research, funding and grantsmanship: fellowship to...

Research, FundingResearch, Funding

and and GrantsmanshipGrantsmanship:: Fellowship to Assistant Professor Fellowship to Assistant Professor

--

Postdoctoral Training ProgramPostdoctoral Training Program in Cardiovascular Disease in Cardiovascular Disease --

November 25, 2013November 25, 2013

Jaime S. Rubin, [email protected], 342-3184

Dept. of MedicineCollege of Physicians and Surgeons

Columbia University

Types of AwardsTypes of Awards

Fellowships (FFellowships (F’’s), Training grants (Ts), Training grants (T’’s), Career s), Career Development awards (Development awards (KK’’ss), Research grants (R), Research grants (R’’s), s), Loan Repayment ProgramLoan Repayment Program

Funding AgenciesFunding Agencies

FederalFederalNational Institutes of Health, National Institutes of Health, AHRQAHRQ, HRSA, HRSA

Voluntary Health Organizations, Professional Voluntary Health Organizations, Professional Societies, Foundations, Industry, OtherSocieties, Foundations, Industry, Other

Planning & Organizing a Research ProposalPlanning & Organizing a Research Proposal

Topics to be DiscussedTopics to be Discussed

National Institutes of HealthNational Institutes of Health

Adapted from: NIH (DRG) Adapted from: NIH (DRG) --

Peer Review of NIH Research Grants ApplicationsPeer Review of NIH Research Grants Applications

NationalInstituteon Aging

National Instof Allergy &

InfectiousDiseases

National Instof AlcoholAbuse &

Alcoholism

NationalCancerInstitute

NationalEye

Institute

National Heart,Lung,

& Blood Institute

National HumanGenome

Research Inst

National Inst of Arthritis &

Musculoskeletal &Skin Diseases

National Instituteof Child Health

& Human Development

National Inst on Deafness & otherCommunication

Disorders

National Instof Dental &Craniofacial

Research

National Instituteof Diabetes &Digestive &

Kidney Diseases

NationalInstituteon DrugAbuse

NationalInstitute of

EnvironmentalHealth Sciences


GeneralMedical Sciences


Mental Health

National Inst ofNeurological

Dis and Stroke


Nursing Research

NationalLibrary

of Medicine

National Ctr forComplementary & Alt Medicine

John E. FogartyInternational

Center

Officeof the

Director

Center for ScientificReview

Center forInformationTechnology

NIHClinicalCenter

National Inst of Biomedical

Imaging andBioengineering

National Inst on Minority Health & Health Disparities

National Ctr Adv Translational

Sciences


Fellowships (FFellowships (F’’s), Training grants (Ts), Training grants (T’’s), Career s), Career Development awards (Development awards (KK’’ss), Research grants (R), Research grants (R’’s), s), Loan Repayment ProgramLoan Repayment Program


FederalFederalNational Institutes of Health, National Institutes of Health, AHRQAHRQ, HRSA, HRSA

Voluntary Health Organizations, Professional Voluntary Health Organizations, Professional Societies, Foundations, Industry, OtherSocieties, Foundations, Industry, Other



Not All FundingNot All Funding Opportunities Are the SameOpportunities Are the Same

Different mission statementsDifferent mission statements

Career development (Career development (KK’’ss))

Research project (RResearch project (R’’s)s)

Different fundingDifferent funding

Stipend/SalaryStipend/Salary

Comprehensive research costsComprehensive research costs

Different time framesDifferent time frames

Not renewable: 5 years (Not renewable: 5 years (KK’’ss), 3 years (F), 3 years (F’’s), 2 years (Ts), 2 years (T’’s)s)

Renewable: 4yearsRenewable: 4years--5years (R01) each competitive period5years (R01) each competitive period


Individual fellowshipsIndividual fellowships

Training grantsTraining grants

Career transition awardsCareer transition awards

Career development Career development awardsawards

Research grantsResearch grants

Institutional Clinical & Institutional Clinical & Translational Science Translational Science Award (CTSA)Award (CTSA)

Loan Repayment Loan Repayment ProgramProgram

Administrative Administrative supplementssupplements

Program ProjectsProgram Projects

Cooperative agreementsCooperative agreements

SubcontractsSubcontracts

ContractsContracts

Medical SchoolInternship/ Residency

Fellowship –

Research Years

Instructor/ Assistant Professor

T35 Training GrantSummer Research between 1st and 2nd

Years

CareerTransition

Award

Year-long “Enhancement”

