1) crowdfunding (but transitioning to subscription model)

2) venture philanthropy

3) patronage

How do we fund independent scientists whoaren’t named Darwin?

Targetophilia

Academia-Pharma Complex

by Naz Dana

an evolutionary approach

rare diseaseresearch

@experrinment

by Perrin Ireland

Personalizedmodel organisms

Patient-derived cells

One-stop shop for

rare disease drug discovery

• How much has decades of basic research on model organisms “de-risked” drug discovery, i.e., low-hanging fruit?

• What kind of hybrid business models and partnerships can be used to scale up rare disease drug discovery to all 7,000 diseases?

• Can patronage compete with venture capital and government grants?

A rare disease moon shot