groups to advise the Center about specific
topics, such as communications and fundraising. During of summer 2015, the GES
Center met with all of the subgroups through conference calls to get advice on five key
elements of the Center: communications, academic scholarship, collaborations with
government and industry, public engagement and fundraising. A table listing the
members of the EAC is included as Appendix 3.
The Center’s Executive Committee (EC) meets on a regular basis to plan activities,
events and research. The EC consists of the following members: the Center’s co‐
directors; Dr. Jason Delborne, Associate Professor of Science, Policy and Society; and Dr.
Zachary Brown, Assistant Professor in Agricultural and Resource Economics. In
addition to the EC, several other faculty form varying departments are affiliated with
the Center by partnering in research, events and activities. A list of these faculty is
included in Appendix 2.
FundingThe budget template attached to this request to establish includes estimated
expenditures and funding sources for the 5 year period from July 1, 2014 through June
30, 2019. As detailed in Appendix 7, annual support in the total amount of $280K for 5
years was secured from the Vice Chancellor for Research, Innovation and Economic
Development (ORIED) ($50,000), Office of the Provost ($50,000), CALS ($50,000),
CHASS ($50,000), CNR ($50,000) and COS ($30,000). Most of this money comes from
Facilities and Administrative (F&A) funds, but it also comes from foundation and state
appropriated funds as well. Additionally, in fiscal year 2014 ‐ 2015 the GES Center co–
directors received a $598,845 installment from GPM‐IGERT grant, a $25,000 installment
from the Alfred P. Sloan Foundation and a grant from USDA to cover most of the
expenses for the USDA Co‐existence Workshop in the amount of $31,792. The Center
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also received donations from the University of Michigan for $5000 to help support the
iGEM team, $2000 from Multi‐Site Public Engagement with Science – Synthetic Biology
for outreach about GE with museums and $15,000 from the Kenan Institute at NC State
to support conferences on GE. In the summer of 2015, the GES Center received word
from NSF that a gene drive grant proposal for $50,000 and a proposal to compare
cultures of responsible innovation across bioengineering communities for $350,000
would be funded. More information about these grants can be seen in the table entitled,
“Proposals and Awards Submitted through the GES Center” below.
GES cluster faculty and co‐directors are housed in various colleges and departments:
Co‐director Jennifer Kuzma is in the School of Public and International Affairs (SPIA) in
the College of Humanities and Social Sciences (CHASS); Co‐director Fred Gould is in
the Entomology Department in the College of Agricultural and Life Sciences (CALS);
Cluster faculty member Dr. Jason Delborne is in the Department of Forest and
Environmental Resources (FER) in Natural Resources (NR); and Dr. Zach Brown,
another cluster faculty, works in the Agricultural and Resource Economics and
Entomology in CALS. Departments provide in‐kind support with space, general office
equipment, and supplies.
PersonnelCostsThe Center has two co‐directors, and their base 9‐month salaries are not a part of the
overall Center budget because they are both full‐time faculty members and their 9‐
month salaries are paid by their departments. Part of their summer salaries are a part
of the Center budget, and part of their summer salaries are paid from other sources.
Other positions such as research assistants or subcontract affiliates will be funded by
contracts/grants/task orders and are not listed here. Although the IGERT coordinator is
included in the Center’s budget as a part of the GPM‐IGERT award, her position is not
covered here because it will end when the IGERT grant ends in FY 2015‐2016.
Center Deputy Director ‐ This is a 12‐month, full‐time EPA professional position,
beginning in year 1, to manage day‐to‐day operations of the Center, oversee the budget,
create marketing collateral and oversee communications, organize events, facilitate
outreach, supervise employees and troubleshoot problems.
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Program Assistant ‐ This is a 12‐month, full‐time SPA position beginning in year one to
support the Center and one of the co‐directors, process all financial transactions,
organize events and work on day‐to‐day operations of the Center.
Student Communications Assistant – This is a part‐time temporary position that was filled
in October 2014. This position assists in creating advertising collateral, growing social
media presence, updating website, producing a monthly newsletter and filming various
events.
Other Expenditures
• Resident Fellow Research. The center will fund each faculty resident fellow up
to $20,000 per year for their Center‐related research. The number of Research
Fellows that the Center supports will vary from year to year.
• History Project
• IGERT Teaching. This would include summer salaries for faculty members who
travel to various international locations to teach the course for the IGERT
students
Stipends for IGERT students to do their research
• iGEM Team in Policy and Practice (expenses related to participation in iGEM
Jamboree).
• Travel for GES Students and Faculty to present research
• Intersections of Genetics and Society Symposium
• Partial sponsoring of Arizona State University Conference at which both GES
faculty and students presented. Co‐director Jennifer Kuzma is on the Executive
Committee of this conference.
• GES Patent Project
• GES Biofuel Scientist Engagement Project
• Public Education Tools
• Annual GES Conference
Educational Materials
• Operating Costs
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Projections for Future Center Funding (see Appendix 8)
Federal grant support received by the Center will facilitate research and engagement
projects directly, and the Center will also benefit indirectly via the return of twenty‐five
percent of overhead funds associated with these proposals (per agreement with
ORIED). This is reflected in the budget template attached to this request to establish. It
also includes carry‐over from year‐to –year. The GES Executive Committee made a
prudent decision to save some money every year to help sustain core funding past 2018,
when it no longer receives funding from colleges and units at NC State. As a result of
this, the Center should have a surplus of over 1.5 million dollars in 2019.
In its first year of operations, cluster faculty associated with the Center submitted grant
proposals totaling over $8 million. Three of these proposals were submitted through
the Center (totaling $988,911), and three additional proposals were submitted outside
the Center. These latter proposals are anticipated to provide partial support for Center
operations should they be funded (please see Proposals Submitted Chart below).
Additionally, the Center was recently notified that it will receive $50,000 from NSF to
support a workshop on gene drives as well as an NSF grant to look at responsible
innovation in emerging technologies for $350,000. Budget projections for FY 2015‐ 2019
that appear on the budget template include pending proposals routed through the
Center. For proposals submitted by Center‐associated faculty that were not routed
through the Center, only the fraction of each proposal that is expected to benefit the
Center is included in projected funding levels.
In addition to the submitted proposals included in budget projections, the Center is
developing a project that focuses on the views of youth on the next generation of
genetic engineering. This project has garnered attention from a wide variety of
stakeholders and will be the basis for a funding proposal by 2018. The Center has
developed relationships with many partners in its first year of operations, e.g. the James
Beard Foundation, the SynBio Project at the Woodrow Wilson Center, the NC
Biotechnology Center, the Bill and Melinda Gates Foundation, the Long Now
Foundation, NC Center of Innovation Network (COIN), and others. The co‐directors
have and will pursue these organizations for funding to support core operations of the
Center. The Center is involved in discussions with the NC Biotechnology Center about
possible research partnerships, and also seeks private benefactors and small
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contributions from a variety of unconventional sources, such as Kickstarter.com, for
specific projects. The Center has also partnered with the CHASS development team to
help raise core funding. Finally, the Center is considering the development of a business
model that includes training courses for nutritionists, teachers and other professionals.
