rxnorm and dailymed stuart j. nelson, md, facp, facmi
TRANSCRIPT
RxNorm and DailyMedRxNorm and DailyMed
Stuart J. Nelson, MD, FACP, FACMIStuart J. Nelson, MD, FACP, FACMI
What is RxNorm?What is RxNorm?
Public Domain VocabularyPublic Domain VocabularyStandardized (NORMalized) names for Standardized (NORMalized) names for
Clinical DrugsClinical DrugsSupports Interoperability Supports Interoperability Part of UMLSPart of UMLS
The Clinical Drug The Clinical Drug Problem (1)Problem (1)
Missed Synonymy in UMLSMissed Synonymy in UMLSHL7 DiscussionsHL7 DiscussionsClinical Drug DefinedClinical Drug Defined
– Ingredient plus Strength or Form or BothIngredient plus Strength or Form or Both
The Clinical Drug The Clinical Drug Problem (2)Problem (2)
Ciprofloxacin 100mg/50mL IV InfusionCiprofloxacin 100mg/50mL IV InfusionCiprofloxacin 400mg/200 ml IV InfusionCiprofloxacin 400mg/200 ml IV InfusionCiprofloxacin Lactate 0.2% in Saline Ciprofloxacin Lactate 0.2% in Saline
(Base Equiv)(Base Equiv)Ciprofloxacin IV Soln 2 MG/MLCiprofloxacin IV Soln 2 MG/MLThe Same, or Different?The Same, or Different?
Why Clinical Drugs?Why Clinical Drugs?
NDC CodesNDC Codes
– Too GranularToo Granular
– Incomplete RecordsIncomplete Records
– Meaningful IdentifiersMeaningful Identifiers
– Without Hyphens - Not UniqueWithout Hyphens - Not UniqueNo Source Complete and AccurateNo Source Complete and Accurate
NDC: 46193073801NDC: 00555046506NDC: 00555046505NDC: 00555046502NDC: 00054475833NDC: 00054475831NDC: 00054475825NDC: 54441019750NDC: 54441019725NDC: 54441019715NDC: 54441019711NDC: 54441019710NDC: 00182175810NDC: 00182175801NDC: 00228232796NDC: 00228232710NDC: 00046042199NDC: 00046042198NDC: 00046042195NDC: 00603548921NDC: 53258015313NDC: 54269010901NDC: 51813007299NDC: 51813007290NDC: 51813007260NDC: 53492301303NDC: 53492301302NDC: 53492301301NDC: 00591555404NDC: 00591555401NDC: 52493063960NDC: 00839711420
NDC: 00615256113NDC: 40039006001NDC: 00025090152NDC: 00025090131NDC: 47202255103NDC: 47202255101NDC: 12027008902NDC: 12027008901NDC: 53487014510NDC: 00781134413NDC: 00781134410NDC: 00781134401NDC: 53978003410NDC: 00117134405NDC: 00117134401NDC: 51316009004NDC: 11146094210NDC: 52544030551NDC: 52544030510NDC: 00839711416NDC: 00536430910NDC: 00536430905NDC: 00536430901NDC: 35470050801NDC: 00143150225NDC: 51608042104NDC: 51608042102NDC: 10465042109NDC: 00721002301NDC: 54421011001NDC: 19458042007NDC: 19458042001
NDC: 50053310901NDC: 47679070204NDC: 47679070201NDC: 46703009410NDC: 46703009401NDC: 52584018410NDC: 00363690810NDC: 53489045101NDC: 00157052610NDC: 00157052601NDC: 00054875825NDC: 00005310931NDC: 00005310923NDC: 00071007024 NDC: 00046042191NDC: 00046042181NDC: 00046042180NDC: 00046042162NDC: 00046042161NDC: 00046042160NDC: 00814644630NDC: 54697006305NDC: 54697006304NDC: 54697006303NDC: 54697006302NDC: 49884010601NDC: 00686018201NDC: 51079027760NDC: 00349845190NDC: 00349845110NDC: 00349845101NDC: 50053310902
