research support (siemens) consultant (hologics) speaker fees … · 2011. 8. 12. · 2011 aapm...

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2011 AAPM (Vancouver, BC) 1 Estimating Patient Specific Doses/ Risks in Fluoroscopy Walter Huda Radiology and Radiological Science MUSC Charleston, SC Financial Disclosures Research Support (Siemens) Consultant (Hologics) Speaker Fees (Carestream) Book Royalties (LWW, MPP) President (Huda Physics in Medicine) PURPOSE Patient Doses (Risks) of Interest Skin Doses Embryo Doses Organ Doses (?Effective Dose?)

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Page 1: Research Support (Siemens) Consultant (Hologics) Speaker Fees … · 2011. 8. 12. · 2011 AAPM (Vancouver, BC) 3 Within each type of CT study, effective dose varied significantly

2011 AAPM (Vancouver, BC) 1

Estimating Patient Specific

Doses/ Risks in Fluoroscopy

Walter Huda

Radiology and Radiological Science

MUSC Charleston, SC

Financial Disclosures

Research Support (Siemens)

Consultant (Hologics)

Speaker Fees (Carestream)

Book Royalties (LWW, MPP)

President (Huda Physics in

Medicine)

PURPOSE Patient Doses (Risks) of Interest

Skin Doses

Embryo Doses

Organ Doses

(?Effective Dose?)

Page 2: Research Support (Siemens) Consultant (Hologics) Speaker Fees … · 2011. 8. 12. · 2011 AAPM (Vancouver, BC) 3 Within each type of CT study, effective dose varied significantly

2011 AAPM (Vancouver, BC) 2

Are exams indicated? Benefits > radiation risks

Barium Enema

Effective Dose ~ 5 to 15 mSv

Age (Years)

20 30 40 50 60 70 80

% p

er

10

0 m

Sv

0.0

0.5

1.0

1.5

2.0

M ales C ancer Incidence

Fem ale C ancer Incidence

BEIR VII Data

Risk varies by ~ x7 with age

Page 3: Research Support (Siemens) Consultant (Hologics) Speaker Fees … · 2011. 8. 12. · 2011 AAPM (Vancouver, BC) 3 Within each type of CT study, effective dose varied significantly

2011 AAPM (Vancouver, BC) 3

Within each type of CT study, effective dose

varied significantly within and across

institutions, with a mean 13-fold variation

between the highest and lowest dose for each

study type

Arch. Intern Med. 169 (2009) 2078

(Any) Patient Risk Uncertain

x 10? x 100?

FLUOROSCOPY DOSES & RISKS PCXMC

Page 4: Research Support (Siemens) Consultant (Hologics) Speaker Fees … · 2011. 8. 12. · 2011 AAPM (Vancouver, BC) 3 Within each type of CT study, effective dose varied significantly

2011 AAPM (Vancouver, BC) 4

FID

Focal Spot

Image Size:

25 x 25 cm

FID:

100 cm

KAP:

10 Gy-cm2

PA Projection

PCXMC Phantom

PCXMC “Output”

Organ Dose (mGy)

Effective Dose E (mSv)

PCXMC “Input”

Kerma Area Product (Gy-cm2)

(+ Beam Quality)

Organ Dose Cancer Incidence Risk

Page 5: Research Support (Siemens) Consultant (Hologics) Speaker Fees … · 2011. 8. 12. · 2011 AAPM (Vancouver, BC) 3 Within each type of CT study, effective dose varied significantly

2011 AAPM (Vancouver, BC) 5

Vary patient “size” (PCXMC) RESULTS

Cancer RiskDifferent Beam Qualities

(kV/filtration)

Page 6: Research Support (Siemens) Consultant (Hologics) Speaker Fees … · 2011. 8. 12. · 2011 AAPM (Vancouver, BC) 3 Within each type of CT study, effective dose varied significantly

2011 AAPM (Vancouver, BC) 6

Variable Beam Quality Variable Beam Quality

Cancer RiskPatient Size

Page 7: Research Support (Siemens) Consultant (Hologics) Speaker Fees … · 2011. 8. 12. · 2011 AAPM (Vancouver, BC) 3 Within each type of CT study, effective dose varied significantly

2011 AAPM (Vancouver, BC) 7

70 kg

Patient Size

Nominal E

~

E70 x (70 / W)

70 kg W kg

70 kg

E = organs Di x wi

Page 8: Research Support (Siemens) Consultant (Hologics) Speaker Fees … · 2011. 8. 12. · 2011 AAPM (Vancouver, BC) 3 Within each type of CT study, effective dose varied significantly

2011 AAPM (Vancouver, BC) 8

Patient Radiation (E)

vs

Natural Background Regulatory Limits

Other Procedures

Patient Specific Risks OBTAINABLE

USEFUL in Clinical Practice?

Educational Tool

Page 9: Research Support (Siemens) Consultant (Hologics) Speaker Fees … · 2011. 8. 12. · 2011 AAPM (Vancouver, BC) 3 Within each type of CT study, effective dose varied significantly

2011 AAPM (Vancouver, BC) 9

Radiation-Related Cancer Risks

in a Clinical Patient Population

Undergoing Cardiac CT

Huda et al;

AJR 196 (2011) W159-65

x 10 Range in Patient Risk

Page 10: Research Support (Siemens) Consultant (Hologics) Speaker Fees … · 2011. 8. 12. · 2011 AAPM (Vancouver, BC) 3 Within each type of CT study, effective dose varied significantly

2011 AAPM (Vancouver, BC) 10

Benefit versus Risk Justification + Optimization

Tube current modulation

(AP projection zero)

Page 11: Research Support (Siemens) Consultant (Hologics) Speaker Fees … · 2011. 8. 12. · 2011 AAPM (Vancouver, BC) 3 Within each type of CT study, effective dose varied significantly

2011 AAPM (Vancouver, BC) 11

CONCLUSION Estimate Effective Dose (E)

Adjust E for patient size Patient Specific Radiation Risk

Remember “risk caveats”

Page 12: Research Support (Siemens) Consultant (Hologics) Speaker Fees … · 2011. 8. 12. · 2011 AAPM (Vancouver, BC) 3 Within each type of CT study, effective dose varied significantly

2011 AAPM (Vancouver, BC) 12

1 in 10,000 risk for 40 y.o. ♂

1 year 0.5 mSv

Differences in life expectancy

of “patients” and normal population

Risk Uncertainties

The author acknowledges

Dennise Magill for her

assistance

Page 13: Research Support (Siemens) Consultant (Hologics) Speaker Fees … · 2011. 8. 12. · 2011 AAPM (Vancouver, BC) 3 Within each type of CT study, effective dose varied significantly

2011 AAPM (Vancouver, BC) 13

Thank You!

[email protected]