Proposals and Awards Submitted Through the GES Center (Data Extracted from
RADAR)
Project ID
Title Investigator(s) PI Department
Sponsor Status Amount Proposed or Awarded
Proposed or awarded Period of Performance
(1504) 2016-0363
COLLABORATIVE RESEARCH: Efficacy of Participatory Technology Assessment Forums for Public and Policy Engagement in Synthetic Biology
Delborne, Jason Aaron Kuzma, Jennifer
Forestry and Environmental Resources
National Science Foundation (NSF)
Proposed $50,902 12/01/2015-11/30/206
(0619) 2016-0359
Archiving Agricultural Genetic Engineering and Society (AAGES)
Wynn, Alison Booker, Matthew MorseKuzma, Jennifer Brown, M.J. Eleanor
Center on Genetic Engineering and Society (GES)
National Science Foundation (NSF)
Proposed
$488,916
01/01/2016-12/31/2018
(0619) 2016-0021
Archiving Agricultural Genetic Engineering and Society (AAGES)
Wynn, Alison Booker, Matthew MorseKuzma, Jennifer
Center on Genetic Engineering and Society (GES)
National Science Foundation (NSF)
Proposed $456,683 07/01/2015-06/30/2017
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Brown, M.J. Eleanor
(0619) 2015-2228
USDA Stakeholder Workshop on Coexistence of Genetically Engineered and Conventional Crops
Gould, Fred L. Kuzma, Jennifer Delborne, Jason Aaron
Center on Genetic Engineering and Society (GES)
Animal and Plant Health Inspection Service (APHIS) - USDA
Awarded $31,792.00
03/09/2015- 06/30/2015
(0619) 2015-2099
Comparing Cultures of Responsible Innovation Across Bioengineering Communities
Kuzma, Jennifer Banks, Erin Berube, David M. Gould, Fred L. Herkert, Joseph R.
Center on Genetic Engineering and Society (GES)
National Science Foundation (NSF)
Proposed $350,000 01/01/2016-12/31/2017
(0619) 2015-1789
Gene Drives: A Deliberative Workshop to Develop Frameworks for Research and Governance February 24-26, 2016
Kuzma, Jennifer Gould, Fred L.
Center on Genetic Engineering and Society (GES)
National Science Foundation (NSF)
Awarded $50,000
08/01/2015 -07/31/2016
(1504) 2015-1741
Collaborative Research:Moral Fiber: Genetically Modified Trees, Responsible Innovation, and Environmental Justice
Delborne, Jason Aaron Rivers, Louie
Forestry and Environmental Resources
National Science Foundation (NSF)
Non-Funded
$369,280
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(1722) 2015-1675
A Genetic Engineering Approach to Rodent Pest Management
Godwin, John R. McGraw, Lisa Anne Gross, Kevin R.Gould, Fred L. Haddad, Nicholas M. Lloyd, Alun L. Reiskind, Martha Burford
Biological Sciences
NCSU Research and Innovation Seed Funding Program
Awarded $14,929 01/01/2015 -12/31/2015
(0670) 2015-1239
OA2015: Integrated Model of Gene-Regulatory and Metabolic Networks to Assess the Interactive Effects of Coastal Hypoxia, Acidification and Warming on Oysters
Schaff, Jennifer Genomics Research Lab
South Carolina Department of Natural Resources (Prime--National Oceanic & Atmospheric Administration (NOAA)
Proposed $128,995 03/01/2015-02/28/2018
(1180) 2015-0188
CAREER: Faculty Research in Economics: Global Innovation in Biotechnology, Adoption Dynamics and Bioeconomic Feedbacks
Brown, Zachary Steven
Agricultural & Resource Economics
National Science Foundation (NSF)
Proposed $498,000 01/01/2015-12/31/2019
(0619) 2014-3038
CCE STEM: Facilitating Learning about Meanings of
Kuzma, Jennifer Banks, Erin Gould, Fred L.
Center on Genetic Engineering
National Science
Proposed $485,000 01/01/2015-12/31/2016
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Responsible Innovation in Bioengineering
Delborne, Jason Aaron Berube, David M.
and Society (GES)
Foundation (NSF)
Total Amount Awarded: $96,721.00
Total Amount Proposed: $2,924,497
Awards and Proposals Not Submitted Through the GES Center that Will Provide
Partial Support for the Center (Data Extracted from RADAR)
Project ID Title Investigator(s) Sponsor Status
Amount Proposed
or Awarded
Proposed or Awarded Period of
Performance
Portion of Funds
Allocated to GES Center
(1606) 2013-2801
To Use Risk Assessment Tools to Analyze Three Current Synthetic Biology Applications; Looking Forward to Synthetic Biology Governance: Convergent Research Cases to Promote Policy-Making and Dialogue
Kuzma, Jennifer
Alfred P. Sloan Foundation
Awarded $173,703
06/01/2013- 06/30/2015
100% (this proposal was funded at another university and transferred to NC State)
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(1110) 2015-2611
Improving Bt Resistance Risk Assessment and Management by Genomic Monitoring
Gould, Fred L. Fritz, Megan Lindsay
US Dept. of Agriculture (USDA) - National Institute of Food and Agriculture
Proposed $498,561 08/15/2015-08/14/2018
10%
(1110) 2013-2587
Evolutionary Consequences of Invasions of Novel Genotypes and Selfish Genetic Elements (previous title: Empirical Testing of Two-Locus Theory and Predicted Behavior of Selfish Genetic Elements)
Gould, Fred L.
University of California - Irvine (Prime--W. M. Keck Foundation)
Awarded $224,99001/01/2014- 12/31/2016
80%
(1110) 2012-1621
Genomic Approaches for Bt Resistance Risk Assessment and Improvement of Regulatory Triggers
Gould, Fred L.
US Dept. of Agriculture (USDA) - National Institute of Food and Agriculture
Awarded $499,99909/01/2012- 08/31/2015
10%
(1110) 2010-1935
IGERT: Genetic Engineering and Society: The Case of Transgenic Pests
Gould, Fred L.
Lloyd, Alun L.
Haenn, Nora
Haddad, Nicholas M.
Kinsella, William J
National Science Foundation (NSF)
Awarded $2,998,062
08/15/2011- 07/31/2016
100% (since 2013 -2014)
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(1110) 2016-0252
Sustainable spotted wing drosophila management for United States fruit crops
Burrack, Hannah
Scott, Maxwell J
Brown, Zachary Steven
US Dept. of Agriculture (USDA) - National Institute of Food and Agriculture
Proposed $7,331,95609/01/2015-08/31/2019
0.10%
Total of Projected Amount of Center Funding $ 2,259,842
Total of Actual Amount of Center Funding $2,202,532
d.SpaceandCapitalEquipmentRequirements.
Six offices, currently assigned to the Center in the Hunt Library, should be sufficient in
the first few years of the Center’s operation. The Center will need additional office
space in the future for its growing faculty and staff.
e.AStatementRegardingtheEfficacyofPlansImplementedtoAssureProperRecognitionofParticipatingJuniorFacultyWhereRelevant.Junior cluster faculty will be evaluated annually, both by their home departments and
by the GES co‐directors and will have a choice between a traditional department tenure
voting faculty or requesting an interdisciplinary set of faculty matching the areas of
research by the candidate. The co‐directors will serve as mentors and provide
opportunities for junior cluster faculty to engage in cutting‐edge interdisciplinary
research and will connect them with external supporting organizations to benefit their
research and scholarship. Even though the Center is still in its planning stage, it is
already supporting one junior cluster faculty member in his quest to document all GE‐
related patents. Senior faculty are functioning as a review panel of the proposal he is
writing to obtain seed funding for his research.
f.StatementaboutAnticipatedEffectsoftheProposedUnitontheInstructionalProgramsofNCState,andtheProvisionsforAdvancedorGraduateTrainingorDegreePrograms.As mentioned earlier, the GES Center will take the lead in using in‐depth research and
dialogue‐based approaches to provide the public with rigorous, trustworthy analyses of
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how products of GE technologies may impact society and the environment. The Center
will foster innovative research, education and engagement while acting to connect the
university with local and global communities.
Teaching
GES faculty will expand on the courses already developed for the GES graduate minor
which was approved by the Graduate School in April, 2014. In addition to the graduate
minor courses, the Center plans to develop an undergraduate course on Genetic
Engineering and Society and an online continuing education course on Genetically
Engineered Foods. The Center is also considering the creation of a GES certificate
program for both students and interested stakeholders. The courses offered in 2013 –
2014, are below.
