Research & Reviews : A Journal of

Unani, Siddha & Homeopathy

STM JOURNALSScientific Technical Medical

Jan - April 2014

www.stmjournals.com

(RRJoUSH)

STM Publication, a strong initiative by Consortium E-Learning Network Private ltd.(Estd. 2006) was

launched in the year 2010 under the support and guidance by our esteemed Editorial and Advisory board

members from renowned institutes.

Objectives of STM Publication(s):

† Scientific, Technical and Medical research promotions.

† Publication of genuine Research/Review, Short Articles and Case Studies through proper review

process.

† Publishing Special Issues on Conferences.

† Preparing online platform for other print Journals.

† Empowering the libraries with online and print Journals in Scientific, Technical and Medical

domains.

† Publishing and distribution of books on various subjects which mainly falls in the category of

Nanotechnology, Scientific and technical writing & Environment, Health and Safety.

Salient Features:

† A bouquet of 100+ Journals that fall under Science, Technical & Medical domains.

† Employs Open Journals System (OJS) A Journal Management & Publishing System.

† The first and one of the fastest growing publication website in India as well as in abroad for its quality

and coverage.

† Rapid online submission and publication of papers, soon after their formal acceptance/ finalization.

† Facilitates linking with the other authors or professionals.

† Worldwide circulation and visibility.

Research &Reviews : A Journal of Unani, Siddha and Homeopathy

Focus and Scope Covers

† Ilaj-Bil-Ghiza (Regimenal Therapy)

† Research designs, Research Relevant to Unani System of Medicine

† Gunapadam (Siddha Pharmacology)

† Maruthuvam (Medicine)

† Isopathy

† Electrohomeopathy

† Health, ethical and social issues in field of Homoeopathy research

Research &Reviews : A Journal of Unani, Siddha and Homeopathy is published (frequency: three times a year) in India

by STM Journals (division of Consortium e-Learning Network Private Ltd. Pvt.) The views expressed in the articles do

not necessarily reflect of the Publisher. The publisher does not endorse the quality or value of the advertised/sponsored

products described therein. Please consult full prescribing information before issuing a prescription for any products

mentioned in this publication.

No part of this publication may be reproduced, stored in retrieval system or transmitted in any from without written

permission of the publisher.

To cite any of the material contained in this Journal, in English or translation, please use the full English reference at the

beginning of each article. To reuse any of the material, please contact STM Journals (info@stmjournals.com)

STM Publication(s)

STM Journals (division of Consortium e-Learning Network Private Ltd. ) having its Marketing office located at Office

No. 4, First Floor, CSC pocket E Market, Mayur Vihar Phase II, New Delhi-110091, India is the Publisher of Journal.

Statements and opinions expressed in the Journal reflect the views of the author(s) and are not the opinion of STM

Journals unless so stated.

Subscription Information and Order:

Cost of Journal:

— National Subscription: Rs. 3750/- per Journal (includes 3 print issues), Single Issue copy purchase Rs.1500/copy

— International Subscription:

— Online Only- $99, Print Only-$149 (includes 3 print issues)

— Online + Print-$199 (includes 3 print issues + online access of published back volumes )

To purchase print compilation of back issues please send your query at info@stmjournals.com

Subscription must be prepaid. Rates outside the India includes speed delivery charges. Prices subject to change

without notice.

Mode of Payment: At par cheque, Demand draft, and RTGS (payment to be made in favor of

Consortium E-Learning Network. Pvt. ltd., payable at Delhi/New Delhi.

Online Access Policy

A). For Authors:

In order to provide maximum citation and wide publicity to the authors work, STM Journals also have Open Access

Policy, authors who would like to get their work open access can opt for Optional Open Access publication at

nominal cost as follows

India, SARC and African Countries: INR 2500 or 100 USD including single hard copy of Author's Journal.

Other Countries: USD 200 including single hard copy of Author's Journal.