Research Program

Individual Post-doc Fellowship or

Institutional Post-doc Training Grant slot

Institutional K12 Career

Development Slot

IndividualMentored K

Career Development

Award

Timeline of Funding forTimeline of Funding for Junior InvestigatorsJunior Investigators

K08/K23

K23K12

K12 Independent Grant

K12 K23

Independent Grant

Independent Grant

K08/K23 Independent Grant

NIH Career Development SupportNIH Career Development Support to Independent Research Fundingto Independent Research Funding

Independent Grant

Independent Investigator

R01Research Award

Funds research project• Salaries of PI and other research personnel• Supplies, reagents, etc• Animal costs• Patient care costs• Core facilities• Page charges for publicationsMulti-Year (4yrs – 5yrs)Renewable (e.g. original grant + 2 renewals = 15yrs)


Fellowship –

Research Years



Years

CareerTransition

Award


Research Program



Timeline of NIH Funding for Timeline of NIH Funding for Junior InvestigatorsJunior Investigators

Career Transition AwardsCareer Transition Awards

BWF: Career Awards for Medical ScientistsBWF: Career Awards for Medical Scientists

To support To support physicianphysician--scientistsscientists

during the last years of a during the last years of a mentored postdoctoral/fellowship position and the mentored postdoctoral/fellowship position and the beginning years of an independent faculty position.beginning years of an independent faculty position.

Must hold an M.D., D.D.S., D.V.M., Must hold an M.D., D.D.S., D.V.M., Pharm.DPharm.D., or ., or equivalent clinical degreeequivalent clinical degree

75% effort to research75% effort to research--related activitiesrelated activities

Funding: $700,000 over five yearsFunding: $700,000 over five years

Postdoctoral/Fellowship Portion: Years 1 and 2Postdoctoral/Fellowship Portion: Years 1 and 2 Annual Total: $95,000Annual Total: $95,000

Faculty Portion of the Award: Years 3Faculty Portion of the Award: Years 3--55 Annual Total: $170,000 Annual Total: $170,000


NIH Pathway to Independence Award NIH Pathway to Independence Award (K99/R00)(K99/R00)

11--2 years as a mentored K award for post2 years as a mentored K award for post--docsdocs

Total/year: =$90,000 (salary and research expenses)Total/year: =$90,000 (salary and research expenses)

75% effort75% effort

3 years as an research support award for independent 3 years as an research support award for independent investigatorsinvestigators

Total/year:=$249,000 (salary and research expenses)Total/year:=$249,000 (salary and research expenses)

Must have an independent research positionMust have an independent research position

Fund 150Fund 150--200 awards per year200 awards per year


American Heart AssociationAmerican Heart Association

((National) National)

FellowFellow--toto--Faculty Transition AwardFaculty Transition Award

Provides funding for the crucial period of a Provides funding for the crucial period of a physicianphysician-- scientistscientist’’s career developments career development

which spans the which spans the

completion of research training through the early years completion of research training through the early years of the first faculty/staff positionof the first faculty/staff position

Training stage (1Training stage (1--3 yrs, $65,000 per year) and the first 3 yrs, $65,000 per year) and the first years of the first faculty/staff appointment ($132,000 years of the first faculty/staff appointment ($132,000 per year), for a maximum of five years of supportper year), for a maximum of five years of support

Citizenship: U.S. citizen/ Permanent resident/ Pending Citizenship: U.S. citizen/ Permanent resident/ Pending permanent resident, Visas (e.g. H1permanent resident, Visas (e.g. H1--B, OB, O--1)1)


Fellowship –

Research Years



Years

CareerTransition

Award


Research Program




Career Development

Award


Research Career Programs (K)Research Career Programs (K)

Minimum Effort: e.g. 75% (sometimes 50%)Minimum Effort: e.g. 75% (sometimes 50%)Research & Career development activitiesResearch & Career development activities

Predominantly salary supportPredominantly salary support

Up to 5 yearsUp to 5 years

US citizen/permanent residentUS citizen/permanent resident

Reduce effort to 50% in last 2 years if PI of NIH Reduce effort to 50% in last 2 years if PI of NIH research grantresearch grant

Mentored Clinical Scientist Mentored Clinical Scientist Development Award (K08)Development Award (K08)

Support to develop outstanding Support to develop outstanding independent clinician research scientistsindependent clinician research scientists