NDC: 51285032190NDC: 51285032160NDC: 52985003606NDC: 52985003601NDC: 51285032112NDC: 51285032109NDC: 51285032105NDC: 51285032102NDC: 00555036505NDC: 00555036502NDC: 00308627099NDC: 00308627060NDC: 00308627030NDC: 54697006301NDC: 00302573210NDC: 11146091299NDC: 00719179413NDC: 00719179410NDC: 00904041180NDC: 00904041160NDC: 00894633104NDC: 00894633103NDC: 00894633102NDC: 00894633101NDC: 10647042101NDC: 50111046707NDC: 50111046703NDC: 50111046701NDC: 52555001010NDC: 52555001001NDC: 00093060010NDC: 00093060001
Propranolol10 Mg Oral
Tablet
NDC: 00686027720NDC: 48695117305NDC: 00047007032NDC: 0007007024NDC: 00223255002NDC: 00223255001NDC: 00364075690NDC: 00364075602NDC: 00364075601NDC: 52953000304NDC: 00378018210NDC: 00378018201NDC: 51432097106NDC: 00677104110NDC: 00677104105NDC: 00677104101NDC: 54569055650NDC: 00102333502NDC: 46193073810NDC: 46193073805NDC: 52544030505NDC: 52544030501NDC: 53633032116NDC: 53633032110NDC: 12071044010NDC: 54441004350NDC: 54441004325NDC: 54441004310NDC: 54441004305NDC: 54441004301NDC: 49884010610NDC: 49884010605
The RxNorm ModelThe RxNorm Model
Sources of Clinical Sources of Clinical Drug VocabulariesDrug Vocabularies
First DatabankFirst DatabankMultumMultumMicromedexMicromedexMediSpanMediSpanGold StandardGold StandardSNOMED-CTSNOMED-CTVA NDFVA NDFFDA - NDC Registry, DailyMedFDA - NDC Registry, DailyMed
Present StatusPresent Status
CoverageCoverage– Prescription Drugs (US)Prescription Drugs (US)
– 99% Complete99% CompleteBrowser (RxNav)Browser (RxNav)www.nlm.nih.gov/research/umls/rxnormwww.nlm.nih.gov/research/umls/rxnorm
Differences From UMLS Differences From UMLS
Normalized Names Establish SynonymyNormalized Names Establish SynonymyFrequent ReleasesFrequent ReleasesLimited ScopeLimited Scope
DailyMed BasisDailyMed Basis
Structured Product LabelsStructured Product LabelsFDA Approved InformationFDA Approved Information
What is a Product Label? What is a Product Label?
Content Approved by FDAContent Approved by FDAInformation for Prescribers/ DispensersInformation for Prescribers/ DispensersRarely Information for PatientsRarely Information for Patients
Product Label Distribution Product Label Distribution Old Method Old Method
Printed on Odd Shaped PaperPrinted on Odd Shaped PaperTiny PrintTiny PrintFolded to Postage Stamp SizeFolded to Postage Stamp SizeStuck Inside BoxStuck Inside BoxSome Printed in PDRSome Printed in PDRUpdates Erratic Updates Erratic
Product Label Distribution Product Label Distribution New Method New Method
Submitted and Processed ElectronicallySubmitted and Processed ElectronicallySent to NLMSent to NLMAvailable Online (Section 508 Available Online (Section 508
Compliant)Compliant)Downloadable for ReuseDownloadable for ReuseFirst Label November 1, 2005First Label November 1, 2005Easily UpdatedEasily Updated
Other Features of DailyMedOther Features of DailyMed
LinksLinks– PubMedPubMed
– MEDLINEplusMEDLINEplus
– ClinicalTrialsClinicalTrials
– Presence in Breast MilkPresence in Breast Milk
– Reporting Adverse EventsReporting Adverse EventsRxNorm Names and CodesRxNorm Names and Codes
DailyMed FunctionsDailyMed Functions
Download Product LabelsDownload Product LabelsPrint Product LabelsPrint Product LabelsForward LabelForward LabelSearch Archive for Old LabelsSearch Archive for Old LabelsNotify of Changes (RSS)Notify of Changes (RSS)
DailyMedDailyMed