Course Number Course Name
GES 506 Principles of Genetic Pest Management
GES 508 Emerging Technologies and Society
GES 591‐002 GES Colloquium
GES 591‐501 Pest Issues in Developing Countries
GES 591 Systems Thinking and Modeling
Of particular note is the planning and teaching of the international course GES 591‐501,
Pest Issues in Developing Countries. The NC State GPM‐ IGERT Students and GES
Faculty went to Mexico July 19 – August 9, 2014, to study GE crop and pest
management issues. This was the first academic experience of the entering 2014 GPM –
IGERT student cohort. It was held in a part of the world where students could gain
first‐hand experience in a country that provides contrast in agricultural, political and
cultural factors. Of all Latin American countries, Mexico has had the most direct
intersection between its subsistence agricultural base and the commercial development
of genetically engineered crops. The introduction of genetically modified corn was felt
keenly in a country proud of its heritage as the culture that developed hundreds of
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maize varieties. When genes from genetically engineered maize unintentionally moved
into traditional Mexican maize varieties, Mexico’s federal agents structured regulatory
committees to govern all genetically engineered organisms. These federal regulations
stand alongside common‐property institutions (ejidos) that are often home to
subsistence farmers and whose members govern access to their communities. Issues
about transgenic crops continue to be a major political issue in Mexico. In Mexico City,
the students visited with regulatory agencies, pro and anti GM crop activists, and with
university and other research personnel. They gained a sense of diverse perspectives on
transgenic crops and how those perspectives influence views on transgenic insect pests.
In Oaxaca, the students spent time in two local agricultural communities to understand
their cultures, values and views on how their farming can be improved. Students
worked on the farms and examined insect pest problems that could be addressed using
engineered pest strains.
The Center will engage IGERT and other graduate students in its research. The Center
sponsored a graduate student iGEM team for the international jamboree in November,
2014. A more detailed description of this event is in section a.
Resident Faculty Fellow Program
During the first nine months of the GES Center planning stage, we established a
Resident Fellows program to further our engagement of existing NC State faculty in the
Center (i.e., beyond three CFEP GES hires). Four faculty members were chosen and
awarded seed grants in a peer review process in order for them to conduct inter‐
disciplinary and translational research projects that are designed to have impact on GES
scholarship and practice:
Dr. Rajade Berry‐James, an Associate Professor in the School of Public and
International Affairs (SPIA), is conducting a focus group study to gain an
understanding of cultural perceptions of consuming genetically modified foods,
and exploring cultural strategies that inform underrepresented groups about
scientific advances in genetically modified (GM) food production. She and two
SPIA graduate students conducted these focus groups in 2014 with religious,
African American communities in the NC Triangle region and are currently
analyzing the data for publication.
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Dr. David Berube, Professor of Communications, is working on three projects to
explore the role that citizen scientists and citizen science advocates have on
biotechnology research and industries: 1) a project to determine the roles that
lay citizens doing biology research, or “Do‐It‐Yourself Biology” (DIYBio), will
play in regulatory actions; 2) a project researching how the international
genetically engineered machines (iGEM) competitions serve as a platform for
patent generation and corporate acquisitions of the machines; and 3) a project
looking into the relationship between the BioBricks Foundation and the
commercialization of synthetic biology.
Dr. Andrew Binder, Assistant Professor of Communications, is conducting a
project that will produce an up‐to‐date, interdisciplinary synthesis of published
research on public opinion of GE technologies. He is conducting content
analysis and bibliometric analysis on publications in the peer‐reviewed literature
that address citizen acceptance of and attitudes towards GMOs. His meta‐
analysis is comparing how the questions are asked, who the researchers are and
whether these factors influence consumer answers about GMO perceptions.
Dr. Jane Hoppin, an Associate Professor in the Department of Biological Sciences
in the College of Sciences, is researching the potential effects of GMO foods on
human health. She is conducting a formal analysis of potential exposure
pathways for both agricultural workers and consumers. Related exposures will
also be considered, such as the potential reduction in diesel exposure or
increased contact with Roundup herbicide. Dr. Hoppin and her students will
review the toxicological and epidemiological literature to contextualize these
exposure pathways.
Resident Fellows have been active in the GES community, attending events,
participating in workshops, and assisting with Center activities and planning. The
results of their research will not only be published in the peer‐reviewed literature, but
will also be developed into “Research Briefs” of the GES Center in 2015 and 2016,
for the public. Dissemination of these briefs to stakeholders and policy makers will
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increase the GES Center’s ability to inform state, national and international decisions
about genetic engineering.
The History Project
Debates about genetic engineering have not changed much over the past 25 years. With
the advent of new biotechnologies like gene editing, synthetic biology, and gene drives,
GE conversations include a new generation of scholars that are perhaps not aware of or
privy to issues, challenges, opportunities and challenges stemming back several
decades. The Center co‐directors, Dr. Kuzma and Dr. Gould, noticed at national and
international workshops and meetings on GEOs and synthetic biology, that this new
generation of experts and stakeholders do not often recognize the longer history of the
GEO debates. Furthermore, people involved in that history are ending their careers or
passing away, and society is at risk at losing this historical knowledge which can inform
and improve contemporary and future research, engagement and decision making.
To address this concern the Center launched a history project under the leadership of
Dr. Matthew Booker (GES Faculty Fellow), Associate Professor of History and Alison
Wynn, GES Center Deputy Director. They work in partnership with the NC State
Libraries and the Department of History. The mission of this project is to produce an
archive that will both inform the public at large about the history of GE and its policies
as well as serve as a roadmap for future scientists and historians who are interested in
studying the origins of GE. The project has three primary goals: 1) to promote the work
of the GES Center, engage the community by hosting public and webcast talks by
prominent historical figures in GES, and produce video clips of interviews with invited
guest speakers for the Center’s website; 2) to encourage public access to the history of
GE ideas, practice and impact by posting a full length video of these interviews on a
website; and 3) to create an archive of high‐quality oral histories by filming interviews
with key figures in the field that will become a part of the NC State Library Special
Collections. Two key figures holding different points of view about GE are invited to
speak publically each semester and participate in in‐depth interviews that will serve as
the basis for a historical archive and future research and analysis.
To ensure success, the project has partnered with other stakeholders at the University
and beyond. NC State Library Special Collections is supporting the project by providing
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a part‐time post‐doc and some funding for the GE speakers. The History Department is
supporting the project by providing a research assistant who will transcribe video of
key GE player interviews. All GES seminars are on the recommended list of required
talks for both the University Scholars Program and the Parks Scholars program. Brad
Herring, a videographer at the North Carolina Museum of Life and Sciences,
participates in the project. Along with the NC State University Library, the GES Center
co‐hosted the University’s common reading for 2014, a public talk called Genetics, Food
and Society by Tomorrow’s Table authors Dr. Pamela Ronald and Raoul Adamchak on
August 19, 2014. The participating authors of the talk have been interviewed and
filmed for the archive. Dr. Margaret Mellon from the Union of Concerned Scientists
spoke to a full room in a webcasted public talk on September 5, 2014, and filmed a
video interview for the website and the archive. Dr. Ignacio Chapela, Dr. Anthony
Shelton and Dr. David Zilberman were interviewed in spring 2015. The History Project
team applied for a National Science Foundation Science Technology and Society grant
in February, 2015 (review pending) to expand and enhance the program.