B.) For Subscribers:

— Online access will be activated within 72 hours of receipt of the payment (working days), subject to receipt of

correct information on user details/Static IP address of the subscriber.

— The access will be blocked:

— If the user requests for the same and furnishes valid reasons for blocking.

— Due to technical issue.

— Misuse of the access rights as per the access policy.

Advertising and Commercial Reprint Inquiries: STM Journals with wide circulation and visibility offer an excellent

media for showcasing/promotion of your products/services and the events-namely, Conferences, Symposia/Seminars

etc. These journals have very high potential to deliver the message across the targeted audience regularly with each

published issue. The advertisements on bulk subscriptions, gift subscriptions or reprint purchases for distribution etc. are

also very welcome.

Lost Issue Claims: Please note the following when applying for lost or missing issues:

— Claims for print copies lost will be honored only after 45 days of the dispatch date and before publication of the

next issue as per the frequency.

— Tracking id for the speed post will be provided to all our subscribers and the claims for the missing Journals will

be entertained only with the proofs which will be verified at both the ends.

— Claims filed due to insufficient (or no notice) of change of address will not be honored.

— Change of Address of Dispatch should be intimated to STM Journals at least 2 months prior to the dispatch

schedule as per the frequency by mentioning subscriber id and the subscription id.

— Refund requests will not be entertained.

Legal Disputes

All the legal disputes are subjected to Delhi Jurisdiction only.

If you have any questions, please contact the Publication Management Team:

info@stmjournals.com; Tel : +91 0120-4781211.

Chairman

Mr. Puneet Mehrotra

Managing Director STM Journals, Consortium eLearning Network Pvt. Ltd.(CELNET)

Noida ,India

Group Managing Editor Dr. Archana Mehrotra

DirectorCELNET, Delhi, India

Puneet Pandeya

ManagerMonika Malhotra

Assistant Manager

Assistant Editors

Aditya Sanyal

Himani Garg

Himani Pandey

Publication Management Team

Internal Members

External Members

Dr. Bimlesh Lochab

Industrial Tribology Machine Dynamics & Maintenance

Engineering Centre (ITMMEC)

Indian Institute of Technology Delhi, India.

Prof. S. Ramaprabhu

Alternative Energy Technology Laboratory,

Department of Physics,

Indian Institute of Technology, Chennai, India.

Dr. Rajiv Prakash

School of Materials Science and Technology,

Institute of Technology, Banaras Hindu University,

Varanasi, India.

Dr. Rakesh Kumar

Assistant Professor, Department of

Applied Chemistry, BIT Mesra,

Patna, India.

Associate Editors

Gargi Asha Jha

Nupur Anand

Priyanka Aswal

Sona Chahal

STM Journal (s) Advisory Board

Dr. Ashish RunthalaLecturer, Biological Sciences Group,

Birla Institute of Technology & Science, Pilani Rajasthan, India.

Dr. Baldev RajDistinguished Scientist & Director,

Indira Gandhi Centre for Atomic Research

(ICGAR)Kalpakkam, India.

Dr. Baskar KaliyamoorthyAssociate Professor, Department

of Civil Engineering National Institute of Technology Trichy, India.

Prof. Bankim Chandra RayProfessor and Head, Department of

Metallurgical and Materials Engineering National Institute of Technology,

Rourkela, India.

Prof.D. N. Rao Professor, Department of Biochemistry,

AIIMS, New Delhi, India.

Prof. Jugal KishoreProfessor, Department of Community

Medicine, Maulana Azad Medical College, New Delhi, India.

Dr. Pankaj PoddarScientist, Physical & Materials ChemistryDivision, National Chemical Laboratory,

Pune, India.

Dr. Hardev Singh VirkProfessor Emeritus, Eternal

University, Baru Sahib, India.

Dr. Nandini Chatterjee SinghAssociate Professor,

National Brain Research Centre, Manesar, India.

