robert scranton© 2008. 5 cardinal signs of inflammation heat redness swelling/ edema pain loss of...
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Robert Scranton© 2008
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5 Cardinal Signs of InflammationHeatRednessSwelling/ EdemaPainLoss of Function
Vascular DilationVascular DilationExudateAfferent InformationA result of the
edema and pain
Caused By?
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InflammationAcute Chronic
Neutrophil
No
Neutrophil
Lymphocytes, monocytes, eosinophils
Yes
Lymphocytes (also macrophages)
Cell type:
Angiogenesis:
Hallmark:
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InflammationMast Cell NeutrophilIgE
Heparin, Histamine & SRS-A
Around small bv, external epithelia
IgG & complement
Primary granules= Lysozyme & myeloperoxidaseSecondary Granules= alkaline phosphataseTertiary Granules= gelatinase
• intravascular
Receptor:
Contents
Location
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Special Neutrophil infoLife span?When dead after
responding to inflammation, they become?
How do neutrophils survive in devascularized tissue?
Explain the process by which they get into the area of inflammation.
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Margination
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Rolling
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Diapedesis
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MacrophageDerived from?Surface receptor
types?Activated
macrophages look ________.
What happens when many macrophages surround large foreign bodies?
Functions
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LymphocytesNuclear/cytoplasmic
ratio?Cell mediated=?Humoral= ?
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EosinophilsPhagocytic activitySurface receptors
for?How does it attack
parasites?Granules, what type?
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=
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BasophilsReceptors forDiscuss slow and fast
granule releaseGranules contain?
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ReconstructionDays?Fibroblasts+
vascular endothelial cells= ?
What are the characteristics of granulation tissue?
What happens after reconstruction?
Primary v. secondary union
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RemodelingTime periodTypical maximal
tensile strength of the CT is?