rsv : respiratory syncytial virus
DESCRIPTION
RSv : Respiratory Syncytial virus. Barbara Woodall. Background. Discovered in 1956 C hildhood illnesses Causes bronchioltitis & pneumonia Age 2 ("Respiratory syncytial virus," 2014). Background. Family: Paramyxovirida Subfamily: Pneumovirinae An enveloped RNA virus - PowerPoint PPT PresentationTRANSCRIPT
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RSV:RESPIRATORY
SYNCYTIAL VIRUS
Barbara Woodall
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BACKGROUND
Discovered in 1956
Childhood illnesses
Causes bronchioltitis & pneumonia
Age 2
("Respiratory syncytial virus," 2014)
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BACKGROUND
Family: Paramyxovirida
Subfamily: Pneumovirinae
An enveloped RNA virus
Strains A and B
("Respiratory syncytial virus," 2014)
1
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TRANSMISSION
Water droplets
Indirect contact
Spreads rapidly among children
Contagious even after 1-3 weeks
(“rsvprotection,” 2013)
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PREVENTION
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PREVENTION
Hand washing
Keeps hands away from face
Avoid contact with people who are sick
Cover coughs and sneezes
Clean and disinfect surfaces
Stay home when sick
("Respiratory syncytial virus," 2014)
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Warm water
Soap
Remove jewelry
Wash for twenty
seconds
HAND WASHING
2
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SYMPTOMS
Illness 4-6 days after exposure
Runny nose and decrease in appetite (2-8 days)
Coughing, sneezing and fever (1-3 days after)
Infants: • Irritability • Decreased activity and breathing
("Respiratory syncytial virus," 2014)
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RED ALERT SIGNS
Non stop coughing or wheezing
Fast or troubled breathing
Fever > 100
Bluish color around mouth or fingernails
Spread-out nostrils and/or caved-in chest
Gasping for breath
(“rsvprotection,” 2013)
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Antigen Detection Test
Suplement Antigen
Testing with cell culture
RT-PCR assay
("Respiratory syncytial
virus," 2014)
DIAGNOSING
3
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TREATMENT
Recovery in 1-2 weeks
May cause Sever lung infections
Some infants may require hospitalization
("Respiratory syncytial virus," 2014)
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HIGH RISK
4
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HIGH RISK
Infants under 6 weeks
Born before 35 weeks
Chronic lung disease
Congenital heart disease
Weekend immune systems ( Anekwe)
(“rsvprotection,” 2013)
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STATISTICS
4,500 deaths a year in the US• Infants 2-6 months
Life-threatening pneumonia• Easily diagnosed as influenza
About 1% of children will require hospitalization
Between 25-40 out of 100 young children show sings of
pneumonia or bronchiolitis ("Respiratory syncytial virus,"
2014)
(Tortora, Case & Case, 2010)
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PREVALENCE
Varies by location (RSVprotection)
Time and severity vary from year to year
Usually occurs during late fall, winter and early spring
("Respiratory syncytial virus," 2014)
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PREVALENCE
5
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NEW DEVELOPMENTS
Immune globulin product has been approved
Protective vaccines being clinically tested
Sever symptoms helped by aerosol
Humanized monoclonal antibody
(Tortora, Case & Case, 2010)
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NEW DEVELOPMENTS
Respiratory illness in older adults ("Respiratory
syncytial virus," 2014)
Palivizumab for high risk children (Anekwe, 2009)
Antivirals with anti-inflammatory therapies
("Respiratory syncytial virus," 2010)
New imaging technique to study RSV living cells
(Toon, 2013)
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SUPER-RESOLUTION OPTICAL IMAGE
6
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PLACES DOING RESEARCH
Arctic Investigation Program ("Respiratory syncytial virus,"
2014)• immunity
National Institute of Allergy and Infectious Diseases
("Respiratory syncytial virus," 2010)• Immunity
National Institute of General Medical Sciences (Toon, 2013)• How it enters• How it Replicates• How many genomes inserted into hosts
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WORKS CITED
Anekwe, Lilian. Government considers immunizing children against RSV. (2009, January 14). Retrieved form
http://www.pulsetoday.co.uk/government-considers-immunising-children-against-rsv/10995958.article#.
UzXevNytg2w
Paving the way for respiratory syncytial virus. ( 2013, September). Retrieved form
http://www.path.org/publications/files/VAC_rsv_fs.pdf
Rsv protection. (2013). Retrieved from https://www.rsvprotection.com/index.html
Respiratory syncytial virus. (2014, April 01). Retrieved from http://www.cdc.gov/rsv/
Respiratory Syncytial Virus. (2010, March 15) Retrieved from
http://www.niaid.nih.gov/topics/rsv/research/pages/researchrole.aspx
Toon, John. (2013, December 30). Imaging Technology Could Unlock Mysteries of a Childhood Disease.
Retrieved form
http://www.news.gatech.edu/2013/12/29/imaging-technology-could-unlock-mysteries-childhood-disease
Tortora, G., Case, C., & Case, C. (2010). Microbiology: An introduction. (10th ed., p. 692). San Francisco:
Pearson Education Inc
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PICTURE CITED
Respiratory syncytial virus RSV. Retrieved fromhttp
://www.bode-science-center.com/center/relevant-pathogens-from-a-z/respiratory
-syncytial-virus.html
Sucher, Peggy. Hand Washing – The #1 Deterrent to the Spread of
Contaminants. (2011, November 7) Retrieved form http
://tattooroadtrip.com/wp-content/uploads/2011/10/Handwashing-3.jpg
Respiratory Syncytial Virus. Retrieved from http
://www.corisbio.com/Products/Human-Field/RSV.php
Rsv protection. (2013). Retrieved from
https://www.rsvprotection.com/index.html
Respiratory syncytial virus. (2014, April 01). Retrieved from
http://www.cdc.gov/rsv/
Toon, John. (2013, December 30). Imaging Technology Could Unlock
Mysteries of a Childhood Disease. Retrieved formhttp
://www.news.gatech.edu/2013/12/29/imaging-technology-could-unlock-mysterie
s-childhood-disease
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REVIEW QUESTIONS
1. Which state/region has the longest duration of RSV season?A. FloridaB. Region 7C. Region 3
2. By what age have most children has RSV?A. 6 monthsB. 1C. 2
3. How long are you contagious after contracting the virusA. 1-2 daysB. 1-3 weeksC. 1 month