scandinavian life sciences
TRANSCRIPT
Scandinavian Life Sciences Dr Rob Grundy, Head of Life Sciences.
www.ocoglobal.com
Scandinavia
• Constitutes Norway, Sweden and Denmark • Population: 20.5 million • European Union Members: Denmark (1973),
Sweden (1995) • Currency
• Denmark: Danish krone • Sweden: Swedish krona • Norway: Norwegian krone
• GDP • Denmark: $257bn • Sweden: $467.5 bn • Norway: $351.6 bn
Scandinavian Life Science – Strengths and Synergies
Particular overlapping interests/synergies with activity/strengths in Maine MedTech – Norway, Denmark Precision Medicine – Sweden, Denmark Marine biotechnology - Norway
Key areas of strength in Scandinavia
Pharmaceuticals – AZ, Novo Nordisk, LEO Pharma MedTech – Gambro, Elektra
Commercial world leaders in Scandinavia
AZ Novo Nordisk LEO Pharma
Scandinavian Life Science – Research Clusters
Scandinavian Life Science – M&A activity
Significant activity in pharma and medtech space
Steady increase in deal number Steady increase in deal size
Scandinavian Life Science – Recent partnerships
Denmark - Highlights
7 science parks 8 universities 75 hospitals (4 major university hospitals) 10,000 life science graduates annually 2,000 LS PhDs students graduating annually 25 CROs ≥ 160 core biotech companies ≥ 180 core medtech companies 48,000 employees in the life science industry
Mature Pharmaceutical sector NovoNordisk Leo Pharma Lundbeck
Strength in MedTech Hearing aid technology
Denmark - Universities
University of Copenhagen (KU) – Faculty of Health and Medical Sciences Technical University of Denmark (DTU) University of Southern Denmark (SDU) - Faculty of Health Sciences Aarhus University (AU) - Faculty of Health Sciences Aalborg University (AAU) – Faculty of Medicine
Denmark – Research Centers
Danish Center for Stem Cell Research (DanStem) Danish National Biobank European Spallation Source (ESS)
Denmark – Industrial Players
Pharmaceuticals NovoNordisk Lundbeck Leo Pharma Zealand Pharma Bavarian Nordic Neurosearch Genmab ALK-Abello Symphogen
Services Taconic Novozymes
MedTech Bang & Olufson Medicom Coloplast Dako - An Agilent Technologies Company GN ReSound Invacare Oticon Philips Healthcare Widex William Cook Europe
Denmark – Key Resources
Invest in Denmark – Life Sciences: http://www.investindk.com/Clusters/Life-Sciences/Biotech Danish Biotech Report: http://www.investindk.com/Home/News%20and%20events/News/2014/~/media/Files/Sheets/Life%20Sciences/Start%20With%20Denmark%202015_Full%20Report.ashx
Sweden- Highlights
Significant number of life science focussed Universities Karolinska Institute
Mature pharma/biotech sector AZ Swedish Orphan Biovitrum
Mature Medtech sector Gambro Elektra
Innovative healthcare systems
Sweden- Universities
Karolinska Institute Upsaala University Stockholm University Umeå University Lund University University of Gothenburg Linköping University
Sweden– Research Centers
Chemical Biology Consortium Sweden Umeå Centre for Microbial Research Umeå Plant Science Centre
Sweden– Industrial Players
Pharma/biotech Astra Zeneca Medivir Swedish Orphan Biovitrum Medivir Orexo Camurus Moberg Pharma Affibody Medical Bioarctic Neuroscience BioInvent Bioscience Alligator Bioscience InDex Pharmaceuticals
MedTech Getinge Gambro Elekta Mölnlycke Health care Nobel Biocare Permobil Etac Sectra Atos Medical Human Care
Sweden– Key Resources
Swedish Life Sciences Industry Guide: http://www.swedishlifesciences.se/ Swedish Drug Development Pipeline: http://swedenbio.se/wp-
content/uploads/2015/12/The-Swedish-Drug-Development-Pipeline-2015.pdf Business Sweden Life Sciences Sector: http://www.business-
sweden.se/en/Invest/industries/life-science/
Norway- Highlights
Oslo Cancer Cluster has global reputation for clinical trial opportunities
Progressive patient record system aids recruitment
Numerous research centres provide clear focus
Strength in imaging
Strength in marine science - SINTEF
Norway- Universities
Norwegian University of Life Sciences University of Oslo University of Bergen Norwegian University of Science and Technology University of Tromso
Norway – Research Centres
Oslo Cancer Cluster Centre for Molecular Biology and Neuroscience The Kavli Centre of Systems Neuroscience and The Centre of Biology of
Memory Medical Imaging Laboratory for Innovative Future Healthcare The Intervention Centre at Oslo University Hospital “Operating Rooms of the Future” project at St.Olav’s University Hospital in
Trondheim SINTEF HUNT Biosciences
Norway – Industrial Players
GE Imaging Lytix Cancer and Infection BerGenBio Target Identification & Small Molecules IsentioRipSeq Sequencing Technologies PCI Biotech Drug Delivery Affitech Antibody discovery platform DiaGenic Alzheimer's diagnostic Photocure Diagnostics & Small Molecules Bionor Labs Aquaculture, HIV Biotec Pharmacon Immune modulating compounds for the human health
sectors and marine enzymes used in molecular biology Biosergen Antifungals
Norway – Key Resources
Oslo Cancer Cluster: http://oslocancercluster.no/ Industrial Biotech Network – Norway: http://indbiotech.no/ Oslo Medtech: http://www.oslomedtech.no/
Medicon Valley
Medicon Valley