Basic and translational scienceBasic and translational science

Mentored PatientMentored Patient--Oriented ResearchOriented Research

Career Development Award (K23)Career Development Award (K23)

Patient-oriented research::

Research conducted Research conducted

with human subjects (or on material of human with human subjects (or on material of human origin) for which an investigator directly interacts origin) for which an investigator directly interacts with human subjectswith human subjects

Research areas:

(1) Mechanisms of human (1) Mechanisms of human

disease, (2) Therapeutic interventions, (3) Clinical disease, (2) Therapeutic interventions, (3) Clinical trials, and (4) Development of new technologiestrials, and (4) Development of new technologies

Mentored Research ScientistMentored Research Scientist Development Awards (K01)Development Awards (K01)

NHLBINHLBI: :

DiversityDiversity

NHLBINHLBI: :

(a) Epidemiological Research(a) Epidemiological Research

(b) Biostatistics Research(b) Biostatistics Research

(c) Comparative Effectiveness Research (c) Comparative Effectiveness Research

Research Career Development AwardsResearch Career Development Awards

Research Career Development AwardsResearch Career Development Awards

http://nexus.od.nih.gov/all/wp-content/uploads/2011/10/k awards 32.jpg

http://report.nih.gov/fundingfacts/fundingfacts.aspx

NHLBI: K23 awards NHLBI: K23 awards --

Success RatesSuccess Rates

Agency for Healthcare Research and Agency for Healthcare Research and Quality (AHRQ)Quality (AHRQ)

Mentored Clinical Scientist Development Awards (K08)Mentored Clinical Scientist Development Awards (K08)

PatientPatient--Centered Outcomes Research (PCOR) Mentored Centered Outcomes Research (PCOR) Mentored Clinical Investigator Award (K08)Clinical Investigator Award (K08)

PatientPatient--Centered Outcomes Research (PCOR) Mentored Centered Outcomes Research (PCOR) Mentored Research Scientist Development Award (K01)Research Scientist Development Award (K01)


Fellowship –

Research Years



Years

CareerTransition

Award


Research Program




Development Slot


Career Development

Award


Mentored Clinical ScientistMentored Clinical Scientist

Development Program Award (K12)Development Program Award (K12)

Support to an Support to an institutioninstitution

for career for career

development experiences for clinicians leading development experiences for clinicians leading to research independenceto research independence

Institutions recruit and select candidatesInstitutions recruit and select candidates

into into

their programstheir programs

Candidates must meet the Candidates must meet the same criteria as for same criteria as for the individual mentored clinical scientistthe individual mentored clinical scientist

development awarddevelopment award

Trial DesignTrial Design

AdvancedAdvancedDegreeDegree--GrantingGrantingProgramsPrograms

ParticipantParticipant& Community& CommunityInvolvementInvolvement

RegulatoryRegulatorySupportSupport

BiostatisticsBiostatistics

ClinicalClinicalResourcesResources

BiomedicalBiomedicalInformaticsInformatics

ClinicalClinicalResearchResearch

EthicsEthics

CTSACTSAHOMEHOME

NIHNIH

OtherOtherInstitutionsInstitutions

IndustryIndustry

CTSA Awards: CTSA Awards: A Home for Clinical and Translational ScienceA Home for Clinical and Translational Science

Source: Zerhouni (NIH) [9/06]

Mentored Clinical ScientistMentored Clinical Scientist

Development Program Award (K12)Development Program Award (K12)

CTSA CTSA --

Clinical and Translational Clinical and Translational

Scientist AwardScientist Award

TRANSFORM Scholars Mentored TRANSFORM Scholars Mentored Career Development program Career Development program [Training and Nurturing Scientists for [Training and Nurturing Scientists for Research that is Multidisciplinary]Research that is Multidisciplinary]

Degree Program in Degree Program in

PatientPatient--Oriented Research [POR]Oriented Research [POR]

Comprehensive courses in clinical researchComprehensive courses in clinical research

Biostatistics, epidemiology, study designs, Biostatistics, epidemiology, study designs, bioethics, legal and regulatory issues bioethics, legal and regulatory issues

For the career development of clinical For the career development of clinical investigatorsinvestigators

Research Career Development/ Research Career Development/ Scholar ProgramsScholar Programs