Dr. Shankargouda PatilAsst. Prof., Department of Oral

Pathology, KLE Society's Institute of Dental Sciences, Bangalore, India.

Prof. Subash Chandra MishraProfessor, Metallurgical & Materials

Engineering Department, NIT, Rourkela, India.

Prof. Yuwaraj Marotrao GhugalProfessor and Head Department, Govt.College of Engineering Station Road,

Osmanpura, Aurangabad, India.

Prof. Sundara RamaprabhuProfessor, Department of Physics

Indian Institute of Technology Madras, India.

Dr. Shrikant Balkisan DhootHead Research & Development,

Nurture Earth R&D Pvt LtdMIT Campus, Beed bypass road,

Aurangabad, India.

Dr. Rakesh KumarAssistant Professor,

Department of Applied Chemistry, BIT Mesra, Patna, India.

Dr. Priyavrat TharejaHead, Materials and Metallurgical

Engineering department, PEC University of Technology,

Chandigarh, India.

STM Journal (s) Advisory Board

Editorial Board

Dr. Ajai Kumar pandey Kayachikitsa ,Institute of Medical Sciences Banaras Hindu Universty

Varanasi.

Amiya Nand Dev GoswamiDean, Department of Homoeopathy

Rajasthan Vidyapeeth University.

Dr. Dominic DiasMember of Central Council of

Homoeopathy,Ministry of Health & Family Welfare, Government of India.

I take the privilege to present the print version for the Volume 1 Issue (1) of Research & Reviews: A

Journal of Unani, Siddha and Homeopathy. The intension of RRJOUSH is to create an atmosphere

that stimulates creativeness, research and growth in the area of Unani, Siddha and Homeopathy.

The development and growth of the mankind is the consequence of brilliant Research done by

eminent Scientists and Engineers in every field. RRJOUSH provides an outlet for Research findings

and reviews in areas of Unani, Siddha and Homeopathy found to be relevant for National and

International recent developments & research initiative.

The aim and scope of the Journal is to provide an academic medium and an important reference for

the advancement and dissemination of Research results that support high level learning, teaching and

research in the domain of Unani, Siddha and Homeopathy.

Finally, and Authors for their continued support and invaluable contributions and suggestions in the

form of authoring I express my sincere gratitude and thanks to our Editorial/ Reviewer board write

ups/ reviewing and providing constructive comments for the advancement of the journals. With

regards to their due continuous support and co-operation, we have been able to publish quality

Research/Reviews findings for our customers base.

I hope you will enjoy reading this issue and we welcome your feedback on any aspect of the Journal.

Dr. Archana Mehrotra

Director

STM Journals

Director's Desk

STM JOURNALS

1. A Novel Technique for Stability Testing of Alliin and Sennosides in Unani Formulations Ghosh A, Shreedhara CS, Shenoy G, Shetty R, Kumar VS, Sanghai DB 1

2. Contraceptive Knowledge, Attitude and Practice among Newly Married Couples Sherwani AMK, Shabnam Ansari, Itrat Malik 6

3. Effect of Wet Cupping (Hijamat Bil Shurt) in the Management of Secondary Amenorrhea (Ehtebas Tams Sanwi)Parveen R, Shameem 12

4. Preliminary Analytical Study of Parangipattai Rasayanam (PRM) – A Siddha Polyherbal FormulationVithyapathi Velmurugan, A. Muthuvelu, K. Manickavasakam 20

5. Prevalence of Dysmenorrhea in Different Age Groups K. Tabassum 23

6. Primary Dysmenorrhea: A Review with Special Reference to Unani Concepts Hina Rehman, Wajeeha Begum, Humyra Tabasum, Farzana Anjum 29