Visiting Scholars
As noted before, the Center is supporting research done by four GES faculty fellows, as
well as three projects that are being conducted by junior GES faculty. In addition, the
GES Center hosted three visiting scholars in 2014‐2015 for a semester or the academic
year to conduct research on GE related activities and participate in the Center’s
activities:
Dr. Kaiming Guan is an Associate Professor of Philosophy in the Department of
Philosophy at Wuhan University of Science and Technology. Dr. Guan received
his doctorate from Wuhan University in 2009, majoring in Philosophy of Science
and Technology. Dr. Guan’s research interests involve science and technology
studies, including the social dimensions of science and technology, science
communication, public understanding of science, and science and technology
policy and governance. During his year with the Center, he conducted an
analysis of US versus Chinese perceptions of GE foods and established
collaborations with GES faculty for the future.
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Dr. Russell Powell is an Assistant Professor in the Department of Philosophy at
Boston University. Prior to his appointment at BU, Dr. Powell was an Arts and
Humanities Research Council Fellow in the Faculty of Philosophy, and a James
Martin Research Fellow in the Institute for Science and Ethics at Oxford
University. During his semester with the Center, he embarked on research on the
ethical dimensions of gene drives and de‐extinction, and participated by
speaking in the GES Center’s Colloquium and Documentary Series.
Dr. Joseph R. Herkert is Lincoln Associate Professor of Ethics and Technology in
the School of Letters and Sciences and the Consortium for Science, Policy &
Outcomes at Arizona State University. Dr. Herkert has been teaching
engineering ethics and science, technology and society courses for more than
twenty‐five years and has published numerous articles on engineering ethics and
societal implications of technology in engineering, law, social science, and
applied ethics journals. Dr. Herkert previously served as Editor of IEEE
Technology and Society Magazine and an Associate Editor of Engineering
Studies. He was recently elected a Fellow of the American Association for the
Advancement of Science. He joined the GES Center in spring 2015, to do research
on the societal implications of GE.
iGEM Competition Winner
In November of 2014, the center sponsored a group of students to participate in the
iGEM (International Genetically Engineered Machines) competition inaugural division
of “policy and practice.” We are extremely proud to say that they won first place in this
division at the iGEM jamboree. GES Co‐director Dr. Jennifer Kuzma and Dr. David
Berube led the team that includes students from NC State Departments of Public
Administration, Science Communication, Genetics, Entomology Forestry and Environ‐
mental Resources and a student from the University of North Carolina (UNC) Public
Policy Department. To prepare for the iGEM competition, the Center partnered with
Glowing Plants, a startup company, and the Risk Science Center at the University of
Michigan to develop a decision analysis tool that explores the values behind choices
when developing GEOs. University of Michigan supported this effort by sponsoring
the team with $5000 to help offset some of the expenses of this endeavor.
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Colloquia
The Center hosts a weekly colloquium at NC State where IGERT students, affiliated
faculty, internal and external speakers and other students in the areas of natural/social
sciences and humanities share and discuss research related to the responsible
development and deployment of genetic engineering. Colloquia topics range from
those presented formally by external speakers and NC State faculty outside of the GES
Center, to less formal conversations about current events surrounding GEOs or about
the functioning of the GES Center itself. Students have also used these colloquia as
opportunities to practice their presentations for national and international meetings.
Informal conversations have included guided discussions on increasing the diversity
and improving the experiences of students in the GES Center, reactions to media
surrounding GE foods, and tutorials on gene drive technologies. Weekly attendance
averages around 30 participants.
The First Annual GE @ NC State Symposium
The GES Center hosted the First Annual GE @ NC State symposium on Tuesday, April
28, 2015. Sponsored in part by the GES Center, CALS and the Center for Comparative
Medicine and Translational Research (CCMTR), over 126 faculty, students and
administrators met to talk about GE research performed on campus and how they could
collaborate in the future to increase their multi‐ and interdisciplinary efforts. The
symposium included a full day of speaker presentations and a graduate student and
post doc poster session at the end of the day.
g.ADescriptionoftheCenter’sAdministrativeStructure,IncludinganOrganizationalChartShowingtheRelationshipoftheProposedCItotheExistingOrganizationsofNCStateandtheInternalOrganizationoftheProposedCenter.
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h.WhenRelevant,StatementsonInter‐InstitutionalNatureoftheProposedCenter,WhetheritbeMission,Leadership,Activities,FundingorotherAspects.AnyAdditionalInformationthatMayBearDirectlyUpontheProposal.The GES Center plans to continue collaborating with Arizona State University (ASU),
which has two prominent centers related to emerging technologies. Dr. Kuzma serves
on the board of visitors for the ASU Center for Nanotechnology and Society and is
serving on the Executive Committee to host an ASU‐NSF workshop to develop a
research agenda for synthetic biology. Duke’s Science and Society program is
considered as a potential partner for activities related to human health and genomics.
The Center collaborates with the Museum of Life Sciences (MLS) in Durham on the
videography of the History Project and plans to develop additional collaborations with
the Natural Sciences Museum and the History Museum, both in Raleigh, NC.
The Center has developed relationships with several international and foreign entities,
such as The United Nations Food and Agriculture Organization, The International
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Maize and Wheat Improvement Center (CIMMYT), CIBIOGEM (the Mexican GMO
regulatory agency), and the Chinese Academy of Agricultural Sciences.
National and International Workshops
GES‐CIMMYT Workshop on GEOs in Mexico
The Center partnered with the International Maize and Wheat Improvement Center
(CIMMYT) and Inter‐ministerial Commission on Biosafety of Genetically Modified
Organisms in Mexico (CIBIOGEM) —to host a symposium on GE crops on July 24, 2014
entitled, Transgenics and Society: Towards a constructive dialogue that contributes to policies
and regulatory frameworks. The event was organized to highlight the importance of
scientific and moral considerations surrounding individuals’, and hence, society’s
perspectives about transgenic crops and other emerging technologies. NC State GPM‐
IGERT students and faculty went to Mexico to study issues surrounding transgenic
crops and insects during this time for their IGERT international course. Prof. Gould,
Delborne, and Kuzma spoke at the event which included policy makers, scientists and
stakeholders from many regions in Mexico.
GES‐Keck Workshop on Genetics and Society
In partnership with NC State W.M. Keck Center for Behavioral Biology, the Genetics
Program, the Science, Technology and Society Program and the NC State Library, the
Center hosted a graduate and post‐doc workshop and a symposium on September 19,
2014. Both were entitled Intersections of Genetics and Society. Four prominent speakers
included: Dr. George Church, a Professor of Genetics at Harvard Medical School and
Director of PersonalGenomes.org, which provides the worldʹs only open‐access
information on human Genomic, Environmental and Trait data; Dr. Paul Lombardo,
Senior Advisor to the Presidential Commission for the Study of Bioethical Issues and
Professor of Law at Georgia State University College of Law; Dr. Sarah Richardson,
John L. Loeb Associate Professor of the Social Sciences at Harvard University; and Amy
Harmon, two‐time Pulitzer Prize winning science correspondent for the New York Times.
They presented their diverse perspectives on this topic and talked about their career
paths. At the workshop, NC State graduate students, including those from GPM‐
IGERT, discussed their research with attendees. NC State Provost, Warwick Arden,
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introduced the symposium which was held in the Hunt Auditorium. The symposium
was open to the public at large and was very well attended.
2nd Annual Conference on GETs
The Center co‐sponsored the 2nd Annual Conference on Governance of Emerging
Technologies (GET) in May, 2014 in Scottsdale, AZ. Center funds provided financial
support to GPM‐IGERT students Elizabeth Pitts, Amanda Clayton, Sheron King, and
Molly Storment and to Sloan Foundation research assistant Tina Ndoh who were
chosen by the GET committee to make presentations at this event. The conference was
very successful for Center networking, and all of the NC State students made a very
positive impression. Dr. Jennifer Kuzma is on the planning committee for this annual
workshop and noted that by the end of the conference, the GES Center and IGERT
program were discussed publicly by several others in this international scholarly
community, putting the Center on the map.