American Heart Association

Scientist Development Grant

Doris Duke Charitable Foundation

Clinical Scientist Development

Robert Wood Johnson Foundation

Harold Amos Medical Faculty Development Program

NIH CareerNIH Career Development (K ) ApplicationDevelopment (K ) Application

Model for other career development/ Model for other career development/ scholar grant programs supported by scholar grant programs supported by voluntary health organizations, private voluntary health organizations, private foundations, and professional societiesfoundations, and professional societies

The CandidateThe Candidate

CandidateCandidate’’s Backgrounds Background

Career Goals and Objectives: Career Goals and Objectives: Scientific BiographyScientific Biography

CandidateCandidate’’s Backgrounds Background

Personal background for this career pathPersonal background for this career path

Other relevant training experiencesOther relevant training experiences

Other research experiencesOther research experiences

Reasons for basic, clinical, translational, Reasons for basic, clinical, translational, behavioral, multidisciplinary research, relevant behavioral, multidisciplinary research, relevant publicationspublications

Career Goals and ObjectivesCareer Goals and Objectives

Unique expertise/Scientific historyUnique expertise/Scientific history

Skills that are lackingSkills that are lacking

ShortShort--term Career Goalsterm Career Goals

Timeline for funded periodTimeline for funded period

LongLong--term Career Goalsterm Career Goals

Scientific goalsScientific goals

Mentoring goalsMentoring goals

Networking goalsNetworking goals

Career Development/TrainingCareer Development/Training Activities During Award PeriodActivities During Award Period

Review of didactic courses, clinical training, and Review of didactic courses, clinical training, and research experiences to dateresearch experiences to date

New research skills/ knowledge requiredNew research skills/ knowledge required

Identification of training modules required to fill Identification of training modules required to fill gaps in knowledge in order to reach long term gaps in knowledge in order to reach long term goalsgoals

Mentors, Courses, Workshops and additional training, Mentors, Courses, Workshops and additional training, Conferences, Communication skills, Grant writingConferences, Communication skills, Grant writing

Mentors/Advisory CommitteeMentors/Advisory Committee

Collaborators and ConsultantsCollaborators and Consultants

Scientific area per mentor/committee memberScientific area per mentor/committee member

Schedule of meetingsSchedule of meetings

Career Development and Research TrainingCareer Development and Research TrainingMentors and AdvisorsMentors and Advisors

Faculty MemberFaculty Member RoleRole Area of ExpertiseArea of ExpertiseName (Title)Name (Title) MentorMentorName (Title)Name (Title) CoCo--MentorMentorName (Title)Name (Title) Advisory Board MemberAdvisory Board MemberName (Title)Name (Title) Advisory Board MemberAdvisory Board MemberName (Title)Name (Title) Advisory Board MemberAdvisory Board MemberName (Title)Name (Title) CollaboratorCollaboratorName (Title)Name (Title) ConsultantConsultant

Environment and InstitutionalEnvironment and Institutional Commitment to the CandidateCommitment to the Candidate

Description of Institutional EnvironmentDescription of Institutional Environment

Institutional Commitment to the CandidateInstitutional Commitment to the Candidate’’s s Research Career DevelopmentResearch Career Development


Fellowship –

Research Years



Years

CareerTransition

Award


Research Program




Development Slot


Career Development

Award


NIH Loan Repayment Program

NIHNIH’’ss

ExtramuralExtramural Loan Repayment ProgramLoan Repayment Program

Up to $35,000 a year towards educational loan debtUp to $35,000 a year towards educational loan debt

Conduct qualified research activities for at least 50% Conduct qualified research activities for at least 50% of their effort (or less than 20 hours per week) for a of their effort (or less than 20 hours per week) for a minimum of 2 yearsminimum of 2 years

Qualifying educational loan debt equals or exceeds Qualifying educational loan debt equals or exceeds 20% of the applicant's institutional base salary20% of the applicant's institutional base salary

NIHNIH’’ss

ExtramuralExtramural Loan Repayment ProgramLoan Repayment Program

Extramural ProgramsExtramural Programs

Clinical ResearchClinical Research

Health Disparities ResearchHealth Disparities Research

Clinical Researchers from Clinical Researchers from Disadvantaged BackgroundsDisadvantaged Backgrounds

Pediatric ResearchPediatric Research

Contraception and Infertility ResearchContraception and Infertility Research

LRP: Clinical Research LRP: Clinical Research ––

New Applications New Applications --

http://www.lrp.nih.gov/about_the_programs/clinical.aspx

LRP: Clinical Research LRP: Clinical Research ––

Renewal Applications Renewal Applications --

http://www.lrp.nih.gov/about_the_programs/clinical.aspx

HRSAHRSA Loan Repayment ProgramsLoan Repayment Programs

Health Resources and Services Administration/ Health Resources and Services Administration/ Faculty Loan Repayment ProgramFaculty Loan Repayment Program

Health professions faculty from disadvantaged Health professions faculty from disadvantaged backgroundsbackgrounds

agree to serve at a health professions agree to serve at a health professions

college/university for 2 years. Federal government will pay college/university for 2 years. Federal government will pay up to $40,000 of the participant's student loans and up to $40,000 of the participant's student loans and provides funds to offset the tax burden.provides funds to offset the tax burden.

