reverse federation - amazon s3 · 2019-07-27 · interface strategies • hl7 –2.x –web api/hl7...
TRANSCRIPT
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reverse federationboldly going where no interface has gone beforekeluo yao m.d.
University of Michigan
Stardate 72809.9
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DISCLOSURE
In the past 12 months, I have not had any significant financial
interest or other relationship with the manufacturers of the
products or providers of the services that will be discussed in my
presentation.
Any commercial products or vendors mentioned in this
presentation are for presentation purposes only.
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Captain’s log, stardate 72809.9
• Jim, I am a doctor, not a
secretary. I can’t spend all
my time and go after every
single piece of information I
need to do my job! Cant
the federation do something
about it?
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van der Waaij LA, van Dullemen HM, Porte RJ. Cyst fluid analysis in the differential diagnosis of
pancreatic cystic lesions: a pooled analysis. Gastrointest Endosc. 2005;62:383–389
Pitman, Martha Bishop, and Lester James Layfield. The Papanicolaou Society of Cytopathology System for Reporting Pancreaticobiliary Cytology: Definitions, Criteria and Explanatory Notes. Springer, 2015.
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Keren, David. Protein electrophoresis in clinical diagnosis. CRC Press, 2003.
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Borrowed with permission from Paul J. Chang, M.D
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Data Granularity and Standardization
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Chekov comments
• But captain, what is the issue
here, doesn't the Federation
allow us access to clinical
information through a
unified interface in the EHR?
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Why Do We Have the Federation?
• $48 billion U.S. Investment.
• Data stored on electronically can be used to:
– Manage patient care
– Maximization of revenue
– Enable precision medicine through research from the molecular to
population scale
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The Three approaches
Source: https://www.greenhousedata.com/blog/manage-data-across-your-clouds-with-data-federation-data-hubs-or-data-lakes
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The Federated Approach
• Uses a software abstraction
layer to combine various
database sources into a
single view
• AKA virtualized database
architecture
• The source data is not
moved or copied
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The Data Lake Approach
• Move all data into a single location
• Structured or unstructured data
• Indexing…what is that?
• Stay tuned to Dr. William’s lecture “Data Lakes, Warehouses and Marts, Oh My!”
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The Data Hub Approach
• Data is moved/copied and
indexed to a central hub
• Data can be easily queried
• Highest overhead for
interoperability
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Why do a Federated Approach?
• No need to move or copy data into a central repository
– Maintain single source of truth
• Real time access of data
• Maybe the only option to realistically to combine
heterogeneous data from multiple sources that changes
frequently.
– Which can be institution(s), service(s), and data type(s)
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http://www.tefg.com/Structure/support/default.html
Parent
Child
Child
Child
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Single Source of Truth
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Why do a Federated Approach?
• No need to move or copy data into a central repository
– Maintain single source of truth
• Real time access of data
• Maybe the only option to realistically to combine
heterogeneous data from multiple sources that changes
frequently.
– Which can be institution(s), service(s), and data type(s)
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• Jim, I am a doctor, not an
archaeologist. I need the
federation to give me real
time clinical information.
• Or this might happen…
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Why do a Federated Approach?
• No need to move or copy data into a central repository
– Maintain single source of truth
• Real time access of data
• Maybe the only option to realistically to combine
heterogeneous data from multiple sources that
changes frequently.
– Which can be institution(s), service(s), and data type(s)
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Federated Approach is Also Excellent for…
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Source: https://mehi.masstech.org/sites/mehi/files/documents/MeHI_2010_HIT_Plan.pdf
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Source: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4371446/pdf/egems1060.pdf
Purist approach is not
necessary
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Source: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4371446/pdf/egems1060.pdf
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Captain, we are receiving a transmission
• The message is from the
Klingons…I am decoding it
now.
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• The Klingons want to
reverse their hostility
towards the federation
and I need to study their
anatomy to save
Chancellor Gorkon to
achieve peace!
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Spock speaks
• Captain, the federation
rules forbade dealing with
outlaws and getting
involved in the politics of
other cultures
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Kirk speaks
• We have reversed time and rank before to save people; we will reverse this federation rule to save one more life and achieve peace. Mr. Spock, can we communicate with the Klingons through the federation with our intent?
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Spock speaks
• In theory we could interface
with the federation
through a highly agile SOA
to get to the Klingons.
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Kirk speaks
• Excellent Mr. Spock. Take us
there Mr. Sulu.
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http://www.tefg.com/Structure/support/default.html
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http://www.tefg.com/Structure/support/default.html
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Reverse Federation
Access of a federated repository in a direction opposite to
the normally considered primary/subordinate linkage
- Ulysses Gregory John Balis, M.D.
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What about interoperability?