Gordon Conference on Science and Technology Policy
Dr. Jennifer Kuzma and Executive Committee member Dr. Jason Delborne served as
Chair and Vice Chair, respectively, of the 2014 Gordon Science and Technology Policy
Research Conference. Both were elected in 2010 and 2012 to serve in this capacity by
the science and technology policy community. Gordon Research Conferences have
been premier conferences for natural science and engineering disciplines for several
decades. Dr. Fred Gould also gave a presentation on interdisciplinary graduate
education, and GES research assistant and public affairs Ph.D. student Tina Ndoh
presented a poster. Held in August in New Hampshire, this conference proved to be a
great opportunity for the Center’s exposure, recognition and networking. Dr. Kuzma
applied for and received a $50,000 NSF grant in 2014 for this workshop.
Delphi Policy Workshop on Synthetic Biology Governance
With support of a Sloan Foundation grant (Dr. Kuzma as PI) the Center hosted an
international workshop on June 3‐4, 2014 at NC State, drawing fifty subject matter
experts in synthetic biology (SB) to discuss four case studies of SB application, potential
data and information needs, and ideal governance systems for them in the framing of
responsible innovation and anticipatory governance. The workshop was part of a
Delphi expert panel study, the first of its kind to assess future societal implications
associated with SB.
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Environmental Justice and Synthetic Biology Workshop
On October 14, 2014, the GES Center hosted a 1‐day workshop entitled Early Inclusion of
Environmental Justice Communities in Governance of Emerging Technologies‐ Synthetic
Biology Case Studies. GES Ph.D. students and research assistants, Sheron King and Tina
Ndoh, took the lead on workshop design, planning and organization. The workshop is
thought to be one of the first of its kind, eliciting governance, risk assessment, and
research needs around synthetic biology from environmental justice (EJ) community
members. The workshop included a diverse group of participants with expertise in
environmental law, federal government policies on EJ and community program,
academia and EJ advocacy and nonprofit organizations. Workshop participants
completed pre‐ and post‐surveys on governance needs and value and ethical
considerations for synthetic biology. They also engaged in round table discussions,
ordinal ranking of risk assessment needs and concept mapping exercises.
USDA Meeting
On March 12th and 13th, the GES Center hosted a two‐day USDA Stakeholder
Workshop on Coexistence with regard to GMOs, organic and conventional agriculture.
Sponsored mainly by a grant from USDA to the GES Center, this was an invitation‐only
meeting where participants talked about the future of GMOs, labeling bills throughout
the country and other issues faced by farmers and distributors. Various distinguished
names in the industry made presentations. US Secretary of Agriculture, Tom Vilsack
visited NC State and gave the keynote presentation to kick‐off the event. The Center
secured a USDA grant of approximately $31,000 to co‐host this meeting.
NSF Synthetic Biology Museum Partnership
Profs. Jennifer Kuzma (CFEP GES) and Jason Delborne (CFEP GES) are working
together with the Museum of Life and Science (MLS) in Durham, NC on a national NSF
grant to engage the public in synthetic biology, the “Multi‐Site Public Engagement with
Science – Synthetic Biology”. The Museum of Science in Boston is the lead organization,
along with partners at the American Association for the Advancement of Science, the
Synthetic Biology Engineering Research Center at Harvard‐MIT‐Berkeley, the Science
Museum of Minnesota, the Ithaca Science Center, MLS and several other universities
and museums. The aim of the project is to create conversations in science museums
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among scientists, engineers and public audiences about this emerging research field.
Synthetic biology applies science and engineering to create new biological systems and
re‐design existing biological systems, for useful purposes. Conversations between
researchers and public audiences will focus not only on what synthetic biology is and
how research in the field is carried out, but also on the potential products, outcomes
and implications for the society of this work. Researchers and the public will explore
personal and societal values and priorities, as well as desired research outcomes so that
both groups can learn from each other. Delborne and Kuzma assisted in the design,
review, and editing of the MLS Syn Bio 101 video in 2014 and will coordinate NC State
participation in the public focus groups taking place in summer 2015. NC State GES
faculty and IGERT students will assist with the public focus groups and synthetic
biology exhibits at the MLS in the summer of 2015. The center received a $2000 award
from the Multi‐Site Public Engagement with Science – Synthetic Biology Program to
support this effort.
World’s Fair Expo Partnership
The GES Center is a consulting partner with the USA Pavilion for the World’s Fair Expo
2015 in Milan, Italy. The focus of the USA Pavilion is American Food 2.0 and the issue
of GE foods is prominent in the pavilion. Prof. Kuzma has been working with the
organizers of the exhibit (lead by the VP of the James Beard Foundation) and was
interviewed for the video that will be placed at the beginning of the exhibit. She has
also provided expertise to the pavilion designers and staff about GMOs.
Issue Brief Series
The Center began to develop public education materials in 2014. Students and staff
wrote an issue brief on de‐extinction using synthetic biology, and it was reviewed by
several GES faculty. The first issue brief was released in August, 2015. The Center
intends to foster broad interactions with industry, non‐profits, NGOs, and
governmental organizations at the local, state, national and international level.
Appendix 1 provides a list of current Center partners.
Appendix1:ListofCurrentGESCenterPartners
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At NC State
Office of Research, Innovation & Economic Development
Office of the Provost
College of Agricultural and Life Sciences
College of Humanities and Social Sciences
College of Natural Resources
College of Science
NC State Library
NC State Library Archives
NC State History Department
William R. Kenan Jr. Institute for Engineering, Technology and Science
The W.M. Keck Center for Behavioral Biology
Park Scholars
University Scholars Program
Jefferson Scholars
Science, Technology and Society Program
Genetics Program
Local
NC Museum of Life and Science
NC Museum of Natural Science
University of North Carolina Public Policy
NC Farms Bureau
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Ag in the Classroom
Duke Science and Society
NC Biotech Center
National
University of California at Davis
University of California at Irvine
Colorado State University
Virginia Tech University
University of Michigan
Arizona State University
Texas A&M University
The Gordon Science and Technology Policy Research Conference
National Science Foundation IGERT program
Alfred P. Sloan Foundation
Glowing Plants
USDA
SynBio Project at Woodrow Wilson Center Washington DC
International
Nanyang Technological University – Singapore
Naval Medical Research Unit #6 –Lima and Iquitos, Peru
CIMMYT—Mexico
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World’s Fair Expo
CSIRO - Australia
Max Plank Institute - Jena, Germany
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Appendix2:FacultyInvolvedwiththeCenter
Name Department College
Charles Apperson Entomology CALS
Zach Brown Agricultural and Resource Economics CALS
Hannah Burrack Entomology CALS
Eric Davis Plant Pathology CALS
Rob Dunn Agricultural and Life Science CALS
George Kennedy Entomology CALS
Fred Gould Entomology CALS
Max Scott Entomology CALS
Michael Shulman Rural Sociology CALS
Wally Thurman Agriculture and Resource Economics CALS