K08/K23

K23K12

K12 Independent Grant

K12 K23

Independent Grant

Independent Grant

K08/K23 Independent Grant

NIH Career Development SupportNIH Career Development Support to Independent Research Fundingto Independent Research Funding

Independent Grant

Independent Investigator

R01Research Award

Funds research project• Salaries of PI and other research personnel• Supplies, reagents, etc• Animal costs• Patient care costs• Core facilities• Page charges for publicationsMulti-Year (4yrs – 5yrs)Renewable (e.g. original grant + 2 renewals = 15yrs)

R01 Research GrantR01 Research Grant

Supports a discrete, specified projectSupports a discrete, specified project

““ComprehensiveComprehensive””

fundingfunding

Modular budgets up to $250,000/yearModular budgets up to $250,000/year

MultiMulti--yearyear

FlexibilityFlexibility

Most of the research that NIH supports is Most of the research that NIH supports is through this funding mechanismthrough this funding mechanism

R01R01--Equivalent grants: Equivalent grants: Applications, Awards, and Success RatesApplications, Awards, and Success Rates

Exploratory/Developmental Exploratory/Developmental Grants (R21Grants (R21))

Encourages new, exploratory, and Encourages new, exploratory, and developmental researchdevelopmental research

Pilot and feasibility studiesPilot and feasibility studies

2 years of funding 2 years of funding

Budget: $275,000 over two yearsBudget: $275,000 over two years

Not renewableNot renewable

Small Research Grants (R03)Small Research Grants (R03)

Supports:Supports:

Pilot or feasibility studiesPilot or feasibility studies

Collection of preliminary dataCollection of preliminary data

Secondary analysis of existing dataSecondary analysis of existing data

Small, selfSmall, self--contained research projectscontained research projects

Development of new research technologyDevelopment of new research technology

2 years of funding 2 years of funding

Budget: $50,000/yearBudget: $50,000/year

Not renewableNot renewable

http://www.brokenpipeline.org/brokenpipeline.pdf

http://enhancing-peer-review.nih.gov/meetings/Peer%20Review%20Implementation%20FINAL%20DRAFT%20update%20-%20ACD%20mtg%206-6-08.pdf

NIH R01 Principal Investigators:NIH R01 Principal Investigators:

Age 36 and Younger / Age 66 and OlderAge 36 and Younger / Age 66 and Older

http://nexus.od.nih.gov/all/rock-talk/

Early Stage InvestigatorsEarly Stage Investigators

No previous No previous ““significant NIH independent significant NIH independent research awardresearch award””

e.g. R01e.g. R01’’ss

Does not include: FDoes not include: F’’s, s, KK’’ss, loan repayment program, loan repayment program

Within 10 years of terminal research degree/ Within 10 years of terminal research degree/ completion of medical residencycompletion of medical residency

Extensions permittedExtensions permitted

Additional clinical trainingAdditional clinical training

Family responsibilitiesFamily responsibilities

Early Stage Investigators: NHLBIEarly Stage Investigators: NHLBI

FY13http://www.nhlbi.nih.gov/funding/policies/operguid.htm

R01R01--

Equivalent grants, New (Type 1)

Equivalent grants, New (Type 1)

Success rates, by career stage of investigatorSuccess rates, by career stage of investigator


Fellowships (FFellowships (F’’s), Training grants (Ts), Training grants (T’’s), Career s), Career Development awards (Development awards (KK’’ss), Research grants (R), Research grants (R’’s), Loan s), Loan Repayment ProgramRepayment Program


FederalFederalNational Institutes of Health, AHRQ, HRSANational Institutes of Health, AHRQ, HRSA

Voluntary Health Organizations, Professional Societies, Voluntary Health Organizations, Professional Societies, Foundations, Industry, OtherFoundations, Industry, Other