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Web 2.0
• User generated content
• Ease of use
• Participatory culture
• Interoperability
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Web 2.0
• User generated content
• Ease of use
• Participatory culture
• Interoperability
– JavaScript framework
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Service-oriented architecture (SOA)
• An open, agile, extensible, federated, compostable
architecture comprised of autonomous, Quality of Service
(QoS)-capable, vendor diverse, interoperable, discoverable,
and potentially reusable services, implemented as Web
services
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Service-oriented architecture (SOA)
• An open, agile, extensible, federated, compostable
architecture comprised of autonomous, Quality of Service
(QoS)-capable, vendor diverse, interoperable, discoverable,
and potentially reusable services, implemented as Web
services
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SOA, the Approach
• SOA = architecture/concept
• Web Service = implementation strategy
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Interface Strategies
• HL7
– 2.x
– Web API/HL7 FHIR
• Data Repository / Data Warehouse
• Middleware/Interface Engine/Enterprise Service Bus (ESB)
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Order
Interface
Figure from: A. Carter, MD
Result
Interface
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HL7 2.X
PID|||PATID1234 5̂^M11^^AN||JONES^WILLIAM^A^III||19610615|M||2106-3|677 DELAWARE
EVN|A01|198808181123
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The Data Hub Approach
• Data is moved/copied and
indexed to a central hub
• Data can be easily queried
• Highest overhead for
interoperability
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HL7 2.X
Source: https://corepointhealth.com/thank-you/future-interoperability-web-apis-fhir/
AKA middleware
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Enterprise Service Bus
• Data transformation
– XML
– Binary
– Text
– CSV
– Swift
– HL7
– CDA
– DICOM
– EDI
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Enterprise Service Bus
• Protocol Conversion– TCP/IP
– HTTP– MLLP
– Web service (SOAP/REST)
– Database– FTP/SFTP
– Email– File System
– Message Queue (JMS, MSMQ, Websphere MQ and etc.)
– DICOM
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Enterprise Service Bus
• Data Routing
• Data enhancement
• Data administration/monitoring
• Security
• Scalability and cost effective
• SOA friendly
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Borrowed with permission from Paul J. Chang, M.D
Clinical Context Lookup Tool – University of Chicago Radiology
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Borrowed with permission from Paul J. Chang, M.D
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Borrowed with permission from Paul J. Chang, M.D
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Source: https://mehi.masstech.org/sites/mehi/files/documents/MeHI_2010_HIT_Plan.pdf
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Web 2.0
• User generated content
• Ease of use
• Participatory culture
• Interoperability
– JavaScript framework
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Web Application Programming Interface (API)
• HTTP
– Representational state transfer (REST)
– Simple Object Access Protocol (SOAP)
• Payload data
– Extensive Markup Language (XML)
– JavaScript Object Notation (JSON)
– HyperText Markup Language (HTML)
• Websocket
– Industry lag
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Web API
• Fast Healthcare Interoperability Resources (FHIR)
• Modeled after web application programming interface (API)
REST
JSON
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Keren, David. Protein electrophoresis in clinical diagnosis. CRC Press, 2003.
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<div class='clinical-note-section '>
<span class='clinical-note-section-action displayonly' style='display:none; text-decoration:none;'>
<a tabindex='0' title=''>Expand All</a> <a tabindex='0' title=''>Collapse All</a>
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<table class='rz_y'><tr class='rz_w'>
<td class='rz_z'>
<!--EPICS-->MULTIDISCIPLINARY CHRONIC KIDNEY DISEASE CLINIC – CLINICAL PHARMACIST NOTE
<br>
<br>Encounter Date: 1/2/2019<br>Supervising Physician: Dr. ############
<br>
<br>Subjective:
<br>########## is a 67 y.o. male seen for Chronic kidney disease (CKD) Stage III and medication management.
<br><br>Hypertension/Volume
<br>Regarding hypertension, he is currently taking carvedilol 6.25 mg tw ice daily, eplerenone 50 mg daily, Lasix (brand name) 40 mg tw ice daily, hydralazine 10 mg tw ice daily, and metolazone 5 mg on Mon/Weds/Fri. He sees an outside cardiologist. Patient does
not take medications that may w orsen hypertension. He states he checks home BP infrequently as he goes to the doctor 3-4 times a month and readings have alw ays been on the low side. He reports that generic furosemide resulted in a previous hospitalization and
is only able to take brand name medications. He denies any light-headedness, chest pain.
<br><br>Hyperlipidemia/CV Risk
<br>Regarding hyperlipidemia, he is currently taking atorvastatin 40 mg daily. Patient denies muscle aches or pains that are changed from baseline (chronic back pain).
