Reversal From Neuromuscular Blockade: Improving Patient Safety and Surgical Outcomes

Goals

Overview

Defining Adequate Neuromuscular Recovery

Defining Residual Blockade

Incidence of Residual Blockade

Incidence of Residual Blockade (cont)

Neuromuscular Monitoring and Postoperative Residual Curarization Meta-analysis

Conclusion of Naguib and Colleagues Meta-analysis

Clinical Consequences of Residual Block

Clinical Consequences: Volunteer Studies

Clinical Consequences: Clinical Studies

Clinical Consequences: Clinical Studies (cont)

Patient Risk Factors For Residual Blockadea

Factors Contributing to Residual Blockade

Factors Contributing to Residual Blockade (cont)

Factors Contributing to Residual Blockade (cont)

Sugammadex: A Potential Alternative

Sugammadex: Importance of Monitoring and Appropriate Dosing

Potential Benefits of Sugammadex

Mechanism of Action

Strategies for Avoiding Postoperative Residual Block

Strategies for Avoiding Postoperative Residual Block (cont)

Baillard and Colleagues Study

Baillard et Study Follow-up

Abbreviations

References

References (cont)

References (cont)

References (cont)

References (cont)

References (cont)