7. Seasonal Changes and Human Health: A Unani Perspective Malik Itrat, Arshad Jamal, Javed A. Khan, M. A. Siddiqui 38

ContentsResearch &Reviews : A Journal of Unani, Siddha and Homeopathy

RRJoUSH (2014)© STM Journals 2014. All Rights Reserved

Research &Reviews : A Journal of Unani, Siddha and Homeopathy

Volume 1, Issue 1

www.stmjournals.com

A Novel Technique for Stability Testing of Alliin and

Sennosides in Unani Formulations

Ghosh A2, Shreedhara CS

1*, Shenoy G

1, Shetty R

2, Kumar VS

1, Sanghai DB

1

1Department of Pharmacognosy, Manipal College of Pharmaceutical Sciences, Manipal-576104,

Karnataka, India 2Manipal Acunova, Manipal-576104, Karnataka, India

Abstract Unani system of medicines is a science which deals with the preventive and promotive aspects of health of human beings and health problems that arise due to factors like

ecological and/or environmental, which include humours categorized as blood, phlegm, yellow bile and black bile, and different biological fluids circulating in various vessels of

the body. There is significant mandate in drug testing for a specific and precise

analytical method for the identification of Alliin and Sennosides in various Unani formulations. A novel technique which combines high performance liquid

chromatography and mass spectrometry (LC-MS/MS) will provide unequivocal thumbprint information for estimation of Alliin and Sennosides in Unani formulations.

The objective of the current study is to develop an efficient, simple, cost-effective and

steady high-performance liquid chromatography method for the quantification of Alliin and Sennosides in Unani formulations and helps in stability testing of these compounds.

The separation of the compounds was achieved in C18 column and positive

(Alliin)/negative (Sennosides) ion mode was used for detection in ESI-MS detection.

Keywords: Alliin, imipramine, sennosides, hydrochlorothiazide, LC-MS/MS

RRJoUSH (2014) © STM Journals 2014. All Rights Reserved

Research &Reviews : A Journal of Unani, Siddha and Homeopathy

Volume 1, Issue 1

www.stmjournals.com

Contraceptive Knowledge, Attitude and Practice among

Newly Married Couples

Sherwani AMK1, Shabnam Ansari

2, Itrat Malik

1*

1National institute of Unani medicine, Bangalore, India

2Government Medical officer, Chattisgarh, India

Abstract The objective of this study was to assess the knowledge, attitude regarding family

planning and the practice of contraceptives among newly married couples attending

NIUM hospital. This study was cross sectional and observational. Total 150 newly

married women from the day of marriage to five-year span, visiting Screening Unit and

Family Planning Unit attached with the OPD of Gynecology and Obstetrics of National Institute of Unani Medicine Hospital, Bangalore, were interviewed. Their knowledge,

attitude and practice on contraceptives were evaluated with the help of a pretested and semi-structured questionnaire. Descriptive analysis was conducted to describe the results

in percentages. Out of 150 interviewed couples, 31 (20.67%) women had low knowledge

index level, 79 (52.67%) had medium knowledge index level, and 40 (26.67%) had high knowledge index level. The media provided information of contraceptives in 77 out of 150

women, while 55 women obtained the knowledge of contraceptives from family

members/relatives. Regarding the usage of contraceptive methods, only 58 of the respondents were using some sort of contraception. Out of 58 contraceptive users, 17

were pill users, 23 Cu-T users, 16 condom users and two were using other methods. No one in this group practiced female sterilization. 92 couples had not ever practiced any

method of contraception. Positive attitude towards contraception was shown by 122

(81.33%) women, while 28 (18.7%) women had an attitude of disapproval towards contraception. In the present study, there was a low contraceptive use among newly

married women despite good knowledge. Motivation through media and family members

can help to achieve positive attitude of newly married couples for effective use of contraceptives.