<br>
<br>Diabetes
<br>Regarding diabetes, he is currently taking insulin glargine (Lantus) 35 units in the morning and insulin aspart three times a day using a sliding scale. He reports 2-3 episodes of symptomatic hypoglycemia in he past month. They all occured overnight, and he is w oken up due to cold sw eats, dizziness. Hypoglycemia is treated by eating a peanut butter & jelly sandw ich. He checks home blood sugars four times daily and recalls readings 99-114 in the mornings w ith pre-meal readings in the 100-200s. He states the 200s
are infrequent.
<br>
<br>Lifestyle
<br>Not discussed in detail today.<br>
<br>Medication Management
<br>Patient reports excellent adherence to prescribed medications w ith missed doses occurring rarely ever. Patient does use a pill box w hen on vacation. Otherw ise, he uses a reminder method of storing his pill bottles above the refrigerator in a cabinet. Insurance is
the primary source of paying for medications w ith some diff iculty affording medications reported at this time (~$200-400/month). Specif ically, his insulin ($150/3 months) and some of his brand name medications. He is not interested in 30-day supplies of medications
as he prefers the convenience (fewer trips to the pharmacy) of 90-day supplies.<br>
<br>Current Medication List:
<br>Outpatient Medications Prior to Visit
<br>Medication Sig Dispense Refill
<br>• amiodarone (CORDARONE, PACERONE) 200 mg tablet Take 200 mg by mouth tw o times daily. <br>• apixaban (ELIQUIS) 5 mg tablet Take 5 mg by mouth tw o times daily.
<br>• ascorbic acid (VITAMIN C) 1,000 mg Tablet Take 1 Tablet by mouth Daily tablet
<br>• aspirin (ECOTRIN LOW STRENGTH) 81 mg delayed release tablet Take 1 Tablet, Delayed Release (E.C.) by mouth Daily
<br>• atorvastatin (LIPITOR) 40 mg tablet Take 40 mg by mouth at bedtime.
<br>• carvedilol (COREG) 6.25 mg tablet Take 6.25 mg by mouth tw o times daily. 0 <br>• cholecalciferol (VITAMIN D3) 400 unit capsule Take 1 Capsule by mouth Daily capsule
<br>• digoxin 62.5 mcg Tablet Take 62.5 mcg by mouth every other day.
<br>• eplerenone (INSPRA) 25 mg tablet Take 2 tablets (50 mg) by mouth once daily. 180 tablet 4
<br>• f luticasone (FLONASE) 50 mcg/actuation nasal spray Spray 1 spray into the nose tw o times daily.
<br>• furosemide (LASIX) 40 mg tablet Take 1 Tablet by mouth Daily (Patient taking differently: Take 1 tablet by mouth every morning. ) 90 tablet 3 <br>• hydrALAZINE(APRESOLINE) 10 mg tablet Take 10 mg by mouth tw o times daily.
<br>• insulin aspart (NovoLOG) 100 unit/mL injection Inject into the skin 3 times daily w ith meals. Use as directed per sliding scale. Maximum 40units daily
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https://www.healthit.gov/sites/default/files/c-cda_and_meaningfulusecertification.pdf
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<!DOCTYPE html>
<html lang="en">
<head>
<meta charset="utf-8">
<title>title</title><link rel="stylesheet" href="style.css">
<script src="script.js"></script>
</head>
<body>
<!-- page content --></body>
</html>
A Barebones HTML page
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Summary
• Federated database architecture
– A popular strategy for healthcare information integration/exchange in addition to data lake and data hub
– Unified view for child/subordinate database(s)
– Real time data access
– Single source of truth
– Source data is not copied or moved
• Reverse Federation– Access of a federated repository
in a direction opposite to the normally considered primary/subordinate linkage
– An information integration/exchange strategy for SOA
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Tuesday, May 7, 8:30 am in Grand Ballroom 1
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Acknowledgement
• University of Michigan
– Ulysses Balis MD
– David McClintock MD
– Christopher Williams MD
• University of Chicago
– Paul Chang MD
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Questions?
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References
• Mandl, Kenneth D., and Isaac S. Kohane. "Federalist principles for healthcare data networks." Nature biotechnology 33.4 (2015): 360.
• https://www.himss.org/library/interoperability-health-information-exchange/environmental-scan/care-everywhere
• https://revcycleintelligence.com/features/how-hospital-merger-and-acquisition-activity-is-changing-healthcare
• https://www.progress.com/blogs/agile-ma-pre-and-post-merger-data-integration-guide
• Loya, Salvador Rodriguez, et al. "Service oriented architecture for clinical decision support: A systematic review and future directions." Journal of medical systems 38.12 (2014): 140.
• https://corepointhealth.com/thank-you/future-interoperability-web-apis-fhir/
• Keren, David. Protein electrophoresis in clinical diagnosis. CRC Press, 2003.
• www.ncbi.nlm.nih.gov/pmc/articles/PMC4371446/pdf/egems1060.pdf