Erin Banks Psychology CHASS
Jade Berry-James SPIA CHASS
David Berube Communications CHASS
Andrew Binder Communications CHASS
Matthew Booker History CHASS
Nick Haddad Anthropology CHASS
Nora Haenn Anthropology & International Studies CHASS
William Kimler History CHASS
William Kinsella Communications CHASS
Jennifer Kuzma SPIA CHASS
Kathleen Vogel Science and Technology Studies/SPIA CHASS
Kenneth Zagacki Communications CHASS
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Jason Delborne Science, Policy and Society CNR
Marian McCord Associate Dean for Research CNR
Nils Peterson Fisheries, Wildlife and Conservation Biology CNR
Louie Rivers Forestry CNR
Ronald R. Sederoff Forestry and Environmental Resources CNR
Robert Anholt Genetics COS
Dennis Brown Biochemistry COS
James Gilliam Biological Sciences COS
John Godwin Biological Sciences COS
Kevin Gross Statistics COS
Jane Hoppin Biological Sciences COS
Alun Lloyd Biomath COS
Marce Lorenzen Genetics COS
James Mahaffey Genetics COS
Administrators (Internal Advisory Committee)
Dean Richard Linton CALS
Dean Jeffrey Braden CHASS
Dean Mary Watzin CNR
Dean Dan Soloman COS
Vice Chancellor Terri Lomax ORIED (until Dec 2014)
Vice Chancellor Mladen Vouk ORIED (since Jan 2015)
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Vice Chancellor Alan Rebar ORIED (as of September 14)
Prof. Laura Severin Provost’s Office
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Appendix 3: External Advisory Committee
Advisor Affiliation
Maryann Feldman, Heninger Distinguished Professor in the Department of Public Policy
University of North Carolina — Chapel Hill
Erik Fisher, Assistant Director of International Activities
Arizona State University
Christy Flint, Coordinator of the Micro World Investigate Lab
North Carolina Museum of Natural Sciences
Michele Garfinkle, Science Policy Manager European Molecular Biology Organization (EMBO)
Jaydee Hanson, Policy Director International Center for Technology Advancement
John Hardin, Executive Director for the North Carolina Board of Science, Technology & Innovation
Office of Science, Technology & Innovation in the North Carolina Department of Commerce
Stephanie James, Director of Science for the Foundation for the National Institutes of Health
Bill and Melinda Gates Foundation
Todd Kuiken, Senior Program Associate with the Science and Technology Innovation Program
Woodrow Wilson International Centre for Scholars
Joe Magno, Executive Director North Carolina Biotechnology Center
Susan McCord, Executive Director Institute of Forest Biotechnology
Margaret Mellon, Science Policy Consultant Union of Concerned Scientists
Tichafa R. I. Munyikwa, Global Regulatory Affairs Lead
Syngenta
Mitch Peele, Senior Director Public Policy Farm Bureau — North Carolina
James Philp, Directorate for Science, Technology and Industry
Organization for Economic Co-operation and Development (OECD)
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Carl Pray, Distinguished Professor of Agricultural, Food and Resource Economics
Rutgers University
Jody Roberts, Director for the Institute for Research
Chemical Heritage Foundation
John Ryals, President, Chief Executive Officer and Chairman of the Board
Metabolon
Paul Thompson, Professor; W.K. Kellogg Chair in Agricultural, Food and Community Ethics
Michigan State University
Jacob Traverse, Director, Agbiotech Enterprise and Technology Development
North Carolina Biotechnology Center
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Appendix 4: Presentations
Speaker Title Location Date
Fred Gould Genetic Engineering for Suppressing Pests and Human Diseases
1st Annual Symposium of GE @ NC State
April 28, 2015
Fred Gould The Paradox of Evolutionary Diversification in the Lepidoptera
Annual meeting of Association for the Study of Chemical Senses-- Fort Meyers, Florida
April 24, 2015
Fred Gould Genetics and Society: From Vavilov to the Green Bunny
Univ. of Wisconsin – C. C. Doane Lecture
April 17, 2015
Fred Gould New Genome Editing Techniques: What They Mean for Applied Entomology
Univ. of Wisconsin Entomology April 16, 2015
Fred Gould Introduction to New RNAi Technologies
Revive and Restore workshop on “New Genomic Solutions for Conservation Problems Workshop”
April 7, 2015
Fred Gould Living in a Genetically Engineered World: With great Power Comes Great Responsibility
North Carolina School of Science and Math –Keynote address for the North Carolina Student Academy of Science
March 27, 2015
Fred Gould Presentation to NCSU Association of Retired Faculty on Genetic Engineering and Society: Where are we headed?
Presentation to NCSU Association of Retired Faculty
January 21, 2015
Fred Gould Making Pests Nicer Entomological Society of America
November 19, 2014
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Fred Gould Keynote –Founders’ Memorial Award Presentation
Entomological Society of America
November 16, 2014
Fred Gould Second generation crop genetic engineering
CIMMYT, Mexico July 24, 2014
Fred Gould Genomic approach for monitoring Bt resistance evolution
USDA BRAG Meeting June 5, 2014
Fred Gould History of the NCSU-GES Program Program Ag Biotech Forum (NC Biotech Center)
April 16, 2014
Fred Gould Genetic Engineering of Our Food and Pests
Osher Lifelong Learning Institute at Duke
April 8, 2014
Fred Gould NSF sponsored lecture on Genomics and Society
Texas A&M April 2, 2014
Fred Gould Ecological, Health and Social Issues related to GMOs
Texas A&M April 1, 2014
Fred Gould Park Scholars NC State March 19, 2014
Fred Gould Transicion de cultivos geneticamente modificados a insectos geneticamente modificados
Colegio de Postgraduados Campus Montecillo, Mexico
March 13, 2014
Jennifer Kuzma
A Mix of Ingredients: Factors Affecting Consumer Attitudes Toward Nano Food and Labeling.
Gordon Research Conference, Nanoscale Science and Engineering for Agriculture and Food Systems.
June 7-12, 2015
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Jennifer Kuzma
Risk and Media. Biotechnology Literacy Project Boot Camp
Academics Review, U of FL, and Genetic Literacy Project workshop. University of CA-Davis.
May 31-June 3, 2015.
Jennifer Kuzma
Intergenerational Equity, Gene Drives, and Conceptions of Nature
Governance of Emerging Technologies 3rd Annual Conference. Arizona State University
May 26-28, 2015
Jennifer Kuzma
Panelist for Ethics Education and Training in Science and Engineering Roundtable
The Rolf Buchdahl Symposium on Science, Technology, & Human Values at NC State
April 10, 2015
Jennifer Kuzma
Ethical, Legal, and Regulatory Considerations. New Genomic Solutions for Conservation Problems Workshop (plenary panel)
Long Now Foundation. Sausalito, CA
April 6 – 9, 2015
Jennifer Kuzma
Presentation on GM Food Safety Women’s Conference of National Farm Bureau
March 28, 2015
Jennifer Kuzma
Anticipatory Governance for Synthetic Biology: A Delphi Study
GES Colloquium, NC State March 24, 2015
Jennifer Kuzma
Gene Drives: Who’s Behind the Wheel?
Yale Bioethics Seminar March 3, 2015
Jennifer Kuzma
Ethics and Genetically Engineered Organisms
Duke Science and Society seminar
Feb. 25, 2015
Jennifer Kuzma
GE Food Safety and Public Perception. For “Finding Common Ground: The GM Food Labeling Paradox”
University of MN January 16, 2015
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Jennifer Kuzma (with C. Cummings)
Multidimensional risk profiling: A scenario-based evaluation of synthetic biology applications from a multidisciplinary expert Delphi study.
Society for Risk Analysis Annual Meeting,
December 8, 2014
Jennifer Kuzma
Responsible Development, Responsible Innovation: Global Governance of New Technologies. NSF sponsored Conference for Democratizing Technologies: Assessing the Roles of NGOs in Shaping Technological Futures
University of California, Santa Barbara
November 13-15, 2014
Jennifer Kuzma
Genetic Engineering and Society University Scholars Program (2 lectures for 300 students each),
November 10, 2014
Jennifer Kuzma
Anticipating Implications of Synthetic Biology
NSF Workshop on the Research Agendas in the Societal Implications of Synthetic Biology. ASU.