7 large R&D based pharma companies with local roots App.150 biotechs with own R&D App. 200 medtech companies More than 50 CROs and CMOs 33 hospitals (of which 11 are university hospitals) 44.000 life-science employees in the private sector 9 science parks 5 life science universities More than a dozen VCs with experienced life science teams
Focus on Precision Medicine/Diagnostics
Denmark home to Dako – an Agilent Company – world leading personalised medicine
reagents, software and device supply company
Several innovating pharma and biotech companies – a rich source of custom for the
diagnostics supply chain
Significant imaging activity in Norway and Denmark
Focus on Medical Products
Denmark is the second largest Medical Device market in Europe and by employment
per capita the second largest in Europe
A large share of Danish medical devices imports is incorporated into domestic
production and subsequently re-exported as finished products – these imports tripled
between 2001 – 2011
Norway – a medical imaging centre of excellence
Servicing the Market
Routes to collaborating Events: BIO Europe – Stockholm, April 4 – 6, 2016 Swedish American Chamber of Commerce http://www.sacc-usa.org/ Stockholm chamber of commerce http://english.chamber.se/
Distribution networks: Swedish distributer directory can be found at www.swedishlifesciences.se E.g. Christian Berner, distributer of IDEXX diagnostic kits
USA Pharma Exports into Norway (2014)
Product Label
Norway's imports from United States of America
Value in 2014, USD thousand Annual growth in value between 2010-2014, %, p.a. Share in Norway's imports, %
Medicament mixtures (not 3002, 3005, 3006), put in dosage 156183 11 10.2
Human & animal blood; antisera, vaccines, toxins, micro-organism culture 14070 -6 3.4
Pharmaceutical goods, specified sterile products sutures, laminaria 10850 9 13.1
Dressings packaged for medical use 3985 -1 8.5
Medicament mixtures (not 3002, 3005, 3006) not in dosage 1300 12 13.7
Glands & extracts, secretions for organotherapeutic uses; heparin & it 350 33 61.2
Trademap.org
Product Label Sweden's imports from United States of America
Value in 2014, USD thousand Annual growth in value between 2010-2014, %, p.a. Share in Sweden's imports, %
Medicament mixtures (not 3002, 3005, 3006), put in dosage 107493 21 3.6
Human & animal blood; antisera, vaccines, toxins, micro-organism culture 101696 11 10.6
Glands & extracts, secretions for organotherapeutic uses; heparin & it 95343 -7 96.3
Pharmaceutical goods, specified sterile products sutures, laminaria 1971 -3 1.5 Dressings packaged for medical use 1170 -23 0.9
Medicament mixtures (not 3002, 3005, 3006) not in dosage 39 -66 0.2
Trademap.org
USA Pharma Exports into Sweden (2014)
Product Label Denmark's imports from United States of America
Value in 2014, USD thousand Annual growth in value between 2010-2014, %, p.a. Share in Denmark's imports, %
Human & animal blood; antisera, vaccines, toxins, micro-organism culture 43775 10 5.6
Medicament mixtures (not 3002, 3005, 3006), put in dosage 31826 -12 1
Medicament mixtures (not 3002, 3005, 3006) not in dosage 10587 6 8
Glands & extracts, secretions for organotherapeutic uses; heparin & it 3397 -6 7.8
Dressings packaged for medical use 1900 7 1.7
Pharmaceutical goods, specified sterile products sutures, laminaria 1612 10 1.5
Trademap.org
USA Pharma Exports into Denmark (2014)
Case Study 1: PRA International
PRA International, a clinical research organisation, based in Raleigh, North Carolina. It specialises in oncology, respiratory/allergy, cardiovascular, and infectious diseases.
In June 2011 US-based clinical research firm PRA International opened a new office in Lund, Sweden. The new
branch provides quality clinical services across the region and allow the company to support growth of its business in Scandinavia. It is the company's first office in the country.
Motives cited: Industry Cluster / Critical Mass, Universities or researchers The Swedish office is located in the thriving region of Öresund, a hub for life science businesses. Öresund is centrally situated in the Medicon Valley, widely known as one of Europe’s primary centres for biotech and pharmaceutical activity. The region is also home to several top universities, providing access to leading academic research.
fDi Markets
Sapheneia, a medical software company based in Dillon, Colorado. Sapheneia, set up a base in Linköping to carry out research and development in medical technology. The R&D centre will initially employed 5 people, but there were 10 members of staff by the end of 2006.
Motives cited: Universities or researchers Sapheneia, which has developed a technique for removing hard-to-reach tumours, says it is setting up at the Mjärdevi Science Park to take advantage of Linköping’s research environment. “We want to be close to the specialist competence in image manipulation and visualization present in the region, particularly at Linköping University,” said Hans Grahn, Vice President of International Growth & Development at Sapheneia.
fDi Markets
Case Study 2: Sapheneia
Concluding Thoughts
Numerous pharma and biotech players with which to engage for the provision of precision medicine solutions
Innovative healthcare systems where evidence based value is easily adopted
Many med tech providers looking for OEM componentry
A region committed to the life sciences
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