Keywords: Knowledge, practice, contraception, newly married couples

RRJoUSH (2014)© STM Journals 2014. All Rights Reserved

Research &Reviews : A Journal of Unani, Siddha and Homeopathy

Volume 1, Issue 1

www.stmjournals.com

Effect of Wet Cupping (Hijamat Bil Shurt) in the

Management of Secondary Amenorrhea (Ehtebas

Tams Sanwi)

Parveen R*, Shameem I Ilmul Qabalat wa Amraze Niswan, National Institute of Unani Medicine, Bangalore, India

Abstract Secondary amenorrhea is a common distressing symptom caused by a multitude of

pathological processes and its incidence due to polycystic ovarian syndrome is 15–30%. The objective of the study was to evaluate the efficacy of wet cupping in patients with

secondary amenorrhea. A randomized open-labeled study was carried out at Gynecology OPD of the Institute’s Hospital in Bangalore. Forty patients with secondary amenorrhea

due to polycystic ovarian disease, obesity, hyperprolactinemia in the age group of 18–

40 years were included and randomly allocated into two groups (A and B), comprising of 20 patients in each group for interventions. For both the groups, one tablet of habbe

mudir consisting of Crocus sativus (Zafran), ferrous sulphate (Heera kasees) each 1 g

and Aloe barbadensis (Elwa) 2 g was administered orally with butter milk thrice daily, five days before the expected date of menstruation for three consecutive cycles. In group

A, wet cupping was applied over the calf muscles simultaneously on first and fourth day of administration of habbe mudir. Two medium-sized cups were applied for 5–10 min

over the calf muscles and drawn blood was measured. Primary outcome measures were

restoration of normal menstruation and changes in body mass index, secondary outcome

measures were changes in pelvic scan and hormonal profile; were assessed for

improvement. Results were analyzed statistically by using student ‘t’ test, Chi-square and

Fisher exact test. The inter-group comparison showed that group A was more effective than compared to group B in restoration of normal menstruation and changes in

hormonal profile. Wet cupping was more effective than compared to habbe mudir in inducing menstruation. Hence, it can be recommended as an alternate therapy in

secondary amenorrhea

Keywords: Secondary amenorrhea, wet cupping, habbe mudir

RRJoUSH(2014)© STM Journals 2014. All Rights Reserved

Research &Reviews : A Journal of Unani, Siddha and Homeopathy

Volume 1, Issue 1

www.stmjournals.com

Preliminary Analytical Study of Parangipattai Rasayanam

(PRM) – A Siddha Polyherbal Formulation

Vithyapathi Velmurugan1,2

*, A. Muthuvelu2, K. Manickavasakam

2

1A.T.S.V.S Siddha Medical College, Munchirai, India

2National Institute of Siddha, Chennai, India

Abstract Parangipattai Rasayanam is a purely herbal product used commonly for the management

of Vaatha diseases (anti-inflammatory and analgesic activity), skin diseases, etc. The

Parangipattai Rasayanam is an orally administrable pharmaceutical drug which is a

combination of 28 ingredients namely Parangipattai (Smilax china, Linn), Kodiveli (Plumbago zeylanica), Amukaraa (Withania somnifera, Linn), Milagu (Piper nigrum,

Linn), Thipili (Piper longum, Linn), Omam (Carum capticum benth and Hook),

Kurosaaniomam (Hyoscyamus niger, Linn), etc. Lack of standardization of polyherbal formulations creates difficulty in validating the efficacy and maintaining quality of the

product. Hence, an attempt has been made to study Parangipattai Rasayanam by analyzing through qualitative analysis. The data evolved in the present study will help

maintain the quality of the formulation.

Keywords: Parangipattai Rasayanam, qualitative analysis.