November 4-6, 2014
Jennifer Kuzma
Genetic Engineering and Society CHASS Advisory Board Meeting
November 2014
Jennifer Kuzma
Anticipation and its Relation to Responsibility
Wilson Center Roundtable on Responsible Innovation in Synthetic Biology. Washington, DC.
October 29, 2014
Jennifer Kuzma
GM Food and Safety Chef’s Collaborative (national conference for over 300 chefs).
September 29, 2014
Jennifer Kuzma
GMOs: Safety, Public, and Labeling
MN State Legislature briefing September 25, 2014
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Jennifer Kuzma
Policy Sciences and GE crops: Data and Information Needs
National Academy of Sciences National Research Council Study on GM Crops. Washington DC
September 16, 2014
Jennifer Kuzma
Regulation in a Rapidly Evolving Environment: Balancing Risk and Innovation.
2nd International Workshop for the Regulation of Animal Biotechnology. Invited for plenary by U.S. Dept. Agriculture. Brasilia, Brazil
August 21, 2014
Jennifer Kuzma
Governance of New Biotechnologies. International Maize and Wheat Improvement Center
CIMMYT, Mexico City, Mexico July 24, 2014
Jennifer Kuzma
Consumer Perceptions of Emerging Technologies in Food. International Conference on One Medicine One Science
University of Minnesota, Mpls, MN
April 29, 2014
Jennifer Kuzma
Genetic Engineering and Society at NCSU
NC Biotechnology Center kick-off event for Biotechnology Professionals
April 16, 2014
Jennifer Kuzma
Emerging Technologies and Food: What Matters to Most?
Center for Environmental and Natural Resource Economics & Policy, NCSU
April 11, 2014
Jennifer Kuzma
GM Food Panel Park Scholars Program April 2, 2014
Jennifer Kuzma
Genome Editing: On a Collision Course.
UNC-Chapel Hill Public Policy seminar
March 21, 2014
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Jennifer Kuzma
Beyond Old Debates: New Systems Risk Analysis (NESRA) in An Action-oriented Approach
National Academy of Sciences, Gordon and Betty Moore Foundation, Palo Alto, CA
March 13, 2014
Jennifer Kuzma
Genetic Engineering and Society Chancellor’s Reception UNC vs. NCSU game.
February 26, 2014
Zachary Brown
As we sow, so shall we sort? Using discrete choice sorting models to study GM crop adoption in the Philippines
USDA NIFA Multi-State Project on Risk and Insurance in Agriculture (SCC-76), Pensacola, FL,
March, 2015
Zachary Brown
Preference heterogeneity in the structural estimation of Pigovian incentives for insecticide spraying to reduce malaria
Virginia Tech, Dept of Forestry & Environmental Resources, Blacksburg, VA,
February, 2015
Zachary Brown
Training workshop on use of the Malaria Decision Analysis Tool
Dar es Salaam, Tanzania Dec 1-5, 2014
Zachary Brown
Presentation to OECD Working Party on Environmental Policy Regarding Household Responses to Environmental Policy
Sept. 29 – Oct. 16, 2014
Zachary Brown
World Congress of Environmental & Resource Economists
Istanbul June 28-July 2, 2014
Jason Delborne
Anticipating Responsible Innovation: Genetically-Modified Trees and Conceptualizations of Technological and Regulatory Futures
Third Annual Conference on Governance of Emerging Technologies: Law, Policy and Ethics. Scottsdale Resort and Conference Center, Scottsdale, AZ.
May 27, 2015
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Jason Delborne
Public Attitudes, Perceptions, and Engagement in the Field of Genetic Modification
First Annual GE @ NC State Symposium
April 28, 2015
Jason Delborne
Engaging Publics in Science and Technology: When Science and Citizens Connect: Public Engagement on Genetically Modified Organisms.
Workshop of the Roundtable on Public Interfaces of the Life Sciences (PILS), National Academy of Sciences, Washington, D.C
January 16, 2015
Jason Delborne
Biofuels, Biodiversity, and Responsible Innovation: The Case of Genetically Engineered Trees
Energy & Society Lecture Series, Arizona State University
November 4, 2014
Jason Delborne
Does Anticipating Futures Shape Governance? How One NGO Hopes to Predict and Shape Global Regulatory and Commercial Futures in the Creation of Genetically Modified Trees
NS-UCSB Democratizing Technologies Conference
November 1, 2014
Jason Delborne
Doubling Back on Risk Perception: Scientists, Genetically Modified Trees, and the Risks of Technological Rejection.
Society for Social Studies of Science. Buenos Aires, Argentina
August 23, 2014
Jason Delborne
Transgenics and Society: Towards a More Productive Dialogue
International Center for the Improvement of Maize and Wheat (CIMMYT), Texcoco, Mexico
July 23, 2014
Jason Delborne
Perspectives on Public Perceptions of Biotechnology
6th Annual Biotechnology Symposium, SUNY-ESF, Syracuse, NY.
May 15, 2014
Jason Delborne
Science, Democracy, and Public Engagement
International Center for the Improvement of Maize and Wheat (CIMMYT), Texcoco, Mexico
March 14, 2014
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David Berube
Tox 820B Lecture on Ethics of Synthetic Biology
NC State November 12, 2014
Matthew Booker
Introducing the GES History Project Rachel Carson Center, Ludwig Maximilian University, Munich
July 2014
Alun Lloyd Modeling Novel Strategies for Controlling Mosquito-Borne Diseases
UNC Greensboro October 10, 2014
Alun Lloyd Modeling Novel Strategies for Controlling Mosquito-Borne Diseases
University of Pretoria, South Africa
July 16, 2014
Marce Lorenzen
Genetics and Genomics of Tribolium Medea Elements
11th International Working Conference on Stored Product Protection, Chiang Mai, Thailand
November 25, 2014
Marce Lorenzen
Use of Genomic and Transcriptomic Data to Facilitate Germline Transformation of the Western Corn Rootworm
IWGO/Diabrotica Genetics Conference, Chicago, IL
April 14, 2014
Marce Lorenzen
Use of Next-Gen Sequencing for the Identification of Y-chromosome Derived Sequence Scaffolds in Red Flour Beetle, Tribolium castaneum, Genome
15th Annual Advances in Genome Biology and Technology meeting, Marco Island, Florida
February 14, 2014
Marce Lorenzen
Development of a Germline Transformation System for the Western Corn Rootworm, Diabrotica virgifera virgifera
NC205/NCCC46 Joint Meeting, Atlanta, GA
January 28, 2014
Max Scott Status of Developing the Genetically Modified Screwworm Strain(s)”.