Voluntary Health OrganizationsVoluntary Health Organizations

American Heart AssociationAmerican Heart Association

NationalNational

Collaborative Science AwardCollaborative Science Award

Mentored & Clinical Population Research AwardMentored & Clinical Population Research Award

FellowFellow--toto--Faculty Transition AwardFaculty Transition Award

Scientist Development GrantScientist Development Grant

Founders AffiliateFounders Affiliate

GrantGrant--inin--AidAid

Mentored & Clinical Population Research AwardMentored & Clinical Population Research Award

Scientist Development GrantScientist Development Grant

Postdoctoral FellowshipPostdoctoral Fellowship

PredoctoralPredoctoral

FellowshipFellowship

Undergraduate Student Summer Fellowship ProgramUndergraduate Student Summer Fellowship Program

Medical Student Research ProgramMedical Student Research Program

Professional SocietiesProfessional Societies

American College of Cardiology (ACC)/ACCFAmerican College of Cardiology (ACC)/ACCF

Merck Research Fellowships in Cardiovascular Disease Merck Research Fellowships in Cardiovascular Disease and and CardiometabolicCardiometabolic

DisordersDisorders

$70,000 salary support for one year of research$70,000 salary support for one year of research

William F. Keating, Esq. Endowment AwardWilliam F. Keating, Esq. Endowment Award


International Society for Cardiovascular Translational International Society for Cardiovascular Translational Research (ISCTR) Cardiovascular Translational Research (ISCTR) Cardiovascular Translational Research ScholarshipResearch Scholarship


Young Investigator Awards CompetitionYoung Investigator Awards Competition

Private FoundationsPrivate Foundations

Doris Duke Charitable Foundation

Clinical Scientist Development

Robert Wood Johnson Foundation

Harold Amos Medical Faculty Development Program


Fellowships (FFellowships (F’’s), Training grants (Ts), Training grants (T’’s), Career s), Career Development awards (Development awards (KK’’ss), Research grants (R), Research grants (R’’s), Loan s), Loan Repayment ProgramRepayment Program


FederalFederalNational Institutes of Health, AHRQ, HRSANational Institutes of Health, AHRQ, HRSA

Voluntary Health Organizations, Professional Societies, Voluntary Health Organizations, Professional Societies, Foundations, Industry, OtherFoundations, Industry, Other



When Preparing an Application:When Preparing an Application:

Read instructionsRead instructions

Never assume that reviewers Never assume that reviewers ““will know what will know what you meanyou mean””

Refer to literature thoroughly and Refer to literature thoroughly and thoughtfullythoughtfully

Explicitly state the rationale of the proposed Explicitly state the rationale of the proposed investigationinvestigation

Include wellInclude well--designed tables and figuresdesigned tables and figures

Present an organized, lucid writePresent an organized, lucid write--upup

Elements of a Good ProposalElements of a Good Proposal

FeasibleFeasible

RelevantRelevant

UniqueUnique

InnovativeInnovative

ClearClear

BriefBrief

ConsistentConsistent

Anticipate QuestionsAnticipate Questions

andand

Answer them beforeAnswer them before

they are askedthey are asked

InvestigatorInvestigator

CompetentCompetent

EnthusiasticEnthusiastic

ThoroughThorough

ProfessionalProfessional

NIH: one round of applicationsNIH: one round of applications

http://www3.cancer.gov/admin/gab/02gpb/nci_grants_bk.pdf

Pink Sheet: Reviewers’ Comments

GreatGreat

Definitely fund

Definitely do not fund

Bell Curve of Reviewer’s Grant Applications

Fine

Poor Statistics

Research Resourcesnot Adequately Described

Career Development Plannot Comprehensive

Figure Caption Font too Small

All Components of the Application are as Strong as Possible

Common Problems with Grant Common Problems with Grant Applications from New InvestigatorsApplications from New Investigators

Overly ambitiousOverly ambitious

Not independent of previous mentorNot independent of previous mentor’’s researchs research

Fishing expeditionFishing expedition

Not hypothesis drivenNot hypothesis driven

Descriptive, not mechanistic projectDescriptive, not mechanistic project

UnfocussedUnfocussed

No or insufficient preliminary dataNo or insufficient preliminary data

Unrealistic budgetUnrealistic budget

Methodologies beyond the expertise of investigator Methodologies beyond the expertise of investigator or research teamor research team

Good Luck!Good Luck!

research, funding and grantsmanship: fellowship to...

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