RRJoUSH (2014)© STM Journals 2014. All Rights Reserved

Research &Reviews : A Journal of Unani, Siddha and Homeopathy

Volume 1, Issue 1

www.stmjournals.com

Prevalence of Dysmenorrhea in Different Age Groups

K. Tabassum* National Institute of Unani Medicine, Bangalore, India

Abstract Dysmenorrhea (painful menstruation) is one of the major gynecological problems,

encountered in women of reproductive age. It accounts for more than 1/4th gynaec

patients’ visits to the gynecologist. The pain may be spasmodic or congestive type and occurs in lower abdomen, low back or in the thighs. It starts one or two days before onset

of menstruation and continues for two days with same intensity or sometimes the pain

decreases with the onset of menstruation. Among the forms of dysmenorrhea, the most

frequent form occurs in general is spasmodic type in which the pain is colicky in nature

and is felt mainly in the hypogastric region and may radiate to the thighs. The present study was designed and conducted to estimate the prevalence of dysmenorrhea in

gynecological patients who attended OPD of Department of Ilmul Qabalat wa Amraze

Niswan, National Institute of Unani Medicine, Bangalore, during the second half of the year 2013. Out of 824 gynecological cases, 117 patients were of dysmenorrhea. Among

them most patients were of reproductive age between 12 and 47 years, both unmarried and married. A detailed history was taken to sort out the cases according to the type,

origin of pain and associated symptoms. For this study, the hospital data were taken for

finding the prevalence of dysmenorrhea in the target group.

Keywords: Gynecological problem, observation, dysmenorrhea and prevalence

RRJoUSH (2014) © STM Journals 2014. All Rights Reserved

Research &Reviews : A Journal of Unani, Siddha and Homeopathy

Volume 1, Issue 1

www.stmjournals.com

Primary Dysmenorrhea: A Review with Special Reference

to Unani Concepts

Hina Rehman*, Wajeeha Begum, Humyra Tabasum, Farzana Anjum National Institute of Unani medicine, Bangalore, India

Abstract Dysmenorrhea is potentially the most common and most underdiagnosed gynecologic condition. It is characterized by crampy lower abdominal pain radiating to back and

thigh. Nausea, vomiting, headache and diarrhea are frequent accompanying symptoms.

An excess or imbalance of prostaglandins, vasopressin, and chemical substances derived

from phospholipids play an important role in generating primary dysmenorrhea

symptoms, although exact pathology is still difficult to understand. An estimated 10–30% of all working or studying women lose 1–3 working days per month due to dysmenorrhea.

Despite the high prevalence, most of the girls are under-treated because of common societal beliefs regarding a lack of effective treatment and expectations about the burden

of menstruation. Although conventional medicines are the initial first line therapy, some

women may not always find them effective or acceptable due to intolerance or contraindications. A number of alternative and complementary therapies are available;

Unani system of medicine is one of them. The condition is clearly described by various

legendary Unani physicians as Darde Rehm centuries earlier. The focus of this review article is on Unani concept and modern aspect of primary dysmenorrhea.

Keywords: Primary dysmenorrhea, Unani system, prostaglandins, Darde Rehm

RRJOUSH (2014)© STM Journals 2014. All Rights Reserved

Research & Reviews: A Journal of Unani, Siddha and Homeopathy Volume 1, Issue 1

www.stmjournals.com

Seasonal Changes and Human Health: A Unani

Perspective

Malik Itrat*, Arshad Jamal, Javed A. Khan, M. A. Siddiqui

National Institute of Unani Medicine, Bangalore, India

Abstract Influence of seasonal variations on human health has been a subject of considerable

interest in epidemiological studies and observed for centuries. The Unani scholars have

given a vivid description about seasonal changes, diseases peculiar to each season and guidelines for maintaining health in a positive and individualized manner in different

seasons under the heading of Tadabir-i-Mausam. In every season, air changes to a new

temperament. The effect of the changing seasons is not due to the season itself, but to the quality which is changed along with them, for this exerts a marked effect upon the states

of the body. As the seasonal changes produce their own characteristic diseases, it is necessary that people should be well acquainted with the prevailing environmental

conditions and the necessary measures required to meets them.

Keywords: Seasonal variations, human health, Tadabir-i-Mausam, seasonal diseases