rieger's syndrome description: a genetically determined syndrome of malformations of the...
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Rieger's syndrome
Description:A genetically determined syndrome of malformations of the anterior chamber of the eye and the teeth, combining features of the Axenfeld syndrome with oligodontia. Eye anomalies consist of posterior embryotoxon (an opaque ring at the margin of thecornea), a prominent Schwalbe ring, iris adhesion to the Schwalbe line, hypoplasiaof the anterior stroma of the iris, and occasional glaucoma. Tooth anomalies includeanondontia vera and microdontia.
The Pituitary Gland
www.med.mun.ca/anatomyts/head/pit.htm
Gene Gene product Assay
lacZ β-galactosidase Histochemical test
uidA β-glucuronidase Histochemical test
lux Luciferase Bioluminescence
GFP Green fluorescent protein
Fluorescence
Reporter Gene Assay
PITX2-LACZ Staining of mouse embryo day 11
PITX2: bicoid-related transcription factor
Transgenic Mouse (Tg Mouse)
www.beardedman.net/science/genetics/xeno.html
http://www.collaslab.com/article.php?id=18
Chromatin Immunoprecipitation (ChIP) assays are used to evaluate the association of proteins with specific DNA regions.
The WNT Signaling Pathway
http://atlasgeneticsoncology.org/Deep/WNTSignPathID20042.html