XIV COPEG commissioners meeting, Washington DC
October 9, 2014
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Max Scott Transgenic sexing systems for genetic control of the New World screwworm Cochliomyia hominivorax
“10th European Congress of Entomology” in York, England
August 3-8, 2014
Max Scott Development and evaluation of male-only transgenic strains of the New World screwworm
Project Director’s meeting for the Biotechnology Risk Assessment Grants (BRAG) Program, Riverdale, MD
June 5, 2014
Max Scott Developing male-only strains of the screwworm and the Australian sheep blowfly
Center for Functional Genomics, Faculty of Medicine and Surgery, University of Perugia, Perugia, Italy
April 15, 2014
Max Scott Transgenic sexing systems for genetic control of the New World Screwworm and the Australian sheep blow fly
Fourth Research Co‐ordination Meeting (RCM) on the FAO/IAEA Co-ordinated Research Project “Development and Evaluation of Improved Strains of Insect Pests for SIT” in Capri, Italy
April 7-11, 2014
Ronald Sederoff
Biotechnology Training Program Annual Symposium
NCSU May, 2014
Ronald Sederoff
Department of Plant and Microbial Sciences
NCSU March, 2014
Ronald Sederoff
Session Chair on Sustainable Planted Forests
World Science Forum, Rio de Janeiro
November 2013
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Appendix 5: In the Media
Name Title and/or Source Date
Jennifer Kuzma Interviewed for and quoted in National Journal article on GM apple
February 19, 2015
Jennifer Kuzma Scientists Give Genetically Modified Organisms a Safety Switch
NPR - All Things Considered
January 21, 2015
Jennifer Kuzma NY Times—Gene Editing January 2, 2015
Jennifer Kuzma NPR - All Things Considered (Research featured and Kuzma Quoted )
December 6, 2014
Jennifer Kuzma Kuzma peer reviewed research study on GM food public perception quoted in several magazines and news venues, including Food Safety Magazine, Physics.org, Medical News, Food World News, Genetic Literacy Project, University Herald, Farm Futures, Science Daily, FeedStuffs Foodlink, etc
December 3, 2014
Jennifer Kuzma Quoted in Chem Eng News on GM potato November 17, 2014
Jennifer Kuzma Quoted in Chem Eng News on Synthetic Biology
November 10, 2014
Jennifer Kuzma Fred Gould, and Alison Wynn
North Carolina Now Covers the GES Center
UNC-TV
August 12, 2014
Fred Gould North Carolina Now Covers GMO Mosquitos
UNC-TV
August 11, 2014
Jennifer Kuzma NSF 360 Breaking News (quoted about peer-reviewed research that came out)
October 29, 2013
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Jennifer Kuzma Triangle Business Journal (quoted about peer-reviewed research that came out)
October 28, 2013
Jennifer Kuzma Quoted in Nature Magazine August 22, 2013
Jennifer Kuzma Interviewed for Chicago Public Radio on GM foods
July, 2013
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Appendix6:AcronymsUsedinGESCenterProposaltoEstablish(inorderofappearance)
CI Center/Institute
NC NorthCarolina
CGES CenteronGeneticEngineeringandSociety
GES GeneticEngineeringandSociety
NSF NationalScienceFoundation
IGERT InterdisciplinaryGraduateEducation,Research,andTraining(anNSF
graduatetrainingprogram)
GPM‐IGERT GeneticPestManagementIGERT
CFEPGESChancellor’sFacultyExcellenceProgramClusterinGeneticEngineeringand
Society
CALS CollegeofAgriculturalLifeSciences
CHASS CollegeofHumanitiesandSocialSciences
CNR CollegeofNaturalResources
COS CollegeofScience
GE GeneticEngineering
ATE AuthorizationtoEstablish
NGO Non‐GovernmentalOrganization
SETS Socio‐ecological–technologicalsystems
GEO GeneticallyEngineeredOrganism
DNA DeoxyribonucleicAcidGSK GlaxoSmithKlein
UNC UniversityofNorthCarolina
IGSP InstituteforGenomeSciencesandPolicy
STS ScienceTechnologyandSociety
ORIED OfficeofResearchInnovationandEconomicDevelopment
IAC InternalAdvisoryCommittee
EAC ExternalAdvisoryCommittee
EC ExecutiveCommittee
F&A FacilitiesandAdministration
USDA UnitedStatesDepartmentofAgriculture
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iGEM InternationalGeneticallyEngineeredMachines
SPIA SchoolofPublicandInternationalAffairs
FER ForestryandEnvironmentalResources
NR NaturalResources
EPA ExemptfromtheNorthCarolinaStatePersonnelAct
SPA StatePersonnelAct(NorthCarolina)
NCCOIN NCCenterofInnovationNetworkPI PrincipalInvestigator
RADAR NCStateResearchAdministrationDataandReportinginternalsystem
AAGES ArchivingAgriculturalGeneticEngineeringandSociety
APHIS AnimalandPlantHealthInspectionService
NOAA NationalOceanicAtmosphericAdministration
NIH NationalInstitutesofHealth
GM GeneticallyModified
DIYBio Do‐it‐yourselfBiology
GMO GeneticallyModifiedOrganism
BU BostonUniversity
CCMTR CenterforComparativeMedicineandTranslationalResearch
ASU ArizonaStateUniversity
MLS MuseumofLifeandScience
CIMMYT InternationalMaizeandWheatImprovementCenter
CIBIOGEM MexicanGMOregulatoryagency
GET GovernanceofEmergingTechnologies
SB SyntheticBiology
EJ EnvironmentalJusticeUS UnitedStates
MIT MassachusettsInstituteofTechnology
USA UnitedStatesofAmerica
VP VicePresident
RFP RequestforProposal
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Appendix7:EmailpresentedinsupportoffundingfortheGESCenterfromunitsoncampus
Email confirming support of CGES from CNR, CHASS, CALS, ORIED,
and the Provost
From: [email protected]
Date: February 6, 2013 5:37:25 PM EST
To: "Fred Gould" <[email protected]>, "Mary Watzin" <[email protected]>, "Jeffery Braden"
Cc: "Duane Larick" <[email protected]>
Subject: Re: Jennifer Kuzma offer
Reply‐To: [email protected]! Rich
‐‐‐‐‐‐Original Message‐‐‐‐‐‐
From: Fred Gould
To: Mary Watzin, Richard Linton, Jeffrey Braden
Cc: Duane Larick
Subject: Jennifer Kuzma offer
Sent: Feb 6, 2013 5:33 PM
Dear Deans Watzin, Linton, and Braden,
With verbal commitments from each of you to provide $50K/year for five years to
support building a Genetic Engineering and Society center, I was able to approach the upper
administration for the final $100K/year for five years.
I am pleased to say that Provost Arden and Vice Chancellor Lomax are together
willing to commit that amount. Before they make that commitment they would like to have an email
commitment from each of you for your share. This only needs to be one or two lines in response
to this email.
Thanks again for your support.
Fred Gould
===========================================================================
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From: Daniel Solomon <[email protected]>
Subject: Re: Genetic Engineering and Society Internal Advisory Committee
Date: May 2, 2014 11:13:18 AM EDT
To: Fred Gould <[email protected]>
Cc: Jennifer Kuzma <[email protected]>, "Cohen, Jo-Ann" <[email protected]>, Katie Perry
<[email protected]>, "Krim, Jacqueline" <[email protected]>, "Stallings, Anita" <[email protected]>
Fred,
Further to my inquiry at the beginning of the week, I've got commitments from Biological Sciences,
Mathematics and the College to support a total of $30K/year for five years in cash. Are there
opportunities for in-kind support for the other $20K? We do want to be at the table, but our financial
situation following the college transition is still shaking out.
Thanks,
Dan
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Appendix 8: Estimated 5 Year Budget and Expenditures
Estimated 5 Year Budget (US $)
Fiscal Years
Contracts and Grants
Support from NC State Donations Total
FY 2015 Actual 777,228 280,000 22,000 1,079,228
FY2016 Estimated 987,584 280,000 20,000 1,287,584
FY2017 Estimated 427,020 280,000 25,000 732,020
FY2018 Estimated 193,472 280,000 25,000 498,472
FY2019 Estimated 6,823 0 25,000 31,823
Total estimated funding
2,392,127 1,120,000 117,000 3,629,127
Estimated 5 Year Expenditures (US $)
Fiscal Years
Salaries and Fringes
Educational Supplies
Travel
Current Services
Other Operating Expenses
Total
FY 2015Actual 142,200 31,500 29,850 537,000 59,500 800,050 FY 2016 Estimated
168,110 31,000 40,850 644,500 50,500 934,960
FY 2017 Estimated
172,289 5,000 30,000 275,000 30,000 512,289
FY 2018 Estimated
176,769 1,000 10,000 125,000 20,000 332,769
FY 2019 Estimated
181,748 1,000 4,000 100,000 20,000 306,748
Total estimated expenditures
841,116 69,500 114,700 1,681,500 180,000 2,886,816